The Human Upgrade with Dave Asprey—formerly Bulletproof Radio

By Dave Asprey

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Subscribers: 3197
Reviews: 3

peter
 Jun 10, 2021
This podcast is 50% ads for authors products

Joe DaSilva
 Mar 15, 2019
Always smart, interesting!

A Podcast Republic user
 Jul 23, 2018

Description

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.

You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.

Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.

Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life. 


Episode Date
The Bacteria That Lets You Drink Alcohol Again – Zack Abbott, Ph.D. : 1000
00:55:48

(ZBiotics sponsored this episode.)

IN THIS EPISODE OF THE HUMAN UPGRADE™…you’ll learn how a new genetically engineered pre-alcohol probiotic drink can stop your hangover before it starts. Great timing as you head into the holiday season of celebrations commonly serving alcohol.

Zack Abbott, CEO & co-founder of ZBiotics, joins this 1,000th episode of the podcast to talk about new discoveries in alcohol metabolism, genetic engineering and GMOs (used in a good way!), and the power of microbes.

Ever wondered why you feel like crap the morning after drinking alcohol? The cause is a byproduct called acetaldehyde that forms in your gut when you drink alcohol. The ZBiotics Pre-Alcohol Probiotic Drink breaks down acetaldehyde while you drink so you can feel better the morning after.

Prior to starting ZBiotics, Zack, who has a Ph.D. in microbiology and immunology, worked in clinical trial design, researched HIV vaccines, and pursued novel antibiotics in both academia and industry.

He invented the ZBiotics proprietary technology using genetic engineering to develop new probiotics—ones with specific, unique abilities to improve your daily life. He’s proving through science that incredible things can be done with GMOs and genetically engineered microbes.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://zbiotics.com/dave and use code "dave" to save 15%.

Watch this episode on YouTube! 

Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale Buster

Harness Cold to Improve Health & Performance: https://www.cryobuilt.com

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Nov 29, 2022
Mini-Episode: Cool Facts Friday #29
00:08:14

In this Episode of The Human Upgrade™...​

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Sperm that swim together increase their chances of fertilization
  • Late-night eating is worse than you thought
  • Metabolic markers can be measured through your sweat
  • Eye movements during REM sleep could delete unwanted memories


EPISODE SPONSOR: Humic & fulvic minerals provide critical cellular support. Go to https://www.beamminerals.com and use code DAVE20 to get 20% off. Learn more: How Minerals Combat Glyphosate’s Harm – Caroline Alan – #948.

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Nov 25, 2022
How Urolithin A Helps Create Super T-Cells & Boosts Immunity – Dr. Anurag Singh : 999
00:50:01

Timeline Nutrition sponsored this podcast.

IN THIS EPISODE OF THE HUMAN UPGRADE™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. 

Urolithin A activates mitophagy and renews your mitochondria.  “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. And so now, you're cleaning your metabolic waste products much more efficiently and they become the building blocks. This is mitochondrial biogenesis, and that means newer, healthy mitochondria coming in.”

This new conversation takes an exciting turn into immunity and your immune system’s two lines of defense: innate and adaptive. You’ll learn:

  • how inflammation plus aging (AKA inflammaging) contributes to a weakened immune system and a growing incidence of cancer as you age;
  • how inflammaging and cancer are connected to mitochondrial dysfunction specifically during the aging process; and
  • how to approach your immune health differently with this new knowledge.


new study recently published in Immunity looks at how immune cells fight cancer better with a focus on immune modulation, immune cell exhaustion and immune responses. “A lot of urolithin A is anti-inflammatory, but a lot of it is immune modulation," Dr. Singh says. "So, it takes a rewiring of the immune system and makes it more conducive to stopping harmful immune responses.”

Watch this episode on YouTube!

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: To learn more about the benefits of urolithin A, go to https://www.timelinenutrition.com and use code UPGRADE10 to get 10% off the plan of your choice. 

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! 

Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. 

Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount

Isometrics for Cardiovascular Healthhttps://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus. 

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Nov 22, 2022
Battling Pathogens and Building Immunity Begins In Your Gut – Dr. Robynne Chutkan : 998
01:17:42

IN THIS EPISODE OF THE HUMAN UPGRADE™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn:

  • how your microbiome continually evolves and why that matters to the state of your gut and body functions.
  • how to strengthen the antiviral defenses located in your gut.
  • why your body’s own ability “to resist, heal, and recover from viruses is vastly superior” to pharmaceuticals.
  • what to do before taking antibiotics to protect your gut, as well as what you can do to rehab your microbiome after antibiotic use.


“Being on the winning team when battling viruses isn’t because of good luck, or coincidence, or variations in viral virulence,” Dr. Chutkan explains in her newest book, “The Anti-Viral Gut: Tackling Pathogens from the Inside Out.” "It’s due to differences in us, the hosts, and our defenses, and those differences are what determine your outcome. Put another way: it’s less about the potency of the pathogen and more about the health of the host.”

Dr. Chutkan is a Yale- and Columbia-educated integrative gastroenterologist who’s been advancing knowledge and education about gut health for decades. Nearly 20 years ago she founded the Digestive Center for Wellness to help people get to the root issue of their digestive issues and improve their gut health. 

Watch this episode on YouTube!

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! 

Brain Training with Sound & Vibration: Change unwanted behaviors, reduce negative self-talk, and enhance motivation and performance. Go to www.braintap.com/dave to get 30% off

Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount.

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Nov 18, 2022
How Sleep Tech Improves Your Performance – Matteo Franceschetti : 997
00:49:25

Eight Sleep sponsored this podcast.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about the intimate relationship between performance and sleep and how you can hack both with a combination of tech and lifestyle. 

Matteo Franceschetti joins the show to talk about high performance—something he experienced in athletics, business and life. He was a competitive athlete in his native Italy and a race car driver across Europe. He started two clean-tech companies on two continents. He also worked at the top tier of the international legal world

The one thing he didn’t excel at was sleep. So, he co-founded Eight Sleep nearly a decade ago to hack sleep in all the ways that fuel human potential, performance and energy.

Eight Sleep mattress and mattress pad technology redesign sleep with AI and machine learning models to track your nighttime biosignals. It’s a technology that’s catching the attention of professional athletes in sports like snowboarding, CrossFit, Formula One, and many more.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.eightsleep.com/dave/ to get up to $450 off a Sleep Fit Holiday Bundle that includes the Pod 3 Cover. This is a limited-time offer. Eight Sleep currently ships within the USA, Canada, the UK, Australia and select countries in the EU.

Watch this episode on YouTube!

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Mattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod Pro

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Nov 15, 2022
Sleep Breakthroughs, Stacks & Solutions – Matt Gallant : 996
01:08:50

BiOptimizers sponsored this podcast.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you're going to get into bed with the topic of sleep. Pretty much everyone’s favorite. 

In this conversation, veteran biohacker and BiOptimers co-founder Matt Gallant returns to the show with some straight talk about how to get more and better sleep. He’s spent the big bucks—about $50K he estimates—exploring, experimenting and upgrading his own sleep. He's sharing what he now knows so you can create a sleep stack that supercharges your own energy.

You’ll learn about the most common sleep disruptors and what to do about them. You’ll also learn to recognize sleep stages and how to improve your sleep pathways.

