The Peter Attia Drive

By Peter Attia, MD

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Category: Medicine

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Subscribers: 6263
Reviews: 8
Episodes: 372


 Apr 20, 2022


 Apr 20, 2022

Rob
 Mar 29, 2020

Joe M
 Jul 20, 2019
Has risen through the ranks to become my favorite podcast, I get excited when I see a new episode come out. Such a thoughtful and thought filled podcast I always learn something new even if a lot of the medical ones are a bit over my head.


 Jul 10, 2019

Description

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

Episode Date
#325 ‒ Peter’s key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3
Nov 11, 2024
#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.
Nov 04, 2024
#323 - CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D.
Oct 28, 2024
#322 - Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D.
Oct 21, 2024
#321 – Dopamine and addiction: navigating pleasure, pain, and the path to recovery | Anna Lembke, M.D.
Oct 14, 2024
#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) - efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape
Oct 07, 2024
#319 ‒ Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2
Sep 30, 2024
#318 ‒ Cycling phenom and Tour de France champion Tadej Pogačar reveals his training strategies, on-bike nutrition, and future aspirations
Sep 23, 2024
#317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.
Sep 16, 2024
#316 - AMA #63: A guide for hair loss: causes, treatments, transplants, and sex-specific considerations
Sep 09, 2024
Improve your decision-making, frameworks for learning, backcasting, and more | Annie Duke (#60 rebroadcast)
Sep 02, 2024
#315 ‒ Life after near-death: a new perspective on living, dying, and the afterlife | Sebastian Junger
Aug 26, 2024
#314 ‒ Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D.
Aug 19, 2024
#313 - AMA #62: Protein’s impact on appetite and weight management, and uric acid's link to disease and how to manage levels
Aug 12, 2024
#312 - A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D.
Aug 05, 2024
#311 ‒ Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more
Jul 29, 2024
#310 - The relationship between testosterone and prostate cancer, testosterone replacement therapy, and tools for predicting cancer aggressiveness and guiding therapy | Ted Schaeffer, M.D., Ph.D.
Jul 22, 2024
#309 ‒ AI in medicine: its potential to revolutionize disease prediction, diagnosis, and outcomes, causes for concern in medicine and beyond, and more | Isaac Kohane, M.D., Ph.D.
Jul 15, 2024
Zone 2 training: impact on longevity and mitochondrial function, how to dose frequency and duration, and more | Iñigo San-Millán, Ph.D. (#201 rebroadcast)
Jul 08, 2024
#308 - AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more
Jul 01, 2024
#307 ‒ Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D.
Jun 24, 2024
#306 - AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more
Jun 17, 2024
#305 ‒ Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson
Jun 10, 2024
#304 – NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more
Jun 03, 2024
#303 - A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease | Dena Dubal, M.D., Ph.D.
May 27, 2024
#302 - Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage liver disease | Julia Wattacheril, M.D., M.P.H.
May 20, 2024
#301 - AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it
May 13, 2024
#300 - Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?
May 06, 2024
Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death
Apr 29, 2024
#299 ‒ Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.
Apr 22, 2024
#298 ‒ The impact of emotional health on longevity, self-audit strategies, improving well-being, and more | Paul Conti, M.D.
Apr 15, 2024
#297 - AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency
Apr 08, 2024
#296 ‒ Foot health: preventing and treating common injuries, enhancing strength and mobility, picking footwear, and more | Courtney Conley, D.C.
Apr 01, 2024
#295 ‒ Roadway death and injury: why everyone should care and what you can do to reduce risk | Mark Rosekind, Ph.D.
Mar 25, 2024
#294 ‒ Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu
Mar 18, 2024
#293 - AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity
Mar 11, 2024
#292 ‒ Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCK | Jason McCarthy
Mar 04, 2024
#291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more | Derek, More Plates More Dates Pt.2
Feb 26, 2024
#290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D.
Feb 19, 2024
#289 - AMA #56: Cancer screening: pros and cons, screening options, interpreting results, and more
Feb 12, 2024
#288 ‒ The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green
Feb 05, 2024
#287 ‒ Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D.
Jan 29, 2024
#286 ‒ Journal club with Andrew Huberman: the impact of light exposure on mental health and an immunotherapy breakthrough for cancer treatment
Jan 22, 2024
#285 - AMA #55: Exercise: longevity-focused training, goal setting, improving deficiencies, managing emotional stress, and more
Jan 15, 2024
#284 ‒ Overcoming addictive behaviors, elevating wellbeing, thriving in an era of excess, and the scarcity loop | Michael Easter, M.A.
Jan 08, 2024
James Clear: Building & Changing Habits (#183 rebroadcast)
Jan 01, 2024
#283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D.
Dec 18, 2023
#282 - AMA #54: Magnesium: risks of deficiency, how to correct it, supplement options, potential cognitive and sleep benefits, and more
Dec 11, 2023
#281 ‒ Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) | Rich Miller, M.D., Ph.D.
Dec 04, 2023
#280 ‒ Cultivating happiness, emotional self-management, and more | Arthur Brooks Ph.D.
Nov 27, 2023
The world’s most important doctor to millions in the war-torn and remote villages of Sudan | Tom Catena, M.D. (#40 rebroadcast)
Nov 20, 2023
#279 - AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins
Nov 13, 2023
#278 ‒ Breast cancer: how to catch, treat, and survive breast cancer | Harold Burstein, M.D., Ph.D.
