This Week in Microbiology

By Vincent Racaniello

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Category: Natural Sciences

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This Week in Microbiology is a podcast about unseen life on Earth.

Episode Date
TWiM 178: Corals are sexy with Christina Kellogg
01:04:48

The TWiM team travels to ASM Microbe 2018 in Atlanta, Georgia to speak with Christina Kellogg about her career and her research on coral microbial ecology.

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson

Guest: Christina Kellogg

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

Jun 15, 2018
177: Microbial sibling conflict
54:38

The TWiM team discuss bacteriophage evolution in a dairy plant, and killing of less fit cells among social microbes.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Elio Schaechter.

Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

Jun 01, 2018
176: Elio has lots of colanic acid
59:48

Vincent, Michael and Elio note the passing of Stanley Falkow, give E. coli an archaeal membrane, and show how the microbiome can make worms live longer.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

May 17, 2018
175: Neomycin is antiviral
01:03:06

The TWiM team notes the passing of Allan Campbell, and explains how aminoglycoside antibiotics like neomycin enhance host resistance to viral infection.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Michele Swanson.

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May 02, 2018
174: A Gathering Typhoid Storm
01:02:25

The TWiMsters explain why untreatable typhoid fever might be on the way, and the evolution of fungal virulence in tropical frogs.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

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Apr 19, 2018
173: Gee whiz in style
58:34

The Masters of the Microbiological Universe discuss the humongouest fungus, and a commensal bacterium that protects against skin neoplasia.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Mar 30, 2018
172: Unfolding relaxases and soil malacidins
01:13:32

The TWiMmers discuss culture-independent discovery of malacidin antibiotics, and unfolding of relaxase during bacterial conjugation.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Mar 15, 2018
171: If you give a bee a fungus
01:00:33

The TWiM team explores a stingless bee that requires a fungal steroid to pupate, and colonic biofilms containing tumorigenic bacteria in patients with colorectal polyps.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

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Feb 22, 2018
170: Rats, lice, and nanoparticles
55:54

The TWiM team reveals that spread of plague was likely by human ectoparasites, not rats, and deconstruct a durable, broadly protective protein nanoparticle influenza virus vaccine.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

 

Feb 08, 2018
169: Breatharian Bacteria
01:02:28

The cast of TWiM reveals how uropathogenic E. coli use a copper-binding protein to treat copper as a nutrient or a toxin, and Antarctic soil bacteria that survive on trace atmospheric gases.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Jan 23, 2018
TWiM #168: The lesser of two weevils
01:16:35

Dickson joins the TWiM team to discuss the nasal microbiota of dairy farmers, and attenuation of bacterial virulence by quorum sensing in the maize weevil.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Michele Swanson.

Guest: Dickson Despommier

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Jan 05, 2018
TWiM #167: I have one word for you: Flink
52:40

How pandemic influenza viruses suppress immunogenic cell death, and 3D printing of bacteria into functional materials.

Dec 22, 2017
TWiM #166: Dark fermentation
51:13

Vincent and Elio discuss the reason for poor efficacy of one of the influenza virus vaccines, and using a hyperthermophilic anaerobe to produce hydrogen from fruit and vegetable wastes in seawater.

Hosts: 

Vincent Racaniello and Elio Schaechter.

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Dec 07, 2017
TWiM #165: Pumping Copper
01:03:19

The TWiM team discusses the use of copper on exercise weights to reduce bacterial burden, and the mechanism of antigenic variation by which a fungus that causes severe pneumonia escapes the immune system.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson

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Nov 30, 2017
TWiM #164: Indiana Quorum
59:10

From Indiana University, Vincent speaks with Ankur, Julia, and Xindan about their careers and their work on horizontal gene transfer, quorum sensing, and chromosome organization in bacteria.

Guests: Ankur Dalia, Julia Van Kessel, and Xindan Wang

Watch the video version! https://www.youtube.com/watch?v=ifGCe-qfnA0

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Nov 16, 2017
TWiM #163: Saliva and sptR/S
01:06:17

This episode is all about saliva: how certain bacteria survive in it, and how swallowing saliva might cause intestinal inflammation.

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Nov 02, 2017
TWiM #162: Intracellular bacteria with flagella
52:42

The TWiM hosts and associated microbiomes review a fungus destroying salamanders in Europe, and genes for flagella in intracellular bacteria.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

 

Oct 13, 2017
TWiM #161: Eros, a bacterial aphrodisiac
55:56

From the TWiM team, a discussion of Hurricane Harvey microbiology, and a bacterial enzyme that induces eukaryotic mating.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a patron of TWiM. Two S. rosetta cells touching, a prelude to mating

Links for this episode

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

Sep 21, 2017
TWiM #160: On the road to virus
01:07:04

The TWiM team provides an update on Zika virus, and reveals a plasmid on the road to becoming a virus.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Michele Swanson.

Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a patron of TWiM.

Links for this episode

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

Sep 08, 2017
TWiM #159: Immunophage synergy
01:00:36

The TWiM team pays a tribute to Chris Condayan, and investigates the synergy between virus and the innate immune system for clearing bacterial pneumonia by phage therapy.

Aug 31, 2017
TWiM #158: The bottom line
01:05:01

The TWiM team considers a report on prokaryotic viral DNA in mammalian brain, and how diarrhea is beneficial, by clearing enteric pathogens.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Links for this episode

 

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

 

Aug 10, 2017
TWiM #157: Back to the ancestor
56:43

The TWiMbionts explore the role of bacteria in the genesis of moonmilk, and how ancient host proteins can be used to engineer resistance to virus infection.

Hosts: 

Vincent Racaniello, Michele Swanson and Elio Schaechter.

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 Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

 

Jul 27, 2017
TWiM #156: Gifted microbes and defensive symbiosis
57:56

The TWiM team explains the use of microbial genome mining to identify new drugs, and how a bacterial symbiont protects flies against parasitoid wasps.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Jul 13, 2017
TWiM #155: Living in the stomach of a cell
57:28

Michele updates the TWiMers on Legionella in the Flint water supply, and Elio informs us about how horizontally acquired biosynthesis genes boost the physiology of Coxiella burnetii.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Jun 29, 2017
TWiM #154: Rigor, lotteries, and moonshots
01:14:22

At Microbe 2017 in New Orleans, the TWiM team speaks with Arturo Casadevall about his thoughts on the pathogenic potential of a microbe, rigorous science, funding by lottery, and moonshot science.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

Watch the video version recorded live at ASM Microbe 2017!

