More and more people are re-training rather than retiring as they age. Reinvention is the preferred option for some of today's boomers, who are enjoying good health and vitality.  Not only are older people sharing the wisdom of their years with younger generations, many are discovering that they have the energy and enthusiasm to take on an entirely new career.  Katie Waldegrave is the co-founder of Now Teach, a UK-based charity which promotes the employment of older people as teachers.  Katie is a vocal campaigner against ageism, which she says can start at a very young age and can even impact how long someone lives.  In this interview, she explains the how Now Teach is helping people realize their dream to start again, go back to college and acquire the skills needed to launch a new chapter in the classroom - and their lives.

Listening options: Apple Podcasts | Audible | Stitcher | Tunein | Spotify | Pandora Podcasts | Google Podcasts | BuyMeACoffee
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This episode was sponsored by Vitality Pro Longevity Supplements, here to offer the latest products in longevity science focused on improving and supporting your health as you age. LLAMA podcast listeners can receive a 5% discount on its products. Use the code LLAMA at checkout.
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DISCOUNTS

▸ Time-line is offering LLAMA podcast listeners a 5% discount on its Mitopure products - Mitopure Powder, Softgels and Mitopure + Protein. Mitopure supports improvements in mitochondrial function and muscle strength. Use the code LLAMA at checkout.  | Learn more about the science here

▸ DoNotAge is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. Use the use code LLAMA for purchases at DoNotAge.org | Health queries can be answered by emailing: hello@donotage.org | Learn more about NoNotAge here

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When Jatin Chaudhary set his sights on climbing the world's highest mountain, he knew he had to optimize his body's ability to operate in extreme conditions. The 43-year-old software development manager from India was aware that his chances of scaling Mt. Everest were diminishing every year and that he would benefit from the physical endurance abilities of a younger man. He dived into the data and investigated why Sherpas can perform at superhuman levels at altitude. He concluded that it was their ability to efficiently use oxygen in their mitochondria, while in a hypoxic environment, such as the heights of Everest where there is less oxygen in the air. It led Jatin to learn more about the gut metabolite Urolithin A (UA) and its role in maintaining healthy mitochondria. 

In this LLAMA podcast interview he explains why he believes supplementation with Mitopure, a proprietary highly pure form of UA, helped fuel his body to scale the highest peak on earth. He also discusses the wider benefits, for an aging population, of maximal mitochondrial health.

This episode is produced in association with the Swiss life science company, Amazentis, which is pioneering cutting edge, clinically validated cellular - nutrition, under its Timeline brand.

Photos: Courtesy Jatin Chaudhary

DISCOUNTS

▸ Time-line is offering LLAMA podcast listeners a 5% discount on its Mitopure products - Mitopure Powder, Softgels and Mitopure + Protein. Mitopure supports improvements in mitochondrial function and muscle strength. Use the code LLAMA at checkout

▸ DoNotAge is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. Use the use code LLAMA for purchases at DoNotAge.org
Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Do you want to live forever? Or do you prefer to focus on living for as long as possible while enjoying the best of health? Lifetime aspirations come in many forms and are often merged together - or confused - under the banner of human longevity. Some are more realistic than others.

In his new book, The Price of Immortality: The Race to Live Forever, the British journalist, Peter Ward, teases apart the many interventions being touted as possible 'cures' for aging or tools to help us live on and on.  He explores the work of "tech visionaries, scam artists, pseudo scientists and religious fanatics."  In this LLAMA podcast interview, Peter offers a dispassionate view on what we are to believe and whether any of it should be taken seriously.

Listening options: Apple Podcasts | You Tube | Audible | Stitcher | Tunein | Spotify | Pandora Podcasts | Google Podcasts

Photo credit: Seren Hughes

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Dr. John Whyte is the Chief Medical Officer at WebMD.  He is on a mission to share accurate health information in a world where finding reliable medical advice can be challenging.

My Day | My Life is a bite-sized supplement to the Live Long and Master Aging podcast.

We explore the lives of people who have, in one way or another, mastered the art of aging. Whether it be through diet, exercise, mindfulness, spirituality, nutraceutical interventions, social connections, generosity or fulfilling careers, we discover the essential elements to living life with purpose, and perhaps, longevity. 

Connect with John Whyte:  Bio | WebMD | Book: Take Control of Your Cancer Risk
Listening options:
Apple Podcasts, Audible, Stitcher,
YouTube, Tunein, Spotify
Pandora Podcasts, Google Podcasts

Read a transcript at the LLAMA podcast website
Related episode: Covid's Silver Lining?

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The popularity of fasting has surged in recent years, although there are myriad approaches to restricting food intake to promote good health.  One system, known as ProLon, involves mimicking the effects of fasting, by allowing small meals to be consumed during the diet.  LLAMA host Peter Bowes has followed the progress of this fasting mimicking diet (FMD) ever since he took part in a clinical trial, in 2013, to explore the regime's feasibility and safety.  In this interview Dr. William Hsu, Chief Medical Officer with L-Nutra, the company that markets the diet, explains the latest science behind periodic fasting nutrition and the differences between the various protocols that are often labeled 'intermittent fasting.'

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Could eating algae be the secret weapon many of us have been searching for in the pursuit of longevity?  The microscopic form of life is consumed as part of a balanced diet is in some parts of the world, but it is also being hailed as a superfood that could help us age better. Of course there is nothing new about algae, which are photosynthetic microorganisms that live in water and grow hydroponically, that is, without soil. The common image is of an icky green film on ponds or areas of stagnant water, but algae grown specifically for consumption, are a potent source of protein and other essential nutrients. It has detoxifying qualities and its regular consumption is linked to a range of benefits including cell health and immune support. In this episode we meet Catharine Arnston, the founder and CEO of ENERGYbits, which makes algae tablets or “bits of whole food". 

Catharine is kindly offering LLAMA podcast listeners a 20 percent discount on EnergyBits products so that you can try algae for yourself. Just use the code LLAMA at EnergyBits.com

Affiliation disclosure: This podcast receives a small commission when you use the code LLAMA for purchases at EnergyBits.com - it helps to cover production costs and ensures that our interviews remain free for all to listen. 

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Nichola Conlon is a molecular biologist and the co-founder of the UK-based nutraceutical company Nuchido Laboratories. 

In this episode Nichola tells us about her love of intense exercise;  the power of fasting; a career that explores drugs that could slow our rate of cellular aging and her passion for explaining science so that everyone can benefit.  She also shares her lifestyle hacks and secrets for a good night's sleep.

My Day | My Life is a Sunday supplement to the Live Long and Master Aging podcast.

We explore the lives of people who have, in one way or another, mastered the art of aging. Whether it be through diet, exercise, mindfulness, spirituality, nutraceutical interventions, social connections, generosity or fulfilling careers, we discover the essential elements to living life with purpose, and perhaps, longevity. 

Read a transcript at the LLAMA podcast website
Related episode: Stimulating the body to repair itself 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Make sure you're getting your daily dose of fish oil.  It is one of the basic rules of nutrition and there is no argument that omega-3 fatty acids are very important for our health. But those fishy burps are irksome. The science behind - and our understanding of omega-3 oils - has come a long way. In today's episode we're going to explore how nano-dispersion technology is being used to fuel our bodies with a new smoothie, EO3 (Enhanced Omega-3), without the downside of unpleasant belching. In collaboration with EO3, LLAMA brought together the company's founder, Janne Karin Sande, who's based on Oslo, Norway, and Prof. Stuart Phillips, director of the Physical Activity Centre of Excellence (PACE) at McMaster University, in Ontario, Canada, to discuss the drink, which contains Norwegian cod liver oil and protein.

This episode is brought to you in association with EO3, the ready to drink product, made with fish oil and protein,  designed to help athletes train faster and harder with optimum recovery. Backed by science EO3 is a complete nutritional solution for cognitive and physical benefits. A better way to get the Omega 3 your body needs.

Prof. Phillips sits on the scientific advisory board for EO3.

Recorded: June 6, 2022 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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What if we could stop time and preserve the biological potential of our younger selves? It is the goal of Forever Labs,  a US company that stores stem cells for possible use in later life, to combat age-related disease and, perhaps, aging itself. The company collects and cryo-preserves stem cells so they can be used in future health treatments and therapies, should medical advances allow it. In this interview Steven Clausnitzer, who founded the company in 2015, explains his vision that illnesses occurring in the years to come, could be treated, or even prevented, through the use of stem cells that were put into storage during healthier times. 

Recorded: March 15, 2022 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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An hour-long walk, before breakfast, is my favorite daily habit. It is a routine that I rarely miss and one which I credit for much of my current health and vitality. For all the latest diet, exercise and supplementation interventions, the simple act of putting one foot in front of the other is, for me, a hugely rewarding lifestyle trail. The benefits of walking are widely documented although the motivation needed to develop a regular practice can be elusive. Dave Paul, an American radio host currently living in the state of South Carolina, is on a mission to promote the longevity enhancing habit through his podcast and blog, Walking is Fitness. With engaging monologues, recording during his morning walk, Dave shares his daily adventures with an audience that he says are "doing a hard thing," but hopefully reaping the physical and mental rewards of a commitment to fitness. In this LLAMA podcast interview Dave explains how his zest for life has evolved into a passion for helping others stay accountable to their daily fitness regimes.

Recorded: March 2, 2022 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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We are what we eat.  So goes the proverbial saying.  But to what extent does the food on our plate determine the quality of our health now and for the rest of our lives?  Marie Ruggles is a clinical nutritionist and the author of Optimize Your Immune System: Create Health and Resilience with a Kitchen Pharmacy. In this LLAMA podcast interview we explore what it means to use the kitchen pantry to promote robust health. From whole foods to superfoods, supplements to sunlight, Marie shares natural wellness strategies and practical options for vibrant longevity.

Interview recorded: February 16, 2022 | Read a transcript at the LLAMA podcast website.

Photo: Susan Elise Shiebler Photography©

This episode is brought to you in association with Clinique La Prairie. The award winning spa clinic and pioneering health and wellness destination nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Every now and then we find a kindred spirit in life. In the field of longevity research, Nick Engerer, PhD, lives and breathes the healthy aging aspirations embodied by the LLAMA podcast.

The creator of Longevity Blog is on a mission to optimize his wellbeing through self-experimentation and science-based interventions. Crucially, he is also driven to share his knowledge to help everyone make lifestyle decisions that promote good health and vitality.

In this interview Nick explains his real-world goal of nurturing his longevity through a data-driven analysis of the latest research. He also discusses the power of exercise, the flexibility of dietary interventions and his belief that longevity breakthroughs should be accessible to everyone.

This episode is brought to you by Longevity Blog, where Nick Engerer simplifies complex topics to help you build a personalized and affordable approach to wellness through self-experimentation. Find Longevity Blog at nickengerer.org/llama and join Nick in your shared quest for maximum healthspan.

Recorded: February 24, 2022 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Beauty, radiant health and the human body and have been inexorably linked.  But to what extent do modern-day, beauty-related practices, enhance our well-being, or even our longevity?  Early in life, Nadine Artemis became fascinated by the intersecting worlds of beauty, essential oils and a desire to live a long healthy life.  She specializes in aromachology, the study of odors and the way they influence human behavior.  Based in Ontario, Canada the creator of  the health and beauty shop, Living Libations, is also a prolific writer, on topics ranging from organic beauty products to holistic dental care. In this LLAMA podcast interview, with Peter Bowes, Nadine discusses her philosophy; her relatively simple approach to personal care and her desire to educate people about what she calls renegade beauty. She also explains why she believes that "every health decision really is a beauty decision, and every beauty decision must be a health decision."

Recorded: March 29, 2022 | Read a transcript and show notes at the LLAMA podcast website.

This episode is brought to you in association with Clinique La Prairie. The award winning spa clinic and pioneering health and wellness destination nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

Support the show

Alan Graves is the CEO of Do Not Age, a UK-based longevity research company and provider of products, such as nicotinamide mononucleotide (NMN), for healthy aging. He emails from bed, eats curated plant-based meals and is on a mission to "democratize" wellbeing.

My Day | My Life is a Sunday supplement to the Live Long and Master Aging podcast.

We explore the lives of people who have, in one way or another, mastered the art of aging. Whether it be through diet, exercise, mindfulness, spirituality, nutraceutical interventions, social connections, generosity or fulfilling careers, we discover the essential elements to living life with purpose, and perhaps, longevity. 

Read a transcript at the LLAMA podcast website

Related episode:  Mission to extend healthy lifespan 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

What happens when a devoted meat-eater spends an hour in conversation with a fellow podcaster, who lives by a plant-based diet?  In this episode of the LLAMA podcast, I meet Dr. Greg Dennis, a family practice physician from Oklahoma City, who also podcasts about health and fitness.  We quiz each other about our longevity-focussed lifestyles - highlighting the significant differences and similarities in our regimes.   Dr. Dennis explains the action he took when he realized that his patients were not getting any healthier, under the traditional "standard of care," and how it led to his weekly podcast, Fit Rx.  We also share our longevity goals and discuss the challenges posed by conflicting advice on how to live a healthy life. 

Recorded: Dec 13, 2021 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

Support the show

This is our Sunday supplement to the Live Long and Master Aging podcast.

My Day | My Life explores the lives of people who have, in one way or another, mastered the art of aging. Whether it be through diet, exercise, mindfulness, spirituality, nutraceutical interventions, social connections, generosity or fulfilling careers, we discover the essential elements to living life with purpose, and perhaps, longevity. 

Sandra Feaster is a registered nurse and health coach.  Now retired she is enjoying a new lease on life - busier than ever, but without some of the pressures of working life.  

Read a transcript at the LLAMA podcast website
Related: Retire, pivot or die - LLAMA podcast interview, April 28, 2019

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

This is our Sunday supplement to the Live Long and Master Aging podcast.

My Day | My Life explores the lives of people who have, in one way or another, mastered the art of aging. Whether it be through diet, exercise, mindfulness, spirituality, nutraceutical interventions, social connections, generosity or fulfilling careers, we discover the essential elements to living life with purpose, and perhaps, longevity. 

Andrew G. Marshall is a marital therapist, writer and host of the The Meaningful Life podcast.  Currently living in Berlin, he is former broadcaster and author of the book, I Love You, But I'm Not In Love With You.

Read a transcript at the LLAMA podcast website
Related:  Aging in a meaningful way - LLAMA podcast interview, February 16, 2022

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

How many times have you turned to a search engine to diagnose your latest ache and pain? Perhaps you visit the doctor and leave the surgery confused and befuddled? Finding and implementing accurate health information - especially preventative measures - can be extremely challenging. It's hard to know what to believe online and some medical professionals are not known for their communication skills. In this LLAMA podcast episode Dr. John Whyte, Chief Medical Officer at WebMD, explains the business of sharing reliable advice.  In a world where information travels fast,  how do we navigate the myriad sources and figure out the best path forward.  Dr. Whyte, author of Take Control of Your Cancer Risk, also discusses his growing appreciation of gratitude and the power of purpose, as tools to prevent disease and enjoy optimum health.

Recorded: Dec 6, 2021 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

Support the show

Carlee Hayes is the lead dietician at NutriSense, a metabolic health company that uses the latest technology to help people continuously track their glucose levels to live a healthier life.

My Day | My Life explores the lives of people who have, in one way or another, mastered the art of aging. Whether it be through diet, exercise, mindfulness, spirituality, nutraceutical interventions, social connections, generosity or fulfilling careers, we discover the essential elements to living life with purpose, and perhaps, longevity. 

Read a transcript at the LLAMA podcast website
Related:  Why continuously monitor our glucose? - LLAMA podcast interview, October 5, 2021

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Welcome to our new weekend supplement to the Live Long and Master aging podcast. To mark LLAMA's fifth birthday this week, we're launching a series of short interviews that delve into daily routines, lifestyle hacks and longevity-driven habits.

My Day | My Life explores the lives of people who have, in one way or another, mastered the art of aging. Whether it be through diet, exercise, mindfulness, spirituality, nutraceutical interventions, social connections, generosity or fulfilling careers, we discover the essential elements to living life with purpose, and perhaps, longevity. 

Chip Conley is hotelier, writer, former executive for Airbnb and founder of the Modern Elder Academy, a self-styled school for midlife wisdom.

Read a transcript at the LLAMA podcast website
Related: Chip Conley: Wisdom, Curiosity and the Modern Elder - LLAMA podcast interview, January 8, 2021

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There is a plethora of science-backed information about how to optimize our health and wellbeing. The challenge, for most of us, is how to filter it and then apply the latest knowledge and innovations to our own lives.  There is undoubtedly a future in personalized medicine and the use of artificial intelligence, to guide our lifestyle decisions. InsideTracker is a health platform that curates peer-reviewed science and combines it with cutting edge technology, to provide insights for its users.  The goal is to make it easier to reach informed decisions about how best to live our lives.  Gil Blander, Phd., an MIT researcher in nutrition and aging, founded InsideTracker in 2009.  In this LLAMA podcast interview, he explains its mission to provide actionable, evidence-backed recommendations to improve health and wellness.

Interview recorded: November 4, 2021 | Read a transcript at the LLAMA podcast website.

This episode is brought to you in association with Clinique La Prairie. The award winning spa clinic and pioneering health and wellness destination nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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What is it about life that makes it worth living? Sure, living a long time with good health and vitality is an aspirational goal, but do you know how to age in a meaningful way? In fact, what is it about living that gives it value and substance? Are we able to mine the wisdom of our years to enhance life's experiences as we grow older? Andrew G. Marshall is marital therapist, a prolific author of books and host of the podcast, The Meaningful Life. In this LLAMA podcast conversation, Andrew, who is based in Berlin, discusses his longtime search for answers to these vexing questions.

Interview recorded: November 24, 2021 | Read a transcript at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Aging with finesse sounds infinitely more desirable than the humdrum process of simply getting older. The language we use in describing the aging process is all important. Perhaps even more important is having a plan, as we age. Even though we "don't feel that old" there is an inevitability about the passing years - despite the latest science-backed interventions that may help us slow down the process. 

Clinical psychologist, Dr. Mary Flett, has spent much of her career analyzing the way we value ourselves as we grow older, how we connect with others as we age, and the skills we need to navigate the process with grace. There are, she says, five "pillars of aging," which include creating a legacy of values, staying engaged, adaptation, spirituality and emotional economics. 

In this LLAMA podcast interview Dr. Flett, who is based in Sonoma, California, discusses the complex, nuanced journey that is aging, and challenges media-driven notions about human longevity. 

Interview recorded: October 20, 2021 | Read a transcript at the LLAMA podcast website.

This episode is brought to you in association with Clinique La Prairie. The award winning spa clinic and pioneering health and wellness destination nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

Support the show

Muscle endurance can be improved, in older adults, without physical exercise, according to the results of a new clinical trial.  Scientists in the US and Switzerland say their research suggests supplementation with a gut metabolite, known as urolithin A, may counteract age-associated muscle decline.  This is significant as a potential intervention that could slow the onset of frailty in older people, and prolong healthspan.   

The study, sponsored by the Swiss life science company, Amazentis  (also sponsors of this podcast), was conduced at the University of Washington Medical Center and the Fred Hutchinson Cancer Research Center in Seattle. 

It was designed to test the hypothesis that long-term supplementation with Mitopure, a highly pure, synthetic form of urolithin A, would improve mitochondrial function and muscle performance in older adults.   

In this LLAMA podcast interview, the study's principal investigator, Prof. David Marcinek, explains the findings and why he believes they could be especially beneficial for older people who are unable to exercise.  We also delve into the importance of mitochondrial health and why the so-called powerhouses of our cells play such a pivotal role in our ability to thrive and enjoy a long life.

Interview recorded: January 12, 2022 | Read a transcript and show notes at the LLAMA website.

This episode is brought to you in association with Amazentis. A Swiss lifescience company that’s pioneering, cutting edge, clinically validated cellular nutrition under its timeline brand.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There are myriad lifestyle, dietary and exercise interventions that could lead to a longer healthspan and compressed morbidity.  Preventing chronic disease, as we age, is crucial but longevity science is also focused on shorter terms goals, such as staying physically and mentally healthy, today and tomorrow. 

Alan Graves is the CEO of Do Not Age, a UK-based longevity research company , which has the stated mission of extending healthy lifespan for as many people as possible. In this LLAMA podcast, Alan explains why he promotes a combination of lifestyle interventions, which are free to implement, and targeted supplementation, to optimize wellbeing.

We delve into one of the hottest topics in the longevity field - the importance of NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in every cell of the body and critical to hundreds of metabolic processes.  Do Not Age's flagship product is NMN, an NAD+ activator, which according to clinical studies, increases insulin sensitivity, reverses mitochondrial dysfunction, and extends lifespan.

Interview recorded: January 6, 2022 | Read a transcript at the LLAMA website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org.  It helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Longevity science has been moving at breakneck speed in recent years, reinforcing the view of some innovators that we are on the cusp of a 200-year lifespan.  Whether it be longevity in a pill, artificial organs or gene therapy to cure diseases, recent breakthroughs suggest many of us already have the tools needed to live much longer and better.  Sergey Young is a longevity investor and visionary with a mission to extend healthy lifespans of at least a billion people. He founded the Longevity Vision Fund to accelerate life extension through technological innovations and recently published his book, The Science and Technology of Growing Young.  In this LLAMA podcast interview, Sergey explores his passion for the emerging science and explains why he believes that optimizing healthspan  - extending our healthy years - is within the reach everyone.  Realistic and pragmatic, Sergey seeks to energize the aging process, celebrating what he calls the "the near horizon of longevity innovations.”

Interview recorded: October 20, 2021 | Read a transcript at the LLAMA website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

As families spend time together over the holidays, who is the happiest person in the room? Grandma, grandad? Growing old gets a bad rap but studies have shown that as people age, they enjoy some of their best days. There is no need to dread your next big birthday, says Katharine Esty, a psychologist and author of Eightysomethings: A Practical Guide to Letting Go, Aging Well, and Finding Unexpected Happiness.

Dr. Esty, at 87, only recently closed her psychotherapy practice, but her life remains full of purpose and meaning, with the publication of her latest book, and a continuing career as a writer. In this LLAMA podcast interview, Katharine explains her upbeat attitude towards life’s final chapter; why new adventures and challenges are possible over eighty and how octogenarians have cracked the secret to happiness.

Savvy and inspiring, she also addresses societal agism and the problem of older people becoming “invisible,” despite the best intentions of their families.

Interview recorded: November 18, 2021 | Read a transcript at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

At LLAMA we reply on our sponsors, affiliates and donors to cover research, production, web hosting and other costs associated with the podcast. If you enjoy and share our mission to discuss new science, promote healthspan and nurture human longevity, a secure donation via PayPal – no matter how small – would be greatly appreciated. It helps to ensure that LLAMA interviews, ideas and inspiration will continue to be available, free of charge – with no paywalls – for anyone to listen.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

Support the show

Older cyclists often try to push the boundaries of athletic prowess as they pursue their life-long, or new-found passion. But is it wise to continue running the engine indefinitely?  Phil Cavell is the author of The Midlife Cyclist and the co-founder of Cyclefit, a UK-based company dedicated to cycling analysis and biomechanics. In this LLAMA podcast interview the veteran club cyclist discuses the art and the science of riding.  He shares a barefoot cyclist's enthusiasm for the sport and explains why attitude, diet, sleep, alcohol consumption - or lack of it - all matter, in the quest to be a successful midlife rider.  He also discusses aging wisdom and the rules of the road that apply to anyone bent on mastering the aging process.

Recorded: October 13, 2021 | Transcribed using Sonix at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Achieving a great age, with good health and vitality, is at the heart of everything we discuss on this podcast.  But who are we, as human beings? What is our purpose and what is the difference between getting old and growing old?  Richard Leider, founder of Inventure – The Purpose Company, is one of America’s preeminent executive-life coaches. He has spent a lifetime trying to better understand the components of life that really matter. His book, Who Do You Want to Be When You Grow Old? dissects the aging path, from adulthood to elderhood. In this LLAMA podcast interview with Peter Bowes, Richard explains why we should feel liberated by the process, rather daunted or hostile, and how purposeful aging - a reason to get up in the morning - is accessible to all. 

Recorded: Sept 27, 2021 | Transcribed using Sonix at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

To maintain mental and physical vitality, the status of the most basic building blocks of our bodies is all important.  There has been an explosion in research relating to cellular health and the measures we can take to nurture their wellbeing. Greg Macpherson is a biotechnologist, pharmacist and the author of Harnessing the Nine Hallmarks of Aging: Turning Our Cells Into Little Pharmaceutical Factories.  But how does that way of thinking apply to our everyday lives?  In this interview with Peter Bowes, Greg explains the significance of recent scientific breakthroughs and why he believes it is realistic for more of us to contemplate life as a centenarian in the coming decades.

Recorded: Aug  31, 2021 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

As we grow older, frailty becomes an issue due to declining muscle strength. For athletes, muscle fatigue can be a huge challenge at any age, but there is scientific evidence that nutritional interventions can slow down or reverse the process. 

The LLAMA podcast has previously covered the science behind muscular health and the potential benefits of Mitopure, a pure form of the metabolite compound Urolithin A. According to clinical studies, it boosts cellular function and improves leg muscle strength in people over the age of 40.  

 In this episode we explore the latest science. Professor Louise Burke, the Chair of Sports Nutrition at the Institute for Health Research, Exercise and Nutrition Research Program, at the Australian Catholic University, is conducting a study with top athletes to evaluate the clinical evidence for Mitopure in a younger and more athletic populations. Will it help improve performance and what are the implications for non-athletes who want to maximize their muscular strength, as part of a healthy aging lifestyle? 

Recorded: October 7, 2021 | Read a transcript  and show notes at the LLAMA podcast website

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Regular exercise is key pillar of healthy longevity. But which activities really make a difference – running, walking, a gym class, yoga, weightlifting? Does it have to involve breaking into a sweat, or ten thousand steps, to do any good?  Some health practitioners have taken to advocating daily movement over traditional exercise. Stefan Zavalin is a Doctor of Physical Therapy and the owner of Love to Move, a company that advises employers on workplace design and ways to promote physical and emotional wellness. In this LLAMA podcast interview, with Peter Bowes, Stefan explains the benefits of a movement mindset and why focusing of vigorous exercise is not always helpful. He says movement is at the core of everything we do, day and night, and should play a bigger role in our lives.  He discusses the benefits of periodic standing over sitting; his commitment to multiple daily walks and a fun approach to keeping the body moving. 