This fun show uncovers the practical sleep devices, wearables, supplements and lifestyle hacks that will lull you to sleep. So many times, you’re tired and you know you want to go to sleep—and yet—your body and mind just don’t connect. The new Sleep Breakthrough makes that connection for you. And when cortisol runs amok and falsely perks you up with a second wind, you’ll know what to do. 

More and better sleep means you’ll be a higher-performing human. So, get some tonight!

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://sleepbreakthrough.com/dave and use code DAVE10 to get an extra 10% off

Watch this episode on YouTube!

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! 

Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Black Friday 25% off sale plus get two FREE organic pillows ($330 value) with mattress purchase. Through Nov. 27, 2022, only. 

Cooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System

Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount

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Nov 11, 2022
Skincare Hacks With Meteoric Results – Andy Hnilo : 995
00:49:49

Alitura Naturals sponsored this podcast.

IN THIS EPISODE OF THE HUMAN UPGRADE™…… you’ll learn about skincare ingredients that can either nourish or harm your skin. You’ll find out about standards in skin care products, what “clean beauty” means, and what to look for on product labels.

Andy Hnilo, founder of Alitura Naturals, joins the show to talk about skin fitness from the inside out and why using skincare products with ingredients found in nature is the way to go. That means things like pearls, meteorites, clay, CoQ10, enzymes and more.

This conversation gets into ways you can get better skin by:

  • choosing the right nutrient-rich specialty products you can apply topically; 
  • pairing natural skin products with other biohacks, like red light;
  • making nutrition and fitness upgrades; and
  • exploring supplements, peptides and other wellness options.


Improving skin health also means avoiding fillers and chemicals. Toxins both in skin care products and the environment tremendously impact your skin. Acne no longer drives only teenage angst. Adult acne continues to rise, with women affected more than men. Acne affects more than 50% of women between the ages of 20 and 29 and more than 25% of women between the ages of 40 and 49. (American Academy of Dermatology 2012.) 

Andy himself struggled with acne—so he knows the toll it takes from outside appearance to inner emotional roil. So, he searched for answers: “It was the products that I was using and then also what I was ingesting,” Andy says. “What I was putting into and onto my body.”

This get-smart guide to product ingredients, environmental awareness and lifestyle tips can help you find your own skin solutions. 

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://alitura.com and use code humanupgrade to save 20% sitewide.

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! 

Upgrade Your Air Quality: https://hypoair.com/Dave/

Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewide

Kickstart Autophagy: https://timelinenutrition.com/DAVE, use code ASPREY10 to get 10% off any plan

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Nov 09, 2022
Upgrade Spotlight: Calm the Chaos, Then Drink the Water – Analemma : 994
00:42:45

Analemma sponsored this episode.

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. 

Introducing Analemma! During this Upgrade Spotlight with Mario Brainovic, CEO of Analemma, you’re going to find out about a tool that transforms regular water into a supercharged, full-spectrum, coherent state. The kind of water you drink absolutely influences the quality of your life. You’ll learn the science behind Analemma and what it can do for your health and energy.

Why water? You think you know the basics: stay hydrated daily, avoid plastic bottles and use a filtration system at home. Well, Analemma says water goes way beyond the basics—all the way down to your cellular level. You’re 70% water in body mass, but 99% water on a molecular level. You’re basically very clever water. 

The Analemma device—similar in looks and function to a magic wand—radically changes the state of drinking water. Environmental forces cause H2O molecules in drinking water to behave chaotically. At an atomic level, water molecules crash into each other constantly. Your body’s susceptible to that influence.

“We found a way to bring order to this chaos,” Mario says. “When you swirl an Analemma through the water, what happens is that those same H2O molecules start forming a liquid crystalline structure. They start behaving harmonically. They, colloquially speaking, join hands.”

Analemma water is not exclusion zone water. It's something different. “It also is structured water, but we came to it in a very different way,” Mario says. “The key element to it is its stability.”

This conversation gets right into the science of Analemma and several studies. You’ll find out how:

  • a new study is measuring the rise in ATP levels (in mitochondrial energy) when people drink this water.
  • this water affects the human microbiome 
  • this water reduces your biological age by one to 12 years by regenerating your cellular system, according to GlycanAge.
  • you get an instant balancing effect between the left and the right brain hemisphere
  • how a cooling affect happens on your brainwaves almost instantly when drinking this water
  • this water restores the biodiversity of infertile soil


SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://analemma-water.com and use code dave10 to save 10%.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Nov 05, 2022
Sauna Big Wins: Body Detox & Depression Relief – Connie Zack : 993
00:55:00

IN THIS EPISODE OF THE HUMAN UPGRADE™… You’ll learn about the ways using a sauna can charge your energy, help you heal physical and mental health conditions—and science that backs that up. 

Sunlighten sponsored this episode.

Connie Zack joins the show to talk about the far-reaching benefits of sauna use and what’s new in the field of infrared light. For more than 22 years, Connie and her husband, Aaron, have introduced infrared light therapy to 13 countries through Sunlighten. They’re leading innovations in infrared light therapy and infrared sauna manufacturing. 

This conversation covers a range of good things you’ll experience from using a sauna:

  • how infrared light affects the body and triggers a biochemical cascade of benefits;
  • how near infrared penetrates the body to interact with mitochondria;
  • why the real magic of infrared combines both light and heat;
  • what evidence connects infrared and detoxification—and why sweating wins;
  • why you sleep better—without feeling exhausted—when you do a sauna session before bed;
  • how infrared shows promising relief for those who experience depression; and 
  • practical ways to incorporate sauna into your own stack for better sleep and higher performance.


Big takeaways for you:

  • Sauna for Detox: Results from a blood-urine-sweat study support infrared for detoxification, and it’s more than just thermoregulation as traditional medicine often argues.
  • Sauna for Depression: Chronic inflammation is associated with depression and may be a protective, inflammatory response involving thermoregulatory pathways, the immune system, serotonin system, heat shock proteins and more. Studies show that raising core body temperature can improve major symptoms of depression


Connie’s been on the show before, so check out Saunas Use Infrared to Power Detox, Immunity & Renewal – #823 to find out how infrared sauna helps you with immunity and recovery.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.sunlighten.com/dave to save up to $600 on your sauna purchase.

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! 

Brain Training with Sound & Vibration: https://specials.braintap.com/dave to get 30% off

A Cleaner Nicotine Alternativehttps://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozenges

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Nov 03, 2022
Authentic Networking: The Give & Get Starts with Real Relationships – Joe Polish : 992
00:57:34

IN THIS EPISODE OF THE HUMAN UPGRADE™…Joe Polish, considered “the most connected person on the planet,” shares networking strategies that help you get what you want by giving people what they want.

Dave Asprey recently connected with Joe in person to talk about Joe’s new book so you can use nine genius principles to turn your business—and your personal relationships—around. 

If you’re not asking “what’s in it for them?” when it comes to the people in your life—clients, colleagues, family and friends—you’re missing some important opportunities. Here are a few things you’ll learn from Joe’s new book, “What's in It for Them?: 9 Genius Networking Principles to Get What You Want by Helping Others Get What They Want,” as a how-to guide:

  • Deepen rapport and connect with others by identifying and reducing their suffering
  • Update Dale Carnegie’s insights to win the right friends and influence the right people
  • Overcome others’ intimidation tactics to find true appreciation in relationships
  • Build character for better results than capabilities can ever give on their own
  • Use basic marketing principles to find true love
  • Protect your efforts from the “takers” of the world


Joe did the hard work to heal from trauma and overcome addiction. He then spent years developing a genuine and generous approach to networking and building rapport. This approach propelled his business and led him to develop the Genius Network, one of the world’s most impactful networking groups for high-achieving entrepreneurs.

