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Episodes: 1568

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Audio versions of bioRxiv and medRxiv paper abstracts

Episode Date
Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation.
Aug 05, 2023
Super-resolution optical imaging reveals accumulation of small mitochondria in the nucleoli of mouse embryos and stem cells
Aug 05, 2023
A fibroblast-derived TGFβ/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis
Aug 05, 2023
Cell growth and nutrient availability control the mitotic exit signaling network in budding yeast
Aug 04, 2023
Tight junction membrane proteins regulate the mechanical resistance of the apical junctional complex
Aug 04, 2023
The mechanics of bronchoconstriction cause airway epithelial damage and inflammation by excess crowding-induced extrusion
Aug 04, 2023
RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis
Aug 04, 2023
Optogenetic control of lysosome function
Aug 04, 2023
Multi-color live-cell optical nanoscopy using phasor analysis
Aug 04, 2023
Positive feedback regulation of Pparγ1sv and Pparγ2 during adipogenesis in 3T3-L1 cells
Aug 04, 2023
A force-sensitive mutation reveals a spindle assembly checkpoint-independent role for dynein in anaphase progression
Aug 04, 2023
FAM210A mediates an inter-organelle crosstalk essential for protein synthesis and muscle growth in mouse
Aug 04, 2023
Aggregation of Disrupted in Schizophrenia 1 arises from a central region of the protein
Aug 04, 2023
Recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2
Aug 04, 2023
A Bright, Photostable Dye that Enables Multicolor, Time Lapse, and Super-Resolution Imaging of Acidic Organelles
Aug 04, 2023
Oligomerization and feedback on membrane recruitment stabilize PAR-3 asymmetries in C. elegans zygotes.
Aug 04, 2023
Determining the structure of protein-bound ceramides, essential lipids for skin barrier function
Aug 04, 2023
Correlative single-cell X-ray tomography and X-ray fluorescence imaging
Aug 04, 2023
Discovery of a multipotent cell type from the term human placenta
Aug 04, 2023
Parallel proteomics and phosphoproteomics defines starvation signal specific processes in cell quiescence
Aug 04, 2023
Diverse mechanisms control amino acid-dependent environmental alkalization by Candida albicans
Aug 04, 2023
Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells
Aug 04, 2023
Sulfolobus acidocaldarius adhesion pili power twitching motility in the absence of a dedicated retraction ATPase
Aug 04, 2023
Lactate activates the mitochondrial electron transport chain independent of its metabolism
Aug 04, 2023
Comprehensive genome editing confers "off-the-shelf" CAR-T cells superior efficacy against solid tumors
Aug 04, 2023
hGRAD - a versatile 'one-fits-all' system for the acute depletion of RNA binding proteins in nuclear condensates
Aug 04, 2023
Presence of the ER-Golgi intermediate compartment that matures into the Golgi in yeast
Aug 03, 2023
Inhibition of Topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats
Aug 03, 2023
Lysosomal release of amino acids at ER three-way junctions regulates transmembrane and secretory protein mRNA translation
Aug 03, 2023
Immunoregulatory macrophages modify local pulmonary immunity and ameliorate hypoxic-pulmonary hypertension
Aug 03, 2023
Chaperone Complexes From The Endoplasmic Reticulum (ER) And The Cytosol Inhibit wt-p53 By Activation The ER To Cytosol Signaling.
Aug 03, 2023
Discretised flux balance analysis for reaction-diffusion simulation of single-cell metabolism
Aug 03, 2023
IST1 regulates select endosomal recycling pathways
Aug 02, 2023
The ciliary MBO2 complex targets assembly of inner arm dynein b and reveals additional doublet microtubule asymmetries
Aug 02, 2023
The Crk4-Cyc4 complex regulates G2 phase of apicomplexan endodyogeny
Aug 02, 2023
Myogenetic oligodeoxynucleotide induces myocardial differentiation of murine pluripotent stem cells
Aug 02, 2023
Disordered C-terminal domain drives spatiotemporal confinement of RNAPII to enhance search for chromatin targets
Aug 02, 2023
Dynamic proximity interaction profiling suggests that YPEL2 is involved in cellular stress surveillance
Aug 02, 2023
Induced pluripotent stem cell-derived human macrophages as an infection model for Leishmania donovani
Aug 02, 2023
Mitochondrial Ca2+ uniporter (MCU) variants form plasma-membrane channels
Aug 02, 2023
Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
Aug 02, 2023
Growth-dependent concentration gradient of the oscillating Min system in Escherichia coli
Aug 02, 2023
Single-cell and spatial transcriptomics reveals the human liver immunological landscape and myeloid dysfunction in PSC.
Aug 01, 2023
Therapeutic effect of dietary interventions on senescence in animals and humans: A systematic review
Aug 01, 2023
Nanoscale analysis of human G1 and metaphase chromatin in situ
Jul 31, 2023
Long-chain fatty acyl-coenzyme A activates the mitochondrial fission factors MiD49 and MiD51 by inducing their oligomerization
Jul 31, 2023
Single tyrosine mutation in VE-cadherin modulates gene lung expressions: evidence for FOXF1 mediated S1PR1 upregulation to stabilize vessels in mice
Jul 31, 2023
Actin-Driven Nanotopography Enhances Integrin Molecular Clutch in Developing Tissue
Jul 30, 2023
DCLRE1B/hSNM1B (Apollo) is not acutely required for human pluripotent stem cell survival
Jul 30, 2023
Mutual dependence of Osbp and PI4KII in the maturation of regulated secretory granules
Jul 30, 2023
A mechanical modelling framework to study endothelial permeability
Jul 30, 2023
Evaluating cytotoxicity and genotoxicity of oil extracted from visceral fat of Caiman yacare (Daudin, 1802) in chinese hamster lung fibroblast in vitro.
Jul 30, 2023
Targeted Photoconvertible BODIPYs Based on Directed Photooxidation Induced Conversion for Applications in Photoconversion and Live Super Resolution Imaging
Jul 30, 2023
Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in hepatic stellate cells
Jul 30, 2023
Distinct human stem cell subpopulations drive adipogenesis and fibrosis in musculoskeletal injury
Jul 29, 2023
Epigenetic modifications driving ground state pluripotency exit require an NF-κB-independent chromatin IκBα function
Jul 29, 2023
Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions
Jul 29, 2023
Unbiased method for spectral analysis of cells with great diversity of autofluorescence spectra
Jul 29, 2023
Neuroprotective role of lactate in a human in vitro model of the ischemic penumbra
Jul 29, 2023
Rho-associated kinase regulates Langerhans cell morphology and responsiveness to tissue damage
Jul 29, 2023
Enhancing gene transfer to renal tubules and podocytes by context-dependent selection of AAV capsids
Jul 29, 2023
An adaptive biomolecular condensation response is conserved across environmentally divergent species
Jul 29, 2023
Microtubule association of TRIM3 revealed by differential extraction proteomics
Jul 28, 2023
A new mechanism of posttranslational polyglutamylation regulates phase separation and signaling of the Wnt pathway protein Dishevelled.
Jul 28, 2023
Universal length fluctuations of actin structures found in cells
Jul 28, 2023
Human receptive endometrial organoid for deciphering the implantation window
Jul 28, 2023
Ribosomal Protein SA (RPSA) is required for localized translation and sarcomere maintenance
Jul 28, 2023
The nuclei of human adult stem cells can move within the cell and generate cellular protrusions to contact other cells
Jul 27, 2023
The membrane-actin linkers ezrin, radixin, and moesin are dispensable for macrophage migration and cortex mechanics.
Jul 27, 2023
Disease-associated gut microbiome and metabolome changes in chronic low back pain patients with bone marrow lesions
Jul 27, 2023
Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Jul 27, 2023
RAD54L regulates replication fork progression and nascent strand degradation in BRCA1/2-deficient cells
Jul 27, 2023
Megakaryocyte maturation involves activation of the IRE1α-dependent adaptive unfolded protein response
Jul 27, 2023
Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
Jul 27, 2023
Downregulation of lysosomal trafficking in ARPE19 cells leads to decreased transfection efficiency at high passage
Jul 27, 2023
Apical annuli are specialised sites of post-invasion secretion of dense granules in Toxoplasma
Jul 27, 2023
Beyond 40 fluorescent probes for deep phenotyping of blood mononuclear cells, using spectral technology.
Jul 27, 2023
IF1 controls UCP1-dependent mitochondrial bioenergetics in brown adipocytes
Jul 27, 2023
Leishmania major-induced alteration of host cellular and systemic copper homeostasis drives the fate of infection
Jul 26, 2023
Primary human lung fibroblasts exhibit trigger- but not disease-specific cellular senescence and impair alveolar epithelial cell progenitor function
Jul 26, 2023
The maintenance of centriole appendages and motile cilia basal body anchoring relies on TBCCD1
Jul 26, 2023
The use of imaging flow cytometry for rapid, high-throughput and automated analysis of the Leishmania mexicana promastigote cell cycle provides new insights into cell cycle events of short duration
Jul 25, 2023
Novel centriolar defects underlie a primary ciliary dyskinesia phenotype in adenylate kinase 7 deficient ciliated epithelium.
Jul 25, 2023
FAM104 proteins promote the nuclear localization of p97/VCP
Jul 25, 2023
The Hippo kinase cascade regulates a contractile cell behavior and cell density in a close unicellular relative of animals
Jul 25, 2023
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors
Jul 25, 2023
TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cells
Jul 25, 2023
pHusion: A robust and versatile toolset for automated detection and analysis of exocytosis
Jul 25, 2023
Mechano-dependent sorbitol accumulation supports biomolecular condensate
Jul 25, 2023
Collective dynamics of formin and microtubule and its crosstalk mediated by FHDC1
Jul 25, 2023
The Arf-GAP Age2 localizes to the late-Golgi via a conserved amphipathic helix
Jul 24, 2023
Evolution of cullin E3 ubiquitin ligases and function in trypanosomes
Jul 24, 2023
Downregulation of a cell polarity protein potentiates Chikungunya Virus infection in host cells
Jul 24, 2023
Characterization of Pik1 function in fission yeast reveals its conserved role in lipid synthesis and not cytokinesis
Jul 24, 2023
Coronin-1 controls directional cell rearrangement in Drosophila wing epithelium
Jul 24, 2023
Mecp2 Fine-tunes Quiescence Exit by Targeting Nuclear Receptors
Jul 24, 2023
SCN9A gene therapy: Novel mechanism to inhibit cellular senescence in astrocytes in vitro
Jul 24, 2023
A genome-wide single-cell 3D genome atlas of lung cancer progression
Jul 24, 2023
MiniBAR/KIAA0355 is a dual Rac and Rab effector required for ciliogenesis
Jul 24, 2023
Metabolomic rearrangement controls the intrinsic microbial response to temperature changes
Jul 24, 2023
Endocytic vesicles act as vehicles for glucose uptake in response to growth factor stimulation
Jul 24, 2023
Essential role of the CCL2-CCR2 axis in Mayaro virus-induced disease
Jul 24, 2023
Regulation of mitochondrial calcium uniporter expression and calcium signalling by lncRNA Tug1 in cardiomyocytes.
Jul 24, 2023
Dynamic regulatory phosphorylation of mouse CDK2 occurs during meiotic prophase I
Jul 24, 2023
Helical motors and formins synergize to compact chiral filopodial bundles: a theoretical perspective.
Jul 24, 2023
Resolution enhancement with deblurring by pixel reassignment (DPR)
Jul 24, 2023
The Role of the Tyrosine-Based Sorting Signals of the ORF3a Protein of SARS-CoV-2 on Intracellular Trafficking, Autophagy, and Apoptosis
Jul 24, 2023
An mTOR/RNA pol I axis shapes chromatin architecture in response to fasting
Jul 22, 2023
Extracting herbicide and antibiotic natural products from a plant-microbe interaction system
Jul 22, 2023
ISGylation-independent protection of cell growth by USP18 following interferon stimulation
Jul 21, 2023
Generation of an induced pluripotent stem cell line from a healthy adult indigenous Nigerian participant
Jul 21, 2023
The interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking
Jul 21, 2023
Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing
Jul 21, 2023
Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival
Jul 21, 2023
Dual regulation of Misshapen by Tao and Rap2l promotes collective cell migration
Jul 21, 2023
Enucleation of the C. elegans embryo revealed the mechanism of dynein-dependent spacing between microtubule asters
Jul 21, 2023
Identification and Characterization of Calcium Binding Protein, Spermatid Associated 1 (CABS1) in Selected Human Tissues and Fluids
Jul 21, 2023
Transcription factor-mediated direct cellular reprogramming yields cell-type specific DNA methylation signature
Jul 21, 2023
Validation of GCN5L1/BLOC1S1/BLOS1 Antibodies Using Knockout Cells and Tissue
Jul 21, 2023
Autophagy maintains the homeostatic environment in the male reproductive accessory organs playing a key role in fertility
Jul 21, 2023
Spatiotemporal precise optical manipulation of intracellular molecular activities
Jul 20, 2023
A molecular toolbox to study progesterone receptor signaling
Jul 20, 2023
AMPK targets PDZD8 to trigger carbon source shift to glutamine
Jul 20, 2023
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring
Jul 20, 2023
Post-translational regulation of the Numb/Notch pathway in neurogenesis and cancer by Dlk2
Jul 20, 2023
Continuous endosomes form functional subdomains and orchestrate rapid membrane trafficking in trypanosomes
Jul 20, 2023
Pancreatic islet cell stress induced by insulin-degrading enzyme deficiency promotes islet regeneration and protection from autoimmune diabetes
Jul 20, 2023
Bioactive effects of natural and novel unnatural tropolone sesquiterpenoids in a murine cell model of renal interstitial fibroblasts
Jul 19, 2023
Dynamics of pax7 expression during development, muscle regeneration, and in vitro differentiation of satellite cells in the trout.
Jul 19, 2023
High resolution spatial investigation of intracellular oxygen in muscle cells.
Jul 19, 2023
Effects of Alternative Splicing-Specific Knockdown of Tjp1 α+ by Rbm47 on Tight Junctions Assembly during Blastocyst Development
Jul 19, 2023
Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP-A
Jul 19, 2023
The cellular landscape of the endochondral bone highlights its multipotent and immunomodulatory features during the transition to extrauterine life
Jul 19, 2023
Single cell RNA analysis uncovers the cell differentiation trajectories and functionalization for air breathing of frog lung
Jul 19, 2023
Cold temperature induces a TRPM8-independent calcium release from the endoplasmic reticulum in human platelets
Jul 19, 2023
Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth
Jul 19, 2023
A Plant Flavonol Rescues a Pathogenic Mutation Associated with Kinesin in Neurons
Jul 19, 2023
Cardiomyocyte mechanical memory is regulated through the talin interactome and DLC1 dependent regulation of RhoA
Jul 19, 2023
Perturbations of glutathione and sphingosine metabolites in Port Wine Birthmark patient-derived induced pluripotent stem cells
Jul 19, 2023
Analysis of Drosophila and mouse mutants reveals that Peroxidasin is required for tissue mechanics and full viability
Jul 19, 2023
A signalling rheostat controls chromosome segregation fidelity during early lineage specification and neurogenesis by modulating DNA replication stress
Jul 18, 2023
S100A11 promotes focal adhesion disassembly via myosin II-driven contractility and Piezo1-mediated Ca2+ entry
Jul 18, 2023
ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin
Jul 18, 2023
Non-cell autonomous cardiomyocyte regulation complicates gene supplementation therapy for LMNA cardiomyopathy
Jul 18, 2023
Cell networks in the mouse liver during partial hepatectomy
Jul 18, 2023
Monitoring hPSC genomic stability in the chromosome 20q region by ddPCR
Jul 18, 2023
Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery
Jul 18, 2023
Three-step docking by WIPI2, ATG16L1 and ATG3 delivers LC3 to the phagophore
Jul 17, 2023
Multi-monoubiquitination controls VASP-mediated actin dynamics
Jul 17, 2023
Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization
Jul 16, 2023
Loss of Progranulin Results in Increased Pan-Cathepsin Activity and Reduced LAMP1 Lysosomal Protein
Jul 16, 2023
From Pixels to Phenotypes: Integrating Image-Based Profiling with Cell Health Data Improves Interpretability
Jul 16, 2023
Ubiquitination-mediated Golgi-to-endosome sorting determines the poison-antidote duality of wtf meiotic drivers
Jul 16, 2023
Refrigerated storage and cryopreservation of hormone induced sperm in a threatened frog
Jul 16, 2023
Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton
Jul 16, 2023
Cryo-electron tomography of eel sperm flagella reveals a molecular "minimum system" for motile cilia
Jul 16, 2023
Cardiomyocyte-specific adenylyl cyclase type-8 overexpression induces cell-autonomous activation of RelA and non-cell-autonomous myocardial and systemic inflammation
Jul 16, 2023
Role of trafficking protein particle complex 2 in medaka development
Jul 14, 2023
Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics
Jul 14, 2023
Changes in cell morphology and function induced by NRAS Q61R mutation in lymphatic endothelial cells
Jul 14, 2023
Polyubiquitinated PCNA promotes alternative lengthening of telomeres by inducing break-induced replication
Jul 14, 2023
DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization
Jul 14, 2023
Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses
Jul 14, 2023
Trafficking Machinery is Rapidly Primed to Facilitate Polarised IL-6 Secretion in Dendritic Cells
Jul 13, 2023
A Size Filter Regulates Apical Protein Sorting
Jul 13, 2023
Treatment of advanced atherosclerotic mice with the senolytic agent ABT-263 is associated with reduced indices of plaque stability and increased mortality
Jul 13, 2023
Unlocking the Role of Endothelial MPL Receptor and JAK2V617F Mutation: Insights into Cardiovascular Dysfunction in MPNs and CHIP
Jul 13, 2023
Multiple genetic variants at the SLC30A8 locus affect a local super-enhancer cluster to influence pancreatic β-cell survival and function
Jul 13, 2023
Eye lens organoids going simple: characterization of a new 3-dimensional organoid model for lens development and pathology
Jul 12, 2023
The Septin Cytoskeleton is Required for Plasma Membrane Repair
Jul 12, 2023
Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport
Jul 12, 2023
BNIP3-mediated mitophagy boosts the competitive dominant growth of lenvatinib resistant cells via reprogramming energy metabolism in HCC
Jul 12, 2023
EMDiffuse: a diffusion-based deep learning method augmenting ultrastructural imaging and volume electron microscopy
Jul 12, 2023
Oncostatin M is a Master Regulator of an Inflammatory Network in Dnmt3a-Mutant Hematopoietic Stem Cells
Jul 12, 2023
Natural transformation specific DprA coordinate DNA double strand break repair pathways in heavily irradiated D. radiodurans
Jul 12, 2023
Multi-tissue proteomics identifies a link between satellite DNA organization and transgenerational transposon repression in Drosophila
Jul 12, 2023
Endocytosis Inhibitors Block SARS-CoV-2 Pseudoparticle Infection of Mink Lung Epithelium
Jul 12, 2023
OrgaMapper: A robust and easy-to-use workflow for analyzing organelle positioning
Jul 11, 2023
Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix
Jul 11, 2023
Pathogenic aggregates alter actin organization and cellular viscosity resulting in stalled clathrin mediated endocytosis
Jul 11, 2023
Mitochondrial proteostasis mediated by CRL5Ozz and Alix maintains skeletal muscle function
Jul 11, 2023
Exportin-mediated nucleocytoplasmic transport maintains Pch2 homeostasis during meiosis
Jul 10, 2023
ZIF-1-mediated degradation of endogenous and heterologous zinc finger proteins in the C. elegans germ line
Jul 10, 2023
Remodeling of the secretory pathway is coordinated with de novo membrane formation in budding yeast gametogenesis
Jul 10, 2023
The Drosophila Tumour Suppressor Lgl and Vap33 activate the Hippo pathway by a dual mechanism, involving RtGEF/Git/Arf79F and inhibition of the V-ATPase.