Recorded: Sept 22, 2021 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Wearable technology has evolved at a pace recently, making it possible to better understand how our bodies respond to food and exercise. A continuous glucose monitor (CGM) device provides real-time feedback, tracking blood sugar levels throughout the day and night. LLAMA host Peter Bowes has been wearing a CGM to learn more about my metabolism. It was provided by NutriSense, a US company that uses the latest technology to help its clients optimize their wellbeing. This LLAMA LIVE! conversation is a follow-up to our last episode, with nutritionist Carlee Hayes, to dig deeper into the science behind glucose monitoring. 

The conversation, which took place on October 14th, 2021 at 12 noon PST, published here as a podcast, explores the subject with our Twitter community and features insights from:

• Carlee Hayes, lead dietician at NutriSense @nutrisenseio
• Stefan Zavalin, physical therapist @LoveToMove3

There will be more Twitter Spaces LLAMA LIVE! conversations, featuring a wide range of guests and thought-leaders in the longevity space.  We’re open to suggestions for contributors and topics – and everyone is welcome to take part.  

Follow us @LLAMApodcast and @peterbowes for first news of upcoming conversations. 

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Real-time information about how our bodies respond to food and exercise is transforming preventative healthcare. Wearable technology provides immediate feedback during a workout and can collate and interpret complex data based on our food choices. One of the deepest dives into the inner workings of our metabolism is achieved through continuous glucose monitoring (CGM). Carlee Hayes is the lead dietician at NutriSense, a metabolic health company that uses the latest technology to help its clients optimize their wellbeing through a better understanding of their bodies. In this LLAMA podcast interview, with Peter Bowes, Carlee explains the science behind continuous glucose monitoring and why it provides a valuable insight into our state of health.

Recorded: Sept 14, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Listening options: Apple Podcasts, Audible, Stitcher, Tunein, Spotify, Pandora Podcasts, Google Podcasts

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

It's often the little things that help us most. Enhancing our wellbeing and living better usually starts with baby steps. Small changes - you could call them lifestyle hacks - can make a big difference to both our physical and mental health.

In our latest LLAMA LIVE! conversation, via @TwitterSpaces, we discussed the ways we can kickstart a healthier life by implementing small, progressive changes to the way we live our lives. 

We cover everything from early morning walking, sunlight, and balance as we age, to hot organic cocoa, continuous glucose monitoring and dancing while doing the dishes.

The conversation, published here as a podcast, explores the these ideas with our Twitter community and features insights from host, Peter Bowes and:

• Roy Burstin @roybu - Founder, Nowgevity, a collective of healthspan enthusiasts, citizen scientists, tinkerers, and optimizers @nowgevity
• Dr. Felice Gersh @DrFeliceGersh - Medical Director, Integrative Medical Group of Irvine.

There will be more Twitter Spaces LLAMA LIVE! conversations too, featuring a wide range of guests and thought-leaders in the longevity space.  We’re open to suggestions for contributors and topics – and everyone is welcome to take part.  

Follow us @LLAMApodcast and @peterbowes for first news of upcoming conversations – every Thursday at 1pm Pacific time/4pm ET/9pm BST. 

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Dr. Jonathon Sullivan has spent much of his professional life treating patients on the brink of death. Working at a Level I trauma center he became familiar with medical conditions that claim lives far too early. But emergency medicine also helped the former US marine develop a deeper understanding of the human body and the reasons people get sick as they grow older.

Now, as the owner, head coach and clinical director of Greysteel Strength and Conditioning, Dr. Sullivan focusses on extending heathy life. Based in Farmington Hills, Michigan, Sully, as he is known, practices a unique form of medicine. He calls it the Barbell Prescription - weight lifting, for longevity.

In this LLAMA podcast interview he explains why dumbbells, not drugs, are the best tools to fend off disease and frailty.

Recorded: Sept 7, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Healthspan - what is it and why is it important?

This is our second LLAMA LIVE! - a Twitter Spaces conversation about human longevity. 

Host Peter Bowes chats with Dr. Jonathan Sullivan, owner and Clinical Director, Greysteel Strength and Conditioning

Stefan Zavalin, a doctor of physical therapy and owner of Love to Move, a consulting company which offers advice for environment design and physical wellness in the workplace.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

This is our first LLAMA LIVE! episode - a Twitter Spaces conversation about human longevity, healthspan and lessons learned from Covid-19. 

Dr. Felice Gersh, an integrative medicine specialist, based in Irvine, California, joined Peter Bowes for a live discussion, earlier today. The conversation, published here as a podcast, covers children and Covid, immunity, obesity, inflammation, resilience through exercise and the way ahead, as we emerge from the pandemic. 

There will be more Twitter Spaces LLAMA LIVE! conversations over the coming weeks, featuring a wide range of guests and thought-leaders in the longevity space. We're open to suggestions for contributors and topics - and everyone is welcome to take part. Follow us @LLAMApodcast and @peterbowes for first news of upcoming conversations. 

Connect with Dr. Gersh: Website | Twitter | Instagram

Earlier interviews with Dr. Gersh:

• March 13, 2020 | LISTEN - Dealing with Coronavirus
• December 11, 2018 | LISTEN – Dealing with festive season stress and overwhelm.
• May 21, 2018 | LISTEN – Nurturing the body clock for longevity
• July 4, 2017 | LISTEN – Advocating for a new approach to healthcare

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Mineral deficiencies can have a crippling impact on our everyday health and vitality, as well as long term implications for healthspan.  The food we eat and the environments we live in, play a critical role in maintaining a delicate balance of chemicals that sustain life.  But even the most ideal-sounding diet can fall short of providing an essential mix of minerals.  Barton Scott discovered the hard way, through ill health, that he suffered from chronic deficiencies that were severely impacting his quality of life.  Myriad dietary interventions failed to resolve his issues and prompted Barton to apply his knowledge, as a chemical engineer and nutritionist, to resolving the problem. The solution, he discovered, revolved around the body's ability to absorb mineral particles.  It led to him creating Upgraded Formulas, a company that applies nanotechnology to minerals and assesses which components we need through a hair test.  

In this LLAMA podcast interview Barton explains the background to his company and why he believes that regular testing for heavy metal toxicity and mineral deficiencies is essential to support a healthier, happier, more productive life. 

Recorded: Sept 6, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Upgraded Formulas discount for LLAMA podcast listeners: 

Use Code LLAMA for 10% off - thanks Bart! 

Listening options: Apple Podcasts, Audible, Stitcher, Tunein, Spotify, Pandora Podcasts, Google Podcasts

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Developing a health strategy to navigate the decades ahead can be a daunting task.  In fact, many people focus on their wellbeing only when ill health strikes and an intervention is needed to tackle sickness. Jim LaValle, a California-based clinical pharmacist, health educator and the author of Cracking the Metabolic Code: 9 Keys to Optimal Health, is on a mission to demystify the process.  The founder of Metabolic Code, a health evaluation program that creates a plan of action for people to live and feel better, Jim is a proponent of precision medicine.  In this LLAMA podcast conversation with Peter Bowes, he explains the process of scrunching health data, making sense of lab tests and interpreting biometric information.  He discusses the threat posed by inflammation, the importance of gut health and why an understanding of so-called metabolic roadblocks is crucial.  Jim and Peter also share their thoughts on what it really means to "age with grace.'

Recorded: July 21, 2021 | Read a transcript and show notes at the LLAMA podcast website.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

What if we all had a personal, digital avatar to guide and nurture our lives, as we pursue a long healthspan? The concept, in a world of personalized medicine, could become a reality, according to future-thinker and longevity entrepreneur  Dmitry Kaminskiy.  The London-based investor and co founder of the UK All Party Parliamentary group for Longevity focuses on the intersection of artificial intelligence and the aging process.  His latest book, Biomarkers of Longevity, he explores the way technological advances in longevity have exploded in recent years and how breakthroughs in the science of aging will enhance our lives in the decades come.  In this LLAMA podcast conversation with Peter Bowes, Dmitry explains his vision of the future and why he believes there will soon come a time when we can “freeze” the aging process. 

Recorded: June 29, 2021 | Read a transcript and show notes at the LLAMA podcast website

In this episode we cover:

• Separating reality from the sci-fi image of extreme life extension
• Scientific breakthroughs since 2017 and the explosion in interest in human longevity 
• Defining the pursuit of realistic healthspan over radical life extension
• Measuring the bio markers of aging in the pursuit of an extra ten years 
• Dmitry’s early life and upbringing in Moldova.
• Offering a prize of $1m to the first person to reach the age of 123
• A viral idea to draw attention to the importance of investing in longevity
• Planning for financial longevity and wellness
• What does it mean to freeze the aging process?
• Filtering out hype in the longevity space, especially the extrapolation of finding in mice to humans.
• The intersection between space medicine and longevity research
• The future role of ‘real time’ digital avatars in managing our health and crucial bio markers
• Using technology to adjust health-focused lifestyles based on  geographic location
• Dmitry’s technology-focused lifestyle designed to enhance his longevity.
• The value of walking ten thousand steps per day.  

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.: 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There are some people who just never seem to get any older. Whether it be their appearance or mental attitude, the passage of time eludes them.  How do they do it?   There are myriad explanations;  our genes, physical and dietary lifestyles, mindset and perhaps an element of luck. The truth is that all these factors - and many others - likely play a role is determining our destiny. Jason Elias is the author of The Seven Graces of Ageless Aging:  How to die young as late in life as possible, a collection of stories and longevity lessons based on decades of practice in the fields of Chinese medicine - treating patients with acupuncture and other tenets of eastern medicine.  In this LLAMA podcast conversation, with Peter Bowes, Jason explains his unique recipe for a long, happy life - embracing, as he does, daily walks, ancient remedies and an infectious zest for living.

Recorded: June 25, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

In a world where we are bombarded with health advice, it is easy to feel lost in a sea of unverified information. From dietary supplementation to exercise, we are inundated with suggestions, hard-sell advertisements and sometimes peer pressure, to take up one regime or another. LLAMA’s advice is simple; consult your primary care doctor or healthcare professional if you are considering lifestyle changes that involve a new diet or exercise program.  In this episode, we meet a family physician who has been wrestling with frequently asked questions and evolving medical science for over forty years. Dr. Walt Larimore is  the author of multiple books and articles on healthcare, including the Natural Medicine Handbook: The truth about the Most Effective Herbs, Vitamins and Supplements for Common Conditions.  In this conversation with Peter Bowes, Dr. Larimore, who is based in the US city of Colorado Springs, explains how he sorts fact from fiction; why he says sufferers from some of the most debilitating diseases are being offered false hope; and how simple everyday steps can be taken to promote optimum health without the need for any external interventions. 

Recorded: June 8, 2021 | Read a transcript and show notes at the LLAMA podcast website.

In this interview we cover:

• A family doctor’s introduction to sharing information about natural medicines on TV 
• Why consumers are easy confused by a supplement industry which is unregulated in the US.
• Access to independent quality testing labs to enhance our knowledge about nutritional supplements.  
• A lack of training covering nutrition and supplementation for primary care doctors 
• How to evaluate the effectiveness and safety of natural medicines based on reliable sources, such as Natural Medicines, ConsumerLab.com and LabDoor.com  
• Are we being bamboozled into taking supplements that we don’t need?  What are the alternatives?  
• Simple lifestyle habits like avoiding tobacco, regular movement, a good diet and restful sleep to promote good health. 
• Choosing an evidence based nutrition plan for optimum health. How to filter the available information based on accessibility, cost and nutritional value. 
• Why is a Mediterranean type diet highly-rated as a nutrition plan?
• Finding recipes and exercise programs that involve fun and suit the entire family 
• Incorporating movement into your life, little by little, to nurture the mind and body.  
• The common conditions that lead to enduring ill-health, such as heart disease, hypertension, diseases of the brain, including Alzheimer’s and the scourge of obesity. 
• The advertising industry and false hope for people suffering from dementia. 
• Religious struggle and health challenges.
• Daily, spiritual discipline to promote good health and wellbeing. 

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

If only we could detect all life threatening diseases before symptoms occur and early enough to reverse the course of those conditions.  We are on the cusp of being able to achieve that.  Significant, recent developments, in the field of genomic testing, mean that scientists are able to pinpoint the warning signs for some major degenerative illnesses, in time to make life-saving interventions. In this episode of the LLAMA podcast, we meet Jo Bhakdi, the founder of Quantgene, a Santa Monica based team of researchers - oncologists, clinicians, technologists, data scientists and business innovators  - who're working to change the paradigm of healthcare.  In conversation with Peter Bowes, Jo discusses his startup company’s mission of defeating cancer and extending human lifespan by ten years, within the next decade. He also reflects on the exploding interest and progress in human longevity research, which has seen the field grow, exponentially, in recent years. 

Recorded: May 30, 2021 | Read a transcript and show notes at the LLAMA podcast website

In this interview we cover:

• The mission of Quantgene "to combine deep genomics, cloud and artificial intelligence into a new technology stack" to help detect dangerous diseases like cancer.
• Why the ability to get genomic data points from DNA is an "enormous game changer" in healthcare.
• The merging of mathematics and complex numeric problems with biology and medicine. 
• Quantgene's mission of extending the human lifespan by ten years within the next decade. 
• The business model, cautious investors and taking the technology to the next level
• Taking the tests - what does it involve?
• Understanding how medicine and diagnostic work, plus the value of lifestyle information. 
• What it means to overlay the conventional care system with one based on genomic science, such as Quantgene Serenity.
• What about people who would simply rather not know about the diseases they are predisposed or likely to develop? 
• Tying to convince health systems and governments to embrace new ways to diagnose potential ill health. 
• Adopting a radical philosophy about personal longevity. 
• Leveraging the "natural stuff" to live long and well. 
• Given the current science, what is a realistic, maximum lifespan? 

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.: 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The power of food - plants in particular - to help us optimize our health and potential longevity can not be underestimated. Indeed nature itself is arguably the most powerful tool we have to thwart disease and the ravages of the aging process.  Dr. Nora Khaldi is the founder of Nuritas, a Dublin based biotechnology company that's pursuing a theory that natural foods contain all the molecular tools people need to optimize their health and wellbeing.  Dr. Khaldi has an ambitious goal to make revolutionary discoveries, through the study of plants, that will allow people to live healthier for longer.  In this LLAMA podcast conversation with Peter Bowes she explains the remarkable potential of peptides discovered in the fava bean to supports muscle health in people. She also discusses the astonishing complexity and relevance of wallaby milk to the building blocks of the human body. 

Recorded: April 28, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Approaching life science with a diverse academic background, including pure mathematics.
• Bioinformatics, molecular evolution and comparative genomics. 
• Looking at a human bodies as a system of interactions
• Why do wallabies and their milk matter? 
• The importance of peptides - short strings of amino acids - and where they are found. 
• Harnessing the power of peptides discovered in the fava bean plant  to supports muscle health.
• Exploring the full potential of food and plants through Nuritas and Elio™.
• Translating the positive finding of science to benefit consumer needs.  
• Supplementation, do I really need it? 
• Starting conversations with health providers about precision supplementation. 
• Food as the problem, but also the solution.  
• Creating healthier versions of food without compromising on taste.
• Devising a lifestyle to achieve a good healthspan.
• Living longer but also being sicker for longer. 
• Is living to 120 a realistic goal?   

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Finding the most effective workout and diet regime, with the goal of getting fit and lean, is, for many, the ultimate challenge.  Even elite athletes struggle as they strive to achieve their peak level of performance.  Jon Pearlman, a former #1 singles player for the Harvard tennis team, learned through personal experience that athletic prowess does not come easy.  The two time All-Ivy athlete and ATP-ranked touring professional, had performance setbacks as a young tennis player but he learned through his struggles and now advises others on the best way to build a healthy, lean body for life.  

In this episode of the LLAMA podcast, the author of The Lean Body Manual and co-founder of the fitness app, Mission Lean, discusses his mission to help people transform their bodies and defy their age. 

In conversation with Peter Bowes, Jon discusses the pros and cons of a 'strength and conditioning' approach to fitness training; explains why he prefers to workout on an empty stomach; and why he believes there's an "inner athlete" just waiting to be discovered in all of us. 

This LLAMA podcast episode is co-produced in association with Mission Lean, the fitness app that offers more than 150 on-demand workouts, specifically designed and curated to get you lean.

Recorded: April 27, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Jon's personal journey to peak physical fitness.
• Experimenting with different workout regimes. 
• Overcoming fitness obstacles by focussing on lean fitness methods.
• Obsession and determination to achieve peak physical fitness and a performance  edge.
• Questioning the value of weightlifting and a 'strength and conditioning' approach to fitness training. 
• The importance of muscle strength for older people.
• Achieving optimum fitness and finding the best workout to make it happen.
• Takeaway lessons from Jon's experience training with the world's top tennis players
• The Lean Body Manual
• Defining the fitness goal - physically and mentally - before setting out to achieve it.     
• Adapting to using an app as a fitness coach.
• Heart-rate zone training and a Mediterranean diet. 
• Lifestyle hacks and how, what and when to eat.  
• The age-old debate about the most important meal of the day.  
• Figuring out an "ideal harmony" between working out and eating. 
• Exercising with an app and developing the right mindset to achieve success. 
• The impact of Covid on at-home workouts 
• Personal longevity aspirations and latching on to the inner athlete.  
• Prolonging healthspan through a commitment to a structured fitness program

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Making exercise a daily routine, from childhood, could be the key to preventing or slowing down some of the diseases of old age. Multiple studies have demonstrated the efficacy of physical activity, in improving cognitive health, throughout the human lifespan. Jenny Etnier is a professor of sport and exercise psychology in the Department of Kinesiology at the University of North Carolina. Working with children and older adults she is an advocate for exercise to nurture the mind and stimulate a healthy brain.  In this LLAMA podcast episode, with Peter Bowes, Dr. Etnier explains the lifetime benefits of physical education in schools; the meaning of mental toughness; and the reason why we should all enjoy a few minutes of "pure joy" every day. 

Recorded: May 4, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Helping children have a more positive youth sport experience
• Taking a lifetime approach to physical activity for all ages, for mental health
• Making exercise a lifetime habit
• The value of physical education in schools. 
• Jenny's exposure to exercise leading to a lifetime of sport and coaching. 
• Parents' priorities and goals for their children and sports. 
• Learning how to self reference for personal joy and improvement. 
• Walking basketball - why not?
• The mental health benefits of physical activity, movement and exercise. 
• How our lives have changed, for the better, during Covid, emphasizing exercise.
• Quantifying the cognitive benefits of physical activity.    
• Mental toughness and the notion that it also applies to how we live our daily lives - time management and stress.  
• Physical activity to delay   the onset of symptoms for people at risk from Alzheimer's.  
• Making a regular commitment  to sport with a partner. 
• Setting aside a few minutes for pure joy every day. 
• Future studies: the timing of a single session of exercise for better memory the next day.

This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

We are all used to feeling younger than our years and occasionally older than our birth date would suggest.  In effect, we have two ages - chronological and biological. Chronological age simply states the number of years that we have been alive, whereas biological age is a measure of how well our bodies are performing, in relation to the rest of the population. 

So how is it determined?  LLAMA host Peter Bowes delved into the science with Elysium Health, which has developed Index, a DNA test that tracks how fast we have been aging, based on our epigenome, which regulates the way genes work. 

In this episode, Peter meets Dr. Morgan Levine, an assistant professor of pathology at Yale School of Medicine and an advisor to Elysium Health. They discuss the background to Index, its use of epigenetic clocks to put a number to our biological age, as well as the test's accuracy and implications for healthy living.

Recorded: April 21, 2021 | Read a transcript and show notes at the LLAMA podcast website. 

Topics covered in this interview include:

• Defining biological age and chronological age. 
• Age as a risk factor for death and disease
• Having an older parent and developing an interest in aging 
• A lack of consensus over what exactly is meant by aging.
• How much of aging can be defined as damage to the body, at a cellular level, as we grow older?
• How do we measure biological age?  
• Genes, genomes and the epigenome.
• Developing systems that determine biological age based on epigenetic clocks.
• Exploring the Index epigenetic, at-home saliva test, to determine biological age.    
• Privacy concerns related to sharing personal medical information.  
• Revealing Peter's biological versus chronological age. What does it mean? 
• Interpreting the test results and taking action based on the findings.
• Does the test reveal information specific to potential medical conditions?
• How do doctors - primary care physicians - respond to the information gleaned from such tests? 
• The paradigm shift from disease treatment to interventions that delay illness. 
• Lifestyle interventions that promote a long, healthy life.  
• The reliability of biological age tests. Do repeat tests over a short space of time generate the same results? 
• To what extent do results vary between young and older people? 
• Lifespan and healthspan aspirations. 

Disclosure: For review purposes, Elysium Health provided Peter Bowes with an Index test kit, free of charge .

This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Some of the world's healthiest people spend little or no time pondering their propensity to live a long life.  They just do it. Their lifestyles are a model for longevity. There is much we can learn from these vibrant populations, in countries such as Italy, India, Japan, and (even) parts of the United States.  In this episode of the LLAMA podcast with Peter Bowes, filmmaker Daniel Kennedy discusses his quest to better understand global food and ancient healing traditions. Daniel's documentary series, Healthy Long Life, is an exploratory journey around the globe and considers the discrepancy between lifespan and healthspan; he asks why, for many people, the final years of life are spent in sickness and pain and shares observations about spirituality, mealtime traditions and chronic diseases. 

Recorded: April 19, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Filming Healthy, Long Life over four years and Daniel's motivation behind the project 
• Lifespan vs healthspan and what it means for our children and grandchildren
• Are chronic diseases pre-determined?  Searching for answers. 
• Deriving inspiration from people with cancer to help others avoid the disease
• Meeting physicians who use plants as medicine, including T. Colin Campbell, the author of the China Project 
• Pinpointing the world's longevity hotspots and learning from ancient healing traditions 
• Fighting illness or promoting health? 
• Plant based diets and the risk of contracting cancer
• Science, spirituality, food and faith 
• The long lives of Seventh Day Adventists from Loma Linda, California
• The idea that "genetics may load the gun but it's diet and lifestyle that pull the trigger."
• The relative benefits of a healthy dietary regime and a life full of physical activity. 
• Is there a French paradox - wine, cheese, butter and good health? 
• Portion size and caloric restriction.

This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The science of aging is so infinitely fascinating that Dr. Sandra Kaufmann decided to immerse herself in the field, as a hobby. A pediatric anesthesiologist from Florida, Dr. Kaufmann, is also an athlete who manages to fit swimming, running and rock climbing around her busy hospital schedule.  Determined to enjoy physical activity for as long as possible, she decided to carry out an extensive review of the scientific literature, to better understand our bodies as we grow old.  She focussed on the mechanisms of aging at a cellular level and set out to sort fact from fiction when it comes to the substances or interventions that might help us age more slowly.  The result is, The Kaufmann Protocol: Why We Age and How to Stop It, a book in which she sets out seven key tenets to maintaining optimum health. In this LLAMA podcast conversation, with Peter Bowes, Dr Kaufmann  explains everything from the importance of mitochondrial health and the maintenance of metabolic pathways, to her live and let live attitude towards eating a donut a day. 

In this interview we cover:

• Setting the bar high to "overcome all aging"
• The most ornate out-of-control hobby anybody can have
• A light-bulb moment having off a cliff. 
• Is it selfish to focus on the science of 'stopping' aging?
• Becoming a human guinea pig to try to figure out why cells age. 
• Nurturing the seven protocols
• Debunking myths - or ideas behind grandma's remedies - about interventions to slow down the aging process
• Junk food, including a donut a day.  Really? 
• Being an exercise junkie
• Biohacking: striving to improve what we are, but is the term realistic? 
• Feeling like a teenager at 52

This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic - and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Embracing science and a holistic approach to living a healthier life, has been a hallmark of the Swiss spa-clinic, Clinique La Prairie (CLP), for the past ninety years. Known for its signature treatment, cellular therapy, the medical center opened in 1931, under the guidance of  Dr Paul Niehans, an early expert in the field. Today, CLP melds cutting edge technology with a mission to help people optimize their healthspan, though advanced clinical and wellness programs. The LLAMA podcast is teaming up with CLP to discuss the big issues surrounding human longevity. In this episode, Peter Bowes is joined by C.E.O. Simone Gibertoni and Medical Director, Dr. Adrian Heini.  In a wide-ranging conversation they cover the clinic's history, scientific developments, including Epigenetic screening, and the future of wellbeing as a priority in the post-Covid world. 

Recorded: April 20, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Clinique La Prairie's 90-year legacy
• The history of a medical spa that melds science and luxury relaxation 
• The scientific gatekeepers monitoring the science behind health and wellness programs 
• Using natural tools to curate a holistic approach to living better and longer
• Developments in genetics and epigenetic tests to reveal predispositions to certain conditions
• Tailored  programs to focus on conditions such as oxidative stress and inflammation
• Plants, herbs and fatty acid profiles
• The lifestyle trails that influence longevity
• Personalized healthy living programs and the four pillars for longevity
• Changing lives and following up to ensure long-term health
• Why there is no "magic pill"
• Mindfulness, meditation and bespoke physical exercise modifications 
• The eye-opening impact of Covid on the business of wellness and the long term implications for healthcare
• The lasting impact of a week's intensive therapies?
• Implementing  long-term health programs though CLP hubs around the world. 
• The importance of lifestyle changes and work/life balance. 
• Morning routines and daily health. 
• Taking the long view and imagining the wellness conversation for decades to come. 

“This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic - and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.”

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The art of growing old, gracefully and purposefully, preferably in rude health, is unique to us all. The journey, with its many twists and turns, involves myriad emotions, adventures and challenges. But Kathleen O'Brien says the process has been somewhat hijacked by society's growing disrespect for the elderly. In her book, Reclaim Your Right To Grow Old, the American writer and broadcaster explores the history of attitudes towards aging and suggests that society's fevered quest for longevity is misguided.  In this LLAMA podcast conversation with Peter Bowes, Kathleen argues that the happiness to be found in aging is being undervalued; that the eccentricities of older people should be celebrated and the joy of smelling the roses more often enjoyed. 

