Longevity by Design

By InsideTracker

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Description

Longevity by Design is a podcast for individuals looking to experience a longer, healthier life. In each episode, Dr. Gil Blander joins a co-host and an industry expert to explore a personalized health journey. The show helps you access science-backed information, unpack complicated concepts, learn what’s on the cutting edge of longevity research and the scientists behind them. Tune into Longevity by Design and see how to add years onto your life...and life onto your years.

Episode Date
Dr. Filipe Gomes Cabreiro—How The Gut Microbiome Impacts Longevity
2746

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Filipe Cabreiro. An expert in the gut microbiome and principal investigator at The Cabreiro Lab, Dr. Cabreiro discusses the latest science on the connection between gut microbial and healthy aging. Join us to learn how to improve microbial diversity and assess gaps in the knowledge that are currently under investigation.

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Sep 21, 2022
Dr. Matt Johnson—Continuous Glucose Monitoring in Healthy People
2911

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Matt Johnson. Dr. Johnson is the Director of Clinical Research at Dexcom—a leading company in diabetes care through the use of continuous glucose monitoring. With extensive knowledge in diabetes, metabolic health, and exercise physiology, Dr. Johnson talks through his research and gives insight into the latest science in the field of longevity. 

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Sep 07, 2022
Dr. Dudley Lamming—Surprising Findings From Protein-Restriction Studies
2757

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Dudley Lamming, an Associate Professor at the University of Wisconsin-Madison School of Medicine in the Division of Endocrinology, Diabetes, and Metabolism. Tune in as Dr. Lamming discusses his research on protein restriction and fasting. As the principal investigator of his lab, Dr. Lamming has extensive knowledge of nutrient signaling pathways and how dietary patterns promote health. Tune in as Dr. Lamming discusses the latest science in the field.

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Aug 24, 2022
Dr. Mitch Roslin—Preventative vs Reactive Scientific Approach to Weight Management
3747

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Mitch Roslin, Chief of Bariatric Surgery at Lenox Hill Hospital in New York City. During this conversation with Dr. Mitch Roslin, he talks in detail about the obesity epidemic—he touches on taking a preventative, upstream approach, causes, consequences, and everything in between. Dr. Roslin shares his experience as a bariatric surgeon, and the important role this surgery has on obesity treatment and outcomes.

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

This episode is intended to share information on weight management. The subject matter may be distressing, not appropriate, or triggering for some individuals. Please proceed with caution if you continue to listen to this episode.


Aug 10, 2022
Dr. Krista Varady—Does Human Research on Intermittent Fasting Support Longevity?
2637

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Krista Varady, Professor of Nutrition at the University of Illinois, Chicago. Research on intermittent fasting is largely conducted in cellular and animal models. Dr. Krista Varady is one of few scientists to conduct intermittent fasting clinical trials in humans. Tune in as Dr. Krista Varady discusses the latest science in the field. 

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Jul 27, 2022
Dr. Ronald Krauss—A Proactive Approach to Heart Health
3233

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Ronald Krauss, Professor of Medicine at UCSF, and Adjunct Professor of Nutritional Sciences at UC Berkeley. Tune in as Dr. Ronald Krauss discusses the contributing factors to atherosclerosis, the biomarkers most associated with heart disease, and components of a heart-healthy diet.

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Jul 06, 2022
Dr. Roger Fielding—The Prevention of Age-Related Muscle Loss
2552

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Roger Fielding, Associate Director of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University. Tune in as Dr. Roger Fielding describes how proper nutrition and being physically active build muscle and prevent age-related muscle loss. 

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Jun 22, 2022
Dr. Mariette Abrahams—Personalized Nutrition for Sustainable Change
3709

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Mariette Abrahams, CEO, and Founder of Qina, the first hub for data insights on Personalized Nutrition. Tune in as Mariette Abrahams discusses personalized nutrition and how to turn simple actions into sustainable health changes. 

