Mind & Matter

By Nick Jikomes

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Category: Science

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Subscribers: 44
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Episodes: 313

Description

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it.

The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today.


Not medical advice.

At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it.


As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet.


I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint.


My beliefs:


Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi:

  • “Γνῶθι σεαυτόν” (Know thyself)
  • “Μηδὲν ἄγαν” (Nothing in excess)
  • “Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)

Episode Date
This Animal Survives 18 Minutes Without Oxygen | Gary Lewin | 309
Oct 12, 2026
Low Selenium Doubles Your Heart Attack Risk | Lutz Schomburg | 308
Oct 05, 2026
What we're getting WRONG about cane sugar & corn syrup | Kimber Stanhope | 307
Sep 15, 2026
Why Bigger Brains Get More Mutations | Christopher Walsh | 306
Aug 28, 2026
Why THC Users Eat More but Don't Gain Weight | Nephi Stella | 305
Aug 20, 2026
The Gene Variant Linked to Living to 100 | Pinchas Cohen | 304
Aug 12, 2026
Pain, Inflammation, Peptides & Healing | Isaac Chiu | 303
Aug 05, 2026
Mitochondrial Peptide That Doubled Running | David Lee | 302
Jul 30, 2026
What we're getting WRONG about copper peptides | Rahi Sarbaziha | 301
Jul 22, 2026
What we're getting WRONG about the "leaky" aging brain | William Banks | 300
Jul 15, 2026
Too Much Iron and the Aging Brain | Dr. Pamela Maher | 299
Jul 08, 2026
Ozempic Reaches Your Brain in Ways Your Own GLP-1 Can't | Katrin Svensson | 298
Jun 30, 2026
Can Water Low in Deuterium Slow Cancer? | Gábor Somlyai | 297
Jun 18, 2026
Antioxidant Supplements Raised Cancer Rates in Major Trials. Here's Why | Isaac Harris | 296
Jun 11, 2026
Your Body Makes Fructose From Glucose, and It Turns On Fat Storage | Richard Johnson | 295
Jun 04, 2026
How to Lie With Science: Seed Oils & Inflammation | Livestream 1
May 27, 2026
Your Ancestry Changes How Your Body Handles Omega-3 and Omega-6 Fats | Floyd Chilton | 294
May 22, 2026
A Brain Steroid Showed Antidepressant Effects in Bipolar Disorder | Sherwood Brown | 293
May 15, 2026
Most Americans Fall Far Below the Omega-3 Levels Linked to Better Health | Bill Harris | 292
May 08, 2026
Inflammation Doesn't Just Fade. Omega-3s Help Your Body Switch It Off | Philip Calder | 291
May 01, 2026
Reversing Alzheimer's Memory Loss in Mice Without Clearing Plaques | Andrew Pieper | 290
Apr 24, 2026
Parents' Exercise Improves Offspring Metabolism via Sperm and Milk | Kristin Stanford | 289
Apr 17, 2026
Your Vagus Nerve Can Switch Off Inflammation | Kevin Tracey | 288
Apr 10, 2026
Sunlight Curbs Appetite Through a Hormone Unrelated to Vitamin D | Alexis Cowan | 287
Apr 03, 2026
Being Awake Damages Brain Fats, and Sleep Clears Them Out | Amita Sehgal | 286
Mar 29, 2026
BPC-157 Heals Rats but Has Barely Been Tested in Humans | Flynn McGuire | 285
Mar 22, 2026
Why Some People Stay Thin Even When They Overeat | Jens Lund | 284
Mar 13, 2026
Your Mother's Mitochondrial DNA Shapes Metabolism and Disease Risk | Douglas Wallace | 283
Mar 05, 2026
Half Your Cholesterol Exits as Bile Acids, and Diabetes Alters Them | Rebecca Haeusler | 282
Feb 28, 2026
Why Eating at the Wrong Time of Day Adds Weight | Joseph Bass | 281
Feb 23, 2026
A Single Psilocybin Dose Reduced Heroin Seeking in Rats | Stephanie Daws | 280
Feb 19, 2026
Why Women Gain Belly Fat After Menopause | Victoria Vieira-Potter | 279
Feb 14, 2026
A Thin, Hidden Brain Structure Kicks In When Tasks Get Hard | Brian Mathur | 278
Feb 09, 2026
Psychedelics Hit Female Mice Harder but Helped Males More | Javier González-Maeso | 277
Feb 05, 2026