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Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

Jun 14, 2017
TWiM #153: Covert pathogenesis
57:35

The TWiM team ventures into preprint space with an analysis of type VI secretion across human gut microbiomes, and provide insight into urinary tract infection: how bladder exposure to a member of the vaginal microbiota triggers E. coli egress from latent reservoirs.

Hosts: 

Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter.

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Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

May 30, 2017
TWiM #152: Wooden steps
51:09

The TWiMmers get cozy with symbionts: the bacteria that allow a giant shipworm to oxidize sulfur, and algae that live within salamander cells.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

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May 19, 2017
TWiM #151: Bat and moth antimicrobials
59:49

The TWiMsters discuss potential new sources of antimicrobial compounds from unusual places: the skin of bats and the intestines of moths.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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May 04, 2017
TWiM #150: Microbiology is where it’s at
01:01:21

In recognition of National Medical Laboratory Professionals Week, Robin Patel speaks with the TWiM team about directing a clinical bacteriology laboratory, and how an observation made by a laboratory technologist lead to the finding that Ureaplasma species can cause a system metabolic disturbance, hyperammonemia.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson

Guest: Robin Patel

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Apr 20, 2017
TWiM #149: You’re going to learn R
01:02:54

The TWiM team speaks with Pat Schloss about assigning sequence data to operational taxonomic units, and his experience with mSphere Direct, a new way of submitting papers for publication.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Special guest: Pat Schloss

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This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

Apr 06, 2017
TWiM #148: Neanderthal Dentistry
55:28

Vincent, Elio, and Michael reveal what Neanderthals ate from analysis of DNA in their teeth, and new CRISPR-Cas systems found in the genomes of uncultured microbes.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

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This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv 

Mar 23, 2017
TWiM #147: The Public Goods Dilemma
01:06:38

The TWiM hosts reveal why phosphorus is essential for fungal brain disease, and how bacteria kill local competitors to favor the evolution of public goods cooperation.

Hosts: 

Vincent Racaniello, Michele Swanson, Michael Schmidt, and Elio Schaechter.

Links for this episode

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This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Mar 10, 2017
TWiM #146: Viral arbitrium
53:57

Vincent, Elio and Michael discuss the finding of a prion in bacteria, and how communication between bacteria guides the decision between lysis and lysogeny.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Feb 23, 2017
TWiM Special: Q fever with Robert Heinzen
01:04:51

Host: Vincent Racaniello

Guest: Robert Heinzen

At the Rocky Mountain Laboratory in Hamilton, Montana, Vincent speaks with Robert Heinzen about the work of his laboratory on Q fever and its causative microbe, Coxiella burneti.

 

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

Feb 16, 2017
TWiM #145: Anything but academic
01:02:44

Vincent meets up with Catharine Bosio, Michael Merchlinsky, and Shilpa Gadwal at the ASM Biothreats meeting to talk about careers for scientists outside of the ivory tower.

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Feb 09, 2017
TWiM #144: Did eukaryotes invent anything?
01:06:04

The TWiMers discuss how changes in domestic laundering affect the removal of microorganisms, and assembly of a nucleus-like structure during viral replication in bacteria.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Jan 26, 2017
TWiM #143: E-scaffolds and receptor transfer
01:05:42

Vincent, Michael, and Michele explain the use of an electrochemical gradient to eliminate bacterial biofilms, and how phage susceptibility can be transferred by exchange of receptor proteins.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Michele Swanson.

Right click to download TWiM#143 (32 MB .mp3, 66 minutes).

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This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv 

Jan 12, 2017
TWiM #142: A membrane-thickness caliper
58:37

Vincent, Elio and Michele wind up a year of microbial podcasts with a story about the lack of resistance to a crop antifungal compound, and how a bacterium uses a molecular caliper to measure membrane thickness.

Hosts: 

Vincent Racaniello, Elio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv 

Dec 29, 2016
TWiM #141: Nutritional immunity and polymicrobial infections
01:05:54

Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.

Hosts: 

Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

Guest: Jennifer Bomberger

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This show is sponsored by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. This Holiday season give someone a Drobo to keep all their files and memories safe forever

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Dec 15, 2016
TWiM 140: Small town, big science
01:20:13

Host: Vincent Racaniello

Guests: Marie Antonioli, Bryan Hansen, Forrest Jessop, Kyle Shifflet and Jim Striebel

At the Hamilton, Montana Performing Arts Center, Vincent speaks with three local high school graduates and two high school teachers about how Rocky Mountain Laboratories influenced school science programs and opened up career opportunities.

 

Subscribe to TWiM (free) on iTunesStitcherAndroidRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

Dec 01, 2016
TWiM #139: Frackibacter and sticky fingers
01:11:27

The TWiM team discusses microbial DNA found on ATM machines in New York City, and how hydraulic fracturing, or fracking, alters microbial ecosystems deep in the Earth.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Register today for the 2017 ASM Scientific Writing and Publishing Online Course at bit.ly/swpoc17

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Nov 18, 2016
TWiM #138: Learning to love uranium and the A-baum
01:02:09

The TWiM team brings you a bacterium from a Colorado field site that grows on uranium, and copper resistance in the emerging pathogen Acinetobacter baumannii.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Nov 03, 2016
TWiM #137: The battle for oxygen
01:08:54

Highlights of the Recent Advances in Microbial Control meeting in San Diego, and expansion of a gut pathogen by virulence factors that stimulate aerobic respiration.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Oct 20, 2016
TWiM #136: Diderms and then monoderms
48:43

Them TWiM team discusses the importance of neutrophils in microbial infections, and evidence that ancient bacteria had two cell walls.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Oct 07, 2016
TWiM #135: Unruly individuals and their unruly friends
01:06:41

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Sep 23, 2016
TWiM #134: Lipids that live forever
01:04:23

Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Sep 08, 2016
TWiM #133: Right under our noses
01:01:03

Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

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Image in audio player: Molecular surface of a Human rhinovirus, showing protein spikes. By: Wiki user: Robin S

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Aug 20, 2016
TWiM #132: Bacteria learn long division
57:25

Vincent, Elio, and Michele present cell division by longitudinal scission in an insect symbiont, and thermally activated charge transport in microbial nanowires.