Jul 10, 2023
miR-324 mediates bone homeostasis through the regulation of osteoblast and osteoclast differentiation and activity
Jul 10, 2023
An amino acid-resolution interactome for motile cilia illuminates the structure and function of ciliopathy protein complexes
Jul 10, 2023
Label-free ghost cytometry for manufacturing of cell therapy products
Jul 10, 2023
Spatial organization and function of RNA molecules within phase-separatedcondensates are controlled by Dnd1
Jul 09, 2023
ScaleFExSM: a lightweight and scalable method to extract fixed features from single cells in high-content imaging screens
Jul 09, 2023
Peripheral positioning of lysosomes supports melanoma aggressiveness
Jul 09, 2023
Mitochondrial-Derived Compartments Remove Surplus Proteins from the Outer Mitochondrial Membrane
Jul 08, 2023
Affinity hierarchies underlie the co-assembly of nucleolar and heterochromatin condensates in Drosophila embryos
Jul 08, 2023
Neuromorphic Cytometry: Implementation on cell counting and size estimation
Jul 07, 2023
Near infrared-light treatment alters mitochondrial homeostasis to induce senescence in breast cancer cells
Jul 07, 2023
Filter-aided extracellular vesicle enrichment (FAEVEr)
Jul 07, 2023
Activation of goblet cell stress sensor IRE1β is controlled by the mucin chaperone AGR2
Jul 07, 2023
A role for Vps13-mediated lipid transfer at the ER-endosome contact site in ESCRT-mediated sorting
Jul 07, 2023
Mon1a and FCHO2 are required for maintenance of Golgi architecture
Jul 07, 2023
Complex Sphingolipid Profiling and Identification of an Inositol Phosphorylceramide Synthase in Dictyostelium discoideum
Jul 07, 2023
Mitochondrial-Derived Compartments are Multilamellar Domains that Encase Membrane Cargo and Cytosol
Jul 07, 2023
Distinct structural motifs are necessary for targeting and import of Tim17 in Trypanosoma brucei mitochondrion
Jul 07, 2023
Nuclear envelope assembly relies on CHMP-7 in the absence of BAF-LEM-mediated hole closure
Jul 07, 2023
Aβ-aggregation-generated blue autofluorescence illuminates senile plaques, complex blood and vascular pathologies in the Alzheimer's disease
Jul 07, 2023
Augmented Super-Resolution Radial Fluctuations (aSRRF) Pushing the Limits of Structured Illumination Microscopy
Jul 06, 2023
Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness
Jul 05, 2023
Phosphorylation-dependent interactions of VAPB and ELYS contribute to the temporal progression of mitosis
Jul 05, 2023
Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm
Jul 05, 2023
Control of C. elegans growth arrest by stochastic, yet synchronized DAF-16/FOXO nuclear translocation pulses
Jul 05, 2023
Metabolism regulates muscle stem cell self-renewal by connecting the microenvironment and histone acetylation
Jul 05, 2023
A matrisome atlas of germ cell development
Jul 04, 2023
The longer the better: longer acrosomes contain more proteins involved in sperm-egg interactions
Jul 04, 2023
A scalable, data analytics workflow for image-based morphological profiles
Jul 04, 2023
CaaX-motif adjacent residues control G protein prenylation under suboptimal conditions
Jul 04, 2023
Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy
Jul 03, 2023
Effect of Aging on the Human Myometrium at Single-Cell Resolution
Jul 03, 2023
Establishing RNAge to score cellular aging and rejuvenation paradigms and identify novel age-modulating compounds
Jul 03, 2023
Dynein and dynactin move long-range but are delivered separately to the axon tip
Jul 03, 2023
Direct recruitment of Mis18 to interphase spindle poles promotes CENP-A chromatin assembly
Jul 03, 2023
Sub-lethal exposure to chlorfenapyr reduces the probability of developing Plasmodium falciparum parasites in surviving Anopheles mosquitoes
Jul 03, 2023
Novel phosphatidylinositol flippases contribute to phosphoinositide homeostasis in the plasma membrane
Jul 03, 2023
Diseased human pancreas and liver microphysiological system for preclinical diabetes research
Jul 03, 2023
Differential expression of tension-sensitive HOX genes in fibroblasts is associated with different scar types
Jul 03, 2023
Extracellular vesicles promote autophagy in human microglia through lipid raft-dependent mechanisms
Jul 03, 2023
ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims
Jul 02, 2023
Hippo and Wnt pathways are impaired in Port Wine Birthmark-derived induced pluripotent stem cells and endothelial cells
Jul 02, 2023
BRD4 directs mitotic cell division by inhibiting DNA damage
Jul 02, 2023
Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues.
Jul 02, 2023
Fusion of histone variants to Cas9 enhances homology-directed repair
Jul 02, 2023
A Serum- and Feeder-Free System to Generate CD4 and Regulatory T Cells from Human iPSCs
Jul 02, 2023
Mitigation of the effect of high light on the photosynthetic apparatus of Rhodobacter alkalitolerans when grown in an alkaline environment
Jul 01, 2023
The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies
Jul 01, 2023
Preferential transport of synaptic vesicles across neuronal branches is regulated by the levels of the anterograde motor UNC-104/KIF1A
Jul 01, 2023
Interaction between PSD 95 and TRPV4 through PDZ domain controls TRPV4's localization and activity.
Jul 01, 2023
Orchestration of differential mesodermal fate choice from ESCs by Wnt-USP3 link and H2A/H2B contextual deubiquitination.
Jul 01, 2023
Structural insights into dual-antagonize mechanism of AB928 on adenosine A2 receptors
Jul 01, 2023
The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix
Jun 30, 2023
Single cell-resolution in situ sequencing elucidates spatial dynamics of multiple sclerosis lesion and disease evolution
Jun 30, 2023
Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy
Jun 30, 2023
Mechanical coupling coordinates microtubule growth
Jun 30, 2023
Mechanistic constraints on the trade-off between photosynthesis and respiration in response to warming
Jun 30, 2023
Matrix stiffening promotes perinuclear clustering of mitochondria
Jun 30, 2023
Post-Transplant Administration of G-CSF Impedes Engraftment of Gene Edited Human Hematopoietic Stem Cells by Exacerbating the p53-Mediated DNA Damage Response
Jun 30, 2023
A partial Drp1 knockout improves autophagy flux independent of mitochondrial function
Jun 30, 2023
C-terminal amides mark proteins for degradation via SCF/FBXO31
Jun 30, 2023
TREX reveals proteins that bind to specific RNA regions in living cells
Jun 30, 2023
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication
Jun 30, 2023
Sse1, Hsp110 chaperone of yeast, controls the cellular fate during Endoplasmic Reticulum-stress
Jun 29, 2023
Proteins differentially expressed between pathogenic and non-pathogenic Entamoeba histolytica clones influence pathogenicity by different mechanisms
Jun 29, 2023
A rapid, inexpensive, non-lethal method for detecting disseminated neoplasia in a bivalve
Jun 29, 2023
Liver-specification of human iPSC-derived endothelial cells transplanted into mouse liver
Jun 29, 2023
Nuclear quality control of non-imported secretory proteins attenuates proteostasis decline in the cytosol
Jun 28, 2023
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.
Jun 28, 2023
p53 controls the nuclear entry and epigenetic modification of H3.1 by downregulating nuclear phosphatidic acid
Jun 28, 2023
The Tubulin Nano-Code: a protofilament-specific pattern of tubulin post-translational modifications regulates ciliary beating mechanics
Jun 28, 2023
Decline of DNA damage response along with myogenic differentiation
Jun 28, 2023
Identification of small molecule inhibitors of G3BP-driven stress granule formation
Jun 28, 2023
Self-extinguishing relay waves enable homeostaticcontrol of human neutrophil swarming
Jun 28, 2023
Synthetic autotetraploid Caenorhabditis elegans resist severe cold stress by escaping cold induced death at the gravid adult stage.
Jun 28, 2023
F-actin and Myosin F control apicoplast elongation dynamics which drive apicoplast-centrosome association in Toxoplasma gondii
Jun 28, 2023
SETDB1 modulates the TGFbeta response in Duchenne muscular dystrophy myotubes
Jun 28, 2023
Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies
Jun 28, 2023
Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair
Jun 26, 2023
The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes
Jun 26, 2023
Cellular endosomal potassium ion flux regulates arenavirus uncoating during virus entry
Jun 26, 2023
Hypoxia induced oxidative stress and endoplasmic reticulum stress promoted myocardial cell fibrosis
Jun 26, 2023
Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation
Jun 26, 2023
Histone chaperone HIRA, Promyelocytic Leukemia (PML) protein and p62/SQSTM1 coordinate to regulate inflammation during cell senescence and aging.
Jun 26, 2023
Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains
Jun 26, 2023
TECPR1 provides E3-ligase like activity to the ATG5-ATG12 complex to conjugate LC3/ATG8 to damaged lysosomes
Jun 26, 2023
Luminal transport rates through intact endoplasmic reticulum limit the magnitude of localized Ca2+ signals
Jun 26, 2023
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities
Jun 26, 2023
Study on Vibrational Behavior of Cytoskeletons Modeled by Cylindrical Tensegrity Structure
Jun 26, 2023
Differences in Hepatocellular Iron Metabolism Underlie Sexual Dimorphism in Hepatocyte Ferroptosis
Jun 26, 2023
TOMM40 and TOMM22 of the Translocase Outer Mitochondrial Membrane Complex rescue statin-impaired mitochondrial dynamics, morphology, and mitophagy in skeletal myotubes
Jun 26, 2023
Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen sensing pathways in mammalian cells
Jun 26, 2023
Specific prostaglandins are produced in the migratory cells and the surrounding substrate to promote Drosophila border cell migration
Jun 26, 2023
Glucose-stimulated KIF5B-driven microtubule sliding organizes microtubule networks in pancreatic beta cells
Jun 26, 2023
Vacuolar H+-ATPase Determines Daughter Cell Fates through Asymmetric Segregation of the Nucleosome Remodeling and Deacetylase Complex
Jun 26, 2023
Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB
Jun 26, 2023
SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss
Jun 26, 2023
Pushed to the edge: hundreds of myosin 10s pack into filopodia and could cause traffic jams on actin
Jun 26, 2023
Combinatorial selective ER-phagy remodels the ER during neurogenesis
Jun 26, 2023
Genetic Screen Identified Prmt5 as a Neuroprotection Target against Cerebral Ischemia
Jun 26, 2023
HD mutation results in a dominant negative effect on HTT function
Jun 26, 2023
Cytoplasmic redox imbalance in the thioredoxin system activates Hsf1 and results in hyperaccumulation of the sequestrase Hsp42 with misfolded proteins
Jun 26, 2023
Phenotypic Switching of Vascular Smooth Muscle Cells in Duchenne Muscular Dystrophy
Jun 25, 2023
The microenvironment dictates glycocalyx construction and immune surveillance
Jun 25, 2023
Piezo1 conspires with INF2 to promote amoeboid migration in confined environments
Jun 25, 2023
PINK1 Deficiency Alters Muscle Stem Cell Fate Decision And Muscle Regenerative Capacity.
Jun 25, 2023
Single-cell Transcriptomic Analysis of Salivary Gland Endothelial Cells
Jun 24, 2023
Periosteal response to bone fracture at single nuclei resolution
Jun 24, 2023
Cell swelling enhances GPCR ternary complex formation, underpinning the potentiation of beta2 adrenergic receptor-mediated cAMP response
Jun 24, 2023
WRNIP1 prevents transcription-associated genomic instability
Jun 24, 2023
Epithelial Yap/Taz are required for functional alveolar regeneration following acute lung injury
Jun 23, 2023
Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen.
Jun 22, 2023
The essential inter-domain interaction between NUDT9H and channel domain of human TRPM2 is also accomplished in trans
Jun 22, 2023
Membrane contact sites regulate vacuolar fission via sphingolipid metabolism
Jun 22, 2023
Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of stem cell and oncogenic programs
Jun 22, 2023
Functional interaction of torsinA and its activators in liver lipid metabolism
Jun 22, 2023
Single cell compendium of the muscle microenvironment in peripheral artery disease reveals capillary endothelial heterogeneity and activation of resident macrophages
Jun 22, 2023
Centriole elimination during C. elegans oogenesis initiates with loss of the central tube protein SAS-1
Jun 22, 2023
Cyclin A/cdk activity and FAM122A-dependent inhibition of PP2A-B55 are essential to trigger mitosis.
Jun 22, 2023
Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1α
Jun 22, 2023
TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells
Jun 22, 2023
An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation
Jun 22, 2023
Exploring the interactome of PML nuclear subdomains during fatty acid stress using APEX2-mediated proximity labeling
Jun 22, 2023
IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A
Jun 22, 2023
Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells
Jun 22, 2023
ER-Mitochondria Contact Sites expand during mitosis
Jun 22, 2023
Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization
Jun 22, 2023
Reorganization of the Flagellum Scaffolding Induces a Sperm Standstill Required for Fertilization
Jun 22, 2023
Thermosensitivity of translation underlies the mammalian nocturnal-diurnal switch
Jun 22, 2023
Structural Basis for Regulated Assembly of the Mitochondrial Fission GTPase Drp1
Jun 22, 2023
Cellular insights of beech leaf disease reveal abnormal ectopic cell division of symptomatic interveinal leaf areas
Jun 22, 2023
A Dual Color Pax7 and Myf5 In Vivo Reporter to Investigate Muscle Stem Cell Heterogeneity in Regeneration and Aging
Jun 21, 2023
Extracellular Matrix Stiffness Promotes Vascular Smooth Muscle Cell Calcification by Reducing The Levels of Nuclear Actin Monomers
Jun 19, 2023
Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment
Jun 19, 2023
Proteomics reveals how the tardigrade damage suppressor protein teaches transfected human cells to survive UV-C stress
Jun 19, 2023
GTPase activating protein DLC1 spatio-temporally regulates Rho signaling
Jun 19, 2023
Mitotic spindle positioning protein (MISP) is an actin bundler that senses ADP-actin and binds near the pointed ends of filaments
May 06, 2023
Rme-6 integrates EGFR trafficking and signalling to regulate ERK1/2 signalosome dynamics
May 05, 2023
Coordination of actin plus-end dynamics by IQGAP1, formin, and capping protein
May 05, 2023
MskAge - An Epigenetic Biomarker of Musculoskeletal Age Derived from a Genetic Algorithm Islands Model
May 05, 2023
Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology
May 05, 2023
Non-local model of chemotaxis based on peer attraction
May 05, 2023
Machine vision reveals micronucleus rupture as a potential driver of the transcriptomic response to aneuploidy
May 05, 2023
Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal dynamics in skin keratinocytes
May 05, 2023
Circulating Microparticles: Optimization and Standardization of Isolation Protocols and Reassessment of Their Characteristics and Functions
May 05, 2023
Effects of TP63 Mutations on Keratinocyte Adhesion and Migration
May 05, 2023
Keratin isoform shifts modulate motility signals during wound healing
May 05, 2023
SUMOylation of MFF is required for stress-induced mitochondrial fission
May 05, 2023
Acute joint inflammation induces a sharp increase in the number of synovial fluid EVs and modifies their phospholipid profile
May 05, 2023
Necrosulfonamide causes ubiquitination of PCM1 and impairs Ciliogenesis and Autophagy
May 05, 2023
Engineering of a biosensor for intracellular aspartate
May 04, 2023
Long-distance Wnt transport in axons highlights cell type-specific modes of Wnt transport in vivo
May 04, 2023
Direct quantification of chemogenetic H2O2 production in live human cells.
May 04, 2023
K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ)
May 04, 2023
Interface-acting nucleotide controls polymerization dynamics at microtubule plus- and minus-ends
May 04, 2023
Mechanical Dissociation of Tissues for Single Cell Analysis Using a Simple Motorized Device
May 04, 2023
A comparative ultrastructure study of the tardigrade Ramazzottius varieornatus in the hydrated state, after desiccation and during the process of rehydration.
May 04, 2023
Generation of a human Tropomyosin 1 knockout iPSC line
May 04, 2023
Uncovering the multi-step process of stable microtubule bundle formation upon entry into quiescence
May 03, 2023
Biomolecular Condensates defined by Receptor Independent Activator of G protein Signaling: Properties and Regulation
May 03, 2023
Cellular Dynamics of Skeletal Muscle Regeneration
May 02, 2023
IL-6 is dispensable for causing cachexia in the colon carcinoma 26 model
May 02, 2023
Modification of the Neck Linker of KIF18A Alters Microtubule Subpopulation Preference
May 02, 2023
Pannexin 1 modulates angiogenic activities of human endothelial colony-forming cells through IGF-1 mechanism and is a marker of senescence
May 02, 2023
Complement C3 reduces apoptosis in human cardiomyocytes
May 02, 2023
Family-wide analysis of integrin structures predicted by AlphaFold2
May 02, 2023
Preservation of ~12-hour ultradian rhythms of gene expression of mRNA and protein metabolism in the absence of canonical circadian clock
May 02, 2023
An expanded palette of ATP sensors for subcellular and multiplexed imaging
May 02, 2023
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis
May 02, 2023
ClearX9™: an efficient alternative to fetal bovine serum for growing animal cells in vitro
May 02, 2023
A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion
May 01, 2023
Regulation of lipolysis by 14-3-3 proteins on human adipocyte lipid droplets.
May 01, 2023
GPCR binding and JNK3 activation by arrestin-3 have different structural requirements
May 01, 2023
Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone localization and sliding force
May 01, 2023
The highly developed symbiotic system between the solar-powered nudibranch Pteraeolidia semperi and Symbiodiniacean algae
Apr 30, 2023
Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall
Apr 29, 2023
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size
Apr 29, 2023
A single-cell atlas of the aging murine ovary
Apr 29, 2023
Actin- and microtubule-based motors contribute to clathrin-independent endocytosis in yeast
Apr 29, 2023
Cardioprotective Activities of Artemisia lactiflora Extract in Rat Cardiomyoblast (H9c2) Under Inflmmatory Sepsis
Apr 29, 2023
1,25-dihydroxyvitamin D3 potentiates the innate immune response of peripheral blood mononuclear cells from Japanese Black cattle
Apr 29, 2023
Multiscale Model for Ion Transport in Cellular Media and Applications in Smooth Muscle Cells
Apr 29, 2023
Rapid Synthesis of Cryo-ET Data for Training Deep Learning Models
Apr 28, 2023
Selective effects of estradiol on human corneal endothelial cells
Apr 28, 2023
Deciphering the Differential Impact of Thrombopoietin/MPL Signaling on Hematopoietic Stem Cell Function in Bone Marrow and Spleen
Apr 28, 2023
Macrophage migration is differentially regulated by distinct ECM components
Apr 28, 2023
Pigment-Dispersing Factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signaling to insulin-producing cells
Apr 28, 2023
ANDA: An open-source tool for automated image analysis of neuronal differentiation
Apr 28, 2023
Receptor endocytosis orchestrates the spatiotemporal bias of β-arrestin signaling
Apr 28, 2023
Fission yeast CK1 promotes DNA double-strand break repair through both homologous recombination and non-homologous end joining
Apr 28, 2023
Flexing fish: cell surface plasticity in response to shape change in the whole organism
Apr 28, 2023
p53 promotes revival stem cells in the regenerating intestine after severe radiation injury
Apr 28, 2023
Dynamics and Plasticity of Immune Cells within Tumor Microenvironment
Apr 28, 2023
GraphComm: A Graph-based Deep Learning Method to Predict Cell-Cell Communication in single-cell RNAseq data
Apr 27, 2023
Quantifying cell viability through organelle ratiometric probing
Apr 27, 2023
MYPT1 is a non-canonical AKAP that tethers PKA to the MLCP signaling node
Apr 27, 2023
Preparation of physiologically active inside-out vesicles from plant inner mitochondrial membranes
Apr 27, 2023
Live-cell super-resolution nanoscopy reveals modulation of cristae dynamics in bioenergetically compromised mitochondria
Apr 27, 2023
PALS1 is a key regulator of the lateral distribution of tight junction proteins in renal epithelial cells.
Apr 27, 2023
Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins
Apr 27, 2023
Inositol hexakisphosphate kinase 1 is essential for cell junction integrity in the mouse seminiferous epithelium
Apr 27, 2023
TorsinA is essential for the timing and localization of neuronal nuclear pore complex biogenesis
Apr 27, 2023
Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly
Apr 27, 2023
Ferroptosis-Protective Membrane Domains in Quiescence
Apr 27, 2023
Transcriptomic Analysis Of The Ocular Posterior Segment Completes A Cell Atlas Of The Human Eye
Apr 27, 2023
A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona
Apr 26, 2023
Discovery of microRNA-derived RNAs and proteins in human cells
Apr 26, 2023
Can Single Cell Respiration be Measured by Scanning Electrochemical Microscopy (SECM)?
Apr 26, 2023
Epithelial lumen development requires differential participation of the vertebrate clathrin light chain isoforms with dominance of CLCa in vivo
Apr 26, 2023
14-3-3 proteins stabilize actin and vimentin filaments to maintain processes in glomerular podocyte
Apr 26, 2023
Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids
Apr 26, 2023
Target-identification and mechanism-of-action studies of indole terpenoid mimics reveal that proper spindle microtubule assembly is essential for Cdh1-mediated proteolysis of CENP-A
Apr 26, 2023
Functional Relations of CSLD2, CSLD3, and CSLD5 Proteins during Cell Wall Synthesis in Arabidopsis
Apr 26, 2023
Arsenic induces two different interaction modes of SUMO with promyelocytic leukemia (PML) proteins.