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! 

Harness Cold to Improve Health & Performance: https://www.cryobuilt.com

Customized Nootropics for Your Own Neurochemistry: https://nootopia.com/dave, use code DAVE10 to get 10% off. Learn more on The Human Upgrade podcast: Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant – #861

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Nov 02, 2022
Mini-Episode: Cool Facts Friday #28
00:07:22

In this Episode of The Human Upgrade™...​

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

• How (and why) brain cells transfer mitochondria to one another

• How a newly discovered molecule stimulates hair growth

• How a tired brain drives poor decision-making

EPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms.https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.

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Oct 28, 2022
Finding Your True North Through Yoga – Baron Baptiste : 991
01:06:06

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how a yoga practice can be a vehicle for inner transformation. This conversation looks past the popularity of yoga as a fitness trend and into its deeper potential for human development. You’ll also learn how yoga can be a way for you to explore your whole being—from physicality to emotions to thinking.

“A yoga practice often can be the missing ingredient for people,” says renowned yoga master Baron Baptiste. “Often I hear, ‘I added yoga practice to my routine and regimen, and it just shifted everything for me.’ It's a very different way of working your body, mind and breath integration.”

Baron devotes his own life to the study and practices of human development. For more than 30 years, he’s facilitated education through yoga principles and teachings.

His power vinyasa yoga— The Baptiste Methodology—includes the physical (asana), meditation (dhyana) and inquiry (niyama). 

“Iyengar was one of my primary teachers,” Baron says. “One thing I borrowed from him is the rigor to a body alignment—a True North Alignment.”

Baptiste Yoga is a systematic approach made up of 53 poses, or asanas, that are linked together by connective momentum and consist of five classical pillars: Drishti (gaze), ujjayi (breath), bandhas (foundation), tapas (heat) and vinyasa (flow).

More about Baron Baptiste: Baron began to seriously study yoga at age 12. As the son of two of America's yoga pioneers, he’s got a great life story that highlights the transformative power of yoga. He trained extensively in all the major traditions before beginning to teach yoga in Los Angeles in the late 80s and creating Baptiste Power Vinyasa Yoga in the mid-90s. He’s worked with celebrities, Olympians and professional athletes. He founded the Baptiste Power Yoga Institute that reaches people around the world. Baron’s also a New York Times bestselling author of multiple books, Emmy-award film maker and public speaker.

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Oct 27, 2022
What Happens When You Die? On Death, Angels & Psychic Powers – Julie Ryan : 990
01:09:08

IN THIS EPISODE OF THE HUMAN UPGRADE™… biohacking goes in a different direction. This frank discussion looks at the dying process and how people and those close to them (family and friends) experience death. You’ll learn about the existence of angels and the power of psychic abilities—even if you may be a skeptic. The conversation also explains what a “medical intuitive” does and how a medical intuitive facilitates energetic healings.

Cool show today! And not what you might expect.

Avid biohacker Julie Ryan checks a lot of success boxes: businesswoman, serial entrepreneur, author, radio show host and podcaster. She also invents surgical devices that sell globally; some have been on the market for three decades. She’s founded nine companies in five different industries. 

She checks a lot of unconventional boxes, too. She’s a psychic and medical intuitive. This means she can sense medical conditions and illnesses in people—like a human MRI machine. Then she facilitates energetic healings and says she does a lot of work with stem cell energy.

Julie scans animals, accesses people’s past lives and senses how close to death someone is. She communicates with spirits both alive and dead. Even cooler—Julie’s psychic and medical intuitive skills are learned and she teaches those skills to others.

Julie talks about the “glorious” side of dying, a process that she says involves angels, multitudes of deceased family and friends, the spirits of deceased pets, and countless serendipitous (and miraculous) moments that are all part of a prescribed series of events. She calls this the “12 Phases of Transition™” and broadly outlines this in today’s episode.

SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS: Julie’s giving a digital or audio copy of her books to every listener who wants one. Go to https://askjulieryan.com/ask-julie/. Mention you heard Julie on this podcast and would like a copy.

  • “Angelic Attendants: What Really Happens As We Transition From This Life Into The Next” or “Angel Messages For Kids” or “Angel Messages For Dogs” or “Angel Messages For Cats”


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Oct 25, 2022
Do You Have Cancer? A New Whole-Body MRI Scan Sees Everything – Dr. Raj Attariwala : 989
01:02:04

Prenuvo sponsored this episode.

IN THIS EPISODE OF THE HUMAN UPGRADE™... you’ll find out about a new healthcare model that’s putting you fully in control of your health with whole-body MRI scans. 

Dr. Raj Attariwala, Prenuvo’s founding radiologist, joins the show to explain how Prenuvo gives you early insight into what’s going on under your skin. His Ph.D. in Biomedical Engineering and medical degree in Nuclear Medicine and Radiology informed how he created Prenuvo’s whole-body MRI device software. Here’s what Prenuvo’s scans can do:

  • detect nine of the 10 top cancers in stage one 
  • detect nearly 500 other medical conditions 
  • look at degeneration of the spine and body composition
  • look at the blood in the brain and the blood vessels in the center of the brain


Dave visited Prenuvo’s new Los Angeles facility right before the start of the 8th Annual Biohacking Conference in Beverly Hills to talk with Dr. Raj about Prenuvo’s innovative take on the MRI scan. With AI, Prenuvo’s bringing in quantitative reproducibility, which means you can start to see subtle changes throughout your body over time.

In this conversation, you’ll learn

  • Why it’s so important to know your health baseline instead of waiting for symptoms to present and disease to progress. The reactive medical system in the U.S. focuses on disease management after it occurs. 
  • What types of medical issues show up that may be overlooked or dismissed by your primary care doctor or other medical professionals. Existing annual checkups are relatively useless.
  • How Prenuvo’s whole-body MRI scans can give you an “age score” for your physiology that you can track over time. This means you can make proactive, informed decisions about your own health.


SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get a $300 discount off Prenuvo’s Whole Body Scan ($2,199 instead of $2,499). You’ll get your scan images and radiologic analysis via your smartphone app or the web. Book online: https://prenuvo.com/DAVE or book via phone: 1-833-PRE-NUVO (1-833-773-6886); mention code “DAVE." This discount is valid through March 10, 2023, in all Prenuvo clinics throughout the U.S. and Canada.

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Oct 21, 2022
Menopause Bootcamp: Ditch the BS and Get to Solutions – Dr. Suzanne Gilberg-Lenz : 988
01:05:34

IN THIS EPISODE OF THE HUMAN UPGRADE™… menopause and the perimenopausal years leading up to it take the spotlight as a topic frequently requested by listeners. Great timing! It’s World Menopause Awareness Day Oct. 18 and World Menopause Awareness Month in October.

More than 1 million women in the United States experience menopause each year. Still, little is known, researched or taught in medical schools about the health effects of this natural biological occurrence.

Guys who love the women in their lives and younger women will get a lot of benefit out of the show, too, and come away armed with information. Note that some women go through menopause at ages earlier than 40 for various medical reasons and will want to keep listening.

“I want people to stop being afraid to say menopause,” says Dr. Suzanne Gilberg-Lenz. “I think there's a lot to be said for just saying the word out loud. If we can deweaponize the term and just be talking about it like we would any other life phase, then we can be there for each other and we can also learn from each other.”

