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Episodes: 1953

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Audio versions of bioRxiv and medRxiv paper abstracts

Episode Date
AAontology: An ontology of amino acid scales for interpretable machine learning
Aug 05, 2023
A dose-response based model for statistical analysis of chemical genetic interactions in CRISPRi libraries
Aug 05, 2023
PxBLAT: An Ergonomic and Efficient Python Binding Library for BLAT
Aug 05, 2023
CellGO: A novel deep learning-based framework and webserver for cell type-specific gene function interpretation
Aug 05, 2023
Chrombus-XMBD: A Graph Generative Model Predicting 3D-Genome, ab initio from Chromatin Features
Aug 05, 2023
Bioinformatics and next generation data analysis reveals the potential role of inflammation in sepsis and its associated complications
Aug 05, 2023
Compound models and Pearson residuals for normalization of single-cell RNA-seq data without UMIs
Aug 05, 2023
Multi-representation DeepInsight: an improvement on tabular data analysis
Aug 05, 2023
Can a Sparse 29 x 29 Pixel Chaos Game Representation Predict Protein Binding Sites using Fine-Tuned State-of-the Art Deep Learning Semantic Segmentation Models?
Aug 04, 2023
Single-linkage molecular clustering of viral pathogens
Aug 04, 2023
memerna: Sparse RNA Folding Including Coaxial Stacking
Aug 04, 2023
Interface-guided phenotyping of coding variants in the transcription factor RUNX1 with SEUSS
Aug 04, 2023
Comparing full variation profile analysis with the conventional consensus method in SARS-CoV-2 phylogeny
Aug 04, 2023
Neo-epitope identification by weakly-supervised peptide-TCR binding prediction
Aug 03, 2023
A versatile framework for drug-target interaction prediction by considering domain specific features
Aug 03, 2023
An AI-assisted Investigation of Tumor-Associated Macrophages and their Polarization in Colorectal Cancer
Aug 03, 2023
FiTMuSiC: Leveraging structural and (co)evolutionary data for protein fitness prediction
Aug 03, 2023
From Proteins to Ligands: Decoding Deep Learning Methods for Binding Affinity Prediction
Aug 03, 2023
Continuous lifelong learning for modeling of gene regulation from single cell multiome data by leveraging atlas-scale external data
Aug 03, 2023
SAMPLER: Empirical distribution representations for rapid analysis of whole slide tissue images
Aug 03, 2023
PoMeLo: a systematic computational approach to predicting metabolic loss in pathogen genomes
Aug 03, 2023
Non-sequential alignment of binding sites for fast peptide screening
Aug 03, 2023
The importance of DNA sequence for nucleosome positioning in the process of transcriptional regulation
Aug 03, 2023
Unraveling the Pathogenesis of Idiopathic Pulmonary Fibrosis Complicated with Type 2 Diabetes through Microarray Data Analysis
Aug 02, 2023
MousiPLIER: A Mouse Pathway-Level Information Extractor Model
Aug 02, 2023
NetActivity enhances transcriptional signals by combining gene expression into robust gene set activity scores through interpretable autoencoders
Aug 02, 2023
SR2: Sparse Representation Learning for Scalable Single-cell RNA Sequencing Data Analysis
Aug 02, 2023
ProjectSVR: Mapping single-cell RNA-seq data to reference atlases by supported vector regression
Aug 02, 2023
Machine Learning Gene Signature to Metastatic ccRCC based on ceRNA Network
Aug 02, 2023
Unveiling a Potential Prognostic Biomarker in KRAS-Mutant Lung Adenocarcinoma Using Weighted Gene Co-Expression Network Analysis
Aug 02, 2023
A systematic comparison of computational methods for expression forecasting
Jul 31, 2023
NetVA: An R Package for Network Vulnerability and Influence Analysis
Jul 31, 2023
Model-based compound hypothesis testing for snATAC-seq data with PACS
Jul 31, 2023
disperseNN2: a neural network for estimating dispersal distance from georeferenced polymorphism data
Jul 31, 2023
A diversified, widespread microbial gene cluster encodes homologs of methyltransferases involved in methanogenesis.
Jul 31, 2023
The Role of C-to-U RNA Editing in Human Biodiversity
Jul 31, 2023
ISMI-VAE: A Deep Learning Model for Classifying Disease Cells Using Gene Expression and SNV Data
Jul 31, 2023
Picky with peakpicking: assessing chromatographic peak quality with simple metrics in metabolomics
Jul 30, 2023
Unraveling cell differentiation mechanisms through topological exploration of single-cell developmental trajectories
Jul 30, 2023
Transfer learning to leverage larger datasets for improved prediction of protein stability changes
Jul 30, 2023
Extended Similarity Methods for Efficient Data Mining in Imaging Mass Spectrometry
Jul 30, 2023
An Optimized Pipeline for Detection of Salmonella Sequences in Shotgun Metagenomics Datasets
Jul 30, 2023
einprot: flexible, easy-to-use, reproducible workflows for statistical analysis of quantitative proteomics data
Jul 30, 2023
Clade-wise alignment integration improves co-evolutionary signals for protein-protein interaction prediction
Jul 30, 2023
Context-Dependent Design of Induced-fit Enzymes using Deep Learning Generates Well Expressed, Thermally Stable and Active Enzymes
Jul 29, 2023
MethyLasso: a segmentation approach to analyze DNA methylation patterns and identify differentially methylation regions from whole-genome datasets
Jul 29, 2023
GAPiM: Discovering Genetic Variations on a Real Processing-in-Memory System
Jul 29, 2023
Directly selecting differentially expressed genes for single-cell clustering analyses
Jul 29, 2023
Deep Batch Active Learning for Drug Discovery
Jul 29, 2023
Assessing the basal gene expression of cancer cell lines for in vitro transcriptomic toxicology screening
Jul 29, 2023
Mcadet: a feature selection method for fine-resolution single-cell RNA-seq data based on multiple correspondence analysis and community detection
Jul 29, 2023
getphylo: rapid and automatic generation of multi-locus phylogentic trees from genbank files
Jul 29, 2023
Time-Informed Dimensionality Reduction for Longitudinal Microbiome Studies
Jul 29, 2023
Sensitive remote homology search by local alignment of small positional embeddings from protein language models
Jul 29, 2023
A comprehensive experimental comparison between federated and centralized learning
Jul 29, 2023
ProteoMixture: A Cell Type Deconvolution Tool for Bulk Tissue Proteomics Data
Jul 29, 2023
Modeling Kinetics of RNA RNA Interactions on Direct Paths
Jul 29, 2023
mAFiA: Detecting m6A at single-molecular resolution via direct-RNA sequencing
Jul 29, 2023
Look4LTRs: A Long terminal repeat retrotransposon detection tool capable of cross species studies and discovering recently nested repeats
Jul 29, 2023
Star allele search: a pharmacogenetic annotation database and user-friendly search tool of publicly available 1000 Genomes Project biospecimens
Jul 29, 2023
Gradient-based implementation of linear model outperforms deep learning models
Jul 29, 2023
Analyzing interaction of rhodacyanine inhibitor MKT-077 with Plasmodium falciparum HSP70 nucleotide binding domains
Jul 29, 2023
LipidSIM: inferring mechanistic lipid biosynthesis perturbations from lipidomics with a flexible, low-parameter, systematic Markov Modeling framework
Jul 28, 2023
ChromaFold predicts the 3D contact map from single-cell chromatin accessibility
Jul 28, 2023
AnglesRefine: refinement of 3D protein structures using Transformer based on torsion angles
Jul 28, 2023
Quantification of circulating tumor DNA using deep learning
Jul 28, 2023
cloudrnaSPAdes: Isoform assembly using bulk barcoded RNA sequencing data
Jul 27, 2023
Challenges in identifying mRNA transcript starts and ends from long-read sequencing data
Jul 27, 2023
Self-targeting spacers reveal new functions of CRISPR systems
Jul 27, 2023
Predicting Relative Populations of ProteinConformations without a Physics Engine UsingAlphaFold2
Jul 27, 2023
GRouNdGAN: GRN-guided simulation of single-cell RNA-seq data using causal generative adversarial networks
Jul 27, 2023
CellSNAP: A fast, accurate algorithm for 3D cell segmentation in quantitative phase imaging
Jul 26, 2023
Mining drug-target interactions from biomedical literature using chemical and gene descriptions based ensemble transformer model
Jul 26, 2023
Data-driven probabilistic definition of the low energy conformational states of protein residues
Jul 26, 2023
ursaPGx: a new R package to annotate pharmacogenetic star alleles using phased whole genome sequencing data
Jul 26, 2023
Structural Coverage of the Human Interactome
Jul 26, 2023
Discovering genetic biomarkers for targeted cancer therapeutics with eXplainable AI
Jul 26, 2023
scViralQuant: A tool for efficient alignment and quantification of viral reads from 10x single cell sequencing data sets
Jul 26, 2023
Benchmarking DNA Isolation Methods for Marine Metagenomics Studies
Jul 26, 2023
A Versatile Tool for Precise Variant Calling in Mycobacterium tuberculosis Genetic Polymorphisms
Jul 26, 2023
HLA-DR4Pred2: an improved method for predicting HLA-DRB1*04:01 binders
Jul 26, 2023
EPINEST, an agent-based model to simulate epidemic dynamics in large-scale poultry production and distribution networks
Jul 26, 2023
AntiBP3: A hybrid method for predicting antibacterial peptides against gram-positive/negative/variable bacteria
Jul 26, 2023
Immune Profiling among Colorectal Cancer Subtypes using Dependent Mixture Models
Jul 26, 2023
Differentiable Search of Evolutionary Trees from Leaves
Jul 25, 2023
Deep learning-based cell profiling based on neuronal morphology
Jul 25, 2023
Investigation of latent representation of toxicopathological images extracted by CNN model for understanding compound properties in vivo
Jul 25, 2023
ProstT5: Bilingual Language Model for Protein Sequence and Structure
Jul 25, 2023
hadge: a comprehensive pipeline for donor deconvolution in single cell
Jul 25, 2023
Highly accurate estimation of cell type abundance in bulk tissues based on single-cell reference and domain adaptive matching
Jul 25, 2023
Collaborative network analysis for the interpretation of transcriptomics data in rare diseases, an application to Huntington's disease
Jul 25, 2023
ClusterDE: a post-clustering differential expression (DE) method robust to false-positive inflation caused by double dipping
Jul 25, 2023
Identification of a botulinum neurotoxin-like gene cluster in Bacillus toyonensis
Jul 25, 2023
AlphaFold2 models of the active form of all 437 catalytically-competent typical human kinase domains
Jul 25, 2023
Meta-colored compacted de Bruijn graphs: overview and challenges
Jul 25, 2023
Detection of viral infection in cell lines using ViralCellDetector
Jul 25, 2023
Exploring NCATS In-House Biomedical Data for Evidence-based Drug Repurposing
Jul 25, 2023
Prominent contributions of selective neuronal subtypes to pediatric drug-resistant focal dysplasia
Jul 25, 2023
ScopeViewer: A Browser-Based Solution for Visualizing Spatial Transcriptomics Data
Jul 25, 2023
A Strategy for Differential Abundance Analysis of Sparse Microbiome Data with Group-wise Structured Zeros
Jul 25, 2023
ChromatinHD connects single-cell DNA accessibility and conformation to gene expression through scale-adaptive machine learning
Jul 25, 2023
Looking at the Full Picture: Utilizing Topic Modeling to Determine Disease-Associated Microbiome Communities
Jul 25, 2023
Computational Engineering of a Therapeutic Antibody to Inhibit Multiple Mutants of HER2 Without Compromising Inhibition of the Canonical HER2
Jul 25, 2023
CRUX, a platform for visualising, exploring and analysing cancer genome cohort data
Jul 25, 2023
Using graph-based model to identify cell specific synthetic lethal effects
Jul 25, 2023
Identification of Low-Complexity Domains by Compositional Signatures Reveals Class-Specific Frequencies and Functions Across Reference Proteomes
Jul 25, 2023
MLOsMetaDB, a meta-database to centralize the information on Liquid-liquid phase separation proteins and Membraneless organelles.
Jul 25, 2023
Revisiting structural organization of proteins at high temperature from network perspective
Jul 25, 2023
Unraveling the Potential of Epicatechin Gallate in Targeting Aberrant Cardiac Ca2+ Signaling Protein
Jul 25, 2023
Autoencoder-transformed transcriptome improves genotype-phenotype association studies
Jul 25, 2023
AmpliDiff: An Optimized Amplicon Sequencing Approach to Estimating Lineage Abundances in Viral Metagenomes
Jul 24, 2023
3 Directional Inception-ResUNet: deep spatial feature learning for multichannel singing voice separation with distortion
Jul 24, 2023
Addressing persistent challenges in digital image analysis of cancerous tissues
Jul 24, 2023
Predicting gene expression changes upon epigenomic drug treatment
Jul 23, 2023
Mendelian disease comorbidity as a resource for novel therapeutic targets
Jul 23, 2023
Charting cellular differentiation trajectories with Ricci flow
Jul 23, 2023
Taxor: Fast and space-efficient taxonomic classification of long reads with hierarchicalinterleaved XOR filters
Jul 22, 2023
A Motion Transformer for Single Particle Tracking in Fluorescence Microscopy Images
Jul 22, 2023
FocA: A deep learning tool for reliable, near-real-time imaging focus analysis in automated cell assay pipelines
Jul 22, 2023
Identification of five characteristic ferroptosis-related genes as novel biomarkers for ischemic stroke using bioinformatic and machine learning strategies
Jul 22, 2023
Voyager: exploratory single-cell genomics data analysis with geospatial statistics
Jul 22, 2023
PseudoCell: A collaborative network for in silico prediction of regulatory pathways
Jul 22, 2023
BuDDI: Bulk Deconvolution with Domain Invariance to predict cell-type-specific perturbations from bulk
Jul 22, 2023
Cellular proliferation biases clonal lineage tracing and trajectory inference
Jul 22, 2023
Efficient protein structure archiving using ProteStAr
Jul 22, 2023
Identifying Clusters in Graph Representations of Genomes
Jul 22, 2023
DIMPLE: AN R PACKAGE TO QUANTIFY, VISUALIZE, AND MODEL SPATIAL CELLULAR INTERACTIONS FROM MULTIPLEX IMAGING WITH DISTANCE MATRICES
Jul 22, 2023
PANDORA v2.0: Benchmarking peptide-MHC II models and software improvements
Jul 22, 2023
Predicting Gene Spatial Expression and Cancer Prognosis: An Integrated Graph and Image Deep Learning Approach Based on HE Slides
Jul 21, 2023
In-silico identification, characterization, and expression analysis of RNA recognition motif (RRM) containing RNA binding proteins in Aedes aegypti
Jul 21, 2023
Hidden Markov Models based search in combination with structural bioinformatics pipeline leads to the identification of DAF-12 distant orthologous in Meloidogyne incognita
Jul 21, 2023
EPIGENOMIC VARIABILITY AND TRANSCRIPTOMICS AS A NOVEL MULTIOMIC COMPLEMENTARY APPROACH FOR PERSONALIZED NUTRITION IN COLORECTAL CANCER PATIENTS
Jul 20, 2023
Unified fate mapping in multiview single-cell data
Jul 20, 2023
Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in TimsTOF
Jul 19, 2023
Recurrent composite markers of cell types and states
Jul 19, 2023
Estimating error rates for single molecule protein sequencing experiments
Jul 19, 2023
Predicting cell morphological responses to perturbations using generative modeling
Jul 19, 2023
Solving the Pervasive Problem of Protocol Non-Compliance in MRI using an Open-Source tool mrQA
Jul 19, 2023
Molecular Surface Descriptors to Predict Antibody Developability
Jul 19, 2023
PhageScanner, a flexible machine learning pipeline for automated bacteriophage genomic and metagenomic feature annotation
Jul 19, 2023
mEthAE: an Explainable AutoEncoder for methylation data
Jul 19, 2023
Scalable querying of human cell atlases via a foundational model reveals commonalities across fibrosis-associated macrophages
Jul 19, 2023
Contextualizing protein representations using deep learning on protein networks and single-cell data
Jul 19, 2023
Zero-Shot Transfer of Protein Sequence Likelihood Models to Thermostability Prediction
Jul 19, 2023
Microenvironment of metastatic site reveals key predictors of PD-1 blockade response in renal cell carcinoma
Jul 19, 2023
A Template for Translational Bioinformatics: Facilitating Multimodal Data Analyses in Preclinical Models of Neurological Injury
Jul 19, 2023
Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discovery
Jul 19, 2023
Random, de novo and conserved proteins: How structure and disorder predictors perform differently
Jul 19, 2023
A novel machine learning algorithm picks proteome signature to specifically identify cancer exosomes
Jul 19, 2023
TULIP - a Transformer based Unsupervised Language model for Interacting Peptides and T-cell receptors that generalizes to unseen epitopes
Jul 19, 2023
Using random forests to uncover the predictive power of distance-varying cell interactions in tumor microenvironments
Jul 19, 2023
High-throughput complement component 4 genomic sequence analysis with C4Investigator
Jul 19, 2023
Profiling the Expression of Transportome Genes in cancer: A systematic approach
Jul 19, 2023
Understanding the structural basis for differential binding of lapachol with PfHSP70s
Jul 19, 2023
cycle_finder: de novo analysis of tandem and interspersed repeats based on cycle-finding
Jul 19, 2023
Benchmarking and optimization of cell-free DNA deconvolution
Jul 19, 2023
Benchmarking software tools for trimming adapters and merging next-generation sequencing data for ancient DNA
Jul 19, 2023
A Systematic Identification of RBPs Driving Aberrant Splicing in Cancer
Jul 18, 2023
Proteasomal cleavage prediction: state-of-the-art and future directions
Jul 18, 2023
Reliable interpretability of biology-inspired deep neural networks
Jul 18, 2023
Nucleus basalis of Meynert degeneration signals earliest stage of Alzheimer's disease progression
Jul 18, 2023
rvTWAS: identifying gene-trait association using sequences by utilizing transcriptome-directed feature selection
Jul 18, 2023
Brightest path tracing: A Python package to trace the brightest path in 2D and 3D images.
Jul 18, 2023
Characterizing dysregulations via cell-cell communications in Alzheimer's brains using single-cell transcriptomes
Jul 18, 2023
A data standard for the reuse and reproducibility of any stable isotope probing-derived nucleic acid sequence (MISIP)
Jul 17, 2023
MosaiCatcher v2: a single-cell structural variations detection and analysis reference framework based on Strand-seq
Jul 17, 2023
Metabolic Interactive Nodular Network for Omics (MINNO): Refining and investigating metabolic networks based on empirical metabolomics data
Jul 17, 2023
Host species and geography impact bee-associated RNA virus communities with evidence for isolation-by-distance in viral populations
Jul 17, 2023
XA4C: eXplainable representation learning via Autoencoders revealing Critical genes
Jul 17, 2023
Apis mellifera filamentous virus from a honey bee gut microbiome survey in Hungary
Jul 17, 2023
DeepDynaForecast: Phylogenetic-informed graph deep learning for epidemic transmission dynamic prediction
Jul 17, 2023
Contextual protein encodings from equivariant graph transformers
Jul 17, 2023
sNucConv: A bulk RNA-seq deconvolution method trained on single-nucleus RNA-seq data to estimate cell-type composition of human subcutaneous and visceral adipose tissues
Jul 17, 2023
Introducing PandaNovo for practical large-scale de novo peptide sequencing
Jul 16, 2023
The Patent and Literature Antibody Database (PLAbDab): an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures
Jul 16, 2023
Synergizing Geometric Deep Learning and Data-Centric Methods for Improved Protein Structural Alignment
Jul 16, 2023
tfboot: Bootstrapping and statistical analysis for transcription factor binding site-disrupting variants in gene sets
Jul 16, 2023
RNA Strain-Match: A tool for matching single-nucleus, single-cell, or bulk RNA-sequencing alignment data to its corresponding genotype
Jul 16, 2023
Precise Nanopore Signal Modeling Improves Unsupervised Single-Molecule Methylation Detection
Jul 15, 2023
Beam search decoder for enhancing sequence decoding speed in single-molecule peptide sequencing data
Jul 15, 2023
FLAG: Find, Label Annotate Genomes, a fully automated tool for genome gene structural and functional annotation of highly fragmented non-model species
Jul 15, 2023
TriTan: An efficient triple non-negative matrix factorisation method for integrative analysis of single-cell multiomics data
Jul 15, 2023
Integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell types
Jul 15, 2023
Accurately identifying nucleic-acid-binding sites through geometric graph learning on language model predicted structures
Jul 15, 2023
BERLIN: Basic Explorer for single-cell RNAseq analysis and cell Lineage Determination.
Jul 15, 2023
Predicting Disease-gene Associations through Self-supervised Mutual Infomax Graph Convolution Network
Jul 15, 2023
ChatGPT-Enhanced ROC Analysis (CERA): A Shiny Web Tool for Finding Optimal Cutoff in Biomarker Analysis
Jul 15, 2023
DeepETPicker: Fast and accurate 3D particle picking for cryo-electron tomography using weakly supervised deep learning
Jul 14, 2023
TFvelo: gene regulation inspired RNA velocity estimation
Jul 14, 2023
EnrichMiner: a biologist-oriented web server for mining biological insights from functional enrichment analysis
Jul 14, 2023
ScreenDMT reveals linoleic acid diols replicably associate with BMI and stimulate adipocyte calcium fluxes
Jul 14, 2023
Functional profiling of the sequence stockpile: a review and assessment of in silico prediction tools
Jul 14, 2023
A Conserved Electrostatic Membrane-Binding Surface in Synaptotagmin-Like Proteins Revealed Using Molecular Phylogenetic Analysis and Homology Modeling
Jul 13, 2023
AI2BMD: efficient characterization of protein dynamics with ab initio accuracy
Jul 13, 2023
Prediction of protein-RNA interactions from single-cell transcriptomic data
Jul 13, 2023
Integration of variant annotations using deep set networks boosts rare variant association genetics
Jul 13, 2023
reanalyzerGSE: tackling the everlasting lack of reproducibility and reanalyses in transcriptomics
Jul 13, 2023
Characterising neutrophil subtypes in cancer using human and murine single-cell RNA sequencing datasets
Jul 13, 2023
Peptriever: A Bi-Encoder approach for large-scale protein-peptide binding search
Jul 13, 2023
Identifying Protein Conformational States in the PDB and Comparison to AlphaFold2 Predictions
Jul 13, 2023
Ecological network inference is not consistent across sales or approaches
Jul 13, 2023
RNAGEN: A generative adversarial network-based model to generate synthetic RNA sequences to target proteins
Jul 12, 2023
fastlin: an ultra-fast program for Mycobacterium tuberculosis complex lineage typing
Jul 12, 2023
Salmonella enterica serovar Typhimurium ST313 sublineage 2.2 has emerged in Malawi with a characteristic gene expression signature and a fitness advantage
Jul 12, 2023
Hyperparameter optimisation in differential evolution using Summed Local Difference Strings, a rugged but easily calculated landscape for combinatorial search problems
Jul 12, 2023
The Landscape of Maize-Associated Bacteria and Fungi Across the United States
Jul 12, 2023
Tutorial: guidelines for manual cell type annotation of single-cell multi-omics datasets using interactive software
Jul 12, 2023
DNA Storage Designer: A practical and holistic design platform for storing digital information in DNA sequence
Jul 12, 2023
UNI-RNA: UNIVERSAL PRE-TRAINED MODELS REVOLUTIONIZE RNA RESEARCH
Jul 12, 2023
Exploiting protein language models for the precise classification of ion channels and ion transporters
Jul 12, 2023
Distinguishing word identity and sequence context in DNA language models
Jul 12, 2023
PlantConnectome: knowledge networks encompassing greater than 100,000 plant article abstracts
Jul 12, 2023
An interpretable deep learning framework for genome-informed precision oncology
Jul 12, 2023
Simulations of sequence evolution: how (un)realistic they really are and why
Jul 12, 2023
In-Silico analysis of Human Insulin Gene for Mirror repeat sequences
Jul 11, 2023
Robust Phylogenetic Tree-based Microbiome Association Test using Repeatedly Measured Data for Composition Bias
Jul 11, 2023
Metastatic prognostic ability of lung cancer stromal cells from a single-cell RNA-seq perspective
Jul 11, 2023
Improving genome-scale metabolic models of incomplete genomes with deep learning
Jul 11, 2023
The Impact of AI-Based Modeling on the Accuracy of Protein Assembly Prediction: Insights from CASP15
Jul 11, 2023
An error correction strategy for image reconstruction by DNA sequencing microscopy
Jul 11, 2023
ESQmodel: biologically informed evaluation of 2-D cell segmentation quality in multiplexed tissue images
Jul 11, 2023
Position-Specific Enrichment Ratio Matrix scores predict antibody variant properties from deep sequencing data
Jul 11, 2023
A workflow combining single-cell CRISPRi screening and a supervised autoencoder neural network to detect subtle transcriptomic perturbations induced by lncRNA Knock-Down
Jul 11, 2023
Utility of language model and physics-based approaches in modifying MHC Class-I immune-visibility for the design of vaccines and therapeutics
Jul 11, 2023
ARCTIC-3D: Automatic Retrieval and ClusTering of Interfaces in Complexes from 3D structural information
Jul 11, 2023
kGWASflow: a modular, flexible, and reproducible Snakemake workflow for k-mers-based GWAS
Jul 11, 2023
Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment
Jul 11, 2023
Petascale Homology Search for Structure Prediction
Jul 11, 2023
A divide and conquer approach (DACA) to predict high fidelity structure of large multidomain protein BRWD1
Jul 11, 2023
Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein
Jul 11, 2023
Self-supervised Benchmarking for scRNAseq Clustering
Jul 10, 2023
Pasa: Leverage population pangenome graph to scaffold prokaryote genome assemblies.
Jul 10, 2023
ENTRAIN: integrating trajectory inference and gene regulatory networks with spatial data to co-localize the receptor-ligand interactions that specify cell fate
Jul 10, 2023
Quantifying Cell-State Densities in Single-Cell Phenotypic Landscapes using Mellon
Jul 10, 2023
Prediction of Alzheimer's Disease from Single Cell Transcriptomics Using Deep Learning
Jul 10, 2023
Spatial pattern and differential expression analysis with spatial transcriptomic data
Jul 09, 2023
Indexing and searching petabyte-scale nucleotide resources
Jul 09, 2023
A microRNA-based Johne's disease diagnostic predictive system: preliminary results
Jul 09, 2023
Efficient High-Quality Metagenome Assembly from Long Accurate Reads using Minimizer-space de Bruijn Graphs
Jul 08, 2023
Mass2SMILES: deep learning based fast prediction of structures and functional groups directly from high-resolution MS/MS spectra.