Apr 26, 2023
Tension sensing by FAK governs nuclear mechanotransduction, endothelial transcriptome and fate
Apr 26, 2023
A familial natural short sleep mutation promotes healthy aging and extends lifespan in Drosophila
Apr 26, 2023
Competition between transcription and loop extrusion modulates promoter and enhancer dynamics
Apr 26, 2023
mRNA Location and Translation Rate Determine Protein Targeting to Dual Destinations
Apr 26, 2023
Fission yeast ortholog of REEP1-4 promotes autophagosomal enclosure of ER-phagy/nucleophagy cargos
Apr 26, 2023
Induced pluripotent stem cell model revealed impaired neurovascular interaction in genetic small vessel disease CADASIL
Apr 26, 2023
Cdk/Cyclin activity helps set mitotic centrosome size by influencing the centrosome growth rate and growth period
Apr 26, 2023
Culture of Saos-2 cells under hypoxic conditions stimulates rapid differentiation to an osteocyte-like stage
Apr 25, 2023
Simultaneous photoactivation and high-speed structural tracking reveal diffusion-dominated motion in the endoplasmic reticulum
Apr 25, 2023
A mechanism that integrates microtubule motors of opposite polarity at the kinetochore corona
Apr 25, 2023
Chromatin condensation delays human mesenchymal stem cells senescence by safeguarding nuclear damages during long-term in vitro expansion
Apr 25, 2023
Alpha Synuclein Modulates Mitochondrial Ca2+ Uptake from ER During Cell Stimulation and Under Stress Conditions
Apr 24, 2023
ESCRT disruption provides evidence against signaling functions for synaptic exosomes
Apr 24, 2023
XIAP-mediated targeting of endolysosomes to stressed mitochondria occurs in a switch-like, global manner and results in autophagy-independent, sub-organelle level mitochondrial degradation
Apr 24, 2023
Resolving exit strategies of mycobacteria by combining high-pressure freezing with 3D-correlative light and electron microscopy
Apr 24, 2023
The cortical microtubules of Toxoplasma contribute to the helicity, but not the speed or persistence of parasite movement
Apr 24, 2023
Mitochondrial genome editing: a possible interplay of atherosclerosis-associated mutation m.15059G greater than A with defective mitophagy
Apr 22, 2023
Tbx5 maintains atrial identity by regulating an atrial enhancer network
Apr 22, 2023
CHAF1A promotes the translesion DNA synthesis pathway in response to DNA replication stress
Apr 22, 2023
A metabolically controlled contact site between lipid droplets and vacuoles
Apr 22, 2023
Renal Cl-/H+ antiporter ClC-5 regulates collagen production and release in Dent Disease models
Apr 22, 2023
Notch regulated long non-coding RNA TUG1 regulates smooth muscle cell differentiation in aortic aneurysm
Apr 21, 2023
Unlocking Trypanosome Biology: A Comprehensive Protein-Tagging Toolkit for Localization and Functional Analysis
Apr 21, 2023
Identification of FAM53C as a suppressive binding protein of a neurodevelopmental disorders-related kinase DYRK1A
Apr 21, 2023
Regulation of apico-basolateral trafficking polarity of homologous Copper-ATPases ATP7A and ATP7B
Apr 21, 2023
The ultrastructural nature of human oocytes' cytoplasmatic abnormalities and the role of cytoskeleton dysfunction
Apr 21, 2023
CRB3 and ARP2/3 regulate cell biomechanical properties to set epithelial monolayers for collective movement
Apr 21, 2023
Nuclear growth and import can be uncoupled
Apr 21, 2023
Decoding human in vitro terminal erythropoiesis originating from umbilical cord blood mononuclear cells and pluripotent stem cells
Apr 21, 2023
Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy
Apr 21, 2023
ER structural remodeling requires TAK1/ATAT1-induced microtubule acetylation
Apr 21, 2023
Arabidopsis thaliana subclass I ACTIN DEPOLYMERIZING FACTORs regulate nuclear organization and gene expression
Apr 21, 2023
LDO proteins and Vac8 form a vacuole-lipid droplet contact site required for lipophagy in response to starvation
Apr 21, 2023
Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury
Apr 21, 2023
Upregulated NF-κB pathway proteins may underlie APOE4 associated astrocyte phenotypes in sporadic Alzheimer's disease
Apr 20, 2023
Uncovering the transcriptomic heterogeneity of pancreatic endothelial cells using integrative and comparative single cell gene expression analysis
Apr 20, 2023
Ena/VASP proteins mediate endothelial cell repulsion from ephrin ligands
Apr 20, 2023
Comparative analysis of two Caenorhabditis elegans kinesins KLP-6 and UNC-104 reveals a common and distinct activation mechanism in kinesin-3
Apr 20, 2023
P2X7-dependent exchange of extracellular microparticles and mitochondria by mouse microglia
Apr 19, 2023
ER-dependent membrane repair of mycobacteria-induced vacuole damage
Apr 19, 2023
Ultrastructure of the nebenkern during spermatogenesis in the praying mantid Hierodula membranacea
Apr 19, 2023
Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2
Apr 19, 2023
Impaired H19 lncRNA expression contributes to the compromised developmental angiogenesis in EVL-deficient mice
Apr 19, 2023
Kinetic investigation reveals an HIV-1 Nef-dependent increase in AP-2 recruitment and productivity at endocytic sites
Apr 19, 2023
Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants
Apr 19, 2023
Ki-67 is necessary during DNA replication for forks protection and genome stability
Apr 19, 2023
Design principles of Cdr2 node patterns in fission yeast cells
Apr 19, 2023
Partitioning to ordered membrane domains regulates the kinetics of secretory traffic
Apr 19, 2023
Mild ER Stress Impedes Regulated Secretion By Governing Key Exocytotic and granulogenic Molecular Switches
Apr 19, 2023
Dextromethorphan inhibits collagen transport in the endoplasmic reticulum eliciting an anti-fibrotic response in ex-vivo and in vitro models of pulmonary fibrosis
Apr 19, 2023
Impaired AMPK activity contributes to the inflammatory phenotype and the reduced phagocytosis capacity of VASP-deficient macrophages
Apr 19, 2023
Novel protein interaction network of human calcitonin receptor-like receptor revealed by label-free quantitative proteomics
Apr 19, 2023
THE OLFACTORY RECEPTOR Olfr78 REGULATES DIFFERENTIATION OF ENTEROCHROMAFFIN CELLS IN THE MOUSE COLON
Apr 19, 2023
Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development
Apr 18, 2023
Aspergillus SUMOylation mutants have normal dynein function but exhibit chromatin bridges
Apr 18, 2023
Proteomic Investigation of Neural Stem Cell to Oligodendrocyte Precursor Cell Differentiation Reveals Phosphorylation-Dependent Dclk1 Processing
Apr 17, 2023
Disulfiram Exerts anti-pulmonary Fibrosis Effect by Activating PGE2 Synthesis
Apr 17, 2023
mRNA Localization and Local Translation of the Microtubule Severing Enzyme, Fidgetin-Like 2, in Polarization, Migration and Outgrowth
Apr 17, 2023
Serum from pregnant donors induces human beta cell proliferation and insulin secretion
Apr 17, 2023
Focal adhesions are controlled by microtubules through local contractility regulation
Apr 17, 2023
The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments
Apr 17, 2023
Phase partitioning initiates Rab protein membrane domain formation and promote vesicle tethering
Apr 17, 2023
CD45 limits Natural Killer cell development from common lymphoid progenitors
Apr 17, 2023
SARS-CoV-2 shifts transcription of host gene to increase Spike acylation and boost infectivity
Apr 17, 2023
Human airway ex vivo models: new tools to study the airway epithelial cell response to SARS-CoV-2 infection
Apr 17, 2023
SEL1L-HRD1 ER-associated degradation is a new ataxia gene
Apr 14, 2023
Proteasome gene expression is controlled by the coordinated functions of multiple transcription factors
Apr 13, 2023
Binucleated human hepatocytes arise through loss of membrane anchorage to the midbody during endomitosis
Apr 13, 2023
Localization and function of multivesicular-bodies that release exosomes in islet cells: dysregulation during type-2 diabetes
Apr 13, 2023
Extracellular thiamine concentration influences thermogenic competency of differentiating neck area-derived human adipocytes
Apr 13, 2023
Amoeboid cells undergo durotaxis with soft end polarized NMIIA
Apr 13, 2023
A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling
Apr 13, 2023
A novel mouse allele of the DNA/RNA helicase senataxin (Setxspcar3) causing meiotic arrest of spermatocytes and male infertility
Apr 13, 2023
Recruitment of PI4KIIIbeta to the Golgi by ABCD3 is dependent on an upstream pathway of a SNARE complex and golgins
Apr 13, 2023
Interspecies generation of functional muscle stem cells
Apr 12, 2023
Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesis
Apr 12, 2023
RAD52 prevents accumulation of Polalpha-dependent replication gaps at perturbed replication forks in human cells
Apr 12, 2023
Comparison of commercially available differentiation media on morphology, function, and virus-host interaction in conditionally reprogrammed human bronchial epithelial cells
Apr 12, 2023
Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint
Apr 12, 2023
COP9 Signalosome Promotes Neointimal Hyperplasia via Deneddylation and CSN5-Mediated Nuclear Export
Apr 12, 2023
Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
Apr 11, 2023
3D environment modulates persistent lamin distribution and the biomechanical signature of the nucleus.
Apr 10, 2023
Caenorhabditis elegans models for striated muscle disorders caused by missense variants of human LMNA
Apr 09, 2023
mps1 and mad mutations reduce Cryptococcus neoformans titan cell viability
Apr 09, 2023
Transcriptional Regulation of the P-bodies Associated Psoriasis Candidate Gene CCHCR1
Apr 08, 2023
Methotrexate-modulated talin-dynamics drives cellular mechanical phenotypes via YAP signalling
Apr 07, 2023
ApoA-I Protects Pancreatic β-cells from Cholesterol-induced Mitochondrial Damage and Restores their Ability to Secrete Insulin
Apr 07, 2023
Photoreceptor disc incisures form as an adaptive mechanism ensuring the completion of disc enclosure
Apr 07, 2023
Allele pairing at Sun1-enriched domains at the nuclear periphery via T1A3 tandem DNA repeats
Apr 07, 2023
Single-cell transcriptome analysis reveals the cellular atlas of human intracranial aneurysm and highlights inflammation features associated with aneurysm rupture
Apr 07, 2023
Determinants of cytoplasmic microtubule reorganization during ciliogenesis in Chlamydomonas reinhardtii
Apr 07, 2023
The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation
Apr 06, 2023
Xrp1 governs the stress response program to spliceosome dysfunction
Apr 06, 2023
CebraEM: A practical workflow to segmentcellular organelles in volume SEM datasetsusing a transferable CNN-based membraneprediction
Apr 06, 2023
Polarized vesicle transport requires AP-1-mediated recruitment of KIF13A and KIF13B at the trans-Golgi network
Apr 06, 2023
Metformin regulates bone marrow stromal cells to accelerate bone healing in diabetic mice
Apr 06, 2023
Dynein-Powered Cell Locomotion Guides Metastasis of Breast Cancer
Apr 06, 2023
RhoB promotes Salmonella survival by regulating autophagy
Apr 06, 2023
Hepatocyte Dedifferentiation Profiling In Alcohol-Related Liver Disease Identifies CXCR4 As A Driver Of Cell Reprogramming
Apr 06, 2023
The recycling endosome biogenesis machinery coordinates BACE1 endosomal sorting and amyloid-Beta production
Apr 06, 2023
Ser14-RPN6 Phosphorylation Mediates the Activation of 26S Proteasomes by cAMP and Protects against Cardiac Proteotoxic Stress in Mice
Apr 06, 2023
The Effect of E-Cigarettes on the Human Heart Studied using Cardiomyocytes Generated from Induced Pluripotent Stem Cells
Apr 06, 2023
Identification of LMAN1 and SURF4 dependent secretory cargoes
Apr 06, 2023
METTL3 is essential for small intestinal epithelial proliferation via regulation of growth factor signaling including KRAS
Apr 06, 2023
Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development
Apr 05, 2023
Quantification of extracellular matrix components in immunolabeled tissue samples
Apr 05, 2023
Self-supervised denoising for structured illumination microscopy enables long-term super-resolution live-cell imaging
Apr 05, 2023
Syndecan-1 and thrombomodulin are early biomarkers for development of endotheliopathy in trauma and hemorrhagic shock
Apr 04, 2023
Coronary Artery Disease Risk Gene PRDM16 is Preferentially Expressed in Vascular Smooth Muscle Cells and a Potential Novel Regulator of Smooth Muscle Homeostasis
Apr 04, 2023
A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells
Apr 04, 2023
Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using In vitro Platform for Improving Insulin Therapy
Apr 04, 2023
IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1beta secretion
Apr 04, 2023
Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition
Apr 04, 2023
Microalgae as a novel biofactory for biocompatible and bioactive extracellular vesicles
Apr 04, 2023
Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes
Apr 04, 2023
ATP13A4 upregulation drives the elevated polyamine transport system in the breast cancer cell line MCF7
Apr 03, 2023
Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
Apr 03, 2023
Ciliary protein CEP290 regulates focal adhesion via microtubule system in non-ciliated cells
Apr 03, 2023
Mitochondrial GTP Metabolism Regulates Reproductive Aging
Apr 03, 2023
The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms
Apr 03, 2023
The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes.
Apr 02, 2023
Anti-nucleolin aptamer, iSN04, inhibits the inflammatory responses in myoblasts by modulating the β-catenin/NF-κB signaling pathway
Apr 02, 2023
Increase in primary cilia number and length upon VDAC1 depletion contributes to attenuated proliferation of cancer cells
Apr 02, 2023
β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor
Apr 02, 2023
A Suite of Mouse Reagents for Studying Amelogenesis
Apr 02, 2023
Selective inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation
Apr 02, 2023
Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants
Apr 02, 2023
Membrane-induced 2D phase separation of focal adhesion proteins
Apr 01, 2023
Stress-induced clustering of the UPR sensor IRE1 is driven by disordered regions within its ER lumenal domain
Apr 01, 2023
An intermembrane space protein facilitates completion of mitochondrial divisionin yeast
Apr 01, 2023
Uip4 governs growth phase-dependent organelle remodeling by modulating Saccharomyces cerevisiae lipidome
Apr 01, 2023
Vimentin cysteine 328 modifications finely tune network organization and influence actin remodeling under oxidative and electrophilic stress
Apr 01, 2023
An Image-Guided Microfluidic System for Single-Cell Lineage Tracking
Apr 01, 2023
Sox11 is enriched in myogenic progenitors but dispensable for development and regeneration of skeletal muscle.
Apr 01, 2023
PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis
Mar 31, 2023
Rhytidome- and cork-type barks of holm oak, cork oak and their hybrids highlight processes leading to cork formation
Mar 31, 2023
Spatiotemporal coordination of Rac1 and Cdc42 at the whole cell level during cell ruffling
Mar 31, 2023
Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR
Mar 31, 2023
Identification and Characterisation of Proteins Binding to a G-Quadruplex Origin G-rich Repeated Element in Mammalian Cells
Mar 31, 2023
Differentiation of vaginal cells from epidermal cells using morphological and autofluorescence properties: Implications for sexual assault casework involving digital penetration
Mar 31, 2023
Frizzled-9 activates YAP to rescue simulated microgravity induced osteoblasts dysfunction.
Mar 31, 2023
CryoET shows cofilactin filaments inside the microtubule lumen
Mar 31, 2023
Regulation of VEGFR2 and AKT signaling by Musashi-2 in lung cancer
Mar 31, 2023
Metabolic reprogramming provides a novel approach to overcome resistance to BH3-mimetics in Malignant Pleural Mesothelioma
Mar 31, 2023
Nucleolar structure connects with global nuclear organization
Mar 31, 2023
Fatty links between multisystem proteinopathy and Small VCP-Interacting Protein
Mar 31, 2023
Nucleoporin Nsp1 surveils the phase state of FG-Nups
Mar 31, 2023
Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism
Mar 31, 2023
Direct single-cell observation of a key E. coli cell cycle oscillator
Mar 31, 2023
The effect of estradiol during the early stages of osteoclast differentiation is associated with the accumulation of phosphorylated p53 in mitochondria and the inhibition of mitochondrial metabolism.
Mar 30, 2023
Mitochondrial H2O2 release does not directly cause genomic DNA damage.
Mar 30, 2023
Mapping RUNX2 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells
Mar 30, 2023
Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis.
Mar 30, 2023
Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer
Mar 30, 2023
Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells
Mar 29, 2023
Morphogen-driven human iPSCs differentiation in 3D in vitro models of gastrulation is precluded by physical confinement.
Mar 29, 2023
Metabolic regulation of misfolded protein import into mitochondria
Mar 29, 2023
Potential of Local Bacillus spp. Isolates as Wilt Disease Biocontrol Agents for Fusarium (Fusarium oxysporum f. sp. cepae) on Wakegi Onions (Allium x wakegi Araki)
Mar 29, 2023
Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models
Mar 29, 2023
The novel roles of bovine milk-derived exosomes on skin anti-aging
Mar 29, 2023
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing
Mar 29, 2023
A new ferrocene derivative blocks KRAS localization and function by oxidative modification at His95.
Mar 29, 2023
Phylobone: a comprehensive database of bone extracellular matrix proteins in human and model organisms
Mar 29, 2023
Ipsilateral restriction of chromosome movement along a centrosome, and apical-basal axis during the cell cycle
Mar 29, 2023
Cerebral Cavernous Malformation severity is impacted by distinct forms of Hyaluronic acid in the vascular microenvironment
Mar 29, 2023
Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology
Mar 29, 2023
Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2
Mar 29, 2023
Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resistance
Mar 29, 2023
Abnormal autophagy is a critical mechanism in TANGO2-related rhabdomyolysis
Mar 29, 2023
Glycosylation differentially affects immune cell-specific tetraspanins CD37 and CD53
Mar 29, 2023
Distinct dystrophin and Wnt/Ror-dependent pathways establish planar-polarized membrane compartments in C. elegans muscles
Mar 28, 2023
Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis
Mar 28, 2023
Ric8 proteins as the neomorphic partners of G alpha o in GNAO1 encephalopathies
Mar 27, 2023
Quantitative proteomics and phosphoproteomics of PPP2R5D variants reveal deregulation of RPS6 phosphorylation through converging signaling cascades
Mar 27, 2023
Cooperative Motility, Force Generation and Mechanosensing in a Foraging Non-Photosynthetic Diatom
Mar 27, 2023
The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores
Mar 27, 2023
Development of Drosophila as a metazoan model to study inorganic polyphosphate biology
Mar 27, 2023
β-actin is essential for structural integrity and physiological function of the retina
Mar 27, 2023
Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
Mar 27, 2023
One-step generation of auxin-inducible degron cells with high-efficiency homozygous tagging
Mar 27, 2023
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons
Mar 27, 2023
Wat1/mLst8, a TOR complex protein regulates mitochondrial integrity and calcium ion homeostasis in fission yeast S. pombe
Mar 27, 2023
Distinct role of TGN-resident clathrin adaptors for Rab5 activation in the TGN-endosome trafficking pathway
Mar 27, 2023
Oxidation-sensitive cysteines drive IL-38 amyloid formation
Mar 26, 2023
Live-cell imaging provides direct evidence for a threshold in CDK activity at the G2/M transition
Mar 26, 2023
Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Mar 26, 2023
Elastomeric Pillar Cages Modulate Actomyosin Contractility of Epithelial Microtissues by Substrate Stiffness and Topography
Mar 25, 2023
Arf1-PI4KIIIβ positive vesicles regulate phosphatidylinositol-3-phosphate signalling to facilitate the fission of lysosomal tubules.
Mar 25, 2023
High-Content Screening to Identify Inhibitors of Dengue Virus Replication
Mar 25, 2023
RB loss sensitizes cells to replication-associated DNA damage by PARP inhibition
Mar 25, 2023
Inducible protein degradation as a strategy to identify Phosphoprotein Phosphatase 6 substrates in RAS-mutant colorectal cancer cells
Mar 25, 2023
Ferroptosis propagates to neighboring cells via cell-cell contacts
Mar 24, 2023
Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy
Mar 24, 2023
TAp73 regulates mitochondrial dynamics and multiciliated cell homeostasis through an OPA1 axis
Mar 24, 2023
Surfactant protein A promotes atherosclerosis through mediating macrophage foam cell formation
Mar 24, 2023
Ex vivo primary liver sections recapitulate disease phenotype and therapeutic rescue for liver monogenic diseases
Mar 24, 2023
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
Mar 24, 2023
Visualization of translation reorganization upon persistent collision stress in mammalian cells
Mar 24, 2023
Proximity mapping of desmosomes reveals a striking shift in their molecular neighbourhood associated with maturation
Mar 24, 2023
Kinetochore dynein is sufficient to biorient chromosomes and remodel the outer kinetochore
Mar 24, 2023
HCC-1 accelerates atherosclerosis by inducing endothelial cells and macrophages pyroptosis and serves as an early diagnostic biomarker
Mar 24, 2023
The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy
Mar 24, 2023
Single-cell mRNA-regulation analysis reveals cell type-specific mechanisms of type 2 diabetes
Mar 24, 2023
De novo serine biosynthesis is protective in mitochondrial disease
Mar 24, 2023
Golgi organization is a determinant of stem cell function in the small intestine
Mar 24, 2023
Single-cell transcriptomics of adult skin VE-cadherin expressing lineages during hair cycle
Mar 24, 2023
Synthetic cell-cycle regulation identifies Mif2CENP-C as a CDK phospho-target at the kinetochore.