Recorded: April 12, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Kathleen's voice was once very familiar to Americans  - how come? 
• Approaching the "sad ride on the down slope" and discovering a new way to look at aging. 
• Exploring the history of aging and the attitudes of ancient cultures, especially towards 'elders.'
• What the location of graveyards tells us about changing attitudes towards older people and death
• Is 'keep busy, keep active' necessarily a positive message, as people age. 
• The 'reclaim your right to grow' old philosophy
• Embracing the eccentricities aging - being free to be who we want to be. 
• Smell the roses and worry less
• Death anxiety, spirituality and changing attitudes as we age

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There has been "spectacular" progress in recent years in the understanding and treatment of Alzheimer's.  The progressive disease, which is the most common cause of dementia, a late-in-life decline in memory and cognitive ability, afflicts 50 million people around the world. Taking family members and other carers into account, that number increases exponentially.  The condition, for which there is currently no cure,  amounts to a modern day crisis, for all involved. In this episode of the LLAMA podcast, Dr Jason Karlawish, a gerontologist and professor of medicine and medical ethics and senior fellow of the Center for Bioethics at the University of Pennsylvania, says significant gains are being made with therapeutic treatments, but many hurdles remain.  The author of The Problem of Alzheimer's: How Science, Culture and Politics turned a Rare Disease into a Crisis, also argues that Alzheimer's is disease of our identity and a condition that raises fundamental, moral questions about what it means to lead a good life. 

Recorded: March 30, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• The difference between dementia and Alzheimer's disease.
• How can dementia be distinguished from the 'normal course of aging?"
• The work of the Penn Memory Center, with patients and their loved ones. 
• Explaining medicine in the 'real world,' through the stories and experiences of people.
• Why patients and caregivers are the best teachers. 
• Distinguishing between disease and disability. 
• How stigma haunts the lives of people with dementia. 
• Defining Alzheimers as once a rare disease, now a crisis. 
• The "spectacular progress in science," dealing with Alzheimer's. 
• "Living' with Alzheimer's rather than relying on drugs. 
• Why is the risk of demential declining? 
• The crisis of good quality care for Alzheimer's patients in the U.S.
• Regular exercise and a heart healthy diet to maintain good brain health.  Red wine too? 

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Turning fifty can be a wrenching experience for some people.  Others discover that it is their sixtieth birthday that conjures up disturbing emotions. There is no doubt that big birthdays focus the mind on the aging process and what is often described as a midlife crisis.  But should we fear the passage of time?  Lisa Levine is a life coach and the author of Midlife No crisis, an insightful and entertaining exploration of the years that signpost our lives.  In this LLAMA podcast conversation with Peter Bowes, Lisa explains why we should embrace "transformative" periods, instead of dreading them, and how the advancing years can propel us in a "more fulfilling direction," with excitement and optimism. 

Recorded: April 5, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• When does mid-life happen and why is it associated with a crisis for some people.
• Pre-empting a mid-life crisis 
• When the meaning  of life becomes more important that just doing a job. 
• The difference between turning 50 and 60?
• Leaving Hollywood and the entertainment business for a new calling - something deeper with more meaning. 
• Becoming a life coach and "walking the talk." 
• Dealing with health obstacles and fertility issues and discovering alternative therapies. 
• Do men and women face the same mid-life issues? 
• How our backgrounds and life experiences mold our lives and attitudes toward aging. 
• Discovering the perks on midlife, wisdom and putting space between negative thoughts.
• The value of friends and community in dealing with the aging process - knowing that you're not alone. 
• Social media - compare and despair. Avoiding the rabbit holes. 
• The privilege that is aging. 

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Living life to the full, at any age, has been a challenge recently.  To put it mildly.  But if Covid has taught us anything, it is that some of life's simplest pleasures are what make life itself worth living. Therein lies a metaphor for healthy aging.  Physical fitness, social contact and an active mind go a long way towards helping us live longer and better.  They are also central to the ideals of Aging is Cool, a Texas-based company that helps people over fifty stay active and engaged as they age. 

In this LLAMA episode, Aging is Cool co-founder, Amy Temperley, explains why she rails against a modern-day culture rife with ageism and how she hopes to redefine what it means to grow old. 

"Old is a feeling and I don't know that you're old until you decide that you're old," she says.  

In conversation with Peter Bowes, Amy also reveals how life with Covid has opened her eyes to the everyday activities that bring pleasure and purpose to life. 

Recorded: March 22, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Targeting healthy, active aging and coming up with the idea for Aging is Cool
• Realizing that aging can be positive, celebrating a robust zest for life and it is okay to get older.  
• Is there a benchmark for becoming old
• Anti-aging versus finding a sense of purpose in life. 
• Building a company focussed on mind and body training for older adults
• A Mighty Good Time -  a one-stop-shop and mostly virtual resource for adults aged 50+
• Over fifty - is there a mindset change? 
• Reducing social isolation through involvement in a community
• The value of friendship and forging new relationships
• Social interaction post Covid and find new joy-inducing pastimes. How making stuff can be fun. 
• Advocacy for the benefits of a healthy, aging population. 
• Breaking out of Covid, socializing more and multi-generational friendships. 
• Morning rituals that include caring for dogs. 
• Finding those things that make life worth living - "embracing the things you love rather than lamenting what you've lost."

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Cracking the code behind aging has long since fascinated, frustrated and captivated scientists.  In our quest to live longer and better, a desire to fully understand the mechanisms that explain how and why we grow old, has been central to longevity research. In recent years some significant progress has been made. A clearer picture is emerging of the changes that occur, at a cellular level, that could dictate how our bodies respond to the passing years. In this episode of the LLAMA podcast, Prof. David Walker, a researcher at the University of California, Los Angeles, (UCLA) discusses his work with tiny worms and fruit flies, and explains the significance of myriad age-related issues, such as dysfunctional mitochondria, leaky intestines and inflammation.

Recorded: March 2, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Disclosure: Prof. Walker is a member of the scientific board of JUVICELL, a sponsor of this LLAMA podcast episode. 

Topics covered in this interview include:

• Dr. Walker's academic journey from Belfast to Manchester and Los Angeles. 
• Inspiration through  Jonathan Weiner's Time, Love Memory - a biography of Seymour Benzer, the biologist renowned for his study of genetics through experiments with fruit fly genes.  
• Working with nematode worms and fruit flies.  
• Aging - a great scientific mystery.  How our understanding of what is driving aging, at a cellular level, has evolved. 
• Developing novel ways, using genes, to prevent age- related health decline.  
• Changing awareness of aging as we grow older.
• Accumulation of dysfunctional mitochondria and how it appears to be an important cellular hallmark of aging. 
• The importance of autophagy for maintaining cellular health.
• Why do we age at different rates?  
• The pathophysiology of aging: How do age-related changes that affect organ function, relate to the health and viability of the aging organism?    
• Leaky intestines in fruit flies and humans . 
• Inflammation and the link to age-onset diseases
• Gut bacteria and relevance to various diseases and health interventions. 
• Diet and variability of our gut microbiome.
• High/low  protein diets and the aging gut, based on fruit fly studies.  
• Does eating less protein enhance longevity? 
• Making better informed decisions about diet and dietary supplementation. 
• Practicing "  common sense" lifestyle goals. 
• Exercise and everyday diet    to counter the effects of aging. 
• Memory loss  as we age and a better understanding of the mechanisms involved based on studies with fruit flies. 
• Lifestyles focussed on living life to the full.

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast sha

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Baby boomers make up a significant portion of the world's population.  In the US and the UK the generation born between 1946 and 1964 represents about a fifth of all people and is a hugely influential group.  So what's it like to be a boomer in 2021?  Many are still working, physically active and important contributors to the economy.  Others are retired and enjoying the fruits of their careers, while some are facing up to the challenges of life as a septuagenarian.  

"My almost fervent, religious conviction is we can all do better," says Dave Frost, a decorated naval officer,  world-ranked oarsman and Master Fitness Trainer.  

Dave was born in 1953. The San Diego-based author of KaBoomer: Thriving and Striving into Your Nineties is the founder of Well Past Forty, a company that promotes wellness and fitness for athletes of all ages and abilities. In this LLAMA podcast interview, with Peter Bowes, he discusses his gregarious approach to life, ambitious athletic goals and plan to "live large" into his tenth decade. 

Recorded: March 16, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• What is it like to be a baby boomer in 2021?
• Dave's definition of the "encore" years and what it means to live in the "best act yet" of our lives. 
• Living through the bottom of the happiness curve.
• Figuring out the daily activities, including motion and purpose, that enhance life. 
• The life-changing impact of 911. 
• Embracing the Loma Linda, low stress, outdoor lifestyle, for longevity. 
• The importance of breathing for everyday health and good sleep. 
• The joy of distance running and how the runner's high can be achieved with alternatives forms of exercise, as we get older. 
• The value of exercise, quiet time, mind-body alignment  and "living large" as we age into our nineties. 

"We know aging is unavoidable, but we don't have to get old."

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Why do we rush to the refrigerator during commercial breaks, while watching television?  Are we really hungry or does TV fuel our addiction to foods that we know are bad for us? 

"Without your agreement at all, you're doing what we call the robot walk or the zombie walk to the kitchen to get something to eat," says Joan Ifland, Ph.D., author of the textbook, Processed Food Addiction. 

Dr. Ifland believes we are wired to snack, in response to stress, excitement and suspense, and that an addiction to sugar and processed food is making us sick. In this LLAMA podcast interview, with Peter Bowes, she discusses her mission to help people recover from an addiction to processed foods and why, she says, cleaning up our diets, especially ridding them of sugar, could add years to our lives.

Recorded: February 18, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

In this interview we cover: 

• Melding the worlds of business and nutrition research
• Exploring what Dr. Ifland says is the role of corporations "in the spread and maintenance of addiction to processed foods"
• What is processed food? 
• The difference between processed plant and animal-based foods. 
• Food cravings, marketing, stress and addiction. 
• How do we take control of what we eat, to avoid unhealthy foods - or "bad" foods - and what Dr. Ifland describes as "artificial aging" 

"Somebody who is seventy years old can feel fifty or even forty or they might feel better than they've ever felt in their lives."

• Why is it so difficult to give up certain foods
• What is "conformance drive" and how does it influence what we eat. 
• Associating with others, online, to build an immersion experience with healthy people
• Dr. Ifland's diet change, 25-years ago, that she says eliminated cravings and "brain fog"
• Why do we fall off the wagon and return to bad eating habits? 
• How does the Addiction Reset Community work?
• The connection between watching the television and eating too much. 
• The impact of Covid on "clean" eating and food addictions. 
• The "purpose" of living a long healthy life

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

At the age of eighty-one, Jean Ketcham is looking forward to sky diving again, when the pandemic is over. The co-founder of Aging But Dangerous, an international women's movement promoting active, healthy aging, is on a mission to empower women over fifty to live their lives to the full.  When Jean retired, she and her friend, C. Suzanne Bates, realized that their social circles were shrinking and that their friends were becoming less adventurous. Convinced that life still had much to offer, the pair set up the group to encourage women to live dangerously, as they age. In this LLAMA podcast interview, with Peter Bowes, Minneapolis-based Jean discusses her zest for life, optimism and aspirations for the next two decades. 

Recorded: February 2, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Challenging the "trauma" experienced by women turning 50 
• What's wrong with the word 'aging?'
• Cataract surgery at 80 
• Setting up Aging But Dangerous
• Inspiration from Jane Fonda and Lily Tomlin
• Martini Jump Skydives, fashion shows and colonoscopy prep parties for women over 50  
• Inner strength, positivity and surviving cancer 
• Finding the silver lining in the face of negativity 
• Embracing social media, hosting Facebook lives for a multi generational audience
• Jean's advice to her younger self about weight and self-esteem 
• Having fun full-filling a mission to connect with and help women 
• An octogenarian's bucket list and aspirations 

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

If you're a fast walker, you're likely to live longer. The correlation between walking speed and lifespan has been widely studied and is a good indicator of our general physical condition and the number of years that we are able to enjoy optimum health. "It is a wonderful predictor," says, Dr. Cliff Bleustein, Global President and CEO of AposHealth, a home based exercise program aimed at helping patients with their mobility. In this episode we delve into the importance of a healthy gait, sometimes described as the sixth vital sign. Dr. Bleustein explains the link between the natural ability to take a brisk walk and maximally performing bodily systems, such as the heart, lungs and musculoskeletal. 

Recorded: January 26, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Dr. Cliff Bleustein's "eclectic" career, encompassing surgery, research, business and healthcare consulting. 
• Making the shift from treating patients to the business of healthcare 
• Treating osteoarthritis of the knee by changing the way people walk 
• Earlier health management of chronic conditions to improve health outcomes
• Rehabilitation based on physical therapy rather than surgery 
• Purposely including short bursts of exercise during the day for optimum health and maintenance of muscle mass
• The cumulative impact of exercise
• Gait - the sixth vital sign and predictor of long life. 
• Walking speed as an indicator of health
• The daily activities that cost nothing and promote physical health 
• The impact of Covid-19 on general healthcare, and the switch to telemedicine 
• Future problems caused by plummeting activity levels during the pandemic 
• The physical and emotional health impact of taking fewer steps a day through working at home
• Why healthcare facilities should be considered safe for preventative interventions, even as Covid continues to be a threat
• Taking small steps every day to pursue health and longevity. 
• There are only so many things we can control.  Don't worry! 

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Nutritional supplementation is one of the most frequently raised topics in relation to longevity and healthy living.  But do we really need additional components in our diet, such as pterostilbene , sulforaphane and resveratrol?  Scientifically validated studies suggest some dietary supplements are beneficial to our health, but how do we decide which ones to take?  There are myriad considerations. To explore the subject, the LLAMA podcast is teaming up with JUVICELL, a nutraceutical product developed by US and German scientists. In this conversation with Peter Bowes, co-founder, Erin Sharoni, discusses the scientific, ethical and societal issues involved in developing a product that aims to extend healthspan. 

Recorded: February 15, 2021 | Read a transcript and show notes at the LLAMA podcast website.

• The study of epigenetics and what it means. Our internal and external environments and how they interact.   
• Erin's "obsession" with the human body and how it changes over time.  
• Does living like an elite athlete help us live longer?
• The basic protocols for good health, like sleep, diet and hydration that impact longevity 
• The most basic lifestyle traits that help us thrive.
• Why there is no magic bullet to optimum health.  
• The insurance policy approach to dietary supplementation.      
• The power of fasting and the work of Dr. Valter Longo at the university of Southern California (USC).   
• The idea and mission behind JUVICELL
• Why the mission is to help people optimize healthspan rather than lifespan.
• Explaining the ingredients that go together to form an all-in-one dietary supplement. 
• Safety, supplementation and ethical responsibility to follow the science. 
• Lessons from the Covid pandemic and the big changes needed at a societal level to enable healthier populations. 
• Sleep, whole foods, meditation and other lifestyle components to promote every day health and longevity.  

This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.com

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Cognitive decline is an all-too-familiar hallmark of age-related diseases, such as Alzheimer's and Parkinson's. While there is much research that focuses exclusively on functional changes in the brain, the so-called gut-brain axis  - a connection between the digestive system and the central nervous system - also appears to play a pivotal role. It raises the question: Could nutritional interventions, to nurture the health of the gut microbiome, also help prevent or reverse age-related dementia?  In 2018, Dr. Julie Andersen, a scientist at the Buck Institute for Research On Aging, in California, received a $3.8 million grant to explore the hypothesis.  In this LLAMA podcast episode, Dr. Andersen discusses the work of her laboratory, and the idea that a gut metabolite, urolithin A, could play an important role in the treatment of Alzheimer's disease. 

Recorded: February 9, 2021 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Working at the Buck Institute for Research On Aging - the only freestanding institute studying aging and age-related disease.
• A multi-disciplinary approach to aging research, embracing a range of diseases and mechanisms that drive-age related conditions. 
• Evolving definitions of aging.
• Exploring autophagy, mitochondrial function, urolithin A and muscle health, in relation to Parkinson's and Alzheimer's disease. 
• The science and logic behind restoring an older person's gut microbiome to that of a younger person. 
• Building on "exciting" clinical trials, by Amazentis, looking at the efficacy, in older humans, of Urolithin A, to enhance muscle function.
• Exploring the relatively new area of study known as the gut-brain axis.
• Explaining the scientific process, grants and clinical trials.
• How preliminary preclinical trial data suggests urolithin fed to mice may prevent cognitive loss associated with Alzheimer's disease.  
• Turning 60 and aspirations for a long healthspan. 

This episode is brought to you in association with Amazentis, a Swiss life science company, that is pioneering cutting edge, clinically validated cellular nutrition, under its Timeline brand.

Related episodes:

• David Katz: Robust health beyond the pandemic
• Stuart Phillips: Boosting physical strength as we age
• Stephanie Blum: Embracing and marketing the science of wellbeing
• Johan Auwerx: Enjoying youthful vitality as we age
• Navindra Seeram: The rejuvenating power of plants
• Patrick Aebischer: A novel molecule to promote longevity
• Anurag Singh: Pomegranates, muscle mass and healthy aging

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult y

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

When the pandemic struck, instead of hunkering down, with her life on hold, Alison Weinlaeder moved into top gear with her brain-child, a new online business melding physical and mental workouts.  The speech-language pathologist, from Saint Paul, Minnesota, wanted to help people improve their cognitive abilities, at the same time as nurturing their cardiovascular fitness. Cardiomelon is a fitness program that puts the essential components of daily health at its core. In this LLAMA podcast interview with Peter Bowes, Alison explains the science behind her novel approach to fitness.  She also shares the challenges and rewards she enjoys through a startup focussed on helping people live longer and better.

Recorded: January 22, 2021 | Read a transcript and show notes at the LLAMA podcast website.

This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.com

Topics covered in this interview include:

• Why we should work on keeping the brain healthy and strong as well as the body
• Working, as a speech language pathologist, with people who've experienced tragic and traumatic events
• Pushing the brain outside its comfort zone
• The challenged posed by virtual therapy for patients with severe brain injuries
• Launching Cardiomelon in the midst of a pandemic
• Isn't it just normal to forget things as we get older? 
• Empowering people through brain-focussed exercise 
• How gardening  and walking can help boost brain performance.
• Building a brain workout programme based on the concepts of rehabilitation - the principles of neuroplasticity
• Why you've got to use it to improve it
• Why just doing mental workouts, without always succeeding in a challenge, will improve brain health  
• Never too late or early to start.  
• Partnering with Hilarity for Charity with a mission to educate people in their 20s about poor health habits that could lead to Alzheimer's 
• The evidence to support combining cognitive and physical exercise
• Learning how to think smarter, through visualization and habits 
• Being empowered to control brain health
• The lifestyle habits that will determine how our lives will be like, decades in the future.
• Future science-based  research into the outcomes from Cardiomelon

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

After a diagnosis of lupus, in her 30s, Leslie Kenny was told she had a life expectancy of five years. The prognosis focussed the Berkeley and Harvard grad's mind like never before. Long before biohacking was a thing, Leslie set about changing her lifestyle, embracing safe, natural solutions, in a fight for her life. Now 56, she is aging well, healthy and a fully signed up biohacker. She is the founder of Oxford Healthspan, a UK-based company, working with leading scientists to identify safe compounds as nutritional supplements. In this LLAMA podcast conversation with Peter Bowes, Leslie discusses her own unique journey, as well as the science and life-enhancing potential of spermidine, a compound that has been shown to be vital to myriad bodily functions. 

Recorded: January 19, 2021 | Read a transcript and show notes at the LLAMA podcast website.

This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.com

Topics covered in this interview include:

• Leslie's journey from Swiss banking to biohacking 
• Facing up to Lupus and a five-year life expectancy 
• One's own mortality and the limits of longevity
• Pillars of preventative healthcare: sleep, movement , diet, friendship, family
• Why your health is your wealth
• Discovering the polyamine compound spermidine and establishing Oxford Healthspan 
• Where does the name spermidine come from and what is it? 
• The evidence for the benefits of spermidine - epidemiological  studies and clinical trials 
• Is spermidine supplementation safe? 
• How do consumers make decisions about which supplements to take?  
• Living life with the promise of healthspan rather than lifespan 
• Disease prevention versus disease care 
• The lifestyle of a biohacker - sleep hygiene, good food, lowered stress

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

It is often said that it is never too late to adopt a healthy lifestyle - never too late to incorporate more exercise into our daily routine or focus on a healthier diet, to reap the rewards as we age. In reality, a message that it is never too early to focus on our wellbeing and longevity, is equally important. Perhaps more so. Cathy Richards is an exercise physiologist and founder of Inspiring Vitality, an online coaching program focussing on the needs of people over 40.  In this LLAMA podcast interview with Peter Bowes, Cathy discusses her mission to encourage more people to take steps - even tiny steps - in their daily lives, to incorporate strength building activity into their routines.  She also highlights the significance of deteriorating hearing for overall health and the likelihood that impaired hearing can lead to social isolation and loneliness.

Recorded: January 11, 2021 | Read a transcript and show notes at the LLAMA podcast website.

This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.com

Topics covered in this interview include:

• Adapting to a new way remote way of working out during and likely after Covid
• Learning about the behavioral trail of very old populations and joining the longevity dots
• The onset of frailty and the snowball effect of muscle decline
• Implementing resistance training into exercise regimes to maintain muscle strength
• Doing the bare minimum exercise to still realize significant result. 
• Small, step and changes that add up and make a difference over time
• Persuading younger generations that it is never too early to think about being fit at 85. 
• Hearing loss and the impact on our quality life as we age  
• The stigma associated with hearing loss and dangers 
• The correlations been hearing loss and dementia. 
• Social isolation, poor hearing and loneliness. 
• Personal habits to live a healthy day
• Sleep as a wellness trend

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

As we push the boundaries of human longevity and our expectations for lifespan, mid-life is going to be different.  Our healthy, vibrant decades are being extended. The goal of enjoying more fulfilling years, free of diseases and physical decline is becoming a reality. The trajectory of our lives is changing.  Chip Conley is a veteran executive in the hospitality industry, formerly Head of Global Hospitality and Strategy with Airbnb and a prolific writer.  He's also the founder of the Modern Elder Academy, a self-styled school for midlife wisdom and the author of Wisdom@Work: The Making of a Modern Elder. In this conversation with Peter Bowes, Chip shares his vision of older people as wise, curious and indispensable members of society. He recalls the impact of a near-death experience, the way his life went through a transformation in his 50s and the art of lifelong learning.     

Recorded: December 29, 2020 | Read a transcript and show notes at the LLAMA podcast website.

Photo credit: Lisa Keating

This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.com

Topics covered in this interview include:

• Chip's life-defining brush with death and experience of going to the "other side" during a medical  emergency. 
• Doing business as a "hospitality disrupter," as one of the first boutique hoteliers and later with Airbnb.
• Creating the Modern Elder Academy (MEA), mid-life wisdom school.
• What is long-life learning? 
• The unexpected pleasures of aging.
• Focussing on "great longevity" and a spiritual diet. 
• Upgrading the human operating system - moving from reverence to relevance as a "modern elder." 
• Launching the MEA - a regenerative community - a 21st century version of a retirement community. 
• Taking the less traveling path in life.  
• Having regrets or no regrets in life?  
• Metabolizing and cultivating wisdom from life's experiences.
• Acknowledging and challenging "new year resistances" fears and old habits.  
• Role models for a living a very long life.  
• Embracing curiosity as tool to live a long life. 

The Live Long and Master Aging (LLAMA) podcast is a HealthSpan Media LLC production. LLAMA shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The body's unique ability to repair itself, with a little outside help, is the focus of a growing sphere of longevity science. One area of research concerns a molecule, known as nicotinamide adenine dinucleotide (NAD+), which plays a key role in many biological processes.  NAD+ declines as we age, but research has shown that, through supplementation,  youthful levels can be restored, helping us to age better.   

In this episode, Dr Nichola Conlon, a molecular biologist and co-founder of Nuchido Laboratories, based in North -East England, discusses her mission to develop nutraceuticals to stimulate rejuvenation. 

In conversation with Peter Bowes, Nichola explains her passion for nutritional interventions designed to enhance healthspan; she addresses the need to educate people about the relevance of biogerontology research and the new products that could significantly improve our quality of life. 

Recorded: December 3rd, 2020 | Read a transcript and show notes at the LLAMA podcast website.

“This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.com

Topics covered in this interview include:

• A career in science driven by Nichola's fascination with the human body - how "it's so intricately designed and perfect to make us tick."
• How do drugs work - from consumption to the cells where they need to work. 
• What is aging? 
• The steep learning curve involved in aging research.
• Is it a good thing to try to slow aging and should it be done through supplementation?
• Translating the science into consumer products. 
• What does Nuchido mean? 
• Explain the role and complexities of NAD+
• The benefits of elevated NAD levels, related to aging. 
• Why reverse a process (declining NAD) when it appears to be a natural part of aging? 
• Why we are very good at being young but not so good at being old. 
• Being a successful female scientist and entrepreneur in a male-dominated world.
• The importance of tracking your own health through regular blood tests. 
• Why the sky's the limit in biogerentology.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Optimism, during this tumultuous year, has been in short supply. But as 2021 beckons, there is a real sense of hope that happier, healthier times are ahead. Cheryl Ladd, best known for her role in the 1970s detective series, Charlie's Angels, is also emerging from a rollercoaster of a year.  As well as dealing with the emotional challenges presented by Covid-19, for the first time in her life, the actress says she started to feel old.  But it was the challenge of failing eyesight that motivated her to take on a new mission in life, encouraging others, with optimism and gratitude, to embrace the aging process.  In this LLAMA podcast interview with Peter Bowes, the 69-year old explains why wellness matters; how she has overcome cataracts with new technology; her reluctance to retire and future aspirations in Hollywood.

Recorded: September 17th, 2020 | Read a transcript and show notes at the LLAMA podcast website.

“This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.com

Topics covered in this interview include

• The rocket ship that was Charlie's Angels and a 44-year career
• Mastering the process of growing old with optimism 
• Dark times through isolation during the pandemic 
• The healing power of a hug
• Appreciating what we have and expressing gratitude
• I'm 69-years old.  How did this happen?
• Changing sleep patterns as we age.
• Appreciating what we have and expressing gratitude
• Dealing with eye cataracts and a fear of driving at night 
• What is there to love about life and keep living for? 
• Retirement or not? 
• Being old and female in Hollywood.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

If the coronavirus pandemic has reminded us of anything, it is that there is nothing more important than our health and wellbeing.  Now that the vaccine is a reality for people in the UK - and the rest of the world soon -  there is real hope that the disease will be brought under control during the first part of next year.
 
"People in robust good health are massively less vulnerable to bad outcomes during the pandemic and more vital in general," says Dr. David Katz, a physician and co-author of the new book, How to Eat. Highlighting the importance of lifestyles and nutritional interventions, to promote health and vitality, Dr Katz says, there is much to be done tackling the "neglected scourges” of modern living, as we move on from the pandemic.