Nov 06, 2023
#277 ‒ Food allergies: causes, prevention, and treatment with immunotherapy | Kari Nadeau, M.D., Ph.D.
Oct 30, 2023
#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more
Oct 23, 2023
#275 - AMA #52: Hormone replacement therapy: practical applications and the role of compounding pharmacies
Oct 16, 2023
#274 - Performance-enhancing drugs and hormones: risks, rewards, and broader implications for the public | Derek: More Plates, More Dates
Oct 09, 2023
#273 ‒ Prostate health: common problems, cancer prevention, screening, treatment, and more | Ted Schaeffer, M.D., Ph.D.
Oct 02, 2023
#272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D.
Sep 25, 2023
#271 - AMA #51: Understanding and improving your metabolic health
Sep 18, 2023
#270 ‒ Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers
Sep 11, 2023
#269 - Good vs. bad science: how to read and understand scientific studies
Sep 04, 2023
#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.
Aug 28, 2023
#267 ‒ The latest in cancer therapeutics, diagnostics, and early detection | Keith Flaherty, M.D.
Aug 21, 2023
#266 - AMA #50: Genetics: how they impact disease risk, what you can do about it, testing, and more
Aug 14, 2023
#265 - Time, productivity, and purpose: insights from Four Thousand Weeks | Oliver Burkeman
Aug 07, 2023
#264 ‒ Hip, knee, ankle, and foot: common injuries, prevention, and treatment options
Jul 31, 2023
#263 ‒ Concussions and head trauma: symptoms, treatment, and recovery | Micky Collins, Ph.D.
Jul 24, 2023
#262 - AMA #49: Heart rate recovery, strength training, rucking, kidney function, and brain health
Jul 17, 2023
#261 ‒ Training for The Centenarian Decathlon: zone 2, VO2 max, stability, and strength | Peter Attia, M.D.
Jul 10, 2023
Cancer screening with full-body MRI scans and a seminar on the field of radiology | Rajpaul Attariwala, M.D., Ph.D. (#61 rebroadcast)
Jul 03, 2023
#260 ‒ Men’s Sexual Health: why it matters, what can go wrong, and how to fix it | Mohit Khera, M.D., M.B.A., M.P.H.
Jun 26, 2023
#259 - Women's sexual health: Why it matters, what can go wrong, and how to fix it | Sharon Parish, M.D.
Jun 19, 2023
#258 - AMA #48: Blood pressure—how to measure, manage, and treat high blood pressure
Jun 12, 2023
#257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Tommy Wood, M.D., Ph.D.
Jun 05, 2023
#256 ‒ The endocrine system: exploring thyroid, adrenal, and sex hormones | Peter Attia, M.D.
May 29, 2023
#255 ‒ Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease and CVD, familial hypercholesterolemia, and more | John Kastelein, M.D., Ph.D.
May 22, 2023
#254 - AMA #47: Cold therapy: pros, cons, and its impact on longevity
May 15, 2023
#253 ‒ Hormone replacement therapy and the Women’s Health Initiative: re-examining the results, the link to breast cancer, and weighing the risk vs reward of HRT | JoAnn Manson, M.D.
May 08, 2023
#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D.
May 01, 2023
The impact of stress on our physical and emotional health | Robert Sapolsky, Ph.D. (#51 rebroadcast)
Apr 24, 2023
#251 - AMA #46: Optimizing brain health: Alzheimer's disease risk factors, APOE, prevention strategies, and more
Apr 17, 2023
#250 ‒ Training principles for longevity | Andy Galpin, Ph.D. (PART II)
Apr 10, 2023
#249 ‒ How the brain works, Andrew’s fascinating backstory, improving scientific literacy, and more | Andrew Huberman, Ph.D.
Apr 03, 2023
#248 ‒ OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation, main themes, and more
Mar 28, 2023
#247 ‒ Preventing cardiovascular disease: the latest in diagnostic imaging, blood pressure, metabolic health, and more | Ethan Weiss, M.D.
Mar 20, 2023
#246 - AMA #45:  Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent
Mar 13, 2023
#245 ‒ Overcoming trauma, finding inner peace, and living a meaningful and fulfilling life | Lewis Howes
Mar 06, 2023
#244 ‒ The history of the cell, cell therapy, gene therapy, and more | Siddhartha Mukherjee
Feb 27, 2023
#243 ‒ The fentanyl crisis and why everyone should be paying attention | Anthony Hipolito
Feb 20, 2023
#242 - AMA #44: Peter’s historical changes in body composition with his evolving dietary, fasting, and training protocols
Feb 13, 2023
#241 ‒ Living intentionally, valuing time, prioritizing relationships, and more keys to a rich life | Ric Elias (Part 2)
Feb 06, 2023
#240 ‒ The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D.
Jan 30, 2023
#239 ‒ The science of strength, muscle, and training for longevity | Andy Galpin, Ph.D. (PART I)
Jan 23, 2023
#238 – AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease
Jan 16, 2023
#237 ‒ Optimizing life for maximum fulfillment | Bill Perkins
Jan 09, 2023
#236 ‒ Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D.
Jan 02, 2023
James Clear: Building & Changing Habits (#183 rebroadcast)
Dec 26, 2022
#235 ‒ Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more | Layne Norton, Ph.D.