Mar 24, 2023
Basement membrane diversification relies on two competitive secretory routes defined by Rab10 and Rab8 and modulated by dystrophin and the exocyst complex
Mar 24, 2023
Mammalian Esophageal Stratified Tissue Homeostasis is Maintained Distinctively by the Epithelial Pluripotent p63+Sox2+ and p63-Sox2+ Cell Populations
Mar 24, 2023
Utilizing flow cytometry sorting signal width to enrich for cells positive to endogenous gene integration of fluorescent proteins
Mar 24, 2023
Retrospective transcriptome analyses identify LINC01013 as an activation marker in human dermal fibroblasts
Mar 23, 2023
Microbially-derived indole-3-acetate alleviates diet induced steatosis and inflammation in mice
Mar 23, 2023
Polar interactions determine head domain-mediated vinculin oligomerization induced by the Shigella IpaA effector
Mar 23, 2023
Evolution of intracellular free radical load in colon adenocarcinoma cells over the course of butyrate-induced redifferentiation
Mar 23, 2023
ODF2 negatively regulates CP110 levels at centrioles/basal bodies to control biogenesis of primary cilia
Mar 22, 2023
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via CASM
Mar 22, 2023
An endocytic myosin essential for plasma membrane invagination powers motility against resistance
Mar 22, 2023
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells
Mar 22, 2023
An integrated RNA-proteomic landscape of drug induced senescence in a cancer cell line
Mar 21, 2023
CHOP drives cells to mutually exclusive cell fates--death and proliferation--during ER stress
Mar 21, 2023
Matters Arising: FBXO38 does not control PD-1 stability
Mar 21, 2023
The combination of CD49b and CD229 reveals a subset of multipotent cells with short-term activity within the hematopoietic stem cell compartment
Mar 21, 2023
A phase-field model for non-small cell lung cancer under the effects of immunotherapy
Mar 21, 2023
Reduction of cortical pulling at mitotic entry facilitates aster centration
Mar 21, 2023
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease
Mar 21, 2023
LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration
Mar 21, 2023
A hierarchical strategy to decipher protein dynamics in vivo with chemical cross-linking mass spectrometry
Mar 21, 2023
AN ARTIFICIAL INTELLIGENCE FOR RAPID IN-LINE LABEL-FREE HUMAN PLURIPOTENT STEM CELL COUNTING AND QUALITY ASSESSMENT
Mar 21, 2023
Expansion microscopy with trypsin digestion and tyramide signal amplification (TT-ExM) for protein and lipid staining
Mar 21, 2023
Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling
Mar 21, 2023
Hexokinase 1 forms rings that constrict mitochondria during energy stress
Mar 21, 2023
Detecting Material State Changes in the Nucleolus by Label-free Digital Holographic Microscopy
Mar 20, 2023
Alamar Blue assay optimization to minimize druginterference and inter-assay viability
Mar 19, 2023
Novel in-silico predicted matrikines are differential mediators of in vitro and in vivo cellular metabolism
Mar 19, 2023
Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy
Mar 19, 2023
Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Mar 19, 2023
Curved adhesions mediate cell attachment to soft matrix fibres in 3D
Mar 19, 2023
ZIP4 is required for normal progression of synapsis and for over 95% of crossovers in wheat meiosis.
Mar 19, 2023
Toxoplasma Membrane Inositol Phospholipid Binding Protein TgREMIND Is Essential for Secretory Organelle Function and Host Infection
Mar 19, 2023
Proximity interaction analysis of the Plasmodium falciparum putative ubiquitin ligase PfRNF1 reveals a role in RNA regulation
Mar 18, 2023
Cyclin E/CDK2 and feedback from soluble histone protein regulate the S phase burst of histone biosynthesis
Mar 18, 2023
Autophagy is Regulated by Mitochondrial Calcium Transporters NCLX and MCU
Mar 18, 2023
The mitophagy receptor Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
Mar 18, 2023
Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery
Mar 18, 2023
Notch1 forms nuclear transcriptional condensates that drive target gene expression.
Mar 18, 2023
Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.
Mar 17, 2023
CRISPR/Cas9-mediated knockout of the ubiquitin variant UbKEKS reveals a role in regulating nucleolar structures and composition.
Mar 17, 2023
A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking
Mar 17, 2023
MFN2-dependent recruitment of ATAT1 coordinates mitochondria motility with alpha-tubulin acetylation and is disrupted in CMT2A
Mar 16, 2023
Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis
Mar 16, 2023
A protein hydroxylase couples epithelial membrane biology to nucleolar ribosome biogenesis
Mar 16, 2023
Cross-species single-cell comparison of systemic and cardiac inflammatory responses after cardiac injury
Mar 16, 2023
MBNL1 regulates programmed postnatal switching between regenerative and differentiated cardiac states.
Mar 16, 2023
CellDeathPred: A Deep Learning framework for Ferroptosis and Apoptosis prediction based on cell painting
Mar 15, 2023
Adrenal extramedullary hematopoiesis as an inducible model of the adult hematopoietic niche
Mar 15, 2023
Keratinocyte dynamics modulate the spatial organization of redox signaling during sensory neuron regeneration
Mar 15, 2023
N-WASP-dependent branched actin polymerization attenuates B-cell receptor signaling by increasing the molecular density of receptor clusters
Mar 15, 2023
A Novel Transcription Factor Combination for Direct Reprogramming to a Spontaneously Contracting Human Cardiomyocyte-like State
Mar 15, 2023
Rab46: a novel player in mast cell function
Mar 14, 2023
A Novel HIF-2α/ARNT Signaling Pathway Protects Against Microvascular Dysfunction and heart failure After Myocardial Infarction
Mar 14, 2023
The fission yeast cytokinetic ring component Fic1 promotes septum formation
Mar 14, 2023
Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control
Mar 14, 2023
Voltage-dependent volume regulation controls epithelial cell extrusion and morphology
Mar 14, 2023
Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)
Mar 14, 2023
Overexpression of IkappaBalpha modulates NF-kappaB activation of inflammatory target gene expression
Mar 14, 2023
HEATR5B associates with dynein-dynactin and selectively promotes motility of AP1-bound endosomal membranes
Mar 14, 2023
Integrin-based adhesions promote cell-cell junction remodelling and cytoskeletal rearrangements to drive embryonic wound healing
Mar 14, 2023
The ion channel Trpc6a regulates the cardiomyocyte regenerative response to mechanical stretch.
Mar 14, 2023
Identification of potential selective autophagy receptors from protein-content profiling of autophagosomes
Mar 14, 2023
LiverZap: A chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration
Mar 14, 2023
Pten is a disconnecting node in the molecular landscape of the proliferation/quiescence decision during mammary gland acinogenesis
Mar 14, 2023
Manipulation of the nucleoscaffold potentiates cellular reprogramming kinetics
Mar 13, 2023
Transcription repression of Cry2 via Per2 interaction promotes adipogenesis
Mar 13, 2023
Differential translation of mRNA isoforms underlies oncogenic activation of cell cycle kinase Aurora A
Mar 13, 2023
Histone methyltransferase SUV39H1 regulates the Golgi complex via the nuclear envelope-spanning LINC complex
Mar 13, 2023
Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle
Mar 12, 2023
Pharmacologic Activation of an Integrated Stress Response Kinase Promotes Mitochondrial Remodeling
Mar 12, 2023
Characterization of extracellular matrix deposited by segmental trabecular meshwork cells
Mar 12, 2023
RAB18 confers protection to lipid droplets from lysolipophagy and counters cellular steatosis
Mar 11, 2023
Centriole Remodeling Evolved into Centriole Degradation in Mouse Sperm
Mar 11, 2023
Hsc70-4 mediates internalization of environmental dsRNA at the surface of Drosophila S2 cells
Mar 11, 2023
Hepatic Lipid Droplet-Associated Proteome Changes Distinguish Dietary-Induced Fatty Liver from Insulin Resistance in Male Mice.
Mar 10, 2023
Identifying Fibrogenic Cells Following Salivary Gland Obstructive Injury
Mar 10, 2023
Circadian clock-gated cell renewal controls time-dependent changes in taste sensitivity
Mar 10, 2023
Single-cell time series analysis reveals the dynamics of in vivo HSPC responses to inflammation
Mar 10, 2023
Ontology for Cellular Senescence Mechanisms
Mar 10, 2023
The Golgi checkpoint: Golgi unlinking during G2 is required for correct spindle formation and cytokinesis
Mar 07, 2023
Exploring the evolution and function of Canoes intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis
Mar 07, 2023
A sample preparation procedure enables acquisition of 2-channel super-resolution 3D STED image of an entire oocyte
Mar 07, 2023
Replisome loading reduces chromatin motion independent of DNA synthesis
Mar 07, 2023
Bsc2 is a novel regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation
Mar 07, 2023
Temporal Coordination of the Transcription Factor Response to H2O2 stress
Mar 07, 2023
Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease.
Mar 07, 2023
A novel role of macrophage PIST protein in regulating Leishmania major infection
Mar 07, 2023
Hyperactive Ras disrupts cell size control and a key step in cell cycle entry in budding yeast
Mar 07, 2023
The FSGS disease gene product and nuclear pore protein NUP205 regulates nuclear localization and activity of the transcriptional regulators YAP and TAZ in podocytes
Mar 07, 2023
Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport causing congenital hypophosphatemia
Mar 07, 2023
Regulation of Traction Force through the Direct Binding of Basigin and Calpain 4
Mar 07, 2023
Single-Cell Map of Dynamic Multicellular Ecosystem of Radiation-Induced Intestinal Injury
Mar 07, 2023
Cryo-electron tomography sheds light on the elastic nature of the Trypanosoma brucei tripartite attachment complex
Mar 07, 2023
Calorie Restriction activates a gastric Notch-FOXO1 pathway to expand Ghrelin cells
Mar 07, 2023
The MYO1B and MYO5B motor proteins and the SNX27 sorting nexin regulate membrane mucin MUC17 trafficking in enterocytes
Mar 07, 2023
Atherosclerosis is a smooth muscle cell-driven tumor-like disease
Mar 07, 2023
Peroxisomal compartmentalization of amino acid biosynthesis reactions imposes an upper limit on compartment size
Mar 07, 2023
Loss of kinase Atg1 increases yeast maintenance energy requirement
Mar 07, 2023
Endothelial cell-derived lactate triggers mesenchymal stem cell histone lactylation to attenuate osteoporosis
Mar 06, 2023
Novel determinants of NOTCH1 trafficking and signaling in breast epithelial cells
Mar 06, 2023
FARL-11 (STRIP1/2) is Required for Sarcomere and Sarcoplasmic Reticulum Organization in C. elegans
Mar 06, 2023
Mitochondrial translation regulates terminal erythroid differentiation by maintaining iron homeostasis
Mar 06, 2023
Chromatin binding by HORMAD proteins regulates meiotic recombination initiation
Mar 05, 2023
MerTK mediates the immunologically silent uptake of alpha-synuclein fibrils by human microglia
Mar 05, 2023
Development of membrane-like pre-stem cells after released from tube-shaped niches
Mar 05, 2023
In vivo reprogramming of wound-resident cells generates skin with hair
Mar 05, 2023
A proximity-dependent biotinylation map of cytosol-facing organelle outer membrane proteome in living Arabidopsis cells
Mar 04, 2023
Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling
Mar 04, 2023
Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3
Mar 04, 2023
Mutagenic-end joining results in smaller deletions in heterochromatin relative to euchromatin
Mar 04, 2023
5-iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFkappaB signaling
Mar 03, 2023
Feeder-Free Generation of Endocardial and Cardiac Valve Cells from Human Pluripotent Stem Cells
Mar 03, 2023
Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation
Mar 03, 2023
Enrichment and delivery of target proteins into the cell cytosol via Outer Membrane Vesicles
Mar 03, 2023
Re-engineering of TNFα-NF-κB signalling dynamics in cancer cells using pathogenic E. coli effectors
Mar 03, 2023
A truncated HIV Tat demonstrates potent and specific latency reversal activity
Mar 03, 2023
RNA scaffolds the Golgi ribbon by forming condensates with GM130
Mar 03, 2023
Large Extracellular Vesicles Induce Stronger Prion Infection in Cell Culture than Small Extracellular Vesicles
Mar 03, 2023
Cardiomyocyte transcriptomic signatures in response to Trypanosoma cruzi infection underpin Chagas cardiomyopathy progression.
Mar 03, 2023
Electron microscopic analysis of the influence of iPSC-derived motor neurons on bioengineered human skeletal muscle tissues
Mar 03, 2023
Medium depth influences O2 availability and metabolism in cultured RPE cells
Mar 02, 2023
Probabilistic inference of epigenetic age acceleration from cellular dynamics
Mar 02, 2023
Esm-1 mediates transcriptional polarization associated with diabetic kidney disease
Mar 02, 2023
Monocarboxylate transporters facilitate succinate uptake into brown adipocytes
Mar 02, 2023
Spatiotemporal cell landscape of human embryonic tooth development
Mar 02, 2023
Chemically Tunable FOXM1-D Sensor Revealed FOXM1 Direct Influence on Cell Cycle
Mar 02, 2023
A conserved pressure-driven mechanism for regulating cytosolic osmolarity
Mar 02, 2023
Regulatory sites in the Mon1-Ccz1 complex control Rab5 to Rab7 transition and endosome maturation
Mar 02, 2023
Actin-microtubule crosstalk imparts stiffness to the contractile ring in fission yeast.
Mar 02, 2023
Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA
Mar 02, 2023
The Estrogen Receptor-Related Orphan Receptors (ERRs) Regulate Autophagy through TFEB
Mar 02, 2023
FK506 binding protein 5 regulates cell quiescence-proliferation decision in zebrafish epithelium
Mar 02, 2023
A special envelope separates extra-chromosomal from chromosomal DNA in the cytoplasm of mammalian cells
Mar 02, 2023
Translation dynamics in human cells visualized at high-resolution reveal cancer drug action
Mar 02, 2023
Hypoxic volatile metabolic markers in the MDA-MB-231 breast cancer cell line
Mar 02, 2023
Cell-autonomous metabolic reprogramming and oxidative stress underlie endothelial dysfunction in acute myocardial infarction
Mar 01, 2023
Fat2 polarizes Lar and Sema5c to coordinate the motility of collectively migrating epithelial cells
Mar 01, 2023
GIPC3 couples to MYO6 and PDZ domain proteins and shapes the hair cell apical region
Mar 01, 2023
Comparative Proteomic Analysis of Paired Human Milk Fat Globules and Membranes and Mouse Milk Fat Globules Identifies Core Cellular Systems Contributing to Mammary Lipid Trafficking and Secretion
Mar 01, 2023
Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors
Mar 01, 2023
Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
Mar 01, 2023
Modulated protein-sterol interactions drive oxysterol-induced impaired CXCR4 signalling
Mar 01, 2023
A novel in-vivo phagocytosis assay to gain cellular insights on sponge-microbe interactions
Mar 01, 2023
The Role of HERG channel in the Secretion of Glucagon-Like Peptide-1 (GLP-1) from Murine Intestinal L-Cells
Mar 01, 2023
Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screen
Mar 01, 2023
Bulk RNA-Sequencing of small airway cell cultures from IPF and post-COVID lung fibrosis patients illustrates disease signatures and differential responses to TGF-β1 treatment
Mar 01, 2023
Heat inactivation of foetal bovine serum causes protein contamination of extracellular vesicles
Mar 01, 2023
Tyrosyl-DNA phosphodiesterase 1 (TDP1) and SPRTN protease repair histone 3 and topoisomerase 1 DNA-protein crosslinks in vivo
Mar 01, 2023
Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins
Mar 01, 2023
A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling
Mar 01, 2023
Local administration of a novel siRNA modality into the CNS extends survival and improves motor function in the SOD1G93A mouse model for ALS
Feb 28, 2023
Mitochondrial translocation of TFEB regulates complex I and inflammation
Feb 28, 2023
Syndapin Regulates the RAP-1 GTPase to Control Endocytic Recycling via RHO-1 and Non-Muscle Myosin II
Feb 28, 2023
SIRT6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes
Feb 28, 2023
FREEDA: an automated computational pipeline guides experimental testing of protein innovation by detecting positive selection
Feb 28, 2023
Function of ERphagy receptors is regulated via phosphorylation-dependent ubiquitination pathways
Feb 28, 2023
A Conserved Requirement for RME-8/DNAJC13 in Neuronal Autolysosome Reformation
Feb 28, 2023
A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution
Feb 28, 2023
CRISPR/Cas9-based edition of frataxin gene in Dictyostelium discoideum for Friedreich's Ataxia disease modeling
Feb 28, 2023
Molecular mechanisms of heavy metal adaptation of an extremophilic red alga Cyanidioschyzon merolae
Feb 27, 2023
Specific subcellular localization drives the different functions of CDC42 isoforms during migration
Feb 27, 2023
Airway secretory cell-derived p63+ progenitors contribute to alveolar regeneration after sterile lung injury
Feb 27, 2023
Mutual regulation of transcriptomes between pneumocytes and fibroblasts mediates alveolar regeneration
Feb 27, 2023
Aurora B spatial separation from its outer kinetochore substrates stabilizes chromosome biorientation when tension is applied
Feb 27, 2023
NuSAP participates in metaphase spindle length control in mammalians
Feb 27, 2023
Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol for better intracellular growth
Feb 27, 2023
Active zone protein SYD-2/Liprin-α acts downstream of LRK-1/LRRK2 to regulate polarized trafficking of synaptic vesicle precursors through clathrin adaptor protein complexes
Feb 26, 2023
Spatial transcriptomic atlas of shoot organogenesis in tomato callus
Feb 26, 2023
Short Tandem Repeat Profiling via Next Generation Sequencing for Cell Line Authentication
Feb 26, 2023
LRRC23 loss-of-function impairs radial spoke 3 head assembly and causes defective sperm motility underlying male infertility
Feb 26, 2023
Confinement with Myosin-II suppression increases heritable loss of chromosomes, using live-cell ChReporters
Feb 26, 2023
Non-muscle myosin 2 filaments are processive in cells
Feb 26, 2023
Control of human pancreatic beta cell kinome by GLP-1R biased agonism
Feb 26, 2023
Recent developments in the production of 2D- and 3D colon and stomach adenocarcinomas primary cell models
Feb 26, 2023
Ulinastatin Ameliorates Cardiac Ischemia/Reperfusion Injury via Inhibiting the tissue kallikrein-kinin system
Feb 26, 2023
The Kinase Module of the Mediator regulates cell cycle re-entry and transcriptional response following DNA damage
Feb 26, 2023
Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway
Feb 26, 2023
Dynamical modeling reveals RNA decay mediates the effect of matrix stiffness on aged muscle stem cell fate
Feb 25, 2023
Multimodal decoding of human liver regeneration
Feb 25, 2023
Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction
Feb 25, 2023
Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells
Feb 25, 2023
The level of Nck rather than N-WASP determines the rate of actin-based motility of Vaccinia
Feb 24, 2023
Optineurin provides a mitophagy contact site for TBK1 activation
Feb 24, 2023
APLNR marks a cardiac progenitor derived with human induced pluripotent stem cells
Feb 23, 2023
Exon 44 skipping in Duchenne muscular dystrophy: NS-089/NCNP-02, a dual-targeting antisense oligonucleotide
Feb 23, 2023
Desmosome-anchored intermediate filaments facilitate tension-sensitive RhoA signaling for epithelial homeostasis
Feb 23, 2023
Angiopoietin-like 4 promotes the proliferation and migration of epidermal stem cells and contributes to the re-epithelialization of cutaneous wounds
Feb 23, 2023
A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases in extracellular matrix abnormalities
Feb 23, 2023
Multiplex Base Editing to Protect from CD33-Directed Therapy: Implications for Immune and Gene Therapy
Feb 23, 2023
The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts
Feb 23, 2023
Luminescence-based screening for extracellular vesicle release modulators reveals a role for PI4KIIIβ in exosome biogenesis upon lysosome inhibition
Feb 23, 2023
MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement
Feb 23, 2023
MicroRNA-195-3p as a potential regulator of hypoxic injury in HUVECs
Feb 23, 2023
Mechanisms of Nuclear Pore Complex disassembly by the mitotic Polo-Like Kinase 1 (PLK-1) in C. elegans embryos
Feb 22, 2023
Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy
Feb 22, 2023
A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells
Feb 22, 2023
Rab12 regulates LRRK2 activity by promoting its localization to lysosomes
Feb 22, 2023
OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
Feb 22, 2023
RelB represses miR-193a-5p expression to promote the phenotypic transformation of vascular smooth muscle cells in aortic aneurysm
Feb 22, 2023
Cellular protection from H2O2 toxicity by Fv-Hsp70 and mutants of Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase.