A renowned public health commentator and prolific writer, Dr Katz serves on the Scientific Advisory Board of Amazentis, a Swiss life science company and co-producer of this LLAMA podcast episode. In this interview, with Peter Bowes, he analyzes the current state of Covid-19; the challenge of sorting fact from fiction; the prospect of “herd immunity” and life after the virus. He also delves into the infinitely fascinating world of the microbiome and nutritional products that promote enhanced muscle mass and function as we age.

Recorded:  December 1st, 2020 | Read a transcript and show notes at the LLAMA podcast website.

This episode of the LLAMA podcast was brought to you in association with Amazentis, a Swiss life science company, which is pioneering cutting edge, clinically validated cellular nutrition, under its Timeline brand.

Topics covered in this interview include

• How a rambunctious kid chose a career in medicine and developed a passion for preventing chronic disease, and promoting health.
• Analyzing the lifestyle practices that determine our state of health.
• Drama over data and the Covid-19 pandemic. 
• What does herd immunity mean? 
• Pandemic fatigue, opening up society and phasing back to normalcy.
• The "acute case for chronic health" as we emerge from the pandemic. 
• Mitochondrial health,  the microbiome, pomegranates and urolithin A. 
• Amazentis' nutritional product Mitopure and clinical trials suggesting a positive impact on physical stamina and endurance. 
• Can rejuvenation of mitochondria mimic the health of the world's fittest communities?
• Sleep, diet and exercise. 

Related episodes

• Stuart Phillips: Boosting physical strength as we age
• Stephanie Blum: Embracing and marketing the science of wellbeing
• Johan Auwerx: Enjoying youthful vitality as we age
• Navindra Seeram: The rejuvenating power of plants
• Patrick Aebischer: A novel molecule to promote longevity
• Anurag Singh: Pomegranates, muscle mass

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The concept of healthspan - the number of years that we enjoy optimum health - has come a long way, in recent years.  In fact, Dr. Nir Barzilai, founding director of the Institute for Aging Research at Albert Einstein College of Medicine,  believes we are "ushering in a future where the norm will be for people to be healthy, active and mentally sharp, during the last quarter of their lives."  In his new book, Age Later: Healthspan, Life Span, and the New Science of Longevity, he argues that aging can be "targeted, improved and even cured," and that it should be thought of as not "as a certainty but as a phenomenon."  In this LLAMA podcast episode, with Peter Bowes, Dr Barzilai, discusses his life's work studying some of the world's super agers, people who are enjoying active and productive lives well into their nineties and beyond.

Recorded:  September 21st, 2020 | Read a transcript and show notes at the LLAMA podcast website.

Topics covered in this interview include:

• Dr Barzilai's lifelong interest in longevity and healthspan
• The impact of Covid 19 and why it has highlighted issues surrounding agism. 
• Post-covid and finding the right balance with social interactions. 
• The TAME (Targeting Aging with Metformin) study and wider uses for the anti-diabetic drug, relating to aging, coronavirus and cancer. 
• Should we all be taking metformin?  The ethical dilemmas. 
• Why "flexible" biology of aging. 
• What has been learned through the study of 750 centenarians?
• Learning lessons from Frieda - the grandmother of Dr. Barzilai's wife. 
• Why we should not put off our dreams. 
• The longevity dividend.
• Caloric restriction, fasting and time-restricted eating.
• Getting enough sleep.

Earlier LLAMA podcast in with Dr. Barzilai: Researching the genetics of exceptional longevity and drugs that could target aging

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Lee Gutkind has spent much of his life denying his age. The Pittsburgh-based writer and teacher, renowned for his skills as an immersion journalist, has long been fascinated by the aging process and the insecurities that come with growing old. Now, aged seventy-seven, he has overcome his anxieties and age-related tensions. It followed a dark period of time, marked by the loss of loved ones and loneliness, when Lee decided to use his journalistic skills to perform a deep dive on himself. The result is a candid memoir, My Last Eight Thousand Days: An American Male in His Seventies, which documents the realities of aging and the transformation in fortunes that Lee enjoys today. In this episode, he explains how, despite a hugely successful career and a naturally outgoing personality, he reached a low point in his life; how he developed a new appreciation of casual friendships and the joy of connecting with other people. Described by Vanity Fair as the Godfather behind creative nonfiction, Lee also reflects on the frustrations that come with being pigeonholed as an old, soon-to-be-retired, man. 

Published: November 12, 2020 | Recorded: November 10, 2020

Visit the LLAMA podcast website for complete show notes, including a transcript of the conversation.

This episode is brought to you by AgeUp, a new product that helps fill in the financial gaps that are often created once you’ve mastered aging and achieved an exceptionally long life. Small monthly payments to AgeUp stack over time to create a secure income stream for your 90s and beyond. Contributions to AgeUp are shielded from market swings, and once payouts begin at age 91 or above, they’re guaranteed to last for life. AgeUp is backed by MassMutual and sold by Haven Life Insurance Agency. You can find out more at Age-Up.com

In this interview we cover:

• The life and times of an immersion journalist, who immerses himself into his own story
• Dispelling the popular image of an older person
• Defending the vitality of people still working in their seventies 
• The “demeaning” assumption that retirement beckons at 65
• Lee’s denial of his age and mid-life loneliness 
• Turning the journalistic microscope inward with positive results
• The realization that casual friends can be a lifeline
• The power of human interaction after a lifetime of self-enforced solitude, as a writer
• The impact of Covid on friendships
• The physical prowess of a lifelong athlete in his 70s
• The excitement of hot yoga at 70 
• Moving forward while remaining younger in mind and body

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Matters of the mind may be more important to us now, than ever before. The number of new coronavirus cases is continuing to rise in many countries.  The United States - as well as dealing with political uncertainty - is reporting over 100,000 infections every day and England has just gone back into lockdown.  There are encouraging exceptions, like Australia, which, earlier this week, recorded its first day without local cases in almost five months. But our lives have been upended like never before, and as we continue to battle the virus, the pandemic brings into focus our overall health and wellbeing. 

“When there’s a huge event like Covid, it’s a forced pause for all of us,” says Giovanni Dienstmann, a Sydney-based meditation teacher and creator of the blog, Live and Dare.

Is it time to re-think the way we live our lives and contemplate the future?

"Perhaps start a different life, perhaps start to focus more on family, on personal growth, on health and longevity and on service."

In this episode, we explore the power of meditation to get us through these difficult days.  Giovanni also discusses his personal journey, from troubled child to a place of contentment - and his regimented lifestyle, encompassing meditation, work, exercise, one daily meal, stoicism and family.

Published: November 5, 2020 | Recorded: August 27, 2020

Visit the LLAMA podcast website for complete show notes, including a transcript of the conversation.

This episode is brought to you by AgeUp, a new product that helps fill in the financial gaps that are often created once you’ve mastered aging and achieved an exceptionally long life. Small monthly payments to AgeUp stack over time to create a secure income stream for your 90s and beyond. Contributions to AgeUp are shielded from market swings, and once payouts begin at age 91 or above, they’re guaranteed to last for life. AgeUp is backed by MassMutual and sold by Haven Life Insurance Agency. You can find out more at Age-Up.com

In this interview we cover:

• Nurturing the mind as well as the body
• Mastering the aspects of our lives that we can control
• The impact of Covid 19 on the demand for meditation
• Giovanni’s story: from troubled child to a place of restfulness. 
• Almost becoming a monk at 19
• Is spirituality religious?
• Classifying meditation into different disciplines: Concentration, awareness, relaxation and standby mode
• Developing the muscle of concentration
• Shutting out the modern day distractions in life and developing self-discipline
• Giovanni’s constantly evolving and adapting daily schedule
• Practicing biphasic sleep - splitting sleep into to blocks per day
• The importance of routines in daily life
• Eating just one meal a day. 
• Starting the day with a cold shower followed by meditation 
• Embracing intermittent fasting for longevity and wellbeing
• Living by a stoic philosophy and letting go of what you cannot control
• Putting life in perspective during the pandemic 

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise reg

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

They say, 'you’re never too old.' Never too old to do something for the first time, take on a new challenge, push yourself to your physical and mental limits, or step out of your comfort zone. You only live once. But how many of us would embrace such an  adventurous attitude, in our nineties.  in this episode we meet the writer, Heidi Herman, who was inspired by her mother, to “spread more living onto everyday life.” At the age of 93, Íeda Jónasdóttir Herman set out to find ninety-three things she had never done before, with the intention of trying them between her 93rd and 94th birthdays.  In her book, On with the Butter! Spread more living onto everyday life, Heidi tells the inspiring story of her mother’s adventure and the zest for life she shared with her family and friends.

Published: October 28, 2020 | Recorded: October 22, 2020

Visit the LLAMA podcast website for complete show notes, including a transcript of the conversation.

This episode is brought to you by AgeUp, a new product that helps fill in the financial gaps that are often created once you’ve mastered aging and achieved an exceptionally long life. Small monthly payments to AgeUp stack over time to create a secure income stream for your 90s and beyond. Contributions to AgeUp are shielded from market swings, and once payouts begin at age 91 or above, they’re guaranteed to last for life. AgeUp is backed by MassMutual and sold by Haven Life Insurance Agency. You can find out more at Age-Up.com

In this episode we learn about:

• Íeda Jónasdóttir Herman's extraordinary enthusiasm for living life to the full. 
• What it means to spread more living onto everyday life. 
• Adopting an adventurous mindset and how it affects our brain function and potential to live a longer life. 
• The simple lifestyle trail and instincts that promote healthy living.
• Daily exercise routines that don’t involve going to the gym, include doing sit ups and holding an exercise plank while still in bed.
• Observing the stretching routines of animals. 
• Building extra movement into the day.
• Taking the long route around the parking lot to pick up the groceries
• The power of communal laughter, even during the days of Covid
• How Heidi helped her mother try ninety-three news things between the ages of 93 and 94.
  
  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

What if we run out of money, as we get older? 

If we live a very long, healthy and active life, will we be able to afford the kind of lifestyle that we aspire to, as a nonagenarian or centenarian?  The so-called longevity risk poses a dilemma for many people. The goal is to enjoy a vibrant healthspan but it could prove to be expensive.  

In this episode of the Live Long and Master Aging podcast we discuss the financial side of living a very long life. We also meet LLAMA’s new sponsor, AgeUp, a novel financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. We explore the idea of longevity annuities - sometimes called deferred income annuities - as a way to set up a stream of income for life beyond 90. 

Blair Baldwin, founder and general manager of AgeUp, explains how the product came about, he shares the research behind the concept, and breaks down how it works.

"If you have fewer worries about money and finances, especially when you imagine the future state, that can only help lower your levels of anxiety and can only correlate to a more healthy lifestyle, essentially, and a better chance of living a very long life."

Published: October 21, 2020 | Recorded: October 15, 2020

Visit the LLAMA podcast website for complete show notes, including a transcript of the conversation.

This episode is brought to you by AgeUp, a new product that helps fill in the financial gaps that are often created once you’ve mastered aging and achieved an exceptionally long life. Small monthly payments to AgeUp stack over time to create a secure income stream for your 90s and beyond. Contributions to AgeUp are shielded from market swings, and once payouts begin at age 91 or above, they’re guaranteed to last for life. AgeUp is backed by MassMutual and sold by Haven Life Insurance Agency. You can find out more at Age-Up.com

In this episode we cover:

• The story behind AgeUp and how Blair developed an interest in human longevity. 
• The challenge: Creating financially accessible products that “do a little good for the world."
• Family conversations about money and old age. 
• Attitudes towards extreme longevity and how they affect our perspective on money. 
• Setting in place a financial plan to create an income over the age 90 
• Why have an income stream so late in life?
• Weighing the options and assessing the longevity risk. 
• Involving the family and building in a safety net. 
• Longevity and Covid 19 - and the importance of a long-term view

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

A key pillar of human longevity is our ability to remain physically strong and active as we age. Frailty is an all-too-familiar downside of growing old. But there is much we can do to slow down and even reverse the process that leads to the weakening of our limbs.  In this episode of the Live Long and Master Aging (LLAMA) podcast, we delve into the latest clinical discoveries that could help us stay strong and vital for much longer. 

Prof. Stuart Phillips, director of the Physical Activity Centre of Excellence (PACE) at the Department of Kinesiology at McMaster University, Hamilton, Ontario, explains how laboratory research into mitochondrial health is being applied to human physiology. Dr. Phillips is a member of the advisory board of Amazentis, the Swiss life science company, which has partnered with the LLAMA podcast to produce this episode. 

This episode of the LLAMA podcast is brought to you in association with Amazentis, a Swiss life science company, which is pioneering cutting edge, clinically validated cellular nutrition, under its Timeline brand.

Published: October 6, 2020 - 3:21PM PT
Recorded: July 7, 2020

Visit the LLAMA podcast website for complete show notes, including a transcript of the conversation.

In this interview we cover:

• PACE - a a community access exercise facility for special populations over the age of 55
• The impact a period of muscular disuse has on the body 
• Why Covid has had such a marked effect on older people through inactivity 
• The classic image of the older, retired person and why the notion of aging being associated with a decline in our physical functions is being challenged. 
• Pursuing a goal of aging as healthily as we can for as long as we can.
• Understanding the phenomenon of Sarcopenia
• The condition known as frailty. 
• Ten thousand steps per day - why that number? 
• Type II diabetes and psychical activity.
• Working with Amazentis to explore the benefits of Mitopure, a pure form urolithin A, in humans.
• Making the connection between research in laboratory animals and humans."
• Lifestyles that give meaning to life.
• The protein question - how much and what kind? 
• The declining immune system with aging. 
• Why is exercise king and nutrition queen? 
• Is there a recipe for good exercise? 
• Why do we run marathons?
• The power of walking 
• Spreading the message of healthy aging through social media

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The science and marketing sectors don’t often intersect. But when clinically validated advancements emerge from the laboratory, this unlikely alliance comes into play.  In this LLAMA podcast episode we explore how cutting edge research can be applied to our everyday health and longevity. 

Dr. Stephanie Blum, Head of Translational Science at Nestle Health Science, is responsible for transforming  scientific discoveries to innovative product. In partnership with the Swiss life science company, Amazentis, her work involves identifying how Amazentis’ mitochondrial research and clinical trial data can be leveraged for novel nutrition products with proven health benefits.

Dr. Blum received her PhD in pharmacology and immunology. She developed a passion for immunology after gaining a complex understanding of how a person’s immune system can critically affect their health.

In this interview with Peter Bowes, Dr. Blum discusses the intricacies involved with marketing a science-focused nutrition product. She also reflects on the ways people have changed their health habits in the face of a world-wide pandemic and the steps we could take to increase our immune health, as we age.

This episode is produced in association with the Swiss life science company, Amazentis, which is pioneering cutting edge, clinically validated cellular nutrition, under its Timeline brand.

Published: September 21, 2020 - 3.09PM PT
Recorded: August 12, 2020

Visit the LLAMA podcast website for complete show notes, including a transcript of the conversation.

In this interview, we cover:

• Striking a balance between exploring exciting research and actually producing a nutritional supplement that consumers will trust.
• How a healthy immune system could better-position you to fight off infections.
• With the COVID pandemic, how a well-functioning immune system is the foundation to defend against a viral or bacterial infection.”
• Dr. Blum’s conviction that we can proactively contribute to manage our health, and not to wait until medication of an illness is needed
• Which kind of health supplements consumers have intensively purchased during the COVID-19 outbreak and how the pandemic has changed their outlook on every-day health habits.
• Why obesity is a risk factor in COVID-19 infection.
• What simple thing you can do every day to better strengthen yourself against infections and other illnesses.
• Why your body accumulates "cellular waste" as you age, and what this means for your health.
• How offering people a choice in the physical form of a nutritional supplement can make all the difference when it comes to buying into the product and being able to stick with it.
• The quality that makes you an excellent leader, according to Dr. Blum.
• The advice Dr. Blum has for rising female leaders and the steps she takes in her personal life to ensure a healthy life style.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The science of aging is rapidly evolving. Many of us are more aware of our capacity to live a long healthy life, than ever before. But the quest to understand human longevity - and perhaps figure out how we can slow down the process - is still a huge work-in-progress. Why do we age? Is it due to wear and tear on our bodies, is it all predetermined by our genes - or is there an invisible killer all around us, such as toxins in the environment, that is slowly eating away at our lifespan? These and many other compelling questions about aging are explored in a fascinating new book: Borrowed Time: The Science of How and Why We Age, by Sue Armstrong.  In this episode of the Live long and Master Aging podcast, Sue, a writer and broadcaster, based in Edinburgh, joins Peter Bowes to explore the latest research and the lessons to be learned from our growing understanding of what it means to grow old. 

• Published: September 13, 2020 - 07:25 PT
• Recorded: August 20, 2020

Visit the LLAMA podcast website for complete show notes, including a transcript of the conversation.

In this interview we cover:

• Delving into the massive canvas that is the enormous issue of aging, and why it parallels climate change in its importance for the future of mankind. 
• Adding life to years rather than years to life, as the main goal. 
• Why the medical profession is behind the curve on the process of aging.
• Why the goal of living to over a thousand or even forever is overly “narcissistic."
• Our genetically predetermined fate, and why plays a relatively small role in our actual lifespan.
• The centenarians that just keep on going and then die quickly
• The goal of compressed morbidity
• Peter’s meeting Roy Walford, one of the early proponents of a calorie restricted (CR) lifestyle for longevity. 
• The mixed results from CR experiments involving monkeys. 
• How society and marketing is pushing us into unhealthy lifestyles. 
• The scourge of diseases of the mind and the latest theories on what causes dementia and Alzheimer’s disease.   
• Ayurveda medicine and a holistic, whole body, approach to treating disease.
• Could air pollution account for a significant proportion of Alzheimer’s cases? 
• What is inflamm-aging?  Low grade inflation that could be accelerating the aging process.  
• The lessons to be learned from longevity research. 
• The relaxing, stress-reducing impact of yoga. 
• The aging immune system, the dangers of sitting down for too long.
• The mindful practice of eating: Why mealtimes should be stress-free and peaceful. 

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Eventually, we will all face the challenges that come with old age. We will have less strength and energy than we once had. But what if it were possible to rekindle the drive and physical endurance of youth as we grow older? 

Prof. Johan Auwerx directs the Laboratory for Integrated and Systems Physiology at École Polytechnique Fédérale (EPFL) in Lausanne, Switzerland, where he studies the mechanisms that control how metabolisms are controlled and the factors that make them more or less effective. Focussing on longevity, his team is using multiple animal species to test a specific compound, Urolithin A, which could potentially restore much-needed muscle strength and energy to people as they age. 

Prof. Auwerx’s peer-reviewed research, including joint studies with the Swiss life science company, Amazentis, has been published in leading scientific journals. 

In this LLAMA podcast interview, with Peter Bowes, Prof. Auwerx, discusses the critical need for an affordable solution to ensuring a long and healthy life; how a highly pure form of Urolithin A, known as Mitopure, could be the key to improving our cellular health and strength as we age; and the simple steps we can take to mitigate health issues later in life.

This episode is produced in association with Amazentis, which is pioneering cutting edge, clinically validated cellular nutrition, under its Timeline brand.

Disclosure: Prof. Auwerx is a scientific adviser to Amazentis and several other companies which make products to boost mitochondrial function. Learn more about the science behind Mitopure, a highly pure form of Urolithin A, from Timeline.

Full show notes at the Live Long and Master Aging website.

In this interview we cover: 

• The downside of a more sedentary life, either enforced by COVID-19, or as a function of growing old.
• Why each person’s metabolism functions differently and what this means for our diet.
• Making the transition from treating patients to medical research.
• Tackling the big questions regarding metabolic diseases and complex interactions of the human body and the environment. 
• The role of the gut microbiome and genetic makeup in long-term health. 
• Why gaining weight has different implications for the young and old Why people Iiving in one region of the world will digest certain foods more efficiently than people living in a different area.
• Research with nematode worms (C. elegans) as a model for human aging and longevity.
• Testing worm observations in human cells, using phenotype data.   
• How studies on extracts from pomegranates led to a better understanding of Urolithin A.
• Understanding the difference between healthspan and lifespan. 
• Promoting the benefit of physical activity based on observations in worms. 
• It is ethical to work on lifespan? 
• The impact of urolithin supplementation on endurance, based on evidence in mice. 
• The daily rituals that promote healthspan. 
• How lifestyle habits, such as exercise, environment and stress levels, can affect how

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

"Let food be thy medicine and medicine be thy food." The quote, attributed to the Greek physician, Hippocrates, encapsulates the importance of nutrition and the extraordinary ability of certain foods to enhance our wellbeing. In this episode of the LLAMA podcast, we explore the rich array of benefits to be gained from plant foods and natural products and discover why foods rich in compounds known as phytochemicals are hugely beneficial in preventing some chronic conditions. Dr. Navindra Seeram is a professor at the University of Rhode Island, College of Pharmacy.  A leading researcher in the science of plant foods,  Dr. Seeram explains how, growing up in South America, with a tradition of using food as medicine, he first became aware of the potent power of plants.  We delve into the unique components of pomegranate and other fruits, which can be used by the body to boost mitochondrial health.  

This LLAMA podcast episode is produced in association with Amazentis, an innovative life science company dedicated to employing breakthrough research and clinical science to bring advanced therapeutic nutrition products to life, under its Timeline brand.

Disclosures: 

• Dr. Seeram serves on the scientific advisory board of Amazentis, independently from his position with the University of Rhode Island.  

In this interview we cover:

• Growing up in British Guiana, a poor Third World country, learning about the power of plants as medicines. 
• Developing a career as a natural product chemist.
• Understanding the anthocyanins or the pigments which make cherries red, blueberries blue, strawberries red and pomegranates red.
• Defining phytonutrients and phytochemicals.
• Deriving drugs from natural sources like plants.
• Revealing the multi-layered qualities of the pomegranate.
• Trillions of gut bacteria and why they are vital to the way we function.
• The importance of urolithin A as one of the metabolites we get from pomegranates.
• Understanding why we respond in different ways to the potentially beneficial compounds found in fruits. 
• Being a responder or a non-responder to Urolithin A.
• Linking urolithin A to mitochondria - the powerhouse of the cell.  
• Mitopure™ -  a highly pure form of Urolithin A - and why it has the potential to “cut to the chase,” even for non-responders.
• Personalized nutrition and precision medicine. 
• Simple diets, spices, coffee and red wine. 
• Healthspan science, long-term wellbeing and reasons to keep on living. 

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The art and science of aging well is a complex business - a nuanced melding of a finely tuned diet, essential exercise and a healthy mind. For over twenty years, Prof. Luigi Fontana has been studying the lifestyle regimes that could help us live a longer, healthier life. One of the world’s leading experts in the field of human longevity, Dr. Fontana, a physician and professor of medicine and nutrition at the University of Sydney, takes a pragmatic approach to the aging process, railing against aspirations to live an excessively long life. The author of ground-breaking research on fasting and nutrition, he explores the wider issues involved in the aging process in a new book, The Path to Longevity: The Secrets to Living a Long, Happy, Healthy Life. In this LLAMA podcast interview, with Peter Bowes, Prof. Fontana argues that medical systems based on treating sick people should be replaced by a more holistic approach to the human body. He also philosophizes about life's "beautiful journey.” 

In this podcast we cover:

• Working as a longevity scientists in Australia, a country with free healthcare.
• The difference between healthcare and sick care. 
• Like unserviced cars, how unhealthy humans are accidents waiting to happen."
• The scourge of obesity, especially in children and the relationship with chronic disease.  
• Why living longer by itself is of "no importance"  
• Finding happiness and harmony in life.
• The environmental impact of high protein and keto diets.
• Living long thanks to the longevity gene? 
• The craziness of magical recipes to live longer. 
• The metabolic and molecular pathways that regulate the accumulation of damage.  
• Calorie restriction (CR) - the most powerful intervention to slow aging.
• Getting a phone call from CR pioneer Roy Walford. 
• The confusion of ‘intermittent fasting’ describing multiple, disparate regimes.  
• The limits of using mice and other animals as models for humans in longevity research. 
• The role of IGF-1 - Insulin-like growth factor 1.
• The 5:2 diet and what we eat on those non-fasting days. 
• Developing biomarkers that measure our response to interventions focussed on improving health.
• The importance of waist circumference.  
• The ‘religious’ extremes of longevity - vegetarians, vegans, carnivores.  
• Approaching aging like a master conductor or a fine artist. 
• A lack of exercise being the main public health problem of the 21st century. 
• Why sportsmen and women do not live particularly long lives. 
• The role of the matters of mind in longevity and pink noise. 
• The value of sleep in healthy aging and memory consolidation. 
• Stress, addictions and dopamine. 
• A philosophical view of iife and longevity.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

This episode of the Live Long and Master Aging podcast is the first in a series produced in association with the Swiss life science company, Amazentis.  It will explore the history of the company and the science behind its goal of promoting healthy aging. Professor Patrick Aebischer, chairman and co-founder of Amazentis, is a medical doctor, neuroscientist and longtime researcher.  He has held distinguished positions in his home country of Switzerland, as President of the École Polytechnique Fédérale de Lausanne (EPFL) and in the United States at Brown University in Providence.  In this interview we explore how an idea based on little more than “intuition” led to a deeper understanding of muscular strength, as we age, and the role of fruits such as pomegranates. We focus on urolithin A, a bioactive dietary metabolite that is naturally produced when eating certain foods, and how Mitopure, a highly pure, synthetic form of the compound, could help people avoid frailty as they grow older.

▸ This episode is produced in association with the Swiss life science company, Amazentis, which is pioneering cutting edge, clinically validated cellular nutrition, under its Timeline brand.

▸ Published: Jul 8, 2020

▸ Read a transcript and additional show notes at the Live Long and Master Aging (LLAMA) podcast website

▸ Also listen and subscribe at Apple Podcasts and You Tube.

▸ Listen to related episodes exploring the science behind Urolithin A and Mitopure

DISCOUNTS

▸ Time-line is offering LLAMA podcast listeners a 5% discount on its Mitopure products - Mitopure Powder, Softgels and Mitopure + Protein. Use the code LLAMA at checkout.

▸ DoNotAge.org is offering LLAMA podcast listeners a 10% discount on its range of products – NAD boosters, Sirtuin activators, senolytics and more. Use the code LLAMA during checkout at DoNotAge.org  Any health queries can be answered by emailing the team at hello@donotage.org.