Dec 19, 2022
#234 ‒ Chris Hemsworth on Limitless, longevity, and happiness
Dec 12, 2022
#233 - AMA #42: Optimizing sleep - bedtime routine, molecule regimen, sleep trackers, sauna, & more
Dec 05, 2022
#232 ‒ Shoulder, elbow, wrist, and hand: diagnosis, treatment, and surgery of the upper extremities | Alton Barron, M.D.
Nov 28, 2022
A masterclass on insulin resistance—mechanisms and implications | Gerald Shulman, M.D., Ph.D. (#140 rebroadcast)
Nov 21, 2022
#231 - AMA #41: Medicine 3.0, developments in the field of aging, healthy habits in times of stress, and more
Nov 14, 2022
#230 ‒ Cardiovascular disease in women: prevention, risk factors, lipids, and more | Erin Michos, M.D.
Nov 07, 2022
#229 ‒ Understanding cardiovascular disease risk, cholesterol, and apoB
Oct 31, 2022
#228 ‒ Improving body composition, female-specific training principles, and overcoming an eating disorder | Holly Baxter, APD
Oct 24, 2022
#227 - AMA #40: Body composition, protein, time-restricted feeding, fasting, DEXA scans, and more
Oct 17, 2022
#226 ‒ The science of happiness | Arthur Brooks, Ph.D.
Oct 10, 2022
#225 ‒ The comfort crisis, doing hard things, rucking, and more | Michael Easter, MA
Oct 03, 2022
#224 ‒ Dietary protein: amount needed, ideal timing, quality, and more | Don Layman, Ph.D.
Sep 26, 2022
#223 - AMA #39: The Centenarian Decathlon, zone 2, VO2 max, and more
Sep 19, 2022
#222 ‒ How nutrition impacts longevity | Matt Kaeberlein, Ph.D
Sep 12, 2022
#221 ‒ Understanding sleep and how to improve it
Sep 05, 2022
#220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.
Aug 29, 2022
#219 ‒ Dialectical behavior therapy (DBT): skills for overcoming depression , emotional dysregulation, and more | Shireen Rizvi, Ph.D., ABPP
Aug 22, 2022
#218 - AMA #38: Can you exercise too much?
Aug 15, 2022
#217 ‒ Exercise, VO2 max, and longevity | Mike Joyner, M.D.
Aug 08, 2022
#216 - Metabolomics, NAD+, and cancer metabolism | Josh Rabinowitz, M.D., Ph.D.
Aug 01, 2022
#215 - The gut-brain connection | Michael Gershon, M.D.
Jul 25, 2022
#214 - AMA #37: Bone health—everything you need to know
Jul 18, 2022
#213 ‒ Liquid biopsies and cancer detection | Max Diehn, M.D. Ph.D.
Jul 11, 2022
Earning the gift of life | Ric Elias (#79 rebroadcast)
Jul 04, 2022
#212 - The neuroscience of obesity | Stephan Guyenet, Ph.D.
Jun 27, 2022
#211 - AMA #36: Fruits & vegetables—everything you need to know
Jun 20, 2022
#210 - Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D.
Jun 13, 2022
#209 ‒ Medical mistakes, patient safety, and the RaDonda Vaught case | Marty Makary, M.D., M.P.H.
Jun 06, 2022
The Art of Stability | Beth Lewis (Ep. #131 Rebroadcast)
May 30, 2022
#208 - Tragedy, grief, healing, and finding happiness | Kelsey Chittick
May 23, 2022
#207 - AMA #35: "Anti-Aging" Drugs — NAD+, metformin, & rapamycin
May 16, 2022
#206 - Exercising for longevity: strength, stability, zone 2, zone 5, and more
May 09, 2022
#205 - Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2)
May 02, 2022
#204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.
Apr 25, 2022
#203 - AMA #34: What Causes Heart Disease?
Apr 18, 2022
#202 - Peter on nutrition, disease prevention, sleep, and more — looking back on the last 100 episodes
Apr 11, 2022
In remembrance of Sarah Hallberg, D.O., M.S. (Ep. #162 Rebroadcast)
Apr 04, 2022
#201 - Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)
Mar 28, 2022
#200 - AMA #33: Hydration—electrolytes, supplements, sports drinks, performance effects, and more
Mar 21, 2022
#199 - Running, overcoming challenges, and finding success | Ryan Hall
Mar 14, 2022
#198 - Eye health—everything you need to know | Steven Dell, M.D.
Mar 07, 2022
#197 - The science of obesity & how to improve nutritional epidemiology | David Allison, Ph.D.
Feb 28, 2022
#196 - AMA #32: Exercise, squats, deadlifts, BFR, and TRT
Feb 21, 2022
#195 - Freedom, PTSD, war, and life through an evolutionary lens | Sebastian Junger
Feb 14, 2022
#194 - How fructose drives metabolic disease | Rick Johnson, M.D.
Feb 07, 2022
#193 - AMA #31: Heart rate variability (HRV), alcohol, sleep, and more
Jan 31, 2022
#192 - COVID Part 2: Masks, long COVID, boosters, mandates, treatments, and more
Jan 24, 2022
#191 - Revolutionizing our understanding of mental illness with optogenetics | Karl Deisseroth M.D., Ph.D.