Jul 08, 2023
Dromi: Python package for parallel computation of similarity measures among vector-encoded sequences
Jul 07, 2023
Leveraging Permutation Testing to Assess Confidence in Positive-Unlabeled Learning Applied to High-Dimensional Biological Datasets
Jul 07, 2023
Epigenetic Germline Variants Predict Cancer Prognosis and Risk and Distribute Uniquely in Topologically Associating Domains
Jul 07, 2023
SPIN-CGNN: Improved fixed backbone protein design with contact map-based graph construction and contact graph neural network
Jul 07, 2023
Deep FASTQ and BAM co-compression in Genozip 15
Jul 07, 2023
Accelerated computations for iterative-solver techniques in single-step BLUP models
Jul 07, 2023
Spontanously breaking of symmetry in overlapping cell instance segmentation using diffusion models
Jul 07, 2023
SpaceANOVA: Spatial co-occurrence analysis of cell types in multiplex imaging data using point process and functional ANOVA
Jul 07, 2023
Semi-supervised integration of single-cell transcriptomics data
Jul 07, 2023
Codon usage bias study of the Vitamin D receptor (VDR) gene of Multiple Sclerosis and Diabetes-1 patients
Jul 07, 2023
Breaking Down Cell-Free DNA Fragmentation: A Markov Model Approach
Jul 07, 2023
Prospects for a sequence-based taxonomy of influenza A virus subtypes
Jul 07, 2023
RamanSPy: An open-source Python package for integrative Raman spectroscopy data analysis
Jul 07, 2023
SynerGPT: In-Context Learning for Personalized Drug Synergy Prediction and Drug Design
Jul 07, 2023
Pan-cancer analysis reveals embryonic and hematopoietic stem cell signatures to distinguish different cancer subtypes
Jul 07, 2023
Exploring multi-omics latent embedding spaces for characterizing tumor heterogeneity and tumoral fitness effects
Jul 07, 2023
Reusability Report: Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients
Jul 07, 2023
Learning Complete Protein Representation by Deep Coupling of Sequence and Structure
Jul 07, 2023
scARE: Attribution Regularization for Single Cell Representation Learning
Jul 07, 2023
Network-based prediction approach for cancer-specific driver missense mutations using a graph neural network
Jul 07, 2023
Exploring Leishmania linear motifs directing protein secretion, sorting and autophagy
Jul 07, 2023
Deep dynamical modelling of developmental trajectories with temporal transcriptomics
Jul 07, 2023
DeepNeuropePred: a robust and universal tool to predict cleavage sites from neuropeptide precursors by protein language model
Jul 07, 2023
SPAT: Surface Protein Annotation Tool
Jul 07, 2023
Using Published Pathway Figures in Enrichment Analysis and Machine Learning
Jul 07, 2023
DeepCristae, a CNN for the restoration of mitochondria cristae in live microscopy images
Jul 05, 2023
msqrob2PTM: differential abundance and differential usage analysis of MS-based proteomics data at the post-translational modification and peptidoform level
Jul 05, 2023
ODAMNet: a Python package to identify molecular relationships between chemicals and rare diseases using overlap, active module and random walk approaches
Jul 05, 2023
ESGq: Alternative Splicing events quantification across conditions based on Event Splicing Graphs
Jul 05, 2023
ABDS: tool suite for analyzing biologically diverse samples
Jul 05, 2023
Hostile: accurate host decontamination of microbial sequences
Jul 05, 2023
Molecular and Quantum Mechanical Studies of Interaction Between Tetrahydrocurcumin Derivative and PCSK9 Protein to Provide a Basis for an Oral Pill to Remove Bad Cholesterol
Jul 05, 2023
Accelerated somatic mutation calling for whole-genome and whole-exome sequencing data from heterogenous tumor samples
Jul 04, 2023
A pre-trained large language model for translating single-cell transcriptome to proteome
Jul 04, 2023
Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
Jul 04, 2023
Molecular Dynamics Simulations on Quercetin-3-(6-Malonylglucoside) From Morus alba Shows Optimal Inhibition of Bcl-2 with Favorable Anti-Tumor Activities.
Jul 04, 2023
Improved protein complex prediction with AlphaFold-multimer by denoising the MSA profile
Jul 04, 2023
Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species
Jul 04, 2023
Feature selection by replicate reproducibility and non-redundancy
Jul 04, 2023
ColabDock: inverting AlphaFold structure prediction model for protein-protein docking with experimental restraints
Jul 04, 2023
Multi-view integration of microbiome data for predicting host disease and identifying disease-associated features
Jul 04, 2023
Robust Feature Selection strategy detects a panel of microRNAs as putative diagnostic biomarkers in Breast Cancer
Jul 04, 2023
ColabSeg: An interactive tool for editing, processing, and visualizing membrane segmentations from cryo-ET data
Jul 04, 2023
Identification of critical cell-types using genetic modules: A case study of neurodevelopmental disorders
Jul 04, 2023
T4SEpp: a pipeline integrated with protein language models effectively predicting bacterial type IV secreted effectors
Jul 03, 2023
Identification and characterization of specific motifs in effector proteins of plant parasites using MOnSTER.
Jul 03, 2023
Reconstructing the Transcriptional Regulatory Network of Probiotic L. reuteri is Enabled by Transcriptomics and Machine Learning
Jul 03, 2023
PanTA: An ultra-fast method for constructing large and growing microbial pangenomes
Jul 03, 2023
In silico characterization of Protein L-Iso-Aspartate-O-Methyltransferases (PIMT) of Shigella flexner
Jul 03, 2023
EEG Signal Processing to Control a Finger Rehabilitation System
Jul 03, 2023
Mitigating autocorrelation during spatially resolved transcriptomics data analysis
Jul 02, 2023
New genome scale network modeling and mining workflow for detecting metabolic changes induced by exposure to chemicals
Jul 02, 2023
Entropy-based decoy generation methods for accurate FDR estimation in large-scale metabolomics annotations.
Jul 02, 2023
Optimal Transport Method-Based Gene Filter (GF) Denoising Algorithm for Enhancing Spatially Resolved Transcriptomics Data
Jul 02, 2023
Identification of treatment-responsive genes in spatial transcriptomics data by leveraging injection site information
Jul 02, 2023
P-PPI: accurate prediction of peroxisomal protein-protein interactions (P-PPI) using deep learning-based protein sequence embeddings
Jul 02, 2023
Concise functional enrichment of ranked gene lists
Jul 02, 2023
Deep learning microstructure estimation of developing brains from diffusion MRI: a newborn and fetal study
Jul 02, 2023
CHAPERONg: A tool for automated GROMACS-based molecular dynamics simulations and trajectory analyses
Jul 02, 2023
Easing OMERO adoption with ezomero
Jul 01, 2023
Juggling offsets unlocks RNA-seq tools for fast scalable differential usage, aberrant splicing and expression analyses.
Jul 01, 2023
Pan-cancer characterization of ncRNA synergistic competition uncovers potential carcinogenic biomarkers
Jul 01, 2023
Flexible Protein-Protein Docking with a Multi-Track Iterative Transformer
Jul 01, 2023
A more expressive spline representation for SBML models improves code generation performance in AMICI
Jul 01, 2023
Discovering Matrix Adducts for Enhanced Metabolite Profiling with Stable Isotope-Labeled MALDI-MSI
Jun 30, 2023
A Molecular Communication model for cellular metabolism
Jun 30, 2023
Scalable, accessible, and reproducible reference genome assembly and evaluation in Galaxy
Jun 30, 2023
OrthoPhyl - A turn-key solution for large scale whole genome bacterial phylogenomics
Jun 30, 2023
Clinical super-resolution computed tomography of bone microstructure: application in musculoskeletal and dental imaging
Jun 30, 2023
PSite: inference of read-specific P-site offsets for ribosomal footprints
Jun 30, 2023
Quantitative assessment of single-cell RNA-seq clustering with CONCORDEX
Jun 30, 2023
Machine learning of enhancer-promoter specificity based on enhancer perturbation studies reveals a distinct class of enhancers.
Jun 30, 2023
A Random Matrix Approach to Single Cell RNA-seq Analysis
Jun 30, 2023
DrugGPT: A GPT-based Strategy for Designing Potential Ligands Targeting Specific Proteins
Jun 30, 2023
Contextualising the developability risk of antibodies with lambda light chains using enhanced therapeutic antibody profiling
Jun 30, 2023
Integrative analysis of microbial 16S gene and shotgun metagenomic sequencing data improves statistical efficiency
Jun 30, 2023
Nanopore Adaptive Sampling Enriches for Antimicrobial Resistance Genes in Microbial Communities
Jun 30, 2023
A closer look at Type I left-handed β-helices provides a better understanding in their sequence-structure relationship: towards their rational design
Jun 29, 2023
Morc1 re-establishes heterochromatin on activated transposons and shapes the host transcriptome in gonocytes
Jun 29, 2023
Optimizing Proteomics Data Differential Expression Analysis via High-Performing Rules and Ensemble Inference
Jun 29, 2023
Mixed data analysis detected Endocrine Fibroblast Growth Factors (FGF19, FGF21, and FGF23) as Prognostic and Diagnostic Markers of Colorectal Neoplasia and Carcinoma
Jun 29, 2023
Clustering the Planet: An Exascale Approach to Determining Global Climatype Zones
Jun 29, 2023
Six novel nsSNPs affect RUNX1 gene may leading to Acute Myeloid Leukemia (AML) using Bioinformatics approach
Jun 29, 2023
Automated Extraction and Visualization of Metabolic Networks from Biomedical Literature Using a Large Language Model
Jun 29, 2023
Computational investigation of cis-1,4-polyisoprene binding to the latex clearing protein LcpK30
Jun 29, 2023
Prediction of tumor-specific splicing from somatic mutations as a source of neoantigen candidates
Jun 29, 2023
Scalable Integration of Multiomic Single Cell Data Using Generative Adversarial Networks
Jun 29, 2023
Identification of three distinct cell populations for urate excretion in human kidney
Jun 29, 2023
Semi-automated retrieval of chemical and phylogenetic information from natural products literature
Jun 29, 2023
Development of a CMS Classifier for Clinical CRC Samples
Jun 29, 2023
nf-core/marsseq: systematic pre-processing pipeline for MARS-seq experiments
Jun 29, 2023
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Jun 28, 2023
SpatialSPM: Statistical parametric mapping for the comparison of gene expression pattern images in multiple spatial transcriptomic datasets
Jun 28, 2023
FISHtoFigure: An easy-to-use tool for rapid, multi-target partitioning and analysis of sub-cellular mRNA transcripts in smFISH data
Jun 28, 2023
Design, Synthesis, Molecular Docking and Biological Activity of Pyrazolopyridines as Promising Lead Candidates Against Mycobacterium tuberculosis
Jun 28, 2023
Inference of Genomic Landscapes using Ordered Hidden Markov Models with Emission Densities (oHMMed)
Jun 28, 2023
Generation of Super-resolution Images from Barcode-based Spatial Transcriptomics Using Deep Image Prior
Jun 28, 2023
SHARK enables homology assessment in unalignable anddisordered sequences
Jun 28, 2023
Enteropathway: the metabolic pathway database for the human gut microbiota
Jun 28, 2023
CHARR efficiently estimates contamination from DNA sequencing data
Jun 28, 2023
SpheroScan: A User-Friendly Deep Learning Tool for Spheroid Image Analysis
Jun 28, 2023
Evolutionary potential of the monkeypox genome arising from interactions with human APOBEC3 enzymes
Jun 28, 2023
MGSurvE: A framework to optimize trap placement for genetic surveillance of mosquito population
Jun 27, 2023
Metabolic-Pathway-Presence-Heatmap (MPPH):Constructing phylogenetic trees based on metabolic pathways.
Jun 27, 2023
DENetwork: Unveiling Regulatory and Signaling Networks Behind Differentially-Expressed Genes
Jun 27, 2023
FM3VCF: A Software Library for Accelerating the Loading of Large VCF Files in Genotype Data Analyses
Jun 27, 2023
Catching a wave: on the suitability of traveling-wave solutions in epidemiological modeling
Jun 26, 2023
Fusion Neural Network (FusNet) for predicting protein-mediated loops
Jun 26, 2023
Incorporating physics to overcome data scarcity in predictive modeling of protein function: a case study of BK channels
Jun 26, 2023
Extensible benchmarking of methods that identify and quantify polyadenylation sites from RNA-seq data
Jun 26, 2023
Genome-scale metabolic model predicts mechanistic differences in metabolic gradient of spatially resolved small intestine villi
Jun 26, 2023
Optimizer's dilemma: optimization strongly influences model selection in transcriptomic prediction
Jun 26, 2023
PepFlow: direct conformational sampling from peptide energy landscapes through hypernetwork-conditioned diffusion
Jun 26, 2023
Small allelic variants are a source of ancestral bias in structural variant breakpoint placement
Jun 26, 2023
Rapid and accurate multi-phenotype imputation for millions of individuals
Jun 26, 2023
Twenty novel nsSNPs may affect FLT3 gene leading to Acute Myeloid Leukemia (AML) using in silico analysis
Jun 26, 2023
BioLiP2: a database for biological unit-based protein-ligand interactions
Jun 26, 2023
Rocket-miR, a Translational Launchpad for miRNA-based Antimicrobial Drug Development
Jun 25, 2023
Transcriptomic Enrichment of Ferroptosis-Related Gene ACSL4 in Advanced Hepatic Fibrosis/Cirrhosis: Bioinformatics Analysis and Experimental validation
Jun 25, 2023
wTSA-CRAFT : an open-access web server for rapid analysis of thermal shift assay experiments
Jun 25, 2023
Multi_CycGT: a DL-based multimodal model for membrane permeability prediction of cyclic peptides
Jun 24, 2023
Fractional Hitting Sets for Efficient and Lightweight Genomic Data Sketching
Jun 24, 2023
RIBO-former: leveraging ribosome profiling information to improve the detection of translated open reading frames.
Jun 24, 2023
Trajectories of atherosclerotic cardiovascular disease risk scores as a predictor for incident chronic kidney disease
Jun 24, 2023
Brooklyn plots to identify co-expression dysregulation in single cell sequencing
Jun 24, 2023
A method for storing information in DNA with improved dropout tolerance
Jun 24, 2023
QuantUMS: uncertainty minimisation enables confident quantification in proteomics
Jun 24, 2023
Exact Sketch-Based Read Mapping
Jun 24, 2023
Co-linear Chaining on Pangenome Graphs
Jun 24, 2023
A Clear, Legible, Explainable, Transparent, and Elucidative (CLETE) Binary Classification Platform for Tabular Data
Jun 24, 2023
SEGMENTATION OF DYNAMIC TOTAL-BODY -FDG PET IMAGES USING UNSUPERVISED CLUSTERING
Jun 24, 2023
Pathway Centric Analysis for single-cell RNA-seq and Spatial Transcriptomics Data with GSDensity
Jun 24, 2023
FLOP: Tasks for Fitness Landscapes Of Protein wildtypes
Jun 24, 2023
ShinyMultiome.UiO: An interactive open-source framework utilizing Seurat Objects for visualizing single-cell Multiomes
Jun 24, 2023
Re-investigating the correctness of decoy-based false discovery rate control in proteomics tandem mass spectrometry
Jun 24, 2023
Rat Deconvolution as Knowledge Miner for Immune Cell Trafficking from Toxicogenomics Databases
Jun 24, 2023
The landscape of microRNA interactions annotation: analysis of three rare disorders as case study
Jun 24, 2023
DeepRank-GNN-esm: A Graph Neural Network for Scoring Protein-Protein Models using Protein Language Model
Jun 24, 2023
Accurate prediction of protein assembly structure by combining AlphaFold and symmetrical docking
Jun 24, 2023
A mean-field to capture asynchronous irregular dynamics of conductance-based networks of adaptive quadratic integrate-and-fire neuron models
Jun 24, 2023
Vocabulary Matters: An Annotation Pipeline and Two Deep Learning Algorithms for Enzyme Named Entity Recognition
Jun 24, 2023
Bioinformatic Surveillance Leads to Discovery of Two Novel Putative Bunyaviruses Associated with Black Soldier Fly
Jun 24, 2023
MOCHA: Advanced statistical modeling of scATAC-seq data enables functional genomic inference in large human disease cohorts
Jun 24, 2023
Fine-tuning Protein Embeddings for GeneralizableAnnotation Propagation
Jun 24, 2023
Peak-agnostic high-resolution cis-regulatory circuitry mapping using single cell multiome data
Jun 24, 2023
Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity
Jun 23, 2023
Revisiting annotation of Schistosoma mansoni Micro-Exon Gene (MEG) family
Jun 23, 2023
GeNNius: An ultrafast drug-target interaction inference method based on graph neural networks
Jun 23, 2023
Deep learning, data ramping, and uncertainty estimation for detecting artifacts in large, imbalanced databases of MRI images
Jun 23, 2023
netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity
May 05, 2023
JLOH: Inferring Loss of Heterozygosity Blocks from Sequencing Data
May 05, 2023
Active and Allosteric Site Binding MOLECULAR MECHANICS-QUANTUM MECHANICS studies of STEVIOSIDE Derivative in PCSK9 Protein Intended to provide a safe Antilipidemic agent
May 05, 2023
ImSpiRE: Image feature-aided spatial resolution enhancement method
May 05, 2023
Diversity of the bacterial and viral communities in the tropical horse tick, Dermacentor nitens in Colombia
May 05, 2023
A Bayesian Noisy Logic Model for Inference of Transcription Factor Activity from Single Cell and Bulk Transcriptomic Data
May 05, 2023
Orphan Drugs and Rare Diseases: Unveiling Biological Patterns through Drug Repurposing
May 05, 2023
Worth the weight: Sub-Pocket EXplorer (SubPEx), a weighted-ensemble method to enhance binding-pocket conformational sampling
May 05, 2023
Protein Engineering for Thermostability through Deep Evolution
May 05, 2023
The evolution of splice site sequence preference is linked to the U6 snRNA m6A methyltransferase METTL16
May 05, 2023
Drug resistance prediction for Mycobacterium tuberculosis with reference graphs
May 04, 2023
Enhancing drug repurposing on graphs by integrating drug molecular structure as feature
May 04, 2023
Reverse Engineering DNA Origami Nanostructure Designs from Raw Scaffold and Staple Sequence Lists
May 04, 2023
A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation
May 04, 2023
HiPhase: Jointly phasing small and structural variants from HiFi sequencing
May 04, 2023
cellsnake: a user-friendly tool for single cell RNA sequencing analysis
May 04, 2023
GARSA: An integrative pipeline for genome wide association studies and polygenic risk score inference in admixed human populations
May 04, 2023
Single-cell Mayo Map (scMayoMap): an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis
May 04, 2023
ESKtides: a comprehensive database and mining method for ESKAPE-derived peptides
May 04, 2023
Integrating gene mutation spectra from tumors and the general population with gene expression topological networks to identify novel cancer driver genes
May 03, 2023
Scalable Log-ratio Lasso Regression Enhances Microbiome Feature Selection for Predictive Models
May 03, 2023
Enzyme stability-activity trade-off: new insights from protein stability weaknesses and evolutionary conservation
May 03, 2023
Restrander: rapid orientation and QC of long-read cDNA data
May 03, 2023
Analysis of tandem mass spectrometry data with CONGA: Combining Open and Narrow searches with Group-wise Analysis
May 03, 2023
An image segmentation method based on the spatial correlation coefficient of Local Moran's I
May 02, 2023
memo-eQTL: DNA methylation modulated genetic variant effect on gene transcriptional regulation
May 02, 2023
Automatic annotation of the bHLH gene family in plants
May 02, 2023
Simulation of 69 microbial communities indicates sequencing depth and false positives are major drivers of bias in Prokaryotic metagenome-assembled genome recovery
May 02, 2023
DrugMechDB: A Curated Database of Drug Mechanisms
May 02, 2023
An in-silico approach to study the molecular interaction of the PINK1 kinase domain with Parkin Ubl domain
May 02, 2023
A 2D convolutional neural network for taxonomic classification applied to viruses in the phylum Cressdnaviricota
May 02, 2023
scDisInFact: disentangled learning for integration and prediction of multi-batch multi-condition single-cell RNA-sequencing data
May 02, 2023
Molecule-Morphology Contrastive Pretraining for Transferable Molecular Representation
May 02, 2023
Variance Analysis of LC-MS Experimental Factors and Their Impact on Machine Learning
May 02, 2023
SAP: Synteny-aware gene function prediction for bacteria using protein embeddings
May 02, 2023
Joint representation of molecular networks from multiple species improves gene classification
May 02, 2023
Syndecan-4 is the Key Proteoglycan Mediating LPS-induced Sepsis-associated Lung Injury
May 02, 2023
MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
May 02, 2023
Computational fitness estimates of SARS-CoV-2 mutations affecting spike protein binding to antibodies and ACE2
May 02, 2023
Building Trust in Deep Learning-based Immune Response Predictors with Interpretable Explanations
May 02, 2023
Building flexible and robust analysis frameworks for molecular subtyping of cancers
May 01, 2023
Only three principal components account for inter-embryo variability of the spindle length over time.
May 01, 2023
Automatic Classification of Normal and Abnormal Cell Division Using Deep Learning Analysis of Mitosis Videos
May 01, 2023
scGPT: Towards Building a Foundation Model for Single-Cell Multi-omics Using Generative AI
May 01, 2023
Automatic cell type harmonization and integration across Human Cell Atlas datasets
May 01, 2023
Improving AlphaFold2-based Protein Tertiary Structure Prediction with MULTICOM in CASP15
May 01, 2023
Annotation-free pathology images characterize tumor immune microenvironment in breast cancer by weakly supervised contrastive learning
Apr 30, 2023
Negligible effects of read trimming on the accuracy of germline short variant calling in the human genome
Apr 30, 2023
Exploring The Ability Of Machine Learning-Based Virtual Screening Models To Identify The Functional Groups Responsible For Binding
Apr 30, 2023
Semantic Representation of Neural Circuit Knowledge in Caenorhabditis elegans
Apr 30, 2023
Combining LIANA and Tensor-cell2cell to decipher cell-cell communication across multiple samples
Apr 30, 2023
Charting the alternative usage of protein repeated regions in evolution and its implication for protein interactions
Apr 30, 2023
Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data
Apr 29, 2023
xQTLbiolinks: a comprehensive and scalable tool for integrative analysis of molecular QTLs
Apr 29, 2023
Identification of disease mechanisms and novel disease genes using clinical concept embeddings learned from massive amounts of biomedical data.
