Can mathematics handle things that are essentially the same without being exactly equal? Category theorist Eugenia Cheng and host Steven Strogatz discuss the power and pleasures of abstraction.

Making living cells blink fluorescently like party lights may sound frivolous. But the demonstration that it’s possible could be a step toward someday programming our body’s immune cells to attack cancers more effectively and safely. That’s the promise of synthetic biology. While molecular biologists strip cells down to their component genes and molecules to see how they work, synthetic biologists tinker with cells to get them to perform new feats — and discover new secrets about how life works in the process. In this episode, Steven Strogatz talks with Michael Elowitz, a professor of biology and bioengineering at the California Institute of Technology and a Howard Hughes Medical Institute Investigator.

“The Joy of Why” is a podcast about curiosity and the pursuit of knowledge from Quanta Magazine. The acclaimed mathematician and author Steven Strogatz interviews leading researchers about the great scientific and mathematical questions of our time.

As The Joy of Why podcast returns for a second season, producer Polly Stryker and host Steven Strogatz invite listeners to join them and their brilliant new guests on another voyage of discovery.

Dreams are so personal, subjective and fleeting, they might seem impossible to study directly and with scientific objectivity. But in recent decades, laboratories around the world have developed sophisticated techniques for getting into the minds of people while they are dreaming. In the process, they are learning more about why we need these strange nightly experiences and how our brains generate them. In this episode, Steven Strogatz speaks with sleep researcher Antonio Zadra about how new experimental methods have changed our understanding of dreams.

“The Joy of Why” is a podcast from Quanta Magazine, an editorially independent publication supported by the Simons Foundation. Funding decisions by the Simons Foundation have no influence on the selection of topics, guests, or other editorial decisions in this podcast or in Quanta Magazine. “The Joy of Why” is produced by Susan Valot and Polly Stryker. Our editors are John Rennie and Thomas Lin, with support by Matt Carlstrom, Annie Melchor and Leila Sloman. Our theme music was composed by Richie Johnson. Our logo is by Jackie King, and artwork for the episodes is by Michael Driver and Samuel Velasco. Our host is Steven Strogatz. If you have any questions or comments for us, please email us at quanta@simonsfoundation.org.

Quantum field theory may be the most successful scientific theory of all time, predicting  experimental results with stunning accuracy and advancing the study of higher dimensional mathematics. Yet, there’s also reason to believe that it is missing something. Steven Strogatz speaks with David Tong, a theoretical physicist at the University of Cambridge, to explore the open questions of this enigmatic theory.

“The Joy of Why” is a podcast from Quanta Magazine, an editorially independent publication supported by the Simons Foundation. Funding decisions by the Simons Foundation have no influence on the selection of topics, guests, or other editorial decisions in this podcast or in Quanta Magazine. “The Joy of Why” is produced by Susan Valot and Polly Stryker. Our editors are John Rennie and Thomas Lin, with support by Matt Carlstrom, Annie Melchor and Leila Sloman. Our theme music was composed by Richie Johnson. Our logo is by Jackie King, and artwork for the episodes is by Michael Driver and Samuel Velasco. Our host is Steven Strogatz. If you have any questions or comments for us, please email us at quanta@simonsfoundation.org.

Everybody gets older, but not everyone ages in the same way. For many people, late life includes a deterioration of health brought on by age-related disease. But that’s not true for everyone, and around the world, women typically live longer than men. Why is that? In this episode, Steven Strogatz speaks with Judith Campisi and Dena Dubal, two biomedical researchers who study the causes and outcomes of aging to understand how it works — and what scientists know about postponing or even reversing the aging process.

“The Joy of Why” is a podcast from Quanta Magazine, an editorially independent publication supported by the Simons Foundation. Funding decisions by the Simons Foundation have no influence on the selection of topics, guests, or other editorial decisions in this podcast or in Quanta Magazine. “The Joy of Why” is produced by Susan Valot and Polly Stryker. Our editors are John Rennie and Thomas Lin, with support by Matt Carlstrom, Annie Melchor and Leila Sloman. Our theme music was composed by Richie Johnson. Our logo is by Jackie King, and artwork for the episodes is by Michael Driver and Samuel Velasco. Our host is Steven Strogatz. If you have any questions or comments for us, please email us at quanta@simonsfoundation.org. 