Jan 17, 2022
#190 - Paul Conti, M.D.: How to heal from trauma and break the cycle of shame
Jan 10, 2022
#189 - COVID-19: Current state of affairs, Omicron, and a search for the end game
Jan 03, 2022
Iñigo San Millán, Ph.D.: Zone 2 Training and Metabolic Health (Ep. #85 Rebroadcast)
Dec 27, 2021
#188 - AMA #30: How to Read and Understand Scientific Studies
Dec 20, 2021
#187 - Sam Apple: The Warburg Effect—Otto Warburg’s cancer metabolism theory
Dec 13, 2021
#186 - Patrick Radden Keefe: The opioid crisis—origin, guilty parties, and the difficult path forward
Dec 06, 2021
#185 - Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we assess risk
Nov 29, 2021
Rick Johnson, M.D.: Metabolic Effects of Fructose (Ep. #87 Rebroadcast)
Nov 22, 2021
#184 - AMA #29: GLP-1 Agonists—The Future of Treating Obesity?
Nov 15, 2021
#183 - James Clear: Building & changing habits
Nov 08, 2021
#182 - David Nutt: Psychedelics & Recreational Drugs
Nov 01, 2021
#181 - Robert Gatenby, M.D.: Viewing cancer through an evolutionary lens and why this offers a radically different approach to treatment
Oct 25, 2021
#180 - AMA #28: All things testosterone and testosterone replacement therapy
Oct 18, 2021
#179 - Jeremy Loenneke, Ph.D.: The science of blood flow restriction—benefits, uses, and what it teaches us about the relationship between muscle size and strength
Oct 11, 2021
#178 - Lance Armstrong: The rise, fall, and growth of a cycling legend
Oct 04, 2021
#177 - Steven Rosenberg, M.D., Ph.D.: The development of cancer immunotherapy and its promise for treating advanced cancers
Sep 27, 2021
#176 - AMA #27: The importance of muscle mass, strength, and cardiorespiratory fitness for longevity
Sep 20, 2021
#175 - Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process
Sep 13, 2021
#174 - Lawrence Wright: The 20th anniversary of the 9/11 attacks: reflections on how they happened, and lessons learned and not learned
Sep 06, 2021
#173 - AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions
Aug 23, 2021
#172 - Esther Perel: The effects of trauma, the role of narratives in shaping our worldview, and why we need to accept uncomfortable emotions
Aug 16, 2021
#171 - Steve Austad, Ph.D.: The landscape of longevity science: making sense of caloric restriction, biomarkers of aging, and possible geroprotective molecules
Aug 09, 2021
#170 - AMA #25: Navigating the complexities and nuances of cancer screening
Jul 26, 2021
#169 - Katherine Eban: COVID-19 Lab Leak: Examining all sides of the debate and discussing barriers to a full investigation
Jul 19, 2021
#168 - Hugh Jackman: Reflections on acting, identity, personal transformation, and the significance of being Wolverine
Jul 12, 2021
#167 - Gary Taubes: Bad science and challenging the conventional wisdom of obesity
Jun 28, 2021
#166 - Patricia Corby, D.D.S.: Importance of oral health, best hygiene practices, and the relationship between poor oral health and systemic disease
Jun 21, 2021
#165 - AMA #24: Deep dive into blood glucose: why it matters, important metrics to track, and superior insights from a CGM
Jun 14, 2021
#164 - Amanda Smith, M.D.: Diagnosing, preventing, and treating Alzheimer’s disease, and what we can all learn from patients with dementia
Jun 07, 2021
#163 - Layne Norton, Ph.D.: Building muscle, losing fat, and the importance of resistance training
May 24, 2021
#162 - Sarah Hallberg, D.O., M.S.: Challenging the status quo of treating metabolic disease, and a personal journey through a grim cancer diagnosis
May 17, 2021
#161 - AMA #23: All Things Nicotine: deep dive into its cognitive and physical benefits, risks, and mechanisms of action
May 10, 2021
#160 - Paul Offit, M.D.: The latest on COVID-19 vaccines and their safety, herd immunity, and viral variants
May 03, 2021
#159 - Peter Hotez, M.D., Ph.D.: Evolution of the anti-vaccine movement, the causes of autism, and COVID-19 vaccine state of affairs
Apr 26, 2021
#158 - Brian Deer: A tale of scientific fraud—exposing Andrew Wakefield and the origin of the belief that vaccines cause autism
Apr 19, 2021
#157 - AMA #22: Losing fat and gaining fat: the lessons of fat flux
Apr 12, 2021
#156 - Jake Muise: Humanely harvesting axis deer while alleviating its impact on Hawaii’s vulnerable ecosystems
Apr 05, 2021
#155 - Chris Sonnenday, M.D.: The history, challenges, and gift of organ transplantation
Mar 29, 2021
#154 - Steve Levitt, Ph.D.: A rogue economist’s view on climate change, mental health, the ethics of experiments, and more
Mar 22, 2021
#153 - AMA #21: Deep dive into olive oil, high-intensity exercise, book update, and more
Mar 15, 2021
#152 - Michael Rintala, D.C.: Principles of Dynamic Neuromuscular Stabilization (DNS)
Mar 08, 2021
#151 - Alex Hutchinson, Ph.D.: Translating the science of endurance and extreme human performance
Mar 01, 2021
#150 - Senator Bill Frist, M.D.: A modern Renaissance man's journey through science, politics, and business
Feb 22, 2021
#149 - AMA #20: Simplifying the complexities of insulin resistance: how it's measured, how it manifests in the muscle and liver, and what we can do about it
Feb 15, 2021
#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program
Feb 08, 2021
#147 - Hussein Yassine, M.D.: Deep dive into the “Alzheimer’s gene” (APOE), brain health, and omega-3s
Feb 01, 2021
#146 - Guy Winch, Ph.D.: Emotional first aid and how to treat psychological injuries
Jan 25, 2021