Apr 29, 2023
Network inference from temporal phosphoproteomics informed by protein-protein interactions
Apr 29, 2023
Integrated analysis of spatial multi-omics with SpatialGlue
Apr 29, 2023
Computational Insight into Anti-Obesity Effects of Combined Some Phytobiotics to GLP1R (Glucagon-Like Peptide 1 Receptor) Protein in Anas javanica
Apr 29, 2023
Improved Quality Metrics for Association and Reproducibility in Chromatin Accessibility Data Using Mutual Information
Apr 29, 2023
APOE-NOTCH Axis Governs Elastogenesis During Human Cardiac Valve Remodeling
Apr 29, 2023
TISSUE: uncertainty-calibrated prediction of single-cell spatial transcriptomics improves downstream analyses
Apr 29, 2023
Self-supervision advances morphological profiling by unlocking powerful image representations
Apr 29, 2023
Bacterial colony size growth estimation by deep learning
Apr 29, 2023
The Influence of Brain MRI Defacing Algorithms on Brain-Age Predictions via 3D Convolutional Neural Networks
Apr 29, 2023
Identification of transcription factor co-binding patterns with non-negative matrix factorization
Apr 29, 2023
scEpiTools: a database to comprehensively interrogate analytic tools for single-cell epigenomic data
Apr 29, 2023
MitoSort: robust demultiplexing of pooled single-cell genomics data using endogenous germline mitochondrial variants
Apr 28, 2023
MetPlast: an R package to evaluate Metabolic Plasticity using Information Theory statistical framework
Apr 28, 2023
Interpretable dimensionality reduction and classification of mass spectrometry imaging data in a visceral pain model via non-negative matrix factorization
Apr 28, 2023
VISTA: Visualizing the Spatial Transcriptome of the C. elegans Nervous System
Apr 28, 2023
Clade-Specific MPXV PCR Assays
Apr 28, 2023
Learning the Language of Antibody Hypervariability
Apr 28, 2023
CcBHLA: pan-specific peptide-HLA class I binding prediction via Convolutional and BiLSTM features
Apr 28, 2023
RaptorX-Single: single-sequence protein structure prediction by integrating protein language models
Apr 28, 2023
A deep reinforcement learning approach to the optimization of epithelial sheets biofabrication
Apr 28, 2023
DEGAP: Dynamic Elongation of a Genome Assembly Path
Apr 28, 2023
EnGens: a computational framework for generation and analysis of representative protein conformational ensembles
Apr 28, 2023
Interfacial residues in protein-protein complexes are in the eyes of the beholder
Apr 28, 2023
Uncovering the hidden structure of dynamic T cell composition in peripheral blood during cancer immunotherapy: a topic modeling approach
Apr 28, 2023
Riboformer: A Deep Learning Framework for Predicting Context-Dependent Translation Dynamics
Apr 28, 2023
InterOpt: Improved gene expression quantification in qPCR experiments using weighted aggregation of reference genes
Apr 28, 2023
TIME-SERIES CLASSIFICATION FOR PATIENTS UNDER ACTIVE SURVEILLANCE AND SCREENING USING ECHO STATE NETWORK
Apr 28, 2023
Assessment of Total Oocyte Transcripts Representation through Single Ooplasm Biopsy in Bovine with High Reliability
Apr 28, 2023
Uncovering Co-regulatory Modules and Gene Regulatory Networks in the Heart through Machine Learning-based Analysis of Large-scale Epigenomic Data
Apr 28, 2023
KOunt - A reproducible KEGG orthologue abundance workflow
Apr 28, 2023
SeqImprove: Machine Learning Assisted Creation of Machine Readable Sequence Information
Apr 28, 2023
RNAvigate: Efficient exploration of RNA chemical probing datasets
Apr 28, 2023
A benchmark study on current GWAS models in admixed populations
Apr 28, 2023
Plasma-free samples for transcriptomic analysis: a potential alternative to whole blood samples
Apr 28, 2023
Benchmarking Bioinformatic Virus Identification Tools Using Real-World Metagenomic Data across Biomes
Apr 28, 2023
Deep Learning for Protein Structure Prediction: Advancements in Structural Bioinformatics
Apr 28, 2023
STAPLER: Efficient learning of TCR-peptide specificity prediction from full-length TCR-peptide data
Apr 28, 2023
Surfaces: A software to quantify and visualize interactions within and between proteins and ligands
Apr 28, 2023
DeepUMQA3: a web server for model quality assessment of protein complexes
Apr 28, 2023
Supervised biological network alignment with graph neural networks
Apr 28, 2023
Genome-wide analysis of CRISPR perturbations indicates that enhancers act multiplicatively and without epistatic-like interactions
Apr 27, 2023
NextPolish2: a repeat-aware polishing tool for genomes assembled using HiFi long reads
Apr 27, 2023
De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep Learning Framework
Apr 26, 2023
VirtualFlow 2.0 - The Next Generation Drug Discovery Platform Enabling Adaptive Screens of 69 Billion Molecules
Apr 26, 2023
VODKA2: An accurate method to detect copy-back and deletion viral genomes from next-generation sequencing data
Apr 25, 2023
Automatic quantification of disgust taste reactivity in mice using machine learning
Apr 25, 2023
Representation Learning to Effectively Integrate and Interpret Omics Data
Apr 25, 2023
Chaotic aging: Intrinsically disordered proteins in aging-related processes
Apr 25, 2023
Histone methylation has a direct metabolic role in human cells
Apr 25, 2023
scDEED: a statistical method for detecting dubious 2D single-cell embeddings
Apr 25, 2023
Comparative study of the mechanism of natural compounds with similar structures using docking and transcriptome data for improving in silico herbal medicine experimentations
Apr 25, 2023
AtlasXplore: a web platform for visualizing and sharing spatial epigenome data
Apr 25, 2023
SurVIndel2: improving local CNVs calling from next-generation sequencing using novel hidden information
Apr 25, 2023
Diagnostic Evidence Gauge of Spatial Transcriptomics (DEGAS): Using transfer learning to map clinical data to spatial transcriptomics in prostate cancer
Apr 25, 2023
Model-based dimensionality reduction for single-cell RNA-seq using generalized bilinear models
Apr 25, 2023
CoSIA: an R Bioconductor package for CrOss Species Investigation and Analysis
Apr 25, 2023
Molecular insight into the mechanism of action of some beneficial flavonoids for the treatment of Parkinson's Disease
Apr 25, 2023
hipFG: High-throughput harmonization and integration pipeline for functional genomics data
Apr 25, 2023
Accuracy and Reliability of a Suite of Digital Measures of Walking Generated Using a Wrist-worn Sensor: Performance Characterization Study
Apr 25, 2023
Ranking Antibody Binding Epitopes and Proteins Across Samples from Whole Proteome Tiled Linear Peptides
Apr 25, 2023
Capture-recapture for -omics data meta-analysis
Apr 25, 2023
ORFeus: A Computational Method to Detect Programmed Ribosomal Frameshifts and Other Non-Canonical Translation Events
Apr 25, 2023
3D structural human interactome reveals proteome-wide perturbations by disease mutations
Apr 25, 2023
Topology-Aware Focal Loss for 3D Image Segmentation
Apr 24, 2023
BEERS2: RNA-Seq simulation through high fidelity in silico modeling
Apr 24, 2023
standR: a Bioconductor package for analysing transcriptomic Nanostring GeoMx DSP data
Apr 24, 2023
Metabolic predictors of response to immune checkpoint blockade therapy
Apr 21, 2023
Protein family annotation for the Unified Human Gastrointestinal Proteome by DPCfam clustering
Apr 21, 2023
Reference-free and cost-effective automated cell type annotation with GPT-4 in single-cell RNA-seq analysis
Apr 21, 2023
Protein multiple conformations prediction using multi-objective evolution algorithm
Apr 21, 2023
Disruption of metazoan gene regulatory networks in cancer alters the balance of co-expression between genes of unicellular and multicellular origins
Apr 21, 2023
Exploring the Landscape of Spatial Transcriptome Analysis: Introducing STASH, a Database of Spatial Transcriptome Tools
Apr 21, 2023
Alternative splicing impacts microRNA regulation within coding regions
Apr 21, 2023
Transcript Assembly and Annotations: Bias and Adjustment
Apr 21, 2023
The Cell Subtypes Selection by Genes (CSSG) algorithm for discovering cell populations in high resolution
Apr 21, 2023
GSR-DB: a manually curated and optimised taxonomical database for 16S rRNA amplicon analysis
Apr 21, 2023
D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response
Apr 21, 2023
Fibertools: fast and accurate DNA-m6A calling using single-molecule long-read sequencing
Apr 21, 2023
Kronos: A computational tool to facilitate biological rhythmicity analysis
Apr 21, 2023
TopoDoE: A Design of Experiment strategy for selection and refinement in ensembles of executable Gene Regulatory Networks
Apr 21, 2023
Key common genes and pathways in ulcerative colitis and ankylosing spondylitis based on bioinformatics analysis
Apr 21, 2023
The Promise and Pitfalls of Prophages
Apr 21, 2023
AI becomes a masterbrain scientist
Apr 21, 2023
CellHeap: A scRNA-seq workflow for large-scalebioinformatics data analysis
Apr 21, 2023
AbFold -- an AlphaFold Based Transfer Learning Model for Accurate Antibody Structure Prediction
Apr 21, 2023
VoroIF-GNN: Voronoi tessellation-derived protein-protein interface assessment using a graph neural network
Apr 21, 2023
Pathfinder: protein folding pathway prediction based on conformational sampling
Apr 21, 2023
Scoary2: Rapid association of phenotypic multi-omics data with microbial pan-genomes
Apr 21, 2023
Impact of water models on structure and dynamics of ligand-transport tunnels in enzymes derived from molecular dynamics simulations
Apr 21, 2023
Automatic recognition of complementary strands: Lessons regarding machine learning abilities in RNA folding
Apr 21, 2023
Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
Apr 21, 2023
Machine learning detection of SARS-CoV-2 high-risk variants
Apr 20, 2023
Contigs directed gene annotation (ConDiGA) for accurate protein sequence database construction in metaproteomics
Apr 20, 2023
Mobilisation and analyses of publicly available SARS-CoV-2 data for pandemic responses
Apr 20, 2023
Matrisome AnalyzeR: A suite of tools to annotate and quantify ECM molecules in big datasets across organisms
Apr 20, 2023
Efficient k-mer based curation of raw sequence data: application in Drosophila suzukii
Apr 20, 2023
MACI: A machine learning-based approach to identify drug classes of antibiotic resistance genes from metagenomic data
Apr 20, 2023
A Comprehensive Benchmark Study on Biomedical Text Generation and Mining with ChatGPT
Apr 20, 2023
The covariance environment defines cellular niches for spatial inference
Apr 20, 2023
Investigation of the usefulness of liver-specific deconvolution method toward legacy data utilization
Apr 20, 2023
A novel Energy Landscape construction method incorporating the Latent Dirichlet Allocation topic model and the pairwise Maximum Entropy model, revealing the significant contribution of Bactericides to the development of Inflammatory Bowel Disease
Apr 20, 2023
Exhaustive benchmarking of de novo assembly methods for eukaryotic genomes
Apr 20, 2023
YACHT: an ANI-based statistical test to detect microbial presence/absence in a metagenomic sample
Apr 20, 2023
Pyro: A Comprehensive Pipeline for Eukaryotic Genome Assembly
Apr 20, 2023
Fine Tuning Rigid Body Docking Results Using the Dreiding Force Field: A Computational Study of 36 Known Nanobody-Protein Complexes
Apr 19, 2023
Predicting Distant Recurrences in Invasive Breast Carcinoma Patients Using Clinicopathological Data: A cross-institutional and AI-based study
Apr 19, 2023
DeepCORE: An interpretable multi-view deep neural network model to detect co-operative regulatory elements
Apr 19, 2023
BrainTACO: An Explorable Multi-Scale Multi-Modal Brain Transcriptomic And Connectivity Data Resource
Apr 19, 2023
BREADR: An R Package for the Bayesian Estimation of Genetic Relatedness from Low-coverage Genotype Data
Apr 18, 2023
AlcoR: alignment-free simulation, mapping, and visualization of low-complexity regions in biological data
Apr 18, 2023
PaxDB 5.0: curated protein quantification data suggests adaptive proteome changes
Apr 18, 2023
The effect of removing repeat-induced overlaps in de novo assembly
Apr 18, 2023
An explainable graph neural framework to identify cancer-associated intratumoral microbial communities
Apr 18, 2023
Screening and identification of key biomarkers in diabetic kidney disease and its complications: Evidence from bioinformatics and next generation sequencing data analysis
Apr 18, 2023
mitoSpliter: a mitochondrial RNA variants-based method for single-cell RNA-seq analysis of multiplexed samples
Apr 18, 2023
CamoTSS: analysis of alternative transcription start sites for cellular phenotypes and regulatory patterns from 5' scRNA-seq data
Apr 18, 2023
An accurate and interpretable model to predict antimicrobial resistance in One Health settings
Apr 18, 2023
Transcriptome Complexity Disentangled: A Regulatory Elements Approach
Apr 18, 2023
NucleosomeDB - a database of 3D nucleosome structures and their complexes with comparative analysis toolkit
Apr 18, 2023
DESpace: spatially variable gene detection via differential expression testing of spatial clusters
Apr 18, 2023
Integrating Expert Knowledge with Deep Learning Improves QSAR Models for CADD Modeling
Apr 18, 2023
How AlphaFold shaped the structural coverage of the human transmembrane proteome
Apr 18, 2023
Rapid protein-protein interaction network creation from multiple sequence alignments with Deep Learning
Apr 17, 2023
SPADE: Spatial Deconvolution for Domain Specific Cell-type Estimation
Apr 17, 2023
Discovery of novel multi-functional peptides by using protein language models and graph-based deep learning
Apr 17, 2023
RNA covariation at helix-level resolution for the identification of evolutionarily conserved RNA structure
Apr 17, 2023
Assisting and Accelerating NMR Assignment with Restrainted Structure Prediction
Apr 17, 2023
GraphPart: Homology partitioning for biological sequence analysis
Apr 17, 2023
Assessing the quality of comparative genomics data and results with the cogeqc R/Bioconductor package
Apr 17, 2023
Mapping lineage-traced cells across time points with moslin
Apr 17, 2023
Reply to: The pitfalls of negative data bias for the T-cell epitope specificity challenge
Apr 17, 2023
Charting spatial ligand-target activity using Renoir
Apr 17, 2023
An Equivariant Generative Framework for Molecular Graph-Structure Co-Design
Apr 17, 2023
Weakly supervised contrastive learning infers molecular subtypes and recurrence risk of breast cancer from pathology images
Apr 17, 2023
Efficient and Robust Search of Microbial Genomes via Phylogenetic Compression
Apr 16, 2023
Computational pathology infer clinically relevant protein levels and drug efficacy in breast cancer by weakly supervised contrastive learning
Apr 16, 2023
The Power of Two: integrating deep diffusion models and variational autoencoders for single-cell transcriptomics analysis
Apr 16, 2023
Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
Apr 14, 2023
Do NSm virulence factors in the Bunyavirales order originate from Gn gene duplication?
Apr 14, 2023
Context-Aware Amino Acid Embedding Advances Analysis of TCR-Epitope Interactions
Apr 14, 2023
A mouse-specific model to detect genes under selection in tumors
Apr 14, 2023
Identification of Mirror Repeats in Viral Genomes using FPCB Analysis
Apr 14, 2023
Surface-guided computing to analyze subcellular morphology and membrane-associated signals in 3D
Apr 14, 2023
PhenoCellPy: A Python package for biological cell behavior modeling
Apr 14, 2023
Linear and Neural Network Models for Predicting N-glycosylation in Chinese Hamster Ovary Cells Based on B4GALT Levels
Apr 14, 2023
Ultra-fast genotyping of SNPs and short indels using GPU acceleration
Apr 14, 2023
Ensembles for improved detection of invasive breast cancer in histological images
Apr 14, 2023
A comparison between Greengenes, SILVA, RDP, and NCBI reference databases in four published microbiota datasets
Apr 13, 2023
Barcode-free multiplex plasmid sequencing using Bayesian analysis and nanopore sequencing
Apr 13, 2023
PGSbuilder: An end-to-end platform for human genome association analysis and polygenic risk score predictions
Apr 13, 2023
LinRace: single cell lineage reconstruction using paired lineage barcode and gene expression data
Apr 13, 2023
Wearable-ome meets epigenome: A novel approach to measuring biological age with wearable devices.
Apr 13, 2023
SARS-CoV-2 selectively induces the expression of unproductive splicing isoforms of interferon, class I MHC and splicing machinery genes
Apr 13, 2023
Alignment of spatial transcriptomics data using diffeomorphic metric mapping
Apr 12, 2023
A zero-agnostic model for copy number evolution in cancer
Apr 12, 2023
WormSwin: Instance segmentation of C. elegans using vision transformer
Apr 12, 2023
acorn: an R package for de novo variant analysis
Apr 12, 2023
SpatialCTD: a large-scale TME spatial transcriptomic dataset to evaluate cell type deconvolution for immuno-oncology
Apr 12, 2023
Comparative Clustering (CompaCt) of eukaryote complexomes identifies novel interactions and sheds light on protein complex evolution
Apr 12, 2023
LOCC: a novel visualization and scoring of cutoffs for continuous variables
Apr 12, 2023
Programmed ribosomal frameshifts, and how to find them
Apr 12, 2023
Demultiplex2: robust sample demultiplexing for scRNA-seq
Apr 12, 2023
Accurate prediction of in vivo protein abundances by coupling constraint-based modeling and machine learning
Apr 12, 2023
G2GSnake: A Snakemake workflow for host-pathogen genomic association studies
Apr 12, 2023
Improved interpretability of bacterial genome-wide associations using gene cluster centric k-mers
Apr 12, 2023
Fecal metagenomics to identify biomarkers of food intake in healthy adults: Findings from randomized, controlled, nutrition trials
Apr 11, 2023
Deep Learning and Transfer Learning for Brain Tumor Detection and Classification
Apr 11, 2023
An in-depth comparison of linear and non-linear joint embedding methods for bulk and single-cell multi-omics
Apr 11, 2023
Estimating amino acid substitution models from genome datasets: A simulation study on the performance of estimated models
Apr 10, 2023
ReCom: A semi-supervised approach to ultra-tolerant database search for improved identification of modified peptides
Apr 10, 2023
GALBA: Genome Annotation with Miniprot and AUGUSTUS
Apr 10, 2023
A modular metagenomics analysis system for integrated multi-step data exploration
Apr 09, 2023
Predicting splicing patterns from the transcription factor binding sites in the promoter with deep learning
Apr 09, 2023
Evaluating proteomics imputation methods with improved criteria
Apr 08, 2023
scSPARKL: Apache Spark based parallel analytical framework for the downstream analysis of scRNA-seq data.
Apr 08, 2023
MOViDA: Multi-Omics Visible Drug Activity Prediction with a Biologically Informed Neural Network Model
Apr 08, 2023
Spatial-linked alignment tool (SLAT) for aligning heterogenous slices properly
Apr 08, 2023
Prediction of virus-host association using protein language models and multiple instance learning
Apr 08, 2023
scART: recognizing cell clusters and constructing trajectory from single-cell epigenomic data
Apr 08, 2023
Deep learning of genomic contexts predicts protein co-regulation and function
Apr 08, 2023
Salt corrections for RNA secondary structures in the ViennaRNA package
Apr 08, 2023
Determining the Statistical Significance of the Difference Between Arbitrary Curves: A Spreadsheet Approach
Apr 08, 2023
A Weighted Two-stage Sequence Alignment Framework to Identify DNA Motifs from ChIP-exo Data
Apr 08, 2023
Coding Sequence Insertions in Fungal Genomes are Intrinsically Disordered and can Impart Functionally-Important Properties on the Host Protein
Apr 07, 2023
HCV E1 influences the fitness landscape of E2 and may enhance escape from E2-specific antibodies
Apr 07, 2023
Binary classification machine-learning Unveils Sex-Dependent mutated gene Signatures in Melanoma
Apr 07, 2023
euka: Robust detection of eukaryotic taxa from modern and ancient environmental DNA using pangenomic reference graphs.
Apr 07, 2023
Benchmarking imputation methods for discrete biological data
Apr 07, 2023
A resampling-based approach to share reference panels
Apr 07, 2023
Integrating multiple single-cell multi-omics samples with Smmit
Apr 06, 2023
Building pangenome graphs
Apr 06, 2023
The pitfalls of negative data bias for the T-cell epitope specificity challenge
Apr 06, 2023
CT Multi-Task Learning with a Large Image-Text (LIT) Model
Apr 06, 2023
M-Ionic: Prediction of metal ion binding sites from sequence using residue embeddings
Apr 06, 2023
SFyNCS detects oncogenic fusions involving non-coding sequences in cancer
Apr 06, 2023
The ENCODE Uniform Analysis Pipelines
Apr 06, 2023
GEGVIC: A workflow to analyze Gene Expression, Genetic Variations and Immune cell Composition of tumor samples using Next Generation Sequencing data
Apr 06, 2023
PPIAT:Target mass spectrometry based Protein-Protein interaction analytics tool
Apr 06, 2023
GGoutlieR: an R package to identify and visualize unusual geo-genetic patterns of biological samples
Apr 06, 2023
Fast genome-based delimitation of Enterobacterales species
Apr 06, 2023
Characterization of proteoform post-translational modifications by top-down and bottom-up mass spectrometry in conjunction with UniProt annotations
Apr 06, 2023
GENI: a web server to identify gene set enrichments in tumor samples
Apr 06, 2023
tauFisher accurately predicts circadian time from a single sample of bulk and single-cell transcriptomic data
Apr 06, 2023
Microbiome Metabolome Integration Platform (MMIP): a web-based platform for microbiome and metabolome data integration and feature identification.
Apr 06, 2023
Multiomics Approach to Understanding Olaparib Resistance and Predicting Drug Response
Apr 06, 2023
Meta-analysis of gene activity (MAGA) contributions and correlation with gene expression, through GAGAM.
Apr 06, 2023
THAPBI PICT - a fast, cautious, and accurate metabarcoding analysis pipeline
Apr 06, 2023
Genomics to Notebook (g2nb): extending the electronic notebook to address the challenges of bioinformatics analysis
Apr 06, 2023
Assessment of the normal cell contamination impact on tumour samples analysed with SNP arrays: The signal confusion nightmare.
Apr 06, 2023
RSim: A Reference-Based Normalization Method via Rank Similarity
Apr 06, 2023
BetaBuddy: An end-to-end computer vision pipeline for the automated analysis of insulin secreting β-cells
Apr 06, 2023
XClone: detection of allele-specific subclonal copy number variations from single-cell transcriptomic data
Apr 05, 2023
TALLSorts: a T-cell acute lymphoblastic leukaemia subtype classifier using RNA-seq expression data
Apr 05, 2023
Improving deep models of protein-coding potential with a Fourier-transform architecture and machine translation task
Apr 05, 2023
Detecting Anomalous Proteins Using Deep Representations
Apr 05, 2023
Prediction of fast subcellular Ca2+ signals based on subcellular structures in label-free second harmonic generation microscopy measurements
Apr 05, 2023
Comparison of classification accuracy and feature selection between sparse and non-sparse modeling of metabolomics data
Apr 05, 2023
Cell Painting-based bioactivity prediction boosts high-throughput screening hit-rates and compound diversity
Apr 05, 2023
asmbPLS: Adaptive Sparse Multi-block Partial Least Square for Survival Prediction using Multi-Omics Data
Apr 05, 2023
Protein language model powers accurate and fast sequence search for remote homology
Apr 05, 2023
Reconstruction Set Test (RESET): a computationally efficient method for single sample gene set testing based on randomized reduced rank reconstruction error
Apr 05, 2023
DrBERT: A Robust Pre-trained Model in French for Biomedical and Clinical domains
Apr 05, 2023
Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp.
Apr 05, 2023
SEQUENCE VS. STRUCTURE: DELVING DEEP INTO DATA DRIVEN PROTEIN FUNCTION PREDICTION
Apr 04, 2023
MANGEM - a web app for Multimodal Analysis of Neuronal Gene expression, Electrophysiology and Morphology
Apr 04, 2023
A hybrid single-cell demultiplexing strategy that increases both cell recovery rate and calling accuracy
Apr 04, 2023
Reconstruction of Gene Regulatory Networks using sparse graph recovery models
Apr 04, 2023
Dividing out quantification uncertainty allows efficient assessment of differential transcript expression
Apr 04, 2023
Phables: from fragmented assemblies to high-quality bacteriophage genomes
Apr 04, 2023
Using macromolecular electron densities to improve the enrichment of active compounds in virtual screening
Apr 04, 2023
Comparing chromatin contact maps at scale: methods and insights
Apr 04, 2023
The Functional RNA Identification (FRID) Pipeline: Identification of Potential Pseudoknot-Containing RNA Elements as Therapeutic Targets for SARS-CoV-2
Apr 04, 2023
Community structure and temporal dynamics of SARS-CoV-2 epistatic network allows for early detection of emerging variants with altered phenotypes
Apr 03, 2023
Protein language models can capture protein quaternary state
Apr 02, 2023
AI-based novel-chemotype GPCRs drugs: introducing ligand type classifiers and systems biology
Apr 02, 2023
TCR2vec: a deep representation learning framework of T-cell receptor sequence and function
Apr 02, 2023
Recombulator-X: a fast and user-friendly tool for estimating X chromosome recombination rates in forensic genetics
Apr 02, 2023
MOGAT: An Improved Multi-Omics Integration Framework Using Graph Attention Networks
Apr 02, 2023
A Bayesian method to infer copy number clones from single-cell RNA and ATAC sequencing
Apr 02, 2023
CilioGenics: an integrated method and database for predicting novel ciliary genes
Apr 02, 2023
T9GPred: A Comprehensive Computational Tool for the Prediction of Type 9 Secretion System, Gliding Motility and the Associated Secreted Proteins
Apr 02, 2023
Determining epitope specificity of T-cell receptors with transformers
Apr 02, 2023
Deep Learning for Flexible and Site-Specific Protein Docking and Design
Apr 02, 2023
FLUTE: a Python GUI for interactive phasor analysis of FLIM data
Apr 02, 2023
CRD: a De novo Design algorithm for prediction of Cognate Protein Receptors for small molecule ligands
Apr 02, 2023
Connectivity-based Meta-Bands: A new approach for automatic frequency band identification in connectivity analyses
Apr 02, 2023
PanGraphViewer: A Versatile Tool to Visualize Pangenome Graphs
Apr 02, 2023
Discovering motifs and genomic patterns with SMT: a high-performance data structure for counting kmers
Apr 02, 2023
PanKmer: k-mer based and reference-free pangenome analysis
Apr 02, 2023
Spatially Resolved Transcriptomics Mining in 3D and Virtual Reality Environments with VR-Omics
Apr 02, 2023
Clinical Phenotype Prediction From Single-cell RNA-seq Data using Attention-Based Neural Networks
Apr 02, 2023
Assessing Random Forest self-reproducibility for optimal short biomarker signature discovery
Apr 01, 2023
Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities
Apr 01, 2023
Retention time and fragmentation predictors increase confidence in variant peptide identification
Apr 01, 2023
Large-scale template-based structural modeling of T-cell receptors with known antigen specificity reveals complementarity features.
Apr 01, 2023
Stochastic modeling of a gene regulatory network driving B cell development in germinal centers
Apr 01, 2023
Model-based differential sequencing analysis
Apr 01, 2023
AutophagyNet: High-resolution data source for the analysis of autophagy and its regulation
Mar 30, 2023
Spatial Transcriptomics Analysis of Gene Expression Prediction using Exemplar Guided Graph Neural Network
Mar 30, 2023
Large-scale Annotation of Biochemically Relevant Pockets and Tunnels in Cognate Enzyme-Ligand Complexes
Mar 30, 2023
Sequencing accuracy and systematic errors in nanopore direct RNA sequencing
Mar 30, 2023
Modeling and predicting meat yield and growth performance using morphological features of narrow-clawed crayfish with machine learning techniques
Mar 29, 2023
simpleaf: A simple, flexible, and scalable framework for single-cell transcriptomics data processing using alevin-fry
Mar 29, 2023
Prediction of G4 formation in live cells with epigenetic data: a deep learning approach
Mar 29, 2023
3D Simulation of Tissue Mechanics with Cell Polarization
Mar 29, 2023
A meta-analysis of liver microbiome in beef and dairy cattle using metatranscriptome sequencing reads
Mar 29, 2023
KGETCDA: an efficient representation learning framework based on knowledge graph encoder from transformer for predicting circRNA-disease associations
Mar 29, 2023
Single-cell RNA-seq differential expression tests within a sample should use pseudo-bulk data of pseudo-replicates
Mar 29, 2023
Bayesian Multi-Study Non-Negative Matrix Factorization for Mutational Signatures
Mar 29, 2023
Machine learning-based gut microbiota pattern and response to fiber as a diagnostic tool for chronic inflammatory diseases
Mar 29, 2023
The impact of FASTQ and alignment read order on structural variation calling from long-read sequencing data
Mar 29, 2023
aPEAR: an R package for autonomous visualisation of pathway enrichment networks
Mar 29, 2023
Structural characterization of a novel luciferase-like-monooxygenase from Pseudomonas meliae an in silico approach
Mar 29, 2023
Scaling deep phylogenetic embedding to ultra-large reference trees: a tree-aware ensemble approach
Mar 29, 2023
Generating an Efficient Arginase Variant for Medical and Industrial Uses: in Silico Engineering
Mar 28, 2023
TemStaPro: protein thermostability prediction using sequence representations from protein language models
Mar 28, 2023
i-stLearn: An interactive platform for spatial transcriptomics analysis
Mar 28, 2023
Interpretable spatial cell learning enhances the characterization of patient tissue microenvironments with highly multiplexed imaging data
Mar 28, 2023
AI-Designed, Mutation-Resistant Broad Neutralizing Antibodies Against Multiple SARS-CoV-2 Strains
Mar 27, 2023
AnimalGAN: A Generative Adversarial Network Model Alternative to Animal Studies for Clinical Pathology Assessment
Mar 27, 2023
In-silico Screening of Origanum vulgare Phytocompounds as Potential Drug Agents Against Vp35 Protein of the Ebola Virus
Mar 27, 2023
IDSL.GOA: Gene Ontology Analysis for Metabolomics
Mar 27, 2023
De novo Genome Assembly, Functional Annotation and SSR Mining of Citrus reticulata (Kinnow) from Pakistan
Mar 27, 2023
Flattening the curve - How to get better results with small deep-mutational-scanning datasets
Mar 27, 2023
Small molecule machine learning: All models are wrong, some may not even be useful
Mar 27, 2023
Artificial Intelligence Boosted Molecular Dynamics
Mar 27, 2023
A novel method to accurately estimate pathway activity in single cells for clustering and differential analysis
Mar 27, 2023
exFINDER: identify external communication signals using single-cell transcriptomics data
Mar 27, 2023
Unravelling individual rhythmic abilities using machine learning
Mar 26, 2023
Clustering scRNA-seq data via qualitative and quantitative analysis
Mar 26, 2023
SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data
Mar 25, 2023
Somatic small-variant calling methods in Illumina DRAGEN™ Secondary Analysis
Mar 25, 2023
Virtual screening of antimicrobial plant extracts by machine-learning classification of chemical compounds in semantic space
Mar 25, 2023
A fast algorithm for 3D volume reconstruction from light field microscopy datasets
Mar 25, 2023
Modelling Emergence of Wolbachia Toxin-Antidote Protein Functions with an Evolutionary Algorithm.
