Science is restless. It's always seeking, always exploring, always striving to answer new questions and build off the knowledge it has already gained. In HIV, we've spent decades refining our understanding of the virus and its complex web of intersections with our bodies and our societies. Yet we constantly strive to learn more, and to create ever-more-effective means by which we can prevent HIV transmission, treat HIV infection, and improve the length and quality of the lives of people affected by this 40-year pandemic. In this monthly podcast, HIV and the Future will zoom in on one area within HIV-related science to highlight innovative projects and explain the bigger questions and issues they seek to resolve. Our explorations will include current and upcoming pilot studies or demonstration programs, as well as unsung but important new projects that seek to tackle big issues around HIV prevention, treatment, and care. We will interview the scientists and clinicians involved in this innovative work, as well as experts in relevant subfields who can speak to the broader implications of that work for the future of HIV and health care.