The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

Support the show

We are bombarded with advice and information about diet and exercise, but what about the impact of friendship, optimism and kindness on our longterm wellbeing? It is eye-opening to discover that a strong support network of family and friends lowers mortality risk by about 45 percent, while volunteering your free time reduces the chances of early death by a staggering 20-60 percent, depending on the study. Science journalist Marta Zaraska is the author of Growing Young: How Friendship, Optimism and Kindness Can Help You Live to 100. In this episode of the LLAMA podcast, she discusses the peer-reviewed studies that suggest living to a great age is about more than what we eat or how much we move.  We cover how caring for children motivates us to keep on living and why Marta's long-held beliefs about aging and longevity were shattered through an understanding of the research.

Check out our website at LLAMApodcast.com and social media sites @LLAMApodcast

In this episode we cover: 

• Coping with Covid-19 in France, where the outlook is looking better, with no second wave of the virus yet.
• Becoming a mother and thinking more about health and longevity. 
• Why fixating on nutrition and exercise does not tell the whole story. 
• Delving into the science behind friendship, optimism and kindness. 
• What “Growing Young” means.
• The folly of “anti-aging."
• Why hugging and cuddling is good, most of the time.
• The extremes some people go to for human contact.
• The blood science that validates acts of kindness as a positive behavioral trail. 
• Oxytocin, serotonin and endorphins. 
• The science behind that fuzzy warm feeling. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

How many times have you heard about an older person doing extraordinary things, despite their great age? In recent weeks the story of the 100-year-old war veteran, Captain Tom Moore, has captivated millions, for his marathon fund raising efforts in the UK. Walking lengths in his garden he has raised more than £30m for the National Health Service, during the Covid-19 crisis. He is amazing. In this episode of the Live Long and Master Aging podcast we explore the lives of amazing people through the eyes of Dr. Noelle Nelson, a California-based psychologist, author of Happy, Healthy...Dead and collector of eye-opening stories through her Facebook page, Meet the Amazings. What are the common traits of older people who live their lives to the full, almost to the end? 

In this interview we cover:

• Aspiring to be to be happy, healthy, dead. 
• The lives of the very old - ordinary people doing extraordinary things.
• Compressed morbidity - reducing the time it takes for the final exit. 
• Why most of Dr. Nelson's longevity achievers are not famous.
• Joining the dots and connecting the common traits of people who reach a great age. 
• Positivity or optimism: Why it is a major predictor of happy healthy longevity.
• A passion: From growing tomatoes to looking at the stars
• A purpose: Sharing knowledge or the joy of competing - in ballroom dancing. 
• Physicality: Walking, climbing, dancing - how exercise has been shown to improve mind and body functioning. 
• The power of always looking forward. 
• The value of friends - or “anchors" - to get through life’s tough times. 
• Dealign with losing everything in one of California’s wildfires. 
• The value of please and thank you and self appreciation. 
• Exploring science-based lifestyle interventions to live better.

Editor’s note: This episode of the LLAMA podcast was recorded in Camarillo, California, on February 27th, 2020, three weeks before the state became the first in the U.S. to issue a stay at home order due to the coronavirus.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

We are in the war against Covid-19 for the long term. The virus is likely to be with us for many months, if not years, and as we emerge from the global lockdowns, everyday life is looking very different. Re-imagining a post-coronavirus world will likely involve changes that go to the heart of how we live - our diet, personal hygiene, social behavior and work/life balance.  As we learn more about the virus, it is becoming clear that a healthy body is a vital prerequisite to fighting the disease.  In this episode of the Live Long and Master Aging podcast, Dr. Aseem Malhotra, a London-based cardiologist, explains why he believes obesity is a prime risk factor for mortality from Covid-19.  He also suggests that the pandemic should act as a wake-up call for global populations, pursuing unhealthy lifestyles, consuming too much sugar and processed foods.

Dr Aseem Malhotra is a National Health Service (NHS) Consultant Cardiologist in the UK, and visiting Professor of Evidence Based Medicine, Bahiana School of Medicine and Public Health, Salvador, Brazil. 

In the episode we cover: 

• How a "horrendous state” of baseline general health, in many western populations, is relevant to Covid-19
• Ref. European Scientist: Covid 19 and the elephant in the room (April 16, 2020)
• The myths surrounding the health of people in Mediterranean countries. 
• What is optimal metabolic health? Blood pressure, waist circumference, blood triglyceride, HDL, and HbA1c levels.
• Nature:  Endocrine and metabolic link to coronavirus infection (April 2nd, 2020)
• Lifestyle lessons from Covid-19.
• Personal hygiene and why it matters. 
• Imagining the post-coronavirus world.  

Listen to Dr. Malhotra’s previous LLAMA podcast interview
Episode 03: Waging war against sugar

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There are some encouraging signs around the world that the Covid-19 curve is flattening in some places, while falling in others. During the course of this pandemic we are focussing, on this podcast, less on longevity and more on our immediate futures. But as life slowly evolves towards a new normal, there are many lessons to be learned from the pandemic and the role science plays in our lives. In this episode we catch up with Prof. Valter Longo, director of the Longevity Institute at the University of Southern California and director of the Longevity and Cancer Program at IFOM Institute of Molecular Oncology in Milan in Italy. The Italian scientist splits his time between his home country and the United States, both badly affected by coronavirus.  In this episode we discuss the role of scientists working alongside doctors, sharing advice on how to behave during the outbreak. We also discuss the implications for people following a fasting mimicking diet, during a time when the risk of infection by the virus is high. 

Earlier LLAMA podcast conversations with Prof. Longo:

1. March 7, 2017: Creating the fasting mimicking diet
2. January 16, 2018: Living to 110 on a science-based diet

In this interview we discuss:

• Personal insights into the progression of coronavirus in Italy and the United States.
• The debate over the use of chloroquine to treat patients with Covid-19.
• Was time wasted in the US through the lack of advice to wear masks in the early stages of the outbreak?
• Speculation on why California has significantly few cases than other large population centers in the US. 
• The work of Dr. Longo's Create Cures Foundation, including education and work to combat childhood obesity. 
• Geographic differences in the spread of coronavirus
• Helping front-line health workers treating patients with coronavirus.  
• The power of scientists and doctors working together as a team.
• Is it safe to go on a diet, or fast, during the coronavirus outbreak?
• Latest news on the Fasting Mimicking Diet and new clinical trials.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The coronavirus pandemic is threatening every facet of normal life. This episode of the LLAMA podcast was recorded before the global health crisis hit home for so many of us. It focusses on the work-life initiatives of a rapidly growing US company that could be a blueprint for how we live in the future.  But not until life returns to normal. VideoAmp founder and CEO, Ross McCray, is currently dealing with the huge challenge of running a software and data company, employing more than 230 people, from home. He is particularly focussed on providing employees with support for their general wellbeing, to match the facilities that they usually enjoy at the office. Ross is on a long-term mission to change the work-life paradigm. He wants to build a workplace model that nurtures the physical and mental fitness of employees, in an environment that prioritizes happiness and health span. This episode includes Ross’s original interview, with LLAMA’s Peter Bowes, and an update on the impact of coronavirus. 

In this interview we cover: 

• Is there a blueprint or formula for best workplace practices that you can incorporate to other companies to make people truly happier and more effective?
• Being highly energized throughout the day.
• Providing workplace 24/7 gym facilities, personal training, healthy food, mental health support. 
• Effectiveness and longevity during the working day. 
• Work-life harmony - a nuanced approach to a fluid lifestyle.
• Different lives, priorities and perspectives on life.
• Balancing schedules - from medical appointments to office meetings and being a parent.
• Clear, measurable goals and flexible work-time.
• Physical challenges, weight loss and muscle building, at work.
• A data driven approach to a new workplace model focussed on wellbeing.  

Coronavirus update:

• Dealing with the everyday changes due to the coronavirus crisis. 
• Adapting to a home-working environment with improvised gym equipment. 
• Streamed workouts for virtual meetups to boost morale and maintain fitness.
• Dealing with the uncertainly and unease. 
• Rising to the occasion with inspirational quotes and “uplift vibes” through company playlists.

 

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Coronavirus is the only topic on our minds at the moment. People are panic shopping, a national emergency has been declared in the United States and widespread travel bans have been implemented around the world. There is also much confusion over testing for Covid-19 and how we should be looking after ourselves as the pandemic unfolds. Living long and well may be our goal in normal times, but getting through the next few months is a greater concern right now. In this episode of the Live Long and Master Aging podcast, with Peter Bowes, Dr. Felice Gersh, a physician and integrative medicine specialist, discusses the practical implications of a disease that has gripped the world with fear and uncertainty. 

In this episode we cover:

• Coronavirus: the global threat and our response to it. 
• The impact on doctors’ surgeries and the rise of telemedicine.
• Social distancing - what it means and how to achieve it.
• The implications of a viral pandemic for dietary regimes - whether they be for weight-loss or longevity.
• Fasting, the immune system and eating to stay healthy.
• Surviving at home or in isolation.
• Are men and women equally vulnerable to coronavirus?
• Going into emergency mode and maintaing best health practices.
• Exercise regimes during a health crisis. 
• Calming the mind and dealing with the stress.
• Seeing beyond the crisis and helping each other.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your own doctor or professional health adviser. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The ticking clock is often used as a metaphor for life. But is a tick-tock approach to the advancing years an accurate way to measure the aging process? Dr. Joseph Antoun, a physician and CEO of the nutrition technology company, L-Nutra, believes a “biological aging score” is the best way accurately to assess our state of health. He says the human body has the potential to age more slowly than its chronological age, and health care should be based on a better understanding of how well our bodies are performing, from the inside. L-Nutra, based in Los Angeles, is a company founded by the longevity scientist, Dr. Valter Longo, to develop and market a fasting mimicking diet. In this LLAMA podcast interview, with Peter Bowes, Dr. Antoun explains the philosophy and science behind a dietary intervention that is designed to promote longevity.

Check out our website at LLAMApodcast.com

In this interview we cover:

• Why aging is the biggest risk factor for the deadliest diseases of old age.
• Changing the medical paradigm to move away from pills and treatments post-disease onset.
• Engaging with new technology and science to keep people healthy.
• Investing more in disease prevention. 
• Partnering with Dr. Valter Longo, director of the USC Longevity Institute, to develop the fasting mimicking diet (FMD).
• Living healthier, longer and perhaps changing the world through dietary changes. 
• What does L-Nutra stand for? 
• The value of the prolonged fast and what happens to the body over 5 days of dietary restriction. 
• The difference between a fasting mimicking diet and a total water fast. 
• Weight loss, the short-term ticket, and the 5-day plan.
• Why the FMD is focussed on the long-term ticket - longevity and health span.
• Why the word ‘diet' may be misleading.
• Learning from the mass production and use of a product based on fasting.  
• The emotional impact of the FMD.
• Measuring the impact of a dietary intervention on a person’s potential to age better. 
• The value of a biological aging score as a unit of measurement for healthcare.
• Why Americans are living shorter lives, contrary to the popular belief that people are surviving for longer.

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Do we all fret too much about growing old and potentially suffering ill health? The purpose of this podcast is to highlight lifestyle interventions that could help us live longer, healthier lives. It focusses on extending health span - the number of years that we enjoy optimum health. But could it be that such aspirations are over-rated and rather pander to paranoid personalities. Dr. Magomed Khaidakov is a research assistant professor at the University of Arkansas for Medical Sciences and the author of A Pessimistic Guide to Anti-aging Research: Death is Immortal. The book offers a critical guide to current longevity research and anti-aging interventions. In this LLAMA podcast interview with Peter Bowes, Dr Khaidakov explains his skepticism towards aging research and why he believes longevity science is dogged by “hype" and "self-promotion."

Check out our website at LLAMApodcast.com
 
In this interview we cover: 

• Dr. Khaidakov’s conditions for growing old.
• Holding a pessimistic or realistic view of aging?
• The “hype" and "self-promotion” surrounding aging research.
• Are study results distorted through the use of obese lab animals?
• The "sweet spot" for good health based on Body Mass Index (BMI)
• Is an extra 10 years, which is "within design limits" of the human body, worth it?
• Life span in years for humans, rats, mice, flies and worms (yes we know C. elegans only live days) versus health span.
• Why every day aging and general health issues are problems that are "almost solved."
• The longevity business “driven by greed."
• Exploring the design flaws of the human body.    
• Health aging without effort “exploited” by those who devise health regimens.     
• Lacking self-discipline and smoking. 
• “Slightly paranoid personalities” who spend too much time pondering over their longevity. 
• The practical and philosophical issues raised by death. 
• Being content with a pleasurable life. No complaints. 
• Why biology will play second fiddle to big data science in the future. 

"It’s your personal decision whether you have a healthy lifestyle.”

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There’s an old saying that money doesn’t buy happiness. But what about lifestyle hacks to optimize wellbeing and overall health? David Hauser is a hugely successful businessman who has overcome multiple health problems and self-esteem issues - including weight gain, exhaustion and failed diets - to transform his life.  Once a slave to pseudoscience and fad diets, David says he eventually embraced real science and applied a data-driven approach to building an “unstoppable” lifestyle.  He is best known for co-founding the Grasshopper Group, a virtual telephone service, but the Las Vegas based entrepreneur has now taken on the role of self-help guru, empowering others in their quest for better physical and mental health.  In this LLAMA podcast interview, with Peter Bowes, David explains his “optimization mindset” and new-found zest for life.

Check out our website at LLAMApodcast.com

In this interview we cover:

• David’s journey from overweight teen to wellbeing evangelist
• Tackling brain fog and physical malaise
• Epidemiological studies - the pros and cons
• Arguments over misleading health headlines
• Plants based diets - reality, facts and myths
• Deep diving into data to set out a framework for wellbeing
• Sleep, meditation, mindfulness
• The meaning of deep breathing
• Daily routines without tracking
• Yoga - really! 
• Optimizing sleep environments and patterns
• Living with technology and keeping it at arm’s length
• Computers, TVs and phones
• Longevity goals and optimizing health span. 
• Experiences over things
• Building a legacy that matters

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Prostate cancer is one of the most commonly occurring diseases in men. There is a high survival rate and living a long life with the condition is possible for many men. There are also lifestyle changes that could delay the onset of the disease and help men achieve a long health span - the number of years they enjoy optimum health.  Dr. Mark Scholz is a prostate cancer specialist and a strong advocate for patient empowerment. In this LLAMA podcast interview Dr. Scholz explains why a prostate cancer diagnosis is far being a death sentence and how rapidly changing medical technology is changing the way doctors treat the disease.

Check out our website at LLAMApodcast.com

In this interview we cover: 

• The basics: What function does the prostate perform? 
• Why prostate cancer is considered a “low grade” cancer. 
• Aging and prostate health.  
• The choices available to men with prostate-related problems. 
• Prostate cancer - how serious is it and what are the implications for medium and longterm health?  
• Why the prostate cancer industry is a multibillion dollar affair.  
• Urinary health and longevity.  
• PSA - what it means and why PSA testing requires "a lot of sophistication" to extract full value out of the result. 
• Supplements, diet and lifestyle.  
• Health span versus life span. 

The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind you should consult your doctor.  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Frailty and a decline in overall physical strength are irksome signs of aging.  Regular exercise is essential to maintain optimum muscle mass and movement, but are there other interventions that could curb age-related muscle weakening?  A Swiss biotech startupis developing a supplement that could slow down the process, by replacing damaged mitochondria, the parts of cells that generate energy. It turns out that a key component could be a chemical produced by the gut microbiome, when we eat pomegranates and strawberries.  In this LLAMA podcast with Peter Bowes, Dr. Anurag Singh, Chief Medical Officer with Amazentis, explains the background to this developing science and its potential to help older people maintain an independent lifestyle for longer.

Check out our website at LLAMApodcast.com

In this interview we cover:  

• Research at Amazentis and company mission
• Dr. Singh’s transition from medical practice to medical research
• The role of mitochondria - the cellular powerhouses - and link to muscle dysfunction or decline
• Analysing the mitochondrial health of frail vs older, active adults.
• The connection between pomegranates, strawberries and nuts - and mitochondrial health. 
• The role of urolithin A and why it could be a valuable dietary supplement.
• Why microbiome health is linked to muscle strength.
• Why optimal diet is not equal to optimal health.
• The role of mitophagy. 
• Animal studies suggesting urolithin A supplementation promotes enhanced endurance and better mitochondrial function.
• What the first clinical studies with older, minimally active human subjects show. 
• The current fascination with longevity research and desire to function better for longer. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There are some people who just ooze optimism.  Approaching life with a positive and inquisitive attitude is half the battle, when it comes to aging with vigor and purpose. It also helps to be a little defiant and rebellious - if not, downright disobedient. Writer, businesswoman and model, Dian Griesel, has embraced the power of living agelessly through her blog, Silver Disobedience.  The author of The Silver Disobedience Playbook: 365 Inspirations for Living and Loving Agelessly, she delivers a daily dose of wisdom and pithy observations about life and aging.  In this LLAMA podcast interview with Peter Bowes, Dian shares the inspiration behind her gregarious attitude towards aging.  She also invites us to the party of a lifetime.

Check out our website at LLAMApodcast.com

In this interview we cover: 

• Does disobedience come with age? 
• Being enthusiastic rather than disillusioned with age.  
• Seeking inspiration from Mick Jagger.   
• Being honest about aging.
• Social media and living life as if it were a reality show.   
• The value of taking a deep breath and putting yourself first. 
• Why young people are “terrified” of aging.
• Embracing the treadmill desk.
• Keeping it close to earth: Avocados, nuts, fruits and vegetables. 
• The power of collective consciousness.
• Listening to the conversations of others for inspiration.  
• The power of community and rockin’ out together at 100.
• Committing to do something every day, like a blog. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Joel Einhorn lives life at a pace that sometimes defies gravity. The extreme sports enthusiast is an avid athlete - a cyclist, snowboarder and surfer.  His enthusiasm for the fast life almost ended in tragedy while training for an ironman triathlon, but the accident, in Prague, ended up opening Joel’s eyes to a new world of medicine. The founder and CEO of HANAH, a supplement company that embraces ancient wisdom and modern day science, is on a mission to preserve - and make more accessible - healing techniques from eastern medicine. In this LLAMA podcast interview with Peter Bowes, Joel reveals the aha moments that inspired his journey from severely injured cyclist to wellness entrepreneur. 

Check out our website at LLAMApodcast.com

In this interview we cover:

• Joel’s childhood and influences. 
• Being the kid always looking out of the window.
• Sports, acting and the quintessential American life. 
• Being an early adopter of computer tech.
• Going from casual athlete to ironman addict.
• Organising life and systems with military precision to optimise time for living life to the full.
• The accident in 2008 that turned out to be a major turning point in Joel’s life. 
• Racing through life, taking a few risks and then… a near-death accident that led to a life-changing attitude towards living. 
• Joel’s introduction to eastern medicine and the   healing power of herbal medicines. 
• The healing ‘secrets' of elite athletes.   
• Fasting - the fountain of youth?
• What is Ayurvedic medicine and what happens during panchakarma treatments?  
• Creating and building HANAH for high functioning humans.    
• Tackling the decision fatigue that comes with trying to live a healthier life

Warning: Fasting can be extremely dangerous and result in death. It is not appropriate for everyone. Speak to your doctor before adopting a new diet or fasting regime.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Fred Bartlit is on a mission to re-define aging. A distinguished U.S. Army commander and high profile trial lawyer - he represented two American presidents - Fred is now 87 and a passionate advocate for strength training as we grow old. The author of Choosing the Strong Path: Reversing the Downward Spiral of Aging, is, by his own admission, obsessed with pursuing a healthy lifestyle. Fred’s mantra is that if we “get strong” everything else will fall into place.  In this LLAMA podcast interview he explains his philosophy that strength drives everything - in life and business - and why men, especially “big shots” from the world of business, are less inclined than women to follow his advice.

Check out our home page at LLAMApodcast.com | Twitter: @llamapodcast

In this interview we cover:     

• Fred’s aspirations to remain strong and active into his 90s. 
• How medical science, he believes, fails to focus on optimum health over 75. 
• Life expectancy versus health expectancy.
• Fred was selected by two U.S. Presidents of different parties to represent them in high profile cases. 
• He represented President George W. Bush in the 2001 U.S. Presidential election 'hanging chad' trial.
• Fred was selected to be the president’s chief counsel for Barack Obama’s National Commission on the BP Deepwater Horizon Gulf of Mexico Oil Spill.
• How Fred’s future wife warned him that his exercise regime, at 50, would leave him a corpse at 60. 
• How lifting heavy weights transformed Fred’s body. 
• Why he was inspired to pursue research into sarcopenia, chronic diseases, fatigue, falls, and early death.
• Why he came to the conclusion that there is direct correlation between strength and happiness. 
• How Fred escaped being a “fat old fool” at the country club.
• Fred’s diet of brightly coloured vegetables and fruit. 
• What does "a pot belly can not lead men” mean? 
• Getting up at 3.30 AM and working out every day. 
• Still working as an active trial lawyer at 87 
• Why men won’t acknowledge their age-related frailties. 
• How you can avoid the downward spiral of aging.   

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

This is our 100th episode and we’re delighted to celebrate the milestone with a remarkable man. Zab Mosenifar, MD, recently completed his 100th marathon at the age of 70 and he personifies the art of living a long, healthy and fulfilling life. Dr. Mosenifar, professor and executive vice chair of the Department of Medicine at Cedars-Sinai Medical Center in Los Angeles, is addicted to running. Next week he heads to California’s Death Valley, to run in grueling heat that would see most of us wilt in a second.  It is the kind of “insane” challenge that motivates the doctor, who still works full-time and says he relishes living a modest life, focussed on his job and running.  In this interview we discuss Dr. Mosenifar’s 50 miles-per-week regimen, his love of red wine, orchids and a busy life.  We also find out why he is a stickler for punctuality; prefers driving in the middle lane; and why he gets a “special pleasure from monotony.”

In this interview we cover:

• Dr. Mosenifar’s 50 miles-per-week running regime.
• Running the Santa Monica mountain trails early in the morning, seven days a week.
• The runner’s high. 
• Entering a zen-like state and enjoying the euphoria of running. 
• Living a meat-free lifestyle. 
• Getting a “special pleasure from monotony” and enjoying a frugal lifestyle. 
• Are we really designed to run long distances? 
• The “hidden factor” that allows some people to keep on running. 
• Sharing a bottle of wonderful red wine.
• Eating the same meals every day. 
• Why associating with all generations helps promote longevity. 
• Appreciating that life is precious and why there should be no bad days. 
• Balancing a busy work schedule with an active life and family activities.  
• Career longevity at Cedars-Sinai Medical Center, Los Angeles.
• The “heart-wrenching” period treating patients with AIDS during the early days of the disease.
• Studying the complexities of smoking.
• Understanding aging through marathon running.
• The plus side of an obsessive, compulsive personality.
• Thinking about longevity, how to approach the next chapter and acknowledging the realistic decline that comes with aging. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

We will all get old, if we are lucky. Aging is a privilege, but facing up to the inevitable lifestyle changes, could leave some of us in denial. Steven Petrow is an award-winning journalist and author, best known for his candid essays in the Washington Post and New York Times, focussing on what it’s like to grow old. In this LLAMA podcast interview, recorded at TEDMED, Steven reflects on the aging process through the eyes of his parents and his own aspirations. He also discusses the challenges posed by loneliness, declining mobility and old age for LGBTQ people.

Check out our home page at LLAMApodcast.com
Twitter: @llamapodcast

In this interview we cover:

• Lessons and stories from the way parents live and age.
• Family tensions and a father’s frustration at growing old. 
• Defiance over getting old.
• Like father, like son - shared traits as we age.
• Stupid things we won’t do as we get old.
• Illness denial and death denial.
• Acting our age. 
• Is death to be feared or is it just another stage of life. 
• Slow down and retire or turn 60 and speed up. 
• Multi-generational living, to stay young at heart.
• Staying busy and living long. 
• The scourge on loneliness. 
• Why the LGBTQ Stonewall generation is being forced back into the closet as they seek care in assisted living facilities. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Anti-aging - who needs it?  Surely, striving to master or embrace the aging process is better than trying to defy it?  It is a philosophy we at Live Long and Master Aging share with Tara Gadomski, writer, filmmaker and director of a new short film, Signs of Aging. The story explores, through dark humor, the methods used to sell so-called anti-aging products to older women. A powerful message emerges about the appreciation of life over vanity. In this LLAMA podcast interview, with Peter Bowes, Tara explains her distaste for what she calls the shaming of older people, who’re beginning to show their age.  

In this interview we cover:

• “Shaming” older people and why the term anti-aging should be outlawed. 
• Why some people are made to feel like “lesser human beings ” because they don’t comply with a certain beauty standard.
• Flaws, imperfections, fixes and corrections.  
• Letting go as you get older.
• Embracing and mastering aging rather than trying to defy the process. 
• Telling stories with the benefit of ageing wisdom.
• A story about a fictional saleswoman trying to sell ‘anti-aging’ beauty products to older women.
• The myth of there being “biology to it" - suggesting women are more attractive in their child-bearing years.
• Spoiler alert - we reveal the powerful plot line that exposes the hypocrisy of ‘forever young’ messages in cosmetics advertising. 
• Wrinkles and spots - why we’re lucky to have them.      
• Honoring people who died young. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Living long and well involves focussing on multiple lifestyle practices, including our spiritual awareness. It is a pillar of human longevity that sits alongside a clean diet, vigorous exercise and optimal sleep habits. So let’s meditate. James Brown once thought that his life was “too crazy" to involve meditation, but after a 25-year career in advertising he is now a teacher of the practice and founder of San Francisco based Vedic Path Meditation. In this LLAMA podcast interview with Peter Bowes, James explains his journey from stressed out executive to one of the world’s leading experts in what’s known as a “flow" approach to meditation. 

Check out our home page at LLAMApodcast.com | Twitter: @llamapodcast

In this interview we discuss

• What does the ticking clock mean to you?
• Being blessed genetically and putting in place practices that sustain vitality. 
• Living a frenetic lifestyle and discovering spirituality.
• How does an account executive in advertising and aspiring lawyer become a meditation guru? 
• Becoming a father and responding to new pressures. 
• Embracing the power of unforced smiling. 
• Cleaning a bike chain and the LOL moment that changed James’s life course. 
• What is the practice of flow meditation? 
• Dispelling some of the myths about medication - why and how we do it. 
• The impact of stress.
• What is wide-angle present moment awareness?
• Assessing our habits and putting multi-tasking in persecutive. 
• Focussing and concentrating. What’s the difference? 
• Trying too hard versus a flow experience.  The benefits of effortlessness.
• The stresses of parenting and how to cope. 
• A calling to be on a bigger stage? Ego or nature? 
• Meditating and relationships.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Innovation in human biology is evolving at breakneck speed. Artificial intelligence, data science and pharmaceutical discoveries - combined with a deeper understanding of how the body works at a cellular level - are creating exciting opportunities to extend health span.   Dr. Ron Alfa is Senior Vice President of Discovery & Product at Recursion, a clinical-stage biotechnology company, recently named by Fast Company as one the World’s Most Innovative Companies for 2019. In this LLAMA podcast interview, with Peter Bowes, Dr, Alfa explains Recursion’s mission to create a map of human cellular biology and find novel treatment for the diseases of aging.