Hosts: Vincent RacanielloMichele Swanson and Elio Schaechter.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Aug 05, 2016
TWiM 131: Mice behaving badly
01:22:09

Hosts: Vincent Racaniello and Michael Schmidt

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

 

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

Jul 20, 2016
TWiM #130: Interkingdom interactions at ASM Microbe
01:17:28

Filmed live in Boston, MA at Microbe 2016, David S. Schneider and Vanessa Sperandio talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.

Jun 23, 2016
TWiM #129: Dried and wrinkled, smooth and mucoid
01:10:40

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Image: Etest used to determine the minimum inhibitory concentration of an antibiotic for a particular bacterium.

Hosts: Vincent RacanielloMichael Schmidt, and Michele Swanson. 

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

Jun 07, 2016
TWiM #128: A moonlighting phage protein
01:17:35

A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.

Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.TWiV agar art

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completel free if you sign up at curiositystream.com/m​icrobe ​and use the promo code MICROBE​.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

May 21, 2016
TWiM #127: Subway Snowblowers and Men in Black
54:27

The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.

Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent and orange floc on the seafloor. Credit: Canadian Scientific Submersible Facility and the University of Washington

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

snowblower vent800

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This episode is sponsored by ASM Agar Art Contest and ASM Grant Writing Course

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 

May 05, 2016
TWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)
01:07:00

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

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Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

Apr 22, 2016
TWiM #125: A minimal cell operating system
57:50

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.

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Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

 

Apr 07, 2016
TWiM #124: Fungal pirates
01:03:15

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

 

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Mar 24, 2016
TWiM #123: A microbial MAGE
01:15:28

Hosts: Vincent RacanielloMichael Schmidt, and Elio Schaechter.

Guest: Harris Wang

Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.

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Links for this episode 

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

 

Mar 09, 2016
TWiM #122: Mayonii, microRNAs and the microbiome
01:03:33

Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome.

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Links for this episode

Identification of a novel Borrelia species causing Lyme disease (Lancet Inf Dis)

Parasite wonders with Bobbi Pritt (TWiP 75)

Reported cases of Lyme disease (CDC)

Signs and symptoms of Lyme disease (CDC)

Multilocus sequence typing

Borrelia MLST database

American Academy of Microbiology FAQ Human microbiome

Host fecal microRNA shapes gut microbiota (Cell)

Image credit

C.U.R.E. the game

Live Tiny, Die Never - Tardigrade T-shirt

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

Feb 25, 2016
TWiM #121: A plague of pathogens
57:52

Host: Vincent Racaniello

Special guests: Rebekah Kading and Wyndham Lathem

From the ASM Biodefense and Emerging Diseases Research meeting, Vincent speaks with Rebekah and Wyndham about their work on Rift Valley Fever virus and other vector-borne pathogens, and the evolution and pathogenesis of Yersinia pestis, the agent of plague.

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Links for this episode 

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Feb 11, 2016
TWiM #120: Snakes in trouble
49:02

Hosts: Vincent Racaniello and Elio Schaechter.

Vincent and Elio marvel in the finding that a phage tail-like structure from a marine bacterium stimulates tubeworm metamorphosis, and reveal Ophidiomyces as a cause of snake fungal disease.

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Links for this episode 

This episode is sponsored by ASM Grant Writing Institute Online Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

 

Feb 02, 2016
TWiM #119: Power of one
01:03:25

Hosts: Vincent RacanielloMichael Schmidt, and Elio Schaechter.

The microbophiles investigate the ratio of bacterial to human cells in our bodies, and how placing solar panels on a bacterium enables it to carry out photosynthesis.

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Links for this episode 

This episode is sponsored by ASM Grant Writing Institute Online Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

Thumbnail image: Cell structure of a gram positive bacterium. This vector image is completely made by Ali Zifan - Own work; used information from Biology 10e Textbook (chapter 4, Pg: 63) by: Peter Raven, Kenneth Mason, Jonathan Losos, Susan Singer · McGraw-Hill Education.

 

Jan 16, 2016
TWiM #118: Spore-drops keep fallin’ on my head
01:05:35

Hosts: Vincent Racaniello, Elio Schaechter and Michele Swanson

On the last episode for 2015, Vincent, Elio, and Michele discuss how soil amoeba hunt nematodes in packs, and the role of mushrooms as rainmakers.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

This episode is sponsored by ASM Microbe 2016 and ASM Biodefense

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

Jan 01, 2016
TWiM #117: Finding the comammox
01:10:28

The TWiM team marvels over the finding of a completely nitrifying Nitrospira, and horizontal gene transfer from Wolbachia into an animal genome.

Links for this episode:


This episode is sponsored by ASM Microbe 2016 and ASM Biodefense

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

Dec 17, 2015
TWiM #116: Chewates and coconuts
01:00:58

Hosts: Vincent RacanielloElio Schaechter and Michele Swanson

The TWiMeriti reveal a Brazilian social bee that must cultivate a fungus to survive, and diet-mediated reduction in gut colonization by Candida albicans.

Links for this episode 

This episode is sponsored by ASM Biodefense and the 32nd Clinical Virology Symposium.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

Dec 02, 2015
TWiM #115: Profiling the Poglianos
56:23

Vincent visits the laboratories of Kit and Joseph Pogliano on the campus of the University of California, San Diego, where he learns about their work on the bacterial cytoskeleton, sporulation, and the effects of antibiotics on bacterial cells.

Visit microbeworld.org/twim for complete shownotes including the special video version of this episode. Thanks for listening and watching!

Nov 20, 2015
TWiM #114: Milestones in Blue
01:11:00

Vincent, Elio, and Michele meet with Harry Mobley, Mary O’Riordan, and Vince Young at the University of Michigan, during the designation of the Department of Microbiology and Immunology as a Milestones in Microbiology site. They discuss how the laboratory has advanced the science and teaching of microbiology, and discuss faculty work on uropathogenic E. coli, induction of stress by bacterial infection, and the gut microbiome.

Visit microbeworld.org/twim for more including the special video version of this episode.