For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Jun 08, 2022
Dr. George Church—Gene Therapy and Aging
1743

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. George Church, Professor of Genetics at Harvard Medical School. Tune in as Dr. George Church discusses the many roles of gene therapy, including its ability to reverse age-related diseases.

For science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

May 18, 2022
Dr. Eric Verdin—The Effect of Food on Longevity
3626

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eric Verdin, the President and Chief Executive Officer of the Buck Institute for Research on Aging. Tune in as Dr. Eric Verdin discusses nutrient sensing, epigenetic regulation, and recent research on the impact of foods on longevity.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

May 06, 2022
Dr. Ali Torkamani—Genomics and Aging
2321

Your genetics can uncover many things about you. They can influence how you look and behave, to name a few. But your genes are not deterministic; they don't tell your entire story.

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Ali Torkamani, Director of Genome Informatics at the Scripps Research Translational Institute. Tune in as Dr. Ali Torkamani discusses how genetics impact lifespan and healthspan, why genetics aren't deterministic, and how lifestyle factors promote a healthier, longer life.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Apr 20, 2022
Dr. Eran Segal—The Value of Personalized Nutrition
2442

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eran Segal, Faculty Member at The Weizmann Institute of Science in Israel. Tune in as Dr. Eran Segal discusses the value of personalized nutrition, how data contributes to our knowledge of personalized food responses, and the relationship between food and longevity.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Apr 06, 2022
Dr. Raul Mostoslavsky—SIRT 6 and the Hallmarks of Aging
3668

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Raul Mostoslavsky, the Laurel Schwartz Professor of Oncology at Harvard Medical School. 

Dr. Raul Mostoslavsky has studied sirtuin functions in cancer for many years and has identified a pathway responsible for tumor growth in 30% to 40% of pancreatic cancer patients and more recently identified metabolism as a heterogeneous feature of cancer. Dr. Raul Mostoslavsky discusses the role of sirtuins in aging and explains how the mechanisms that protect us from cancer may also preserve our longevity on a cellular level.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Mar 25, 2022
Dr. Steven Austad—A Unique Perspective to Aging Research
2805

In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Steven Austad, Professor and Protective Life Endowed Chair in Healthy Aging Research of the Department of Biology at the University of Alabama at Birmingham. Tune in as Dr. Steven Austad describes how his unique career path from lion tamer to aging researcher has influenced his perspective on the top questions in the field.  

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Mar 09, 2022
Dr. Nir Barzilai—Genetics and Lifestyle Factors of Centenarians
3457

Aging research is quickly evolving to understand how we can live healthier, longer lives. Scientists are looking to centenarians and their family members to reveal how their environment, lifestyle, and genetics contribute to their delayed aging.

In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Nir Barzilai,  Director of the Institute for Aging Research at the Albert Einstein College of Medicine. Tune in as Dr. Nir Barzilai describes how he pursued a career in aging, where the research stands on metformin and longevity, and the Longevity Genes Project, genome mapping 750 centenarians and their family members to understand the genetic component of aging.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Feb 22, 2022
Dr. Matt Kaeberlein—Novel Research on Longevity Agents in Domestic Dogs
3521

Recent studies highlight the role of specific longevity agents like rapamycin in slowing the aging process in animal models. Namely, scientists believe that rapamycin, proper nutrition, and caloric restriction may slow down the aging process in animal models and may be transferable to human health.

In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Matt Kaeberlein, Professor at the Department of Laboratory Medicine and Pathology at the University of Washington. Tune in as Dr. Matt Kaeberlein describes the longevity agent rapamycin and its impact on mTOR and the Dog Aging Project, which is investigating companion dogs as a model organism for aging.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Feb 08, 2022
Dr. Heidi Tissenbaum–Lessons From C. Elegans to Increase Healthspan
2789

In recent years, aging research has shifted its focus from lifespan to healthspan to understand the processes that define aging. Dr. Heidi Tissenbaum’s research investigates the fundamental pathways and genes that determine how we age.
 