#145 - AMA #19: Deep dive on Zone 2 training, magnesium supplementation, and how to engage with your doctor
Jan 18, 2021
#144 - Phil Maffetone: Optimizing health and performance through maximal aerobic function
Jan 11, 2021
#143 - John Ioannidis, M.D., D.Sc.: Why most biomedical research is flawed, and how to improve it
Jan 04, 2021
#142 - Robert Abbott: The Bobby Knight story—a cautionary tale of unchecked anger, ego, and winning at all costs
Dec 21, 2020
#141 - AMA #18: Deep dive: sugar and sugar substitutes
Dec 14, 2020
#140 - Gerald Shulman, M.D., Ph.D.: A masterclass on insulin resistance—molecular mechanisms and clinical implications
Dec 07, 2020
#139 - Kristin Neff, Ph.D.: The power of self-compassion
Nov 30, 2020
#138 - Lauren Miller Rogen and Richard Isaacson, M.D.: Alzheimer’s disease prevention—patient and doctor perspectives
Nov 23, 2020
#137 - Paul Offit, M.D.: An expert perspective on COVID-19 vaccines
Nov 16, 2020
#136 - AMA #17: Body composition methods tour de force, insulin resistance, and Topo Chico
Nov 09, 2020
#135 - BJ Miller, M.D.: How understanding death leads to a better life
Nov 02, 2020
#134 - James O’Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise.
Oct 26, 2020
#133 - Vinay Prasad, M.D., M.P.H: Hallmarks of successful cancer policy
Oct 19, 2020
#132 - AMA #16: Exploring hot and cold therapy
Oct 12, 2020
#131 - Beth Lewis: The Art of Stability: Learning about pain, mitigating injury, and moving better through life
Oct 05, 2020
#130 - Carol Tavris, Ph.D. & Elliot Aronson, Ph.D.: Recognizing and overcoming cognitive dissonance
Sep 28, 2020
#129 - Tom Dayspring, M.D.: The latest insights into cardiovascular disease and lipidology
Sep 21, 2020
#128 – Irene Davis, Ph.D.: The evolution of the foot, running injuries, and minimalist shoes
Sep 14, 2020
#127 - AMA #3 with sleep expert, Matthew Walker, Ph.D.: Fasting, gut health, blue light, caffeine, REM sleep, and more
Sep 07, 2020
#126 – Matthew Walker, Ph.D.: Sleep and immune function, chronotypes, hygiene tips, and addressing questions about his book
Aug 31, 2020
#125 - John Arnold: The most prolific philanthropist you may not have heard of
Aug 24, 2020
#124 - AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more
Aug 17, 2020
#123 - Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and metformin—longevity, immune enhancement, and COVID-19
Aug 10, 2020
#122 - Lori Gottlieb: Understanding pain, therapeutic breakthroughs, and keys to enduring emotional health
Aug 03, 2020
#121 - Azra Raza, M.D.: Why we're losing the war on cancer
Jul 27, 2020
#120 - AMA with Dom D’Agostino, Ph.D., Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health
Jul 20, 2020
#119 - Terry Real: Breaking the cycle of shame, anger, and depression
Jul 13, 2020
#118 - Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging
Jul 06, 2020
#117 - Stanley Perlman, M.D., Ph.D.: Insights from a coronavirus expert on COVID-19
Jun 29, 2020
#116 - AMA with Dom D’Agostino, Ph.D., Part I of II: Ketogenic diet, exogenous ketones, and exercise
Jun 22, 2020
#115 - David Watkins, Ph.D.: A masterclass in immunology, monoclonal antibodies, and vaccine strategies for COVID-19
Jun 15, 2020
#114 - Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies
Jun 08, 2020
#113: Normative errors—a conversation with my daughter about current events
Jun 03, 2020
#112 - Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it
Jun 01, 2020
#111 - AMA #14: What lab tests can (and cannot) inform us about our overall objective of longevity
May 18, 2020
#110 - Lew Cantley, Ph.D.: Cancer metabolism, cancer therapies, and the discovery of PI3K
May 11, 2020
#109 - John Dudley: The beauty in archery, the love of practice, and a model system for life
May 04, 2020
#108 - AMA #13: 3-day fasting, exogenous ketones, autophagy, and exercise for longevity
Apr 21, 2020
#107 - John Barry: 1918 Spanish flu pandemic—historical account, parallels to today, and lessons
Apr 17, 2020
#106 - Amesh Adalja, M.D.: Comparing COVID-19 to past pandemics, preparing for the future, and reasons for optimism
Apr 13, 2020
#105 - Paul Conti, M.D.: The psychological toll of a pandemic, and the societal problems it has highlighted
Apr 10, 2020
#104 - COVID-19 for kids with Olivia Attia
Apr 08, 2020
#103 - Looking back on the first 99 episodes: Strong Convictions, Loosely Held
Apr 06, 2020
#102 - Michael Osterholm, Ph.D.: COVID-19—Lessons learned, challenges ahead, and reasons for optimism and concern
Mar 31, 2020
#101 - Ryan Holiday: Finding stillness amidst chaos
Mar 27, 2020
#100 - Sam Harris, Ph.D.: COVID-19—Comprehending the crisis and managing our emotions
Mar 24, 2020
#99 - Peter Hotez, M.D., Ph.D.: Continuing the conversation on COVID-19
Mar 20, 2020
Qualy #129 - Evolutionary reasons to sleep
Mar 17, 2020
#97 - Peter Hotez, M.D., Ph.D.: COVID-19: transmissibility, vaccines, risk reduction, and treatment
Mar 14, 2020
Qualy #125 - Hierarchies in healthcare, physician burnout, and a broken system
Mar 10, 2020
#96 - David Epstein: How a range of experience leads to better performance in a highly specialized world
Mar 09, 2020
Qualy #121 - The “art” of longevity: the challenge of preventative medicine and understanding risk
Mar 03, 2020
#95 - Luke Bennett, M.D.: The emotional, cognitive, and physical demands that make Formula 1 a unique and special sport
Mar 02, 2020
Qualy #120 - What is the difference between ketone salts and esters?