Nov 06, 2015
TWiM #113: Waves of Change
53:46

Vincent meets up with Romney and Duncan at the 79th annual meeting of the Southern California branch of the American Society for Microbiology, where they talk about emerging technologies for antimicrobial susceptibility testing, and next generation sequencing and advanced molecular diagnostics.

Visit microbeworld.org/twim to watch the video version and for complete shownotes including links mentioned.

Oct 22, 2015
TWiM #112: Mushroom pickers and mushroom kickers
01:00:42

The TWiM team wonders why definitions in biology often change, and discuss how the small molecule terrein is important for the growth of a soil fungus.

Image: Lesion formation on banana surfaces infected with Aspergillus terreus. Source

Links mentioned:

 

Visit microbeworld.org/twim for more.

 

Sep 26, 2015
TWiM #111: Ancientbiotics and modernbiotics
59:02

Hosts: Vincent RacanielloMichael Schmidt, and Elio Schaechter.

The TWiMitos discuss the reconstruction of a 1,000-year-old antimicrobial remedy, and using gallium as an antimicrobial in the battle for iron.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Sep 10, 2015
TWiM #110: Exploring unseen life with unpronounceable words
01:11:45

The TWiM team focuses on the gut microbiome, from a single member, Akkermansia muciniphila, to the effect of antibiotics on its composition and colonization resistance against C. difficile.

Subscribe to TWiM (free) on iTunesStitcherAndroidRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

Agar art contest

Akkermansia muciniphilia and obesity (Gut)

A. muciniphilia genome (Biol Direct)

Alterations of gut microbiota and C. difficile colonization (mBio)

Science Delivered

Girls Who Code

F.E.M.M.E.S.

Association for Women in Science

UMich Host-Microbiome Initiative

UMich anaerobic chamber room (png)

Aug 19, 2015
TWiM #109: Precision killing
01:08:52

The TWiM cohort discusses the use of antimicrobial peptides to target specific bacteria in the microbiome, and how the intracellular bacterium Wolbachia selectively kills male hosts.

 

Links for this episode:

 

Image: Transmission electron micrograph of Wolbachia within an insect cell.

By: Scott O'Neill - Genome Sequence of the Intracellular Bacterium Wolbachia. PLoS Biol 2/3/2004: e76.

Aug 06, 2015
TWiM #108: Vaccine in the time of cholera
01:12:13

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson.  

The professors of TWiM discuss a University of Wisconsin plan for rescuing biomedical research in the US, and results of a clinical trial in Bangladesh of an oral cholera vaccine.

Subscribe to TWiM (free) on iTunesStitcherRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Jul 23, 2015
TWiM #107: The battle in your bladder
01:31:06

Hosts: Vincent Racaniello and Michael Schmidt.

Vincent and Michael discuss the highly diverse microbiome of uncontacted Amerindians, and how the composition of human urine plays a role in the battle for iron.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Jul 09, 2015
TWiM #106: Lawn mower disease
01:16:32

 

Vincent and Michael speak with Katy Bosio about her research on pathogenesis, immunity, and vaccines against Franciscella tularensis, the causative agent of tularemia.

Jun 24, 2015
TWiM #105: Real bugs with legs
57:54

The TWiM team reviews the microbiological safety of herbs in the United Kingdom, and how a peptide from the milkweek bug binds the ribosome and inhibits bacterial protein synthesis.

 

Links for this episode:

 

Jun 05, 2015
TWiM #104: Feed me polyamines, biofilm
01:03:49

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson.  

The TWiM team discusses how measles vaccination protects against other infectious diseases, and links between bacterial biofilms and colon cancer.

Subscribe to TWiM (free) on iTunesStitcherRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Measles vaccination prevents all-cause infectious disease (Science)

Master of contagion (The Loom)

Video: Measles incidence to immunomodulation (Science)

FAQ: Adult vaccines

Metabolism links biofilms and colon cancer (Cell Metab)

Scripps Center for Metabolomics

Scripps metabolite database

Image credit

Sponsors for this episode: SciMedSolutionsICAAC-ICC

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

May 21, 2015
TWiM #103: The battle for iron
01:05:50

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

The TWiM team is amazed by the ocelloid, and an evolutionary battle for iron between mammalian transferrin and bacterial transferrin-binding protein.

Subscribe to TWiM (free) on iTunesStitcherRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

May 08, 2015
TWiM #102: Happiness is the spore-formers in your gut
57:43

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

The TWiM team discusses evidence that serotonin synthesis is regulated by spore-forming members of the gut microbiota.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Image: Serotonin temporary tattoo by flickr user: ChezShawna

 

Apr 24, 2015
TWiM #101: The MRSA in your home
01:14:44

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

The TWiMers discuss how aroma helps disperse yeast cells on insect vectors, and evidence that MRSA is transmitted within households.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

Apr 01, 2015
TWiM #100: Omnis cellula e cellula
50:38

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Jo Handelsman.  

The TWiM team celebrates 100 episodes with a Talmudic question, and discussion of how a single mutation alters bacterial host tropism.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Image: Yellow colonies of S. aureus on a blood agar plate, note regions of clearing around colonies caused by lysis of red cells in the agar By: HansN. on wikimedia. From the study (Nat Gen) "...only a single naturally occurring nucleotide mutation was required and sufficient to convert a human-specific S. aureus strain into one that could infect rabbits." 

Mar 18, 2015
TWiM #99: Careers in Biodefense
01:01:56

Hosts: Vincent Racaniello

Guests: Maria Julia MarinissenEdward H. You, and David R. Howell

Vincent meets up with Maria, Edward, and David at the ASM Biodefense and Emerging Infections Research meeting to talk about alternative careers for scientists.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

 

A video version of this episode is available at microbeworld.org/twim 

Links for this episode:


Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Mar 04, 2015
TWiM #98: Bacteria and eukaryotes get horizontal
58:37

 

The TWiM crew ponders the question of how a bacterium finds its middle when dividing, then divulge the transfer of interbacterial antagonism genes to eukaryotes, where they may function in innate defense.

 

Links for this episode:

 

Visit microbeworld.org/twim for complete shownotes and more.

Feb 19, 2015
TWiM #97: There’s gold in them hills
01:14:23

The TWiM team reveal how bacteria in a shipworm’s gills help digest wood in the gut, and an approach that identifies a new antibiotic from the soil.