Mar 25, 2023
MutationExplorer - a webserver for mutation of proteins and 3D visualization of energetic impacts
Mar 25, 2023
Investigating Open Reading Frames in Known and Novel Transcripts using ORFanage
Mar 25, 2023
Supervised learning of high-confidence phenotypic subpopulations from single-cell data
Mar 25, 2023
MIDAS: a fast and simple simulator for realistic microbiome data
Mar 25, 2023
xTrimoGene: An Efficient and Scalable Representation Learner for Single-Cell RNA-Seq Data
Mar 25, 2023
Mutafy: A webserver to identify high quality mutant protein structures in the Protein Data Bank
Mar 24, 2023
Global effects of identity and aging on the human sperm methylome
Mar 24, 2023
Dimension-agnostic and granularity-based spatially variable gene identification
Mar 24, 2023
Spotless: a reproducible pipeline for benchmarking cell type deconvolution in spatial transcriptomics
Mar 24, 2023
A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway
Mar 24, 2023
Distances and their visualization in studies of spatial-temporal genetic variation using single nucleotide polymorphisms (SNPs)
Mar 24, 2023
An explainable deep learning classifier of bovine mastitis based on whole genome sequence data - circumventing the p greater than greater than greater than n problem
Mar 24, 2023
Estimation of a treatment effect based on a modified covariates method with L0 norm
Mar 24, 2023
Integration of taxonomic signals from MAGs and contigs improves read annotation and taxonomic profiling of metagenomes
Mar 24, 2023
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Mar 24, 2023
Epitranscriptome analysis of NAD-capped RNA by spike-in-based normalization
Mar 24, 2023
JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations
Mar 24, 2023
Genetic structure and diversity of rfb locus of pathogenic species of genus Leptospira
Mar 24, 2023
Capturing Spatiotemporal Signaling Patterns in Cellular Data with Geometric Scattering Trajectory Homology
Mar 24, 2023
Uncovering Hidden Cancer Self-Dependencies through Analysis of shRNA-Level Dependency Scores
Mar 24, 2023
LOCATOR: feature extraction and spatial analysis of the cancer tissue microenvironment using mass cytometry imaging technologies
Mar 24, 2023
Ensemble-GNN: federated ensemble learning with graph neural networks for disease module discovery and classification
Mar 24, 2023
An integrative framework for circular RNA quantitative trait locus discovery with application in human T cells
Mar 24, 2023
A meta-analysis of immune cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes
Mar 23, 2023
Accurate Flow Decomposition via Robust Integer Linear Programming
Mar 23, 2023
SpaceWalker: Interactive Gradient Exploration for Spatial Transcriptomics Data
Mar 23, 2023
Deep learning for rapid analysis of cell divisions in vivo during epithelial morphogenesis and repair
Mar 23, 2023
Multi-Omics Integration For Disease Prediction Via Multi-Level Graph Attention Network And Adaptive Fusion
Mar 23, 2023
An Ensemble Learning Approach to perform Link Prediction on Large Scale Biomedical Knowledge Graphs for Drug Repurposing and Discovery
Mar 23, 2023
escheR: Unified multi-dimensional visualizations with Gestalt principles
Mar 23, 2023
Artificial selection footprints in domestic chicken genomes
Mar 23, 2023
FLONE: fully Lorentz network embedding for inferring novel drug targets
Mar 23, 2023
HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes
Mar 23, 2023
READRetro: Natural Product Biosynthesis Planning with Retrieval-Augmented Dual-View Retrosynthesis
Mar 23, 2023
Inference of single cell profiles from histology stains with the Single-Cell omics from Histology Analysis Framework (SCHAF)
Mar 23, 2023
Flexible parsing and preprocessing of technical sequences with splitcode
Mar 23, 2023
DRPBind: prediction of DNA, RNA and protein binding residues in intrinsically disordered protein sequences
Mar 23, 2023
RExPRT: a machine learning tool to predict pathogenicity of tandem repeat loci
Mar 23, 2023
MetaLLM: Residue-wise Metal ion Prediction UsingDeep Transformer Model
Mar 23, 2023
Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment
Mar 22, 2023
High performance Legionella pneumophila source attribution using genomics-based machine learning classification
Mar 22, 2023
NOMAD2 provides ultra-efficient, scalable, and unsupervised discovery on raw sequencing reads
Mar 21, 2023
aenmd: Annotating escape from nonsense-mediated decay for transcripts with protein-truncating variants
Mar 21, 2023
PAPET: a collection of performant algorithms to identify 5-methyl cytosine from PacBio SequelII data
Mar 21, 2023
A Video Segmentation Pipeline for Assessing changes in Pupil Response to Light After Cannabis Consumption
Mar 21, 2023
Long read proteogenomics to connect disease-associated sQTLs to the protein isoform effectors of disease
Mar 21, 2023
PGAR-Zernike: an ultra-fast, accurate and fully open-sourcestructure retrieval toolkit for convenient structural database construction
Mar 21, 2023
Identification of annotation artifacts concerning the CHALCONE SYNTHASE (CHS)
Mar 21, 2023
S3-CIMA: Supervised spatial single-cell image analysis for the identification of disease-associated cell type compositions in tissue
Mar 21, 2023
AB-Gen: Antibody Library Design with Generative Pre-trained Transformer and Deep Reinforcement Learning
Mar 21, 2023
A machine-readable specification for genomics assays
Mar 21, 2023
Statistical modeling and analysis of multiplexed imaging data
Mar 21, 2023
DeepBindGCN: Integrating Molecular Vector Representation with Graph Convolutional Neural Networks for Accurate Protein-Ligand Interaction Prediction
Mar 20, 2023
Accurate prediction of transcriptional activity of single missense variants in HIV Tat with deep learning
Mar 20, 2023
VariPred: Enhancing Pathogenicity Prediction of Missense Variants Using Protein Language Models
Mar 20, 2023
How far are we from personalized gene expression prediction using sequence-to-expression deep neural networks?
Mar 20, 2023
mosna reveals different types of cellular interactionspredictive of response to immunotherapies in cancer
Mar 20, 2023
ALaSCA: A novel in silico simulation platform to untangle biological pathway mechanisms, with a case study in Type 1 Diabetes progression
Mar 20, 2023
An interpretable, finite sample valid alternative to Pearson's X2 for scientific discovery
Mar 20, 2023
ITNR: Inversion Transformer-based Neural Ranking for Cancer Drug Recommendations
Mar 20, 2023
Rigid Scaffolds are Promising for Designing Macrocyclic Kinase Inhibitors
Mar 20, 2023
On quantum computing and geometry optimization
Mar 20, 2023
PhyloSophos: a high-throughput scientific name mapping algorithm augmented with explicit consideration of taxonomic science
Mar 20, 2023
Identification of selective sweeps in bacteria
Mar 19, 2023
compare_genomes: a comparative genomics workflow to streamline the analysis of evolutionary divergence across genomes
Mar 17, 2023
Magnipore: Prediction of differential single nucleotide changes in the Oxford Nanopore Technologies sequencing signal of SARS-CoV-2 samples
Mar 17, 2023
Standardizing and applying a mating-based whole-genome simulation approach reveals caution in using chromosome-level PCA and kinship estimates
Mar 16, 2023
Guiding the design of well-powered Hi-C experiments to detect differential loops
Mar 16, 2023
3DMolMS: Prediction of Tandem Mass Spectra from Three Dimensional Molecular Conformations
Mar 16, 2023
Accurate estimation of rare cell type fractions fromtissue omics data via hierarchical deconvolution
Mar 16, 2023
Uncovering the Hidden Gems of Psoriasis Literature: An Neural Language Model-Assisted Interactive Web Tool
Mar 16, 2023
NanoSquiggleVar: A method for direct analysis of targeted variants based on nanopore sequencing signals
Mar 16, 2023
Multiple sequence-alignment-based RNA language model and its application to structural inference
Mar 16, 2023
SafeMut: UMI-aware variant simulator incorporating allele-fraction overdispersion in read editing
Mar 15, 2023
SpatialScope: A unified approach for integrating spatial and single-cell transcriptomics data using deep generative models
Mar 15, 2023
Improved integration of single cell transcriptome data demonstrated on heart failure in mice and men
Mar 15, 2023
Library size confounds biology in spatial transcriptomics data
Mar 15, 2023
LEP-AD: Language Embedding of Proteins and Attention to Drugs predicts drug target interactions
Mar 15, 2023
Fast Approximate IsoRank for Scalable Global Alignment of Biological Networks
Mar 15, 2023
ChemEM: flexible docking of small molecules in Cryo-EM structures using difference maps
Mar 15, 2023
How much storage precision can be lost: Guidance for near-lossless compression of untargeted metabolomics mass spectrometry data
Mar 15, 2023
GenoPipe: identifying the genotype of origin within (epi)genomic datasets
Mar 15, 2023
BioConvert: a comprehensive format converter for life sciences
Mar 15, 2023
What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds
Mar 15, 2023
Development of QSAR Models to Identify Mycobacterium tuberculosis enoyl-ACP-reductase Enzyme Inhibitors
Mar 15, 2023
Testing nonparametrically for dependence between nonstationary time series with very few replicates
Mar 14, 2023
Spatially aware self-representation learning for tissue structure characterization and spatial functional genes identification
Mar 14, 2023
BQsupports: systematic assessment of the support and novelty of new biomedical associations
Mar 14, 2023
Analysis of RNA processing directly from spatial transcriptomics data reveals previously unknown regulation
Mar 14, 2023
InClust+: the multimodal version of inClust for multimodal data integration, imputation, and cross modal generation
Mar 14, 2023
The landscape of cancer rewired GPCR signaling axes
Mar 14, 2023
GeneTuring tests GPT models in genomics
Mar 13, 2023
Spectral detection of condition-specific biological pathways in single-cell gene expression data
Mar 13, 2023
eOmics: an R package for improved omics data analysis
Mar 13, 2023
PandoraRLO: DQN and Graph convolution based method for optimized ligand pose
Mar 13, 2023
An interpretable ML model to characterize patient-specific HLA-I antigen presentation
Mar 13, 2023
Improvements in the detection power of algorithms for analyzing next-generation sequencing based bulked segregant analysis data via estimating thresholds at the genomic region level
Mar 13, 2023
E2EGraph: An End-to-end Graph Learning Model for Interpretable Prediction of Pathlogical Stages in Prostate Cancer
Mar 12, 2023
Constraint-based modelling predicts metabolic signatures of low- and high-grade serous ovarian cancer
Mar 12, 2023
Impact and characterization of serial structural variations across humans and great apes
Mar 12, 2023
An efficient error correction and accurate assembly tool for noisy long reads
Mar 12, 2023
vcfdist: Accurately benchmarking phased small variant calls in human genomes
Mar 12, 2023
ZygosityPredictor
Mar 12, 2023
STdGCN: accurate cell-type deconvolution using graph convolutional networks in spatial transcriptomic data
Mar 12, 2023
Superposition of target structures enables design of bi-stable RNA molecules with deep learning
Mar 12, 2023
plasma: Partial LeAst Squares for Multiomics Analysis
Mar 12, 2023
Panpipes: a pipeline for multiomic single-cell data analysis.
Mar 12, 2023
The GlycoPaSER prototype as a real-time N-glycopeptide identification tool based on the PaSER parallel computing platform
Mar 12, 2023
Addressing Erroneous Scale Assumptions in Microbe and Gene Set Enrichment Analysis
Mar 12, 2023
Machine Learning to Identify Molecular Markers for Metabolic Disease Development Using Mouse Models
Mar 12, 2023
Proformer: a hybrid macaron transformer model predicts expression values from promoter sequences
Mar 12, 2023
Data-Driven Mathematical Approach for Removing Rare Features in Zero-Inflated Datasets
Mar 12, 2023
In-silico Discovery of Genetic Diversity in Cucumis sativus var. hardwickii: A Wild Relative of Cultivated Cucumber
Mar 12, 2023
Computational investigation of Scutellarein derivatives as an inhibitor against triple-negative breast cancer by Quantum calculation, and drug-designed approaches
Mar 08, 2023
Identification of mobile element insertion from whole genome sequencing data using deep neural network model
Mar 08, 2023
Prediction of protein assemblies by structure sampling followed by interface-focused scoring
Mar 08, 2023
Empowering Beginners in Bioinformatics with ChatGPT
Mar 08, 2023
Unraveling the Interactions between Human DPP4 Receptor, SARS-CoV-2 Variants, and MERS-CoV, converged for Pulmonary Disorders Integrating through Immunoinformatics and Molecular Dynamics
Mar 07, 2023
QuaC: A Pipeline Implementing Quality Control Best Practices for Genome Sequencing and Exome Sequencing Data
Mar 07, 2023
Quantum algorithm for position weight matrix matching
Mar 07, 2023
ELITE: Expression deconvoLution using lInear optimizaTion in bulk transcriptomics mixturEs
Mar 07, 2023
Morphine Re-arranges Chromatin Spatial Architecture of Primate Cortical Neurons
Mar 07, 2023
Application of fuzzy measures to move towards the cyber-taxonomy
Mar 07, 2023
Matrix and analysis metadata standards (MAMS) to facilitate harmonization and reproducibility of single-cell data
Mar 07, 2023
A bootstrap model comparison test for identifying genes with context-specific patterns of genetic regulation
Mar 07, 2023
SAKit: an all-in-one analysis pipeline for identifying novel protein caused by variant events at genomic and transcriptic level
Mar 07, 2023
Analysis of multi-condition single-cell data with latent embedding multivariate regression
Mar 07, 2023
optimalTAD: annotation of topologically associating domains based on chromatin marks enrichment
Mar 07, 2023
Modelling capture efficiency of single cell RNA-sequencing data improves inference of transcriptome-wide burst kinetics
Mar 07, 2023
You can move, but you can't hide: identification of mobile genetic elements with geNomad
Mar 06, 2023
Computational modeling and optimization of biofabrication in Tissue Engineering and Regenerative Medicine -- a literature review
Mar 06, 2023
PromoR and PromoS for E. coli promoter recognition and classification
Mar 06, 2023
Biological representation disentanglement of single-cell data
Mar 06, 2023
Cellos: High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology
Mar 06, 2023
Quantifying tumor specificity using Bayesian probabilistic modeling for drug target discovery and prioritization
Mar 06, 2023
LSTrAP-denovo: Automated Generation of Transcriptome Atlases for Eukaryotic Species Without Genomes
Mar 06, 2023
Novel crAssphage isolates exhibit conserved gene order and purifying selection of the host specificity protein
Mar 06, 2023
GPU-accelerated Dynamic Time Warping for SelectiveNanopore Sequencing
Mar 06, 2023
PAE Viewer: A webserver for the interactive visualization of the predicted aligned error for multimer structure predictions and crosslinks
Mar 06, 2023
Extraction of biological signals by factorization enables the reliable analysis of single-cell transcriptomics
Mar 04, 2023
JAMS - A framework for the taxonomic and functional exploration of microbiological genomic data
Mar 04, 2023
Underlying causes for prevalent false positives and false negatives in STARR-seq data
Mar 03, 2023
Feature selection followed by a residuals-based normalization simplifies and improves single-cell gene expression analysis
Mar 03, 2023
An econometric lens resolves cell-state parallax
Mar 03, 2023
Identifying promoter sequence architectures via a chunking-based algorithm using non-negative matrix factorisation
Mar 03, 2023
Decoding Duchenne muscular dystrophy transcriptome to single nuclei level reveals clinical-genetic correlations
Mar 03, 2023
Fast and accurate DNASeq Variant Calling workflow composed of LUSH toolkit
Mar 02, 2023
Integrating weighted correlation network analysis and machine learning identifies common trajectories of prostate cancer
Mar 02, 2023
Gene essentiality in cancer is better predicted by mRNA abundance than by gene regulatory network-inferred activity
Mar 02, 2023
Molecular Adverse Outcome Pathways: towards the implementation of transcriptomics data in risk assessments
Mar 02, 2023
NMRQNet: a deep learning approach for automatic identification and quantification of metabolites using Nuclear Magnetic Resonance (NMR) in human plasma samples
Mar 02, 2023
Automatic Detection of Cell-cycle Stages using Recurrent Neural Networks
Mar 01, 2023
Evaluating Prompt Tuning for Conditional Protein Sequence Generation
Mar 01, 2023
PS4: a Next-Generation Dataset for Protein SingleSequence Secondary Structure Prediction
Mar 01, 2023
Rotamer Density Estimator is an Unsupervised Learner of the Effect of Mutations on Protein-Protein Interaction
Mar 01, 2023
StereoCell enables high accuracy single cell segmentation for spatial transcriptomic dataset
Mar 01, 2023
Triggering blood-lipid-profile by immunomodulatory and antimicrobial molecules for cross-evaluation of early detection of cancer
Mar 01, 2023
pyCapsid: Identifying dominant dynamics and quasi-rigid mechanical units in protein shells
Mar 01, 2023
Estimating the vertical ionization potential of single-stranded DNA molecules
Mar 01, 2023
ClockBase: a comprehensive platform for biological age profiling in human and mouse
Mar 01, 2023
Predicting CRISPR-Cas12a guide efficiency for targeting using Machine Learning
Mar 01, 2023
A data-efficient deep learning tool for scRNA-Seq label transfer in neuroscience
Mar 01, 2023
MEDIPIPE: an automated and comprehensive pipeline for cfMeDIP-seq data quality control and analysis
Mar 01, 2023
Directing Protein Design Choices by Per-Residue Energy Breakdown Analysis with an Interactive Web Application
Feb 28, 2023
Robustness of Felsenstein's versus Transfer Bootstrap Supports with respect to Taxon Sampling
Feb 28, 2023
A data-fusion approach to identifying developmental dyslexia from multi-omics datasets
Feb 28, 2023
Application of a Machine Learning Approach Towards the Targeted Identification of Phage Depolymerases
Feb 28, 2023
Automated quantification of lipophagy in Saccharomyces cerevisiae from fluorescence and cryo-soft X-ray microscopy data using deep learning
Feb 27, 2023
Protein embeddings improve phage-host interaction prediction
Feb 27, 2023
Repurposing of Anti-infectives for the Management of Onchocerciasis using Machine Learning and Protein Docking Studies
Feb 27, 2023
InjectionDesign: Plate Design with Optimized Stratified Block Randomization for Modern LC/GC-MS-Based Sample Preparation
Feb 27, 2023
Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of cancer
Feb 27, 2023
Bactabolize: A tool for high-throughput generation of bacterial strain-specific metabolic models
Feb 27, 2023
An associative transcriptomics study on rice bean (Vigna umbellata) provides new insights into genetic basis and candidate genes governing flowering, maturity and seed weight
Feb 27, 2023
A global test of hybrid ancestry fromgenome-scale data
Feb 27, 2023
MsPBRsP: Multi-scale Protein Binding Residues Prediction Using Language Model
Feb 27, 2023
Influence of Demographic, Socio-economic, and Brain Structural Factors on Adolescent Neurocognition: A Correlation Analysis in the ABCD Initiative
Feb 27, 2023
EnCPdock: a web-interface for direct conjoint comparative analyses of complementarity and binding energetics in inter-protein associations
Feb 27, 2023
Advanced tensor decomposition-based integrated analysis of protein-protein interaction with cancer gene expression can improve coincidence with clinical labels
Feb 27, 2023
Microsnoop: a generalist tool for the unbiased representation of heterogeneous microscopy images
Feb 27, 2023
MDTOMO: Continuous conformational variability analysis in cryo electron subtomogram data using flexible fitting based on Molecular Dynamics simulations
Feb 27, 2023
PIFiA: Self-supervised Approach for Protein Functional Annotation from Single-Cell Imaging Data
Feb 27, 2023
Pan-cancer genetic analysis of disulfidptosis-related gene set
Feb 27, 2023
Cellograph: A Semi-supervised Approach to Analyzing Multi-condition Single-cell RNA-sequencing Data Using Graph Neural Networks
Feb 27, 2023
Benchmarking differential abundance methods for finding condition-specific prototypical cells in multi-sample single-cell datasets
Feb 27, 2023
A robust model for cell type-specific interindividual variation in single-cell RNA sequencing data
Feb 27, 2023
Adversarial and variational autoencoders improve metagenomic binning
Feb 27, 2023
Centrifuge+: improving metagenomic analysis upon Centrifuge
Feb 27, 2023
A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets
Feb 26, 2023
Elucidation of Genome-wide Understudied Proteins targeted by PROTAC-induced degradation using Interpretable Machine Learning
Feb 24, 2023
GENEvaRX: A Novel AI-Driven Method and Web Tool Can Identify Critical Genes and Effective Drugs for Lichen Planus
Feb 24, 2023
Single cell and spatial alternative splicing analysis with long read sequencing
Feb 24, 2023
SEG: Segmentation Evaluation in absence of Ground truth labels
Feb 24, 2023
PhageDPO: Phage Depolymerase Finder
Feb 24, 2023
Themisto: a scalable colored k-mer index for sensitive pseudoalignment against hundreds of thousands of bacterial genomes
Feb 24, 2023
Predicting S. aureus antimicrobial resistance with interpretable genomic space maps
Feb 24, 2023
Ensemble deep learning of embeddings for clustering multimodal single-cell omics data
Feb 23, 2023
Retrieved Sequence Augmentation for Protein Representation Learning
Feb 23, 2023
Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries
Feb 23, 2023
A mechanistic simulation of molecular cell states over time
Feb 23, 2023
Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole slide imaging with accurate single-cell segmentation
Feb 23, 2023
Genetic dependencies associated with transcription factor activities in human cancer cell lines
Feb 23, 2023
Utilizing Pre-trained Network Medicine Models for Generating Biomarkers, Targets, Re-purposing Drugs, and Personalized Therapeutic Regimes: COVID-19 Applications
Feb 22, 2023
CryoPPP: A Large Expert-Labelled Cryo-EM Image Dataset for Machine Learning Protein Particle Picking
Feb 22, 2023
choros: correction of sequence-based biases for accurate quantification of ribosome profiling data
Feb 22, 2023
Phased nanopore assembly with Shasta and modular graph phasing with GFAse
Feb 22, 2023
Reconstruction of TrkB complex assemblies and localizing an-tidepressant targets using Artificial Intelligence
Feb 22, 2023
Flame (v2.0): advanced integration and interpretation of functional enrichment results from multiple sources
Feb 22, 2023
Investigating racial disparities in carcinomas through TCGA transcriptomic and proteomic database
Feb 22, 2023
Dimensionality reduction methods for extracting functional networks from large-scale CRISPR screens
Feb 22, 2023
SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra
Feb 22, 2023
DR-BERT: A Protein Language Model to Annotate Disordered Regions
Feb 22, 2023
Fast Identification of Optimal Monotonic Classifiers
Feb 22, 2023
Identification of novel prognostic targets in coronary artery disease and related complications using bioinformatics and next generation sequencing data analysis
Feb 22, 2023
Europe PMC Annotated Full-text Corpus for Gene/Proteins, Diseases and Organisms
Feb 21, 2023
PANGEA: A New Gene Set Enrichment Tool for Drosophila and Common Research Organisms
Feb 21, 2023
LISTER: Semi-automatic metadata extraction from annotated experiment documentation in eLabFTW
Feb 21, 2023
Integrated analysis and annotation for T-cell receptor sequences using TCRosetta
Feb 21, 2023
Dual-wield NTPase: a novel protein family mined from AlphaFold DB
Feb 21, 2023
S1000: A better taxonomic name corpus for biomedical information extraction
Feb 21, 2023
DeepHeme: A generalizable, bone marrow classifierwith hematopathologist-level performance
Feb 21, 2023
Updating TCGA glioma classification through integration of molecular profiling data following the 2016 and 2021 WHO guidelines
Feb 21, 2023
Comprehensive codon usage analyses of the mutations in the Parkin protein leading to Parkinsonism
Feb 21, 2023
Merizo: A rapid and accurate domain segmentation method using invariant point attention
Feb 21, 2023
Structome: Exploring the structural neighbourhood of proteins
Feb 21, 2023
NTpred: A robust and precise machine learningframework for in-silico identification of Tyrosine nitration sites in protein sequences
Feb 21, 2023
Interpreting biologically informed neural networks for enhanced biomarker discovery and pathway analysis
Feb 21, 2023
A Simple Way to Incorporate Target Structural Information in Molecular Generative Models
Feb 21, 2023
OME-Zarr: a cloud-optimized bioimaging file format with international community support
Feb 21, 2023
Active mesh and neural network pipeline for cell aggregate segmentation
Feb 21, 2023
An integrated bioinformatics approach to identify candidate biomarkers and the evaluation of drugs for pheochromocytoma
Feb 21, 2023
OPTIMAL: An OPTimsed Imaging Mass cytometry AnaLysis framework for Segmentation and Data Exploration
Feb 21, 2023
Audit to Forget: A Unified Method to Revoke Patients' Private Data in Intelligent Healthcare
Feb 21, 2023
Cardinal v3 - a versatile open source software for mass spectrometry imaging analysis
Feb 21, 2023
A robust Platform for Integrative Spatial Multi-omics Analysis to Map Immune Responses to SARS-CoV-2 infection in Lung Tissues
Feb 20, 2023
Tracking and curating putative SARS-CoV-2 recombinants with RIVET
Feb 19, 2023
Accurate label-free quantification by directLFQ to compare unlimited numbers of proteomes
Feb 19, 2023
TRGdb: a universal resource for exploration of taxonomically restricted genes in bacteria
Feb 18, 2023
Computational prediction of human deep intronic variation
Feb 17, 2023
BinderSpace: A Package for Sequence Space Analyses for Datasets of Affinity-Selected Oligonucleotides and Peptide-Based Molecules
Feb 16, 2023
Toxoplasma gondii aspartic protease 5 (TgASP5): Understanding structural details and inhibition mechanism.