Feb 22, 2023
Isoform-specific targeting properties of the protocadherin CDHR5 control its apical delivery to promote brush border assembly
Feb 22, 2023
The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery
Feb 22, 2023
Real-time monitoring of cell surface protein arrival with split luciferases
Feb 22, 2023
O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations
Feb 22, 2023
Transition to the structurally vulnerable nuclear state is an integral part of mouse embryonic development
Feb 21, 2023
Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity.
Feb 21, 2023
Lower shear stress exacerbates atherosclerosis by inducing the generation of neutrophil extracellular traps via Piezo1-mediated mechanosensation
Feb 21, 2023
Tau-Tubulin Kinase 2 restrains microtubule-depolymerizer KIF2A to support primary cilia growth.
Feb 21, 2023
Modulation of WNT, Activin/Nodal and MAPK Signaling Pathways Increases Arterial Hemogenic Endothelium and Hematopoietic Stem/Progenitor Cell Formation During Human iPSC Differentiation
Feb 21, 2023
Wnt/β-catenin signaling within multiple cell types dependent upon kramer regulates Drosophila intestinal stem cell proliferation
Feb 21, 2023
Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells
Feb 21, 2023
Microtubule binding of the human HAUS complex is directly controlled by importins and Ran-GTP
Feb 20, 2023
Distinct mobility patterns of BRCA2 molecules at DNA damage sites
Feb 20, 2023
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Feb 20, 2023
Crosstalk between Rac and Rho GTPase activity mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
Feb 20, 2023
Machine learning inference of continuous single-cell state transitions during myoblast differentiation and fusion
Feb 19, 2023
Single-cell transcriptomics analysis reveals extracellular matrix remodelling in carious human dental pulp
Feb 18, 2023
CCDC15 localizes to the centriole inner scaffold and regulates centriole integrity and ciliogenesis
Feb 18, 2023
Genetic Screen Uncovers a Dual Role for Phospholipids in Mitochondrial-Derived Compartment Biogenesis
Feb 18, 2023
Single-cell transcriptome analysis on the anatomic positional heterogeneity of pig skin
Feb 18, 2023
Transcriptional heterogeneity in diabetic foot wounds
Feb 18, 2023
HECTD1 is both a positive regulator and substrate of caspase-3 activity during apoptotic cell death
Feb 18, 2023
A Single Cell Time Course of Senescence Uncovers Discrete Cell Trajectories and Transcriptional Heterogeneity
Feb 18, 2023
Vimentin impacts centrosome function and microtubule acetylation
Feb 18, 2023
Proliferating cell nuclear antigen involves in temperature stress tolerance of Ulva prolifera
Feb 18, 2023
Integrated Cell Landscape and Dynamics in the Progression of Bone Repair
Feb 18, 2023
Crosstalk in skin: Loss of desmoglein 1 in keratinocytes inhibits BRAFV600E-induced cellular senescence in human melanocytes
Feb 17, 2023
Nanojunctions: Specificity of Ca2+ signalling requires nano-scale architecture of intracellular membrane contact sites
Feb 17, 2023
Hsp70/Hsp90 organizing protein (HOP) maintains CRAF kinase activity and regulates MAPK signaling by enhancing Hsp90-CRAF association
Feb 17, 2023
A cleaved METTL3 potentiates the METTL3-WTAP interaction and breast cancer progression
Feb 17, 2023
A cell surface code mediates tissue-intrinsic defense against aberrant cells in epithelia
Feb 17, 2023
Comparative transcriptomics reveal differential gene expression in Plasmodium vivax geographical isolates and implications on erythrocyte invasion mechanisms
Feb 16, 2023
Visualizing H2O2 and NO in endothelial cells: strategies and pitfalls
Feb 16, 2023
Inhibiting Bet1-mediated transport of MMP14 to plasma membrane impaired GBM cell invasion
Feb 16, 2023
Evolution of the ribbon-like organization of the Golgi apparatus in animal cells
Feb 16, 2023
Starvation induces extracellular accumulation of polyphosphate in Dictyostelium discoideum to inhibit macropinocytosis, phagocytosis, and exocytosis
Feb 16, 2023
Scribble, Lgl1, and myosin IIA interact with α/β-catenin to maintain epithelial junction integrity
Feb 15, 2023
Specialized actin nanoscale layers control focal adhesion turnover
Feb 15, 2023
CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
Feb 15, 2023
Distinct roles of α- and β-tubulin C-terminal tails for ciliary function as revealed by a CRISPR/Cas9 mediated gene editing in Chlamydomonas
Feb 15, 2023
Coupled Biomechanical and Ionic Excitability in Developing Neural Cell Networks
Feb 15, 2023
Scanning electron microscopy of human islet cilia
Feb 15, 2023
Assessing the performance of the Cell Painting assay across different imaging systems
Feb 15, 2023
Endocytosis is regulated through the pH-dependent phosphorylation of Rab GTPases by Parkinson's kinase LRRK2
Feb 15, 2023
Nuclear Myosin 1 regulates platelet activation and immune response in mice
Feb 14, 2023
Histone variant H2B.Z acetylation is necessary for maintenance of Toxoplasma gondii biological fitness
Feb 14, 2023
Threshold inclusion size triggers conversion of huntingtin to prion-like state that is reversible in newly born cells
Feb 14, 2023
Probing the ligand binding specificity of FNBP4 WW domains and interaction with FH1 domain of FMN1
Feb 14, 2023
Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
Feb 14, 2023
Inositol pyrophosphate dynamics in yeast reveals control of the PHO starvation program through 1,5-IP8 and the SPX domain of the CDK inhibitor Pho81
Feb 14, 2023
Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy
Feb 14, 2023
Physiological reprogramming in vivo mediated by Sox4 pioneer factor activity
Feb 14, 2023
Metformin impairs trophoblast metabolism and differentiation in dose dependent manner
Feb 14, 2023
Self-organizing actin networks drive sequential endocytic protein recruitment and vesicle release on synthetic lipid bilayers
Feb 14, 2023
Human primary plaque cell cultures to study mechanisms of atherosclerosis
Feb 13, 2023
Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis
Feb 13, 2023
Ubiquitination is a novel post-translational modification of VMP1 in autophagy of human tumor cells
Feb 13, 2023
Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia.
Feb 13, 2023
Butyrate endows extraocular muscle stem cell-like transcriptomic patterns that ameliorate satellite cell depletion and denervation to slow ALS progression
Feb 13, 2023
Aortic regurgitation provokes phenotypic modulation of smooth muscle cells in the normal ascending aorta
Feb 12, 2023
Unique Amphipathic α-helix Drives Membrane Insertion and Enzymatic Activity of ATG3
Feb 12, 2023
Structure, signals, and cellular elements of the mouse gastric mesenchymal niche
Feb 12, 2023
Simulated microgravity during clino-rotation is disturbed by spurious fluid motion
Feb 12, 2023
Light-Responsive MicroRNAs in Human Retinal Tissue are Differentially Regulated by Distinct Wavelengths of Light
Feb 12, 2023
Targeting GDF15 as a potential therapy for low back pain originating from endplate
Feb 12, 2023
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
Feb 12, 2023
CDK5 activity in retinal pigment epithelium contributes to gap junction dynamics during phagocytosis
Feb 11, 2023
Apelin improves angiogenesis and blood flow reperfusion following lower limb ischemia in diabetic mice
Feb 11, 2023
Proteins with anti-apoptotic action in the hemolymph of caterpillars of the Megalopygidae family acts by maintaining the structure of the cellular cytoskeleton
Feb 11, 2023
Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge
Feb 11, 2023
Ormdl3 regulation of specific ceramides is dispensable for β-cell function and glucose homeostasis under obesogenic conditions
Feb 11, 2023
Regulatory principles of human mitochondrial gene expression revealed by kinetic analysis of the RNA life cycle
Feb 10, 2023
Single cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemia
Feb 10, 2023
A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
Feb 10, 2023
Enhanced Branched-Chain Amino Acid Metabolism Improves Age-related Reproductive Function
Feb 10, 2023
A versatile CRISPR-based system for lineage tracing in living plants
Feb 10, 2023
A Single-Cell RNA-Seq Analysis Unravels The Heterogeniety Of Primary Cultured Human Corneal Endothelial Cells
Feb 10, 2023
Exploring the consequences of redirecting an exocytic Rab onto endocytic vesicles.
Feb 10, 2023
Palmitic acid reduces viability and increases production of reactive oxygen species and respiration in rat tendon-derived cells
Feb 10, 2023
Mechanical forces at the kidney filtration barrier govern spatial orientation of podocyte processes on capillaries
Feb 10, 2023
An immune cell lipid atlas reveals the basis of susceptibility to ferroptosis
Feb 10, 2023
Real-time spectral library matching for sample multiplexed quantitative proteomics.
Feb 09, 2023
Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1)
Feb 09, 2023
Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes
Feb 09, 2023
Catalytic antibodies in arrhythmogenic cardiomyopathy patients cleave desmoglein 2 and N-cadherin and impair cardiomyocyte cohesion
Feb 08, 2023
HOPS-dependent lysosomal fusion controls Rab19 availability for ciliogenesis in polarized epithelial cells
Feb 08, 2023
Mechanisms of spinophilin-dependent pancreas dysregulation underlying diabesity
Feb 08, 2023
Dynamic mapping of proteome trafficking within and between living cells by TransitID
Feb 08, 2023
Ferroptosis is determined by chloride ions
Feb 08, 2023
Modification of gene expression after internalization of Growth Hormone into the cell nucleus
Feb 08, 2023
CD38 promotes hematopoietic stem cell dormancy via c-Fos
Feb 08, 2023
Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
Feb 08, 2023
Separation of function mutations in microcephaly protein CPAP/CENPJ, reveal its role in regulating centriole number and length.
Feb 08, 2023
The clock-modulatory activity of Nobiletin suppresses adipogenesis via Wnt signaling
Feb 08, 2023
Taxol acts differently on different tubulin isotypes
Feb 08, 2023
Quantifying yeast microtubules and spindles using the Toolkit for Automated Microtubule Tracking (TAMiT)
Feb 08, 2023
A Non-Canonical IRAK Signaling Pathway Triggered by DNA Damage
Feb 08, 2023
Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins
Feb 08, 2023
Shift in vacuolar to cytosolic regime of infecting Salmonella from a dual proteome perspective
Feb 07, 2023
UPF3A is a ubiquitously expressed NMD factor among mouse tissues
Feb 07, 2023
Transferrin-induced signaling through transferrin receptor and AKT kinase mediates formation of Rab8- and MICAL-L1-positive tubules involved in receptor recycling
Feb 07, 2023
Vaginal bacteria elicit acute inflammatory response in fallopian tube organoids: a model for pelvic inflammatory disease
Feb 07, 2023
SUMOylation of PTEN promotes DNA end resection through directly dephosphorylating 53BP1 in homologous recombination repair
Feb 07, 2023
A complex three-dimensional microfluidic model that mimics the early stage events in the human atherosclerotic artery
Feb 07, 2023
GLI1 facilitates rheumatoid arthritis by collaborative regulation of DNA methyltransferases
Feb 07, 2023
Constitutive protein degradation induces acute cell death via proteolysis products
Feb 06, 2023
Cell growth dilutes YAP/TAZ influencing its subcellular distribution and phenotypic heterogeneity
Feb 06, 2023
Vaccinia virus induces EMT-like transformation and RhoA-mediated mesenchymal migration
Feb 05, 2023
Distinct Aurora B pools at the inner centromere and kinetochore have different contributions to meiotic and mitotic chromosome segregation
Feb 05, 2023
Microplastics analytics: why we should not underestimate the importance of blank controls
Feb 05, 2023
Brainstem Dbh+ Neurons Control Chronic Allergen-Induced Airway Hyperreactivity
Feb 05, 2023
Targeting sterol regulatory element binding proteins (SREBPs) activation lowers intraocular pressure by halting its mechanosensing function in the trabecular meshwork
Feb 05, 2023
The tyrosine phosphatase LAR acts as a receptor of the nidogen-tetanus toxin complex
Feb 04, 2023
FDX1 regulates cellular protein lipoylation through direct binding to LIAS.
Feb 04, 2023
Role of the small protein Mco6 in the mitochondrial sorting and assembly machinery
Feb 04, 2023
A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and is Differentially Regulated during Hypoxia and Aging
Feb 04, 2023
Deformed wings is an Atg8a-interacting protein that negatively regulates autophagy
Feb 04, 2023
The gag-like gene RTL8 antagonizes PEG10-mediated virus like particles in humans
Feb 04, 2023
Cardiac Troponin I Directly Binds and Inhibits Mitochondrial ATP Synthase: a Noncanonical Role in the Post-Ischemic Heart
Feb 04, 2023
Establishment of beta cell heterogeneity via differential CpG methylation at Nnat
Feb 04, 2023
Long lifetime and selective accumulation of the A-type lamins accounts for the tissue specificity of Hutchinson-Gilford progeria syndrome
Feb 04, 2023
The self-renewal procedures of mesenchymal stem cells in the blood
Feb 04, 2023
Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics
Feb 04, 2023
Different roles of dFOXO and HSF in spatio-temporal dynamics of stress-inducible Hsp70 in lgl-yorkie & lgl-Ras driven epithelial tumours in Drosophila
Feb 03, 2023
ATP synthase-associated CHCH domain proteins are critical for mitochondrial function in Toxoplasma gondii
Feb 03, 2023
PerTurboID: A targeted in situ method to measure changes in a local protein environment reveals the impact of kinase deletion on cytoadhesion in malaria causing parasites
Feb 03, 2023
Two-component Turing reaction-diffusion models can explain how mother centrioles break PLK4 symmetry to generate a single daughter
Feb 03, 2023
Calcium transients trigger switch-like discharge of prostaglandin E2 (PGE2) in an ERK-dependent manner
Feb 03, 2023
Lifelong tissue memory relies on spatially organised dedicated progenitors located distally from the injury
Feb 03, 2023
Force transmission and SUN-KASH higher-order assembly in the LINC complex models
Feb 03, 2023
ADO-MEDIATED SYNTHESIS OF TAURINE ALTERS THE CHROMATIN LANDSCAPE OF INGUINAL ADIPOSE TISSUE TO ENHANCE NON-SHIVERING THERMOGENESIS
Feb 03, 2023
Modelling the Erythroblastic Island Niche of Dyserythropoietic Anaemia Type IV patients using Induced Pluripotent Stem Cells
Feb 03, 2023
The organotypic culture of mouse seminiferous tubules as a reliable methodology for the study of meiosis in vitro
Feb 03, 2023
An ULK1/2-PXN mechanotransduction complex suppresses breast cancer cell migration
Feb 03, 2023
Aurora kinase A/AURKA interacts with the mitochondrial ATP synthase to regulate energy metabolism and cell death
Feb 02, 2023
Pancreatic Deletion of Mitogen-inducible Gene 6 Promotes Beta Cell Proliferation Following Destruction
Feb 02, 2023
Epithelial-mesenchymal transition induces cell-cycle-dependent changes of cortical signalling
Feb 02, 2023
Exosomes derived from BMSCs with miR-124-3p inhibitor protects against LPS-induced endometritis through regulation of DUSP6, p-p65 and p-ERK
Feb 02, 2023
Identification of two β-cell subtypes by 7 independent criteria
Feb 01, 2023
A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity
Feb 01, 2023
Human Abdominal Subcutaneous-Derived Active Beige Adipocytes Carrying FTO rs1421085 Obesity-Risk Alleles Exert Lower Thermogenic Capacity
Feb 01, 2023
The junctions connecting the endoplasmic reticulum to the nuclear envelope are constricted and remodelled during the cell cycle
Feb 01, 2023
An alpha-catenin actin-binding domain unfolding mutant designed to lower force-dependent actin-binding promotes epithelial strengthbut interferes with cell-cell coordination
Feb 01, 2023
TTBK2 mutations associated with spinocerebellar ataxia type 11 disrupt peroxisome dynamics and ciliary localization of SHH signaling proteins
Feb 01, 2023
Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
Feb 01, 2023
Generation and expansion of transitional lung organoids from human pluripotent stem cells
Feb 01, 2023
A role for the V0 sector of the V-ATPase in neuroexocytosis: exogenous V0d blocks complexin and SNARE interactions with V0c
Feb 01, 2023
Mesenchymal Stromal Cell secretome is affected by tissue source, donor age and sex.
Feb 01, 2023
Human ovarian ageing is characterized by oxidative damage and mitochondrial dysfunction
Feb 01, 2023
Single cell DNA methylation ageing in mouse blood
Feb 01, 2023
Perforin-2 is a pore-forming effector of endocytic escape in cross- presenting dendritic cells
Feb 01, 2023
Epitenon-derived cells comprise a distinct progenitor population that contributes to both tendon fibrosis and regeneration following acute injury
Feb 01, 2023
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy
Feb 01, 2023
Microtubule competition and cell growth recenter the nucleus after anaphase in fission yeast.
Feb 01, 2023
p16-dependent upregulation of PD-L1 impairs immunosurveillance of senescent cells
Feb 01, 2023
ARHGAP29 is required for keratinocyte proliferation and migration
Feb 01, 2023
Architecture of the cortical actomyosin network driving apical constriction in C. elegans
Feb 01, 2023
Interplay between PLEKHG3-regulated actin dynamics and lysosomal trafficking in cell motility
Feb 01, 2023
Intravital microscopy of satellite cell dynamics and their interaction with myeloid cells during skeletal muscle regeneration
Feb 01, 2023
Imaging interorganelle phospholipid transport by extended synaptotagmins using bioorthogonally tagged lipids
Feb 01, 2023
USP8 inhibition promotes Parkin-independent mitophagy in the Drosophila brain and in human neurons
Jan 31, 2023
Ataxin-2 polyglutamine expansions aberrantly sequester TDP-43, drive ribonucleoprotein condensate transport dysfunction and suppress local translation
Jan 31, 2023
A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
Jan 31, 2023
Homocysteine accelerates hepatocyte autophagy by upregulation of TFEB via DNMT3b-mediated DNA hypomethylation
Jan 31, 2023
Lateral and longitudinal compaction of PRC1 overlap zones drive stabilization of interzonal microtubules
Jan 31, 2023
The Dietary Fermentable Fiber Inulin Alters the Intestinal Microbiome and Improves Chronic Kidney Disease Mineral-Bone Disorder in a Rat Model of CKD
Jan 31, 2023
Extracellular communication between brain cells through functional transfer of Cre mRNA
Jan 31, 2023
Plasmodium ARK2-EB1 axis drives the unconventional spindle dynamics, scaffold formation, and chromosome segregation of sexual transmission stages
Jan 31, 2023
Remote-refocusing light-sheet fluorescence microscopy enables 3D imaging of electromechanical coupling of hiPSC-derived and adult cardiomyocytes in co-culture
Jan 29, 2023
Therapy Development for Microvillus Inclusion Disease using Patient-derived Enteroids
Jan 29, 2023
Myeloperoxidase enhances the migration of human choriocarcinoma JEG-3 cells
Jan 29, 2023
Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases
Jan 29, 2023
Germline TFAM levels regulate mitochondrial DNA copy number and mutant heteroplasmy in C. elegans
Jan 29, 2023
The Autophagy Receptor NBR1 Directs the Clearance of Photodamaged Chloroplasts
Jan 28, 2023
Targeted volume Correlative Light and Electron Microscopy of an environmental marine microorganism
Jan 28, 2023
Extracellular vesicles and co-isolated endogenous retroviruses differently affect dendritic cells
Jan 28, 2023
A defined clathrin-mediated trafficking pathway regulates sFLT1/VEGFR1 secretion from endothelial cells
Jan 28, 2023
Functional Optimization of Light-Activatable Opto-GPCRs: Illuminating the Importance of the Proximal C-terminus in G-protein Specificity
Jan 28, 2023
Redefining hematopoietic progenitors cells and reaffirming lineage commitment by transcriptional atlas
Jan 28, 2023
Quantifying single cell lipid signaling kinetics after photo-stimulation
Jan 28, 2023
Newly born mesenchymal cells disperse through a rapid mechanosensitive migration
Jan 28, 2023
Nhsl1b regulates mesodermal cell migration by controlling protrusion dynamics during zebrafish gastrulation.