Check out our home page at LLAMApodcast.com | Twitter: @llamapodcast

This interview was recorded at TEDMED

In this interview we cover:

• How Recursion is using machine learning and computational biology to change the way drugs are getting to patients from the laboratory.
• Building tools to better understand the safety and efficacy of new molecules for use in the clinic. 
• How drug discovery works and why it is such a long scientific process. 
• How producing a vast amount of data is possible through advances algorithms and machine learning - and why it matters for our health. 
• Is data generated using robotics accurate? 
• How does this data differ from public data sets used widely in research? 
• How Recursion is focussing on reversing cellular aging, or senescence. 
• Defining aging. 
• How import will artificial intelligence be as we move forward with the goal of a longer health span?
• Focussing on solutions that actually reach patients and allow physicians to make better decisions. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

They say sixty is the new forty. Seventy, the new fifty. But what does that mean? We are living longer, but are we living better? Sandra Feaster, a registered nurse and health coach, approaches aging with the same ghusto that an accomplished mountain climber tackles the highest peaks.  She says growing older is an “incredible journey” that embraces the realities of aging while continuing to live life to the full. Along with her husband, William Feaster, MD, Sandra runs the blog T60+, a website dedicated to sharing science-based information about health and wellness, for people turning 60. In this LLAMA podcast interview, with Peter Bowes, Sandra explains her retire, pivot or die philosophy, her disdain for “fake” health news and why she believes we should all lead a more “mindful” life.

Check out our website: LLAMApodcast.com

In this interview we explore:

What it means to live a healthy and active life well beyond 60. 

• Is 60 really the new 40? 
• How the blog T60+ covers the business of health and wellness and separates the fads from facts. 
• When did the realities of aging first resonate with Sandra?
• Tackling and moving beyond cancer.
• How cancer brings your mortality into focus.
• Making the change - delaying the die or exercise regime.
• Why we don’t think about mortality while we’re young. 
• Waiting in line for the next funeral and why we should think about it. 
• Living a more mindful life, at all ages.  
• Moving from nursing to health coaching and blogging and becoming a healthy aging evangelist.
• Making better lifestyle choices based on a lifetime of experience.
• The ah-ha moments that come with healthy eating and exercise.
• Expecting the unexpected to happen, as we age. 
• Aspiring to achieve a long health span as opposed to lifespan. 
• Seeking out reliable preventative health information in the modern world. Who to believe.
• Does the longevity business have our best interests at heart? 
• Why so much emphasis on anti-aging?
• The good, bad and ugly use of social media as we age.
• What gets you up in the morning?  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The Annual Biohacking Conference, hosted by Upgrade Labs, is a mind-boggling, mind-enhancing gathering of people, from all walks of life, who want to live better and longer.  LLAMA’s Peter Bowes attended this year’s event, in Beverly Hills, California, to meet Dave Asprey, the movement’s poster boy for self-improvement, along with some of the conference’s key speakers and exhibitors. In this episode we explore everything from cryotherapy to enhancing neuroplasticity, flow meditation, mitochondrial health and infrared saunas. Dave explains how biohacking has come of age, why he believes he will live to be at least 180 and how he says everyone - not just the rich and famous - could benefit from being in better control of their bodies and biology.  

01:52

Dave Asprey
Founder, Bulletproof

Dave, the original biohacker, explains how and why the practice has come of age and how we can all benefit from it.

"Biohacking is largely the art and science of changing the environment around you, so that you have more control of your biology.”

Also check out: LLAMA episode 65, with Peter’s tour of Upgrade Labs in Santa Monica. 

Martin Tobias: Biohacking to upgrade the human mind and body

12:24

Dr. Barry Morguelan

Chinese energy grandmaster, double board certified gastroenterologist and internal medicine doctor trained at UCLA and currently practicing in Los Angeles. Dr. B, as he is affectionately known, is a force of nature with a mind-blowing story of personal discovery and experience. 

21:54

Dr. Charles Brenner

Head of Biochemistry at the University of Iowa & chief scientific adviser to the Chromadex, a California-based nutraceutical company behind the Nicotinamide riboside (NR) supplement, Tru Niagen. Dr. Brenner updates us on his work understanding NAD and cell metabolism.

Also check out our previous interview: LLAMA episode 53

Charles Brenner: Explaining the science behind “age better” vitamin B3 supplement

26:32

Lauren Hansen, Cryo Science

Learn about the Cryotherapy craze.  Lauren explains the science of exposing the body to subzero temperatures in order to stimulate physical and mental health benefits.

32:26

Dr. Patrick Porter, BrainTap

Dr. Porter hacks the power nap with "brainwave entrainment" technology. Through guided-audio programs and creative visualization processes, an app allows users to "relax, reboot, and revitalize while achieving peak brain performance.” 

41:14

Tom Griffin, Halo Neuroscience

Tom explains the science behind a headset fitted with electrodes that put your brain in a more “excited and malleable state” for an hour.  For athletes, Tom explains that the headset works by applying a small electric current to the part of the brain that controls movement, activating neurons so they fire more often during training.

44:15

Dr. Chris Shade, Quicksilver Scientific

Keto or Kale? If the former is your diet of choice, Dr. Shade explains how a ketogenic diet works and how he has developed a system to hack - i.e. speed up - the process. So what is Keto Before 6?

50:09

James Brown, Vedic Meditation

Step back and go with the flow

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Could listening to music be an important pillar of longevity? If you feel down and listen to a favorite song it can pick you up. Some people say music helps them work harder and the power of music to evoke memories is second to none. There is anecdotal evidence that playing an instrument or enjoying a favorite album can have a lasting impact on our state of mind and, as a therapy, it can help people suffering from the chronic conditions of old age. Brandon Carone is a research assistant in the Memory and Lifespan Cognition Lab at UCLA and research coordinator with Music Mends Minds, a non-profit group that creates musical support group bands for patients with Alzheimer’s, dementia, Parkinson’s, traumatic brain injury, stroke, and for veteran’s with post traumatic stress disorder (PTSD). In this LLAMA podcast interview with Peter Bowes, Brandon explains why music could be much more than a soundtrack to our lives and why, at 21, he has dedicated his life to understanding music as a therapy.

Check out our home page at LLAMApodcast.com
Twitter: @llamapodcast

In this interview we explore: 

• How Brandon’s fascination with the power of music started as a child, covering classic rock songs. 
• The correlation between favorite songs and emotion.
• Why a chemistry major switches to music cognition. 
• Research at the Memory and Lifespan Cognition Lab at UCLA, exploring the difference between younger and older adults and their ability to recall memories. 
• Persuading young people and older adults to take part in memory tests.
• Natural memory loss as we age. 
• How people suffering from debilitating mental conditions respond to music. 
• Anger management and music. 
• How music improves our mood.
• Is there a mathematical formula behind brain behavior?
• Pre-birth memories and how they impact us in later life.
• Funding for research into studies related to music and health.
• The uplifting power of music, at all ages. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

A simple smile, a friendly gesture or an offer of help and friendship, could help us all live longer, healthier lives. International Day of Happiness (March 20) is celebrated by the United Nations as a way to recognize the importance of happiness in the lives of people around the world.  There is scientific data that suggests people who embrace the benefits of a positive attitude, are rewarded with a greater sense of well-being. Catherine Sanderson is a psychologist and professor in Life Sciences at Amherst College in Massachusetts. In her book, The Positive Shift: Mastering Mindset to Improve Happiness, Health, and Longevity, Dr. Sanderson explores the science behind our mindset, and how, she says, anyone can learn to adopt a more positive outlook. In this LLAMA podcast interview, with Peter Bowes, Dr. Sanderson explains how kindness, gratitude and genuine friendships can help promote better physical and mental health. 

Check out our home page at LLAMApodcast.com
Twitter: @llamapodcast

In this interview we explore:

• Why someone who is not “naturally happy” has written a book about happiness?
• What does it mean to be happy?
• Are we genetically programmed to be either happy or more melancholy in our demeanor?
• Does having stress and adversity in life help, ultimately, promote happiness? 
• What if bad things happen? 
• What does MRI data showing levels of "brain activation" tell us? 
• Why do our brains react differently when we’re surrounded by nature?
• How much control do we have over our mindset? 
• Do we spend too little time thinking about and practicing happiness? 
• How powerful is a smile? 
• How a positive attitude can make us feel better and better tolerate adverse experiences. 
• Why are so many people keeping gratitude journals? 
• Bedtime rituals to help us sleep better.
• Does social media make us feel less happy?
• Why Dr. Sanderson says “relationships are the number one best predictor of our happiness."
• Is happiness contagious?
• Why changing our mindset is not easy.
• Scientific data that supports the idea that happier people live longer.
• Why does volunteering make up happier?

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

How many times have you checked your ‘likes' or searched for positive feedback in your social media feed today?  Perhaps you’re the kind of person who always strives to be perfect and feels deflated when you fail to live up to your own expectations. What about being judged by others for not achieving your full potential? Perfectionism, says Dr. Thomas Curran, is “everyone’s perfect flaw.” Dr. Curran, an assistant professor in the Department for Health at the University of Bath, studies the personality characteristic of perfectionism, how it develops, and its impact on mental health. If we all relaxed a bit or stopped being hard on ourselves, would our lives be better?  In this LLAMA podcast interview , recorded at TEDMED, Dr. Curran explains why he believes perfectionism can be harmful and the impact, he says, social media is having on our relationships and self-worth.

Check out our home page at LLAMApodcast.com
Twitter: @llamapodcast

In this interview we cover:

• What does perfectionism mean in the modern world? 
• Why pursuing perfectionism, in today’s culture, is potentially beneficial.
• When does perfectionism begin to be harmful.
• What are the three core elements that make up perfectionism? 
• What are "helicopter parents" and how does their behavior affect their children? 
• Are young people becoming more perfectionistic?
• How did Dr. Curran gather and analyse data for a large study into perfectionism?  
• What is the correlation between depression and perfectionism? 
• How are fundamental changes in society - such as the use of technology - affecting the pressures on young people?
• Why is life today sometimes more about the appearance of perfection than reality?  
• Why do we neglect some things in life that could bring us success and happiness? 
• Social relationships and why they matter.  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Every two seconds, someone in the world will have a stroke. Almost two-thirds of survivors leave hospital with some form of disability.  It is a battle against time to get the most appropriate medical intervention and treatment for stroke victims and every second counts. Viz.ai, a San Francisco-based applied artificial intelligence company, was established by British neurosurgeon Dr. Chris Mansi with the goal of using A.I. to make healthcare work faster and smarter. He was inspired by a patient who underwent a successful brain operation but died because the surgery came too late. In this LLAMA podcast interview, recorded at TEDMED, Dr. Mansi explains why rapid treatment can mean the difference between life and death - and why he believes medical technology is on the cusp of transforming healthcare and dramatically improving the odds of making a full recovery from a stroke. 

Check out our home page at LLAMApodcast.com
Twitter: @llamapodcast

Connect with Dr. Mansi: viz.ai | Twitter | LinkedIn

In this interview we cover:

• The anatomy of a stroke and large vessel occlusions.
• What is mechanical thrombectomy and why is it a “game changer” treatment?
• The devastating impact of strokes and why speed is of the essence in treatment.
• What is Viz.AI
• How does artificial intelligence help save time and save lives.
• The correlation between smoking and lifelong risk of a stroke.
• The symptoms to watch out for that could indicate a stroke.
• Will A.I. ever replace doctors?
• How technology is democratizing health care. 
• Why connecting the right doctors at the right time is crucial to save lives. 
• How is artificial intelligence acquired? 
• How technology standardizes the quality of care. 
• Longevity ambitions and daily rules to live by. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The sudden onset of a common cold or the flu can stop us in our tracks. Seasonal outbreaks of infectious diseases can be both debilitating and irritating, especially for those people who strive to live a healthy lifestyle.  But are they inevitable? Lydia Bourouiba is the director of the Fluid Dynamics of Disease Transmission Laboratory at Massachusetts Institute of Technology (MIT). Her work involves trying to better understand the role that sneezes play in the spread of infections. She focusses, not only on the common cold, but as-yet-unknown diseases that could have widespread and devastating consequences, were they to get out of control.  In this LLAMA podcast interview, recorded at TEDMED, Professor Bourouiba explains how we are all vulnerable to infectious diseases -and probably more than we realize. She also dissects the anatomy the sneeze - how far it can go and how long it can linger.

In this interview we explore:

• How colds are transmitted. 
• Why, no matter how healthy we are, we are all vulnerable to infectious diseases.
• Living in dense populations and the implications for the spread of disease.
• How Dr. Bourouiba studies the mechanics of sneezing. 
• Why droplet size matters.
• What happens during “exhalation events” and why our sneezes are different.
• Why some of us are more likely to transmit infections than others.
• Multi year studies to better understand the spread of colds and flu.
• How far can infectious droplets from a sneeze travel in a train cabin?
• Do masks work to prevent the spread of a virus?
• How big is the threat of another influenza pandemic?  
• How effective are flu vaccines?
• How far should we go to avoid infections ?

Check out our home page at LLAMApodcast.com
Connect with Prof. Bourouiba:  The Bourouiba research group | Bio | TEDMED

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

What if we could screen the body for early signs of disease by swallowing a tiny capsule, packed with futuristic diagnostic tools? Prof. Timothy Lu, a synthetic biologist at MIT, draws on his combined expertise in computer programming, electrical engineering, and microbiology, to envision as an entirely new way of practicing preventative medicine. The idea is that capsules packed with tiny electronics and genetically engineered living cells will eventually be used to spot health problems from inside the gut. Early signs of cancer could be detected without the need for a colonoscopy. In this LLAMA podcast interview with Peter Bowes, recorded at TEDMED, Prof. Lu explains the principles of synthetic biology and why he believes it could help us all live healthier, longer lives.

In this interview we explore:

• What is synthetic biology and how could it help us live better?
• Should we be concerned about “synthetic” biology?
• A new set of diagnostic tools.
• How can human cells do mathematics? 
• Re-wiring the human body, and what that means.
• Preventing and treating disease by swallowing a capsule.
• Detecting early signs of disease
• Engineering the human microbiome.
• Sequencing the bacteria that live inside us and figuring out why they impact us “profound" ways.
• What are the drugs of the future and how will they help us? 
• New strategies to extend health spans.
• Is precision medicine worth the money?
• Developing sensors and memory devices that sit inside the brain.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The Beatles song, When I’m Sixty-Four, pays homage to the aging process and is a tribute to the value of enduring friendships. The light-hearted ditty encapsulates some of the values and aspirations of The SCAN Foundation, which focusses on improving the quality of health and life for older people.  SCAN’s mission is to advance a coordinated and easily navigated system of high-quality services for older adults, preserving their dignity and independence. Bruce Chernof MD currently serves as the Foundation's President and Chief Executive Officer.  In this LLAMA podcast interview with Peter Bowes, recorded at TEDMED, Dr. Chernof explains the challenges for all generations, as they get older, and why he believes embracing the Internet of Things will be crucial to healthy and active aging. He also suggests that the planning process for old age should start much earlier than most people realize, with the sharing economy playing a pivotal role in our way of life. 

In this interview we cover:

• Why Dr. Chernof believes we should stop thinking of aging as “somebody else’s business."
• The SCAN Foundation's new podcast.
• How Gen-Xers and Millennials are “active caregivers” and why they are stressed-out about it. 
• Looking after an adopted grandmother, aged 102.
• Why we need a better word for “care-giving."
• Living in your own home - but for how long? 
• The challenges of the unknown.
• Losing the independence that comes from being able to drive. 
• Devising a plan to maximize mobility as we grow old. 
• Embracing public transport before we are give up the car. 
• Embracing the Internet of Things for healthy and engaged aging.
• How the sharing economy, embraced by millennials, is helping design future living models.
• Living longer but with chronic illness.
• Tackling future health challenges - beyond Alzheimer’s.
• Breaking out of agist thinking. 
• Recognizing the fount of knowledge in older people.
• Devising a plan and aging with dignity.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The cumulative effects of chronic sleep deprivation could be shortening our lives. There is evidence that killer diseases are more likely to occur if we get too little sleep over a prolonged period. One reason why we may not be getting enough shut-eye is excessive noise. Mathias Basner is Associate Professor of Sleep and Chronobiology in Psychiatry at the University of Pennsylvania Perelman School of Medicine and President of the International Commission of Biological Effects of Noise. For the past two decades he has been studying the effects of noise on sleep. It could be the sound of airplanes overhead, the rattling of a heating system or noisy air conditioning that keeps us awake, but research suggests there is a significant connection between noise, sleep, and recuperation.  In this LLAMA podcast interview, recorded at TEDMED 2018, Dr Basner explains the basis for his research and the lifestyle lessons he’s learned through the study of environmental stresses and society’s big problem of sleep deprivation. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

’Tis the season to be stressed, overwhelmed and chronically fatigued. There’s a festive thought. But that feeling of being swamped by to-do lists, meetings, appointments, shopping lists and good old daily chores, is not exclusive to the holiday season. We live connected lives - sharing, posting and liking - often at the expense of more wholesome activities such as spending quality time with loved ones or taking a quiet walk to nurture the soul.  Stress is snapping at the heels of our daily lives and possibly our longevity. So what can we do about it? Dr. Felice Gersh is founder of the Integrative Medical Group of Irvine in Southern California and in this return visit to the LLAMA podcast we take on the worries that overwhelm us. Dr Gersh explains the 'stress response' and the action we can take to better manage our lives in a frenetic world.

• What is stress and what does it do to the body?
• When is stress beneficial? 
• Is fasting is a form of stress that can be helpful to the body? 
• How “just being alive” can be stressful - in a positive way. 
• How the stress response is part of the survival mechanism.
• How the body responds to lack of sleep, worries or overwork. 
• Leaky gut - what’s that?  
• How exercise of diet-induced stress can be positive. 
• How does a state of chronic stress affect human longevity?
• How a hormonal imbalance could cause stress. 
• Show we avoid watching the news to reduce stress? 
• Environmental toxins and strength. 
• Using guided imagery to help reduce stress
• Breathing exercises to reduce stress.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Royce Smith lifts weights with his gym buddies every morning at 5am. Then he goes to work - at one of two companies he runs - and puts in a full day in the office. He competes in obstacle course events like the Spartan Race, has a busy family life and at the age of 76, enjoys the best of health. What is his secret?  In many ways Royce epitomizes a lifestyle that promotes a long health span. In this LLAMA podcast interview with Peter Bowes the California businessman explains how he maintains his rigorous daily routine; why he keeps pushing himself to take part in obstacle course races and how he is inspired to work out alongside younger athletes.  This is the third and final episode in our mini series at Results Fitness, featuring older athletes. 

In this interview we learn about:

• How a 76-year old works six days a week and maintains a vigorous exercise regime. 
• Strength training to maintain stamina 
• How Royce is motivated by his daily routine, rising at 4am to go to the gym.
• Working hard and playing hard 
• Developing the right mental attitude to compete in a Spartan Race. 
• A muti-generational approach: Inspiring younger people to work out hard
• Delaying retirement.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

A decade ago Mark Figearo’s health was in such a perilous state that his doctors feared the worst. With a family history of heart problems the California businessman knew he had to take drastic action to reverse the inevitable decline in his health.  Now aged 68, Mark works out five days a week and is a keen obstacle course racer.  This is the second in our series of interviews at Results Fitness, in Newhall, California, featuring older athletes enjoying the best health of their lives. In this interview with LLAMA’s Peter Bowes, Mark explains his daily regime and shares the secrets behind his journey to optimum fitness and mental clarity. 

In this episode we learn about: 

• How Mark’s awareness of health started as a young boy when his father passed away. 
• The “horror” of the 1950s ‘contractor’s diet.'
• How a health scare ten years ago forever changed Mark’s attitude towards his own health and fitness. 
• How Mark combined his passion for cooking with a new-found appreciation of intense exercise, to get in shape. 
• What happens when life gets in the way of living an active lifestyle. 
• How to overcome a life-long hatred of exercise. 
• How Mark combined his passion for cooking with a new-found appreciation of intense exercise, to get in shape. 
• Still working at 68 and still enjoying it. 
• Bulletproof Coffee and Apple Cider vinegar.  
• Working out with fellow older athletes in a family atmosphere.
• Preparing for a Spartan Race and going back for more. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Rachel Cosgrove was always the coach and mentor that everyone in the gym looked up to. Lean, strong and successful she was the model, middle-aged athlete - a go-getter fitness coach who inspired her clients. But as Rachel turned forty she realized that she no longer had the body of an elite athlete.  The co-owner of Results Fitness in Newhall, California, was putting on weight and becoming a mid-life "statistic”.

What happened next is nothing short of remarkable.

In this interview with Peter Bowes, Rachel opens up about a personal journey that grew out of her 40s fitness crisis. This is the first of three episodes, featuring older adults (between 40 and 80), who find their form and achieve extraordinary results as obstacle course racers. 

In this interview we learn about: 

• Rachel’s love of Spartan races for their unpredictability and unique challenges.
• The mind games Rachel plays to help her survive swimming through freezing cold water. 
• Growing up as part of a family that struggled with weight issues and obesity. 
• Trying different diets and exercise programs and figuring out what works best. 
• The challenges of opening a gym and becoming an expert in the fitness industry. 
• Following the science to devise workout programs. 
• Confronting the time-crunch - the number one objection to exercise. 
• How results can be achieved with just two hours per week of working out. 
• What happened to Rachel when she turned 40. 
• Why living in “moderation” does not work. 
• How easy it is to let things go after achieving personal fitness success and a high-flying career. 
• What Rachel did to get back to her former, super-fit self. 
• How older athletes are achieving peak levels of fitness.
• How becoming a little more selfish and focussing on training as an older adult can reap rewards.
• Prioritizing time for health and fitness. 
• Craving an obstacle course escape from everyday life.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

When Captain Derek Herrera was shot by a sniper in Afghanistan his life was forever changed. Paralysed from the chest down, he left the military to embark on a new career in medical technology.  He devoured the scientific literature to try to find solutions to the chronic disabilities he faced. One problem, neurogenic bladder dysfunction - an inability to control the bladder - mirrored the difficulties faced by millions of people with spinal injuries and other conditions such as Alzheimer’s and Parkinson’s disease. Cpt. Herrera set up a company, Spinal Singularity, and working with doctors, engineers and potential users, he has developed a new device, known as the Connected Catheter, which could significantly improve the lives of sufferers.  In this interview with Peter Bowes, Cpt. Herrera describes the dramatic moment when his life was almost taken away; how he reinvented himself as an entrepreneur and built a company to change the way medical devices are developed.

In this episode we learn about:

• How Cpt. Herrera went from being a “barrel chested freedom fighter" to chronically disabled and wheel-chair bound, when he was shot in Afghanistan. 
• Embracing exoskeleton technology 
• Building on military discipline and culture to pursue a new career in medical devices.
• How personal disabilities - including an inability to control his bladder - led to Cpt. Herrera to develop a new type of catheter.
• How the connected catheter, an electronic device, could prove to be a life-changing advance for people with chronic bladder problems. 
• Current catheterization techniques involve multiple catheters being used every day - the connected catheter can stay in place for up to 29 days. 
• The connected catheter could help people with multiple conditions - from Parkinson’s and Alzheimer’s to traumatic brain injuries and age-related prostate problems. 
• The philosophy of stoicism - focussing on "what you can control and not on what you can’t.”  
• The importance of the "refuge of the mind."

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Advancements in science and technology make it easier and more fulfilling to grow old. But Paul Irving, chairman of the Milken Institute Center for the Future of Aging, says if we are to realize the “longevity dividend,” society must play a bigger role in promoting healthy and purposeful aging. Paul is also the chairman of Encore.org and distinguished scholar in residence at the USC Davis School of Gerontology. He says while medical breakthroughs make it possible to extend lifespans, older people face huge challenges as they embrace longer lives. In a return visit to the podcast, Paul tells Peter Bowes aging should be part of the curriculum for younger people and explains why he believes "intergenerational connection" should be a policy priority for institutions across society and for each one of us individually.

In this episode we discover:

• Why societal support matters for our aging communities.
• When it is good to have an ‘older person in the room.'
• How integrating the generations helps promote healthy aging and wiser younger people
• How Encore.org promotes second acts for the greater good. 
• Why older people are our only growing natural resource
• How social norms should be challenged to benefit young people alongside older adults. 
• Why during these “extraordinary times” there has never been a more important time to "connect generations." 
• Why focussing on people is as important as developing new technology.
• How we could all benefit from more “meaning and purpose.
• The possible benefis of moving away from “age segregated” retirement communities.
• Why educational establishments should embrace young and old students alike.

Listen to Paul’s previous LLAMA podcast conversation:
Episode 10: Promoting purposeful aging & fighting for older people

This is the latest in a series of interviews recorded at the USC Body Computing Conference.  Find out more about the event hereand the USC Center for Body Computing here. Listen to event host Dr. Leslie Saxon’s LLAMA interview with Peter Bowes:  Episode 13: Wearable and implanted technology to promote longevity

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Money worries in old age are an everyday concern for a huge number of senior citizens around the world.  In the United States, one in seven live in poverty. It is an unacceptable number and Dr. Paulo Narciso, Vice President of Impact Areas for the AARP Foundation, is determined to reduce it.  He and his colleagues are using financial technology to help vulnerable older adults save for unexpected expenses,  and Voice Enabled AI to detect social isolation and improve social connectedness.  Dr. Narciso previously founded CloudHealth Asia and, as a serial entrepreneur, he has led several startup ventures. In this LLAMA podcast interview with Peter Bowes, Dr. Narciso explains how even the poorest people in society can save for their old age; why unforeseen circumstances sometimes “spiral out of control,” and how Silicon Valley innovations could provide the best answers.

This is the third in a series of interviews recorded at the USC Body Computing Conference.  Find out more about the event here and the USC Center for Body Computing here.