Feb 16, 2023
Virotest: a bioinformatics pipeline for virus identification in plants.
Feb 16, 2023
An attention network for predicting T cell receptor-peptide binding can associate attention with interpretable protein structural properties
Feb 16, 2023
BORD: A Biomedical Ontology based method for concept Recognition using Distant supervision: Application to Phenotypes and Diseases
Feb 16, 2023
Clustering rare diseases within an ontology-enriched knowledge graph
Feb 16, 2023
μ-PBWT: Enabling the Storage and Use of UK Biobank Data on a Commodity Laptop
Feb 16, 2023
Precise and ultrafast tandem repeat variant detection in massively parallel sequencing reads
Feb 16, 2023
Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Sishenwan in the Treatment of diabetic nephropathy
Feb 16, 2023
Benchmarking the Autoencoder Design for Imputing Single-Cell RNA Sequencing Data
Feb 16, 2023
Rational Prediction of PROTAC-compatible Protein-Protein Interfaces by Molecular Docking
Feb 16, 2023
Prediction and Design of Protease Enzyme Specificity Using a Structure-Aware Graph Convolutional Network
Feb 16, 2023
Automatic identification of scientific publications describing digital reconstructions of neural morphology
Feb 15, 2023
PIQLE: protein-protein interface quality estimation by deep graph learning of multimeric interaction geometries
Feb 15, 2023
A computational investigation on Rho-related GTP-binding protein RhoB through molecular modeling and molecular dynamics simulation study
Feb 15, 2023
BLINK: Ultrafast tandem mass spectrometry cosine similarity scoring
Feb 15, 2023
Uni-Fold MuSSe: De Novo Protein Complex Prediction with Protein Language Models
Feb 15, 2023
Classification of dog breeds using convolutional neural network models and support vector machine
Feb 15, 2023
Artificial Intelligence uncovers Evolutionarily Conserved Intracellular Allosteric Modulators of GPCR-Gα interface.
Feb 15, 2023
Multivariate Residualization in Medical Imaging Analysis
Feb 15, 2023
JUMP: statistical analysis of replicability across two studies
Feb 15, 2023
A Systematic Benchmark of Machine Learning Methods for Protein-RNA Interaction Prediction
Feb 15, 2023
SynEcoSys: a multifunctional platform of large-scale single-cell omics data analysis
Feb 15, 2023
Orthogonal outlier detection and dimension estimation for improved MDS embedding of biological datasets
Feb 15, 2023
DeepTAP: an RNN-based method of TAP-binding peptide prediction in the selection of tumor neoantigens
Feb 15, 2023
CellWalker: A user-friendly and modular computational pipeline for morphological analysis of microscopy images
Feb 15, 2023
Pairtools: from sequencing data to chromosome contacts
Feb 15, 2023
The HRA Organ Gallery Affords Immersive Superpowers for Building and Exploring the Human Reference Atlas with Virtual Reality
Feb 15, 2023
Vulture: Cloud-enabled scalable mining of microbial reads in public scRNA-seq data
Feb 15, 2023
NeoTCR: an immunoinformatic database of experimentally-supported functional neoantigen-specific TCR sequences
Feb 15, 2023
kakapo: Easy extraction and annotation of genes from raw RNA-seq reads
Feb 15, 2023
Single-cell transcriptomic analysis of mouse liver reveals nonparenchymal cells' intricate responses to PCB126 exposure
Feb 15, 2023
Pervasive, conserved secondary structure in highly charged protein regions
Feb 15, 2023
Genome-wide identification and characterization of major RNAi genes highlighting their regulatory factors in Cowpea (Vigna unguiculata (L.) Walp.)
Feb 15, 2023
Systematic analysis of disease-linked rare germline variants reveals new classes of cancer predisposing genes
Feb 15, 2023
NetSyn: genomic context exploration of protein families
Feb 15, 2023
Optimizing Xenium In Situ data utility by quality assessment and best practice analysis workflows
Feb 14, 2023
Cell type-specific Interaction Analysis using Doublets in scRNA-seq (CIcADA)
Feb 14, 2023
simCAS: an embedding-based method for simulating single-cell chromatin accessibility sequencing data
Feb 14, 2023
From Cell-Lines to Cancer Patients: Personalized Drug Synergy Prediction
Feb 14, 2023
A comparison of bioinformatics pipelines for compositional analysis of the human gut microbiome
Feb 14, 2023
Improved in situ Characterization of Proteome-wide Protein Complex Dynamics with Thermal Proximity Co-Aggregation
Feb 14, 2023
Gene-signatures for early detection of cancers
Feb 13, 2023
Olivar: fully automated and variant aware primer design for multiplex tiled amplicon sequencing of pathogen genomes
Feb 13, 2023
Petagraph: A large-scale unifying knowledge graph framework for integrating biomolecular and biomedical data
Feb 13, 2023
LEA: Latent Eigenvalue Analysis in application to high-throughput phenotypic profiling
Feb 13, 2023
Streamline unsupervised machine learning to survey and graph indel-based haplotypes from pan-genomes
Feb 13, 2023
Drug repurposing for Leishmaniasis with Hyperbolic Graph Neural Networks
Feb 13, 2023
Reply to: Caution Regarding the Specificities of Pan-Cancer Microbial Structure
Feb 13, 2023
Insight on physicochemical properties governing peptide MS1 response in HPLC-ESI-MS/MS proteomics: A deep learning approach
Feb 13, 2023
SeqScreen-Nano: a computational platform for rapid, in-field characterization of previously unseen pathogens.
Feb 13, 2023
Unraveling Spatial Gene Associations with SEAGAL: a Python Package for Spatial Transcriptomics Data Analysis and Visualization
Feb 13, 2023
Foreign RNA spike-ins enable accurate allele-specific expression analysis at scale
Feb 12, 2023
Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques.
Feb 11, 2023
Protein Fitness Prediction is Impacted by the Interplay of Language Models, Ensemble Learning, and Sampling Methods
Feb 10, 2023
Prioritizing Complex Disease Genes from Heterogeneous Public Databases
Feb 10, 2023
PopTradeOff: a database for exploring population-specific trade-offs between adaptive evolution, disease susceptibility, and drug responsiveness
Feb 10, 2023
TidyGEO: Preparing analysis-ready datasets from Gene Expression Omnibus
Feb 10, 2023
IDSL.CSA: Composite Spectra Analysis for Chemical Annotation of Untargeted Metabolomics Datasets
Feb 10, 2023
Benchmarking Variational AutoEncoders on cancer transcriptomics data
Feb 10, 2023
ImmuneMirror: a Machine Learning-based Integrative Pipeline and Web Server for Neoantigen Prediction
Feb 10, 2023
Metaphor - A workflow for streamlined assembly and binning of metagenomes
Feb 10, 2023
Exploring the Knowledge of An Outstanding Protein to Protein Interaction Transformer
Feb 10, 2023
DRomics, a workflow to model and make sense of dose-response (multi-)omics data in (eco)toxicology
Feb 10, 2023
GENIUS: GEnome traNsformatIon and spatial representation of mUltiomicS data
Feb 10, 2023
An algorithm that combines machine learning ensemble modeling and network analysis to predict self-tolerant tumor-associated antigens for anti-cancer immunotherapy
Feb 10, 2023
HMMSTRTM: A hidden Markov model for local structure prediction in globular and membrane associated proteins
Feb 10, 2023
Unipept Desktop 2.0: construction of targeted reference protein databases for proteogenomics analyses
Feb 10, 2023
Adaptive Digital Tissue Deconvolution
Feb 10, 2023
Pharmacodynamic model of PARP1 inhibition and global sensitivity analyses can lead to cancer biomarker discovery
Feb 10, 2023
BioNAR: An Integrated Biological Network Analysis Package in Bioconductor
Feb 10, 2023
CAGECAT: The CompArative GEne Cluster Analysis Toolbox for rapid search and visualisation of homologous gene clusters
Feb 10, 2023
Identifying Mutational Hotspots using Differences in Atomic Fluctuations combined with Positional Variability
Feb 09, 2023
Does joint impedance improve dynamic leg simulations with explicit and implicit solvers?
Feb 09, 2023
Impact of experimental bias on compositional analysis of microbiome data
Feb 09, 2023
Proteome-wide comparison of tertiary protein structures reveal extensive molecular mimicry in Plasmodium-human interactions
Feb 09, 2023
Structural and functional classification of G-quadruplex families within the human genome
Feb 09, 2023
Spanve: an Effective Statistical Method to Detect Spatially Variable Genes in Large-scale Spatial Transcriptomics Data
Feb 08, 2023
Probabilistic cell/domain-type assignment of spatial transcriptomics data with SpatialAnno
Feb 08, 2023
GeneDART: Extending gene coverage in image-based spatial transcriptomics by deep learning-based domain adaptation with barcode-based RNA-sequencing data
Feb 08, 2023
Automatic quality control of single-cell and single-nucleus RNA-seq using valiDrops
Feb 08, 2023
Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease
Feb 08, 2023
aweMAGs: a fully automated workflow for quality assessment and annotation of eukaryotic genomes from metagenomes
Feb 08, 2023
CircSSNN: circRNA-binding site prediction via sequence self-attention neural networks with pre-normalization
Feb 07, 2023
Heuristics for the De Bruijn Graph Sequence Mapping Problem
Feb 07, 2023
Gaussian Mixture Modeling Extensions for Improved False Discovery Rate Estimation in GC-MS Metabolomics
Feb 07, 2023
IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods
Feb 07, 2023
Accelerated nanopore basecalling with SLOW5 data format
Feb 07, 2023
Transcriptional profile of ribosome-associated quality control components and their associated phenotypes in mammalian cells
Feb 07, 2023
Clustering-independent estimation of cell abundances in bulk tissues using single-cell RNA-seq data
Feb 07, 2023
BiGPICC: a graph-based approach to identifying carcinogenic gene combinations from mutation data
Feb 07, 2023
Machine learning models for the prediction of enzyme properties should be tested on proteins not used for model training
Feb 07, 2023
xTrimoDock: Rigid Protein Docking via Cross-Modal Representation Learning and Spectral Algorithm
Feb 06, 2023
Taxonomical and ontological analysis of verified natural and laboratory human coronavirus hosts
Feb 06, 2023
Helixer--de novo Prediction of Primary Eukaryotic Gene Models Combining Deep Learning and a Hidden Markov Model.
Feb 06, 2023
Network-based molecular subtyping of acral melanoma
Feb 05, 2023
FarmGTEx TWAS-server: an interactive web server for customized TWAS analysis in both human and farm animals
Feb 05, 2023
MpoxRadar: a worldwide Mpox genomic surveillance dashboard
Feb 05, 2023
SoyOmics: A deeply integrated database on soybean multi omics
Feb 05, 2023
IQMMA: an efficient MS1 intensity extraction using multiple feature detection algorithms for DDA proteomics
Feb 04, 2023
Systematic Analysis of KRAS-ligand Interaction Modes and Flexibilities Reveals the Binding Characteristics
Feb 04, 2023
Gene panel selection for targeted spatial transcriptomics
Feb 04, 2023
Protein Sequence Design by Entropy-based Iterative Refinement
Feb 04, 2023
Correspondence between functional scores from deep mutational scans and predicted effects on protein stability
Feb 04, 2023
SIN3 gene regulatory activity is linked to RNA polymerase II pausing
Feb 04, 2023
Mammalian Milk Glycomes: Connecting the Dots between Evolutionary Conservation and Biosynthetic Pathways
Feb 04, 2023
Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator
Feb 04, 2023
IMPACT: a web server for exploring immunotherapeutic predictive and cancer prognostic biomarkers
Feb 03, 2023
A hybrid method for discovering interferon-gamma inducing peptides in human and mouse
Feb 03, 2023
SHARE-Topic: Bayesian Inerpretable Modelling of Single-Cell Multi-Omic Data
Feb 03, 2023
Towards Universal Cell Embeddings: Integrating Single-cell RNA-seq Datasets across Species with SATURN
Feb 03, 2023
LimoRhyde2: genomic analysis of biological rhythms based on effect sizes
Feb 03, 2023
Label-free tumor cells classification using deep learning and high-content imaging
Feb 03, 2023
Structure-informed Language Models Are Protein Designers
Feb 03, 2023
Construction of a 3D whole organism spatial atlas by joint modeling of multiple slices
Feb 03, 2023
Omicron's Intrinsic Gene-Gene Interactions Jumped Away from Earlier SARS-CoV-2 Variants and Gene Homologs between Humans and Animals
Feb 03, 2023
Paired single-cell multi-omics data integration with Mowgli
Feb 03, 2023
Novel integrated computational AMP discovery approaches highlight diversity in the helminth AMP repertoire
Feb 03, 2023
DandD: efficient measurement of sequence growth and similarity
Feb 03, 2023
Masked superstrings as a unified framework for textual ????-mer set representations
Feb 03, 2023
Finding phylogeny-aware and biologically meaningful averages of metagenomic samples: L2UniFrac
Feb 03, 2023
Data-driven filtering for denoising of TCRpMHC single-cell data: a benchmark
Feb 03, 2023
Development of attention-based robust deep learning model for tongue diagnosis by smartphone
Feb 03, 2023
Integrating AlphaFold and deep learning for atomistic interpretation of cryo-EM maps
Feb 03, 2023
sciCSR infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data
Feb 03, 2023
Bioinformatic identification of ClpI, a distinct class of Clp unfoldases in Actinomycetota
Feb 03, 2023
The local topology of dynamical network models for biology
Feb 03, 2023
The Master Database of All Possible RNA Sequences and Its Integration with RNAcmap for RNA Homology Search
Feb 03, 2023
Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data
Feb 03, 2023
Construction of a searchable database for gene expression changes in spinal cord injury experiments
Feb 03, 2023
Hmrbase2: A comprehensive database of hormones and their receptors
Feb 03, 2023
PlasmidHunter: Accurate and fast prediction of plasmid sequences using gene content profile and machine learning
Feb 03, 2023
PLANET: A Multi-Objective Graph Neural Network Model for Protein-Ligand Binding Affinity Prediction
Feb 03, 2023
Proteome encoded determinants of protein sorting into extracellular vesicles
Feb 03, 2023
stRainy: assembly-based metagenomic strain phasing using long reads
Feb 03, 2023
CATE: A fast and scalable CUDA implementation to conduct highly parallelized evolutionary tests on large scale genomic data.
Feb 03, 2023
Self-supervised learning on millions of pre-mRNA sequences improves sequence-based RNA splicing prediction
Feb 03, 2023
Analysis of AlphaFold and molecular dynamics structure predictions of mutations in serpins
Feb 03, 2023
scDecouple: Decoupling cellular response and infection bias in scCRISPR-seq
Feb 03, 2023
A statistical approach to identify regulatory DNA variations
Feb 03, 2023
ViWrap: A modular pipeline to identify, bin, classify, and predict viral-host relationships for viruses from metagenomes
Feb 02, 2023
The omnitig framework can improve genome assembly contiguity in practice
Feb 02, 2023
A random forest model for predicting exosomal proteins using evolutionary information and motifs
Feb 02, 2023
When sex scarce: A rapid approach to sexing individuals by RAD-seq using a reference genome
Feb 02, 2023
midiaPASEF maximizes information content in data-independent acquisition proteomics
Feb 02, 2023
BIRDMAn: A Bayesian differential abundance framework that enables robust inference of host-microbe associations
Feb 02, 2023
When do longer reads matter? A benchmark of long read de novo assembly tools for eukaryotic genomes
Feb 02, 2023
Self-supervised learning for DNA sequences with circular dilated convolutional networks
Feb 01, 2023
Cell type matching across species using protein embeddings and transfer learning
Feb 01, 2023
Learning to Generate 5' UTR Sequences for Optimized Ribosome Load and Gene Expression
Feb 01, 2023
BZINB model-based pathway analysis and module identification facilitates integration of microbiome and metabolome data
Feb 01, 2023
Characterizing transcriptomic responses to sediment stress across location and morphology in reef-building corals
Feb 01, 2023
Uncovering the Consequences of Batch-Effect Associated Missing Values in Omics Data Analysis
Jan 31, 2023
Charge-State-Dependent Collision-Induced Dissociation Behaviors of RNA Oligonucleotides via High-Resolution Mass Spectrometry
Jan 31, 2023
Differentiable Partition Function Calculation for RNA
Jan 31, 2023
Study on the expression of RAD51 in non-small cell lung cancer based on bioinformatics
Jan 31, 2023
MHCnvex: Likelihood-based model for calling the copy number variations and loss of heterozygosity in MHC class I and II locus
Jan 31, 2023
Scalable neighbour search and alignment with uvaia
Jan 31, 2023
Quantitative Annotations of T-Cell Repertoire Specificity
Jan 31, 2023
Normative Modeling of Brain Morphometry Across the Lifespan using CentileBrain: Algorithm Benchmarking and Model Optimization
Jan 31, 2023
Single-cell multi-omic topic embedding reveals cell-type-specific and COVID-19 severity-related immune signatures
Jan 31, 2023
HLAProphet: Personalized allele-level quantification of the HLA proteins
Jan 31, 2023
On Pre-trained Language Models for Antibody
Jan 31, 2023
Optimizing the design of spatial genomic studies
Jan 31, 2023
Single-cell RNA sequencing reveals dysregulated fibroblast subclusters in prurigo nodularis
Jan 31, 2023
Data-driven optimization of biomarker panels in highly multiplexed imaging
Jan 31, 2023
Crafting negative training datasets for a high-performance classification of bacterial proteins secreted via non-classical pathways
Jan 31, 2023
Explainable prediction of catalysing enzymes from reactions using multilayer perceptrons
Jan 30, 2023
A dual diffusion model enables 3D binding bioactive molecule generation and lead optimization given target pockets
Jan 30, 2023
Decontamination of ambient and margin noise in droplet-based single cell protein expression data with DecontPro
Jan 30, 2023
PPAD: A deep learning architecture to predict progression of Alzheimer's disease
Jan 30, 2023
Performant web-based interactive visualization tool for spatially-resolved transcriptomics experiments
Jan 29, 2023
demuxmix: Demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models
Jan 29, 2023
Motifs in SARS-CoV-2 evolution
Jan 29, 2023
Co-evolution integrated deep learning framework for variants generation and fitness prediction
Jan 29, 2023
A quantitative approach to measure and predict microbiome response to antibiotics
Jan 28, 2023
Efficient image analysis for large-scale next generation histopathology using pAPRica
Jan 28, 2023
scGREAT: Graph-based regulatory element analysis tool for single-cell multi-omics data
Jan 28, 2023
HAT: de novo variant calling for highly accurate short-read and long-read sequencing data
Jan 28, 2023
DeepERA: deep learning enables comprehensive identification of drug-target interactions via embedding of heterogeneous data
Jan 28, 2023
Efficient estimation of breakpoints in piecewise-linear mixed-effects models for longitudinal ophthalmic studies
Jan 28, 2023
N-of-one differential gene expression without control samples using a deep generative model
Jan 28, 2023
Efficiently Quantifying DNA Methylation for Bulk- and Single-cell Bisulfite Data
Jan 27, 2023
The Hidradenitis Suppurativa 'Omics Database (HS-OmicsDB)
Jan 27, 2023
Multi-omics data integration approach identifies potential biomarkers for Prostate cancer
Jan 27, 2023
Protein Representation Learning via Knowledge Enhanced Primary Structure Modeling
Jan 27, 2023
L0 segmentation enables data-driven concise representations of diverse epigenomic data
Jan 27, 2023
Assessing the functional impact of protein binding site definition
Jan 27, 2023
Evaluating Retention Index Score Assumptions to Refine GC-MS Metabolite Identification
Jan 27, 2023
GRN-VAE: A Simplified and Stabilized SEM Model for Gene Regulatory Network Inference
Jan 27, 2023
The Ontology of Biological Attributes (OBA) - Computational Traits for the Life Sciences
Jan 27, 2023
Building a Pangenome Alignment Index via Recursive Prefix-Free Parsing
Jan 27, 2023
macrosyntR : Drawing automatically ordered Oxford Grids from standard genomic files in R
Jan 27, 2023
Adaptation of Graph Convolutional Neural Networks and Graph Layer-wise Relevance Propagation to the Spektral library with application to gene expression data of Colorectal Cancer patients
Jan 27, 2023
PortPred: exploiting deep learning embeddings of amino acid sequences for the identification of transporter proteins and their substrates
Jan 27, 2023
SeqPanther: Sequence manipulation and mutation statistics toolset
Jan 27, 2023
Species-aware DNA language modeling
Jan 27, 2023
decOM: Similarity-based microbial source tracking of ancient oral samples using k-mer-based methods
Jan 27, 2023
Cleavable crosslinkers redefined by novel MS3-trigger algorithm
Jan 26, 2023
SPEAR: a Sparse Supervised Bayesian Factor Model for Multi-omic Integration
Jan 26, 2023
Strain Tracking with Uncertainty Quantification
Jan 26, 2023
A deep learning approach for the discovery of tumor-targeting small organic ligands from DNA-Encoded Chemical Libraries
Jan 26, 2023
Adjustments to the reference dataset design improves cell type label transfer
Jan 26, 2023
Quantum mechanical electronic and geometric parameters for DNA k-mers as features for machine learning
Jan 26, 2023
An intrinsically interpretable neural network architecture for sequence to function learning
Jan 26, 2023
RAMEN identifies effective indicators for severe COVID and Long COVID patients
Jan 25, 2023
DISCO: A deep learning ensemble for uncertainty-aware segmentation of acoustic signals
Jan 25, 2023
The Multi-State Epigenetic Pacemaker enables the identification of combinations of factors that influence DNA methylation
Jan 25, 2023
A Comparison of Lossless Compression Methods in Microscopy Data Storage Applications
Jan 25, 2023
Investigating the Complexity of Gene Co-expression Estimation for Single-cell Data
Jan 25, 2023
Leveraging genomic redundancy to improve inference and alignment of orthologous proteins
Jan 25, 2023
The Impact of Multiple Sequence Alignment Error on Phylogenetic Estimation under Variable-Across-Phylogeny Substitution Models
Jan 25, 2023
The Impact of Species Tree Estimation Error on Cophylogenetic Reconstruction
Jan 25, 2023
Delineating genotypes and phenotypes of individual cells from long-read single cell transcriptomes
Jan 25, 2023
Cell Instance Segmentation via Multi-Scale Non-local Correlation
Jan 25, 2023
A new web resource to predict the impact of missense variants at protein interfaces using 3D structural data: Missense3D-PPI
Jan 25, 2023
Towards Analyzing the Reclassification Dynamics of ClinVar Variants
Jan 25, 2023
The Evolution of Local Energetic Frustration in Protein Families
Jan 25, 2023
E2EDA: Protein domain assembly based on end-to-end deep learning
Jan 25, 2023
Unlocking the Power of R: A High-Accuracy Method for Measuring DAB Staining on Immunohistochemical Slides
Jan 25, 2023
{Theta}-Net: Achieving Enhanced Phase-Modulated Optical Nanoscopy in silico through a computational 'string of beads' architecture
Jan 25, 2023
Impact of cross-ancestry genetic architecture on GWAS in admixed populations
Jan 24, 2023
Explain-seq: an end-to-end pipeline from training to interpretation of sequence-based deep learning models
Jan 24, 2023
Utility of long-read sequencing for All of Us
Jan 24, 2023
Delineation of complex gene expression patterns in single cell RNA-seq data with ICARUS v2.0
Jan 24, 2023
PolyAMiner-Bulk: A Machine Learning Based Bioinformatics Algorithm to Infer and Decode Alternative Polyadenylation Dynamics from bulk RNA-seq data
Jan 24, 2023
Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer PDXs
Jan 24, 2023
Accurate and fast graph-based pangenome annotation and clustering with ggCaller
Jan 24, 2023
NGS-enriched activated sludge modelling of an industrial wastewater treatment plant
Jan 24, 2023
Towards a reliable spatial analysis of missing features via spatially-regularized imputation
Jan 23, 2023
Assessing HLA imputation accuracy in a West African population
Jan 23, 2023
RawHash: Enabling Fast and Accurate Real-Time Analysis of Raw Nanopore Signals for Large Genomes
Jan 23, 2023
Accurate and interpretable gene expression imputation on scRNA-seq data using IGSimpute
Jan 23, 2023
Cont-ID:Detection of samples cross-contamination in viral metagenomic data
Jan 23, 2023
Novel Pipeline for Large-Scale Comparative Population Genetics
Jan 23, 2023
Minuteman - A versatile cloud computational platform for collaborative research
Jan 23, 2023
CompCorona: A Web Portal for Comparative Analysis of the Host Transcriptome of PBMC and Lung SARS-CoV-2, SARS-CoV, and MERS-CoV
Jan 23, 2023
In-silico Analysis of SARS-Cov2 Spike Proteins of Different Field Variants
Jan 23, 2023
Prediction of SARS-CoV-2 spike protein mutations using Sequence-to-Sequence and Transformer models
Jan 23, 2023
Pan-cancer Proteomics Analysis to Identify Tumor-Enriched and Highly Expressed Cell Surface Antigens as Potential Targets for Cancer Therapeutics
Jan 23, 2023
PC_sim: An integrated measure of protein sequence and structure similarity for improved alignments and evolutionary inference
Jan 22, 2023
Blind Assessment of Monomeric AlphaFold2 Protein Structure Models with Experimental NMR Data
Jan 22, 2023
Integrating disease genetics and drug bioassays to discover drug impacts on the human phenome
Jan 22, 2023
Gemini: Memory-efficient integration of hundreds of gene networks with high-order pooling
Jan 22, 2023
Accurate age prediction from blood using of small set of DNA methylation sites and a cohort-based machine learning algorithm
Jan 21, 2023
Prediction Analysis of Preterm Neonates Mortality using Machine Learning Algorithms via Python Programming
Jan 21, 2023
High tissue-specificity of lncRNAs maximises the prediction of tissue of origin of circulating DNA
Jan 21, 2023
TCGAnalyzeR: a web application for integrative visualization of molecular and clinical data of cancer patients for cohort discovery
Jan 21, 2023
VRPG: an interactive web viewer for reference pangenome graphs
Jan 21, 2023
Developing a robust technique for denoising and extracting speech and breath sounds in voice recordings from asthmatic patients
Jan 21, 2023
Structural Interaction Fingerprints and Machine Learning for predicting and explaining binding of small molecule ligands to RNA
Jan 15, 2023
Sensitive inference of alignment-safe intervalsfrom biodiverse protein sequence clusters usingEMERALD
Jan 15, 2023
Variational graph encoders: a surprisingly effective generalist algorithm for holistic computer-aided drug design
Jan 15, 2023
Cell segmentation for high-resolution spatial transcriptomics
Jan 15, 2023
Unveiling abundance-dependent metabolic phenotypes of microbial communities
Jan 15, 2023
Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation
Jan 15, 2023
Leveraging public transcriptome data with machine learning to infer pan-body age- and sex-specific molecular phenomena
Jan 15, 2023
GeneMark-ETP: Automatic Gene Finding in Eukaryotic Genomes in Consistence with Extrinsic Data
Jan 15, 2023
Deep-learning based bioactive peptides generation and screening against Xanthine oxidase
Jan 13, 2023
Mass spectrometry-based proteomics imputation using self supervised deep learning
Jan 13, 2023
Deep learning prediction boosts phosphoproteomics-based discoveries through improved phosphopeptide identification
Jan 12, 2023
nleval: A Python Toolkit for Generating Benchmarking Datasets for Machine Learning with Biological Networks
Jan 12, 2023
Identification of Cell-Type Specific Alternative Transcripts in the Multicellular Alga Volvox carteri
Jan 12, 2023
miRCurator: A rapid curation and analysis tool for plantmicroRNA studies
Jan 11, 2023
ODNA: Identification of Organellar DNA by Machine Learning
Jan 11, 2023
CellCharter: a scalable framework to chart and compare cell niches across multiple samples and spatial -omics technologies.
