Behind the Breakthroughs

By Inside Precision Medicine

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Episodes: 41

Description

Join host Jonathan D. Grinstein, PhD, North American Editor for Inside Precision Medicine, as he uncovers the stories behind the pioneers driving the precision medicine revolution. Behind the Breakthroughs features candid interviews with seasoned veterans and rising stars, exploring their origin stories and groundbreaking contributions advancing the frontiers of patient diagnosis, treatment, and care.


In every episode, Jonathan goes beyond the science, diving deep into the personal and professional journeys of those striving to make these incredible new therapies more equitable and accessible globally. You'll discover how emerging technologies in molecular diagnostics, next-generation sequencing, genetic medicines (e.g., cell and gene therapies), and AI/ML are transforming treatment and bringing precision medicine closer to the forefront of healthcare. Whether you’re a researcher at a large pharma company or small biotech startup, a clinician at a major health system or community setting, a laboratory technician in the clinic or academia, an investor at a premier or venture capital firm, or just interested in the latest in medicine and healthcare, these interviews will inspire and inform you about personalized medicine's future.


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Episode Date
Matthew Rabinowitz: Engineering a New Era of Diagnosis
May 06, 2026
Jurgi Camblong: Data-Driven Doctors Without Borders
Apr 22, 2026
Molly Gibson: Superintelligence and the Future of Drug Development
Apr 08, 2026
Mike Curtis: Pig Organs as a Bridge to Human Transplants
Mar 25, 2026
Markus Warmuth: Eliminating Pathogenic Proteins with Molecular Glue Degraders
Mar 11, 2026
Alicia Zhou: The Dark Matter for Cancer Immunotherapy Translation
Feb 25, 2026
Brad Ringeisen: CRISPR for Disease Elimination and Humanitarian Solutions
Feb 11, 2026
Zachary Roberts: Building a Viable Off-the-Shelf CAR T
Jan 28, 2026
Boyang Wang: Organ Swaps and Mass Preventative Gene Therapy to Extend Lifespan
Jan 07, 2026
Year In Review: My Personal Genomics Journey Redux
Dec 17, 2025
David Fischel: Surgical Robotics for Superhuman and Remote Operations
Dec 03, 2025
Katherine Stueland: The Diagnostic Odyssey Era Ends with Early Genomics
Nov 19, 2025
Rahul Gupta: Can Biotech Fix U.S. Healthcare Faster than Policy?
Nov 12, 2025
Michael Langer: Biotech Investing in the Data Age
Oct 29, 2025
Vanessa Almendro-Navarro: Baby KJ and The Promise of Custom Gene Editing
Oct 15, 2025
Shana Kelley: Instrumented Tissues for Monitoring Human Body In Real-Time
Sep 24, 2025
Mara Aspinall: Taking Diagnostics From Pitch to Patient
Sep 03, 2025
David Liu: Performing Chemistry on DNA to Unlock Personalized Gene Editing
Aug 20, 2025
Janice Chen: Unleashing CRISPR’s Clinical and Diagnostic Potential
Aug 06, 2025
Amber Salzman: Epigenetic Editing Aims to Refine Personalized Genetic Medicine
Jul 23, 2025
Mike Previte: Predicting Biology with Spatiotemporal Multiomics
Jul 09, 2025
Hervé Affagard: Creating Microbiomes to Fight Cancer, ALS, and More
Jun 25, 2025
Michelle Werner: Engineered tRNAs Offer Universal Solutions to Stop Codon Diseases
Jun 11, 2025
Cassie Hajek: Population Genomic Screens Need More Than Pathogenic Variants
May 28, 2025
Patrick Hsu, Serge Saxonov, and Gilad Almogy: Creating the Virtual Cell
May 14, 2025
Kate Sasser: How Lab-in-the-loop Turns Patient Data Into Patient Care
Apr 30, 2025
Kian Sadeghi: Is Personalized Genomics Undergoing a Direct-to-Consumer Renaissance?
Apr 16, 2025
Carlos D. Bustamante: Latin American Diversity’s Genetic Potential
Apr 02, 2025
Josh Denny: The Future of Precision Public Health
Mar 19, 2025
Uli Stilz: Conquering Complex Diseases Affecting Billions with Precision Medicine
Mar 05, 2025
Tomasz (Tom) Beer: Detecting Cancer Before Symptoms? MCED Leads the Way
Feb 19, 2025
Katy Rezvani: Allogeneic NK Cells Are Coming to Beat Cancer at a Clinic Near You
Feb 05, 2025
Toby Ferguson: From Bloodstream to Brain: Accessing the Neurogenetic Medicine Revolution
Jan 22, 2025
Tomi Pastinen: Treating All the Not-So-Rare “Rare Disease” Patients at Major Care Centers
Jan 08, 2025
Tom Whitehead: Not All Precision Medicine Heroes Wear Lab Coats
Dec 18, 2024
Harry Clifford: Carrying Medicine Into the Post-Moore’s Law Era
Dec 04, 2024
Michael Severino: Towards In Vivo Genome Editing of Humans
Nov 21, 2024
Jane Gibson: AMP and Molecular Diagnostics’ Existential Crisis
Nov 13, 2024
Helen Sabzevari: How to Turn $1,000,000 CAR Ts into “Real” Precision Medicines
Oct 30, 2024
Luca Quagliata: Weaving Genomic Profiling into Personalized Cancer Care
Oct 25, 2024
Geoff Oxnard: The Tipping Point for Adopting Precision Medicine
Oct 17, 2024