In this interview we learn about:

• The principles of innovation that are being applied by the AARP Foundation to tackle poverty amongst older people.
• The four pillars of senior citizen poverty

1. Income security - enough money to cover expenses.
2. Housing security - making sure we can “age in place” if desired. 
3. Food security - having access to the right foods
4. Social isolation - increasing social connections and support as we age

• How digital technology and the principles of behavioral economics are being used to help people save, with an app. 
• Living the lives that we want, with a "saving mindset.'
• Why human nature means many people will give money to others while neglecting their own needs."

“"We see that in churches - people will tie 10 percent of their income despite the fact they don't have anything for themselves. They always are willing to give back. We just have to take that mindset and have them pay themselves as well.”

• Why some cultures, outside the U.S., put more emphasis on caring for older adults.
• How Dr. Narciso says his eyes have been opened to the plight of older people since joining the AARP Foundation.
• The resilience of people and Dr. Narciso’s "defining moment" working on a refugee camp during the exodus from Vietnam. 
• Why, as a businessman, Dr. Narciso’s measure of success is based on jobs created rather than profit. 
• Dr. Narciso is also an accomplished athlete and a veteran Iron Man competitor. Why he says the sport is “life changing” and how it mirrors his business life, when “life is not always fun and games."

“What I've learned from Iron Man is, it might look hard now but just keep moving and the next mile might be a little bit better."

At the 2017 USC Body Computing conference LLAMA host Peter Bowes moderated a session focussing on better outcomes for older people through the use of digital technology. Watch the video here.

Related LLAMA podcast interviews: 

• Lisa Marsh Ryerson (Ep.35) - President, AARP Foundation

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Maureen Feldman runs the Motion Picture & Television Fund’s (MPTF) Social Isolation Impact Project. The program brings together volunteers and entertainment veterans who are in need of some company. It may come as a surprise, but even in Hollywood, loneliness is at chronic levels amongst older adults. The project is working to unite isolated senior citizens with younger, like-minded professionals through its Daily Call Sheet. The service helps older film industry members make new friends. In this LLAMA podcast interview with Peter Bowes, Maureen explains why most of us are ignoring a vital pillar of healthy aging; how we should focus on social connections early in life, to avoid loneliness in old age; and what the MPTF is doing to make sure the oldest members of society are never without friends. 

This is the third in a series of interviews recorded at the USC Body Computing Conference.  Find out more about the event here and the USC Center for Body Computing here.

In this interview discover:

• Why people in high pressure, demanding jobs, such as in the entertainment industry, often find themselves lonely and isolated in old age. 
• Why looking after ourselves physically, sleeping enough and preparing financially for our retirement, is not enough. 

”People are not necessarily prepared for aging when it comes to social connections.”

• How older people can suddenly feel isolated in the home they have lived in for decades. 
• How growing to a great age and outliving our friends is a recipe for acute loneliness. 

"I have reached out and I look at everyone I meet as an opportunity for a social connection...it’s it's not that hard you just have to be present and available.”

• Why intergenerational programs are so valuable to reduce social isolation.
• It is never too late to make new friends. 
• How the MPTF’s Daily Call Sheet is helping the aging Hollywood community find new meaning in their lives. 
• How volunteers are teaching older adults to use mobile technology to help them integrate with the outside world. 

"This is a very high touch, low cost way to reach a lot of people and add some joy and create some quality at the end of someone's time.”

The Live Long and Master Aging (LLAMA) podcast hacks the aging process. Peter Bowes interviews world-renowned scientists, future thinkers and biohackers, all of whom have a common goal of figuring out how we can live longer and healthier. We also talk to inspiring individuals who have already mastered the aging process. The LLAMA philosophy is that there is much can do to extend our natural health span or the length of time when we enjoy optimal health. We talk a lot about food, fasting, fitness, the brain and good fortune.

If you enjoyed this episode please rate and review us here.  

As ever, thank you for listening. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Dr. Scott Kaiser is a practicing geriatrician at the Motion Picture & Television Fund (MPTF), a charitable organization that provides services, support, and assistance to the Hollywood community. As the MPTF’s Chief Innovation Officer, Dr. Kaiser is committed to creating communities that support peoples' ability to live and age well, with dignity and purpose. A passionate advocate for the growing population of older adults, Dr. Kaiser bemoans what he calls “rampant agism within the medical community,” and the “institutional bias” he says he has encountered doing his job. In this LLAMA podcast interview with Peter Bowes, Dr. Kaiser explains his unique role, working with members of the entertainment community, and why he is privileged to hear “the best stories" from his patients. 

This is the third in a series of interviews recorded at the USC Body Computing Conference.  Find out more about the event here and the USC Center for Body Computing here.

The Live Long and Master Aging (LLAMA) podcast hacks the aging process. Peter Bowes interviews world-renowned scientists, future thinkers and biohackers, all of whom have a common goal of figuring out how we can live longer and healthier. We also talk to inspiring individuals who have already mastered the aging process. The LLAMA philosophy is that there is much can do to extend our natural health span or the length of time when we enjoy optimal health. We talk a lot about food, fasting, fitness, the brain and good fortune.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Sean Vassilaros is the Chief Operating Officer with THREAD, a virtual research platform that helps researchers gather data for clinical research.  The company has developed the concept of a virtual visit.  It enables researchers to connect with patients and volunteers via a video chat instead of requiring them to attend on-site clinic visits. The idea is that it saves time and money over conventional ways to carry out research, but still produces reliable and secure data.  In this LLAMA podcast interview, Sean explains how the platform works and his “lofty” goal of helping researchers provide answers for "every biological question."

NOTES AND QUOTES

Connect with Sean and THREAD: Website | Twitter | email 

"One of the things that we firmly believe is that we have the ability, we as humans, have the ability to answer every human biological question at some point."

In this interview we discover: 

Why Sean believes the time is right to answer every biological question. 

• Is it possible to use computers to diagnose every health condition?  
• How reliable is patient entered data?
• How are clinical trial volunteers encouraged to remain engaged in the study? 
• How THREAD technology was used in a study led by the USC Center for Body Computing to measure what personal traits determine whether a Marine makes it through the grueling Marine Corps Basic Reconnaissance Course.  Read more. 

"Our goal is to make sure that as researchers you have at your finger tips, at your disposal, more information than you’ve ever had so that you can make better claims than conclusions.” 

This interview was recorded with our friends at the USC Body Computing Conference.  Find out more about the event here and the USC Center for Body Computing here.

The Live Long and Master Aging (LLAMA) podcast hacks the aging process. Peter Bowes interviews world-renowned scientists, future thinkers and biohackers, all of whom have a common goal of figuring out how we can live longer and healthier. We also talk to inspiring individuals who have already mastered the aging process. The LLAMA philosophy is that there is much can do to extend our natural health span or the length of time when we enjoy optimal health. We talk a lot about food, fasting, fitness, the brain and good fortune.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Carol Rosenstein is the cofounder of Music Mends Minds. Launched in Los Angeles, with her husband Irwin, the nonprofit organization creates musical groups for people with Parkinson’s, Alzheimer’s and similar disorders..

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Tracy McCubbin helps others declutter for a living. As we get older, many people find it hard to let go of stuff they've accumulated over the decades. But letting go is often a transformational experience. Tracy, through her Los Angeles-based company, dClutterfly, helps retirees prioritize essential items for the next phase in their lives, and advises the elderly on parting ways with items that simply no longer add value to their days. In her upcoming book, The Clutter Code, Tracy describes the emotional blocks that prevent people from decluttering their lives, and how to overcome these obstacles. She also discusses the practicalities of clearing our homes of mementoes, furniture, bric-a-brac, books and photos. In this LLAMA podcast interview with Peter Bowes, Tracy explains the importance of simplifying our lives and why there is a correlation between healthy aging and living in a clutter-free world.

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DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

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Suzi Grant personifies the art of growing old with purpose and a huge sense of fun. At 68 she is an Instagram star, a successful blogger and poster girl for healthy aging. 

A formerly hard-drinking, chain-smoking radio and TV journalist, Suzi traded her unhealthy habits for an alternative way of living as a nutritionist and writer.  Based in Brighton in the UK, she blogs at Alternative Ageing and is the author of several books.

In this LLAMA podcast interview with Peter Bowes, she explains the inspiration behind her new career; her passion for taking part in Instagram Lives and creating YouTube videos; how she believes her memory has improved through regular blogging, and the lifestyle secrets behind living each day with vigor and vitality. Suzi and Peter also share stories about their shared love of broadcasting, fasting, exercise and purposeful aging.

Learn more about Suzi at the LLAMA podcast website.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Spartan Races have become a worldwide phenomenon. Weekend warriors and elite, endurance athletes go into battle on military-style obstacle courses, mostly just for the fun of it. The Spartan Race is the brainchild of Joe De Sena, a former Wall Street trader who was so bothered by his sedentary lifestyle, that he gave up his lucrative career to spend more time outside. He quickly became addicted to adventure, and activity that worked his body to exhaustion. An entrepreneur from an early age, Joe made good money from his desk job, but he always yearned for a life of physical challenges. After competing in ironman triathlons and other ultra endurance events, he created the Death Race, followed by the Spartan Race, an event that is more accessible to the masses. After a difficult start, the race has grown into a global challenge, across 40 counties, with millions taking part every year. Joe is the author of Spartan Up!: A Take-No-Prisoners Guide to Overcoming Obstacles and Achieving Peak Performance in Life - and he hosts the Spartan Up podcast. In this LLAMA podcast interview, with Peter Bowes, Joe explains why he believes humans need to sweat and challenge themselves. He also discusses the mental and physical benefits of enduring a reasonable amount of pain, and why it's so important to step outside of your comfort zone.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Monthly menstrual cycles provide hormones a woman’s body needs regularly to stay healthy and keep her immune system strong. But what happens when that process is interrupted? Scientist, author and naturopathic doctor, Lara Briden believes hormonal birth control can have tremendous effects on the body's longterm health and ability regularly to produce hormones like estrogen and progesterone. Halting the body's natural monthly menstrual cycle with hormones is akin to castration, Lara believes. In this LLAMA podcast interview with Peter Bowes, Lara, author of Period Repair Manual, describes what happens to a woman's body when she is taking hormonal birth control pills, and what this could mean for immune and brain health later in life. She also discusses birth control alternatives, and what she does to keep her body's sleep cycle on track and lead a healthy life. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Dr. Daniel Amen is a polarizing figure. He is hugely popular, with a string of successful clinics, books and TV shows - but derided by some of his professional peers. The founder of mental and physical health centers, Amen Clinics, he believes traditional psychiatry is missing an important component. Dr. Amen says many psychiatrists overlook an extremely important tool of thorough brain analysis. A double board-certified psychiatrist and clinical neuroscientist, he uses single-photon emission computerized tomography (SPECT) scans - which measure brain activity - to address issues like depression, anxiety and attention deficit disorder. In this LLAMA podcast interview with Peter Bowes, Dr. Amen explains his idea of a brain-healthy lifestyle - and why it is key pillar in the quest for a long health span. He also answers critics who have suggested that his methods lack scientific validity.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Imagine being able to build as much muscle in one 12-minute workout as during four, hour-long sessions; or forgoing months of physical therapy for an injury treatment plan lasting just a few days. Enter the world of biohacking and Bulletproof Labs in Santa Monica, California. The machines inside the futuristic fitness and healthcare center may look like something out of a science fiction film, but they were built, according to CEO Martin Tobias, around the practical concept of becoming as healthy as possible with minimal effort. Bulletproof Labs describes itself as "the world’s first human upgrade center for the mind and body.” it offers interventions such as cryotherapy, light therapy, atmospheric cell training, adaptive resistance technology and a gym-busting, computerized curling device called a Cheat Machine. In this LLAMA podcast interview with Peter Bowes, Martin explains the mission and technology behind Bulletproof Labs and his personal passion for hacking his way to a younger cellular age.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

A new documentary film focusing on the “intimate memories and inspiring personal histories” of some remarkable older adults, recently premiered in California. Lives Well Lived features the stories of forty people who share their wit and wisdom with remarkable candor. Filmmaker Sky Bergman, a professor of photography and video at Cal Poly State University, San Luis Obispo, says she was inspired to make the film by her Italian grandmother, who still enjoyed exercising and cooking as a centenarian. The film is both inspiring and sobering, with honest accounts of the aging process. In this LLAMA podcast interview, with Peter Bowes, Sky reveals the common traits of people who achieve a great age with dignity, vitality and optimism. She also explains why aging should be cherished rather than defied or despised.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

When Phil Riley caught a candid glimpse of himself in a hotel mirror, it was a wake-up call. He says the realization that he was clinically obese was one of his most "unnerving experiences." Health and fitness had never been a top priority for the British broadcast industry executive - but Phil knew he had to change. He had also been hard by the loss of some long-time friends, at a relatively young age. It was the start of a journey that saw Phil delve into the data surrounding premature death and the actions he had to take to get his own life in order. The result is a remarkable physical transformation and an analytical book, The Life of Riley, outlining the lifestyle changes that made it possible. In this LLAMA podcast interview, with Peter Bowes, Phil explains his new found love of intermittent fasting; his nerdy fascination with food, feeding times and spreadsheets; and the driving force behind his goal of living to 90.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

What makes us tick? Our in-built clock - the circadian rhythm - plays a huge role in human longevity. Getting an appropriate amount of sleep while the sun is down has tremendous positive effects on our bodies, according to Dr. Felice Gersh, gynecologist and founder of the Integrative Medical Group of Irvine in Southern California. Sleeping in the dark keeps our body's 24-hour internal clock on track and helps regulate our hormones and metabolism. Still, many people wind up staying up later than they planned, while others work night shift hours, which disrupts our internal clock. In this LLAMA podcast interview with Peter Bowes, Dr. Gersh describes what we can do to regulate our master clock when it is thrown off by lack of sleep or unconventional routines; why it matters for healthy aging and how our meal times could be the solution to night shift fatigue. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Dr. Larry Senn, an 82-year old businessman, often completes a sprint triathlon on a Saturday, as part of his exercise regime. He took up the sport at the age of 70. The founder of the global culture-shaping firm, Senn Delaney, believes that to be a good leader, you first have to take care of yourself. He practices what he preaches, although Larry shares his wisdom with a twinkle in his eye and is far from preachy in his approach. Sometimes referred to as the Father of Corporate Culture, Larry works with Fortune 500 companies and business leaders around the world, improving mindsets and creating high-performance teams. In this LLAMA podcast interview, with Peter Bowes, Larry discusses his new book, The Mood Elevator, describes a lifestyle that embraces a full working week, regular daily exercise, long-distance travel and an active family life. He even finds time to go skydiving with his 18-year old son.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

We may not have completely mastered aging just yet, but we might be in the process of truly delaying it, according to Dr. Eileen Crimmins. The AARP Professor of Gerentology at the University of Southern California Leonard Davis School of Gerontology studies health and mortality rates and global aging. After analyzing national health data in the US, Dr. Crimmins and her colleagues concluded something quite inspiring - Americans are biologically younger now than they were 20 years ago. “The biological age has dropped remarkably,” she says. Heart-disease deaths have significantly decreased and cancer rates are beginning to fall. However, there is much to be done if you'd like not just a longer life, but a healthier one. In this LLAMA podcast interview, with Peter Bowes, Dr. Crimmins outlines what lifestyle changes are most likely to have a real, positive impact on the quality and length of your life, and what behaviors likely improve nothing at all.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The extraordinary power of fasting evokes many human emotions, from visceral opposition to a religious adherence to the age-old practice. Going without food can be dangerous and could lead to death under certain circumstances. But medically supervised fasting regimes or diets based on calorie restriction and time-restricted feeding, could be helpful in treating common ailments and even chronic diseases. The topic is explored in great depth in ‘Fasting,' a new documentary by Doug Orchard, a filmmaker, cinematographer and self-experimenter. The film examines seven different methods of fasting and weighs the pros and cons. In this wide-ranging interview Doug explains his respect for fasting; how he has come to understand the limitations of the practice and why he believes in a strict daily feeding regime. He also discusses his own bodily transformation and dawn-to-dusk adherence to exercise, movement and meal windows.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Fitness after fifty was never something that occurred to veteran financier James P. Owen, during his hectic life in corporate America. But when he turned seventy, the former Wall Street rainmaker and author of the best-selling book, Cowboy Ethics, had an epiphany. He discovered he could move. Jim founded the Center for Cowboy Ethics and Leadership to spread the message that “we can all be heroes in our own lives,” but it was not until relatively late in life that he says he discovered his true purpose. Over the past seven years he has transformed his life, applying his much-lauded ‘rules of the west’ to a disciplined fitness regime. The result is a body and lifestyle that defies his age and a new book, Just Move: A New Approach to Fitness After 50, in which Jim shares his wisdom. In this LLAMA podcast interview he explains how “fighting off old age” involves shadowboxing, weightlifting, walking and a focus on "functional fitness."

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Living longer and healthier means embracing a third chapter in life as “fabulously” as possible, says Tricia Cusden, a former management training consultant who has built a successful new business, in her late 60s. When she and her daughters sat down for dinner in Los Angeles last week, they had to pinch themselves, after realizing they were living Tricia’s dream. Five years ago, instead of retiring, she launched Look Fabulous Forever, a makeup brand designed for women aged over-55. It has grown into a multi-million pound family business, with millions of YouTube views for makeup tutorials. Promoting Tricia’s product range in Hollywood is a surreal highpoint in the London businesswoman’s inspiring journey. She is also the author of Living the Life More Fabulous, a guide to “feeling great whatever your age." In this LLAMA podcast interview Tricia explains her belief that we should “go into a period of renaissance rather than retirement,” and feel younger as we explore new adventures, later in life.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

There has been a lot of buzz recently surrounding a new supplement that could boost our energy levels as we grow old. It is a recently discovered form of vitamin B3 and has been widely touted as a possible tool to enhance the aging process. We are going to take a deep dive into what it is and how it works. Nicotinamide riboside (NR) is converted by the body into nicotinamide adenine dinucleotide (NAD) which is an essential molecule found in every living cell and plays a significant role in energy production, regulation of the circadian rhythm and cognitive function. Dr. Charles Brenner is one of the world’s leading authorities on the biochemistry behind NR and its potential to extend life in some organisms. Dr. Brenner is the Roy J. Carver Chair and Head of Biochemistry at the University of Iowa and founding co-director of the University of Iowa Obesity Initiative. He is also chief scientific adviser to Chromadex, a California-based company behind the NR supplement, Tru Niagen. In this in-depth interview, Dr Brenner explains the significance of NAD and why he believes supplementation with NR could help us "age better." He also elaborates on why he refuses to describe NR as “miraculous or magic” and explains why he is uncomfortable with the often-heard expression, 'anti-aging,’ in the marketing of human longevity.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The specter of so-called fake news is omnipresent these days. Headlines are scrutinized more than ever. We can never be quite sure that the facts behind them are actual facts or a distorted truth. It is a worrying trend that has plagued the world of health news for some time. Sifting through the plethora of new studies, to find reliable and useful information, can be daunting and demoralizing. Dr. Sara Gorman is a public health and mental health expert, based in New York. Her first book, Denying to the Grave: Why We Ignore the Facts That Will Save Us, explores the psychology behind irrational health beliefs and decisions. It also includes tips for the general public on how to discriminate between valid and invalid science. Sara is also a co-founder of Critica, a community committed to making rational decisions about health and security. In this in-depth interview, recorded at TED MED 2017, in California, Sara explains why we often have difficulty challenging long-held beliefs about our health; the tactics she uses to filter new scientific studies and how she views claims about nutrition habits that are tied to longevity claims.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Harith Rajagopalan is a medical doctor, entrepreneur and co-founder of Fractyl, a biotechnology company based in Lexington, Massachusetts. Fractyl's stated mission is to solve the global epidemic of type 2 diabetes, a disease that stands in the way of a long and healthy life for so many people. Dr. Rajagopalan’s work focuses on a better understanding of the root cause of the disease and how diet-related damage to the inner surface of the small intestine leads to insulin resistance. The company has developed a clinical procedure to rejuvenate the duodenal surface, which helps patients reverse or even halt the progression of their diabetes. In this in-depth interview, recorded at TEDMED, Dr. Rajagopalan explains how the minimally invasive treatment works and how it could give hope to millions of patients who view diabetes as a progressive condition. He shares his evolving understanding of dietary practices, such as fat consumption and fasting - and explains why birthday cake should play a role in our lives.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Respect for the elderly knows no bounds, as Jo Schneier, CEO at Cognotion, eloquently explains: "It's so easy to look at people and prejudge them and to think, 'I just see an old person.’ I don't see the child, as she was growing up, or the teenager or the woman who got married or the man who got the job promotion or traveled overseas.” In front of us are people whose lives have been beautifully lived, says Jo, whose work focusses on developing digital education programs to train caregivers for aging populations. Based in New York, Cognotion offers interactive learning platforms for a range of jobs, including nurses and home health aides. In this interview, recorded at the recent TED MED conference in La Quinta, California, Jo explains the philosophy behind a learning technique that combines cognition and emotion; how the company searches out society’s “untapped potential” to work with a “demanding” population; and why he lifts weights, in mid-life, to nurture his own longevity.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Rangan Chatterjee is a medical doctor, best known in the UK as the star of Doctor in the House, the BBC series that helps restore people to optimal health. After two decades of practicing medicine, Dr Chatterjee is on a mission to replace pills with "lifestyle prescriptions. He believes that people are needlessly suffering and that health care professionals should put more emphasis on preventing chronic, lifestyle-related conditions though behavioral changes. The author of The 4 Pillar Plan says the secret to a longer, healthier life lies in relaxation, sleeping, movement and a carefully chosen diet. He also acknowledges that healthy eating has become “incredibly complicated.” In this in-depth interview Dr Chatterjee explains how modern lifestyles are negatively impacting our health; why his personal longevity goal involves the ski slopes of the French Alps and the difference a ’switch-off' routine makes to restful sleep.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

When Santino Panico, once a rising sports star, realized that he would never achieve his dream of becoming a big-time American football player, he took a close look at his diet. Poor health had forced him to give up the sport that he loved - including a place on the team for the University of Nebraska - even though he thought he was doing everything right in the kitchen and the gym. Panico went from devouring copious amounts of steak and eggs to a plant-based diet that bemused and confused his Italian, food-loving parents. Now, as a first-time film-maker, he tells the story of his journey to "rediscover the athlete within,” in the documentary, From The Ground Up. The film features leading athletes talking about their own adherence to a dietary lifestyle that many of their contemporaries shun. In this in-depth interview Panico re-lives the days when he was booed by fans and forced to give up his dreams; he explains how he came to the conclusion that the conventional wisdom about developing a strong body is “nonsense,” and talks, in emotional terms, about achieving "the why" when living for longevity.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

 Dr. Valter Longo returns to the podcast to talk about his new book, The Longevity Diet. The Italian scientist is professor in Gerontology and Biological Science and director of the Longevity Institute at the University of Southern California (USC) in Los Angeles.  The book, already a best-seller in Italy, is the result of decades of research - including laboratory and field studies - into the mechanisms behind the aging process.  The diet is based on a low protein and fish-based plan with periodic periods of fasting. In this in-depth interview Dr. Longo explains why he believes it is the optimal regime to live a long and healthy life; how getting to the age of 110 is a realistic goal, and why the word ‘intermittent’ should be banished from conversations about diet.  

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

For many of us, January means a new start, with fresh energy and vigor to live the best life possible. The first few days of the year come with a sense of purpose that helps put our lives into perspective. Fitness coach Alwyn Cosgrove sees it as a “magical” time, when people can change and create new habits.  Alwyn was born in Scotland and initially exposed to fitness training through competitive martial arts.  He went on to study Sports Performance at West Lothian College and achived an honors degree in Sports Science from the University of Liverpool. He is a cancer survivor and the co-owner of Results Fitness in Santa Clarita, California, which has twice been named one of America’s Top Gyms by Men’s Health Magazine.  In this in-depth interview Alwyn explains his scientific approach to fitness and his insatiable appetite for new, data-driven studies on exercise. He also shares his renewed appreciation for the simple but “amazing" things in life, after being re-born, cancer-free.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

If there were such as thing as the Fountain of Youth, Dr. James Hamblin, senior editor at The Atlantic, must have been drinking from it all his life. In the real world, the 35-year old doctor-turned-journalist, shrugs off his youthful appearance as a family trait. When asked about his boyish looks, the host of the video series, If Our Bodies Could Talk, responds without hesitation. He is used to answering questions. After training as a radiologist and dabbling in improv comedy, James realized that he preferred talking for a living than practicing medicine. He is now known as the doctor who offers “off-beat perspectives” on health matters, through his writing and video series. In this interview, James shares his disdain for news cycles and enthusiasm for a plant-based diet. He also discusses his frustration with the medical profession and suggests family doctors would serve their patients better if they had an active Instagram account.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

 Dr. David Albert is a visionary physician and innovator in the field of digital health.  As an entrepreneur he has developed medical products and nurtured new technologies over the last 30 years. A graduate of Harvard College and Duke University Medical School, Dr. Albert has founded three tech companies, InnovAlarm, Lifetone Technology and AliveCor  his most recent endeavor, which has developed the mobile ECG or electrocardiogram sensor. The Kardia mobile device, which is aimed at everyone, detects and analyzes heart rhythm with a simple sensor and mobile app. The ECG - sometimes referred to as EKG - is the electrical activity of the heartbeat and the data could help to detect signs of heart disease.  In this in-depth interview, recorded at the USC Center for Body Computing Conference, Dr Albert explains his vision for future medical technology, which he says has the potential to impact disease, aging and enhance human longevity.  

SHOW NOTES
 
 David Albert (@DrDave01) is the founder and Chief Medical Officer at AliveCor (@AliveCor ‏). 

 LLAMA host Peter Bowes met David at the 2017 USC Center for Body Computing Conference, where he was presented, by Dr Leslie Saxon, with the inaugural USC CBC Digital Health Innovator Award.  

 Watch videos from the conference here.

 “Peace of mind is often times as important as a piece of medical information. Anxiety and stress impact our lives, impact our longevity.”

 "I shame my children in their work out habits and that's had a positive impact on them. I think we can all have an impact on our fellow man and whether or not I live a year longer or not, the quality of my life will be better and I think that's key. You know it's not just longevity it's quality."

 “You can have a direct impact with your lifestyle on your longevity and on your functional longevity, that is your quality of life, at an older age."

 “Affluence impacts longevity anywhere in the world so if you are more affluent you will live longer. Now that's the kind of discrimination that I think we have to work to fight."

 "Knowing facts is not nearly as important as being able to adapt to a changing environment and being able to continuously learn."

