A Dose of Reality with Charles Spence

By Charles Spence

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Category: Careers

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Episodes: 61

Description

Welcome to “A Dose of Reality”, the podcast where we infuse insight, laughter, and practical wisdom into the world of clinical leadership and career development. Hosted by Charles Spence, each episode offers a deep dive into the challenges and triumphs of clinical leadership, providing listeners with meaningful conversations, career insights, and a dose of inspiration to navigate their professional journeys. Whether you're a director, a C-level executive, or a clinical researcher in oncology bio-techs, this podcast is designed to empower you with the knowledge and tools needed to excel in your field. So, visit our website at www.discera-search.com, and tune in to A Dose of Reality for your prescription of career wisdom, leadership insights, and a healthy dose of laughter.  Subscribe now and join us on the journey to becoming global clinical leaders!

Episode Date
Sven Van den Berghe, CEO of Pantera on Overpromises in Isotope Marketing, Why Culture is the Company, and Discussions in RLT Development
Nov 17, 2025
Catello Somma, Partner at Seroba on Working in VC, Non-Linear Biotech Careers, and advice for those seeking VC careers
Nov 10, 2025
Kevin N. Heller, MD, Chief Medical Officer and Advisor to Funds and VCs, on Culture Shifts, Tough Lessons In Leadership, And The Reality Of Biotech Fundraising
Oct 27, 2025
Carl Deutsch, CSO at NBE Therapeutics in Non-Linear Careers, Age Bias, and Building Great Teams
Oct 13, 2025
Aleksandra Filipovic, Chief Medical Officer at Gallop Oncology on Perfectionism, Intuition, and the Risk of Building Unsafe Teams
Oct 06, 2025
Heidi Wang, CEO at OBI Pharma & Chairwoman at OBIGEN Pharma on Losing Her Father to Cancer, Hiring Without Humility, and Building a Culture That Lasts
Sep 21, 2025
András Strassz, MD, MBA, CMO at Heidelberg Pharma – Career Crossroads, Recruiting, and Culture Fit Over CVs
Aug 13, 2025
Steven Katz, MD, CMO and SVP of Translational Science for Shinobi Therapeutics & Professor of Surgery at Brown University - Hiring Without Regret, Team Mismatches, and the Cost of Playing It Safe in Biotech
Aug 04, 2025
Christian Mueller, CDO at Immutep on Career Crossroads, Culture Missteps, and the Recruitment Disconnect in Biotech
Jul 28, 2025
Kirsty Crame-van Nierop, Director of Shiaba Consulting, Specialist on Clinical Drug Development, in Broken Hiring Cycles, IND Wins, and Surviving Biotech Burnout
Jul 14, 2025
Bernhardt Zeiher, M.D. Member of the board of directors for Entrada Therapeutics, Amylyx Pharmaceuticals, and Abeona Therapeutics on Lessons from Leading a Global Development Organization
Jun 30, 2025
Ilya Gipp, CMO at GE Healthcare – Imaging’s Role in Oncology, Hiring Lessons, and How Culture Really Works
Jun 16, 2025
Michael Lahn, CMO at iOnctura – Osimertinib Success, TGF-Beta Lessons, Building Curious Teams, and More
Jun 09, 2025
Johan Baeck, EVP and CMO at Promontory Therapeutics – Cultural Fit in Hiring, Immunogenic Small Molecules, and Building Resilience in Biotech
May 28, 2025
Peter Tummino, President of R&D at Nimbus Therapeutics – Drugging the Undruggable, The TYK2 Success Story, and Overhyping AI in Drug Discovery
May 12, 2025
Abigail Jenkins, CEO and Board Member – From Government Scientist to CEO, Launching a Stem Cell Therapy During Crisis, and Lessons in Commercial Strategy
May 06, 2025
Joseph Birkett, Executive Director at Aura Biosciences – Obinutuzumab's Approval, CDK9 Trial Regret, CRO Reliance, and Building Respectful Cultures
Apr 27, 2025
Bruce Dezube, Senior Vice President, Clinical Development at Xilio Therapeutics – HIV & Cancer Drug Development, Career at 60, Building Respectful Teams, and More
Apr 22, 2025
Chris Lowe, CEO at Nusano - Radioisotopes, Volunteering in Hospitals, Culture Building, and More
