Longevity Roadmap

By Buck Joffrey

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Category: Health & Fitness

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Subscribers: 14
Reviews: 0
Episodes: 171

Description

Dr. Buck Joffrey sits down with leading scientists in the field of longevity to explore cutting-edge research, emerging therapies, and what it really takes to live longer—healthier.

Episode Date
169: Protein Folding Errors Contribute to Aging and Disease
Jan 05, 2026
168: Best of 2025
Dec 29, 2025
167: Why Bats Don't Age and Why You Should Care with Dr. Emma Teeling
Dec 22, 2025
166: BioXcellerator - The Cutting Edge of Stem Cell Therapy
Dec 15, 2025
165: Improving Cellular Cleanup to Extend Healthspan with Dr. Ana Maria Cuervo
Dec 08, 2025
164: Young Blood Can Rejuvenate Old Brains with Dr. Tony Wyss-Coray
Dec 01, 2025
163: How Mitochondrial Decline Drives Brain Aging with Dr. Francisco Gonzalez-Lima
Nov 24, 2025
162: The Habits of Healthy Aging with Dr. Kate Wolin
Nov 17, 2025
161: The Future of Tissue Regeneration with Dr. Jennifer Elisseeff
Nov 10, 2025
160: Molecular Secrets of Aging Told Through Worms with Dr. Heidi Tissenbaum
Nov 03, 2025
159: How DNA Mutations and Epigenetic Drift Cause Aging with Prof. Jan Vijg
Oct 27, 2025
158: Sitting Is the New Smoking with Dr. Keith Diaz
Oct 20, 2025
157: The Role of Surgery in Diabetes and Obesity with Dr. Mitchell Roslin
Oct 13, 2025
156: Investing in the Business of Aging with Dr. Karl Pfleger
Oct 06, 2025
155: Can Psilocybin Extend Cellular Lifespan? with Dr. Louise Hecker
Sep 29, 2025
154: Is Telomere Length Shortening the Master Switch of Aging? with Dr. Bill Andrews
Sep 22, 2025
153: T Cells, Aging, and Extreme Life Extension with Dr. Derya Unutmaz
Sep 15, 2025
152: The Role of Vitamin A in Brain Health with Prof. Peter McCaffery
Sep 08, 2025
151: Does Astaxanthin Increase Longevity? with Dave Watumull
Sep 01, 2025
150: The Microbiome's Role in Aging and Healthspan with Dr. Sean Gibbons
Aug 25, 2025
149: How Dental Health Impacts Longevity with Dr. Ellie Phillips
Aug 18, 2025
148: Dr. Kevin J. Tracey - Stimulating the Vagus Nerve to Reduce Inflammation and Improve Healthspan
Aug 11, 2025
147: The Wrong Vitamin E Supplement Can Hurt You with Dr. Barrie Tan
Aug 04, 2025
146: AMA President Dr. Bobby Mukkamala - Healthspan-Centric Medical Care in America
Jul 28, 2025
145: Why Some Animals Live Longer Than Others with Dr. Steven Austad
Jul 21, 2025
144: Why the Brain is Especially Vulnerable to Aging with Dr. Julie Andersen
Jul 14, 2025
143: The Longevity Dividend with Prof. Jay Olshansky
Jul 07, 2025
142: The Gut-Muscle Axis with Dr. Michael Lustgarten
Jun 30, 2025
141: A Thermostat for Your Body Fat with Dr. Stephan J. Guyenet
Jun 23, 2025
140: Inside the Inflammatory Clock - Measuring and Reversing Biological Age with Dr. David Furman
Jun 16, 2025
139: Rebuilding the Aging Brain - The Role of Neural Stem Cells with Dr. Tara Walker
Jun 09, 2025
138: Sleep Impact on Longevity and Health with The Sleep Doctor
Jun 02, 2025
137: Dr. Joan Mannick - Targeting mTOR to Improve Immune Function and Healthspan
May 26, 2025
136: Why is Vitamin D So Important in Health and Longevity? with Dr. Michael Holick
May 19, 2025
135: The Aging Brain - From Memory Lapses to Measurable Prevention with Dr. Mitchell Clionsky
May 12, 2025
134: Can You Boost Stem Cells Naturally? with Dr. Christian Drapeau
May 05, 2025
133: Can We Reverse Immune System Aging? T Cells, Telomeres, and the Fight Against Senescence with Dr. Alessio Lanna
Apr 28, 2025
132: Dr. Mark Tarnopolsky's Mitochondrial Cocktail for Cellular Health
Apr 21, 2025
131: Matt Kaeberlein - Aging, mTOR, Epigenetic Clocks, and more!