Dr. Suzanne, an OBGYN board certified in integrative and holistic medicine, brings her expertise to the show to tackle this complex topic. Her “endless curiosity about the human experience” propelled her to uncover ways to ease women through menopause stages with effective tools. She looks at the science and also brings in holistic elements, including Ayurveda.  For more than two decades, she’s led women through life transitions. 

Her new book “Menopause Bootcamp: Optimize Your Health, Empower Your Self and Flourish as You Age” offers practical steps and solutions that can help women navigate the many menopausal changes they may experience. Some of what you’ll learn in this extensive conversation:

  • Ways to de-pathologize menopause—which contributes to healing ageism.
  • What’s actually going on with your hormones during the transition to menopause and beyond.
  • Why hormone testing isn’t all that useful.
  • Why Menopausal Hormone Therapy (MHT and what used to be called hormone replacement therapy, or HRT)—continues to be misunderstood and controversial.
  • How to craft specific questions to better advocate for yourself with doctors.
  • How to recognize symptoms that can range from moderate to severe to even debilitating.
  • How to manage symptoms that disrupt the activities of daily living and long-term health.
  • How physical changes can drive mental health issues during this time of your life.
  • How to take control of your symptoms and find real solutions.


Dr. Suzanne’s “Menopause Bootcamp” touches on prejudice in medicine and how to break free from the societal bullshit surrounding menopause so you can get appropriate help and treatments.

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Oct 19, 2022
Kava: Nature’s Stress-Relieving Nootropic – Cameron George : 987
00:48:03

IN THIS EPISODE OF THE HUMAN UPGRADE... kava expert and founder of TRU KAVA, Cameron George, joins the show to share new information about the many body/mind benefits you can get from kava.

TRU KAVA sets the industry standard for kava quality, safety and education. On episodes #731 and #859, we talked about kava’s historical origins and uses, how it can be safely consumed, and how it’s extracted and processed today.

You can use kava for both energy and sleep. It’s also a natural alternative to recreational alcohol and drug use. “It's like a calm, enhanced state of natural sobriety,” Cameron says.

If you struggle with social anxiety, kava’s roots in community and social connection can improve your relationships, too.

Today’s conversation further expands the kava discussion.

“Kava is a stress-relieving nootropic,” Cameron says. “It's a natural elixir that's prepared from the roots of a plant that grows in the South Pacific. Indigenous people have used it for thousands of years and prepared this food-grade drink kind of like coffee. On the stress-relieving side, on the nootropic side, they've prepared it and used it in almost every context imaginable, weddings, funerals, spiritual ceremonies, social gatherings. It helps to open up the opportunity for human connection, but it also helps to get people focused yet relaxed and calm and in a very safe space neurologically.”

Kava studies show promise for people who may be experiencing mental health issues. You’ll learn about kava’s potential to transform mental health care and its therapeutic applications for mental/trauma-related illnesses. Kava works on a psychological, emotional and physiologic level.

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Oct 14, 2022
Finding Modern Medicines in the Botanical World – Cassandra Quave, Ph.D. : 986
00:48:43

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how botanical remedies treat infectious and inflammatory diseases. You’ll get a fascinating look at how plants and microbes interact and how antibiotic resistance evolves. And you’ll meet a leader in the field of medical botany who travels to remote locations and communities around the globe seeking out modern medicines from plants. 

  • Medicinal plants make up the primary form of medicine for 70–95 percent of people living in most developing countries. 
  • At least 4 billion people are dependent on plants for medicine.


Ethnobotanist Cassandra Quave, Ph.D., is an herbarium curator and associate professor of dermatology and human health at Emory University. (She’s also a writer, speaker and podcast creator/host.) She teaches courses on medicinal plants, food, and health and her Quave Research Group leads anti-infective drug discovery research initiatives. 

Dr. Quave’s also the co-founder and CEO/CSO of PhytoTEK LLC. This drug-discovery company works to develop solutions from botanicals. In particular, they look at treatments of antibiotic-resistant infections like MRSA.

Her battle with MRSA is personal. She was born with congenital skeletal deformities and had her leg amputated at age 3. She nearly died from a staph infection that infection required more amputation. Her early life and disability experiences shaped her life’s work with medicinal plants.

She chronicles her extraordinary life, field work and scientific discovery in her book, “The Plant Hunter: A Scientist’s Quest for Nature’s Next Medicines.” 

Plants are incredibly complex, and science has barely scratched the surface, Cassandra says. “Some of our best drugs for infection, cancer and pain were originally found in plants,” she says in her book. “Even though they may be produced in a factory setting now, the original chemical blueprints came from plants.”

Cassandra studied pre-med in college with a double major in biology and anthropology. She couldn’t find a connection between the two fields until she journeyed to the Amazon where she studied with a local shaman/healer who relied on plants as medicine. She realized instead of going into the practice of medicine, her true path was the discovery of new medicines from nature.

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Oct 11, 2022
Upgrade Spotlight: How to Use Your Breath to Stop Stress – Othership : 985
00:29:23

Othership sponsored this episode.

 IN THIS EPISODE OF THE HUMAN UPGRADE™…you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. 

Introducing Othership! During this Upgrade Spotlight, you’ll find out how Othership’s breathwork app teaches you ways to manage your most prevalent stressors. Things like tension, anxiety, overwhelm, processing emotions, irritability, trouble sleeping, low energy, nervous system dysregulation or mental health issues. 

When you begin to regularly incorporate breathwork into your life, you notice and feel the emotional, mental and physical differences right away. Breathwork is a visceral, physiological shift that you can reach in under five minutes. It’s the perfect primer to bring you into a meditative state, with even more physical benefits. 

BONUS! You can experience this shift by following along with the live demo in this episode led by Othership co-founder, Robbie Bent. (Make sure you’re not driving!)

Robbie joins the show to talk about the power of adding a breathwork practice to your everyday routine. If you’ve tried meditation and it wasn’t your thing, or you struggle with consistent mindfulness, the Othership app gives you lots of options to find what fits.

You can access more than 500 guided breathwork sessions within three styles: up, down and explorer. Othership combines breathing techniques and guided meditations created by psychotherapists, wellness practitioners, hypnotherapists, artists and DJ’s, spiritual teachers and life coaches. The sessions are music-driven, science-backed and curated by expert facilitators. 

The Othership app helps you build and sustain a new mindfulness routine – all through the power of your breath. Whether you have time to practice for one minute, or 60, you’ll be able to shift your state in a session style that works best for you, such as:

  • Deep breathing + breathwork
  • Guided meditation
  • Affirmations + visualizations 
  • Sound healing
  • Hypnosis
  • Somatic release therapy
  • Vocal toning
  • Intention setting
  • Self-massage + stretching
  • Movement + dance
  • Mind-body connection
  • Mindful walking + working

 

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Oct 08, 2022
How Brain Training Changes Your Frequency – Dr. Patrick Porter : 984
00:53:43

(BrainTap® sponsored this episode.)

IN THIS EPISODE OF THE HUMAN UPGRADE™… brain expert Patrick Porter, Ph.D., joins Dave at the 8th Annual Biohacking Conference in Beverly Hills to talk about training your brain. Dr. Porter pioneered the use of brainwave entrainment with a technology-enhanced meditation device called BrainTap.