The Enzyme That Fasting, Exercise, Metformin & Ozempic All Switch On | Greg Steinberg | 276
Jan 25, 2026
Even Pasture-Raised Eggs Mostly Reflect Corn and Soy Feed | Ashley Armstrong | 275
Jan 19, 2026
Why the Same Food Spikes One Person's Blood Sugar and Not Another's | Michael Snyder | 274
Jan 14, 2026
Most of What's in Your Food Isn't on the Nutrition Label | Stephan van Vliet | 273
Jan 09, 2026
Why Fructose Acts Like Alcohol on Your Mitochondria | Robert Lustig | 272
Jan 05, 2026
Keto Athletes Performed as Well as Carb Loaders Once Adapted | Andrew Koutnik | 271
Jan 02, 2026
Postpartum Psilocybin Made Mouse Moms Anxious and Harmed Pups | Danielle Stolzenberg | 270
Dec 26, 2025
Soybean Oil Made Mice Fatter Than Coconut Oil | Frances Sladek | 269
Dec 21, 2025
The Fats You Eat Change How Fast Your Body Clock Adjusts | Louis Ptáček | 268
Dec 17, 2025
Ketones Are More Than Fuel. They Act Like Hormones | Dominic D'Agostino | 267
Dec 12, 2025
Too Much Omega-6 Keeps Inflammation From Shutting Off | Ganesh Halade | 266
Dec 07, 2025
Why Observational Studies Keep Getting Nutrition Wrong | George Davey Smith | 265
Dec 02, 2025
Why Your Brain Is Far More Energy-Efficient Than Any Computer | Luis Felipe Barros | 264
Nov 26, 2025
Disrupting How Mitochondria Make Fat Impairs Blood Sugar Control | Sara Nowinski | 263
Nov 18, 2025
Pregnancy Hormones Rewire the Brain for Parenting | Jonny Kohl | 262
Nov 07, 2025
Your Cells Swap Mitochondria, and High-Fat Diets Disrupt It | Jon Brestoff | 261
Nov 02, 2025
Your Health Depends on How Easily Energy Flows | Martin Picard & Nirosha Murugan | 260
Oct 28, 2025
Menstrual Cycles Still Sync With the Moon, but Less Since LEDs | Charlotte Förster | 259
Oct 19, 2025
Hundreds of Tiny DNA Switches Reshaped the Human Pelvis | Terence Capellini | 258
Oct 15, 2025
You Need Sleep Because Your Mitochondria Leak | Gero Miesenböck | 257
Oct 10, 2025
Mouth Bacteria Hide Inside the Plaques That Cause Heart Attacks | Pekka Karhunen | 256
Oct 05, 2025
How SSRIs and Statins Can Drain Your Cells' Energy | Chris Masterjohn | 255
Sep 30, 2025
Your ApoE Gene Changes How Your Brain Handles Stress, Diet and Radiation | Jacob Raber | 254
Sep 26, 2025
A Mother's Obesity Reprograms Her Offspring's Liver Immune Cells in Mice | Elvira Mass | 253
Sep 21, 2025
Psilocybin Extended Cell Lifespan and Helped Old Mice Live Longer | Louise Hecker | 252
Sep 16, 2025
Low-Protein Diets Make Mice Eat More and Burn More | Chris Morrison | 251
Sep 12, 2025
Cells and Tissues Can Learn and Remember Without a Brain | Michael Levin | 250
Sep 07, 2025
Too Much Fructose Impaired Brain Cleanup, Caused Anxiety in Young Mice | Justin Perry | 249
Sep 03, 2025
Does Acetaminophen Trigger Autism in Susceptible Babies? | William Parker | 248
Aug 29, 2025
LDL Cholesterol Binds Bacteria. Is Lowering It Always Good? | Uffe Ravnskov | 247
Aug 25, 2025
Your Appendix Isn't Useless. It's a Safe House for Gut Bacteria | William Parker | 246
Aug 19, 2025
Your Cannabinoid System Evolved to Store Energy for the Future | Giovanni Marsicano | 245
Aug 13, 2025
Oxidized Seed Oil Fats May Matter More for Heart Disease Than LDL | Tucker Goodrich | 244
Aug 07, 2025
Hunter-Gatherers Burn About the Same Calories as Office Workers | Herman Pontzer | 243
Aug 01, 2025
Near-Infrared Sunlight Helps Your Mitochondria Make Energy | Robert Fosbury | 242
Jul 27, 2025
Neurons Burn Fat for Fuel, Overturning a Long-Held Brain Dogma | Timothy Ryan | 241
Jul 23, 2025
High-Fiber Food Beat Fecal Transplants at Restoring the Gut in Mice | Eugene Chang | 240
Jul 18, 2025
Some People Thrive on 4-6 Hours of Sleep. Their Genes Explain Why | Ying-Hui Fu | 239
Jul 13, 2025
Male Testosterone Fell About 20% in 17 Years. What It Means | Charles Cornish-Dale | 238
Jul 08, 2025
Meal Timing Tripled Calorie Restriction's Lifespan Gain in Mice | Joseph Takahashi | 237
Jul 04, 2025
Your Cells Patch Their Own Wounds With Self-Assembling Rings | Bill Bement | 236