Jan 11, 2023
Benchmark and optimization of AlphaFold structures based virtual screening strategy
Jan 11, 2023
Origin Matters: Using a Local Reference Genome Improves Measures in Population Genomics
Jan 11, 2023
HOGVAX: Exploiting Peptide Overlaps to Maximize Population Coverage in Vaccine Design with Application to SARS-CoV-2
Jan 10, 2023
FastRecomb: Fast inference of genetic recombination rates in biobank scale data
Jan 10, 2023
BRDriver: Breast Cancer Driver Gene Predictor
Jan 10, 2023
CrossTx: Cross-cell line Transcriptomic Signature Predictions
Jan 10, 2023
Weakly-supervised temporal segmentation of cell-cycle stages with center-cell focus using Recurrent Neural Networks
Jan 09, 2023
Detection of circular RNAs and their potential as biomarkers predictive of drug response
Jan 09, 2023
Integration of chromatin accessibility and gene expression data with cisREAD reveals a switch from PU.1/SPIB-driven to AP-1-driven gene regulation during B cell activation
Jan 09, 2023
SemiBin2: self-supervised contrastive learning leads to better MAGs for short- and long-read sequencing
Jan 09, 2023
HQAlign: Aligning nanopore reads for SV detection using current-level modeling
Jan 09, 2023
Fluorescence Image Data with Sparse and Low-Rank Poisson Regression
Jan 08, 2023
Decoding CRISPR-Cas9 PAM recognition with UniDesign
Jan 08, 2023
Unsupervised Contrastive Peak Caller for ATAC-seq
Jan 08, 2023
Protein language model embedded geometric graphs power inter-protein contact prediction
Jan 08, 2023
Identification and Characterization of novel long non-coding RNAs in vascular smooth cells
Jan 08, 2023
DPHL v2: An updated and comprehensive DIA pan-human assay library for quantifying more than 14,000 proteins.
Jan 08, 2023
EnsDTI-kinase: Web-server for Predicting Kinase-Inhibitor Interactions with Ensemble Computational Methods and Its Applications
Jan 08, 2023
PASTE2: Partial Alignment of Multi-slice Spatially Resolved Transcriptomics Data
Jan 08, 2023
Epileptic seizure suppression: a computational approach for identification and control using real data
Jan 08, 2023
Conformational changes in the AdeB transmembrane efflux pump protein by amphiphilic peptide Mastoparan-B, down-regulates expression of the adeB Gene and restores antibiotics Susceptibility.
Jan 07, 2023
HiDDEN: A machine learning label refinement method for detection of disease-relevant populations in case-control single-cell transcriptomics
Jan 07, 2023
Hetnet connectivity search provides rapid insights into how two biomedical entities are related
Jan 07, 2023
Minimal Positional Substring Cover: A Haplotype Threading Alternative to Li & Stephens Model
Jan 06, 2023
Deep learning-driven fragment ion series classification enables highly precise and sensitive de novo peptide sequencing
Jan 06, 2023
Segmenting functional tissue units across human organs using community-driven development of generalizable machine learning algorithms
Jan 06, 2023
ChemGAPP; A Package for Chemical Genomics Analysis and Phenotypic Profiling.
Jan 06, 2023
CAT PETR: A Graphical User Interface for Differential Analysis of Phosphorylation Data
Jan 06, 2023
RabbitVar: ultra-fast and accurate somatic small-variant calling on multi-core architectures
Jan 06, 2023
ViralConsensus: A fast and memory-efficient tool for calling viral consensus genome sequences directly from read alignment data
Jan 06, 2023
Heterogeneous pseudobulk simulation enables realistic benchmarking of cell-type deconvolution methods
Jan 06, 2023
ConDoR: Tumor phylogeny inference with a copy-number constrained mutation loss model
Jan 06, 2023
The probability of edge existence due to node degree: a baseline for network-based predictions
Jan 06, 2023
When Geometric Deep Learning Meets Pretrained Protein Language Models
Jan 06, 2023
The Use of Class Imbalanced Learning Methods on ULSAM Data to Predict the Case-Control Status in Genome-Wide Association Studies
Jan 06, 2023
The metagenomic analysis of viral diversity in Colorado potato beetle public NGS data
Jan 05, 2023
CRISPR-Cas-Docker: Web-based in silico docking and machine learning-based classification of crRNAs with Cas proteins
Jan 05, 2023
Understanding and evaluating ambiguity in single-cell and single-nucleus RNA-sequencing
Jan 04, 2023
Unravelling cell type specific response to Parkinson's Disease at single cell resolution
Jan 04, 2023
Bioinformatics Approaches to Determine the Effect of SARS-CoV-2 Infection on Patients with Intrahepatic Cholangiocarcinoma
Jan 04, 2023
HPC-Atlas: Computationally Constructing A Comprehensive Atlas of Human Protein Complexes
Jan 04, 2023
ASTK: a software for comprehensive analysis of alternative splicing
Jan 04, 2023
Human embryonic tanycyte: heterogeneity and developmental trajectory
Jan 04, 2023
EpiMix: an integrative tool for epigenomic subtyping using DNA methylation
Jan 04, 2023
IsoAnalytics: A Single-cell Proteomics Web Server
Jan 04, 2023
Computational mutagenesis by using AUTO-MUTE 2.0 to examine X-ray crystallography structures for p53 and the impact of its resolution on predictions
Jan 04, 2023
Niche differential gene expression analysis in spatial transcriptomics data identifies context-dependent cell-cell interactions
Jan 04, 2023
PIsToN: Evaluating Protein Binding Interfaces with Transformer Networks
Jan 04, 2023
ElasticBLAST: Accelerating Sequence Search via Cloud Computing
Jan 04, 2023
Integrative proteogenomics using ProteomeGenerator2
Jan 04, 2023
Generalized tree structure to annotate untargeted metabolomics and stable isotope tracing data
Jan 04, 2023
MuLan-Methyl - Multiple Transformer-based Language Models for Accurate DNA Methylation Prediction
Jan 04, 2023
Reconstruction of 3-dimensional tissue organization at the single-cell resolution
Jan 04, 2023
How random is the review outcome? A systematic study of the impact of external factors on eLife peer review
Jan 04, 2023
AimSeg: a machine-learning-aided tool for axon, inner tongue and myelin segmentation
Jan 03, 2023
MASH Native: A Unified Solution for Native Top-Down Proteomics Data Processing
Jan 03, 2023
RNA-seq preprocessing and sample size considerations for gene network inference
Jan 03, 2023
DISCO+QR: Rooting Species Trees in the Presence of GDL and ILS
Jan 03, 2023
Scribe: next-generation library searching for DDA experiments
Jan 03, 2023
The Labbing Project: A database management application for neuroimaging research
Jan 03, 2023
Prediction of Polygenic Risk Score by Machine Learning and Deep Learning Methods in Genome-wide Association Studies
Jan 03, 2023
An RNA seq-based reference landscape of human normal and neoplastic brain
Jan 03, 2023
Sequence-to-sequence translation from mass spectra to peptides with a transformer model
Jan 03, 2023
In-silico monitoring of directed evolution convergence to unveil best performing variants with credibility score
Jan 03, 2023
Integrated Bioinformatics Analysis Reveals APEX1 as a Potential Biomarker for Septic Cardiomyopathy
Jan 03, 2023
On the correspondence between the transcriptomic response of a compound and its effects on its targets
Jan 02, 2023
RGT: a toolbox for the integrative analysis of high throughput regulatory genomics data
Jan 02, 2023
The Identification of Key Genes and Biological Pathways in Polycystic Ovary Syndrome and its Complications by Next Generation Squancing (NGS) and Bioinformatics Analysis
Jan 02, 2023
The new mega dataset combined with a deep neural network makes progress in predicting the impact of single mutations on protein stability
Jan 02, 2023
Development of digital Hi-C assay
Jan 02, 2023
Brain Electrical Bioactivity Informational Specifics in Relation to Behavioural and Cognitive Functions in Children with Learning Difficulties
Dec 31, 2022
Annotating metabolite mass spectra with domain-inspired chemical formula transformers
Dec 31, 2022
SAMBA: Structure-Learning of Aquaculture Microbiomes Using a Bayesian-Network Approach
Dec 31, 2022
Differential Roles of positive and negative supercoiling in compacting the E. coli genome
Dec 31, 2022
Prop3D: A flexible, Python-based platform for machine learning with protein structural properties and biophysical data
Dec 30, 2022
Closing the Bio-Silicon Loop for Cellular Neural Prosthesis using FPGA-based Iono-Neuromorphic Models
Dec 30, 2022
FunGeneTyper: An Expandable Deep Learning-based Framework for Ultra-accurate Classification and Discovery of Functional Protein-Coding Genes
Dec 30, 2022
Alternative Polyadenylation alters UBASH3B-ZNF652 competition to involve in Triple-Negative Breast Cancer
Dec 30, 2022
Latent representation of single-cell transcriptomes enables algebraic operations on cellular phenotypes
Dec 30, 2022
Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure prediction
Dec 30, 2022
A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence
Dec 30, 2022
Residue communities reveal evolutionary signatures of γδ T-Cell receptor
Dec 30, 2022
The Standard Genetic Code Lacks Redundancy for Amino Acid Codons
Dec 30, 2022
Optimized MNase-seq pipeline reveals a novel gene regulation via differential nucleosome stability
Dec 30, 2022
A probabilistic view of protein stability, conformational specificity, and design
Dec 30, 2022
A robust deep learning platform to predict CD8+ T-cell epitopes
Dec 29, 2022
Evaluation of the molecular diversity of Brazilian strains of the B.1.1 variant of SARS-CoV-2 used in vaccines
Dec 27, 2022
Epitopes- Based Vaccine Design Against Foot and Mouth Disease SAT2 Serotype from Sudanese Isolate by Using Immunoinformatic Approaches
Dec 27, 2022
Simultaneous visualization of cells and marker genes from scRNA-seq studies
Dec 27, 2022
CoBeL-RL: A neuroscience-oriented simulation framework for complex behavior and learning
Dec 27, 2022
Refinement of AlphaFold-Multimer structures with single sequence input
Dec 27, 2022
Enhanced antibody-antigen structure predictionfrom molecular docking using AlphaFold2
Dec 27, 2022
PROSTATA: Protein Stability Assessment using Transformers
Dec 26, 2022
betAS: intuitive analysis and visualisation of differential alternative splicing using beta distributions
Dec 26, 2022
FCGRT, a cancer-derived immunoglobulin G binding protein, mediates the malignant phenotype of glioma
Dec 26, 2022
Integrating spatial transcriptomics data across different conditions, technologies, and developmental stages
Dec 26, 2022
DeepRTAlign: toward accurate retention time alignment for large cohort mass spectrometry data analysis
Dec 25, 2022
Best: A Tool for Characterizing Sequencing Errors
Dec 23, 2022
HydRA: Deep-learning models for predicting RNA-binding capacity from protein interaction association context and protein sequence
Dec 23, 2022
Combination of Expert Guidelines-based and MachineLearning-based Approaches Leads to Superior Accuracy ofAutomated Prediction of Clinical Effect of Copy Number Variations
Dec 23, 2022
MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio High Fidelity reads
Dec 23, 2022
mapquik: Efficient low-divergence mapping of long reads in minimizer space
Dec 23, 2022
Guided-topic modelling of single-cell transcriptomes enables joint cell-type-specific and disease-subtype deconvolution of bulk transcriptomes with a focus on cancer studies
Dec 23, 2022
Inter-domain distance prediction based on deep learning for domain assembly
Dec 23, 2022
C-ToMExO: Learning Cancer Progression Dynamics from Clonal Composition of Tumors
Dec 23, 2022
plastiC: A pipeline for recovery and characterization of plastid genomes from metagenomic datasets
Dec 23, 2022
Neural Networks beyond explainability: Selective inference for sequence motifs
Dec 23, 2022
Uncovering context-specific genetic-regulation of gene expression from single-cell RNA-sequencing using latent-factor models
Dec 23, 2022
Detection of A-to-I microRNA editing with miRmedon reveals widespread co-editing of mature microRNA in the human brain
Dec 23, 2022
voyAGEr: free web interface for the analysis of age-related gene expression alterations in human tissues
Dec 23, 2022
LegNet: resetting the bar in deep learning for accurate prediction of promoter activity and variant effects from massive parallel reporter assays
Dec 23, 2022
16s rRNA gene sequence analysis of the microbial community on microplastic samples from the North Atlantic and Great Pacific Garbage Patches
Dec 22, 2022
Spatial transcriptomics deconvolution at single-cell resolution by Redeconve
Dec 22, 2022
Delineating mouse β-cell identity during lifetime and in diabetes with a single cell atlas
Dec 22, 2022
HAPNEST: efficient, large-scale generation and evaluation of synthetic datasets for genotypes and phenotypes
Dec 22, 2022
Enhanced Viral Metagenomics with Lazypipe 2
Dec 22, 2022
CRAM compression: practical across-technologies considerations for large-scale sequencing projects
Dec 22, 2022
TrAGEDy: Trajectory Alignment of Gene Expression Dynamics
Dec 22, 2022
FERMO: a Dashboard for Streamlined Rationalized Prioritization of Molecular Features from Mass Spectrometry Data
Dec 22, 2022
Detection of horizontal sequence transfer in microorganisms in the genomic era
Dec 22, 2022
MetaPredict: A machine learning-based tool for predicting metabolic modules in incomplete bacterial genomes
Dec 22, 2022
PeptideForest: Semisupervised machine learning integrating multiple search engines for peptide identification
Dec 22, 2022
Diagnosis with Confidence: Deep Learning for Reliable Classification of Squamous Lesions of the Upper Aerodigestive Tract
Dec 22, 2022
A method for differential expression analysis and pseudo- temporal locating and ordering of genes in single-cell transcriptomic data
Dec 22, 2022
Liam tackles complex multimodal single-cell data integration challenges
Dec 22, 2022
BioNumPy: Fast and easy analysis of biological data with Python
Dec 22, 2022
CIRCUST: a novel methodology for reconstruction of temporal order of molecular rhythms; validation and application towards a human circadian gene expression atlas
Dec 22, 2022
motifNet: Functional motif interactions discovered in mRNA sequences with implicit neural representation learning
Dec 21, 2022
Supervised discovery of interpretable gene programs from single-cell data
Dec 21, 2022
STrack: A tool to Simply Track bacterial cells in microscopy time-lapse images
Dec 21, 2022
End-to-end protein-ligand complex structure generation with diffusion-based generative models
Dec 21, 2022
LuxHMM: DNA methylation analysis with genome segmentation via Hidden Markov Model
Dec 21, 2022
Multimodal learning of noncoding variant effects using genome sequence and chromatin structure
Dec 21, 2022
Benchmarking single-cell hashtag oligo demultiplexing methods
Dec 21, 2022
Dissecting Complexity: The Hidden Impact of Application Parameters on Bioinformatics Research
Dec 21, 2022
AIRRSHIP: simulating human B cell receptor repertoire sequences
Dec 21, 2022
CAbiNet: Joint visualization of cells and genes based on a gene-cell graph
Dec 21, 2022
QRATER: a collaborative and centralized imaging quality control web-based application.
Dec 21, 2022
CircPrime: a web-based platform for design of specific circular RNA primers
Dec 20, 2022
Greengenes2 enables a shared data universe for microbiome studies
Dec 20, 2022
Genomic Distance-based Rapid Uncovering of Microbial Population Structures (GRUMPS): a reference free genomic data cleaning methodology
Dec 20, 2022
Universal chromatin state annotation of the mouse genome
Dec 20, 2022
HBM-CITEseq: a uniform CITE-seq processing pipeline for the HuBMAP Consortium
Dec 20, 2022
Mabs, a suite of tools for gene-informed genome assembly
Dec 20, 2022
BUSZ: Compressed BUS files
Dec 20, 2022
Robust clustering of transcriptomes through multiple testing
Dec 20, 2022
SGCI (Smartwatch Gait Coordination Index): New Measure for Human Gait Utilizing Smartwatch Sensor
Dec 20, 2022
Utilizing co-abundances of antimicrobial resistance genes to identify potential co-selection in the resistome
Dec 20, 2022
Diverse secondary metabolites are expressed in particle-associated and free-living microorganisms of the permanently anoxic Cariaco Basin
Dec 20, 2022
AFsample: Improving Multimer Prediction with AlphaFold using Aggressive Sampling
Dec 20, 2022
Leveraging a Billion-Edge Knowledge Graph for Drug Re-purposing and Target Prioritization using Genomically-Informed Subgraphs
Dec 20, 2022
EPEK: creation and analysis of an Ectopic Pregnancy Expression Knowledgebase
Dec 20, 2022
A refined pH-dependent coarse-grained model for peptide structure prediction in aqueous solution
Dec 20, 2022
Plant-PLMview: a database for identifying cis-regulatory sequences with preferential positions in gene-proximal regions of plants
Dec 20, 2022
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)
Dec 19, 2022
Codon language embeddings provide strong signals for protein engineering
Dec 19, 2022
Zero-shot reconstruction of mutant spatial transcriptomes
Dec 19, 2022
Handling ill-conditioned omics data with deep probabilistic models
Dec 19, 2022
novoRNABreak: local assembly for novel splice junction and fusion transcript detection from RNA-seq data
Dec 19, 2022
Varying molecular interactions explain crowder-dependent enzyme function of a viral protease
Dec 19, 2022
Structural characterizations of a unusual peptide CORO1C-47aa encoded by circRNA hsa-circ-0000437 associated with endometrial cancer
Dec 19, 2022
Finding the best cell lines across pan-cancer to use in pre-clinical research as a proxy for patient tumor samples considering immune cells, multi-omics, and cancer pathways
Dec 19, 2022
Filtering Methods for Asymmetric ODFs: Where and How Asymmetry Occurs in the White Matter
Dec 19, 2022
Hypergraphs and centrality measures identifying keyfeatures in gene expression data
Dec 19, 2022
Synthetic whole-slide image tile generation with gene expression profiles infused deep generative models
Dec 19, 2022
Tumor Segmentation using temporal Independent Component Analysis for DCE-MRI
Dec 19, 2022
MultiGML: Multimodal Graph Machine Learning for Prediction of Adverse Drug Events
Dec 19, 2022
De novo protein backbone generation based on diffusion with structured priors and adversarial training
Dec 19, 2022
Dashing Growth Curves - a web application for rapid and interactive analysis of microbial growth curves
Dec 19, 2022
Persistent spectral theory-guided protein engineering
Dec 19, 2022
SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data
Dec 19, 2022
Consistent typing of plasmids with the mge-cluster pipeline
Dec 19, 2022
Predicting transcription factor activity using prior biological information
Dec 19, 2022
DNA-protein quasi-mapping for rapid differential gene expression analysis in non-model organisms
Dec 19, 2022
The use of a graph database is a complementary approach to a classical similarity search for identifying commercially available fragment merges
Dec 19, 2022
Protein Language Model for Prediction of Subcellular Localization of Protein Sequences from Gram-negative bacteria (ProtLM.SCL)
Dec 19, 2022
Transformer-based tool recommendation system in Galaxy
Dec 19, 2022
Okapi-EM - a napari plugin for processing and analysing cryogenic serial FIB/SEM images
Dec 19, 2022
Accurate cell type deconvolution in spatial transcriptomics using a batch effect-free strategy
Dec 19, 2022
Assessing multiple evidence streams to decide on confidence for identification of post-translational modifications, within and across data sets
Dec 19, 2022
Estimating admixture pedigrees of recent hybrids without a contiguous reference genome
Dec 19, 2022
Detecting remote homolog using structure alignment algorithms and machine learning
Dec 19, 2022
Structure modeling and specificity of peptide-MHC class I interactions using geometric deep learning
Dec 19, 2022
Ot2Rec: A Semi-Automatic, Extensible, Multi-Software Tomographic Reconstruction Workflow
Dec 19, 2022
Startle: a star homoplasy approach for CRISPR-Cas9 lineage tracing
Dec 18, 2022
Evaluation of Mycobacterium Tuberculosis enrichment in metagenomic samples using ONT adaptive sequencing and amplicon sequencing for identification and variant calling
Dec 17, 2022
CAAStools, a toolbox to identify and test Convergent Amino Acid Substitutions.
Dec 16, 2022
Improving the prediction of white matter hyperintensities evolution in brain MRI of patients with small vessel disease using stroke lesions information
Dec 16, 2022
PyDESeq2: a python package for bulk RNA-seq differential expression analysis
Dec 16, 2022
Processing and evaluating the quality of genome-wide nascent transcription profiling libraries
Dec 16, 2022
BioASQ-QA: A manually curated corpus for Biomedical Question Answering
Dec 16, 2022
Unsupervized identification of prognostic copy-numberalterations using segmentation and lasso regularization
Dec 16, 2022
The necessity of considering enzymes as compartments in constraint-based genomescale metabolic models
Dec 16, 2022
Automated genome mining predicts combinatorial diversity and taxonomic distribution of peptide metallophore structures
Dec 16, 2022
Mirage2's high-quality spliced protein-to-genome mappings produce accurate multiple-sequence alignments of isoforms
Dec 16, 2022
E(3) equivariant graph neural networks for robust and accurate protein-protein interaction site prediction
Dec 16, 2022
Identifying indels from WGS short reads of haploid genomes distinguishes variant-calling algorithms
Dec 16, 2022
The impact of study design choices on significance and generalizability of canonical correlation analysis in neuroimaging studies
Dec 16, 2022
Integrating deep mutational scanning and low-throughput mutagenesis data to predict the impact of amino acid variants
Dec 16, 2022
Predicting the prevalence of complex genetic diseases from individual genotype profiles using capsule networks
Dec 15, 2022
First fully-automated AI/ML virtual screening cascade implemented at a drug discovery centre in Africa
Dec 15, 2022
NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis
Dec 15, 2022
MIDAS: a deep generative model for mosaic integration and knowledge transfer of single-cell multimodal data
Dec 15, 2022
Exact Probability Distribution for the ROC Area Under Curve
Dec 15, 2022
Alignment-based protein mutational landscape prediction: doing more with less
Dec 15, 2022
GeneSegNet: A deep learning framework for cell segmentation by integrating gene expression and imaging
Dec 15, 2022
Cell-type-specific co-expression inference from single cell RNA-sequencing data
Dec 15, 2022
Enhancer-driven gene regulatory networks inference from single-cell RNA-seq and ATAC-seq data
Dec 15, 2022
Single-nucleus co-expression networks of dopaminergic neurons support iron accumulation as a plausible explanation to their vulnerability in Parkinson's disease
Dec 15, 2022
A Versatile Deep Graph Contrastive Learning Framework for Single-cell Proteomics Embedding
Dec 15, 2022
Disentangling shared and group-specific variations in single-cell transcriptomics data with multiGroupVI
Dec 15, 2022
Merging short and stranded long reads improves transcript assembly
Dec 15, 2022
Enterotypes of the human gut mycobiome
Dec 15, 2022
De novo protein design by inversion of the AlphaFold structure prediction network
Dec 15, 2022
Crowdsourcing Temporal Transcriptomic Coronavirus Host Infection Data: resources, guide, and novel insights.