Whether you’re a newbie, a hard-core devotee or somewhere in the middle of your biohacking journey, you already focus on body exercise and nutrition. You probably manage your stress and mental health, too. It’s all training of some sort, which is where BrainTap comes in. It’s a specific kind of training for your brain.

New discoveries in science reveal that you can form new neurons in your brain, called neurogenesis. Your brain state isn’t fixed! And then there’s neuroplasticity, a process of adaptive structural and functional changes to the brain that involves connections to your nervous system.

BrainTap’s unique technology uses light, sound and vibration to train and regulate your brain for relaxation, sleep, performance, weight loss, aging and more. To get to a higher personal frequency on the regular, you want to achieve coherence.

Since Dr. Porter specializes in the science of calming the brain, you’ll find out how you can manage your physiological and mental health in today’s super stressed-out world. You’ll also learn how impact remote work, remote learning and pandemic isolation impacted brain health and memory.

This conversation gets into some of BrainTap’s exciting research with aging populations and elite athletes. too.

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Oct 07, 2022
How to Eat Smarter and Trigger Your Metabolic Switches – Shawn Stevenson : 983
00:54:53

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how you can make smarter food choices to support your metabolic energy and upgrade your brain. You’ll also find out some new things about body fat. For example, did you know that it’s a complex organ that communicates throughout your entire body system? You’ll get tips on fat loss essentials and how to use them to your advantage. 

Today’s guest, Shawn Stevenson, hosts a popular podcast called The Model Health Show. He’s a nutritionist, researcher and bestselling author with education and experience in business, biology, and nutritional science.

Shawn’s been in the health and wellness space and doing clinical work as a nutritionist for nearly two decades. He’s known for his ability to keep learning and evolving his approach with deep research into the science of human health.

He’s all about improving human performance and energy with science-backed basics like food in his “Eat Smarter” book and sleep in his “Sleep Smarter“ book. 

This episode gets right into food choices you can make—and why they work—to stoke your metabolic energy. Topics like:

  • How people can better understand the process of fat loss.
  • How the misconstrued science of calories contributes to how much people struggle with their diets.
  • What metabolic switches are, what do they do, and why it’s important for you to know how to turn them on and off.


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Oct 04, 2022
Mini-Episode: Cool Facts Friday #27
00:10:31

In this Episode of The Human Upgrade™...​

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

• Saving your poop may save your microbiome

• Insults trigger a mini slap in the face

• Young cerebral spinal fluid supports memory in aging brains

• The distinct role your nose plays in your friendships


EPISODE SPONSOR: Get Fit in Five Minutes: Go to https://www.carolbike.com. Use code HumanUpgrade to get 2 years of free membership (a total savings of $360). CAROL Bike also offers a 100-day home trial of the CAROL Bike 2.0. Learn more: How to Hack Your Cardio Workout – Ulrich Dempfle– #978.

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Sep 30, 2022
How Butyrate Supports Gut, Cell & Brain Function – Jessica Kane Berman : 982
00:45:34

BodyBio sponsored this podcast.

 IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn how butyrate and phospholipids keep your gut, cells and brain performing at their best. You’ll find out how your mucosal barrier defends against pathogens in your gut microbiome. You’ll also learn about discoveries in the field of cell membrane medicine. This focus determines how your body functions now and also how you age.

Jessica Kane Berman joins the show to share new information and interesting science about cellular health from the perspective of BodyBio, the company founded by her grandfather, Ed Kane, an inventor, health explorer and early biohacker. He went looking for answers to his own health issues in the 1980s and got deep into the science of fatty acid research and cell membrane medicine through blood testing.

BodyBio sticks to a very specific group of products, most notably butyrate and a phospholipid complex of phosphatidylcholine. Jess explains how true liposomal phosphatidylcholine and phospholipids get through to the cells to help rebuild that membrane. 

Here’s a few good things butyrate does in your gut:

  • Helps maintain the thickness of the mucosal barrier—keeps the good in and the bad out
  • Helps the expression of tight junctions and strengthens the gut wall
  • Expresses MUC2: this produces mucus, which thickens your mucous lining
  • Regulates T-Cells and helps lower cytokine release
  • Increases microbiome diversity
  • Anti-inflammatory properties help improve intestinal barrier function and mucosal immunity

Butyrate goes way beyond the gut to influence bone mass and density, asthma and allergies, histamine intolerance, body detoxification, inflammatory brain pathways, and mitochondrial function. Butyrate also can alter gene expression, protect against cancer, and regulate the body’s immune system.

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Sep 29, 2022
Hacking Brain Fog – Interventions With Dave – Keri Glassman, MS, RD, CDN : 981
00:19:44

In this Episode of The Human Upgrade™...​ Dave talks about what could be causing brain fog with a podcast guest in this impromptu intervention. Keri Glassman, MS, RD, CDN, recently spoke about gut health as the expert for Omni-Biotic probiotics. During the interview, she was searching for a word and got frustrated she couldn’t grasp it quickly. This intervention looks at the potential culprits responsible for Keri’s brain fog and memory hiccups: 

  • Thyroid
  • Hormones, such as testosterone and DHEA
  • Perimenopause
  • Mast cell-mediated inflammation
  • Cortisol & stress
  • ADHD
  • Mold toxins
  • Mercury & lead


Keri is a registered dietitian, certified nutritionist, healthy cooking expert and author of four books. She also founded Nutritious Life, a lifestyle and media company and Nutritious Life Studio, an online education platform focused on nutrition, coaching, and business.

Find tips and resources on the episode webpage.

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

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Sep 27, 2022
The Science of Changing Your Mind – Legacy Upgrade ft. Dr. Joe Dispenza : 980
00:59:56

IN THIS EPISODE OF THE HUMAN UPGRADE™…a legacy upgrade conversation with Dr. Joe Dispenza explores how you can change from the inside out through a combination of neuroscience, epigenetics, quantum physics—and even a divine source. “I teach people the science of changing their mind and what it is to truly transform,” he says.

He shows people how to rewire their brains and recondition their bodies to make lasting changes by way of science, energy and mysticism. His background and expertise include training in neuroscience, neurology, cellular biology, brain function and chemistry, memory formation, and aging and longevity.

From healing illness to evolving consciousness, Dr. Dispenza examines how to connect with the divine and bridges the mystical with science. “It's really important to have science demystify that process,” he says. Why? Because science is a contemporary language that offers you explanations, helps you understand the how and why, and assigns clear meaning. 

“Here's what I know,” Dr. Dispenza says. “We have evidence that you can make your brain work better. As you can prove also, we have evidence that you can make your heart work better. We have evidence, you can strengthen your immune system. We have evidence, you can change your gene expression in four days. We have evidence, you can lengthen your life from meditation, just by lengthening your telomeres and changing your state. We have evidence in the scientific world that people actually can transform.”

Listen on to learn about the power of inner work, elevated emotions and human connection.

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Sep 22, 2022
Meditation Hacks Get You Into A Peak State in Less Time – Vishen Lakhiani : 979
00:57:04

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about a “6 Phase Meditation” approach that absolutely everyone can do—and benefit from!—no exceptions. This custom-designed meditation sequence gets you into a peak state in just a few minutes. No boredom, special breathing, or clearing your mind required. You’ll find out how to make meditation work for you and how you can use intuition as one of your greatest strengths.

Episode guest Vishen Lakhiani took up meditation at age 26 as a way to cope with the stress of working for a startup in Silicon Valley. That decision changed his life so dramatically that within two years he quit to pursue meditation, other tools of personal development, and then spread awareness and education to people around the world. He’s taught his signature 6-phase meditation style to world-class athletes, professional entertainers and high-performers in all types of business. He also founded Mindvalley, an international learning platform.