Jan 28, 2023
A better brain? Alternative spliced STIM2 in hominoids arises with synapse formation and creates a gain-of-function variant
Jan 27, 2023
Pooled CRISPR screening of high-content cellular phenotypes by ghost cytometry
Jan 27, 2023
Pseudomonas aeruginosa Siderophores Damage Lung Epithelial Cells and Promote Inflammation
Jan 27, 2023
Integrated post-genomic cell wall analysis reveals floating biofilm formation associated with high expression of flocculins in the pathogen Candida krusei.
Jan 27, 2023
The LCLAT1/LYCAT acyltransferase supports EGF-mediated phosphatidylinositol-3,4,5-trisphosphate and Akt signalling
Jan 27, 2023
A flexible loop in the paxillin LIM3 domain mediates direct binding to integrin β3
Jan 27, 2023
The nanoscale organization of reticulon 4 shapes local endoplasmic reticulum structure in situ
Jan 27, 2023
Decoupling of transcript and protein concentrations ensures budding yeast histone homeostasis in different nutrient conditions
Jan 27, 2023
The actin depolymerizing factor StADF2 alters StREM1.3 plasma membrane nanodomains to inhibit the Potato Virus X
Jan 26, 2023
Label-Free Mammalian Cell Tracking Enhanced by Precomputed Velocity Fields
Jan 26, 2023
Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression
Jan 26, 2023
Ensemble Processing and Synthetic Image Generation For Abnormally Shaped Nuclei Segmentation
Jan 26, 2023
New tools to study the interaction between integrins and latent TGFbeta1
Jan 26, 2023
Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2
Jan 25, 2023
Hsf1 and the molecular chaperone Hsp90 support a "rewiring stress response" leading to an adaptive cell size increase in chronic stress
Jan 25, 2023
Identification of a mitochondrial targeting sequence in cathepsin D and its localization in mitochondria
Jan 24, 2023
Crb3 stabilizes activated Ezrin-Radixin-Moesin to organize the apical domain of multiciliated cells
Jan 24, 2023
rRNA intermediates coordinate the multilayered nucleolar phase transition in C. elegans
Jan 24, 2023
Endothelial vacuole membrane enriched aquaporins regulate microvascular lumenization in development and hyperglycemia
Jan 24, 2023
The Sin3B chromatin modifier restricts cell cycle progression to dictate hematopoietic stem cell differentiation
Jan 24, 2023
Robust and fast multicolor Single Molecule Localization Microscopy using spectral separation and demixing
Jan 24, 2023
IRF1 regulates self-renewal and stress-responsiveness to support hematopoietic stem cell maintenance
Jan 24, 2023
Circadian oscillation in primary cilium length by clock genes regulate fibroblast cell migration
Jan 24, 2023
Y-complex nucleoporins independently contribute to nuclear pore assembly and gene regulation in neuronal progenitors
Jan 24, 2023
A conserved, non-canonical insert in mitochondrial fission protein 1 (FIS1) is required for DRP1 and TBC1D15 recruitment and fission
Jan 24, 2023
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma syndrome negatively regulates telomere length
Jan 23, 2023
Global analysis of aging-related protein structural changes uncovers enzyme polymerization-based control of longevity
Jan 23, 2023
Caltubin regulates microtubule stability via Ca2+-dependent mechanisms favouring neurite regrowth
Jan 23, 2023
A planar-polarized MYO6-DOCK7-RAC1 axis promotes tissue fluidification in mammary epithelia
Jan 23, 2023
Identification of Candidate Mitochondrial Inheritance Determinants Using the Mammalian Cell-Free System
Jan 23, 2023
Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency
Jan 23, 2023
Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion
Jan 23, 2023
Hep3D: A 3D single-cell digital atlas of the liver to study spatio-temporal tissue architecture
Jan 22, 2023
BiFCo: Visualising cohesin assembly/disassembly cycle in living cells.
Jan 22, 2023
Aurora B Kinase Dependent Phosphorylation of Keratin 8 is required for Cytokinesis in Mammalian Cells of Epithelial Origin
Jan 22, 2023
Human Cryptochrome1 dampens homologous recombination at nightfall
Jan 22, 2023
Malaria parasite proliferation implicates a resource-dependent counter mechanism
Jan 21, 2023
Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere length maintenance
Jan 21, 2023
Generation of human alveolar epithelial type I cells from pluripotent stem cells
Jan 21, 2023
Characterization of 3D organotypic epithelial tissues reveals tonsil-specific differences in tonic interferon signaling
Jan 21, 2023
Woronin bodies move dynamically and bidirectionally by hitchhiking on early endosomes in Aspergillus nidulans
Jan 21, 2023
Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure
Jan 21, 2023
Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity
Jan 21, 2023
Extracellular matrices of bone marrow stroma regulate cell phenotype and contribute to distinct stromal niches in vivo
Jan 20, 2023
FGF2-induced Redox Signaling: A Mechanism Regulating Pyruvate Dehydrogenase Driven Histone Acetylation and NANOG Upregulation
Jan 20, 2023
Genome-wide CRISPR screen reveals genetic modifiers of Ca2+-mediated cell death
Jan 14, 2023
Active compensation for changes in TDH3 expression mediated by direct regulators of TDH3 in Saccharomyces cerevisiae
Jan 14, 2023
Age-dependent loss of cohesion protection in human oocytes
Jan 14, 2023
The effect of Dnaaf5 gene dosage on primary ciliary dyskinesia phenotypes
Jan 14, 2023
Transplantation-based screen uncovers inducers of muscle progenitor cell engraftment across vertebrate species
Jan 14, 2023
Coupling During Collective Cell Migration is Controlled by a Vinculin Mechanochemical Switch
Jan 14, 2023
The TNF{blacktriangleup}ARE mouse as a model of intestinal fibrosis
Jan 14, 2023
Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover
Jan 14, 2023
Bidirectional multiciliated cell extrusion is controlled by Notch driven basal extrusion and Piezo 1 driven apical extrusion.
Jan 13, 2023
Mathematical model of nuclear speckle morphology
Jan 13, 2023
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton
Jan 13, 2023
VAP-mediated membrane tethering mechanisms implicate ER-PM contact function in pH homeostasis
Jan 13, 2023
DENND2B activates Rab35 at the intercellular bridge regulating cytokinetic abscission and tetraploidy
Jan 13, 2023
TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration
Jan 13, 2023
Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury
Jan 13, 2023
IL-17 activation undermines longevity and stress tolerance by inhibiting a protective transcriptional network
Jan 13, 2023
The junctional mechanosensor AmotL2 regulates YAP promotor accessibility
Jan 13, 2023
Mitotic events depend on regulation of PLK-1 levels by the mitochondrial protein SPD-3
Jan 12, 2023
MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy
Jan 12, 2023
Insulin determines the effects of TGF-beta on HNF4alpha transcription and epithelial-to-mesenchymal transition in hepatocytes
Jan 12, 2023
Senescent cells deposit intracellular contents through adhesion-dependent fragmentation
Jan 12, 2023
Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase
Jan 12, 2023
End Binding protein 1 promotes specific motor-cargo association in the cell body prior to axonal delivery of Dense Core Vesicles
Jan 12, 2023
Chloroquine induces eryptosis in P. falciparum-infected red blood cells and the release of extracellular vesicles with a unique protein profile
Jan 12, 2023
Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation
Jan 12, 2023
Engraftment of wild-type alveolar type II epithelial cells in surfactant protein C deficient mice
Jan 12, 2023
Independent regulation of Z-lines and M-linesduring sarcomere assembly in cardiac myocytesrevealed by the automatic image analysis software sarcApp
Jan 12, 2023
The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction
Jan 12, 2023
Trophoblast organoids with physiological polarity model placental structure and function
Jan 12, 2023
Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
Jan 11, 2023
Simple, low-cost, and well-performing method, the outgrowth technique, for the isolation of epithelial cells from nasal polyps
Jan 11, 2023
CTCF is essential for proper mitotic spindle structure and anaphase segregation
Jan 10, 2023
Polyploid yeast are dependent on elevated levels of Mps1 for successful chromosome segregation
Jan 10, 2023
LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
Jan 10, 2023
Genome wide-analysis of anterior-posterior mRNA localization in Stentor coeruleus reveals a role for the microtubule cytoskeleton
Jan 10, 2023
A mechanism of melanogenesis mediated by E-cadherin downregulation and its involvement in solar lentigines
Jan 10, 2023
N-Cadherin and alpha-catenin regulate formation of functional tunneling nanotubes
Jan 10, 2023
Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier
Jan 10, 2023
eIF2B localisation and its regulation during the integrated stress response is cell type specific
Jan 10, 2023
Phosphatidylinositol-4-phosphate signaling regulates dense granule biogenesis and exocytosis in Toxoplasma gondii
Jan 09, 2023
Loss of PTPMT1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure
Jan 09, 2023
Neutrophil extracellular trap stabilization by platelet factor 4 reduces thrombogenicity and endothelial cell injury
Jan 09, 2023
YAP-dependent autophagy is controlled by AMPK, SIRT1 and flow intensity in kidney epithelial cells.
Jan 09, 2023
Artificial intelligence supports automated characterization of differentiated human pluripotent stem cells
Jan 08, 2023
A hierarchical pathway for assembly of the distal appendages that organize primary cilia
Jan 08, 2023
Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages
Jan 08, 2023
A humanized Caenorhabditis elegans model of Hereditary Spastic Paraplegia-associated variants in kinesin light chain KLC4
Jan 08, 2023
An oviduct glycan increases sperm lifespan by diminishing ubiquinone and production of reactive oxygen species
Jan 08, 2023
Transient septin sumoylation steers a Fir1-Skt5 protein complex between the split septin ring
Jan 08, 2023
UCHL1-dependent control of Hypoxia-Inducible Factor Transcriptional Activity in Liver Disease.
Jan 08, 2023
Persistent confined migration confers permanent nuclear and functional changes in migrating cells.
Jan 07, 2023
Gaudichaudione H inhibits Herpes Simplex Virus-1 replication by regulating cellular nuclear factor-κB in an interferon-γ-independent manner
Jan 07, 2023
High-throughput single molecule tracking identifies drug interactions and cellular mechanisms
Jan 06, 2023
Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in normal and human mitochondrial disease models
Jan 06, 2023
Targeting the deNEDDylating enzyme NEDP1 to ameliorate ALS phenotypes through Stress Granules dissolution
Jan 06, 2023
Myddosome clustering in IL-1 receptor signaling regulates the formation of an NF-kB activating signalosome
Jan 06, 2023
RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1alpha
Jan 06, 2023
A phosphorylation switch regulates RAB6 function during mitosis
Jan 05, 2023
SCAR and the Arp2/3 complex polarise the actomyosin cortex and plasma membrane organization in asymmetrically dividing neuroblasts
Jan 05, 2023
Abnormal expression of Prolyl oligopeptidase (POP) and its catalytic products Ac-SDKP contributes to the ovarian fibrosis change in Polycystic ovary syndrome (PCOS) mice
Jan 04, 2023
The interfascicular matrix of energy storing tendons houses heterogenous cell populations disproportionately affected by ageing
Jan 04, 2023
scRNA-seq analysis of hemocytes of penaeid shrimp under virus infection
Jan 04, 2023
A fluorogenic chemically induced dimerization technology for controlling, imaging and sensing protein proximity
Jan 04, 2023
Detection of tumor-derived extracellular vesicles interactions with immune cells is dependent on EV-labelling methods
Jan 04, 2023
Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses
Jan 04, 2023
Filopodial protrusion driven by density-dependent Ena-TOCA-1 interactions
Jan 04, 2023
SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression
Jan 03, 2023
In Vivo Delivery of Therapeutic Molecules by Transplantation of Genome-Edited Induced Pluripotent Stem Cells
Jan 03, 2023
Metrics of Coral Microfragment Viability
Jan 03, 2023
Epithelioids: Self-sustaining 3D epithelial cultures to study long-term processes
Jan 03, 2023
A dynamic partitioning mechanism polarizes membrane protein distribution
Jan 03, 2023
Evidence for in vitro extensive proliferation of adult hepatocytes and biliary epithelial cells
Jan 03, 2023
gp120 envelope glycoproteins of HIV-1 Group M Subtype A and Subtype B differentially affect gene expression in human vascular endothelial cells
Jan 03, 2023
Molecular architecture of the ciliary tip revealed by cryo-electron tomography
Jan 03, 2023
Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85beta/AP-2-mediated endocytosis
Jan 02, 2023
Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cortex
Jan 02, 2023
Regionalized protein localization domains in the hair cell kinocilium
Jan 02, 2023
Meiotic Cells Escape Prolonged Spindle Checkpoint Activity Through Premature Silencing and Slippage
Jan 02, 2023
Trafficking of nuclear-encoded apicoplast proteins depends on F-actin and Myosin F in Toxoplasma gondii
Jan 02, 2023
Atheroprone shear stress stimulates noxious endothelial extracellular vesicle uptake by MCAM and PECAM-1 cell adhesion molecules
Jan 02, 2023
Alternative Complement Pathway Regulates Thermogenic Fat Function via Adipsin and Adipocyte-derived C3aR1 in a Sex-dependent Fashion
Dec 31, 2022
The ketone body acetoacetate activates human neutrophils through FFA2R
Dec 31, 2022
Rac negative feedback links local PIP3 rate-of-change to dynamic control of neutrophil guidance
Dec 31, 2022
Indoleamine Dioxygenase and Tryptophan Dioxygenase Activities are Regulated through Control of Cell Heme Allocation by Nitric Oxide
Dec 31, 2022
Pioneer transcription factors coordinate active and repressive gene expression states to regulate cell fate
Dec 30, 2022
FAM76B regulates NF-κB-mediated inflammatory pathway by influencing the translocation of hnRNPA2B1
Dec 30, 2022
A ubiquitin-proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis
Dec 30, 2022
Deucravacitinib, a tyrosine kinase 2 pseudokinase inhibitor, protects human beta cells against proinflammatory insults
Dec 29, 2022
Optimization of energy production and central carbon metabolism in a non-respiring eukaryote
Dec 29, 2022
Glucocorticoid and adrenergic receptor distribution across human organs and tissues: a map for stress transduction
Dec 29, 2022
A Phylogenetic Profiling Approach Identifies Novel Ciliogenesis Genes In Drosophila And C. elegans
Dec 29, 2022
A practical extraction and spatial statistical pipeline for large 3D bioimages
Dec 29, 2022
Evidence of kinesin motors involved in stable kinetochore assembly during early meiosis
Dec 29, 2022
Desmosomal cell cohesion and epidermal differentiation are modulated by dolichol phosphate mannosyltransferase 1 (DPM1) through SERPINB5-dependent mechanisms
Dec 29, 2022
The C. elegans Anchor Cell Transcriptome: Ribosome Biogenesis Drives Cell Invasion through Basement Membrane
Dec 29, 2022
pomBseen: An Automated Pipeline for Analysis of Fission Yeast Images
Dec 27, 2022
Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening
Dec 27, 2022
ISG15-modification of the Arp2/3 complex restricts pathogen spread
Dec 27, 2022
Morphology of the Ovaries, Uterine Tubes and Uterus of Pteronotus gymnonotus (Chiroptera: Mormoopidae)
Dec 26, 2022
MYSM1 co-activates ERα action via histone and non-histone deubiquitination to confer antiestrogen resistance in breast cancer
Dec 24, 2022
Cleavage furrow-directed cortical flows bias mechanochemical pathways for PAR polarization in the C. elegans germ lineage
Dec 23, 2022
The lipid transfer proteins Nir2 and Nir3 sustain phosphoinositide signaling and actin dynamics during phagocytosis
Dec 23, 2022
Integrating human iPSC-derived macrophage progenitors into retinal organoids to generate a mature retinal microglial niche
Dec 23, 2022
ROS signaling-induced mitochondrial Sgk1 regulates epithelial cell plasticity
Dec 23, 2022
Germline-specific role for unconventional components of the γ-tubulin complex in Caenorhabditis elegans
Dec 23, 2022
Evidence for intraflagellar transport in butterfly spermatocyte cilia
Dec 23, 2022
Golgi apposition promotes the generation of specialized lysosomes in differentiated keratinocytes
Dec 23, 2022
Generation and characterization of two immortalized dermal fibroblast cell lines from the spiny mouse (Acomys)
Dec 23, 2022
Fibroblasts-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis
Dec 23, 2022
Peripheral blood mononuclear cells exhibit increased mitochondrial respiration after adjuvant chemo- and radiotherapy for early breast cancer
Dec 22, 2022
Diversification of the recombinant anti-kinesin monoclonal antibody H2
Dec 22, 2022
ATG9A facilitates the biogenesis of influenza A virus liquid condensates near the ER by dissociating recycling vesicles from microtubules
Dec 22, 2022
Cdkn2a regulates beige fat maintenance through BECN1-mediated autophagy
Dec 22, 2022
Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators
Dec 22, 2022
Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretome
Dec 22, 2022
GelMap: Intrinsic calibration and deformation mapping for expansion microscopy
Dec 22, 2022
Cdc14 spatiotemporally regulates Rim4-mRNA complex assembly and stability during meiosis
Dec 22, 2022
FAZ assembly in bloodstream form Trypanosoma brucei requires kinesin KIN-E
Dec 22, 2022
Air-Liquid-Interface Reorganizes Membrane Lipid and Enhance Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colon
Dec 22, 2022
Conserved NIMA kinases regulate multiple steps of endocytic trafficking
Dec 22, 2022
Autophagy inspects Rim4-mRNA interaction to safeguard programmed meiotic translation
Dec 22, 2022
Migration and division in cell monolayers on substrates with topological defect
Dec 22, 2022
Spatial modeling of telomere intra-nuclear distribution reveals non-random organization that varies during cell cycle and depends on LAP2 and BAF
Dec 22, 2022
Anillin forms linear structures and facilitates furrow ingression after septin and formin depletion
Dec 22, 2022
Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
Dec 21, 2022
The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo
Dec 21, 2022
Relation between pH alterations in cellular models of amyotrophic lateral sclerosis and TDP-43 protein aggregation
Dec 21, 2022
Molecular anatomy of eosinophil activation by IL5 and IL33
Dec 21, 2022
CHC22 clathrin membrane recruitment uses SNX5 in bipartite interaction with secretory tether p115
Dec 21, 2022
Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures
Dec 20, 2022
Age-dependent structural reorganization of utricular ribbon synapses
Dec 20, 2022
Single nucleus and spatial transcriptomic profiling of human healthy hamstring tendon
Dec 20, 2022
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis
Dec 20, 2022
Constriction forces imposed by basement membranes regulate developmental cell migration
Dec 20, 2022
Effect of flavonoids hydroxygenkwanin on vascular smooth muscle cell proliferation, migration, and neointimal formation
Dec 20, 2022
Centromere Pairing in Prophase Allows Partner Chromosomes to Orient on the Meiosis I Spindle
Dec 20, 2022
A system for inducible mitochondria-specific protein degradation in vivo
Dec 20, 2022
Perinuclear force regulates SUN2 dynamics and distribution on the nuclear envelope for proper nuclear mechanotransduction
Dec 19, 2022
Spatio-temporal analysis of LC3 association to Mycobacterium tuberculosis phagosomes in human macrophages
Dec 19, 2022
Focal adhesion assembly requires phosphorylation signaling
Dec 19, 2022
Calcium flux through ER-TGN contact sites facilitates cargo export
Dec 19, 2022
Control of stereocilia length during development of hair bundles
Dec 19, 2022
The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress
Dec 19, 2022
LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia via Transcription Factor E3 Inhibition
Dec 18, 2022
The microRNomes of Chinese Hamster Ovary (CHO) cells and their extracellular vesicles, and how they respond to osmotic and ammonia stress
Dec 18, 2022
WRNIP1 PREVENTS G4/R-LOOP-ASSOCIATED GENOMIC INSTABILITY
Dec 18, 2022
UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation independently of the p97 ATPase
Dec 18, 2022
Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis
Dec 18, 2022
The phosphoinositide signature guides the final step of plant cytokinesis
Dec 18, 2022
A high-throughput COPD bronchosphere model for disease-relevant phenotypic compound screening
Dec 18, 2022
PXN/Paxillin Phase Separation Promotes Focal Adhesion Assembly and Integrin Signaling
Dec 18, 2022
Cell migration CRISPRi screens in human neutrophils reveal regulators of context-dependent migration and differentiation state
Dec 16, 2022
Wetting of junctional condensates along the apical interface promotes tight junction belt formation
Dec 16, 2022
Extracellular vesicle cargo metabolome changes in response to the mesenchymal stromal cell microenvironment and influences cell quiescence and activation in a human breast cancer cell model
Dec 16, 2022
mRNA-mediated induced regeneration of the corneal endothelium
Dec 16, 2022
Restoring glucose homeostasis with stomach-derived human insulin-secreting organoids
Dec 16, 2022
TBC1D15 potentiates lysosomal regeneration from damaged membranes
Dec 15, 2022
Discovery And Characterization of Small Molecule Inhibitors of Zika Virus Replication
Dec 15, 2022
Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair
Dec 15, 2022
Experimental study of modified human tendon stem cells to promote graft ligamentation and tendon-bone healing after anterior cruciate ligament reconstruction
Dec 15, 2022
COVID-19 Associated Pulmonary Aspergillosis isolates are genomically diverse but similar to each other in their responses to infection-relevant stresses
Dec 15, 2022
The Kelch13 compartment is a hub of highly divergent vesicle trafficking proteins in malaria parasites
Dec 15, 2022
Tunneling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria
Dec 14, 2022
Merlin-deficient iPSCs show altered pluripotency and constitute a potential in vitro model for NF2-related schwannomas
Dec 14, 2022
Inhibition of early-acting autophagy genes in C. elegans neurons improves protein homeostasis, promotes exopher production, and extends lifespan via the ATG-16.2 WD40 domain
Dec 14, 2022
Mechanistic dissection of alga recognition and uptake in coral-algal endosymbiosis
Dec 14, 2022
An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity
Dec 14, 2022
Facioscapulohumeral muscular dystrophy is associated with altered myoblast proteome dynamics
Dec 14, 2022
Shift of the insoluble content of the proteome in aging mouse brain
Dec 14, 2022
Combined administration of novobiocin and apomorphine mitigates cholera toxin mediated cellular toxicity
Dec 14, 2022
Human Airway Mucociliary Tissue Cultures Chronically Exposed to E-Cigarette Vapors Exhibit Altered Cell Populations and Increased Secretion of Immunomodulatory Cytokines
Dec 14, 2022
Label-free digital holotomography reveals ibuprofen-induced morphological changes to red blood cells
Dec 14, 2022
Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells
Dec 14, 2022
A conserved Plasmodium protein that localizes to liver stage nuclei is critical for late liver stage development.