Jun 29, 2025
Mice Learn Just by Exploring, and It Speeds Up Later Training | Marius Pachitariu | 235
Jun 26, 2025
Blocking a Brain Fat Carrier May Ease Anxiety Without Addiction | Steven Laviolette | 234
Jun 16, 2025
Seed Oils Add an Evolutionarily New Load of Omega-6 Fat | Brian Kerley | 233
Jun 11, 2025
SSRIs Can Cause Sexual Dysfunction That Lasts Years After Stopping | David Healy | 232
Jun 05, 2025
Lemon Juice Doesn't Activate Magic Mushrooms. The Real Chemistry | Andrew Chadeayne | 231
May 25, 2025
Psychedelics May Calm Stress-Driven Inflammation Around the Brain | Michael Wheeler | 230
May 20, 2025
Linoleic Acid Fuels an Aggressive Breast Cancer | Nikos Koundouros & John Blenis | 229
May 15, 2025
Your Memories Aren't Fixed Recordings in the Brain | György Buzsáki | 228
May 10, 2025
Your Cells Give Off Faint Light, and Cancer Cells Glow Differently | Nirosha Murugan | 227
May 05, 2025
One Dose of Psilocybin Rewires Mouse Brain Connections for Weeks | Alex Kwan | 226
May 01, 2025
Diet Surveys Undercount What People Eat, Skewing Nutrition Science | John Speakman | 225
Apr 26, 2025
Is Cancer a Metabolic Disease, Not a Genetic One? | Thomas Seyfried | 224
Apr 23, 2025
High LDL on Keto Didn't Speed Plaque Growth in Lean, Healthy People | Matthew Budoff | 223
Apr 19, 2025
Body Weight Is 40-70% Heritable. Here's What That Doesn't Mean | Giles Yeo | 222
Apr 15, 2025
He Lost 133 Pounds in 11 Months With Sunlight and Cold. His Theory | Jack Kruse | Ep 221
Apr 11, 2025
A Cannabis Compound Protected Mitochondria and Memory in Aging Mice | Pamela Maher | 220
Apr 08, 2025
Shamanism Appears Across Cultures. It's Not Just Early Religion | Manvir Singh | 219
Apr 04, 2025
Pesticides Raise Parkinson's Risk, While Caffeine and Nicotine Lower It | Gary Miller | 218
Mar 31, 2025
Elephants May Call Each Other by Name | Mickey Pardo | 217
Mar 27, 2025
Low-Dose Aspirin May Help Stop Cancer From Spreading | Rahul Roychoudhuri | 216
Mar 23, 2025
Fructose Made Tumors Grow 4x Faster in Mice, by Way of the Liver | Gary Patti | 215
Mar 19, 2025
Changing Your Diet Reshapes Your Gut Microbes Within One Day | Peter Turnbaugh | 214
Mar 14, 2025
Only 1 in 5 Overweight People Get Type 2 Diabetes. Here's Why | Scott Soleimanpour | 213
Mar 10, 2025
Most Published Research Findings Are False, and the Math Still Holds | John Ioannidis | 212
Mar 05, 2025
Your Smartwatch Can Detect Illness Days Before Symptoms | Michael Snyder | 211
Mar 01, 2025
Sweden Avoided Lockdowns and Saw Lower Excess Mortality | Martin Kulldorff | 210
Feb 26, 2025
Thyroid Hormone Sets Your Metabolism and May Affect Lifespan | Diana van Heemst | 209
Feb 14, 2025
Glyphosate Can Reach the Brain, and Choline May Protect It | Ramon Velazquez | 208
Feb 08, 2025
Sugars Do More Than Fuel Cells. They Help Proteins Work | Eva Morava | 207
Feb 03, 2025
Medieval Church Marriage Rules Helped Create Western Individualism | Joseph Henrich | 206
Jan 29, 2025
Much Chronic Disease Could Be Caught and Prevented Before Symptoms | Lee Hood | 205
Jan 24, 2025
The Same Food Can Help One Person and Harm Another | Momo Vuyisich | 204
Jan 17, 2025
Mothers Pass Gut Microbes to Their Babies at Birth | Nicola Segata | 203
Jan 12, 2025
Scientists Still Don't Know Why Animals Sleep | Vlad Vyazovskiy | 202
Jan 06, 2025
A Strawberry's Smell Comes From a Tiny Fraction of Its Molecules | Alex Wiltschko | 201
Dec 22, 2024
Colon Tumors Carry Inflammation That Never Switches Off | Tim Yeatman & Ganesh Halade | 200
Dec 17, 2024
Clovis People Got 35-40% of Their Protein From Mammoths | Ben Potter & Jim Chatters | 199
Dec 12, 2024
Myocarditis and Menstrual Changes Stand Out in mRNA Shot VAERS Data | Jessica Rose | 198
Dec 07, 2024
Did Snake Venom Rituals Spark Self-Awareness in Women First? | Andrew Cutler | 197
Dec 04, 2024
Early-Life Stress Can Tune How Strongly You React to Stress Later | Rosemary Bagot | 191