In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Heidi Tissenbaum, professor at the University of Massachusetts Medical School. Tune in as Dr. Heidi Tissenbaum distinguishes between lifespan and healthspan, how she uses C. Elegans as a model organism for aging, and how added dietary sugars can interfere with longevity.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Jan 31, 2022
Dr. Haim Cohen — The Protective Role of SIRT6 on Aging and Longevity
2593

One topic that Longevity by Design guests can agree on is that sirtuin-6 (SIRT6) plays a protective role in aging and age-related conditions. Dr. Haim Cohen’s lab researches sirtuins, a class of enzymes involved in longevity and aging. He’s specifically interested in SIRT6 and its protective role in the aging process, as well as age-related conditions like cancer, insulin resistance, inflammation, and metabolic health.

In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Haim Cohen, Director of the National Metabolic Center for Excellence in Scientific Research in Human Diseases, and professor at Bar-Ilan University. Tune in as Dr. Haim Cohen takes a deep dive into SIRT6 and how his groundbreaking discovery about this enzyme can contribute to what we know about the aging process. 

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Jan 12, 2022
Dr. Andrew Huberman — How The Gut Microbiome, Sleep, and Sunlight Impact The Brain
3631

Inspired by the great unknowns of the brain, Dr. Andrew Huberman pursued neuroscience. From there, he realized that his passion also lay in the art of conveying scientific information in a way that scientists and non-scientists alike can understand. 

In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Andrew Huberman. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at the Stanford University School of Medicine and host of the Huberman Labs Podcast.

Tune in as Dr. Andrew Huberman takes a deep dive into how the gut microbiome, sleep, and sunlight impact the brain and how to hack your daily habits to live a healthier, longer life.

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast


Dec 08, 2021
Dr. Vera Gorbunova — Applying Lessons From Long-Living Animals to Combat Human Aging
2029

Did you know that there are species of whales that can live to be over 200 years old? Or that naked mole rats can live up to ten times longer than other mice? These facts and more led scientist Dr. Vera Gorbunova to investigate the mechanisms behind long-lived species and how these can be applied to what we know about aging in humans. 

In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Vera Gorbunova, Professor of Biology at the University of Rochester and co-director of the Rochester Aging Research Center. Tune in as Dr. Vera Gorbunova discusses commonalities between long-lived animals and how humans can apply these principles into their lives today. 

To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Nov 19, 2021
Dr. Brian Kennedy — How Simple Lifestyle Changes Can Slow Down the Aging Process
2427

We can’t rely on the magical elixir of life to stay forever young and healthy, but we can change certain lifestyle habits associated with premature aging. 

In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Brian Kennedy, Professor of Biochemistry and Physiology at the National University of Singapore, to discuss his approach to longevity and aging. 

Longevity is a complex matter, but Dr. Brian Kennedy explains its most vital details. Tune in to this episode to learn more about how food choices, supplements, exercise, and other lifestyle habits that we can control encourage longevity and prevent associated diseases. 

To learn more and download InsideTracker's InnerAge eBook, visit: insidetracker.com/podcast

Oct 30, 2021
Dr. William Evans – Why Muscle Mass is a Marker of Longevity
3188

Should the elderly engage in physical activity? How do nutrient needs change throughout the lifespan? Researchers and scientists worldwide strive to get revolutionary answers to top aging questions. Our guest is one of them. 

In this episode of the Longevity by Design podcast, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. William Evans, adjunct professor of Human Nutrition at the University of California, Berkeley. Dr. Evans was the first to describe sarcopenia, the age-related loss of muscle mass and strength. Additionally, Dr. William Evans’ research sheds light on the connection between sarcopenia and lower levels of biomarkers like testosterone, estrogen, growth hormone production, and increased insulin resistance.