Apr 07, 2025
Kevin Lynch, co-Founder PopulusBio - Career at Celgene, How Culture Influences Drug Development and more
Mar 24, 2025
Victor Paulus, SVP Regulatory Affairs at ARTBIO - Lutathera Approval and Lessons, Falling from Trees, ARTBIO's Culture
Mar 17, 2025
Chris Leamon, CSO at Fusion Therapeutics - Acquisition of Endocyte, Career reflections and more
Feb 17, 2025
Dawn Rubel, Dawn Rubel, President R&D at NexEos Bio - Eosinophilic Esophagitis, Purposeful Leadership and more
Feb 10, 2025
Örn Almarsson, Co-Founder of Axelyf - Modernas SpikeVax, the challenge of mRNA delivery and Salmon's inspiration behind Axelyf?
Feb 03, 2025
Leila Jaafar, CEO at Nuclidium - from PhD to Radiotherapy CEO
Jan 27, 2025
CMO at Indaptus, Roger Waltzman, on Dangers of Pushing Uncertain Data into Phase III
Jan 20, 2025
Gertjan Bartlema, Co-founder Populus Bio and CEO of Immodulon Therapeutics. on Innovation in Biotechs
Jan 08, 2025
The 3 Most Common Rejection Reasons During an Interview
Dec 30, 2024
The Most Common Hiring Mistakes by Hiring Managers in 2024 ft. Caroline Vermeulen, Eminence
Dec 16, 2024
How and When to Ask Intelligent Interview Questions
Dec 09, 2024
Troels Jordansen, Executive Chairman of Keli Therapeutics, on Cell Therapy and Biotech Recession Talks
Dec 02, 2024
Negotiation Strategies and Insights from Harvard Course ft. Sophie He, Head of M&A and Partnering at Bracco
Nov 25, 2024
The 3 Interview Questions You Must Succeed In
Nov 18, 2024
Nikolaus Trede, SVP Clinical Development at Century Therapeutics - Lessons from Breyanzi and Global Cell Therapy Trials
Nov 12, 2024
Re-Entering the Workforce and Career Growth in Regulatory Affairs with Mary Christian
Sep 09, 2024
From Neuroscientist to Biotech Innovator ft.Anita Scheuber
Sep 02, 2024
Future-Proofing Your Organization Ft. Jackie Donovan
Aug 26, 2024
The Critical Role of Recruiters ft. Patrizio Renzetti
Aug 19, 2024
Bad Science vs. Good Leadership in Biotech ft. Sonal Kothari-Gupta, MD, PhD
Aug 12, 2024
Recruitment Strategies for High-Impact Hires with John Goldener
Aug 05, 2024
Hiring Strategies for Biotech Success ft. Sumeet Ambarkhane CMO at Alligator Bioscience
Jul 29, 2024
How to Outsource Your Job Search
Jul 22, 2024
Stealth biotech work, moving China trials to the US and more ft. Li Yan, former CMO of Brii and current CEO of upcoming stealth biotech
Jul 15, 2024
Building powerful relationships ft. Val Nassiri, previous VP of Medical Affairs at ITM and AAA.
Jul 08, 2024
Using Empathy to Build Internal Support
Jul 01, 2024
Sabine Brookman May VP Janssen - Listening in leadership, making beer and a career in drug development
Jun 24, 2024
The Biggest Selling Myth: Selling Through Talking
Jun 17, 2024
Effective Layoffs and treating people as humans ft. Crystal Zuckerman
Jun 10, 2024
Improve Your Selling Ability to Help Your Career
Jun 03, 2024
BIOSECURE Act - The potential $3.6bn+ gap, Impact on Jobs and Skills shifts with Amber Tong, Senior Editor at EndPoint News
May 27, 2024
My 10 Commandments to Recruitment
May 20, 2024
Discussions on Leadership, Hard decisions and Radiotherapy Ft. Collin Hayward, former CMO of Telix Pharma
May 13, 2024
3 Ways to Protect Your Reputation as a Hiring Manager
May 06, 2024
The Big Picture - Discussing Clinical Entry to Commercial Planning in Radiotherapy With Ben Pais, SVP Aricieum
Apr 29, 2024
Creating Shit Hot Authentic Stories to Sell Your Achievements
Apr 22, 2024
Discussing radiotherapy, AAA and CEO leadership with Riccardo Canevari: CEO of Radiopharm Theranostics
Apr 15, 2024
Radiotherapy 2024: Quick Look into the Radiotherapy Landscape
Apr 08, 2024
Ilaria Conti VP ADC Therapeutics - Female Leadership, Challenges in ADCs and Working in the US
Apr 01, 2024
Masterful Salary Negotiations: Less Fear, More Preparations and Get More of What You Want
Apr 01, 2024
Mats Hansen, CEO Spago Nanomedical: How to Lead a Radiotherapy Biotech
Apr 01, 2024
Podcast Trailer
Mar 14, 2024