Nov 30, 2024
Cannabis Can Trigger a Real, Drug-Induced Psychosis | Jibran Khokhar | 190
Nov 26, 2024
Pfizer's Vaccine Plasmid Carries Four SV40 Virus Components | Kevin McKernan | 196
Nov 21, 2024
Your Skin Makes Its Own Melatonin to Protect Itself | Andrzej Slominski | 189
Nov 18, 2024
Psilocybin Knocks Brain Cells Out of Sync With Their Neighbors | Joshua Siegel | 188
Nov 13, 2024
Heavy Screen Use Can Cause Autism-Like Symptoms That Fade Offline | Richard Cytowic | 187
Nov 10, 2024
High Protein Doesn't Hurt Healthy Kidneys. That's a Myth | Thomas Weimbs | 186
Nov 06, 2024
Oreos Lowered His LDL Twice as Much as a Statin. What It Means | Nick Norwitz | 195
Oct 31, 2024
Sugar Can Drive Withdrawal. That Doesn't Mean Everyone Gets Hooked | Nicole Avena | 185
Oct 30, 2024
BPA Doesn't Just Spike Insulin. It Retrains the Pancreas | Angel Nadal | 184
Oct 27, 2024
The Mice That Lost the Most Weight on Diets Lived Shorter Lives | Gary Churchill | 183
Oct 23, 2024
Your Brain Does Its Thinking Outside the Language Network | Ev Fedorenko | 182
Oct 19, 2024
Focused Ultrasound Briefly Opens the Blood-Brain Barrier, No Surgery | Nir Lipsman | 181
Oct 15, 2024
Hunger and Fullness Come From Two Opposing Sets of Brain Cells | Marcelo Dietrich | 180
Oct 11, 2024
The Oldest Dated Cave Art Is at Least 51,200 Years Old | Maxime Aubert | 179
Oct 08, 2024
Ask Me Anything 1 | Nick Jikomes
Sep 27, 2024
Mice Missing Certain Gut Bacteria Gained Weight Faster | June Round | 178
Sep 20, 2024
Blocking Opioid Receptors Shrinks the Placebo Effect | Gregory Scherrer | 177
Sep 15, 2024
Crisco Began as a Use for Cottonseed, a Cotton Industry Waste | Steven Rofrano | 194
Sep 11, 2024
Obesity May Be Driven by Insulin, Not Just Excess Calories | Gary Taubes | 176
Sep 06, 2024
Your Blood Proteins Can Reveal Your Biological Age | Austin Argentieri | 175
Sep 03, 2024
Brown Fat Burns Energy. Most of Your Fat Just Stores It | Sean Hartig | 174
Aug 29, 2024
Psychedelics Raise the Brain's Entropy, His Theory Says | Robin Carhart-Harris | 173
Aug 24, 2024
Vitamin D Made Mice More Resistant to Cancer, Through the Gut | Caetano Reis e Sousa | 172
Aug 21, 2024
Neocortex and Cerebellum Evolved in Lockstep in Primates | Robert Barton | 171
Aug 18, 2024
Psilocybin Amplified Amygdala Reactions in Female Rats, Not Males | Melissa Herman | 170
Aug 14, 2024
Forming a Memory Changes How DNA Is Packaged in Neurons | Giulia Santoni | 169
Aug 09, 2024
A Predator Nearby Switches Off Sleep Through the Stress System | Luis de Lecea | 168
Aug 05, 2024
Skunky Cannabis Smell Comes From Sulfur Compounds, Not Terpenes | Iain Oswald | 167
Jul 26, 2024
Diet and Crowding Shape the Rise and Fall of Civilizations | Rudyard Lynch | 193
Jul 19, 2024
Genetic Drift, Not Just Selection, Built Cellular Complexity | Michael Lynch | 166
Jul 14, 2024
Brain DHA Builds Up Early, Then Plateaus by About Age Two | Richard Bazinet | 165
Jul 10, 2024
More Omega-3 in the Skin Meant Less Sunburn in a Human Study | Tucker Goodrich | 192
Jun 30, 2024
Dopamine Signals Learning, Not Just Pleasure | Melissa Sharpe | 164
Jun 26, 2024
Psychedelic Trials Can't Truly Be Blinded. Why That Matters | Boris Heifets | 163
Jun 22, 2024
Addiction Rewires the Same Synapses That Learning Uses | Robert Malenka | 162
Jun 16, 2024
His Lab Paired GLP-1 With an NMDA Blocker in One Drug | Christoffer Clemmensen | 161
Jun 12, 2024
For Hunter-Gatherers, Fat Often Matters More Than Meat | Eugene Morin | 160
Jun 01, 2024
Pain Spreads Between Mice After an Hour Together. So Does Relief | Monique Smith | 159
May 23, 2024
Fasting's Seizure Control Led to the Ketogenic Diet in the 1920s | Dominic D'Agostino | 158
May 16, 2024
He Taught Medical Students Things He Now Says Were Wrong | Robert Lufkin | 157
May 09, 2024
Resilience Is Built From Skills You Can Practice | Stephen Sideroff | 156
May 03, 2024