Dec 15, 2022
Embedding-based alignment: combining protein language models and alignment approaches to detect structural similarities in the twilight-zone
Dec 15, 2022
Mean Dimension of Generative Models for Protein Sequences
Dec 14, 2022
Proteome-wide structure-based accessibility analysis of ligandable and detectable cysteines in chemoproteomic datasets
Dec 14, 2022
COVID-19db linkage maps of cell surface proteins and transcription factors in immune cells
Dec 14, 2022
Genome-wide analysis of dry (Tamar) Date palm fruit color
Dec 14, 2022
Pan-cancer transcriptomic analysis reveals a tissue-specific loss of identity
Dec 14, 2022
FrustraPocket: A protein-ligand binding site predictor using energetic local frustration
Dec 14, 2022
Evaluation of a scalable approach to generate cell-type specific transcriptomic profiles of mesenchymal lineage cells
Dec 14, 2022
The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy
Dec 14, 2022
Joint inference of transcription factor activity and context-specific regulatory networks
Dec 14, 2022
Application of Aligned-UMAP to longitudinal biomedical studies
Dec 14, 2022
Generalizing the isothermal efficiency by using Gaussian distributions
Dec 14, 2022
Mass Dynamics 2.0: An improved modular web-based platform for accelerated proteomics insight generation and decision making
Dec 14, 2022
Quantifying B-cell Clonal Diversity In Repertoire Data
Dec 14, 2022
PaleoProPhyler: a reproducible pipeline for phylogenetic inference using ancient proteins
Dec 13, 2022
PYPE: A Python pipeline for phenome-wide association (PheWAS) and mendelian randomization in investigator-driven phenotypes and genotypes of biobank data
Dec 13, 2022
Long COVID: G Protein-Coupled Receptors (GPCRs) responsible for persistent post-COVID symptoms
Dec 13, 2022
SpaGFT is a graph Fourier transform for tissue module identification from spatially resolved transcriptomics
Dec 13, 2022
Fibroblast Growth Factor 5 (FGF5) and Its Missense Mutant FGF5-Y174H Underlying Trichomegaly: A Molecular Dynamics Simulation Investigation
Dec 13, 2022
SWAMPy: Simulating SARS-CoV-2 Wastewater Amplicon Metagenomes with Python
Dec 12, 2022
Exploring B and T-cell epitopes for constructing a Novel Multiepitope vaccine to combat emerging Monkeypox infection: A Reverse Vaccinology approach
Dec 12, 2022
Structural Insights into Pink-eyed Dilution Protein (Oca2)
Dec 12, 2022
Origin, evolution and diversification of plant mechanosensitive channel of small conductance-like (MSL) proteins
Dec 12, 2022
Biological Cartography: Building and Benchmarking Representations of Life
Dec 12, 2022
Web-based Tool Validation for Antimicrobial Resistance Prediction: An Empirical Comparative Analysis
Dec 12, 2022
Identifying key residues in intrinsically disordered regions of proteins using machine learning
Dec 12, 2022
TargetCall: Eliminating the Wasted Computation in Basecalling via Pre-Basecalling Filtering
Dec 12, 2022
Identification of a covert evolutionary pathway between two protein folds
Dec 12, 2022
3D multiplexed tissue imaging reconstruction and optimized region-of-interest (ROI) selection through deep learning model of channels embedding
Dec 12, 2022
Phantasus: web-application for visual and interactive gene expression analysis
Dec 12, 2022
Snakeobjects: an object-oriented workflow management system
Dec 12, 2022
Foldcomp: a library and format for compressing and indexing large protein structure sets
Dec 12, 2022
SpLitteR: Diploid genome assembly using linked TELL-Seq reads and assembly graphs
Dec 12, 2022
md_harmonize: a Python package for atom-level harmonization of public metabolic data-bases
Dec 12, 2022
Cell shape characterization, alignment and comparison using FlowShape
Dec 12, 2022
Towards a Clinically-based Common Coordinate Framework for the Human Gut Cell Atlas - The Gut Models
Dec 12, 2022
RNA-Chrom: a manually-curated analytical database of RNA-chromatin interactome
Dec 12, 2022
Learning orientation-invariant representations enables accurate and robust morphologic profiling of cells and organelles
Dec 12, 2022
Correction of transposase sequence bias in ATAC-seq data with rule ensemble modeling
Dec 12, 2022
Creating an Ignorance-Base: Exploring Known Unknowns in the Scientific Literature
Dec 12, 2022
SAINT-Angle: self-attention augmented inception-inside-inception network and transfer learning improve protein backbone torsion angle prediction
Dec 12, 2022
dgram2dmap: Extraction, visualisation and formatting of distance constraints from AlphaFold distograms
Dec 12, 2022
scTensor detects many-to-many cell-cell interactions from single cell RNA-sequencing data
Dec 12, 2022
Evaluation of AlphaFold-Multimer prediction on multi-chain protein complexes
Dec 12, 2022
MAD HATTER correctly annotates 98% of small molecule tandem mass spectra searching in PubChem
Dec 12, 2022
IIIandMe: An Algorithm for Chromosome-scale Haplotype Determination Using Genome-wide Variants of Three Haploid Reproductive Cells
Dec 12, 2022
Cryo-EM map anisotropy can be attenuated by map post-processing and a new method for its estimation
Dec 12, 2022
Graph neural networks learn emergent tissue properties from spatial molecular profiles
Dec 11, 2022
Improving prediction of drug-target interactions based on fusing multiple features with data balancing and feature selection techniques
Dec 10, 2022
scEvoNet: a gradient boosting-based method for prediction of cell state evolution
Dec 10, 2022
Bayesian clustering with uncertain data
Dec 10, 2022
Integrated Single-Dose Kinome Profiling Data is Predictive of Cancer Cell Line Sensitivity to Kinase Inhibitors
Dec 10, 2022
AutoGater: A Weakly Supervised Neural Network Model to Gate Cells in Flow Cytometric Analyses
Dec 10, 2022
Points2regions: Fast Interactive Clustering Of In Situ Transcriptomics Data
Dec 10, 2022
Whole slide image representation in bone marrow cytology
Dec 10, 2022
Baseline Acute Myeloid Leukemia Prognosis Models using Transcriptomic and Clinical Profiles by Studying the Impacts of Dimensionality Reductions and Gene Signatures on Cox-Proportional Hazard
Dec 10, 2022
General stain deconvolution of histopathology images with physics-guided deep learning
Dec 10, 2022
Learning the Drug-Target Interaction Lexicon
Dec 10, 2022
metaDMG - A Fast and Accurate Ancient DNA Damage Toolkit for Metagenomic Data
Dec 09, 2022
ModelCIF: An extension of PDBx/mmCIF data representation for computed structure models
Dec 09, 2022
Improvement of protein tertiary and quaternary structure predictions using the ReFOLD4 refinement method and the AlphaFold2 recycling process
Dec 09, 2022
Structural pre-training improves physical accuracy of antibody structure prediction using deep learning.
Dec 09, 2022
Identifying B-cell epitopes using AlphaFold2 predicted structures and pretrained language model
Dec 09, 2022
Discovering Haematoma-Stimulated Circuits for Secondary Brain Injury after Intraventricular Haemorrhage by Spatial Transcriptome Analysis
Dec 09, 2022
Learning the differences: a transfer-learning approach to predict antigen immunogenicity and T-cell receptor specificity
Dec 09, 2022
wastewaterSPAdes: SARS-CoV-2 strain deconvolution using SPAdes toolkit
Dec 09, 2022
From Multi-Allele Fish to Non-Standard Environments, How ZFIN Assigns Phenotypes, Human Disease Models, and Gene Expression Annotations to Genes
Dec 08, 2022
Dysfunctional analysis of the pre-training model on nucleotide sequences and the evaluation of different k-mer embeddings
Dec 08, 2022
NetGO 3.0: Protein Language Model Improves Large-scale Functional Annotations
Dec 08, 2022
Optimising a coordinate ascent algorithm for the meta-analysis of test accuracy studies
Dec 08, 2022
Fast and accurate protein function prediction from sequence through pretrained language model and homology-based label diffusion
Dec 08, 2022
Megan Server: facilitating interactive access to metagenomic data on a server
Dec 08, 2022
M-Band Wavelet-Based Imputation of scRNA-seq Matrix and Multi-view Clustering of Cell
Dec 08, 2022
A Meta-analysis of 2D vs. 3D Ovarian Cancer Cellular Models
Dec 08, 2022
Atlas-scale single-cell multi-sample multi-condition data integration using scMerge2
Dec 08, 2022
Exploring the intricacies and pitfalls of the ATN framework: An assessment across cohorts and thresholding methodologies
Dec 08, 2022
BCLncRDB: A comprehensive database of LncRNAs associated with breast cancer
Dec 08, 2022
MembraneFold: Visualising transmembrane protein structure and topology
Dec 08, 2022
Discordant results among MHC binding affinity prediction tools
Dec 07, 2022
Deep Local Analysis deconstructs protein-protein interfaces and accurately estimates binding affinity changes upon mutation
Dec 07, 2022
Anti-correlated Feature Selection Prevents False Discovery of Subpopulations in scRNAseq
Dec 07, 2022
Monopogen: single nucleotide variant calling from single cell sequencing
Dec 07, 2022
Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells
Dec 07, 2022
The Inherited Rate Matrix algorithm for phylogenetic model selection for non-stationary Markov processes
Dec 07, 2022
rcCAE: a convolutional autoencoder based method for detecting tumor clones and copy number alterations from single-cell DNA sequencing data
Dec 07, 2022
Genome charaterization based on the Spike-614 and NS8-84 loci of SARS-CoV-2 reveals two major onsets of the COVID-19 pandemic
Dec 06, 2022
Sharing Massive Biomedical Data at Magnitudes Lower Bandwidth Using Implicit Neural Function
Dec 05, 2022
The PRALINE database: Protein and Rna humAn singLe nucleotIde variaNts in condEnsates
Dec 05, 2022
GDockScore: a graph-based protein-protein dockingscoring function
Dec 05, 2022
A knowledge-based system for personalised lifestyle recommendations: Design and simulation of potential effectiveness on the UK Biobank data
Dec 05, 2022
Covidscope: An atlas-scale COVID-19 resource for single-cell meta analysis at sample and cell levels
Dec 05, 2022
DiffDomain enables identification of structurally reorganized topologically associating domains
Dec 05, 2022
Performance of computational algorithms to deconvolve heterogeneous bulk tumor tissue depends on experimental factors
Dec 05, 2022
cazy_webscraper: local compilation and interrogation of comprehensive CAZyme datasets
Dec 03, 2022
Investigating graph neural network for RNA structural embedding
Dec 03, 2022
Evolutionary shortcuts via multi-nucleotide substitutions and their impact on natural selection analyses.
Dec 03, 2022
Finemap-MiXeR: A variational Bayesian approach for genetic finemapping
Dec 02, 2022
Statistical tests to detect differences between codon-specific Ramachandran plots
Dec 02, 2022
HTRX: an R package for learning non-contiguous haplotypes associated with a phenotype
Dec 02, 2022
Does Inter-Protein Contact Prediction Benefit from Multi-Modal Data and Auxiliary Tasks?
Dec 02, 2022
Improving Protein Subcellular Localization Prediction with Structural Prediction & Graph Neural Networks
Dec 02, 2022
Gene Set Scoring on the Nearest Neighbor Graph (gssnng) for Single Cell RNA-seq (scRNA-seq)
Dec 02, 2022
Contrastive learning of protein representations with graph neural networks for structural and functional annotations
Dec 02, 2022
TissUUmaps 3 Tools for Visualization & Quality Control in Large-scale Multiplex Tissue Analysis
Dec 02, 2022
Genetic fine-mapping from summary data using a non-local prior improves detection of multiple causal variants
Dec 02, 2022
CRMnet: a deep learning model for predicting gene expression from large regulatory sequence datasets
Dec 02, 2022
GOThresher: a program to remove annotation biases from protein function annotation datasets
Dec 02, 2022
Accurate quantification of single-nucleus and single-cell RNA-seq transcripts
Dec 02, 2022
Illuminating protein space with a programmable generative model
Dec 02, 2022
Annotation-agnostic discovery of associations between novel gene isoforms and phenotypes
Dec 02, 2022
MLcps: Machine Learning Cumulative Performance Score for classification problems
Dec 02, 2022
Secure and Federated Genome-Wide Association Studies for Biobank-Scale Datasets
Dec 02, 2022
Prediction and Curation of Missing Biomedical Identifier Mappings with Biomappings
Dec 02, 2022
WASCO: A Wasserstein-based statistical tool to compare conformational ensembles of intrinsically disordered proteins
Dec 02, 2022
Assessing the Nucleotide-Level Impact of Spaceflight Stress using RNA-Sequencing Data
Dec 02, 2022
PfaSTer: A ML-powered serotype caller for Streptococcus pneumoniae genomes
Dec 02, 2022
Chimeric U-Net - Modifying the standard U-Net towards Explainability
Dec 02, 2022
YOUNG PLASMA REJUVENATES BLOOD DNA METHYLATION PROFILE, PROLONGS MEAN LIFESPAN AND IMPROVES HEALTH IN OLD RATS
Dec 02, 2022
Predicting Drug Repurposing Candidates and Their Mechanisms from A Biomedical Knowledge Graph
Dec 02, 2022
Metacell projection for interpretable and quantitative use of transcriptional atlases
Dec 02, 2022
Effect of D128N mutation on OsSERK2 in Xa21 mediated immune complex: an in-silico study
Dec 02, 2022
Variational inference accelerates accurate DNA mixture deconvolution
Dec 02, 2022
Dynamic Data Independent Acquisition Mass Spectrometry with Real-Time Retrospective Alignment
Dec 02, 2022
TMvisDB: resource for transmembrane protein annotation and 3D visualization
Dec 02, 2022
Predicting Immune Escape with Pretrained Protein Language Model Embeddings
Dec 02, 2022
Proteomic profiling identifies biomarkers of COVID-19 severity
Nov 30, 2022
DAPTEV: Deep aptamer evolutionary modelling for COVID-19 drug design
Nov 30, 2022
Common gene signature model discovery and systematic validation for TB prognosis and response to treatment
Nov 30, 2022
predatoR: an R package for network-based mutation impact prediction
Nov 30, 2022
Methylmap: visualization of modified nucleotides for large cohort sizes
Nov 30, 2022
T-cell receptor specific protein language model for prediction and interpretation of epitope binding (ProtLM.TCR)
Nov 29, 2022
ARCHE: A HIERARCHICAL, EASY TO DOWNLOAD, FUNCTIONAL-OPTIMIZED ANNOTATOR FOR MICROBIAL META(GENOMES)
Nov 29, 2022
Rethinking bacterial relationships in light of their molecular abilities
Nov 29, 2022
Imputation of low-coverage sequencing data from 150,119 UK Biobank genomes
Nov 29, 2022
Computational deconvolution of fifteen leukocyte subtypes from DNA methylation microarrays trained on flow cytometry data in the Health and Retirement Study
Nov 29, 2022
Brewpitopes: a pipeline to refine B-cell epitope predictions during public health emergencies
Nov 29, 2022
NanoPack2: Population scale evaluation of long-read sequencing data
Nov 29, 2022
NanoTrans: an integrated computational framework for comprehensive transcriptome analyses with Nanopore direct-RNA sequencing
Nov 29, 2022
Real-time biochemical-free targeted sequencing of RNA species with RISER
Nov 29, 2022
Exploring Xylella fastidiosa's metabolic traits using a GSM model of the phytopathogenic bacterium
Nov 29, 2022
Multifaceted quality assessment of gene repertoire annotation with OMArk
Nov 28, 2022
CommonNNClustering--A Python package for generic common-nearest-neighbour clustering
Nov 28, 2022
PhosphoLingo: protein language models for phosphorylation site prediction
Nov 28, 2022
ViCloD, an interactive web tool for visualizing B cell repertoires and analyzing intra-clonal diversities: application to human B-cell tumors
Nov 28, 2022
CiliaMiner: an integrated database for Ciliopathy Genes and Ciliopathies
Nov 28, 2022
Fast protein structure searching using structure graph embeddings
Nov 28, 2022
SlideCNA: Spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data
Nov 27, 2022
Deep Learning for Predicting 16S rRNA Copy Number
Nov 27, 2022
Identification of novel natural product inhibitors of BRD4 using high throughput virtual screening and MD simulation
Nov 27, 2022
A 3D genome atlas of genetic variants and their pathological effects
Nov 27, 2022
Inferring delays in partially observed gene regulatory networks
Nov 27, 2022
Deep Domain Adversarial Neural Network for the Deconvolution of Cell Type Mixtures in Tissue Proteome Profiling
Nov 25, 2022
scCDC: a computational method for gene-specific contamination detection and correction in single-cell and single-nucleus RNA-seq data
Nov 25, 2022
Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell ageing
Nov 25, 2022
Visualization of Incrementally Learned Projection Trajectories for Longitudinal Data
Nov 25, 2022
RNAlysis: analyze your RNA sequencing data without writing a single line of code
Nov 25, 2022
PRESGENE: A web server for PRediction of ESsential GENE using integrative machine learning strategies
Nov 25, 2022
Predicting and Interpreting Protein Developability via Transfer of Convolutional Sequence Representation
Nov 25, 2022
Developing best practices for genotyping-by-sequencing analysis using linkage maps as benchmarks
Nov 25, 2022
pLM-BLAST - distant homology detection based on direct comparison of sequence representations from protein language models
Nov 25, 2022
ADeS: a deep learning based Apoptosis Detection System for live cell imaging.
Nov 25, 2022
MAGE: Strain Level Profiling of MetagenomeSamples
Nov 25, 2022
Predicting Lung Cancer in Korean Never-Smokers with Polygenic Risk Scores
Nov 25, 2022
Dynamic Interaction Learning and MultimodalRepresentation for Drug Response Prediction
Nov 25, 2022
SCALA: A web application for multimodal analysis of single cell next generation sequencing data
Nov 25, 2022
Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands
Nov 25, 2022
Consensus Label Propagation with Graph Convolutional Networks for Single-Cell RNA Sequencing Cell Type Annotation
Nov 25, 2022
Re-implementation of an algorithm to integrate transcriptome and ChIP-seq data
Nov 25, 2022
Accurate microRNA annotation of animal genomes using trained covariance models of curated microRNA complements in MirMachine
Nov 25, 2022
Evaluating spatially variable gene detection methods for spatial transcriptomics data
Nov 25, 2022
Matrix prior for data transfer between single cell data types in latent Dirichlet allocation
Nov 25, 2022
MSdb: an integrated expression atlas of human musculoskeletal system
Nov 25, 2022
BLEND: A Fast, Memory-Efficient, and Accurate Mechanism to Find Fuzzy Seed Matches in Genome Analysis
Nov 25, 2022
ExposomeX: Integrative Exposomic Platform Expediates Discovery of "Exposure-Biology-Disease" Nexus
Nov 25, 2022
CRISPRi-FGP: web-based genome-scale CRISPRi sgRNA design and validation tool in prokaryotes
Nov 25, 2022
Improving protein secondary structure prediction by deep language models and transformer networks
Nov 24, 2022
Interactive explainable AI platform for graph neural networks
Nov 24, 2022
Expression profiles of hypoxia-related genes of cancers originating from anatomically similar locations using TCGA database analysis
Nov 24, 2022
Optimization-Based Decoding of Imaging Spatial Transcriptomics Data
Nov 24, 2022
Peptide-MHC Structure Prediction With Mixed Residue and Atom Graph Neural Network
Nov 24, 2022
Terraces in Species Tree Inference from Gene Trees
Nov 24, 2022
A Novel Approach to Topological Network Analysis for the Identification of Metrics and Signatures in Non-Small Cell Lung Cancer
Nov 24, 2022
Node-degree aware edge sampling mitigates inflated classification performance in biomedical graph representation learning
Nov 24, 2022
Region- and variance-based DNA methylation analyses reveal novel disease genes and pathways for systemic lupus erythematosus
Nov 24, 2022
MerCat2: a versatile k-mer counter and diversity estimator for database-independent property analysis obtained from omics data
Nov 24, 2022
k2v: A Containerized Workflow for Creating VCF Files from Kintelligence Targeted Sequencing Data
Nov 24, 2022
Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency
Nov 24, 2022
CASBERT: BERT-Based Retrieval for Compositely Annotated Biosimulation Model Entities
Nov 24, 2022
Multi-layer guilt-by-association-based drug repurposing by integrating clinical knowledge on biological heterogeneous networks
Nov 24, 2022
Rapid Real-time Squiggle Classification for Read Until Using RawMap
Nov 24, 2022
Evolution of drug resistance drives progressive destabilizations in functionally conserved molecular dynamics of the flap region of the HIV-1 protease
Nov 24, 2022
gtexture: Haralick texture analysis for graphs and its application to biological networks
Nov 24, 2022
excluderanges: exclusion sets for T2T-CHM13, GRCm39, and other genome assemblies
Nov 24, 2022
Fragment-Based Hit Discovery via Unsupervised Learning of Fragment-Protein Complexes
Nov 24, 2022
HAPPY: A deep learning pipeline for mapping cell-to-tissue graphs across placenta histology whole slide images
Nov 24, 2022
Starfysh reveals heterogeneous spatial dynamics in the breast tumor microenvironment
Nov 24, 2022
RE2DC: a robust and efficient 2D classifier with visualization for processing massive and heterogeneous cryo-EM data
Nov 24, 2022
Identifying Protein Haplotypes by Mass Spectrometry
Nov 24, 2022
Database of recurrent mutations (DORM), a web tool to browse recurrent mutations in cancers
Nov 24, 2022
Quantitative assessment of association between noncoding variants and transcription factor binding
Nov 23, 2022
Accuracy and completeness of long read metagenomic assemblies
Nov 23, 2022
Computational investigations in inhibition of alcohol/aldehyde dehydrogenase in lignocellulosic hydrolysates
Nov 22, 2022
SUMO - In Silico Sequence Assessment Using Multiple Optimization Parameters
Nov 22, 2022
Plastid Genome Assembly Using Long-read Data (ptGAUL)
Nov 22, 2022
Does AlphaFold predict the spatial structure of a protein from physics or recognize it (its main parts and their association) using databases?
Nov 22, 2022
Computational Pipeline to Identify Gene signatures that Define Cancer Subtypes
Nov 22, 2022
OpenFold: Retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization
Nov 22, 2022
Identification of Key Genes and Underlying Mechanisms in Cystic fibrosis and its Associated Complications Based on Bioinformatics Analysis of Next Generation Sequencing Data Analysis
Nov 22, 2022
Predicting lifespan-extending chemical compounds with machine learning and biologically interpretable features
Nov 22, 2022
scFormer: A Universal Representation Learning Approach for Single-Cell Data Using Transformers
Nov 22, 2022
Updated benchmarking of variant effect predictors using deep mutational scanning
Nov 22, 2022
Single-Cell ATAC-seq analysis via Network Refinement with peaks location information
Nov 22, 2022
Polymorphic regions in BA.2.12.1, BA.4 and BA.5 likely implicated in immunological evasion of Omicron subvariant BQ.1.1
Nov 21, 2022
SARS-CoV-2 variant transition dynamics are associated with vaccination rates, number of co-circulating variants, and natural immunity
Nov 21, 2022
Decoding protein binding landscape on circular RNAs with base-resolution Transformer models
Nov 20, 2022
HoCoRT: Host contamination removal tool
Nov 20, 2022
Network Based Identification of Holistic Drug Target for Parkinson Disease and Deep Learning assisted Drug Repurposing.
Nov 20, 2022
SurvBoard: Standardised Benchmarking for Multi-omics Cancer Survival Models
Nov 20, 2022
CAGEE: computational analysis of gene expression evolution
Nov 20, 2022
An Automatized Workflow to Study Mechanistic Indicators for Driver Gene Prediction with Moonlight
Nov 20, 2022
Running ahead of evolution - AI based simulation for predicting future high-risk SARS-CoV-2 variants
Nov 19, 2022
Structural, functional and evolutionary analysis of wheat WRKY45 protein: A combined bioinformatics and MD simulation approach
Nov 19, 2022
A comparative study of neuroendocrine heterogeneity in SCLC and NBL
Nov 18, 2022
Cell-type annotation with accurate unseen cell-type identification using multiple references
Nov 18, 2022
Evaluating the analytical validity of mutation calling pipeline for tumor whole exome sequencing
Nov 18, 2022
Integrated single cell analysis reveals co-evolution of malignant B cells and the tumor microenvironment in transformed follicular lymphoma
Nov 18, 2022
TimiGP: inferring inter-cell functional interactions and clinical values in the tumor immune microenvironment through gene pairs
Nov 18, 2022
PlantTribes2: tools for comparative gene family analysis in plant genomics
Nov 18, 2022
Inferring ligand-receptor cellular networks from bulk and spatial transcriptomic datasets with BulkSignalR
Nov 18, 2022
CLOOME: a new search engine unlocks bioimaging databases for queries with chemical structures
Nov 18, 2022
Bioinformatic methods for stratification of obese patients and identification of cancer susceptibility biomarkers based on the analysis of the gut microbiome
Nov 18, 2022
Finding Consensus miRNAs Silencing KLF1 Expression as A Promising Therapeutic Option of Sickle Cell Anemia
Nov 18, 2022
Reference genome sequences of Mythimna separata (Lepidoptera: Noctuidae)
Nov 18, 2022
Analysis of spatial transcriptomics at varying resolution levels using the unified framework of SpaSEG
Nov 17, 2022
Inferring the distributions of fitness effects and proportions of strongly deleterious mutations
Nov 17, 2022
Purging genomes of contamination eliminates systematic bias from evolutionary analyses of ancestral genomes
Nov 17, 2022
Explainable Deep Generative Models, Ancestral Fragments, and Murky Regions of the Protein Structure Universe
Nov 17, 2022
Quality control for the target decoy approach for peptide identification
Nov 17, 2022
ECOLE: Learning to call copy number variants on whole exome sequencing data
Nov 17, 2022
Snapper: a high-sensitive algorithm to detect methylation motifs based on Oxford Nanopore reads
Nov 17, 2022
The effect of background noise and its removal on the analysis of single-cell expression data
Nov 17, 2022
MatchCLOT: Single-Cell Modality Matching with Contrastive Learning and Optimal Transport
Nov 17, 2022
KBPRNA: A novel method integrating bulk RNA-seq data and LINCS-L1000 gene signatures to predict kinase activity based on machine learning
Nov 17, 2022
gGN: learning to represent graph nodes as low-rank Gaussian distributions
Nov 17, 2022
Versatile detection of diverse selective sweeps with Flex-sweep
Nov 17, 2022
Conformational epistasis impairs AlphaFold structural predictions
Nov 17, 2022
ChromFormer: A transformer-based model for 3Dgenome structure prediction
Nov 17, 2022
Deep Representation Learning Determines Drug Mechanism of Action from Cell Painting Images
Nov 17, 2022
PSMC2 and CXCL8-Modulated Four Critical Gene Biomarkers and Druggable and Vaccinable Targets for Colorectal Cancer
Nov 17, 2022
DeepBryo: a web app for AI-assisted morphometric characterization of cheilostome bryozoans
Nov 17, 2022
Inferring a cell's capabilities from omics data with ImmCellFie
Nov 17, 2022
Genome-wide single-molecule analysis of long-read DNA methylation reveals heterogeneous patterns at heterochromatin
Nov 16, 2022
Revisiting pangenome openness with k-mers
Nov 16, 2022
A pan-cancer interrogation of intronic polyadenylation and its association with cancer characteristics
Nov 16, 2022
The repertoire of copy number alteration signatures in human cancer
Nov 16, 2022
Ultra-fast protein structure prediction to capture effects of sequence variation in mutation movies
Nov 16, 2022
CRitical Assessment of genomic COntamination detection at several Taxonomic ranks (CRACOT)
Nov 16, 2022
Application of a Latent Trait Modeling Method for Missing Data Across Datasets: Guidance on Appropriate Factor Structure
Nov 16, 2022
MOT: a Multi-Omics Transformer for multiclass classification tumour types predictions
Nov 16, 2022
Context-Aware Transcript Quantification from Long Read RNA-Seq data with Bambu
Nov 16, 2022
CREPE: A Shiny App for Transcription Factor Cataloguing
Nov 16, 2022
Deep-learning based bioactive therapeutic peptides generation and screening
Nov 16, 2022
Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma
Nov 15, 2022
A Microfluidic Device to Simulate the Impact of Gut Microbiome in Cancer
Nov 15, 2022
Computational Design of a New Aflatoxin B1 Aptamer in lieu of SELEX Technique
Nov 15, 2022
A universal differential expression prediction tool for single-cell and spatial genomics data
Nov 15, 2022
AGouTI - flexible Annotation of Genomic and Transcriptomic Intervals
Nov 15, 2022
Using conditional Generative Adversarial Networks (GAN) to generate de novo synthetic cell nuclei for training machine learning-based image segmentation
Nov 15, 2022
FASSO: An AlphaFold based method to assign functional annotations by combining sequence and structure orthology
Nov 15, 2022
ACNN-6mA: Prediction of N6-Methyladenine Loci in Multiple Species Based on Rice Dataset Pre-training Model
Nov 15, 2022
A consensus score to combine inferences from multiple centres
Nov 14, 2022
VarSCAT: A computational tool for sequence context annotations of genomic variants
Nov 14, 2022
A Bioinformatic Study of the Distribution of Mn Oxidation Proteins in Sequenced Bacterial Genomes
Nov 14, 2022
Effect of Human microRNA on Dengue Virus Genome: a cross-specie approach
Nov 14, 2022
BeEM: fast and faithful conversion of mmCIF format structure files to PDB format
Nov 14, 2022
Rockfish: A Transformer-based Model for Accurate 5-Methylcytosine Prediction from Nanopore Sequencing
Nov 14, 2022
Turnover number predictions for kinetically uncharacterized enzymes using machine and deep learning
Nov 14, 2022
Generative modeling of short, disordered proteins with homogeneous sequence composition
Nov 14, 2022
Customized genomes for human and mouse ribosomal DNA mapping
Nov 14, 2022
Highly Realistic Whole Transcriptome Synthesis through Generative Adversarial Networks
Nov 14, 2022
Reconciliation and Evolution of Penicillium rubens Genome-Scale Metabolic Networks - What about Specialised Metabolism?