Apr 14, 2025
130: Does the Gut Control the Brain? with Dr. Michael Gershon
Apr 07, 2025
129: Does Too Much Muscle Shorten Your Life? with Dr. Keith Baar
Mar 31, 2025
128: C15 - The Most Underrecognized Anti-Aging Supplement? with Dr. Stephanie Venn-Watson
Mar 24, 2025
127: The Impact of Depression on Longevity and Healthspan with Dr. Peter Franz
Mar 17, 2025
126: Fahy Protocol - Regrow the Thymus, Reverse Your Age
Mar 10, 2025
125: Reversing Skin Age - Tackling Senescence with OS-01 with Dr. Carolina Reis Olivera
Mar 03, 2025
124: How the Gut Influences Health and Longevity with Dr. Michael Miller and Dr. Jacob Allen
Feb 24, 2025
123: What is Metabolic Dysfunction and Why is it Killing Americans with Dr. Robert Lustig
Feb 17, 2025
122: How Your Taste Buds Shape Metabolic Health with Dr. Marta Yanina Pepino
Feb 10, 2025
121: How Long-Lived Species Could Revolutionize Human Aging with Dr. Vera Gorbunova
Feb 03, 2025
120: Andrea Maier's Personalized Approach to Longevity Medicine with Prof. Andrea B. Maier
Jan 27, 2025
119: What is NAD and How to Boost It for Longevity with Dr. Nicola Conlon
Jan 20, 2025
118: Live to 100 - How To Build Your Personal Blue Zone with Dan Buettner
Jan 13, 2025
117: Best of Longevity Junky 2024
Jan 06, 2025
116: Martin Gibala - The Value of HIIT for Longevity and Healthspan
Dec 30, 2024
115: Dr. Ellen Langer - The Mind-Body Connection
Dec 23, 2024
114: Traditional Lab Studies Can Miss Deadly Disease
Dec 16, 2024
113: Lipid Management with Coronary Artery Disease and e2/e4 Genotype
Dec 09, 2024
Giveaway: $2500 Full-Body MRI
Dec 02, 2024
112: Longevity Escape Velocity with Aubrey de Grey
Dec 02, 2024
🎁 The Gift of Longevity – Black Friday & Cyber Monday Special!
Nov 30, 2024
111: Nanoparticles in Neurodegenerative Disease Treatment
Nov 25, 2024
110: Unique Framework for Nutrition and Longevity with Dr. David Raubenheimer and Prof. Stephen Simpson
Nov 18, 2024
109: Red Light in Mitochondrial Health with Prof. Glen Jeffery
Nov 11, 2024
108: Diving Deep on Lipids and Heart Disease with Dr. Dennis Hughes
Nov 04, 2024
Do You Have Your Longevity Roadmap?
Oct 28, 2024
107: Longevity Supplements - The Novos Approach
Oct 28, 2024
106: Nitric Oxide - The X Factor in Longevity? with Dr. Nathan Bryan
Oct 21, 2024
105: Understanding Heart Rate Variability with Dr. Torkil Færø
Oct 14, 2024
104: The Real Science Behind Mitochondrial Health
Oct 07, 2024
103: Microplastics and Your Health - One More Thing to Worry About
Sep 30, 2024
102: Everything You've Been Told About Fat Loss is a Lie – Layne Norton Exposes the Truth
Sep 23, 2024
101: Can we see mental illness on brain scans?
