EP Edge™ The Signal

By Niraj Sharma MD FACC FHRS

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Category: Life Sciences

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Episodes: 11

Description

Monthly clinical deep analysis in cardiac electrophysiology: AF, VT, SVT, ablation, devices, antiarrhythmic drugs, and high-impact trials. The Signal: physician-level analysis that identifies what matters in EP and translates evidence into clinical practice. EP Edge™: The Signal is the flagship monthly podcast from EP Edge, delivering structured, expert-level interpretation for electrophysiologists, cardiologists, fellows, and clinically engaged practitioners. Each episode goes beyond summaries to integrate evidence across trials, guidelines, mechanisms, and real-world practice. Episodes cover the full spectrum of electrophysiology, including atrial and ventricular arrhythmias, supraventricular tachycardias, antiarrhythmic pharmacology, pacing and defibrillator strategies, mapping and ablation technologies (including pulsed field ablation), and emerging data shaping clinical decision-making. This is not a news recap—it is a curated synthesis focused on what truly changes practice. Content combines mechanistic insight, cross-trial evidence review, critical appraisal of methodology and outcomes, and practical application in the EP lab and clinic. EP Edge™: The Signal complements the weekly EP Edge™: Journal Watch by providing deeper analysis and clinical synthesis. For patient-focused education, explore EP Edge™: Heart Talk. Available as both podcast and newsletter via EP Edge on LinkedIn and Substack: https://epedge.substack.com/

Episode Date
EP Edge Newsletter Part III: Pulsed Field Ablation Complications — Hemolysis, Coronary Spasm, Silent Stroke, Phrenic Nerve Injury, and CIED Interaction
Feb 25, 2026
EP Edge Newsletter Part II: Pulsed Field Ablation Trials — ADVENT, PULSED AF, Sphere-9, VARIPULSE, VOLT, INSIGHT, and PULSAR
Feb 18, 2026
EP Edge Newsletter Part I: Pulsed Field Ablation (PFA) — Electroporation, Biophysics, Engineering, Tissue Selectivity, and Lesion Formation
Feb 11, 2026
Cannabis and the Heart: Atrial Fibrillation, Arrhythmias, Stroke, Myocardial Infarction and Sudden Cardiac Risk Explained
Dec 22, 2025
When Atrial Fibrillation Ablation Fails: Have We Reached the Limit or Just the Wrong Target?
Nov 23, 2025
Targeting the Intrinsic Pathway: Is Factor XI Inhibition Poised to Redefine Stroke Prevention in AF: EP Edge August 2025 Issue 4A
Oct 28, 2025
First-Line VT Ablation: Trials, Tools & Timing: EP Edge Newsletter June 2025
Oct 28, 2025
Left Atrial Appendage Occlusion (LAAO): Where We Stand in 2025: EP Edge Newsletter 4B August 2025
Oct 28, 2025
Pulse Field Ablation: Promise, Peril, and the AI Revolution in EP: EP Edge Newsletter May 2025
Oct 28, 2025
Lifestyle Modification and Atrial Fibrillation: Redefining the role of the Electrophysiologist: EP Edge Newsletter July 2025
Oct 28, 2025
Beyond CRT: LBBAP and the New Era of Physiological Pacing — Promise and Pitfalls: EP Edge Newsletter October 2025 Issue 5
Oct 27, 2025