Feb 28, 2020
#94 - Mark Hyman, M.D.: The impact of the food system on our health and the environment
Feb 24, 2020
Qualy #116 - Dealing with anger in spots where you know it’s coming
Feb 21, 2020
#93 - AMA with Jason Fried: Work-life balance, avoiding burnout, defining success, company culture, and more
Feb 17, 2020
Qualy #109 - How does one select the right physician as a patient?
Feb 11, 2020
92 - AMA #12: Strategies for longevity (which don't require a doctor)
Feb 10, 2020
Qualy #106 - Does LDL cause heart disease?
Feb 05, 2020
#91 – Eric Topol, M.D.: Can AI empower physicians and revolutionize patient care?
Feb 03, 2020
Qualy #102 - Is the food industry still saying that all calories contribute equally to adiposity and insulin resistance?
Jan 29, 2020
#90 - Ryan Holiday: Stillness, stoicism, and suffering less
Jan 27, 2020
Qualy #99 - The steroid controversy: Mark’s use of them and Peter’s perspective
Jan 23, 2020
#89 - AMA #11: All things fasting
Jan 20, 2020
Qualy #94 - Comparing the two broad types of meditation, and Peter’s favorite meditation apps
Jan 15, 2020
Qualy #89 - Cortisol and healthy aging
Jan 07, 2020
#87 - Rick Johnson, M.D.: Fructose—The common link in high blood pressure, insulin resistance, T2D, & obesity?
Jan 06, 2020
Qualy #85 - The past, present, and future of medicine, hospitals, and healthcare
Dec 31, 2019
#86 - Damon Hill: Overcoming loss, achieving success, and finding one's identity
Dec 30, 2019
Qualy #82 - What is the most common first presentation of heart disease?
Dec 25, 2019
#85 - Iñigo San Millán, Ph.D.: Mitochondria, exercise, and metabolic health
Dec 23, 2019
Qualy #80 - The four pillars of charity: water that helped it overcome the stigma of nonprofits and become successful
Dec 20, 2019
#84 - AMA #10: Low testosterone, hypothyroidism, building muscle (and preserving it while fasting)
Dec 16, 2019
Qualy #73 - How can we change the food system when 10 companies control almost 90 percent of the calories we consume in the US?
Dec 10, 2019
#83 - Bill Harris, Ph.D.: Omega-3 fatty acids
Dec 09, 2019
Qualy #69 - Advice to parents and kids for creating a sustainable environment that’s going to prevent them from running into metabolic problems
Dec 03, 2019
#82 - Mark Messier: Leadership, personal growth, and performing under pressure
Dec 02, 2019
Qualy #65 - The three laws of medicine — Law #1: A strong intuition is much more powerful than a weak test
Nov 26, 2019
#81 - Debra Kimless, M.D. & Steve Goldner, J.D.: Cannabis – the latest science on CBD & THC
Nov 25, 2019
Qualy #61 - Rapamycin in cancer treatment
Nov 19, 2019
#80 - Celebrity AMA #1: Fasting, rapamycin, performance vs. longevity, and more
Nov 18, 2019
Qualy #57 - A primer on NAD+/NADH, its effect on lifespan/healthspan, and a review of the supplements
Nov 12, 2019
#79 - Ric Elias: Earning the gift of life
Nov 11, 2019
Qualy #53 - Screening for prostate cancer
Nov 05, 2019
#78 - Sasha Cohen: The price of achievement, and redefining success
Nov 04, 2019
Qualy #52 - Insights about berberine
Nov 01, 2019
#77 – AMA #2 with sleep expert, Matthew Walker, Ph.D.: short sleep mutants, optimal sleep environment, sleep apnea, & rapid fire questions
Oct 28, 2019
Qualy #46 - Rapamycin’s effects on cancer, cardiovascular disease, and neurodegeneration
Oct 23, 2019
#76 - Kyle Kingsbury: Finding meaning, depression, and psychedelics
Oct 21, 2019
Qualy #43 - What are Peter’s thoughts on fasting and ketosis for females?