 

Links for this episode:

 

Visit microbeworld.org/twim for more.

Feb 04, 2015
TWiM #96: A lean, mean sequencing machine
54:39

Hosts: Vincent Racaniello.

Special guest: Rob Knight

Vincent meets up with Rob Knight to talk about the technology that has fueled his drive to sequence the Earth and its inhabitants.

Check out the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Jan 21, 2015
TWiM #95: A microbe lover in San Diego
01:06:22

Hosts: Vincent Racaniello.

Special guest: Stanley Maloy

Vincent meets up with Stan Maloy on the campus of San Diego State University to talk about his career in microbiology and his work as Dean of Science.

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Links for this episode: 

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

Jan 09, 2015
TWiM #94: Nitrochondria
01:06:50

Vincent, Elio, and Michael discuss a symbiosis between a nitrogen-fixing cyanobacteria and a single-celled eukaryotic alga.

 

Links for this episode:

 

Visit microbeworld.org/twim to view the complete shownotes and entire back catalog.

Dec 25, 2014
TWiM #93: Worming in on bacteria
56:30

 

Vincent, Elio, and Michael reveal that a soil-dwelling nematode can recognize and respond to a bacterial quorum sensing molecule through a sensory neuron.

Dec 11, 2014
TWiM #92: Flying biofilms
01:08:06

Vincent, Elio, Michael and Michele discuss the possible eradication of wild poliovirus type 3, and how microsporidian parasites prevent locust swarming behavior.

 

Nov 27, 2014
TWiM #91: Rats, viruses, and bacteria
58:32

Vincent, Elio, and Michele review a study of the viruses and bacteria in commensal rats in New York City.

Visit microbeworld.org/twim for complete show notes. Thanks for listening!

Nov 14, 2014
TWiM #90: Think globally, act locally
01:02:15

 

Vincent meets up with Laurene and David at the Annual Meeting of the Southern California Branch of the American Society for Microbiology, where they discuss how the Los Angeles County Department of Health is preparing for an outbreak of Ebola virus infection, and Cepheid’s game-changing, modular PCR system for the diagnosis of infectious diseases.

Oct 29, 2014
TWiM #89: Microbial handoffs
01:13:14

Vincent, Michele, and Michael discuss how a gene from bacteria protects a tick from plant cyanide poisoning, and enhanced transmission of Streptococcus pneumoniae by influenza virus co-infection in mice.

Oct 15, 2014
TWiM #88: A century of excellence in microbiology
50:26

Michele speaks with members of the Department of Bacteriology at the University of Wisconsin - Madison, on the occasion of its designation as a Milestones in Microbiology site, where they discuss how the department has advanced the science and teaching of microbiology.

 
Oct 01, 2014
TWiM #87: Avogadro, archaeal fossils, and ICAAC
01:14:14

Vincent, Elio, and Michael explore the fossilization of archaeal lipids, and highlight the recent ICAAC in Washington, D.C.

 
Sep 17, 2014
TWiM #86: Blurring the line between organelle and endosymbiont
01:12:06

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

Vincent, Elio, Michael, and Michele consider whether our eating behavior is manipulated by gastrointestinal microbiota, and an aphid gene of bacterial origin whose gene product encodes a protein that is transported to an obligate endosymbiont. 

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Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Sep 03, 2014
TWiM #85: Oscillation in the ocean and a Verona integron
01:17:48

Vincent, Elio, Michael, and Michele discuss the diel transcriptional rythmns of bacterioplankton communities in the ocean, and extensively drug resistant Pseudomonas in Ohio.

Aug 21, 2014
TWiM #84: Microbiology Down Under
01:08:43

In Melbourne, Australia Vincent speaks with David, Melanie, and Adam about their work on group A Streptococcus, Helicobacter pylori, and infections of Koalas with Chlamydia.

Aug 11, 2014
TWiM #83: Illuminating tuberculosis and cryptococcosis
01:19:09

Vincent, Michael, Elio and Michele review a new fluorogenic diagnostic test for tuberculosis bacteria, and the role of a metalloprotease in helping a fungus invade the central nervous system. 

 
Jul 24, 2014
TWiM #82: Betrayal and compromise
01:11:48

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson.

Vincent, Michael, Elio and Michele discuss how an endosymbiont betrays its aphid host to alert plant defenses, and a new immunosuppressive cell that allows infection of neonates.

 

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Jul 10, 2014
TWiM #81: Cold iron is the master of them all
01:11:23

Vincent, Michael, and Michele discuss how iron might disperse bacterial biofilms in carotid arterial plaques, and controlling Salmonella by modulating host iron homeostasis. 

Jun 28, 2014
TWiM #80: Hurling fleas and designer chromosomes
54:11

Hosts: Vincent RacanielloElio Schaechter, and Michele Swanson

Vincent, Elio, and Michele discuss how to synthesize a designer yeast chromosome, and deciphering the genetic changes path that allowed Yersinia pestis to be transmitted by fleas.

Links for this episode:

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Jun 11, 2014
TWiM #79: A community of microbiologists
01:11:32

Vincent, Michael, and Michele review highlights of the 2014 General Meeting of the American Society for Microbiology in Boston, MA.

May 29, 2014
TWiM #78: A bacterium grows in Brooklyn
01:03:57

Vincent, Elio, and Michael consider a fungal pathogen of insects that acquired a gene from its host that facilitates infection, and presence of gram-negative nosocomial pathogens on community surfaces near hospitals in Brooklyn. 

May 15, 2014
TWiM #77: Zombie plants and no pain, no gain
01:08:21

Vincent, Elio, Michael, and Michelle review how a pathogen promotes plant attractiveness to insect vectors, and activation of sensory neurons that modulate pain and inflammation by bacterial infection.

 
May 01, 2014
TWiM #76: Genetic biopixels and a pathogenic sweet tooth
01:07:29

Vincent, Elio, Michael, and Michelle discuss the use of bacteria to build a genetic sensor for heavy metals, and how host sugars help enteric pathogens to expand after antibiotic treatment.

 
Apr 11, 2014
TWiM #75: Pellicles on pickle jars
01:21:51

Vincent, Elio, Michael, and Michelle discuss a symbiosis between a bacterium and fungus that increases the virulence of oral biofilms, and the assembly of amyloid fibers, which are needed for biofilm formation.