Vishen’s newest book, “THE 6 PHASE MEDITATION METHOD: The Proven Technique to Supercharge Your Mind, Manifest Your Goals and Make Magic in Minutes a Day,” outlines a series of science-backed mental exercises for accomplishing your goals. It condenses the wisdom of nearly 1,000 neuroscientists, monks, yogis, and meditation experts into a hyper-efficient programming script that you can run through your mind any time of day.

Unlike traditional meditation that encourages a calm and serene environment, the 6 Phase Meditation Method can be done from anywhere—your bed, your office or even on your next flight. “It's six different practices that you layer on that put you in a hyper-optimized state,” Vishen says. 

You’ll get a lot out of this fascinating conversation that gets into realms of spirituality, psilocybin, perceptual diversity, physics, brain waves, and altered states. 

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSMindvalley.com/books/6phase

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Sep 20, 2022
How to Hack Your Cardio Workout – Ulrich Dempfle : 978
00:44:08

CAROL Bike sponsored this podcast. 

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll learn about new research that’s pinpointing the most effective cardio workouts. You’ll find out that you can do a cardio workout in just 15 minutes a week and still increase your cardiovascular fitness. You’ll also get an introduction to the new CAROL Bike 2.0 and its upgraded great features.

Ulrich Dempfle, MBA, Chief Product Officer, CEO and co-founder of CAROL Bike, returns to the podcast with exciting new research results. CAROL’s REHIT (Reduced Exertion HIIT) workout retained all its effectiveness yet cut its time nearly in half—from 8 minutes and 40 seconds to five minutes.

CAROL Bike continues to innovate fitness and prove that more or longer sprints aren’t better. “What matters is that you sprint at your personalized maximum intensity, switching from zero to max in a fraction of a second,” Ulrich explains.  An investment of only 5 minutes, 3 times a week means you can reap powerful cardiovascular benefits, even gain strength, and get on with your other biohacks.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.carolbike.comUse code HumanUpgrade to get 2 years of free membership (a total savings of $360). CAROL Bike also offers a 100-day home trial of the CAROL Bike 2.0.

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Sep 15, 2022
Don’t Accept Suffering as Normal – Dr. Gabor Maté : 977
00:48:04

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll learn to define what’s really “normal” when it comes to your health. You’ll explore how today’s culture stresses the body, burdens the immune system, and undermines emotional balance. And why Western medicine often fails to treat the whole person.

This conversation covers an investigation into the causes of illness, a critique of how our society breeds disease, and offers a pathway to health and healing. One of the surprising things you’ll learn has to do with authenticity.

“The loss of authenticity is one of the major impacts of trauma,” says renowned Canadian speaker and bestselling author, Dr. Gabor Maté. “It's also a major cause of physical and mental illness.”

Dr. Maté is highly sought after for his expertise on topics like addiction, stress, trauma, and childhood development. He spent two decades in family practice and palliative care. He also worked for over a decade in Vancouver’s Downtown East Side (Canada) with patients challenged by drug addiction and mental illness.

In his newest book, “The Myth of Normal: Trauma, Illness, & Healing in a Toxic Culture,” he pushes back on the prevailing understanding of “normal” because it neglects the roles that trauma and stress—and the pressures of modern-day living—exert on our bodies and our minds at the expense of good health. 

“If you're suffering, don't accept it as normal, but ask what's going on here?” Dr. Maté says. “Let the suffering instruct you that there's something going on; that what you think is normal is actually not healthy or natural for you.”

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Sep 13, 2022
Male Hormones: How Testosterone and Toxins Mess With You – Tracy Gapin, M.D. : 976
00:52:16

IN THIS EPISODE OF THE HUMAN UPGRADE... you’ll learn that while yes, testosterone fuels energy and performance, it’s not the be-all and end-all solution for men’s health woes. A systems biology approach considers many other aspects and provides a broader perspective about what’s going on with you.

This conversation features board-certified urologist Tracy Gapin, M.D., one of the 8th Annual Biohacking Conference keynote speakers. He’ll be on the main stage in Beverly Hills in September. He joins this special preview episode to discuss new ways for men to improve their health and performance. He uses epigenetic coaching, hormones, peptide therapy, biometric monitoring, and unique nutrition and lifestyle interventions.

“Testosterone levels over the last 30 years are down by about 30 percent,” Dr. Tracy says. “Free testosterone, which is the bioavailable, active hormone testosterone is actually down over 45%. This is really important. We're not just talking about sex and muscle, we're talking about a man's life and cardiovascular health and cognitive function. The culprit can be debated, but without question, one of the biggest ones in my mind is endocrine disruptors. Toxins, chemicals in our environment that are clearly crushing men's health, clearly crushing testosterone. It's the food we eat, it's the water we drink, it's the personal care products. It's ubiquitous, it's almost everywhere and it's getting worse.”

In his book, “Male 2.0™: Cracking the Code to Limitless Health and Vitality,” he says medical school, residency training and even a two-decade career in urology and surgery specialties didn’t teach him how to get to root causes of men’s issues and solve them. He had a health crash of his own at 42. Since neither he nor his doctor had good answers, he went on a quest of discovery and change. 

He founded the Gapin Institute for High Performance Medicine and created the proprietary N1 Performance Health Program to go beyond conventional options.

This conversation goes even further into what creates epigenetic signals that affect the function and expression of your genes. You’ll learn, too, that your mindset, stress and environment—and how you do or don’t control those things—have everything to do with your energy and focus. If you’re aiming for higher performance, Dr. Tracy suggests a trifecta that makes sleep a priority, builds resilience to stress, and creates consistent behaviors with intention.

More about Dr. Tracy Gapin: He’s a member of the American Academy of Anti-Aging, the Age Management Medical Group, and the International Peptide Society. He spent almost 20 years at a urology practice in Sarasota, Fla., where he specialized in robotic surgery, minimally invasive treatment for prostate cancer, and men’s health.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS:  TEXT “HEALTH” to 2 6 7 8 6 to get three bonus gifts.

***

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Sep 08, 2022
Female Hormones: What Disrupts, Detoxes & Balances Them – Anna Cabeca, D.O. : 975
00:56:38

IN THIS EPISODE OF THE HUMAN UPGRADE... you’ll learn about female hormones: what they are, what they do and what disrupts them. You’ll learn about the hormonal shifts that happen at different ages and life stages and get tips on how to balance hormones and make them work for you, not against you.

This conversation features Anna Cabeca, D.O., one of the 8th Annual Biohacking Conference keynote speakers. She’ll be on the main stage in Beverly Hills in September. Dr. Anna is a Doctor of Osteopathy who’s triple-board certified in gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine. She has additional certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy. 

She joins this special preview episode to talk about female hormones. It’s her particular area of expertise and one of The Human Upgrade’s all-time Top 10 podcast topics. Today’s hormone discussion includes:

  • How hormone disruptors go beyond stress to mold, and product and environmental toxins
  • How estrogen levels change over time
  • What’s going on with progesterone, pregnenolone and DHEA, too
  • What happens to hormones during perimenopause and menopause
  • What’s causing brain fog
  • What to know about bioidentical hormones
  • How detoxing affects hormones
  • How to keep your vaginal microbiome balanced
  • How “food as medicine” helps balance hormones
  • How hormones influence longevity
  • And much more!