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Dr. Michelle Longmire is a Stanford-trained dermatologist, accomplished athlete and CEO of the digital health platform, Medable. The Palo Alto, California-based company is transforming the way clinical trials are performed by opening up the process to everyone.  Through its technology and “direct-to-patient” approach, Medable is making it possible for researchers to capture data that would otherwise be lost to the scientific process. This includes environmental factors and the continuous measurement of a person’s physiology, to create a road map of their lives.  In this in-depth interview, recorded at the USC Center for Body Computing Conference, Michelle explains how patient-generated data has the power to radically improve healthcare delivery, clinical research, and personalized and predictive medicine. She also reveals how running every day helps her to manage her company and why she heeds her grandmother’s advice to sleep on her back.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

"Alzheimer's disease, a devastating disease that affects the cells of the brain, is now regarded as the major form of old age “senility,” said President Ronald Reagan in 1983, as he designated November as National Alzheimer's Disease Awareness month.  "Because there is an association of dementia with aging and because Americans are living longer, the numbers affected by this disease will continue to grow,” he added.  A decade later Reagan was diagnosed with the disease and November is still recognized as a month to focus on a condition that affects over 47 million people, worldwide.  Dr. Lon Schneider (@LonSchneiderMD) is professor of psychiatry, neurology, and gerontology at the Keck School of Medicine of the University of Southern California. He is also the director of the California Alzheimer's Disease Center and a longtime researcher into the disease for which there is no cure. There has been much progress since Reagan’s time and Dr. Schneider is currently studying ways to halt the progress of Alzheimer’s disease, decades before it begins. In this in-depth interview, he explains how an intervention 10 to 12 years before Alzheimer’s manifests, it may be possible to stop the diseases in its tracks; why an understanding of our genetics could be vital to stave off the disease and how people can volunteer to be part of this long term study. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

We are living longer and the pace of population aging is growing faster than ever. Globally, the proportion of people over 60 years old will almost double by 2050. Aging comes with many challenges - from health and wellbeing to housing, mobility and maintaining social networks. The AARP (American Association of Retired Persons) caters for the social welfare needs of nearly 38 million Americans. Lisa Marsh Ryerson is president of AARP Foundation, the organization’s charitable affiliate. The foundation focuses on support programs and initiatives to help older people, especially those living in poverty. It is currently collaborating with a pilot program to connect senior citizens with transportation. In this in-depth interview, recorded at the University of Southern California’s annual Body Computing Conference, Lisa explains how she has been inspired by her work to help others achieve purpose and happiness; why ‘elderly’ may not be the best word to define older adults; what it means to be an "intentional neighbor" and why she believes a mindful attitude helps in planning for the 100-year life.

Show notes and links

Lisa discusses a pilot project announced at USC Body Computing Conference to study how the health of older populations can be improved by helping them become more mobile. The pilot is a collaboration with the insurance company UnitedHealth and the ride sharing company Lyft.  

What is AARP Foundation?

Related past episodes

34: Dan Trigub - Lyft's plan to reimagine transportation to improve healthcare for older people
11: Edith Avise - Sharing longevity secrets at 100 years of age and tackling the challenges of a life without a car. 
10: Paul Irving

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Older adults often miss medical appointments because they are unable to get the hospital or doctor's office. A lack of transportation has been shown to be a major factor.  The inability to get around also leads to social isolation and loneliness and could contribute to the failing health of many senior citizens.  In the age of on-demand car services, younger generations take for granted the ability to hail a relatively cheap ride, but older people are less likely to embrace the technology that makes it possible. This may be about to change, with an inspiring collaboration between several organizations with an interest in helping older people get around. The ride sharing company Lyft has teamed up with the University of Southern California (USC) Center for Body Computing and the AARP Foundation to pilot a program to connect senior citizens with transportation. With a $1 million grant from the insurance company UnitedHealth, the aim is to study how the health of older populations can be improved by helping them become more mobile. Lyft's Dan Trigub (@datrigub) works on projects to develop the company's healthcare partnerships.  In this in-depth interview he explains how the pilot scheme will work; why he views Lyft as more than just a service to take millennials to bars; how driverless cars could help older people with physical challenges; and why he believes his 3-year old son will never know what it means to have a driving license.

More information
Pilot project announcement at USC Body Computing Conference

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Brianna Stubbs (@BriannaStubbs) has been a competitive athlete all her life. At the age of 12, in 2004, she became the youngest person to row across the English Channel.  She went on to win a gold medal with the GB Rowing Team at the 2016 World Rowing Championships and twice rowed for Oxford in the Women’s Boat Race against Cambridge.  Alongside her athletic endeavors, Brianna pursued an academic career, completing her PhD in metabolic biochemistry at Oxford. She is particularly interested in the effects of exogenous ketones on human performance. Earlier this year she joined the San Francisco biohacking company HVMN to pursue her research into the science of human enhancement.  In this in-depth interview Brianna breaks down the theory and shares her understanding of ketone supplementation to promote physical performance. She also describes a day in the life of a semi-retired British athlete, discovering a new life and occasionally fasting in sunny California.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Dr. Joel Kahn has treated thousands of acute heart attacks during a career spanning more three decades.  A graduate of the University of Michigan Medical School, Dr. Kahn has served as Clinical Professor of Medicine (Cardiology) at Wayne State University School of Medicine since 1993. Once a traditional doctor using traditional techniques, he now applies a holistic approach to health care, believing that many chronic diseases could be prevented through changes in lifestyle, with a plant-based diet at the core of his approach to wellbeing.  In this in-depth interview Dr. Kahn explains his theory that the best recipe for good health is a lifestyle “extreme in diet, moderate in exercise and abundant in love.” And with heart disease standing as the world’s leading cause of death, he also plunges into the debates surrounding high fat diets and confusing health messages in the media.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Dr. Andrius Baskys (@MindThisMind) adopted a lifestyle of calorie restriction because he wanted to improve his health as a middle-aged man. The Lithuanian-born psychiatrist and neuroscientist studies aging and interventions to reverse it. A prolific writer and former clinical professor of health sciences at the University of California, Riverside, Dr. Baskys currently practices as a gero-psychiatrist, treating mental disorders in the elderly. He permanently restricts his caloric intake because he believes it will optimize his everyday health and chances of living a long, disease-free life. In this in-depth interview he describes his daily regimen, its apparent health benefits and the restrictions it imposes on his active lifestyle. He also discusses the practical implications of a dietary practice that involves careful measuring of his food, at every meal. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

When Allison Melody lost her parents to cancer it had a profound and life-changing effect on her attitude towards food and the healing power of nutrition. In her early twenties she says she had "no awareness of health,” but was moved to dedicate her life to finding a better way to heal. A film-maker and entrepreneur she formed Holistic Voice, a multi-media production company focussing on diet, exercise and alternative healing modalities. Allison co-hosts, with Suzy Hardy, the Food Heals Podcast (@FoodHealsNation), which brings together experts in the fields of nutrition, health and healing. In this in-depth interview, recorded at the recent Podcast Movement gathering in Anaheim, California, Allison reveals her personal longevity goals and explains how she handles skeptical voices as she pursues a life of optimum health.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Bob Tygenhof is a 68-year old gym rat and health professional. A former advertising industry executive, Bob pursued a second career as a certified fitness specialist and nutritionist with the Integrative Medical Group of Irvine, California. A long-time exercise devotee, Bob follows a rigid program of strength and aerobic training, in between coaching patients on personalized programs. Working alongside doctors, he also overseas patients following a Fasting Mimicking Diet (FMD), called ProLon, for body weight management and longevity. The Irvine medical practice was among the first to embrace the diet, developed by Dr. Valter Longo at the University of Southern California (USC). LLAMA host Peter Bowes took part in an early clinical trial and was one of the first human guinea pigs to try out the FMD. He discusses it in detail with Dr. Longo in LLAMA episode 01. In this in-depth interview, recorded at the 2017 Podcast Movement gathering in Anaheim, California, Bob Tygenhof explains his motivation for a relentless exercise program and devotion to a lifestyle focussed on longevity. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Problems associated with the aging heart could be reversed by infusing the organ with a type of cell taken from a young heart. According to a study published last week in the European Heart Journal, elderly rats injected with a specific type of stem cell showed a significant improvement in their health and vitality. The cardiosphere-derived cells helped reverse signs of aging in animals with an average age of 22 months, which is considered old for a rat. They were more agile and even showed better hair growth than animals in a control group. In this in-depth interview, Dr. Lilian Grigorian, the study’s co-primary investigator at the Cedars-Sinai Medical Center Heart Institute in Los Angeles, explains how the research was carried out, and why some of the results came as a surprise. She says the “incredibly motivating” findings could have “exciting” implications for human heart health and longevity within the next ten years.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Floyd Norman is busier than ever. He is 82 and still working at the job he started in the 1950s. A cartoonist all his life, Floyd enjoyed a hugely successful career creating some of Disney’s most iconic characters. As a young cartoonist he was handpicked by Walt Disney to be part of the team behind The Jungle Book. He also worked on classics such as Sleeping Beauty, One Hundred and One Dalmatians and Mary Poppins. Later, at Pixar, Floyd brought his creative flair to Toy Story 2 and Monsters, Inc. But Disney’s first black animator says he was “pushed out” of the job that he loved when he reached the traditional retirement age. With cartoons and a love of animation in his blood, he refused to accept that his career was over. He returned to work and has since been honored with the title, Disney Legend, in recognition of his extraordinary contributions to The Walt Disney Company. In this in-depth interview Floyd explains how being busy in his 80s helps him stay young; how, as an “old codger,” he reinvented himself by learning to use digital editing software; and why “not clinging to the past” is the key to keeping his mind active and vital.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Senior moments and the aging process go hand in hand. As we grow older memory lapses and cognitive problems are often assumed to be the normal course of events. But should we really worry about losing the car keys, now and then? The biological and psychological explanations for declining cognitive performance are many and varied, but Dr. Sarah Barber, an Assistant Professor in the Department of Psychology at San Francisco State University, says memory slips are not always signs of worse to come. Dr. Barber’s work at the University's Cognition and Aging Laboratory explores how emotional wellbeing and social factors affect our ability to process information. In this in-depth interview she argues that memory and attention spans in older people actually improve when they are in a positive environment; and explains why being aware of the passage of time influences how we do with memory tasks.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Ethel Travis wants to make history. At the age of 102, the former ballerina, artist and fashionista has her sights set firmly on the future. With a busy social calendar, good health and the support a loving family, Ethel embraces life with giddy enthusiasm. She loves to talk, reminisce and make new friends. A centenarian with the mind and body of someone decades younger, Ethel recently welcomed LLAMA host Peter Bowes into her home, in Newport Beach, California, for a conversation about age, attitude and humanity.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

A hundred years from now, "physicians will have the capacity to keep people alive indefinitely,” says Dr. Michael Rose, director and professor in the Department of Ecology and Evolutionary Biology at the University of California, Irvine. Dr. Rose has spent over 40 years working with fruit flies to try to unravel the mechanisms at work as we age. He believes that there is a point (which can be manipulated) in our lives, when aging ends. It is followed by a "post-aging phase of biological immortality" before we die. Dr. Rose, co-founder of Lyceum Pharmaceuticals, a research startup in California, focuses on trying to "re-tune" patterns of aging to help us live longer and better lives. In this in-depth interview, he explains his “four-steps to the conquest of aging,” and the importance of living an “age appropriate lifestyle." 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Phil Libin, co-founder and former CEO of Evernote, the note-taking app, recently moved into a new phase of his life. He turned 45, launched a new AI startup studio, All Turtles, and perhaps most significantly, lost a ton of weight. Phil has been a big guy since his late teens. He knew he was obese but did nothing about it until eight months ago. That’s when he decided to join the growing clan of fasting enthusiasts in Silicon Valley. It worked. He has lost 86 pounds (39 kilograms). Blood tests suggest he could be 20 years younger. And here’s the kicker: Phil says he plans to continue fasting indefinitely - not because he needs to lose much more weight but because he enjoys a sustained feeling of "mild euphoria" while not eating. He fasts periodically for up to eight days at a time. In this in-depth interview, Phil explains why his extreme regime is so invigorating; how he pushed back at his doctor, who thought it was a bad idea; and why he likens fasting to skydiving.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

As human life expectancy continues to increase, age-related diseases are the main impediment to enjoying the fruits of longevity. High on the list is Alzheimer’s disease, the incurable neurodegenerative condition that robs sufferers of their memory and eventually leads to death. But valuable progress is being made in the understanding and prevention of the disease. A new study at the Keck School of Medicine of USC in Los Angeles has revealed that biological changes in the brain occur long before symptoms of Alzheimer’s become apparent. The research, led by neuropsychologist Dr. Duke Han, suggests that cognitive tests are able to detect early stage of the disease in people without symptoms. In this in-depth interview, Dr Han argues that routine brain testing should be incorporated into annual physical check ups for people of all ages.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Why do women live longer than men? Does the ability to bear children play a role and to what extent do evolutionary forces discriminate between men and women? Dr. Felice Gersh is a board-certified (1984) gynecologist and the founder of a private medical practice, the Integrative Medical Group of Irvine, California. Fellowship trained in a relatively new medical field, known as functional/integrative medicine, Dr. Gersh believes longevity is connected to estrogen. She argues that it is the “most maligned and insulted” of all hormones and acts a natural anti-inflamatory agent to promote good health in both women and men. Dr. Gersh is a leading voice on women’s health issues. She advocates for a better understanding of the role stomach bacteria play in living a long, healthy life. A prolific speaker, she believes doctors should “expand their tool boxes” to include acupuncture, herbal medicine and meditation. In this in-depth interview Dr. Gersh explains why she “had to unlearn” about half of everything she learned at medical school calls for a fundamental “shake-up” in the delivery of health care.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The enhancement of the human body is the main goal of Geoffrey Woo, a biohacker and entrepreneur based in San Francisco. A Stanford-trained computer scientist, Geoffrey is the CEO and co-founder of HVMN (formerly Nootrobox), a nootropics company that melds biology and technology to optimize the human system. The evolving science behind nootropics, which are legal compounds designed to improve cognitive function, has become big business in Silicon Valley. Geoffrey sees the human body as a quantifiable and manipulable system, and the next platform for innovation and growth. Along with his employees, he is also an enthusiastic proponent of fasting, Together, they have built a vibrant community of like-minded followers, known as WeFast. They regularly deprive themselves of food, in the pursuit of good health and longevity. In this in-depth interview, Geoffrey shares his enthusiasm for biohacking and explains why he believes everyone will be fasting within the next two years.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

James Maskell is a writer, public speaker, entrepreneur and advocate for a new paradigm in healthcare. The author of The Evolution of Medicine, James is the founder of the Functional Forum, an integrative medicine conference that curates discussions with leading medical practitioners around the world. Next week, James will co-host the launch of an ambitious project to make Guernsey the first community in the world to achieve a life expectancy of 100. Named 'Journey to 100,' the goal is to radically improve the health and longevity of people living on the island through a greater emphasis on preventative medicine, purpose in life and a proactive approach to wellbeing.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Curt von Badinski is a serial tinkerer, inventor, entrepreneur and businessman. As a mechanical engineer he worked on secret projects at the aerospace company, Lockheed Martin; he developed network equipment at the IT giant, Cisco Systems, and he built a family company making camera accessories. It was during this enterprise that Curt realized his work-obsessed and sleep deprived “crazy” lifestyle was making him sick. It was a light-bulb moment that convinced Curt to use his tech expertise to focus on his health and longevity. He created Motiv, a San Francisco-based startup, with the initial goal of developing a discreet hand ring to monitor physical activity and sleep patterns. The Motiv Ring launches during the summer. Curt still lives a moderately crazy lifestyle, as LLAMA host Peter Bowes discovered, when they met in Burbank, California.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

In the months before her retirement, Sue Albert was worried that she may not survive to enjoy her golden years. She spent a lifetime in nursing, and ended her career as the dean of a health department at a California college. But Sue was burned out and sick. She had neglected her own health needs and was overweight, hypertensive and physically challenged. She decided to join a gym and, albeit reluctantly, embarked on a life-changing – possibly life-saving – workout regime. This week Sue heads to Belarus to compete in the World Powerlifting Championships. LLAMA host Peter Bowes met Sue at her gym, Results Fitness, in Newhall, California, for an inspiring conversation about her new-found youth and vitality. She reveals the secret to her physical and mental transformation - swapping her “can’t do” attitude for the mindset of a champion weightlifter. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

The biological mechanisms at work during the aging process have long since intrigued and baffled scientists. Indeed, the very definition of aging continues to be the subject of much debate. The relationship between growing old and chronic disease is pivotal to the understanding of human longevity and the focus of many clinical studies. Dr. David Gems is a professor of biogerontology at the Institute of Healthy Aging, University College London. A leading voice in the quest to unravel the mysteries of aging, he works with tiny worms, called nematodes, to try to shed some light on the process. In this in-depth interview, David reveals why his theories about aging have shifted over the years. He argues that there in no central “underlying aging process” caused by damage or the body wearing out, as scientists once thought. The reality, he says, is “more complex and nuanced”.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

People with a brain age older than their bodies could be at greater risk of dying early, according to a recent study. Dr. James Cole, a neuroscientist at Imperial College London, led a research project using MRI scans and a computer program to predict a person’s brain age. The system, which is still in development, could help spot people whose lifestyles put them at greater risk of poor health and early death. LLAMA host Peter Bowes visited Hammersmith Hospital in London for this in-depth interview with Dr. Cole, who explains how data for the study was collected and how the findings could be used to help people live longer lives. He also discusses what some people call “the mosaic of aging”, the idea that different tissues and systems in the body can age at a different pace.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Implanted devices that monitor the internal functioning of our bodies, in minute detail, could soon be part of our daily lives. Many of us already take for granted the wearable gadgets and apps we use to keep track of exercise and food intake. Technological advances in the field of body computing are moving quickly and are about to revolutionize the way we manage aging and everyday wellbeing. Dr. Leslie Saxon is a professor of clinical medicine at the Keck School of Medicine of the University of Southern California (USC). She specializes in the diagnosis and treatment of cardiac arrhythmias and the prevention of sudden cardiac death. The founder and executive director of USC’s Center for Body Computing and the newly formed USC Virtual Care Clinic, Dr. Saxon is a global authority on the development of wearable and implanted technology. In this in-depth interview, she discusses the potential for body computing to enhance our lives and longevity.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Living a healthy lifestyle goes a long way towards reducing the chances of an early death, but some diseases still strike with little warning and deadly effect. You can do everything right and still get cancer. Dr. Steven Eisenberg is an oncologist, based in the California city of San Diego. Board-certified in internal medicine, medical oncology and hematology, he has been recognized for his compassionate bedside manner. He is best known for singing to his patients. Not only does he burst into song on the ward, he writes heart-lifting and personalized lyrics for his patients. In this in-depth interview he talks about his desire to provide an empathetic environment for people as they face up to their diagnosis. Dr. Eisenberg also shares his thoughts on the roles of diet, exercise and mindfulness in cancer prevention.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Edith Johnson Avise recently moved into a care home, at the age of 100. After a lifetime of independent living, she is finding it difficult to adapt to her new surroundings. The home, in Southern California, is comfortable and safe, but Edith still has a spirited attitude towards life. She enjoyed a successful career as an agricultural educator, or extension worker, in her home state of Michigan. She traveled the country and worked closely with 4-H, the youth organization that teaches young people life skills through practical programs. In this candid interview Edith shares her life experiences and wisdom. She reveals what she considers to be the key tenets to living a long and healthy life and puts into context the value of living to a ripe old age. Edith is sharp, quick-witted, and remarkably honest. 

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Paul Irving has no intention of ever retiring. As chairman of the Milken Institute’s Center for the Future of Aging, he is a leading campaigner in what has become known as the purposeful aging movement. A lawyer and former president of the Santa Monica-based Institute, Paul is an advocate for the elderly population, whom he sees as a talented and “dramatically underutilized” resource for society. Author of The Upside of Aging: How Long Life Is Changing the World of Health, Work, Innovation, Policy and Purpose, he says longevity is creating an entirely new definition of what it is like to be old. From going back to school in your sixties to romances springing up late in life, Paul views aging with relish and optimism. In this in-depth interview, he explains why he considers aging, along with climate change, to be the “great challenge of the 21st century”. He also discusses the Institute’s upcoming global conference, ‘Building Meaningful Lives,’ taking place in Los Angeles from April 30-May 3, 2017.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Imagine a future where we grow old but do not succumb to the diseases that typically define the aging process. Dr. Nathaniel “Ned” David, a molecular and cell biologist, wants to create a world where it does not hurt to grow old. The founder of multiple biotech companies, Ned is the President of UNITY, a San Francisco-based biotechnology company which aims to develop drugs that prevent, halt, or reverse age-related diseases. Named one of the Top 100 innovators in the world under 35, by the MIT Technology Review, Ned combines personal experience with a passion for changing the definition of old age. In this in-depth interview, he discusses his goal of producing a drug to target senescent cells that are linked to some of the diseases of old age. Ned also talks about his personal quest to avoid age-related cognitive decline and to overcome a debilitating condition, degenerative disc disease, which means he is no longer able to run.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

When Matthew Hoffman decided to interview elderly people, to hone his skills as a TV host, he stumbled across a unique community project. Matthew, a writer and actor, is the founder of Tuesdays with Matthew, an acting class and video series for senior citizens in Los Angeles. The program, at an adult day care center, takes iconic scenes from famous movies and reenacts them with senior citizens in the lead roles. At a time when many elderly people say they enjoy good health, but often feel socially isolated and lonely, the class is a fun and novel way to inject new purpose into their lives. It may just help them to live longer. Dr. Caroline Cicero teaches social policy and aging at the University of Southern California, Davis School of Gerontology. She focusses on the intersection of aging, urban planning and the delivery of services to make local communities better places to grow old. For this episode of LLAMA, Dr. Cicero reviews Tuesdays with Matthew. She explains why it could promote longevity by focussing on aspects of life such as socialization, participation and inclusion. LLAMA host Peter Bowes spoke to Dr Cicero in Los Angeles and visited Tuesdays with Matthew to meet some remarkable, age-defying, seniors.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Ben Hwang is the chairman and CEO of Profusa, a San Francisco-based biotechnology company, that is developing micro sensors to monitor body chemistry. A former management consultant, Ben earned his MA and PhD in biology from the Johns Hopkins University. He has worked in a variety of biotech roles and is dedicated to developing technology that promotes good health and longevity. Profusa (@profusaInc) is on a mission is to make the inner workings of our bodies more accessible. The goal, using micro sensors, is to gather information about internal biochemical changes, in real time. The 3 to 5 mm long sensors are designed to be compatible with the body’s tissues for long-term monitoring. They collect data, transmitted to external devices, providing a stream of information for long-term health and wellness. Ben Hwang spoke to LLAMA host, Peter Bowes, at TEDMED in California.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Eric Verdin is the president and chief executive officer of the Buck Institute for Research on Aging. The institute, based in Novato, Northern California, is America's first and largest independent body focussed on the biology of aging. Until recently, Dr. Verdin was a senior investigator at the Gladstone Institutes, in San Francisco, where he studied the role of metabolism and diet in aging. A world-renowned expert in the field, Dr. Verdin is trying to better understand the mechanisms linking caloric restriction to increased health span and longevity.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

How is human longevity influenced by our mindsets on aging, diet, exercise and stress? Inspired by research on the placebo effect, Alia Crum (@AliaCrum), an assistant professor of psychology at Stanford University, investigates the role mindset plays in health and lifestyle choices. She is trying understand how mindsets can have a positive impact on the way the body heals and whether they can be influenced to bring about physical and psychological well-being.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Nir Barzilai is a professor of medicine and genetics at the Albert Einstein College of Medicine and the director of the Institute for Aging Research. He is best known for his work with some of the world’s oldest populations and is currently leading an international effort to aprove drugs that could target aging. Dr. Barzilai was born in Isreal and has had a life-long interest in the mechanisms that control the aging process. He hypothesizes that centenarians have protective genes which delay aging or protect against age-related diseases. 

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)

Dr. Aseem Malhotra is a campaigner against the excessive consumption of sugar. A National Health Service (NHS) doctor and consultant cardiologist in the UK, he believes that too much sugar in our diets can lead to medical conditions commonly associated with aging – including obesity, type 2 diabetes, and heart disease. A global health advocate and avowed foodie, Aseem is also a writer, and recently completed ‘The Big Fat Fix’ – a film which highlights what he sees as the myths behind our understanding of sugar, fat, and exercise.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Olga Connolly is an Olympic gold medalist, who triumphed during the 1956 games in Melbourne. She threw the discus for her home country, Czechoslovakia. During the competition, she fell in love with, and later married, American athlete Harold Connolly – a controversial move at the height of the Cold War. Now 84, Olga has forged a career in fitness, working as a personal trainer at the University of California, Irvine, specializing in holistic fitness studies and training.

Affiliation disclosure: This site includes affiliate links from which we derive a small commission, if you click on the product links and use the code LLAMA at checkout.  This helps support the channel and allows us to continue sharing conversations like this. LLAMA is available, free of charge, wherever you get your podcasts. Our mission is to explore the science and lifestyle interventions that could help us live longer and better. Thank you for the support!

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Valter Longo is Director of the University of Southern California (USC) Longevity Institute and a professor in biological science. Originally from Italy, he is a cell biologist who specializes in the mechanisms of aging in yeast, mice, and humans. His laboratory has identified genetic pathways that regulate aging in simple organisms and reduce the incidence of certain diseases in mice and humans. Valter has also developed a dietary regime – known as the fasting mimicking diet – that may reduce risk factors for aging in people.

Affiliation disclosure: DoNotAge.org is offering listeners to LLAMA a 10% discount on its range of products, including NAD boosters. The podcast receives a small commission when you use the use code LLAMA for purchases at DoNotAge.org - it helps to cover production costs and ensures that our interviews remain free for all to listen. Health queries can be answered by emailing: hello@donotage.org

Peter Bowes, a journalist and Los Angeles-based broadcaster, presents the launch episode of the Live Long and Master Aging (LLAMA) podcast, exploring the science and stories behind human longevity. In each episode we interview leading longevity scientists and remarkable people who have mastered the art of aging.

DoNotAge.org is on a mission to extend healthspan for as many people as possible.  The longevity research organisation is offering listeners to LLAMA a 10% discount on its range of products - NAD boosters, Sirtuin activators, senolytics & more.  Use the code LLAMA at checkout. This is a great way for you to support the podcast. Any health queries can be answered by the team at DoNotAge: email - hello@donotage.org

Support the show (https://www.paypal.com/donate/?hosted_button_id=B6J44X8APFEJA)