 
Mar 27, 2014
TWiM #74: It came from the Siberian permafrost
01:10:14

Vincent, Elio, and Michael discuss a huge 30,000 year old virus recovered from Siberia, and nested symbiosis facilitated by horizontal gene transfer from bacteria to insect.

Mar 12, 2014
TWiM #73: Eyeing root nodule development
01:19:38

Vincent, Michael, and Michele discuss how soil-dwelling bacteria induce the formation of root nodules on legumes via a protein called CYCLOPS. 

Feb 27, 2014
TWiM #72: The benefits of virulence
01:14:10

Vincent, Elio, Michael, and Michele review how microbial virulence can be increased as a consequence of community surveillance and adaptation to macrophages.

 
Feb 13, 2014
TWiM #71: Colon cancer’s little shop of horrors
01:18:38

Vincent, Michael, and Michele explain how the gut microbiome modulates colon tumorigenesis, and regulation of intestinal macrophage function by the microbial metabolite butyrate.

Jan 22, 2014
TWiM #70: A paroxysmal cough
01:13:12

Vincent, Elio, Michael, and Michele discuss evidence that the acellular pertussis vaccine fails to prevent infection and transmission in nonhuman primates, and the use of bacterial cytological profiling to identify pathways targeted by antibiotics.

Dec 18, 2013
TWiM #69: Bacterial DNA in the human genome
01:09:42

Vincent, Elio, Jo, and Michele review evidence for bacterial DNA integrated into the human genome, and control of the symbiont population in an insect midgut.


Nov 27, 2013
TWiM #68: The fungus among us
01:11:23

Vincent, Elio, Michael, and Michele discuss the amazingly high level of intergenera gene exchange among haloarchaea in an Antarctic lake, and the diversity of fungi on residential surfaces and the human forehead. 

Nov 14, 2013
TWiM #67: Black mushrooms and RNA thermosensors
01:15:30

Vincent, Elio, and Michael discuss how temperature triggers Neisseria menigitidis immune evasion, and protection of mice from ionizing radiation by feeding them black mushrooms.

Oct 30, 2013
TWiM #66: The shape of a container
01:08:58

Vincent, Elio, Michael, and Michele discuss the curious outer membrane vesicles of Neisseria meningitides, and sources of Clostridium difficile infection revealed by genome sequencing.

Oct 17, 2013
TWiM #65: Leanness is transmissible
51:11

Hosts: Vincent Racaniello and Michelle Swanson.

Vincent and Michelle reveal how the human gut microbiota can modulate obesity in mice.

Links for this episode: 

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Oct 03, 2013
TWiM #64: URI and UTI at ICAAC in Denver
01:18:00

Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli.


Sep 18, 2013
TWiM #63: Superantigens, S. aureus, and the armpit microbiome
01:26:01

Vincent, Michael, and Michelle discuss how a Staphylococcus aureus superantigen is critical for pathogenesis in a rabbit model, and the relationship of body odor to the axilla microbiome.

Sep 04, 2013
TWiM #62: Breaking bad and protein chain mail
01:19:54

Vincent and Michael discuss how infection with influenza A virus disperses Streptococcus pneumoniae biofilms leading to disease, and an amazing protein chainmail in a viral capsid 

Aug 21, 2013
TWiM #61: The irony of probiotics
59:38

Vincent, Elio, and Michele review how horizontal gene transfer from bacteria to an insect genome enables a tripartite nested mealybug symbiosis, and how probiotic bacteria work by competing for iron in the intestine.

Aug 07, 2013
TWiM #60: Microbial electrochemistry and diversity-generating retroelements
01:11:29

Vincent, Elio, and Michael discuss how an error-prone reverse transcriptase produces enormous diversity in a Legionella protein, and using microbes to convert waste into bioelectricity and chemicals.

Jul 24, 2013
TWiM #59: Are viruses part of our immune system?
01:24:55

Vincent and Michael discuss the finding that bacteriophage might be part of the mucosal antimicrobial defense system.

Jul 10, 2013
TWiM #58: The brain microbiome?
01:21:33

Vincent, Elio and Michael review how underground mycelial networks carry signals that warn neighboring plants of aphid attack, and the presence of bacteria in the human brain.


Jun 20, 2013
TWiM #57: Updating the human gut microbiome to degrade seaweed
58:34

Vincent, Elio and Michael discuss fungi that use pheromones to trap nematodes, and how genes obtained from marine bacteria help gut bacteria degrade algal carbohydrates. 

Jun 05, 2013
TWiM #56: Live at ASM in Denver
01:42:04

Vincent, Elio and Michael recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Andrew, Ferric, Suzanne, and Michelle about their research on a phage system for evading innate immunity, retractions of research papers, bacterial infections of the eye, and cytoplasmic defenses against intracellular bacteria.

This episode was filmed live at ASM GM 2013 in Denver, CO. Visit www.microbeworld.org/asmlive to watch the full video archive of this episode as well as all the videos recorded during GM. 

May 24, 2013
TWiM #55: In the copper room
01:25:00

Vincent, Elio and Michael discuss the finding that copper surfaces reduce microbial burden and hospital-acquired infections in the intensive care unit.

Apr 24, 2013
TWiM #54: Dueling injectors and the microgenderome
01:12:36

Vincent, Elio, and Michael review how sex-dependent differences in the mouse microbiome regulate type I diabetes, and counterattack among bacteria.

Apr 10, 2013
TWiM #53: Live in Manchester
01:00:38

Vincent, Laura, David, Kalin and Paul get together at the Society for General Microbiology meeting in Manchester, England to talk about next-generation approaches to antimicrobial therapy.

Mar 29, 2013
TWiM #52: Clinical microbiology with Ellen Jo Baron
01:00:27
Vincent and Michael meet up with Ellen Jo Baron to talk about working in a clinical microbiology laboratory.
Mar 11, 2013
TWiM #51: Cave science with Hazel Barton
01:18:41

Vincent, Michael, and Elio meet up with Hazel Barton to talk about cave microbiology.

Feb 27, 2013
TWiM #50: These things aren’t even bacteria!
01:03:59

Vincent, Michael, and Stanley review the scientific career of Carl Woese.