Dialing Down Mitochondria in Neurons Made Worms Live Longer | Andrew Dillin | 155
Apr 29, 2024
Light Skin Evolved After Humans Had Already Left Africa | Eske Willerslev | 154
Apr 24, 2024
She Treats Bipolar Disorder and Schizophrenia With Diet | Georgia Ede | 153
Apr 19, 2024
Two Buds From One Plant Don't Share One Chemical Profile | Ryan Vandrey | 152
Apr 12, 2024
Resveratrol Never Lived Up to the Red Wine Longevity Story | Matt Kaeberlein | 151
Apr 07, 2024
Briefly Silencing the Retinas Restored Vision in Amblyopic Animals | Mark Bear | 150
Apr 03, 2024
He Sequenced Vaccine Vials and Found Pfizer's Plasmid DNA Inside | Kevin McKernan | 149
Mar 30, 2024
A 100-Gram Protein Meal Beat 25 Grams for Muscle Protein Synthesis | Luc van Loon | 148
Mar 27, 2024
Naltrexone Altered Ketamine's Brain Effects in Male Rats Only | Tommaso Di Ianni | 147
Mar 22, 2024
Near-Infrared Sunlight Penetrates Skin and Skull, Reaching the Brain | Scott Zimmerman | 146
Mar 19, 2024
Low Doses of Tributyltin Made Mice Fat, and Their Descendants Too | Bruce Blumberg | 145
Mar 14, 2024
An Omega-6 Fat That Rises During Fasting Dampened Inflammation | Clare Bryant | 144
Mar 10, 2024
Sugar and Fat Activate Separate Sets of Vagus Nerve Cells | Will de Lartigue | 143
Mar 05, 2024
DMT Rose About Sixfold in Rat Brains After Cardiac Arrest | Nicolas Glynos | 142
Feb 29, 2024
Domesticated Finches Sang More Variable Songs Than Wild Ones | Terrence Deacon | 141
Feb 24, 2024
Cold, High Places Have Less Obesity. He Says Lifestyle Isn't Why | Robert Lustig | 140
Feb 17, 2024
After 12 to 14 Hours Without Food, Your Body Switches to Ketones | Mark Mattson | 139
Feb 14, 2024
New Body Forms Evolve by Rewiring Gene Switches, Not New Genes | Sean B. Carroll | 138
Feb 09, 2024
Some Psychedelics Fully Blocked Asthma Inflammation in Rats | David & Charles Nichols | 137
Feb 06, 2024
Omega-6 Rose From 1% to Nearly 12% of US Calories Since 1865, He Says | Chris Knobbe | 136
Jan 23, 2024
Ancel Keys Was Brilliant, but Made Enormous Mistakes, He Argues | Orrin Devinsky | 135
Jan 10, 2024
Modern Diets Can Carry 20 Times More Omega-6 Than Omega-3 | Artemis Simopoulos | 134
Jan 03, 2024
A Quarter of Breast Milk's Dry Weight Is Sugar Babies Can't Digest | Carolina Tropini | 133
Dec 20, 2023
In Mice, Dietary Fat Was the Only Macronutrient That Drove Fat Gain | John Speakman | 132
Dec 05, 2023
A Low-Fat, High-Carb Diet Shifted 1 in 4 People to Riskier Small LDL | Ronald Krauss | 131
Dec 04, 2023
Multitasking Is Mostly an Illusion. Your Brain Just Switches Tasks | Tobias Egner | 130
Nov 05, 2023
Deep Voices Likely Evolved More to Intimidate Men Than to Attract Women | David Puts | 129
Oct 22, 2023
Constipation and Poor Sleep Often Come Before Parkinson's Tremor | Moses Chao | 128
Oct 16, 2023
Psilocybin Microdoses Every Other Day Changed Rat Brains and Behavior | Mikael Palner | 127
Oct 11, 2023
A Species With a Third of Our Brain Size May Have Buried Its Dead | John Hawks | 126
Aug 28, 2023
The Brain's Immune Cells Help Control Anxiety and Compulsive Grooming | Mario Capecchi | 125
Aug 21, 2023
The Estradiol in Birth Control Pills May Help Verbal Memory | Adriene Beltz | 124
Aug 15, 2023
Runner's High Likely Comes From Endocannabinoids, Not Endorphins | Matthew Hill | 123
Aug 10, 2023
Daily Taurine From Middle Age Extended Mouse Lifespan 10 to 12% | Vijay Yadav | 122
Aug 02, 2023
Five Psychedelics Reopened a Social Learning Window in Adult Mice | Gül Dölen | 121
Jul 19, 2023
Therapy and SSRIs Work About Equally, Each Helping 30 to 50% of People | Alan Davis | 120
Jul 11, 2023
A Receptor 'Lid' Traps LSD for Hours, Helping Explain Its Long Trips | Bryan Roth | 119
Jul 06, 2023
Psychedelics Heal Through the Trip Itself, Not Just the Molecule | Dennis McKenna | 118
Jun 28, 2023
Anxiety and Depression Definitions Overlap About 80% in the DSM | Daniel Karlin | 117
Jun 09, 2023