Nov 14, 2022
The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling
Nov 13, 2022
STREAK: A Supervised Cell Surface Receptor Abundance Estimation Strategy for Single Cell RNA-Sequencing Data using Feature Selection and Thresholded Gene Set Scoring
Nov 13, 2022
Latch Verified Bulk-RNA Seq toolkit: a cloud-based suite of workflows for bulk RNA-seq quality control, analysis, and functional enrichment
Nov 13, 2022
DeepCCI: a deep learning framework for identifying cell-cell interactions from single-cell RNA sequencing data
Nov 13, 2022
GlyLES: Grammar-based Parsing of Glycans from IUPAC-condensed to SMILES
Nov 13, 2022
tFold-Ab: Fast and Accurate Antibody Structure Prediction without Sequence Homologs
Nov 13, 2022
INSIDER: Interpretable Sparse Matrix Decomposition for Bulk RNA Expression Data Analysis
Nov 13, 2022
Genebank genomics allows greatly improved taxonomic correction for Capsicum spp. accessions using a novel automated classification method
Nov 10, 2022
PAST: latent feature extraction with a Prior-based self-Attention framework for Spatial Transcriptomics
Nov 10, 2022
Massive proteogenomic reanalysis of publicly available proteomic datasets of human tissues in search for protein recoding via adenosine-to-inosine RNA editing
Nov 10, 2022
memento: Generalized differential expression analysis of single-cell RNA-seq with method of moments estimation and efficient resampling
Nov 10, 2022
Jointly aligning cells and genomic features of single-cell multi-omics data with co-optimal transport
Nov 10, 2022
Destin2: integrative and cross-modality analysis of single-cell chromatin accessibility data
Nov 10, 2022
Hybran: Hybrid Reference Transfer and ab initio Prokaryotic Genome Annotation
Nov 10, 2022
Accurate Detection of Incomplete Lineage Sorting via Supervised Machine Learning
Nov 10, 2022
Ibex: Variational autoencoder for single-cell BCR sequencing.
Nov 10, 2022
Reliable and accurate gene expression quantification with subpopulation structure-aware constraints for single-cell RNA sequencing
Nov 09, 2022
Pipeline for transferring annotations between proteins beyond globular domains
Nov 09, 2022
RBPamp: Quantitative Modeling of Protein-RNA Interactions in vitro Predicts in vivo Binding
Nov 09, 2022
dipwmsearch: a python package for searching di-PWM motifs
Nov 09, 2022
The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from Males
Nov 09, 2022
Technical Note: STRATIS: A Cloud-enabled Software Toolbox for Radiotherapy and Imaging Analysis
Nov 09, 2022
PathExpSurv: Pathway Expansion for Explainable Survival Analysis and Disease Gene Discovery
Nov 09, 2022
Geneplot: a coordinate conversion approach for graphical representation of protein domain data on the exon-intron structure of a gene.
Nov 09, 2022
Combined promoter-capture Hi-C and Hi-C analysis reveals a fine-tuned regulation of 3D chromatin architecture in colorectal cancer
Nov 09, 2022
SSB toolkit: from molecular structure to subcellular signaling pathways.
Nov 09, 2022
scmTE: multivariate transfer entropy builds interpretable compact gene regulatory networks by reducing false predictions
Nov 09, 2022
Challenges in antibody structure prediction
Nov 09, 2022
Cerebellar granule neurons induce Cyclin D1 in an early stage of Huntington's disease
Nov 09, 2022
STAMarker: Determining spatial domain-specific variable genes with saliency maps in deep learning
Nov 08, 2022
Single-cell imaging based prognosis prediction identifies new breast cancer survival subtypes
Nov 08, 2022
scAN10: A reproducible and standardized pipeline for processing 10X single cell RNAseq data
Nov 08, 2022
Adversarial Attacks on Genotype Sequences
Nov 08, 2022
An Approach to Identify Expression Quantitative Super Enhancers Using Single-cell Multi-omic Data
Nov 08, 2022
Structured Joint Decomposition (SJD) identifies conserved molecular dynamics across collections of biologically related multi-omics data matrices
Nov 08, 2022
GIL: A Python package for designing custom indexing primers
Nov 08, 2022
eccDNA Atlas: a comprehensive resource of eccDNA catalog
Nov 08, 2022
A personal, reference quality, fully annotated genome from a Saudi individual
Nov 08, 2022
Linking Gene Expression to Clinical Outcomes in Pediatric Crohn's Disease Using Machine Learning
Nov 08, 2022
Normalized Semi-Covariance Co-Efficiency Analysis of Spike Proteins from SARS-CoV-2 variant Omicron and Other Coronaviruses for their Infectivity and Virulence
Nov 08, 2022
PIQUE: An ImageJ plugin for the quantification of toroidal nuclei in biological images
Nov 07, 2022
Enrichment of charge-absent regions in phase separated proteins
Nov 06, 2022
An integrated Bayesian framework for multi-omics prediction and classification
Nov 06, 2022
mimicINT: a workflow for microbe-host protein interaction inference
Nov 06, 2022
Identification of Potential DNA Gyrase Inhibitors: Virtual Screening, Extra-Precision Docking and Molecular Dynamics Simulation Study
Nov 06, 2022
Learning predictive models of tissue cellular neighborhoods from cell phenotypes with graph pooling
Nov 06, 2022
Deep unfolded convolutional dictionary learning for motif discovery
Nov 06, 2022
Transcriptome Data Analysis of Primary Cardiomyopathies Reveals Perturbations in Arachidonic Acid Metabolism
Nov 06, 2022
Deep Learning-based Feature Extraction with MRI Data in Neuroimaging Genetics for Alzheimer's Disease
Nov 05, 2022
MetaGraph-MLA: Label-guided alignment to variable-order De Bruijn graphs
Nov 05, 2022
Deciphering tumor ecosystems at super-resolution from spatial transcriptomics with TESLA
Nov 05, 2022
WarpSTR: Determining tandem repeat lengths using raw nanopore signals
Nov 05, 2022
MethylSeqLogo: DNA methylation smart sequence logos
Nov 05, 2022
Improving annotation propagation on molecular networks through random walks: Introducing ChemWalker
Nov 05, 2022
Decipher macrophage-fibroblast-cardiomyocyte signaling interactions associated with heart failure using deep graph neural network models and single-cell RNA-seq data
Nov 04, 2022
Contrasting drugs from decoys
Nov 04, 2022
Cellpanelr: identify predictive biomarkers from cell line panel response data
Nov 04, 2022
END-TO-END CLASSIFICATION OF CELL-CYCLE STAGES WITH CENTER-CELL FOCUS TRACKER USING RECURRENT NEURAL NETWORKS
Nov 04, 2022
A Web/Cloud based Digital Pathology Platform Framework for AI Development and Deployment
Nov 04, 2022
Evolution-inspired augmentations improve deep learning for regulatory genomics
Nov 04, 2022
Machine-learning based detection of adventitious microbes in T-cell therapy cultures using long read sequencing
Nov 04, 2022
Adapting protein language models for rapid DTI prediction
Nov 04, 2022
A graph clustering algorithm for detection and genotyping of structural variants from long reads
Nov 04, 2022
Ensemble Clustering Combined with Clustering Optimization: A Novel Workflow for Analyzing Metabolomics Data
Nov 04, 2022
TCR_Explore: a novel webtool for T cell receptor repertoire analysis
Nov 04, 2022
SEPepQuant enables comprehensive protein isoform characterization in shotgun proteomics
Nov 04, 2022
kegg_pull: a Software Package for the RESTful Access and Pulling from The Kyoto Encyclopedia of Gene and Genomes
Nov 04, 2022
ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins.
Nov 04, 2022
An immune-suppressing protein in human endogenous retroviruses
Nov 04, 2022
EukRibo: a manually curated eukaryotic 18S rDNA reference database to facilitate identification of new diversity
Nov 04, 2022
DeepOM: Single-molecule optical genome mapping via deep learning
Nov 04, 2022
Integrated analysis of single-cell transcriptome of liver cancer and cirrhosis reveals cell lineage similarity and prognostic-associated subpopulations
Nov 04, 2022
Improving the Quality of Co-evolution Intermolecular Contact Prediction with DisVis
Nov 04, 2022
Mutual Annotation-Based Prediction of Protein Domain Functions with Domain2GO
Nov 04, 2022
ASCARIS: Positional Feature Annotation and Protein Structure-Based Representation of Single Amino Acid Variations
Nov 04, 2022
Towards increased accuracy and reproducibility in SARS-CoV-2 next generation sequence analysis for public health surveillance
Nov 03, 2022
IPLS-LDA: An Improved Partial Least Square Discriminant Analysis for Heterogeneous Transcriptomics and Metabolomics Data Analysis
Nov 03, 2022
TreeTerminus - Creating transcript trees using inferential replicate counts
Nov 03, 2022
Transcription is ubiquitously terminated in thousands of bidirectional termination zones in yeast
Nov 03, 2022
transmorph: a unifying computational framework for single-cell data integration
Nov 03, 2022
Sourmash Branchwater Enables Lightweight Petabyte-Scale Sequence Search
Nov 03, 2022
Sashimi.py: a flexible toolkit for combinatorial analysis of genomic data
Nov 03, 2022
Statistical analysis and simulation allowing simultaneously positive, negative, and no crossover interference in multilocus recombination data
Nov 03, 2022
Unraveling the coordinated dynamics of protein- and metabolite-mediated cell-cell communication
Nov 03, 2022
An information theoretic approach to detecting spatially varying genes
Nov 03, 2022
Gene model correction for PVRIG in single cell and bulk sequencing data enables accurate detection and study of its functional relevance
Nov 03, 2022
inMTSCCA: An Integrated Multi-task Sparse Canonical Correlation Analysis for Multi-omics Brain Imaging Genetics
Nov 02, 2022
Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods.
Nov 02, 2022
A comprehensive survey of long-range tertiary interactions and motifs in non-coding RNA structures
Nov 02, 2022
Singletrome: A method to analyze and enhance the transcriptome with long noncoding RNAs for single cell analysis
Nov 02, 2022
Filter inference: A scalable nonlinear mixed effects inference approach for snapshot time series data
Nov 02, 2022
HISS: Snakemake-based workflows for performing SMRT-RenSeq assembly, AgRenSeq and dRenSeq for the discovery of novel plant disease resistance genes.
Nov 02, 2022
Drug prediction for reversing AD/PD transcriptional profiles using an aging of systems-centric approach
Nov 02, 2022
KA-Search: Rapid and exhaustive sequence identity search of known antibodies
Nov 02, 2022
Improving quantitative structure models of trees inspired by pipe and metabolic scaling theory
Nov 01, 2022
Developing an automated skeletal phenotyping pipeline to leverage biobank-level medical imaging databases
Nov 01, 2022
Hypothesis-driven modeling of the human lung-ventilator system for Acute Respiratory Distress Syndrome research
Nov 01, 2022
Negligible peptidome diversity of SARS-CoV-2 and its higher taxonomic ranks
Nov 01, 2022
Falign: An effective alignment tool for long noisy 3C data
Nov 01, 2022
STREAMLINE: Structural and TopologicalPerformance Analysis of Algorithms for the Inference of Gene Regulatory Networks from Single-Cell Transcriptomic Data
Nov 01, 2022
A representative Performance Assessment of Maximum Likelihood based Phylogenetic Inference Tools
Nov 01, 2022
Best Practices for Interpretable Machine Learning in Computational Biology
Nov 01, 2022
ALaSCA: a computational platform for quantifying the effect of proteins using Pearlian causal inference, with an example application in Alzheimer's disease
Nov 01, 2022
Cooltools: enabling high-resolution Hi-C analysis in Python
Nov 01, 2022
PointVS: A Machine Learning Scoring Function that Identifies Important Binding Interactions
Oct 31, 2022
Transformer-based deep learning integrates multi-omic data with cancer pathways
Oct 31, 2022
Toblerone: detecting exon deletion events in cancer using RNA-seq
Oct 31, 2022
Identifying endogenous peptide receptors bycombining structure and transmembrane topologyprediction
Oct 31, 2022
One-stop analysis of DIA proteomics data using MSFragger-DIA and FragPipe computational platform
Oct 31, 2022
Expanding the stdpopsim species catalog, and lessons learned forrealistic genome simulations
Oct 31, 2022
Deep Learning vs Gradient Boosting in age prediction on immunology profile
Oct 31, 2022
Mining impactful discoveries from the biomedical literature
Oct 30, 2022
The BRAIN Initiative Cell Census Data Ecosystem: A User's Guide
Oct 30, 2022
Spectrum preserving tilings enable sparse and modular reference indexing
Oct 28, 2022
SalienceNet: an unsupervised Image-to-Image translation method for nuclei saliency enhancement in microscopy images
Oct 28, 2022
uORF4u: a tool for annotation of conserved upstream open reading frames
Oct 28, 2022
RecGraph: adding recombinations to sequence-to-graph alignments
Oct 28, 2022
Impact evaluation of score classes and annotation regions in deep learning-based dairy cow body condition prediction
Oct 28, 2022
Benchmarking solutions to the T-cell receptor epitope prediction problem: IMMREP22 workshop report
Oct 28, 2022
GENLIB: new function to simulate haplotype transmission in large complex genealogies
Oct 28, 2022
SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for prior-informed assessment of muscle function and pathology
Oct 28, 2022
Assessing the impacts of various factors related to identification, conservation, biogenesis, and function on circular RNA reliability
Oct 28, 2022
Quantitative analysis of cellular morphology during in vitro decidualization
Oct 28, 2022
Comparing 10x Genomics single-cell 3' and 5' assay in short-and long-read sequencing
Oct 28, 2022
Flux estimation analysis systematically characterizes the metabolic shifts of the central metabolism pathway in human cancer.
Oct 28, 2022
Identifying Neuropsychiatric Disorder Subtypes and Subtype-dependent Variation in Diagnostic Deep Learning Classifier Performance
Oct 28, 2022
Gait speed and individual characteristics can be used to predict specific gait metric magnitudes in neurotypical adults.
Oct 28, 2022
Modification of Seurat v4 for the development of a phase assignment tool able to distinguish between G2 and Mitotic cells
Oct 27, 2022
Statistical analysis supports pervasive RNA subcellular localization and alternative 3' UTR regulation
Oct 27, 2022
A Spectral Method for Assessing and Combining Multiple Data Visualizations
Oct 27, 2022
Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
Oct 27, 2022
BATCH-SCAMPP: Scaling phylogenetic placement methods to place many sequences
Oct 27, 2022
NanoBlot: A Simple Tool for Visualization of RNA Isoform Usage From Third Generation RNA-sequencing Data
Oct 27, 2022
A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis
Oct 27, 2022
IntestLine: a Shiny-based application to map the rolled intestinal tissue onto a line
Oct 27, 2022
Aligning Distant Sequences to Graphs using Long Seed Sketches
Oct 27, 2022
Statistically Consistent Rooting of Species Trees under the Multi-Species Coalescent Model
Oct 27, 2022
A Robust Bayesian Approach to Bulk Gene Expression Deconvolution withNoisy Reference Signatures
Oct 27, 2022
AI-Enabled Classification of Head and Neck Tumors using Convolutional Neural Networks with Dynamic Optical Contrast Imaging
Oct 27, 2022
A Unified Modular Framework to Incorporate Structural Dependency in Spatial Omics Data
Oct 27, 2022
T1K: efficient and accurate KIR and HLA genotyping with next-generation sequencing data
Oct 27, 2022
Assessing SARS-CoV-2 evolution through the analysis of emerging mutations
Oct 26, 2022
PEGG: A computational pipeline for rapid design of prime editing guide RNAs and sensor libraries
Oct 26, 2022
Technical report on best practices for hybrid and long read de novo assembly of bacterial genomes utilizing Illumina and Oxford Nanopore Technologies reads
Oct 26, 2022
SurvivalML: an integrative platform for the discovery and exploration of prognostic models in multi-center cancer cohorts
Oct 26, 2022
mutscan - a flexible R package for efficient end-to-end analysis of multiplexed assays of variant effect data
Oct 26, 2022
Ultra-fast joint-genotyping with SparkGOR
Oct 26, 2022
The geometry of hidden representations of protein language models
Oct 26, 2022
EUGENe: A Python toolkit for predictive analyses of regulatory sequences
Oct 26, 2022
Eliminate false positives in metagenomic profiling based on type IIB restriction sites
Oct 25, 2022
Cell Painting transfer increases screening hit rate
Oct 25, 2022
Regulation of cytoplasmic mRNA level by chromatin retention
Oct 25, 2022
meTCRs - Learning a metric for T-cell receptors
Oct 25, 2022
Transcriptome analyses using regulon, functional category, and operon information with GINtool
Oct 25, 2022
Comprehensive integration of single-cell transcriptomic data illuminates the regulatory network architecture of plant cell fate specification
Oct 25, 2022
Fever temperatures modulate intraprotein dynamics and enhance the binding affinity between monoclonal antibodies and the Spike protein from SARS-CoV-2
Oct 25, 2022
ISPRED-SEQ: Deep neural networks and embeddings for predicting interaction sites in protein sequences.
Oct 25, 2022
NDEx IQuery: a multi-method network gene set analysis leveraging the Network Data Exchange
Oct 25, 2022
Accurate de novo prediction of RNA 3D structure with transformer network
Oct 25, 2022
A scalable, reproducible and open-source pipeline for morphologically profiling image cytometry data
Oct 25, 2022
Adversarial Attacks on Protein Language Models
Oct 25, 2022
SDRAP for annotating scrambled or rearranged genomes
Oct 25, 2022
DeepSelectNet: Deep Neural Network Based Selective Sequencing for Oxford Nanopore Sequencing
Oct 25, 2022
Extremely-fast construction and querying of compacted and colored de Bruijn graphs with GGCAT
Oct 25, 2022
scifAI: Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies
Oct 25, 2022
Single-cell gene set enrichment analysis and transfer learning for functional annotation of scRNA-seq data
Oct 25, 2022
COOBoostR: an extreme gradient boosting-based tool for robust tissue or cell-of-origin prediction of tumors
Oct 25, 2022
The Molecular Signatures Database Revisited: Extending Support for Mouse Data
Oct 25, 2022
hgtseq: a standard pipeline to study horizontal gene transfer
Oct 25, 2022
MdrDB: Mutation-induced drug resistance DataBase
Oct 24, 2022
scCobra: Contrastive cell embedding learning with domain adaptation for single-cell data integration
Oct 24, 2022
MAVISp: Multi-layered Assessment of VarIants by Structure for proteins
Oct 24, 2022
Improving fine-mapping by modeling infinitesimal effects
Oct 24, 2022
Unsupervised Discovery of Ancestry Informative Markers and Genetic Admixture Proportions in Biobank-Scale Data Sets
Oct 24, 2022
Real-time detection of acute lymphoblastic leukemia cells using deep learning
Oct 24, 2022
Improving classification of correct and incorrect protein-protein docking models by augmenting the training set
Oct 24, 2022
SUsPECT: A pipeline for variant effect prediction based on custom long-read transcriptomes for improved clinical variant annotation
Oct 24, 2022
A positive statistical benchmark to assess network agreement
Oct 24, 2022
KBeagle: An Adaptive Strategy and Tool for Improvement of Imputation Accuracy and Computing Efficiency
Oct 24, 2022
Optimal microRNA sequencing depth to predict cancer patient survival with random forest and Cox models
Oct 24, 2022
GiRAFR improves gRNA detection and annotation in single cell CRISPR screens
Oct 24, 2022
ViReaDB: A user-friendly database for compactly storing viral sequence data and rapidly computing consensus genome sequences
Oct 24, 2022
Genome-wide identification and analysis of analysis of BURP genes in Triticum aestivum
Oct 24, 2022
ACDA: Implementation of an Augmented Drug Synergy Prediction Algorithm
Oct 22, 2022
MSBooster: Improving Peptide Identification Rates using Deep Learning-Based Features
Oct 21, 2022
Graph Regularized Probabilistic MatrixFactorization for Drug-Drug Interactions Prediction
Oct 21, 2022
DANCE: A Deep Learning Library and Benchmark for Single-Cell Analysis
Oct 21, 2022
MAW - The Reproducible Metabolome Annotation Workflow for Untargeted Tandem Mass Spectrometry
Oct 21, 2022
Discovery of gene-gene co-perturbation through big data
Oct 21, 2022
Towards Hierarchical Causal Representation Learning for Nonstationary Multi-Omics Data
Oct 21, 2022
DGH-GO: Dissecting the Genetic Heterogeneity of complex diseases using Gene Ontology
Oct 21, 2022
Census: accurate, automated, deep, fast, and hierarchical scRNA-seq cell-type annotation
Oct 21, 2022
TF-Prioritizer: a java pipeline to prioritize condition-specific transcription factors
Oct 21, 2022
Efficient minimizer orders for large values of k using minimum decycling sets
Oct 21, 2022
Vector-clustering Multiple Sequence Alignment: Aligning into the twilight zone of protein sequence similarity with protein language models
Oct 21, 2022
A Platform-Independent Framework for Phenotyping of Multiplex Tissue Imaging Data
Oct 21, 2022
Some Mendelian Disorders could be fixed with a pill? A Structural Bioinformatic investigation
Oct 21, 2022
Multi-histone ChIP-Seq Analysis with DecoDen
Oct 21, 2022
Prediction and scanning of IL-5 inducing peptides using alignment-free and alignment-based method
Oct 21, 2022
MorphNet Predicts Cell Morphology from Single-Cell Gene Expression
Oct 21, 2022
Insitutype: likelihood-based cell typing for single cell spatial transcriptomics
Oct 21, 2022
Pathway-informed deep learning model for survivalanalysis and pathological classification of gliomas
Oct 21, 2022
Performance Evaluation Of Prediction On Molecular Graphs With Graph Neural Networks
Oct 21, 2022
Identification of RNA-based cell-type markers for the stem cell manufacture system with a statistical scoring function
Oct 21, 2022
VStrains: De Novo Reconstruction of Viral Strains via Iterative Path Extraction From Assembly Graphs
Oct 21, 2022
Repurposing of Drugs against mutated strain of Eurasian Avian like H1N1 (EA H1N1) Swine flu, Genotype-4 (G4) virus
Oct 21, 2022
The GEN-ERA toolbox: unified and reproducible workflows for research in microbial genomics .
Oct 21, 2022
NEMETEX: a Python software for the visualisation of the network of metabolic exchanges
Oct 21, 2022
Retention time prediction to facilitate molecularstructure identification with tandem mass spectrometry
Oct 21, 2022
Predicting individualized tissue gene expression profiles with multi-task learning
Oct 21, 2022
TEINet: a deep learning framework for prediction of TCR-epitope binding specificity
Oct 21, 2022
DeepChIA-PET: Accurately predicting ChIA-PET from Hi-C and ChIP-seq with deep dilated networks
Oct 21, 2022
GSearch: Ultra-Fast and Scalable Microbial Genome Search by combining Kmer Hashing with Hierarchical Navigable Small World Graphs
Oct 21, 2022