Jan 30, 2013
TWiM #49: Grape-like Clusters
01:13:43

Vincent, Michael, and Elio discuss the HIV co-receptor CCR5 as a receptor for S. aureus leukotoxin ED, and the vineyard yeast microbiome.


Jan 16, 2013
TWiM #48: It’s all about direction
01:16:18

Vincent, Michael, and Jo discuss how subtle gender bias of science faculty favors male students, and the relationship of invasive infection and antibody orientation at bacterial surfaces.


Jan 03, 2013
TWiM #47: Resistance on the surface
01:10:56

Horizontal transfer of antibiotic resistance genes on metal surfaces, and using bacteriophage to reverse antibiotic resistance.

Dec 19, 2012
TWiM #46: Spore!
01:09:33

Vincent, Michael, and Elio meet up with Jonathan Dworkin to discuss how bacteria form spores and how they return to vegetative growth.

Dec 05, 2012
TWiM #45: Secreted nucleic acids RIG a STING
01:11:53

Vincent, Michael, Elio review innate immune sensing of Listeria secreted bacterial nucleic acids, and how Wolbachia enhances egg production in Drosophila.

Nov 21, 2012
TWiM #44: Phage interruptus
01:06:08

Vincent, Michael, Elio discuss the role of prophage excision in exit of Listeria from the phagosome, and analysis of bacterial communities in saliva.

Oct 24, 2012
TWiM #43: Bacterial caveolae and zapping acne with phages
01:19:46

Vincent, Michael, Elio review formation of caveolae in a bacterium, and the limited genetic diversity and broad killing activity of P. acnes bacteriophages.

Oct 10, 2012
TWiM #42: Staphylococcus, a three-star pathogen
01:11:42

Vincent, Michael, Elio, and Joe review highlights of the 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in Lyon, France.

Sep 26, 2012
TWiM #41: ICAAC live in San Francisco
01:43:08

Vincent and Michael travel to San Francisco for the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), where they meet with Bill, John, and Victor to discuss tuberculosis, monitoring infectious disease outbreaks with online data, and outside-the-box approaches to antibacterial therapy.


Sep 13, 2012
TWiM #40: A mecca for microbiology
01:01:59

**MicrobeWorld app users, click the "e" symbol in the bottom right corner of this description to watch a bonus video version of this episode!**

Vincent and Stanley meet with Waclaw Szybalski and John Kirby at Cold Spring Harbor Laboratory on the occasion of its designation as a Milestones in Microbiology site. They reminisce about how the well known laboratory has advanced the science and teaching of microbiology, and discuss John’s work on the soil dwelling, predatory myxobacteria.

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This video is also available for free at www.microbeworld.org in the TWiM section, epsiode #40.


Aug 29, 2012
TWiM #39: What Darwin never knew
01:15:30

Vincent, Michael, and Elio reviews chapters from Microbes and Evolution, a collection of short, personal essays by microbiologists.


Aug 15, 2012
TWiM #38: The sound of whooping cough
01:10:52

Vincent, Jo, Michael, and Elio review an outbreak of pertussis in Washington, and how culturing can reveal rare members of the soil biosphere.

Aug 02, 2012
TWiM #37: Microbial Jekyll and Hyde
01:17:43

Vincent, Jo, Michael, and Elio discuss two examples of dynamic microbial symbioses that switch between mutualistic and pathogenic states.

Jul 18, 2012
TWiM #36: Domesticating a pathogen
01:20:24

Vincent, Michael, and Elio explore the origin of Mycoplasma pathogens of ruminants, and share their thoughts on the recent ASM General Meeting.

Jul 04, 2012
TWiM #35: Ohne hauch
01:09:58

Vincent, Michael, and Elio review necrotizing fasciitis, and a link between surface remodeling in gram-positive and gram-negative bacteria.

Jun 21, 2012
TWiM #34: Doing the DISCO with Emiliania
01:08:50

Hosts: Vincent RacanielloMichael Schmidtand Elio Schaechter

Vincent, Michael, and Elio discuss changing populations of Emiliania huxleyi and their viruses in the North and Black Seas.

Right click to download TWiM #34 (50 MB .mp3, 69 minutes).

Links for this episode:

Jun 04, 2012
TWiM #33: Tuning the immune organ
01:08:26

Vincent, Michael, and Ivo review the requirement for segmented, filamentous bacteria for the induction of a specific type of helper T cell in the gut.

Links for this episode:

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv , 

May 16, 2012
TWiM #32: Not the shadow biosphere
01:06:55

Rosie Redfield talks about her evidence that a bacterium cannot grow on arsenic instead of phosphorus. 

May 02, 2012
TWiM 31: Screen door on a submarine
01:15:09

Hosts: Vincent RacanielloJo Handelsmanand Michael Schmidt

Vincent, Jo, and Michael discuss an archetypal protein transport system in bacterial outer membranes, and evidence that gut microbial enterotypes might not fall into defined groups.

Links for this episode:

Apr 18, 2012
TWiM #30: Unraveling melioidosis and insulin resistance
01:10:04

On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.

Apr 04, 2012
TWiM #29: Death and an iron-loaded spike
01:02:48

On episode #29 of the podcast, Vincent and Stanley review how a phage pierces the cell membrane with an iron-loaded spike, and two programmed cell death systems in E. coli.

Mar 21, 2012
TWiM #28: Not unorganized bags of enzymes
01:17:13

Vincent, Michael, and Elio review how competition within a host drives virulence of Streptococcus pneumoniae, and the expanding universe of the bacterial cytoskeleton.

Mar 07, 2012
TWiM #27: An inflamed gut is good for Salmonella
01:14:31

Vincent, Elio, and Michael review how inflammation allows Salmonella to compete with fermenting gut microbes, and a riboswitch in bacterial and Archeal species that is triggered by fluoride.

Feb 22, 2012
TWiM #26: Suum cuique
01:15:05

Vincent, Elio, and Michael discuss the finding of Sutterella species in the gut of autistic children, and methods for cultivating oral bacteria. 

Feb 08, 2012
TWiM #25: Magnetotactic bacteria and totally drug resistant TB
01:16:55

On episode #25 of the podcast, Vincent, Elio, and Michael review bacteria that use the earth’s magnetic field for navigation, and identification of totally drug resistant Mycobacterium tuberculosis.