About 80% of Store-Bought Avocado Oils Tested Were Oxidized or Impure | Selina Wang | 116
Jun 01, 2023
Protein Given During Sleep Still Built Muscle in Older Adults | Luc van Loon | 115
May 25, 2023
Smell Is a Good Freshness Test for Cannabis. Key Compounds Fade Fast | Iain Oswald | 114
May 08, 2023
Vaping Lung Injuries Were Tied to Vitamin E Acetate Used to Dilute THC | Echo Rufer | 113
May 02, 2023
Dementia May Begin When Neurons Run Short of Oxygen, His Model Says | Nathan Price | 112
Apr 13, 2023
Your Accent Was Set in Infancy, When Your Brain Merged Unused Sounds | Dan Brady | 111
Apr 05, 2023
Isolation Nearly Halted New Neuron Growth in Mice. Novelty Restarted It | Rusty Gage | 110
Mar 20, 2023
Inflated THC Labels Are a Bigger Problem Than Pesticides on the Shelf | Nick Mosley | 109
Mar 17, 2023
Mind & Matter Podcast | Nick Jikomes, PhD | Neuroscience, Psychedelics, Psychology, Psychology, Molecular Biology, Genetics, Evolution, Metabolism, Nutrition, Biotech
Mar 14, 2023
Voles Without Oxytocin Receptors Still Formed Strong Pair Bonds | Devanand Manoli | 108
Mar 08, 2023
Your Brain Doesn't Perceive, Then Think, Then Act. It Runs Control Loops | Paul Cisek | 107
Feb 27, 2023
Diets Under 15% Protein Made People Overeat | Stephen Simpson & David Raubenheimer | 106
Feb 20, 2023
Obesity Surgery Works via Gut Hormones, Not a Smaller Stomach | Christoffer Clemmensen | 105
Feb 07, 2023
Sunlight Lowers Blood Pressure Through Nitric Oxide, Not Vitamin D | Richard Weller | 104
Jan 23, 2023
Gut Bacteria Boost the Dopamine Reward From Exercise in Mice | Christoph Thaiss | 103
Jan 17, 2023
Swap One Atom in LSD and You Get a Drug That Isn't Psychoactive | Ryan Gumpper | 102
Jan 12, 2023
Ambien Has Woken Some Patients From Long Minimally Conscious States | Alex Proekt | 101
Dec 26, 2022
Twitter Quietly Limited His Reach Over His COVID Policy Views | Jay Bhattacharya | 100
Dec 19, 2022
Rats Learned to Seek Water When Their Transplanted Human Neurons Fired | Sergiu Pasca | 99
Dec 15, 2022
Serotonin Got Tied to Mood by Antidepressants, Not by Discovery, He Says | Zach Mainen | 98
Nov 28, 2022
SARS-CoV-2's Cut-Site Map Looks the Most Engineered of 1,491, He Says | Alex Washburne | 97
Nov 21, 2022
In Her LSD Microdosing Trial, the Placebo Group Improved Just as Much | Harriet de Wit | 96
Nov 15, 2022
Life Holds Off Decay by Pairing Two Processes That Check Each Other | Terrence Deacon | 95
Nov 07, 2022
Rats With 99% of Their Dopamine Gone Still Liked Sweet Tastes | Kent Berridge | 94
Oct 31, 2022
In His Study, CBD Blunted the Memory Hit From THC | Amir Englund | 93
Oct 24, 2022
Cutting Branched-Chain Amino Acids Extended Male Mouse Lifespan ~30% | Dudley Lamming | 92
Oct 18, 2022
People Outside Africa Carry Roughly 1.5 to 2.5% Neanderthal DNA | Razib Khan | 91
Oct 11, 2022
Cocaine Rewired Reward Synapses in Mice. Ketamine Didn't | Christian Lüscher | 90
Oct 04, 2022
Castrated Male Mice Regained the Ability to Fight When Given Estrogen | David Anderson | 89
Sep 28, 2022
Antidepressants Beat Placebo by About 2 Points on a 52-Point Scale | Joanna Moncrieff | 88
Sep 21, 2022
Homelessness Nonprofits Develop an Interest in Surviving, He Says | Leighton Woodhouse | 87
Sep 15, 2022
Chimpanzees Reunite Each Night With a Drumming and Chorusing Ritual | Michael Winkelman | 86
Aug 31, 2022
Cut Magic Mushrooms Turn Blue as Psilocin Links Into Chains | Dirk Hoffmeister | 85
Aug 25, 2022
Hurricanes Aren't Getting More Frequent. The Debate Is Over Intensity | Judith Curry | 84
Aug 18, 2022
Free Samples, Not TV Ads, Are Pharma's Biggest Marketing Spend, He Says | David Cohen | 83
Aug 11, 2022
Cells Remember Past Inflammation by Keeping Stress Genes Open | Shruti Naik | 82
Aug 04, 2022
Rats Deprived of Play Grew Up Hyper-Aggressive, but Only the Males | Margaret McCarthy | 81
Jul 28, 2022
No Infected Animal Was Found in Wuhan's Market, Unlike With SARS in 2003 | Matt Ridley | 80