Dec 14, 2022
A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy
Dec 14, 2022
FOX transcription factors are common regulators of Wnt/β-catenin signaling
Dec 14, 2022
An in silico FSHD muscle fibre for modelling DUX4 dynamics and predicting the impact of therapy
Dec 12, 2022
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation
Dec 12, 2022
Subcellular location defines GPCR signal transduction
Dec 12, 2022
Exploring the interaction between immune cells in testicular microenvironment of azoospermia combining RNA-seq and scRNA-seq
Dec 12, 2022
Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via inositol 1,4,5-trisphosphate receptors
Dec 11, 2022
Mesenchymal Progenitors set the homeostatic inflammatory milieu via the TAK1-NFkB axis.
Dec 11, 2022
Comprehensive Evaluation of the Specificity of Rapamycin as an mTOR Inhibitor
Dec 11, 2022
Transgenic porcine model reveals two roles for LGR5 during lung development and homeostasis
Dec 11, 2022
Sketch the Organoids from Birth to Death Development of an Intelligent OrgaTracker System for Multi-Dimensional Organoid Analysis and Recreation
Dec 11, 2022
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Dec 11, 2022
Structural basis for BIRC6 to balance apoptosis and autophagy
Dec 11, 2022
Primary Cilia are WNT Transducing Organelles whose Biogenesis is Regulated by a WNTPP1 axis
Dec 10, 2022
Wnt-associated adult stem cell marker Lgr6 is required for osteogenesis and fracture healing
Dec 10, 2022
A Host-Harbored Metabolic Susceptibility of Coronavirus Enables Broad-Spectrum Targeting
Dec 10, 2022
Context-dependent functions of mitochondria protein quality control in lung
Dec 10, 2022
FiNuTyper: an automated deep learning-based platform for simultaneous fiber and nucleus type analysis in human skeletal muscle
Dec 10, 2022
Lipid Biosynthesis Perturbation Impairs Endoplasmic Reticulum-Associated Degradation
Dec 10, 2022
Micronutrient Optimization Using Design of Experiments Approach in Tissue Engineered Articular Cartilage for Production of Type II Collagen
Dec 10, 2022
Species-specific LUBAC-mediated M1 ubiquitination counteracts necroptosis by segregating the cellular distribution and fate of activated MLKL
Dec 10, 2022
DNA damage-induced lncRNA MEG9 impacts angiogenesis
Dec 10, 2022
Mre11 liberates cGAS from nucleosome sequestration during tumorigenesis
Dec 10, 2022
Multi-omics analysis of paracetamol exposure identifies dysregulated genes involved in neurotoxicity and neuronal differentiation of human embryonic stem cells
Dec 10, 2022
Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy
Dec 10, 2022
Disrupted RNA editing in beta cells mimics early stage type 1 diabetes
Dec 10, 2022
Competition between chemoattractants causes unexpected complexity and can explain negative chemotaxis
Dec 10, 2022
Genetically encoded multimeric tags for intracellular protein localisation in cryo-EM
Dec 10, 2022
Using light for energy: examining the evolution of phototrophic metabolism via synthetic construction
Dec 08, 2022
Optimisation of immunocytochemistry methodology for the detection of endogenous eIF2B localised foci
Dec 08, 2022
A novel fluorescently-labeled long-chain fatty acid analog for the study of fatty acid metabolism in cultured cells
Dec 08, 2022
SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
Dec 07, 2022
Quantitative mapping of autophagic cargo during nutrient stress reveals YIPF3-YIPF4 as membrane receptors for Golgiphagy
Dec 07, 2022
Non-Canonical Functions of a Mutant TSC2 Protein in Mitotic Division
Dec 07, 2022
The E2 SUMO-conjugating enzyme UBE2I coordinates the oocyte and zygotic transcriptional programs
Dec 06, 2022
Pulse-chase experiments reveal dynamics of RNA binding protein Exuperantia in Drosophila melanogaster egg chambers
Dec 06, 2022
Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating Wnt signaling
Dec 06, 2022
The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions
Dec 05, 2022
Tethering by Uso1 is dispensable: The Uso1 monomeric globular head domain interacts with SNAREs to maintain viability.
Dec 05, 2022
GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program
Dec 05, 2022
Hexokinase 2 localizes to the nucleus in response to glucose limitation but does not regulate gene expression
Dec 05, 2022
Endometrial adhesion G protein-coupled receptors are dynamically expressed across the menstrual cycle and expression is altered by ovarian stimulation
Dec 05, 2022
Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome
Dec 05, 2022
Characterization of adult human skeletal cells in different tissues reveals a CD90+CD34+ periosteal stem cell population
Dec 05, 2022
Rsp5/NEDD4 and ESCRT regulate TDP-43 toxicity and turnover via an endolysosomal clearance mechanism
Dec 05, 2022
Transcriptional activity mediated by beta-CATENIN and TCF/LEF family members is completely dispensable for survival of multiple human colorectal cancer cell lines
Dec 05, 2022
X-Chromosome Target Specificity Diverged Between Dosage Compensation Mechanisms of Two Closely Related Caenorhabditis Species
Dec 05, 2022
Coordinated Regulation of Cdc42ep1, Actin, and Septin Filaments during Neural Crest Cell Migration
Dec 04, 2022
Salmonella actively modulates TFEB in murine macrophages in a growth-phase and time-dependent manner
Dec 04, 2022
Nanoscaled discovery of a shunt rifamycin from Salinispora arenicola using a three-colour GFP-tagged Staphylococcus aureus macrophage infection assay.
Dec 04, 2022
CLASPs stabilize the intermediate state between microtubule growth and catastrophe
Dec 04, 2022
Immortalized bovine satellite cells for cultured meat applications
Dec 03, 2022
Modulating the epigenetic state promotes the reprogramming of transformed cells to pluripotency in a line-specific manner
Dec 02, 2022
Running Kinesin-1 shapes the microtubule acetylation gradient
Dec 02, 2022
Effect of acute ultraviolet radiation on Galleria mellonella health and immunity
Dec 02, 2022
High-sensitivity calcium biosensor on the mitochondrial surface reveals that IP3R channels participate in the reticular Ca2+ leak towards mitochondria
Dec 02, 2022
Histone H1.0 Couples Cellular Mechanical Behaviors to Chromatin Structure
Dec 01, 2022
Establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology
Dec 01, 2022
Perturbation of the mitochondrial import machinery by disease prone Tau affects organelle morphology and reduces neuronal complexity
Dec 01, 2022
The lncRNA landscape of cardiac resident macrophages and identification of Schlafenlnc as a regulator of macrophage migratory function
Dec 01, 2022
Mapping localization of 21 endogenous proteins in the Golgi apparatus of rodent neurons
Dec 01, 2022
Toward a Cell Culture Model of Portal Axis Lipid Handling
Dec 01, 2022
Actin contraction controls nuclear blebbing and rupture independent of actin confinement
Dec 01, 2022
Porcine and human aortic valve endothelial and interstitial cell isolation and characterization
Dec 01, 2022
Modeling cell size control using differential scaling of cell-cycle regulators with cell size
Dec 01, 2022
A selectivity filter in the EMC limits protein mislocalization to the ER
Dec 01, 2022
Mammalian glial protrusion transcriptomes predict localization of Drosophila glial transcripts required for synaptic plasticity
Dec 01, 2022
Intercellular Mitochondrial Transfer as a Rescue Mechanism in Response to Protein Import Failure
Dec 01, 2022
Centrosome formation in the bovine early embryo.
Dec 01, 2022
ZNF524 directly interacts with telomeric DNA and supports telomere integrity
Dec 01, 2022
The secretome of irradiated peripheral mononuclear cells attenuates hypertrophic skin scarring
Dec 01, 2022
PI 3-kinase isoform p110alpha controls smooth muscle cell functionality and protects against aortic aneurysm formation
Dec 01, 2022
Competition between myosin II and βH-Spectrin regulates cytoskeletal tension
Dec 01, 2022
Changes of platelet morphology, ultrastructure and function in patients with acute ischemic stroke based on super-resolution microscopy.
Nov 30, 2022
Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression
Nov 30, 2022
Temporal landscape of mitochondrial proteostasis governed by the UPRmt
Nov 30, 2022
SARS-CoV-2 Envelope-mediated Golgi pH dysregulation interferes with ERAAP retention in cells
Nov 30, 2022
Oxygen is a critical regulator of cellular metabolism and function in cell culture
Nov 29, 2022
Aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk
Nov 29, 2022
The human sperm head spins with a conserved direction during swimming in 3D
Nov 29, 2022
Utilization of an Artery-on-a-chip to unravel novel regulators and therapeutic targets in vascular diseases
Nov 29, 2022
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway
Nov 29, 2022
Human Gasdermin D and MLKL disrupt mitochondria, endocytic traffic and TORC1 signaling in budding yeast
Nov 29, 2022
Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC- βH5 beta cells
Nov 29, 2022
Eosinophilic esophagitis-associated epithelial remodeling may limit esophageal carcinogenesis
Nov 29, 2022
Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2
Nov 29, 2022
Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
Nov 28, 2022
A lysosomal lipid transport pathway that enables cell survival under cholinelimitation
Nov 28, 2022
PTPN1 deficiency modulates BMPR2 signaling and induces endothelial dysfunction in Pulmonary Arterial Hypertension
Nov 28, 2022
The direct interaction with transcriptional factor TEAD4 implied a straightforward regulation mechanism of tumor suppressor NF2
Nov 28, 2022
Identifying transcriptomic downstream targets of genes commonly mutated in Hereditary Hemorrhagic Telangiectasia
Nov 26, 2022
The endocytic recycling pathway is controlled by the ADP-ribosylated GTPase Rab14
Nov 26, 2022
Kinetochore-fiber lengths are maintained locally but coordinated globally by poles in the mammalian spindle
Nov 26, 2022
Metabolic consequences of polyphosphate synthesis and imminent phosphate limitation
Nov 25, 2022
Hepatic WDR23 proteostasis mediates insulin clearance by regulating insulin degrading enzyme activity
Nov 25, 2022
Reverse genetics identifies proteins regulating lipid droplet biogenesis via amphipathic helices
Nov 25, 2022
Fast actin disassembly and fimbrin mechanosensitivity support rapid turnover during clathrin-mediated endocytosis
Nov 25, 2022
A hydrogel-based model of aortic stiffness reveals that microtubules are novel regulators of smooth muscle cell hypertrophy
Nov 25, 2022
GSK3 inhibition reverts mesenchymal transition in human primary corneal endothelial cells
Nov 25, 2022
A non-invasive, fast on/off 'Odourgenetic' Method to Manipulate Physiology
Nov 25, 2022
Cryo-EM Structure of the 50S-HflX Complex Reveals a Novel Mechanism of Antibiotic Resistance in E. coli
Nov 25, 2022
Mouse HP1γ regulates TRF1 expression and telomere stability
Nov 24, 2022
Promoting translational readthrough to augment fibrillin-1 (FBN1) deposition in Marfan syndrome fibroblasts: A proof-of-concept study.
Nov 24, 2022
Prostaglandin E2 prevents radiotherapy-induced alopecia by attenuating transit amplifying cell apoptosis through promoting G1 arrest
Nov 24, 2022
Direct observation of the evolution of cell-type specific microRNA expression signatures supports the hematopoietic origin model of endothelial cells
Nov 24, 2022
Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10
Nov 24, 2022
iLID-antiGFP-nanobody is a flexible targeting strategy for recruitment to GFP-tagged proteins
Nov 24, 2022
Impairment of lipid homoeostasis causes accumulation of protein aggregates in the lysosome
Nov 24, 2022
METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
Nov 24, 2022
Autolysosomal exocytosis of lipids protect neurons from ferroptosis
Nov 24, 2022
Inhibition of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosis
Nov 24, 2022
Platelet pannexin-1 channels modulate inflammation during abdominal aortic aneurysm formation
Nov 24, 2022
Pattern formation and travelling waves in a multiphase moving boundary model of tumour growth
Nov 24, 2022
The intracellular amastigote of Trypanosoma cruzi maintains an actively beating flagellum
Nov 24, 2022
Plasmodium exoerythrocytic parasites redirect trafficking of human proteins to the parasitophorous vacuole
Nov 23, 2022
Golgi-IP, a novel tool for multimodal analysis of Golgi molecular content
Nov 23, 2022
Enhancing Mitochondrial Functions by Optogenetic Clustering
Nov 23, 2022
Designed sensors reveal normal and oncogenic Ras signaling in endomembranes and condensates
Nov 23, 2022
Homophilic interaction of E-Cadherin prevents cell-cell fusion between developing germline and surrounding epithelia in Drosophila ovary
Nov 23, 2022
Identifying Biomarkers of Retinal Pigment Epithelial Cell Stem Cell-derived RPE Cell Heterogeneity and Transplantation Efficacy
Nov 23, 2022
MAP4K4 regulates biomechanical forces at adherens junctions and focal adhesions to promote collective cell migration
Nov 23, 2022
Precision super-resolution cryo-correlative light and electron microscopy for rapid in situ structural analyses of optogenetically-positioned organelles
Nov 23, 2022
A novel crosstalk between Nrf2 and Smad2/3 bridged by two nuanced Keap1 isoforms
Nov 23, 2022
Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 Spike protein
Nov 23, 2022
The WAVE complex drives the morphogenesis of the photoreceptor outer segment cilium
Nov 22, 2022
The Lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope accessibility
Nov 22, 2022
Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis
Nov 22, 2022
An SNF2 helicase-like protein links mitotic transcription termination to sister chromatid resolution
Nov 22, 2022
Notch engagement by Jag1 nanoscale clusters indicates a force-independent mode of activation
Nov 22, 2022
Self-assembly of CIP4 drives actin-mediated asymmetric pit-closing in clathrin-mediated endocytosis
Nov 22, 2022
Mitochondrial defects leading to arrested spermatogenesis and ferroptosis in a mouse model of Leigh Syndrome
Nov 22, 2022
Structural analysis of Toxoplasma gondii sortilin
Nov 21, 2022
Tetraspanner-based nanodomains modulate BAR domain-induced membrane curvature
Nov 21, 2022
The yeast endocytic early/sorting compartment exists as an independent sub-compartment within the trans-Golgi network
Nov 21, 2022
Targeted disruption of transcription bodies causes widespread activation of transcription
Nov 21, 2022
Human endometrial KISS1R inhibits stromal cell decidualization in a manner associated with a reduction in ESR1 levels
Nov 20, 2022
Systematic Approach Identifies Multiple Transcription Factor Perturbations That Rejuvenate Replicatively Aged Human Skin Fibroblasts
Nov 20, 2022
Multi-site assessment of reproducibility in high-content live cell imaging data
Nov 20, 2022
Distinct states of nucleolar stress induced by anti-cancer drugs
Nov 19, 2022
Bridging the light-electron resolution gap with correlative cryo-SRRF and dual-axis cryo-STEM tomography
Nov 19, 2022
Human Early Syncytiotrophoblasts Are Highly Susceptible to SARS-CoV-2 Infection
Nov 18, 2022
Coalescent RNA-localizing and transcriptional activities of SAM68 modulate adhesion and subendothelial basement membrane assembly
Nov 18, 2022
Phase transition of tensin-1 during the focal adhesion disassembly and cell division
Nov 17, 2022
A meiotic midbody structure in mouse oocytes acts as a barrier for nascent translation to ensure developmental competence
Nov 17, 2022
Initiation of fibronectin fibrillogenesis is an enzyme-dependent process
Nov 17, 2022
A stable reference human transcriptome and proteome as a standard for reproducible omics experiments
Nov 17, 2022
Wsc1 acts as a piezosensor in Saccharomyces cerevisiae, enhancing glycerol efflux via aquaglyceroporin Fps1 in response to high hydrostatic pressure
Nov 17, 2022
Novel therapeutic strategies for injured endometrium: Autologous intrauterine transplantation of menstrual blood-derived cells from infertile patients
Nov 17, 2022
Cas9-mediated tagging of endogenous loci using HITAG
Nov 17, 2022
The Centralspindlin proteins Pavarotti and Tumbleweed work with WASH to regulate Nuclear Envelope budding
Nov 17, 2022
Traction force reconstruction assessment on real three-dimensional matrices and cellular morphologies
Nov 17, 2022
Direct conversion of human fibroblasts to pancreatic epithelial cells through transient progenitor states is controlled by temporal activation of defined factors
Nov 17, 2022
IκBα controls dormancy induction in Hematopoietic stem cell development via retinoic acid
Nov 17, 2022
The fission yeast cell size control system integrates pathways measuring cell surface area, volume, and time
Nov 17, 2022
Adaptation to ex vivo culture drives human haematopoietic stem cell loss of repopulation capacity in a cell cycle independent manner
Nov 17, 2022
The critical role of BTRC in hepatic steatosis as an ATGL E3 ligase
Nov 16, 2022
SLC3A2 N-glycosylation and alternate evolutionary trajectories for amino acid metabolism
Nov 16, 2022
Viral Airway Injury Promotes Cell Engraftment in an In Vitro Model of Cystic Fibrosis Cell Therapy
Nov 15, 2022
ESYT1 tethers the endoplasmic reticulum to mitochondria and is required for mitochondrial lipid and calcium homeostasis
Nov 15, 2022
Single-molecule analysis of receptor-beta-arrestin interactions in living cells
Nov 15, 2022
The adenomatous polyposis coli protein 3o years on
Nov 15, 2022
Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation
Nov 15, 2022
The GxcM-Fbp17/RacC-WASP signaling cascade regulates polarized cortex assembly in migrating cells
Nov 15, 2022
Transcription regulates bleb formation and stability independent of nuclear rigidity
Nov 15, 2022
Fisetin Attenuates Cellular Senescence Accumulation During Culture Expansion of Human Adipose-Derived Stem Cells
Nov 15, 2022
Never let me down: Optimizing performance of serum free culture medium for bovine satellite cells
Nov 15, 2022
Nanoscopy of organelles and tissues with iterative ultrastructure expansion microscopy (iU-ExM)
Nov 15, 2022
Systematic identification and characterization of novel genes in the regulation and biogenesis of photosynthetic machinery
Nov 15, 2022
A Junction-Dependent Mechanism Drives Mammary Cell Intercalation for Ductal Elongation
Nov 13, 2022
IL-11 disrupts alveolar epithelial progenitor function
Nov 12, 2022
The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus
Nov 12, 2022
FAP106 is an interaction hub required for stable assembly of conserved and lineage-specific proteins at the cilium inner junction
Nov 12, 2022
A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex restrains excessive mitophagy to prevent mitochondrial disease
Nov 12, 2022
Male mammalian meiosis and spermiogenesis is critically dependent on the shared functions of the katanins KATNA1 and KATNAL1
Nov 12, 2022
Calaxin stabilizes the docking of outer arm dyneins onto ciliary doublet microtubule in vertebrates
Nov 12, 2022
Parallel Activation of Src and Hif1α Increases Localized Glycolytic ATP Generation for Re-assembly of Endothelial Adherens Junctions
Nov 12, 2022
Terminal differentiation of enterocytes is governed by distinct members of Tgfβ superfamily
Nov 12, 2022
A hole in Turing's theory: pattern formation on the sphere with a hole
Nov 11, 2022
A potential function for the helicase Dbp5 in cytoplasmic quality control
Nov 11, 2022
EV Fingerprinting: Resolving extracellular vesicle heterogeneity using multi-parametric flow cytometry
Nov 11, 2022
Ciliary tip actin dynamics regulate the cadenceof photoreceptor disc formation
Nov 11, 2022
Quantifying spatial dynamics and regulators of Mycobacterium tuberculosis phagocytosis by primary human macrophages using microfabricated patterns
Nov 11, 2022
Radical pair based magnetic field effects in cells: the importance of photoexcitation conditions and single cell measurements
Nov 10, 2022
Inhibiting ribosome assembly and ribosome translation have distinctly different effects on the abundance and paralogue composition of ribosomal protein mRNAs in Saccharomyces cerevisiae
Nov 10, 2022
Automated segmentation and quantitative analysis of organelle morphology, localization and content using CellProfiler
Nov 10, 2022
Adaptive preservation of orphan ribosomal proteins in chaperone-stirred condensates
Nov 10, 2022
Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair
Nov 10, 2022
Survivin is a mechanosensitive cell cycle regulator in vascular smooth muscle cells
Nov 10, 2022
Cdc42 regulates cytokine expression and trafficking in bronchial epithelial cells
Nov 10, 2022
The FXR agonist obeticholic acid does not stimulate liver regeneration in hepatectomized mice.