Tune in to this episode, as Dr. William Evans discusses his research on exercise in older adults, how protein requirements change during the lifespan, and how this contributes to aging as a whole. 

To learn more and download InsideTracker's InnerAge eBook, visit: insidetracker.com/podcast

Sep 30, 2021
Dr. David Sinclair – A World-Renowned Scientist's View on Longevity and Health
2281

Dr. David Sinclair is a world-renowned scientist with a rich background in genetics and longevity research. Dr. David Sinclair, Ph.D., A.O. is a geneticist at Harvard Medical School and a Co-founder and Co-chief editor of the journal Aging. He's an inventor on 35 patents and has received more than 35 awards and honors. We're proud to have him on our team as the Chairman of the InsideTracker Scientific Advisory Board. 

Is aging a disease or a natural process? How can we impact aging on a cellular level? What daily habits can you implement to improve your lifespan? How does intermittent fasting impact cell function and longevity? 

In this episode of the Longevity by Design podcast, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. David Sinclair to discuss his aging research, top tips for longevity, and interestingly, what it’s like to work in his lab.

For an exclusive offer, visit: https://info.insidetracker.com/sinclair 

Aug 18, 2021
Why Lifestyle is the Key to Longevity With Dr. David Katz
3609

The Founding Director of Yale University's Yale-Griffin prevention research center, Dr. David Katz, joins our hosts, Dr. Gil Blender and Ashley Reaver, to discuss the importance of a healthy lifestyle in increasing longevity.

  • We need to prioritize prevention in healthcare. A more preventative approach to health could help postpone and even prevent severe conditions from developing. 
  • There are many benefits of adopting better lifestyle habits. According to Dr. Katz, lifestyle is the key to vitality and longevity. 
  • Poor diet choices lead to weight gain and chronic disease development such as diabetes and obesity. It's essential to eat real, not processed food and drink water regularly.

Being healthy is not just about consuming vegetables and avoiding processed foods. It's a lifestyle. Our podcast guest says that lifestyle is a medicine that prevents chronic diseases from developing. You are what you eat, what you do, and what you drink. 

Dr. David Katz is the Founding Director of Yale University's Yale-Griffin prevention research center, a CDC-funded clinical research lab he ran for 21 years. He's also the Founder and currently the Chief Executive Officer of Diet ID, an API intended to disrupt current processes for dietary intake, goal setting, and nutritional coaching. He's joined the advisory board of InsideTracker to help people optimize their bodies using science and technology.

In this episode of the Longevity by Design podcast, Dr. Katz discusses the endless benefits of healthy living. If you want to hear why diet quality is critical and what we can do to promote better eating habits, tune in to the latest episode of the podcast to find out more.

To learn more and download InsideTracker's InnerAge eBook, visit: https://info.insidetracker.com/podcast


May 11, 2021
What Aging Research Tells Us About Longevity with Danica Chen
1774

How and why do we age? Is aging reversible? These are some of the most critical questions in biology. Fortunately for us, researchers and scientists across the world strive to get some revolutionary answers. Our guest is one of them.

Danica Chen is a Professor of Metabolic Biology, Nutritional Sciences & Toxicology at the University of California at Berkeley. Even though she originally intended to study international accounting, life had other plans, so she switched her major and went in another direction. Now, she's a member of Berkeley Stem Cell Center and a member of QB3 Consortium in Lifespan Extension, conducting research studies that aim to understand aging-associated conditions.

Danica says the future of aging research is bright. "Using the knowledge we have learned from aging research and applying it to improve human health is what the aging field is trying to accomplish." In this episode of the Longevity by Design podcast, our hosts and Danica discuss the challenges in aging research, STEM cells' role in aging, and why the elderly are more prone to COVID. Tune in to the latest episode to find out more.

To learn more and download InsideTracker's InnerAge eBook, visit: https://info.insidetracker.com/podcast

Apr 15, 2021