Jul 21, 2022
His Startup Bets Shorter-Acting Psychedelics Are the Fastest to Clinics | Sam Banister | 79
Jul 14, 2022
If Your Identical Twin Has Schizophrenia, Your Own Risk Is About 50% | Kevin Mitchell | 78
Jul 07, 2022
Some Smokers Lost All Craving for Cigarettes After a Stroke | Michael Fox | 77
Jun 30, 2022
Fasted People Running on Ketones Felt Fine at Very Low Blood Sugar | Dominic D'Agostino | 76
Jun 23, 2022
Firewalkers' Heartbeats Synced With Family Watching, Not Tourists | Dimitris Xygalatas | 75
Jun 16, 2022
MDMA Can Make It Harder to Read Fear in Other People's Faces | Manoj Doss | 74
Jun 09, 2022
The Amygdala Detects Threats. The Feeling of Fear Comes Later, He Says | Joseph LeDoux | 73
Jun 02, 2022
A 90%-Fat Ketogenic Diet Protected Mice From Colon Tumors | Maayan Levy | 72
May 26, 2022
Nobody Likes Pure THC, and Its Main Side Effect Is Paranoia | Andrew Chadeayne | 71
May 19, 2022
A Woman's Hair Lost Its Color as Stress Rose, Then Regained It | Martin Picard | 70
May 12, 2022
The Best Anti-Aging Fixes Extend Mouse Lifespan Only 10 to 30% | Leonard Guarente | 69
May 05, 2022
High Incubation Heat Turns Genetically Male Bearded Dragons Female | Blanche Capel | 68
Apr 28, 2022
Most People Exposed to Trauma Never Develop PTSD | Rachel Yehuda | 67
Apr 21, 2022
People Are Easy to Fool Because They Want to Be, He Argues | Robert Greene | 66
Apr 14, 2022
Evolution Tuned Our Senses for Fitness, Not for Seeing the Truth | Donald Hoffman | 65
Apr 07, 2022
Resveratrol Extended Life Only in Obese Mice, Not Healthy Ones | Joe Baur | 64
Mar 31, 2022
A Young Mouse's Microbiome Reversed Some Signs of Brain Aging in Old Mice | John Cryan | 63
Mar 23, 2022
On a Low Dose of MDMA, Asocial Octopuses Turned Playful and Social | Gul Dolen | 62
Mar 16, 2022
Wuhan Numbers Showed Over a 1,000-Fold COVID Death-Risk Gap by Age | Martin Kulldorff | 61
Mar 07, 2022
Is Everything Made of Consciousness? | Bernardo Kastrup | 60
Mar 02, 2022
Epilepsy Patients Taking CBD Tested COVID-Positive About Half as Often | Marsha Rosner | 59
Feb 23, 2022
In Most CBD Cannabis Lines, the THC Gene Is Deleted Entirely | Kevin McKernan | 58
Feb 15, 2022
She Says There Is No Sci-Hub Team. She Has Always Run It Alone | Alexandra Elbakyan | 57
Feb 10, 2022
Probiotics After Antibiotics Can Delay Your Gut's Natural Recovery | Suzanne Devkota | 56
Feb 03, 2022
Rats on Junk Food Did Worse on Memory Tests Within Days | Amy Reichelt | 55
Jan 27, 2022
Dinosaurs Grew Far Faster Than Any Other Reptile We Know Of | Paul Barrett | 54
Jan 20, 2022
A Study Found 28% THC Didn't Feel Stronger Than 22 to 25% | Reggie Gaudino | 53
Jan 13, 2022
Lab Rodents Show More Pain When a Woman Runs the Test Than a Man | David Roberson | 52
Jan 06, 2022
Past Dunbar's ~150 People, Organizations Turn Political, He Argues | Alexandros Marinos | 51
Dec 30, 2021
These Vaccine Vials Get a Glass Layer ~1,000x Thinner Than a Hair | Christopher Weikart | 50
Dec 23, 2021
The Twin Who Used More Cannabis Showed No Extra Psychosis Signs | Jonathan Schaefer | 49
Dec 16, 2021
Injury to the Newborn Cerebellum Raises Autism Risk 30 to 40 Fold | Sam Wang | 48
Dec 09, 2021
A Beef Stew Spiked His Blood Sugar Twice as Much as Ice Cream | Nathan Price | 47
Dec 02, 2021
Depression Shrivels Neurons, and Psychedelics Regrow Them | David Olson | 46
Nov 24, 2021
In 2012, Six Miners Fell Sick in a Bat Cave and Three of Them Died | Alina Chan | 45
Nov 16, 2021
A Brain 'Complexity' Score Reveals Awareness in Unresponsive Patients | Anil Seth | 44
Nov 11, 2021
Dreams May Exist to Keep Your Brain From Overfitting Reality | Erik Hoel | 43
Nov 04, 2021
CBD Can Cancel Out THC's Anxiety and Psychosis Effects | Steven Laviolette | 42
Oct 27, 2021
Swallowed Cannabinoids Deliver Only About 10% to Your Bloodstream | Saoirse O'Sullivan | 41
Oct 21, 2021
Most People Who Use an Addictive Drug Never Become Addicted | Christian Luscher | 40