Sep 16, 2024
100: What is Flow?
Sep 09, 2024
99: What is a Retinal Detachment? A First Person Narrative
Sep 02, 2024
98: Big Tech's Vision of an Aging Population
Aug 26, 2024
97: Buck's Boston Heart Cholesterol Balance Test
Aug 19, 2024
96: Cardiovascular Risk Management: Calcium Scores, Lp(a), and Colchicine
Aug 12, 2024
95: What is Atherosclerosis and How to Prevent it
Aug 05, 2024
94: Intermittent vs Prolonged Fasting
Jul 29, 2024
93: Alzheimer's Disease vs Age-Related Cognitive Decline
Jul 22, 2024
92: Gene Editing 101
Jul 15, 2024
91: Ask the Doctor 07/08
Jul 08, 2024
90: Ask the Doctor 07/01
Jul 01, 2024
89: The Nine Pillars of Resilience with Stephen Sideroff, PhD
Jun 24, 2024
88: Stem Cells - Myth vs Reality with Hans Keirstead, PhD
Jun 17, 2024
87: The Longevity Clinic Paradigm
Jun 10, 2024
86: The Science of Human Attraction
Jun 03, 2024
85: Fasting, Protein, and Full Body MRI with Dr. Matt Brill
May 27, 2024
84: Keto Diet 101
May 20, 2024
83: Sexually Transmitted Cancer
May 13, 2024
82: Intro to the Microbiome
May 06, 2024
81: Ask the Doctor 04/29/24
Apr 29, 2024
80: The Longevity Diet with Valter Longo, PhD
Apr 22, 2024
79: Lies Taught in Medical School: Robert Lufkin, M.D.
Apr 15, 2024
78: The Age of Data-Driven Wellness is Here
Apr 08, 2024
77: Ask the Doctor (April Fools Edition)
Apr 01, 2024
76: Intermittent Fasting Correlated to Higher Risk of Cardiovascular Death
Mar 25, 2024
75: Stress, Cortisol and Prevention Strategies
Mar 18, 2024
74: Aggressive Male TRT Approach, Erectile Dysfunction Drugs, and Alzheimer's Disease
Mar 11, 2024
73: Is a Vegan Diet Healthy?
Mar 04, 2024
72: A Different Framework for Health?
Feb 26, 2024
71: Ask the Doctor 02/19
Feb 19, 2024
70: The Science Behind Music and Mental Health
Feb 12, 2024
69: Glutathione: The Master Antioxidant
Feb 05, 2024
68: Food Allergy 101 with Tina Sindher, MD
Jan 29, 2024
67: The Silent Global Epidemic Killer
Jan 22, 2024
66: What is the common cold and how do you treat it?
Jan 17, 2024
65: Aging Skin and How to Fight It
Jan 15, 2024
63: A Look Back at 2023
Jan 01, 2024
62: Ask the Doctor 12/25
Dec 25, 2023
61: Wisdom Wednesday: Surviving vs Winning
Dec 20, 2023
60: Inflammaging
Dec 18, 2023
59: How Much Exercise Is Too Much For Longevity?
Dec 13, 2023
58: A Review on the Risks and Benefits of Human Growth Hormone Supplementation
Dec 11, 2023
57: How Stress Impacts Your Body
Dec 06, 2023
56. Ask the Doctor (December 2023)
Dec 04, 2023
55: Engaging Your Subconscious For Success
Nov 29, 2023
54: What Supplements Does Buck Take?