For the past 20 years, Dr. Anna's educated and helped women with their hormones through her private practice, books, online videos and articles. Learn more about her work with women’s hormone health:


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Sep 06, 2022
Upgrade Spotlight: Probiotics to Power the Gut-Brain Axis – Omni-Biotic : 974
00:35:56

IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’re listening to a new Upgrade Spotlight episode with Omni-Biotic. You're going to find out how probiotics can do more than keep your gut microbiome in order—specific strains can help you manage your stress and regulate your body’s detox system. 

The beneficial bacteria in your gut support essential processes in the body, such as digestion and absorption, immune function, detoxification, and brain function. But did you know that 80% of the immune system lives in the gut and 95% of serotonin is produced in the gut? That’s a lot for the gut to do! 

Keri Glassman, MS, RD, CDN, joins the show to talk about one of her favorite topics—the gut-brain axis. Keri’s a registered dietitian, certified nutritionist, healthy cooking expert and author of four books. She also founded Nutritious Life, a lifestyle and media company and Nutritious Life Studio, an online education platform focused on nutrition, coaching, and business. 

In this conversation, you’ll learn how Omni-Biotic’s unique delivery mechanism and multi-species, multi-strain formulations work together to upgrade your gut AND your brain. 

The gut-brain access goes two ways, Keri explains. “Your brain is affecting your gut. Your gut is affecting your brain—and from everything. That's why it's so incredibly important to maintain that healthy microbiome and to have a healthy balance of good [bacteria].”

To target the gut-brain axis, Omni-Biotic developed special formulations called psychobiotics: one for detox, the other for stress. Then they put them to the test in clinical studies.

  • Hetox contains eight beneficial bacterial strains. Clinical studies show improvements in liver function, cardiometabolic markers and inflammation markers related to liver health. 
  • Clinical studies show that Stress Release supports digestion and the gut flora during times of stress, reduces intestinal inflammation, increases emotional balance, cognition, and mood. 

 

More to Know About Omni-Biotic Probiotics:

Omni-Biotic also tests its probiotics in an artificial GI simulator against other top probiotic brands in the U.S. market. It ensures that 83% of its probiotics arrive alive and active in the intestines. In comparison, the probiotic survival rate of other brands averages 7%. 

The bacterial strains in Omni-Biotic are freeze-dried to make them more shelf-stable and the powder contains specific prebiotic nutrients. These prebiotic nutrients serve as the food source for the probiotic bacteria. 

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Sep 03, 2022
How to Drop Happily Ever After and Do Relationships Better – John Kim, LMFT : 973
00:44:24

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn how to recognize your own sh*t and be a better partner in relationships. 

Want a sustainable partnership? Communicate and apologize; fight without fighting; identify codependent behavior (your own); and manage jealousy (also your own). 

This conversation gets into how you can let go of unrealistic ideals of how you think love and relationships should be and live fully in the present. You’ll also get tips on how to be emotionally responsible to people you love every day.

Guest John Kim, a licensed marriage and family therapist, as well as a life coach, cracks his life into two big pieces… split on either side of what he calls “the great divide” of his own divorce several years ago. He did the whole “get a tattoo and a Harley” thing to find his way.

He also combined what he learned in therapy school with life coaching and technology to be mobile and create online communities. He became known as an unconventional therapist, seeing clients at coffee shops, on hikes, or in a CrossFit box. He’s built a devoted following of fans who love the frank and authentic insights that he—as “The Angry Therapist”—freely shares on social media. TikTok’s his jam, with over 450K people tuning in for his “shot glass” bits of life wisdom.

In his newest book, written with his romantic partner and fellow therapist Vanessa Bennett,  John takes a different (honest, humorous, raw) approach by dissecting his own relationship dynamic to bring clarity to yours. Each part of “IT’S NOT ME, IT’S YOU: Break the Blame Cycle, Relationship Better” gives you questions to ask yourself and practices to do. It’s a book that pushes you into doing and putting your newfound knowledge to IRL use. 

Here’s a sneak peek at a few of the Love Lessons (In a Shot Glass) you’ll find in “It’s Not Me, It’s You.”

  • Love is not a battlefield. Your head is. 
  • If someone is unsure about you, it’s never worth the investment.
  • Hold love, don’t grab it.
  • Don’t stop believing (be Journey).
  • Love is what teaches us how to live.


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Sep 02, 2022
Hacking Skin & Gut Issues – Interventions With Dave – Nancy Pellegrino : 972
00:29:37

In this Episode of The Human Upgrade™...​

… Dave tackles multiple issues with former Upgrade Collective member Nancy Pellegrino so she can better manage psoriasis, gut health and anxiety.

Nancy’s been biohacking for a few years but can’t seem to land on the right combination. She does the hacks, uses the gadgets and tech, and takes the products and supplements. Instead of feeling better, she’s feeling overwhelmed with information. She talks with Dave to sort it out, focusing on skin and gut health.

Now in her mid-50s, Nancy’s post-menopausal and does bio-identical hormone replacement therapy. She experienced—and beat!—colorectal cancer in 2017. She routinely uses her Sunlighten sauna, an ozone machine and a ChiliSleep cooling mattress pad.

Her busy life as a teacher and mom to three daughters makes it hard for her to meditate and relax. She’s looking to ease some body distress, focus on solutions and find benefit in biohacks that work for her particular symptoms.

  • She hasn’t found a resolution to chronic psoriasis.
  • Despite following the Bulletproof Diet, drinking Bulletproof Coffee and regularly intermittent fasting, she continues to have unexplained digestive issues. 
  • She wakes up in the night with feelings of anxiety.


Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.


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Aug 30, 2022
Mini-Episode: Cool Facts Friday #26
00:10:41

In this Episode of The Human Upgrade™...​

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

• Gut bacteria convert vitamin A to retinoic acid

• Low-carb diets contribute to depression 

• Lifestyle affects cognitive health more than age 

• More bad news about America’s obesity epidemic 

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Aug 26, 2022
Nillion Gives Crypto & Data Security a Human Upgrade – Conrad Whelan : 971
00:47:42

Dave Asprey partners with Nillion as an advisor and investor.

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn about the frontier of web3 and privacy and what happens to your private data (both on blockchains and in general). You’ll also find out how and why the future moves away from transactions (blockchain) and into computations (multi-party computation). 

Think about where you store your identity and your deepest digital secrets. The current solutions aren’t great — in web2, the Big Tech 'old guard' has been quietly storing and monetizing your data for over a decade, and in web3, blockchains aren't designed to handle private data. A new algorithm, Nillion, inspired Conrad Whelan (the Founding Engineer of Uber) to come out of early retirement and do something about this. 

This conversation looks at the data you unassumingly give away freely, and how it’s captured, held and used/computed on without your consent by large companies and other parties. Conrad believes in a future where your sensitive data and digital secrets can be fully controlled by you (and you alone) using web3 technology. This means you’d be the final gatekeeper of your data with the power to authenticate, authorize and use it as you see fit.

Conrad’s building that future as Nillion’s Founding Chief Technology Officer. His background includes electrical and computer engineering. He worked in the fields of computational electromagnetics before joining Uber as Founding Engineer. He’s developed, tested, deployed and architected software projects at all levels of the software stack as both an engineer and an engineering manager.