Jan 25, 2012
TWiM #24: This year in microbiology
01:19:23

Vincent, Michael, and Cliff review ten compelling microbiology stories from 2011.

Jan 11, 2012
TWiM #23: Fighting antibiotics with toxic gas and starvation
01:16:05

Vincent, Jo, Elio, and Michael explain how a swarming bacterium helps disperse a non-motile fungus, and bacterial antibiotic tolerance mediated by hydrogen sulfide and starvation responses.

Dec 28, 2011
TWiM #22: Microbiology 911
01:38:25

Vincent and Michael speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about microbial infections encountered in the emergency room.

Dec 14, 2011
TWiM #21: Symbiotic margheritas
01:08:29

Vincent and Elio discuss ancient symbiosis between Alphaproteobacteria and catenulid flatworms, and a toxin from Helicobacter pylori that engages the mitochondrial fission machinery to induce host cell death.

Nov 30, 2011
TWiM #20: Facebook for bacteria
01:07:51

On episode #20 of the podcast This Week in MicrobiologyVincent, Michael, and Elio follow up on the outbreaks of E. coli in Germany and cholera in Haiti, then discuss genes that confer self-identity to Proteus mirabilis.

Nov 16, 2011
TWiM #19: Your microbiome is what you eat
59:19

Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes.

Nov 02, 2011
TWiM #18: Escherichia coli K-12, an emerging pathogen?
01:14:05

Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City.

Oct 19, 2011
TWiM #17: Debugging endosymbiosis
01:10:31

Vincent, Michael, and Elio focus on endosymbiosis: the rapid spread of Ricekttsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs.

Oct 05, 2011
TWiM #16: ICAAC Live
01:29:14

On episode #16 of the podcast This Week in MicrobiologyVincentMichaelArturoStuart, and David converse about antimicrobial resistance and why most fungi do not cause disease at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

Sep 22, 2011
TWiM #15: Microbial long distance relationships
58:58

On episode #15 of the podcast This Week in Microbiology, Vincent, Michael and Jo review the number of species on Earth, evidence that the 2010 Haitian cholera outbreak originated in Nepal, and how gut microbiota influence the immune response to influenza virus infection of the lung. 

Sep 07, 2011
TWiM #14: Vomocytosis and microbial transistors
01:07:48

On episode #14 of the podcast This Week in MicrobiologyStanley, Margaret, Michael and Elio review how the fungus Cryptococcus escapes from macrophages, and electrical conductivity in nanowires formed by the bacterium Geobacter.

Aug 24, 2011
TWiM #13: Probiotics and inflammasomes: Telling good bacteria from the bad
57:44

On episode #13 of the podcast This Week in Microbiology, Stanley, Jo, Michael and Elio discuss how colonic microbial ecology and risk for colitis are regulated by an inflammasome, and amelioration of intestinal inflammation in mice by delivery of a probiotic-derived soluble protein to the colon.

Aug 10, 2011
TWiM #12: Photothermal nanoblades and genome engineering
01:15:23

Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli.

Jul 27, 2011
TWiM #11: Chickens, antibiotics, and asthma
01:12:40

Vincent, Margaret, Michael and Elio review the presence of extended spectrum beta-lactamase genes in chicken meat and in humans, and a beneficial effect of Helicobacter pylori colonization on the development of allergen-induced asthma.

Jul 13, 2011
TWiM #10: A symbiotic cloaking device
01:08:07

On episode #10 of the podcast This Week in Microbiology, Vincent, Margaret, Elio, Michael and Dickson discuss the symbiosis between the Hawaiian bobtail squid and the luminous, gram-negative bacterium Vibrio fischeri.

Jun 29, 2011
TWiM #9: Bean sprouts and E. coli O104:H4
01:16:35

Vincent, Michael, and Cliff review the outbreak of bloody diarrhea and hemolytic uremic syndrome in Germany caused by Shiga toxin-producing Escherichia coli O104:H4.

Jun 15, 2011
TWiM # 8: Live in NOLA
01:26:21

Vincent, Michael, and Stanley recorded TWiM #8 live at the 2011 ASM General Meeting in New Orleans, with guests Andreas Baümler, Nicole Dubilier, and Paul Rainey. They spoke about how pathogens benefit from disease, symbioses between chemosynthetic bacteria and marine invertebrates, and repetitive sequences in bacteria.

Jun 01, 2011
TWiM #7: Cycles of life and death, light and dark
01:04:09

Vincent, Cliff, Elio, Margaret, and Michael discuss programmed cell death in E. coli, and the daily synthesis and degradation of enzymes needed for photosynthesis and nitrogen fixation by cyanobacteria.

May 18, 2011
TWiM #6: Antibacterial therapy with bacteriophage: Reality or fiction?
01:22:11

Vincent, Cliff, Michael and Elio review the use of bacteriophages to manage infections, and the presence of antibiotic resistance genes in the bacteriophage from urban sewage and river water.

May 04, 2011
TWiM #5: Mercury-methylating Desulfovibrio and antimicrobial nanoparticles
01:15:51

Vincent, Ron, Cliff, and Michael discuss the genome sequence of a mercury-methylating bacterium and the antimicrobial effects of nanoparticles.

Apr 20, 2011
TWiM #4: Cantaloupes and Salmonella gastroenteritis
01:14:45

Vincent, Cliff, Margaret, and Michael review foodborne bacterial illness in the context of outbreaks associated with cantaloupes and Lebanon bologna.

Apr 06, 2011
TWiM #3: Anthrax, genomics and the FBI inquiry
01:00:27

Vincent, Jo, Cliff, and Ron explore the genome analysis done in support of the Amerithrax investigation, and an insecticidal enterotoxin-deficient mutant of Bacillus thurigiensis.

Mar 23, 2011
TWiM #2: The plague, microbial virulence and the gut microbiome
01:15:43

Vincent, Cliff, and Michael review a fatal laboratory acquired Yersinia pestis infection, and how gut bacteria control body weight and metabolic activity.

Mar 09, 2011
TWiM #1: Neisseria LINEs up
01:03:23

On episode #1 of the podcast This Week in Microbiology, Vincent, Cliff, Michael, and Stan discuss transfer of DNA from a human host to a bacterial pathogen, and the ability of dry copper to kill bacteria on contact.

Feb 23, 2011