Oct 17, 2019
#75 - David Light: Zantac recall due to cancer concerns – what you need to know
Oct 14, 2019
Qualy #38 - Finding meaning in struggle and why we are less happy than ever (David Foster Wallace)
Oct 09, 2019
#74 – Jason Fried: Optimizing efficiency and work-life balance
Oct 07, 2019
Qualy #33 - How silent bravado and incessant striving can lead to a functional (and actual) death, and why Paul is critical of the current state of psychiatry
Oct 01, 2019
#73 - AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more
Sep 30, 2019
#72 - Dan Harris: 10% happier – meditation, kindness, and compassion
Sep 23, 2019
Qualy #26 - What is Peter looking to achieve and monitor with his blood glucose monitor?
Sep 18, 2019
#71 - Katherine Eban: Widespread fraud in the generic drug industry
Sep 16, 2019
Qualy #24 - What are the “ABCs” of Alzheimer’s prevention?
Sep 13, 2019
#70 - David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)
Sep 09, 2019
Qualy #19 - A unifying theory of aging
Sep 05, 2019
#69 - Ronesh Sinha, M.D.: Insights into the manifestation of metabolic disease in a patient population predisposed to metabolic syndrome, and what it teaches us more broadly
Sep 02, 2019
Qualy #16 - How much does cognitive activity ward off cognitive decline?
Aug 30, 2019
#68 - Marty Makary, M.D.: The US healthcare system—why it’s broken, steps to fix it, and how to protect yourself
Aug 26, 2019
Qualy #9 - The importance of exercise for brain health
Aug 20, 2019
#67 - AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more
Aug 19, 2019
Qualy #6 - What are the best lab tests to request specifically for longevity
Aug 14, 2019
#66 - Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer’s disease, and Parkinson’s disease – do all roads lead to mitochondria?
Aug 12, 2019
Qualy #1 - What are Peter's thoughts on alcohol consumption and health?
Aug 06, 2019
#65 - Rick Doblin, Ph.D.: MDMA— the creation, scheduling, toxicity, therapeutic use, and changing public opinion of what is possibly the single most important synthetic molecule ever created by our species
Aug 05, 2019
#64 - Zol Kryger, M.D.: Navigating the sometimes shady world of plastic surgery—understanding potential complications of common procedures and how to reduce your risk by choosing the right doctor and asking the right questions
Jul 29, 2019
#63 - AMA #7: Exercise framework, deadlifting, lower back pain, blood pressure, nootropics, CGM, and more
Jul 22, 2019
#62 - Keith Flaherty, M.D.: Deep dive into cancer—History of oncology, novel approaches to treatment, and the exciting and hopeful future
Jul 15, 2019
#61 - Rajpaul Attariwala, M.D., Ph.D.: Cancer screening with full-body MRI scans and a seminar on the field of radiology
Jul 08, 2019
The one-year anniversary episode with Olivia Attia: Reflecting on the past year and looking forward to exciting times ahead
Jul 02, 2019
#60 - Annie Duke, decision strategist: Poker as a model system for life—how to improve decision making, use frameworks for learning, and apply ‘backcasting’ to boost your odds for future success
Jul 01, 2019
#59 - Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness
Jun 24, 2019
#58 – AMA with sleep expert, Matthew Walker, Ph.D.: Strategies for sleeping more, sleeping better, and avoiding things that are disrupting sleep
Jun 17, 2019
#57 – Rick Rubin, legendary music producer: collaborating with sensitive psyche of greatest living musicians, and his personal story of weight loss and spiritual quest
Jun 10, 2019
#56 - Jocko Willink, retired Navy SEAL, Part II of II: Sleep, fasting, raising kids, discipline, taking ownership, and the impact of war
Jun 03, 2019
#55 - Jocko Willink, retired Navy SEAL, Part I of II: objective, strategy & tactics, leadership, protocols, dealing with death, and applying the many lessons learned from war
May 27, 2019
#54 – Kevin Sayer, CEO of Dexcom: Continuous glucose monitors – impact of food, sleep, and stress on glucose, the unmatched power of CGM to drive behavioral change, and the exciting future of CGM
May 20, 2019
#53 - AMA #6: Fasting framework, vitamin supplementation, antioxidants, time management, problem-solving, and more
May 13, 2019
#52 - Ethan Weiss, M.D.: A masterclass in cardiovascular disease and growth hormone - two topics that are surprising interrelated
May 06, 2019
The Ayrton Senna Episode (re-release): Celebrating the greatest driver in Formula 1 history and the cautionary tales of driven individuals
May 01, 2019
#51 - Robert Sapolsky, Ph.D.: The pervasive effect of stress - is it killing you?
Apr 29, 2019
#50 - AMA #5: calcium scores, centenarian olympics, exercise, muscle glycogen, keto, and more
Apr 22, 2019
#49 – Matthew Walker, Ph.D., on sleep – Part III of III: The penetrating effects of poor sleep from metabolism to performance to genetics, and the impact of caffeine, alcohol, THC, and CBD on sleep
Apr 15, 2019
#48 – Matthew Walker, Ph.D., on sleep – Part II of III: Heart disease, cancer, sexual function, and the causes of sleep disruption (and tips to correct it)
Apr 08, 2019
#47 – Matthew Walker, Ph.D., on sleep – Part I of III: Dangers of poor sleep, Alzheimer's risk, mental health, memory consolidation, and more.