Oct 14, 2021
SARS-CoV-2 Lacks the Telltale Signs of a Natural Origin, He Argues | Nicholas Wade | 39
Sep 30, 2021
Homo Naledi Had a Tiny Brain Yet May Have Buried Its Dead | Lee Berger | 38
Sep 24, 2021
Before the Eyes Open, the Brain Rehearses Vision With Spontaneous Waves | Michael Crair | 37
Sep 17, 2021
Dating Apps Give 20% of Men 80% of Women's Interest | Heather Heying & Bret Weinstein | 36
Sep 09, 2021
One Brain Rhythm Can Detach Your Sense of Self From Your Body | Karl Deisseroth | 35
Sep 03, 2021
At Yale, More Students Come From the Top 1% Than the Bottom 60% | Rob Henderson | 34
Aug 27, 2021
He Synthesized Much of the LSD Used in Modern Research Studies | David Nichols | 33
Aug 19, 2021
The Alpha Variant Likely Evolved Inside One Chronically Infected Person | Sarah Otto | 32
Aug 11, 2021
The Brain Runs Reward and Punishment on Two Separate Systems | Aaron Gruber | 31
Aug 06, 2021
A Single Dose of Psilocybin Grew New Neural Connections Within Hours | Alex Kwan | 30
Jul 16, 2021
Ketamine Lifts Depression in Hours, While SSRIs Take Weeks | Lisa Monteggia | 29
Jul 09, 2021
A Molecule's Complexity Alone Can Reveal Whether Life Made It | Lee Cronin | 28
Jun 25, 2021
Genome Sequencing Fell From $3 Billion to Under $1,000 | George Church | 27
Jun 18, 2021
After MDMA Therapy, 67% No Longer Qualified as Having PTSD | Berra Yazar-Klosinski | 26
Jun 11, 2021
On DMT, the Brain Slips Into Something Much Like Dreaming | Chris Timmermann | 25
Jun 04, 2021
About 70% of Your Immune Cells Live in Your Gut | Emeran Mayer | 24
May 28, 2021
Six Years After a Psilocybin Trial, He Still Hasn't Had a Drink | Jon Kostakopoulos | 23
May 21, 2021
Mouse Behavior Breaks Into About 60 Reusable 'Syllables' | Alex Wiltschko | 22
May 14, 2021
Scientists Still Can't Agree on a Definition of Life, He Says | Carl Zimmer | 21
May 07, 2021
Only Humans Use True Symbols, and That Reshaped Our Brains | Terrence Deacon | 20
Apr 29, 2021
CBD Lowered Craving and Anxiety in People With Heroin Addiction | Yasmin Hurd | 19
Apr 23, 2021
SARS-CoV-2 Was Well Adapted to Humans From the Very Start, She Says | Alina Chan | 18
Apr 16, 2021
Top Journals Reject About 98% of the Papers Submitted | Michael Eisen | 17
Apr 09, 2021
Wake Someone During REM and About 80% Will Report a Dream | Bob Stickgold | 16
Apr 02, 2021
Chemical Analysis of Magic Mushrooms of the Pacific Northwest | Michael Beug | Bonus Episode
Mar 31, 2021
Cannabis Use Has Jumped Over 400% Among People 55 and Older | Ziva Cooper | 15
Mar 26, 2021
He Engineers Yeast to Brew Cannabinoids Without the Plant | Jeff Ubersax | 14
Mar 20, 2021
Monk Parakeets Appear to Know the Whole Group's Pecking Order | Elizabeth Hobson | 13
Mar 12, 2021
Double an Animal's Size and Each Cell Needs Only 75% as Much Energy | Geoffrey West | 12
Mar 04, 2021
The Pain-Free Woman Had the Highest Anandamide He Ever Measured | Matthew Hill | 11
Feb 27, 2021
A Gene Inherited From Neanderthals Cuts COVID Risk by About 30% | John Hawks | 10
Feb 19, 2021
Whole-Plant CBD Controlled Seizures at 1/5 the Dose of Pure CBD | Ethan Russo | 9
Feb 15, 2021
Block the 5-HT2A Receptor and a Classic Psychedelic Stops Working | Katrin Preller | 8
Feb 06, 2021
Ibogaine Is Real Psychotherapy: The Most Logical Night of His Life | Hamilton Morris | 6
Feb 01, 2021
Salvia's Molecule Is the Most Potent Natural Psychedelic Known | Peter Addy | 7
Jan 30, 2021
Cannabis Dependency Hits About 9% of Regular Users, Like Caffeine | Jon Page | 5
Jan 16, 2021
About a Third of All Prescribed Drugs Act on One Receptor Family | Bryan Roth | 4
Jan 09, 2021
Chance, Not Just Selection, Shapes Who You Are, He Argues | Sean B. Carroll | 3
Jan 01, 2021
A Psychedelic Was 100x Stronger Than a Steroid Against Inflammation | Charles Nichols | 2
Dec 25, 2020
An Ancient Greek Shrine in Spain Tested Positive for Ergotized Beer | Brian Muraresku | 1
Dec 14, 2020