How can anyone say something with certainty about infinity? What can we really know about the mysterious prime numbers without knowing all of them? Just as scientists need data to assess their hypotheses, mathematicians need evidence to prove or disprove conjectures. But what counts as evidence in the intangible realm of number theory? In this episode, Steven Strogatz speaks with Melanie Matchett Wood, a professor of mathematics at Harvard University, to learn how probability and randomness can help establish evidence for the airtight arguments demanded of mathematicians.“The Joy of Why” is a podcast from Quanta Magazine, an editorially independent publication supported by the Simons Foundation. Funding decisions by the Simons Foundation have no influence on the selection of topics, guests, or other editorial decisions in this podcast or in Quanta Magazine. “The Joy of Why” is produced by Susan Valot and Polly Stryker. Our editors are John Rennie and Thomas Lin, with support by Matt Carlstrom, Annie Melchor and Leila Sloman. Our theme music was composed by Richie Johnson. Our logo is by Jackie King, and artwork for the episodes is by Michael Driver and Samuel Velasco. Our host is Steven Strogatz. If you have any questions or comments for us, please email us at quanta@simonsfoundation.org.

How do you teach mathematics to an artificial intelligence? AI has already bested humans at various problem-solving tasks, including games like chess and Go. But before any task can be tackled by a machine, it must be reinterpreted as  directions in language that computers can understand. For the last few years, researchers and amateurs all over the world have worked together to translate the essential axioms of mathematics into a programming language called Lean. Armed with this knowledge, theorem-proving programs that understand Lean have begun helping some of the world’s greatest mathematicians verify their work. Steven Strogatz speaks with Kevin Buzzard, professor of pure mathematics at Imperial College London, about the effort to “teach” math to Lean — and how projects like this one could shape the future of math.

“The Joy of Why” is a podcast from Quanta Magazine, an editorially independent publication supported by the Simons Foundation. Funding decisions by the Simons Foundation have no influence on the selection of topics, guests, or other editorial decisions in this podcast or in Quanta Magazine. “The Joy of Why” is produced by Susan Valot and Polly Stryker. Our editors are John Rennie and Thomas Lin, with support by Matt Carlstrom, Annie Melchor and Leila Sloman. Our theme music was composed by Richie Johnson. Our logo is by Jackie King, and artwork for the episodes is by Michael Driver and Samuel Velasco. Our host is Steven Strogatz. If you have any questions or comments for us, please email us at quanta@simonsfoundation.org.

Scientists don’t really agree on a definition for life. We may recognize life instinctively most of the time, but any time we try to nail it down with set criteria, some stubborn counterexample spoils the effort. Still, can we really search for life on other worlds, or understand the earliest stages of life on this planet, if we don’t know what to look for? On this episode, Steven Strogatz speaks with Robert Hazen, a mineralogist, astrobiologist and senior staff scientist at the Carnegie Institution’s Earth and Planets Laboratory, along with Sheref Mansy, professor of chemistry at the University of Alberta, to learn more about how new taxonomies and a “cellular Turing test” might help us answer this essential question.

“The Joy of Why” is a podcast from Quanta Magazine, an editorially independent publication supported by the Simons Foundation. Funding decisions by the Simons Foundation have no influence on the selection of topics, guests, or other editorial decisions in this podcast or in Quanta Magazine. “The Joy of Why” is produced by Susan Valot and Polly Stryker. Our editors are John Rennie and Thomas Lin, with support by Matt Carlstrom, Annie Melchor and Leila Sloman. Our theme music was composed by Richie Johnson. Our logo is by Jackie King, and artwork for the episodes is by Michael Driver and Samuel Velasco. Our host is Steven Strogatz. If you have any questions or comments for us, please email us at quanta@simonsfoundation.org. 

How did life begin on Earth? It’s one of the greatest and most ancient mysteries in all of science — and the clues to solving it are all around us. Biologists have sometimes imagined evolutionary history as a recorded “tape of life” that might turn out differently if it were replayed again and again. In this episode, Steven Strogatz speaks with two researchers inspecting different parts of the tape. First, hear from the Nobel Prize-winning biologist Jack Szostak, who explores how a boiling pool laced with cyanide could have given rise to essential life elements like RNA and DNA. Then hear from Betül Kaçar, a paleogeneticist and astrobiologist who resurrects ancient genes to learn how they helped evolve the processes essential to modern life.

“The Joy of Why” is a podcast from Quanta Magazine, an editorially independent publication supported by the Simons Foundation. Funding decisions by the Simons Foundation have no influence on the selection of topics, guests, or other editorial decisions in this podcast or in Quanta Magazine. “The Joy of Why” is produced by Susan Valot and Polly Stryker. Our editors are John Rennie and Thomas Lin, with support by Matt Carlstrom, Annie Melchor and Leila Sloman. Our theme music was composed by Richie Johnson. Our logo is by Jackie King, and artwork for the episodes is by Michael Driver and Samuel Velasco. Our host is Steven Strogatz. If you have any questions or comments for us, please email us at quanta@simonsfoundation.org. 

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