Apr 01, 2019
#46 - Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more
Mar 25, 2019
#45 - AMA #4: sleep, jet lag protocol, autophagy, metformin, and more
Mar 18, 2019
#44 - Jeremy Schaap, ESPN journalist: upsets, doping, triumphs, and the importance of sports
Mar 11, 2019
#43 - Alan Bauman, M.D.: The science of male and female hair restoration - how to protect, enhance, and restore the appearance and health of the hair and scalp
Mar 04, 2019
#42 - Avrum Bluming, M.D., and Carol Tavris, Ph.D.: Controversial topic affecting all women—the role of hormone replacement therapy through menopause and beyond—the compelling case for long-term HRT and dispelling the myth that it causes breast cancer
Feb 25, 2019
#41 - Jake Kushner, M.D.: How to thrive with type 1 diabetes and how everyone can benefit from the valuable insights
Feb 18, 2019
#40 - Tom Catena, M.D.: The world’s most important doctor – to nearly a million patients – saving countless lives in the war-torn and remote villages of Sudan
Feb 11, 2019
#39 - Ted Schaeffer, M.D., Ph.D.: How to catch, treat, and survive prostate cancer
Feb 04, 2019
#38 - Francisco Gonzalez-Lima, Ph.D.: Advancing Alzheimer’s disease treatment and prevention – is AD actually a vascular and metabolic disease?
Jan 28, 2019
#37 - Zubin Damania, M.D.: Revolutionizing healthcare one hilariously inspiring video at a time
Jan 21, 2019
#36 - Eric Chehab, M.D.: Extending healthspan and preserving quality of life
Jan 14, 2019
#35 - Nir Barzilai, M.D.: How to tame aging
Jan 07, 2019
#34 - Sam Harris, Ph.D.: The transformative power of mindfulness
Dec 20, 2018
#33 - Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin
Dec 17, 2018
#32 - Siddhartha Mukherjee, M.D., Ph.D.: new frontiers in cancer therapy, medicine, and the writing process
Dec 10, 2018
#31 - Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease
Dec 03, 2018
#30 - Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease?
Nov 26, 2018
#29 - Apolo Anton Ohno: 8-time Olympic medalist – extreme training, discipline, pursuing perfection, and responding to adversity
Nov 19, 2018
#28 - Mark and Chris Bell: steroids, powerlifting, addiction, diet, training, helping others, documentaries, and living your best life
Nov 12, 2018
#27 - David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging
Nov 05, 2018
#26 - AMA #3: supplements, women’s health, patient care, and more
Oct 29, 2018
#25 - Scott Harrison: transformation, finding meaning, and taking on the global water crisis
Oct 22, 2018
#24 - Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more
Oct 19, 2018
#23 - Tom Dayspring, M.D., FACP, FNLA – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain
Oct 18, 2018
#22 - Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins
Oct 17, 2018
#21 - Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation
Oct 16, 2018
#20 - Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology
Oct 15, 2018
#19 - Dave Feldman: stress testing the lipid energy model
Oct 08, 2018
#18 - Richard Isaacson, M.D.: Alzheimer’s prevention
Oct 01, 2018
#17 - Mike Trevino: life-lessons from ultra-endurance, mindset, hard work, and removing limitations
Sep 24, 2018
#16 - Formula 1 (with Paul Conti): the best drivers, Ayrton Senna, and the cautionary tales of driven individuals
Sep 20, 2018
#15 - Paul Conti, M.D.: trauma, suicide, community, and self-compassion
Sep 17, 2018
#14 - Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system
Sep 10, 2018
#13 - Brett Kotlus, M.D.: How to look younger while you live longer
Sep 03, 2018
#12 - Corey McCarthy: Overcoming trauma, dealing with shame, finding meaning, changing the self-narrative, redemption, and the importance of gratitude
Aug 27, 2018
#11 - AMA #2: the Nothingburger — results from Peter’s week-long fast between two weeks of nutritional ketosis — and answering questions on all things fasting
Aug 23, 2018
#10 - Matt Kaeberlein, Ph.D.: rapamycin and dogs — man’s best friends? — living longer, healthier lives and turning back the clock on aging, and age-related diseases
Aug 20, 2018
#09 - David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity?
Aug 13, 2018
#08 - Tom Bilyeu: nutrition, fasting, meditation, mindset, immortality, and the secret formula of fulfillment
Aug 06, 2018
#07 - Deep Dive: Lp(a) — what every doctor, and the 10-20% of the population at risk, needs to know
Jul 30, 2018
#06 - D.A. Wallach: music, medicine, cancer screening, and disruptive technologies
Jul 23, 2018
#05 - Dom D’Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer
Jul 16, 2018
#04 - AMA #1: alcohol, best lab tests, wearables, finding the right doc, racing, and more
Jul 09, 2018
#03 - Ron Krauss, M.D.: a deep dive into heart disease
Jul 02, 2018
#02 - Rhonda Patrick, Ph.D.: the performance and longevity paradox of IGF-1, ketogenic diets and genetics, the health benefits of sauna, NAD+, and more
Jul 02, 2018
#01 - Tim Ferriss: depression, psychedelics, and emotional resilience
Jul 02, 2018
#00 - Sneak Peek: The Peter Attia Drive
Jun 19, 2018