Nov 10, 2022
Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics
Nov 10, 2022
Development of a mouse model for postresectional liver failure.
Nov 10, 2022
Stepwise modifications of transcriptional hubs link pioneer factor activity to a burst of transcription
Nov 09, 2022
Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes
Nov 09, 2022
Live Imaging of Cutaneous Wound Healing in Zebrafish
Nov 08, 2022
Transcriptomic balance and optimal growth are determined by cell size
Nov 08, 2022
SIRT6 is a key regulator of mitochondrial function in the brain
Nov 08, 2022
The AMPK-TORC1 signalling axis regulates caffeine-mediated DNA damage checkpoint override and cell cycle effects in fission yeast
Nov 08, 2022
Segregation of pathways leading to pexophagy
Nov 08, 2022
Microtubule binding-induced allostery promotes LIS1 dissociation from dynein prior to cargo transport
Nov 08, 2022
Kinesin family motors modify transcription mediated by ERR1 using a conserved nuclear receptor box motif
Nov 08, 2022
Choice of friction coefficient deeply affects tissue behaviour in epithelial vertex models
Nov 07, 2022
A novel pathway of functional microRNA uptake and mitochondria delivery
Nov 07, 2022
Temporal inhibition of electron transport chain attenuates stress-induced cellular senescence by prolonged disturbance of proteostasis in human fibroblasts
Nov 07, 2022
The transcriptional repressor Opi1 modulates the DNA Damage Response by downregulation of inositol pyrophosphates in Saccharomyces cerevisiae
Nov 07, 2022
The septate junction component Bark beetle is required for Drosophila intestinal barrier function and homeostasis
Nov 07, 2022
GDF3 simultaneously antagonizes BMP signaling and activates TGFβ receptor signaling
Nov 07, 2022
Kinetochore microtubules flux poleward along fixed centrosome-anchored microtubules during the metaphase of C. elegans one-cell embryo.
Nov 07, 2022
Two RhoGEF isoforms with distinct localisation act in concert to control asymmetric cell division
Nov 06, 2022
Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor
Nov 06, 2022
Actin filaments accumulate in the nucleus during interphase and remain in the vicinity of condensing chromosomes during prophase to metaphase in zebrafish early embryos
Nov 06, 2022
Defects in lipid homeostasis reflect the function of TANGO2 in Acyl-CoA metabolism
Nov 05, 2022
Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA scanning and recruitment to oxidized bases in living cells
Nov 05, 2022
Reducing mitochondrial ribosomal gene expression does not alter metabolic health or lifespan in mice
Nov 05, 2022
The MuSK-BMP pathway maintains myofiber size in slow muscle through regulation of Akt-mTOR signaling
Nov 05, 2022
Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier
Nov 04, 2022
Oocytes can repair DNA damage during meiosis via a microtubule-dependent recruitment of CIP2A-MDC1-TOPBP1 complex from spindle pole to chromosomes
Nov 04, 2022
Phosphoproteomic profiling highlights CDC42 and CDK2 as key players in the regulation of the TGF-β pathway in ALMS1 and BBS1 knockout models
Nov 04, 2022
Vitamin B5, a Coenzyme A precursor, rescues TANGO2 deficiency disease associated defects in Drosophila and human cells
Nov 04, 2022
V0-ATPase downregulation induces MVID-like brush border defects independently of apical trafficking in the mammalian intestine
Nov 04, 2022
Spatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function
Nov 04, 2022
Insights into cargo sorting by SNX32 in neuronal and non-neuronal cells: physiological implications in neurite outgrowth
Nov 04, 2022
IGF2BP2 is Induced by Stress in the Heart and Mediates Dilated Cardiomyopathy
Nov 04, 2022
Optogenetic control of YAP can enhance the rate of wound healing
Nov 04, 2022
Integrated transcriptome and lineage analyses reveal novel catecholaminergic cardiomyocytes contributing to the cardiac conduction system in murine heart
Nov 04, 2022
Organelle-specific photoactivation and dual-isotope labeling strategy reveals phosphatidylethanolamine metabolic flux
Nov 04, 2022
SOX9 elongates cell cycle phases and biases fate decisions in human intestinal stem cells
Nov 04, 2022
Loss of Mfn1 but not Mfn2 enhances adipogenesis
Nov 04, 2022
Neurons Alter Endoplasmic Reticulum Exit Sites to accommodate Dendritic Arbor Size
Nov 04, 2022
Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation
Nov 03, 2022
Differentiation is accompanied by a progressive loss in transcriptional memory
Nov 03, 2022
SUMOylation regulates Lem2 function in centromere clustering and silencing
Nov 03, 2022
Unraveling the Intricate Cargo-BBSome Coupling Mechanism at the Ciliary Tip
Nov 03, 2022
Regeneration in calcareous sponge relies on 'purse-string' mechanism and the rearrangements of actin cytoskeleton
Nov 02, 2022
P bodies coat germ granules to promote transgenerational gene silencing in C. elegans
Nov 02, 2022
The IgCAM CAR regulates gap junction mediated coupling on embryonic cardiomyocytes and affects their beating frequency
Nov 02, 2022
Isolation of Extracellular Vesicles from human plasma samples: The importance of controls
Nov 02, 2022
Subscaling of a cytosolic RNA binding protein governs cell size homeostasis in the multiple fission alga Chlamydomonas
Nov 02, 2022
Loss of the centrosomal protein ALMS1 alters lipid metabolism and the regulation of extracellular matrix-related processes
Nov 02, 2022
Early endosomes act as local exocytosis hubs to repair endothelial membrane damage
Nov 02, 2022
PARK15/FBXO7 is dispensable for PINK1/Parkin-dependent mitophagy in iNeuron and HeLa cell systems
Nov 02, 2022
Primordial germ cells adjust their protrusion type while migrating in different tissue contexts in vivo
Nov 02, 2022
OpenFIBSEM: an application programming interface for easy FIB/SEM automation
Nov 02, 2022
Validation of species-specificity of two commercial antibodies directed against RILP (Rab-interacting lyosomal protein).
Nov 02, 2022
AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion
Nov 02, 2022
Intracellular calcium elevations drive the nucleation of FIP200- and ATG13-containing pre-autophagosomal structures that become omegasomes
Nov 02, 2022
The midbody and midbody remnant are assembly sites for RNA and active translation
Nov 02, 2022
Copper-independent lysosomal localization of the Wilson disease protein ATP7B
Nov 01, 2022
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing Mcl-1-addicted cancer cells
Nov 01, 2022
Label free autofluorescence imaging permits comprehensive and simultaneous assignment of cell type identity and reveals the existence of airway secretory cell associated antigen passages (SAPs).
Nov 01, 2022
Lomasomes and other fungal plasma membrane macroinvaginations have a tubular and lamellar genesis
Nov 01, 2022
Synchronized proinsulin trafficking reveals delayed Golgi export accompanies beta-cell secretory dysfunction in a rodent model of hyperglycemia
Nov 01, 2022
An Iron-Calcium-Miro Axis Influences Parkinson Risk and Neurodegeneration
Nov 01, 2022
Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein
Nov 01, 2022
Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development
Nov 01, 2022
Allosteric inhibition of the epidermal growth factor receptor through disruption of transmembrane interactions
Nov 01, 2022
The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
Nov 01, 2022
Chronological aging impacts abundance, function and microRNA content of extracellular vesicles produced by human epidermal keratinocytes
Nov 01, 2022
USP10 strikes down Wnt/β-catenin signaling by dual-wielding deubiquitinase activity and phase transition potential
Nov 01, 2022
Polarity and mixed-mode oscillations may underlie different patterns of cellular migration
Nov 01, 2022
Lipid peroxidation increases membrane tension, Piezo1 gating and cation permeability to execute ferroptosis
Oct 31, 2022
LSR Targets YAP to Modulate Intestinal Paneth Cell Differentiation
Oct 31, 2022
SHIP2 controls matrix mineralization by regulation of the RhoA/ROCK pathway and remodeling of the actin cytoskeleton
Oct 31, 2022
Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ears
Oct 31, 2022
Different biological effects of exposure to far-UVC (222 nm) and near-UVC (254 nm) irradiation
Oct 31, 2022
Excitable dynamics in a molecularly-explicit model of cell motility: Mixed-mode oscillations and beyond
Oct 30, 2022
Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids
Oct 30, 2022
Spatiotemporal coordination of stem cell behavior following alveolar injury
Oct 30, 2022
Distinct Wolbachia localization patterns in oocytes of diverse host species reveal multiple strategies of maternal transmission
Oct 30, 2022
Intercellular crosstalk in adult dental pulp is mediated by heparin-binding growth factors Pleiotrophin and Midkine
Oct 29, 2022
Using the AKAR3-EV biosensor to assess Sch9- & PKA-signalling in budding yeast
Oct 29, 2022
An inducible explant model for dissecting osteoclast-osteoblast coordination in health and disease.
Oct 28, 2022
The Novel Role of Midbody-Associated mRNAs in Regulating Abscission
Oct 28, 2022
Mechanical force induces DRP1-dependent asymmetrical mitochondrial fission for quality control
Oct 28, 2022
Phosphate Starvation Signaling Increases Mitochondrial Membrane Potential through Respiration-independent Mechanisms
Oct 27, 2022
Endothelial cells release microvesicles that harbor multivesicular bodies and secrete exosomes
Oct 27, 2022
A cellular and transcriptomic dissection of the human breast for studying mechanisms of cell and tissue function
Oct 27, 2022
Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest
Oct 27, 2022
Lipid homeostasis is essential for a maximal ER stress response
Oct 27, 2022
MUC13 negatively regulates tight junction proteins and intestinal epithelial barrier integrity via Protein Kinase C
Oct 27, 2022
Membrane curvature-generating proteins crucial for autophagosome formation
Oct 27, 2022
Targeting IRS-1/2 in uveal melanoma inhibits in vitro cell growth, survival and migration, and in vivo tumor growth.
Oct 26, 2022
Quantitative super-resolution imaging of platelet degranulation reveals differential release of VWF and VWF propeptide from alpha-granules
Oct 26, 2022
LARP4 Is an RNA-Binding Protein That Binds Nuclear-Encoded Mitochondrial mRNAs To Promote Mitochondrial Function
Oct 26, 2022
Hsp47 Promotes Biogenesis of Multi-subunit Neuroreceptors in the Endoplasmic Reticulum
Oct 26, 2022
YAP condensates are highly organized hubs for YAP/TEAD transcription
Oct 26, 2022
Surface protein profiling of milk and serum extracellular vesicles unveil body fluid and cell-type signatures and insights on vesicle biogenesis
Oct 24, 2022
SORORIN is an evolutionary conserved antagonist of WAPL
Oct 24, 2022
An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion
Oct 24, 2022
Survivin Regulates Intracellular Stiffness and Extracellular Matrix Production in Vascular Smooth Muscle Cells
Oct 24, 2022
UBAP2L-dependent coupling of PLK1 localization and stability during mitosis
Oct 24, 2022
STIM1 signals through NFAT independently of Orai1 and SOCE to regulate breast cancer cell migration
Oct 23, 2022
miR-148a-3p inhibits osteogenesis by targeting Itga11 via PI3K/Akt/GSK3/β-catenin pathway
Oct 23, 2022
Condensin dysfunction is a reproductive isolating barrier in mice
Oct 21, 2022
The male mouse meiotic cilium emanates from the mother centriole at zygotene prior to centrosome duplication
Oct 21, 2022
TGF-β and BMP subfamily pathways in zebrafish spermatogonial niche: A83-01 and DMH1 inhibitor effects in spermatogonial self-renewal and differentiation
Oct 21, 2022
Species-specific roles for the MAFA and MAFB transcription factors in regulatingislet β cell identity
Oct 21, 2022
Synaptotagmin-9 and Tomosyn-1 molecular complex regulates Stx1A SNAREs to inhibit insulin secretion from pancreatic beta-cells
Oct 21, 2022
Zebrafish Rif1 Impacts Zygotic Genome Activation, Replication Timing, and Sex Determination
Oct 21, 2022
Mitotic chromosomes scale to nucleo-cytoplasmic ratio and cell size in Xenopus
Oct 21, 2022
Insights into H2O2-induced signaling in Jurkat cells from analysis of gene expression
Oct 21, 2022
TORC1 is an essential regulator of nutrient-dependent differentiation in Leishmania
Oct 21, 2022
ROCK2 Knockout Improves Proliferation Rate in a Cellular Model of Down Syndrome
Oct 21, 2022
PP2A-B55α controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus
Oct 20, 2022
Extracellular matrix stiffness regulates fibroblast differentiation by influencing DNA methyltransferase 1 expression through microtubule polymerization
Oct 20, 2022
Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting beta cell differentiation
Oct 20, 2022
SARS-CoV-2 infected cells sprout actin-rich filopodia that facilitate viral invasion
Oct 20, 2022
SARS-CoV2 E and 3a proteins are inducers of pannexin currents
Oct 20, 2022
Patterning of phase-separated condensates by Dnd1 controls cell fate
Oct 20, 2022
Centriolar subdistal appendages promote double strand break repair through homologous recombination
Oct 19, 2022
Prevention of thrombocytopenia and thrombosis in heparin-induced thrombocytopenia (HIT) using deglycosylated KKO: A novel therapeutic?
Oct 19, 2022
MagPEG: a complete extracellular vesicle isolation/analysis solution
Oct 19, 2022
Data-Dependent Acquisition with Precursor Coisolation Improves Proteome Coverage and Measurement Throughput for Label-Free Single-Cell Proteomics
Oct 19, 2022
PSC niche develops into immune-responsive blood cells capable of transdifferentiating into lamellocytes in Drosophila
Oct 19, 2022
Distinct contact guidance mechanisms in single endothelial cells and in monolayers
Oct 19, 2022
RyR2 regulates store-operated Ca2+ entry, phospholipase C activity, and electrical excitability in the insulinoma cell line INS-1
Oct 19, 2022
Structure of a G protein-coupled receptor with GRK2 and a biased ligand
Oct 19, 2022
Long-term, super-resolution HIDE imaging of the inner mitochondrial membrane in live cells with a cell-permeant lipid probe
Oct 19, 2022
RNA structural dynamics modulate EGFR-TKIs resistance through controlling YRDC translation in NSCLC cells
Oct 18, 2022
Morphofunctional evaluation of the adrenal gland in rats submitted to nutritional restriction during pregnancy
Oct 17, 2022
Decoding of YAP levels and dynamics by pluripotency factors
Oct 17, 2022
Rates of global cellular translation and transcription during cell growth and the cell cycle in fission yeast.
Oct 17, 2022
Centrosome amplification fine-tunes tubulin acetylation to differentially control intracellular organization
Oct 17, 2022
The ER tether VAPA is required for proper cell motility and for anchoring ER-plasma membrane contact sites to focal adhesions
Oct 17, 2022
Gaq-PKD/PKCμ regulates the IkB transcription to limit the NF-kB mediated inflammatory response essential for early pregnancy
Oct 17, 2022
Proteomic profiling reveals lysosomal heterogeneity in association with longevity
Oct 17, 2022
The Golgi complex is a regulatory hub for homologous recombination-mediated DNA repair.
Oct 17, 2022
Class IIa HDACs reprogram mitochondrial metabolism to inhibit apoptosis and ferroptosis in response to lipotoxicity
Oct 17, 2022
Opto-RhoGEFs: an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrier strength
Oct 17, 2022
Ploidy modulates cell size and metabolic rate in Xenopus embryos
Oct 17, 2022
Altered cohesin dynamics and histone H3K9 modifications contribute to mitotic defects in the cbf11Δ lipid metabolism mutant
Oct 17, 2022
Cell size contributes to single-cell proteome variation
Oct 17, 2022
Manipulating Oxalate Decarboxylase Provides the Basis of Antilithic Therapy by Acting on the Gut Microbiota
Oct 16, 2022
THE ALLOSTERICALLY MODULATED FREE FATTY ACID RECEPTOR 2 IS TRANSACTIVATED BY AN INCREASE IN THE CYTOSOLIC CONCENTRATION OF CALCIUM IONS
Oct 16, 2022
Selective perijunctional MLCK1 recruitment in Crohn's disease: Identification of essential structural domains
Oct 14, 2022
Metabolite profiling and cytotoxic activity of Andean potatoes: polyamines and glycoalkaloids as potential anticancer agents in human neuroblastoma cells in vitro
Oct 14, 2022
Differential chondrogenic differentiation between iPSC-derived from healthy and OA cartilage is associated with changes in epigenetic and metabolic transcriptomic signatures
Oct 14, 2022
In-cell chemical crosslinking identifies hotspots for p62-IκBα interaction that underscore a critical role of p62 in limiting NF-κB activation through IκBα-stabilization
Oct 14, 2022
Identifying human islet microRNAs associated with donor sex, age and body mass index
Oct 14, 2022
The tendon interfascicular basement membrane provides a vascular niche for CD146+ pericyte cell subpopulations
Oct 14, 2022
Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration
Oct 14, 2022
JADE1 and HBO1/KAT7 proteins in the cytokinesis of epithelial cells. The role of PHD zinc fingers.
Oct 14, 2022
Deubiquitinase USP1 influences the dedifferentiation of mouse pancreatic β-cells
Oct 14, 2022
Peritubular macrophages phagocyte remains of undifferentiated spermatogonia in mouse testis
Oct 14, 2022
Export of discarded splicing intermediates requires mRNA export factors and the nuclear basket
Oct 14, 2022
A Leaky Human Colon Model Reveals Uncoupled Apical/Basal Cytotoxicity in Early Clostridioides difficile Toxin Exposure
Oct 14, 2022
Metabolic rewiring of mitochondria in senescence revealed by time-resolved analysis of the mitochondrial proteome
Oct 14, 2022
The CRL4B E3 ligase regulates mitosis by recruiting phospho-specific DCAFs
Oct 14, 2022
Muscle stem cell function is impaired in absence of Talpid3 - a gene required for primary cilia formation
Oct 14, 2022
IRE-1α is a key switch of pyroptosis and necroptosis in mice by dominating Gasdermin D
Oct 14, 2022
ERK3/MAPK6 dictates Cdc42/Rac1 activity and ARP2/3-dependent actin polymerization
Oct 13, 2022
Alterations in platelet proteome signature and impaired platelet integrin αIIbβ3 activation in patients with COVID-19
Oct 12, 2022
Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation
Oct 12, 2022
Development of novel cytoprotective small compounds inhibiting mitochondria-dependent apoptosis
Oct 12, 2022
Endosomal Trafficking of Two Pore K+ Efflux Channel TWIK2 to Plasmalemma Mediates NLRP3 Inflammasome Activation and Inflammatory Injury
Oct 12, 2022
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
Oct 12, 2022
Endosomal removal and disposal of dysfunctional, immunostimulatory mitochondrial DNA
Oct 12, 2022
The kleisin subunit controls the function of meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1
Oct 12, 2022
A genome-wide CRISPR interference screen using an engineered trafficking biosensor reveals a role for RME-8 in opioid receptor regulation
Oct 11, 2022
Uterine histotroph and conceptus development. III. Adrenomedullin stimulates proliferation, migration and adhesion of porcine trophectoderm cells via AKT-TSC2-MTOR cell signaling pathway.
Oct 11, 2022
Lis1 relieves cytoplasmic dynein-1 auto-inhibition by acting as a molecular wedge
Oct 11, 2022
FBXL4 deficiency promotes mitophagy by elevating NIX.
Oct 11, 2022