Nov 27, 2023
53: How to Avoid Blood Clots During Holiday Travel
Nov 22, 2023
52: What You Need to Know About Protein and Longevity
Nov 20, 2023
51: Part 2: Alzheimers's Disease: Risk Factors, Prevention and Treatment
Nov 15, 2023
50: Part 1: Alzheimers's Disease: Risk Factors, Prevention and Treatment
Nov 13, 2023
49: 3 Eating Tips to Live Longer
Nov 08, 2023
48: Living Longer for Busy People
Nov 06, 2023
47: Exercising for Longevity and More with Dr. Tom Walters | 2 of 2
Nov 01, 2023
46: Exercising for Longevity and More with Dr. Tom Walters | 1 of 2
Oct 30, 2023
45: WHEN to Sleep to Reduce Your Risk of Alzheimer's Disease
Oct 25, 2023
44: This Old Gout Drug May Help You Live Longer
Oct 23, 2023
43: Make This One Simple Change To Improve Your Sleep
Oct 18, 2023
42: Ask The Doctor
Oct 16, 2023
41: FDA Panel: Popular Cold Medicine Doesn't Work
Oct 11, 2023
40: Full Body MRI: Avoiding Health Time Bombs
Oct 09, 2023
39: Tipping the Scales: A Closer Look at Wegovy & Ozempic for Weight Loss
Oct 04, 2023
38: What is your TRUE age? Biological VS Chronological
Oct 02, 2023
37: Psilocybin: Evidence that a Psychedelic May Treat Depression
Sep 27, 2023
36: Cold Therapy: Real Science or Cool Trend?
Sep 25, 2023
35: Is Hearing Loss Connected to Dementia?
Sep 20, 2023
34: Female Sexual Dysfunction
Sep 18, 2023
33: The Cutting Edge Science of Age Reversal - Part 2
Sep 13, 2023
32: The Cutting Edge Science of Age Reversal - Part 1
Sep 11, 2023
31: What Covid does to your Brain
Sep 06, 2023
30: What's Your Risk of Getting Alzheimer's Disease?
Sep 04, 2023
29: Male Sexual Health - Part 2
Aug 30, 2023
28: Male Sexual Health - Part 1
Aug 28, 2023
27: Yamanaka Factors - Can Aging Be Reversed?
Aug 23, 2023
26: Ask The Doctor P2 of 2
Aug 21, 2023
25: Heart Rate Variability (HRV)
Aug 16, 2023
24: Ask The Doctor P1 of 2
Aug 14, 2023
23: Jet Lag and Melatonin
Aug 09, 2023
22: Battle of Cardio IQs Part 2
Aug 07, 2023
21: Why Did Bronny James Collapse?
Aug 02, 2023
20: Battle of Cardio IQs Part 1
Jul 31, 2023
19: Snoring and Sleep Apnea: Just Noise or Silent Killers?
Jul 26, 2023
18: Could This Simple Blood Test Revolutionize Early Cancer Detection?
Jul 24, 2023
17: Is Your Diet Coke Killing You?
Jul 19, 2023
16: Ask the Doctor
Jul 17, 2023
15: Essentials of Female Hormone Replacement
Jul 13, 2023
14: Essentials of Male Hormone Replacement
Jul 12, 2023
13: Reprogramming Your Brain with Ketamine and Psychedelics: Part 2
Jul 05, 2023
12: Reprogramming Your Brain with Ketamine and Psychedelics: Part 1
Jul 04, 2023
11: Fountain of Youth or Just a Dry Sauna?
Jun 28, 2023
10: Longevity Pillar 6: Being Social Helps You Live Longer
Jun 26, 2023
9: Taurine: An Ingredient in Energy Drinks that May Add Years to Your Life!
Jun 21, 2023
8: Longevity Pillar 5: Personalized Diagnostics to Monitor Your Own Health
Jun 19, 2023
7: Metformin: Miracle Longevity Drug or Hype?
Jun 15, 2023
6: Longevity Pillar 4: Taking Drugs That Can Help You Live Longer
Jun 12, 2023
5: Longevity Pillar 3: Sleeping to Live Longer and Healthier
Jun 05, 2023
4: Longevity Pillar 2: Exercise THE RIGHT WAY!
May 29, 2023
3: Why Hyperglycemia is a KILLER (and what to do about it)
May 26, 2023
2: Longevity Pillar 1: What to Eat and When
May 20, 2023
1: An Introduction to Sapio
May 19, 2023