In 2016, he retired to focus his efforts on philanthropy and personal passion projects while keeping an eye on the tech world. The promise and potential global impact of Nillion enticed him out of retirement and into the company’s CTO role. What Conrad is building at Nillion aims to:

  • render both computational encryption and centralized storage of private data obsolete;
  • fundamentally change the way private data is stored and processed;
  • offer alternative non-blockchain ways of using decentralized nodes;
  • serve as a ‘Meta Layer’ that provides new and additional functionality to existing blockchains; and
  • enable a host of new real-world applications on its native public network (the Nillion Network).


Whatever your level of tech understanding, this discussion offers critical insights about the next big move in decentralized computing and data privacy.

Find more info in the show notes on this episode's webpage: https://daveasprey.com/conrad-whelan-971/

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Aug 25, 2022
How Regenerative Systems Save the Soil, Animals & You – Robby Sansom : 970
00:58:28

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn why regenerative methods for taking care of soil and raising animals provide a solution that creates food sovereignty, improves human health, and helps reverse climate change. 

Previous episodes of this podcast featured regenerative farming and soil conservation topics. Dave Asprey keeps the conversation going because when you know what’s happening and what companies are doing about this problem, you can be informed and take action to support regeneration efforts in your own way.

Robby Sansom, co-founder and CEO of Force of Nature, joins the show to talk about the new developments igniting real change. 

His roots run deep in the natural food community, caring for soil and caring for animals. He spent much of the last decade studying regenerative agriculture at ranches all over the world. Through this education, he helped found the Austin, Texas-based regeneratively sourced meat company, Force of Nature. The company’s building brand new global supply chains of grass-fed and regeneratively managed livestock. Force of Nature works in partnership with land stewards, ranchers and farmers committed to creating a positive return on the planet. 

There’s an undeniable sense of urgency about the state of soil and its ability to provide enough food for a growing population. Over more than a hundred years of conventional farming and ranching depleted land and disrupted natural ecosystems. These harms (have and continue to) adversely affect animal and human health. Force of Nature focuses on repair and regeneration—in their own operations and by educating farmers and ranchers from homesteaders to big corporations.

In spring 2022, Force of Nature hosted a What Good Shall I Do? event about learning and leading with regenerative intent. This educational forum hosted several dozen speakers from soil scientists to leaders in the regenerative movement to individual farmers and ranchers. By providing information, resources and tools, conventional farmers and ranchers can make the switch to regenerative methods. And farmers and ranchers who already use regenerative methods can improve and have even more impact.

You can get involved, too! In this episode, Robby talks about the true cost of meat and gives tips on what to look for in your own local grocery and how you can support regenerative agriculture and ranching in a way that aligns with your own values. Every small step toward change contributes to a larger movement.

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Aug 24, 2022
How Prebiotic Fiber Makes a Gut-Friendly Bread – Uprising Food : 969
00:48:04

Uprising Food sponsored this podcast. Dave Asprey partners with Uprising Food as an advisor and investor.

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn about bread that’s better for your body—and the important role of prebiotics and fiber in that equation. You’ll also find out about the science that supports new ways of creating bread products—what works and why it works. And you’ll get a look further into the food system and how to adopt solutions with real benefits for your energy and lifestyle.

A 5+ year biohacker, intermittent faster, and cyclical keto devotee joins the show to talk about innovations in bread as you know it. William Schumacher, co-founder and CEO of Uprising Food—aka—”The Loafer and Chief”— traded in corporate life as a former Procter and Gamble marketer to sift through the disinformation to de-villainize bread and create products that taste good and work in synergy with your body.

With all the gluten-free and alternative breads out there competing for attention, what made Uprising stand out to Dave Asprey? Simple. Uprising took action to:

  • tackle the foundational things that give people disproportionate bang for their buck when they eat the products day in day out. 
  • figure out what’s NOT in the product. Most products are loaded with things that are doing damage and there’s a big-time cost. 
  • eliminate gluten and other inflammatory ingredients.
  • choose ingredients that would produce a tasty, functional product and work in the gut to enable inside out transformation.
  • partner with artisanal bakers willing to experiment with baking methods and ingredients. The star ingredient? Psyllium. In this conversation, you’ll get all the details on prebiotic fiber and the benefits of activated psyllium, a bio-active polysaccharide.


Research done at Wright State University Microbiome Labcompared Uprising Food bread with traditional bread. Early results show that Uprising’s prebiotic bread makes nice with gut microbiota.

Curious about bread again? Check out the Uprising Food “Toast Cleanse,” affectionately known as “72 hours to digestive deliverance.” This 3-day protocol includes super toast combinations and levels of bread eating designed to overhaul your microbiome. 

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Aug 24, 2022
Ancient Healing Arts for Your Modern Life – Shaman Jorge Hachumak : 968
01:11:48

IN THIS EPISODE OF THE HUMAN UPGRADE... 

… you’ll learn about shamanism, “spiritual minimalism” and how traditional healing arts connect so profoundly to the natural world. This conversation also explores distinct themes of consciousness, the soul, and deep respect for plant medicine and Ayahuasca ceremony. 

The guest, Shaman Jorge Hachumak, is a Peruvian of Spanish descent who’s made a winding journey into shamanism as a healer. After receiving a European education, he became a practitioner of Chinese Qigong in old Lima’s (Peru) China Town. After a successful career in tai chi competition, he worked with elderly patients in hospitals in Northern Peru. 

During this time, he was taken under the wing of native shamans, witches and herbalists who spent years teaching him the ancient healings. He learned ancient Peruvian medicine arts (not from the Incas, but from the North Coast and the Northern jungle of the Amazon).

He now moves seamlessly between perspectives, having one foot firmly in the rational, scientific world and another in the spirit world.

“The ancient healing arts are deep and expansive—you never stop learning, and what you learn in a lifetime will always be a small fraction of what is available to learn,” he says in his new book, “Journeying Through the Invisible: The Craft of Healing With, and Beyond, Sacred Plants, as Told by a Peruvian Medicine Man.” “I want to offer a larger picture of the Medicine Craft and to create appreciation for other important aspects that are endangered or still not well-known.”

This larger picture includes influences from science, history, religion and the natural environment.

Shaman Hachumak looks at consciousness as two states that lead to both deep understanding of the healing arts and deep self-reflection:

  • Suffering Consciousness keeps us stuck in our negative ways
  • Soul Consciousness is awakened during a ceremony or spiritual moment. Your entire being awakens, and you are shown the way to live according to the dictates of your conscience and the teachings of the spirits.


He also uses his knowledge and experience to broaden people’s understanding of Ayahuasca as a powerful plant medicine. He works to protect Ayahuasca and the traditional ceremony from misuse and exploitation. 

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Aug 18, 2022
What Biohacking Borrows from Shamanism – Manvir Singh, Ph.D. : 967
01:06:02

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll find out about the relevance of shamanism in a modern world and why high performers are turning toward shamanic practices to get ahead.

The show’s guest, Manvir Singh, Ph.D., is an anthropologist at the Institute for Advanced Study in Toulouse, France. He studies universal or near-universal cultural practices, including music, shamanism, and witchcraft. For the past seven years, he’s conducted ethnographic fieldwork in Indonesia.

He recently wrote an article in WIRED magazine titled, “The Shamanification of the Tech CEO,” noting some curious parallels.

  • “Silicon Valley austerity continues to grow more extreme. By 2020 intermittent fasting was no longer enough, and dopamine fasting—an abstention not just from food but from any form of stimulation, including music, eye contact, and playing Magic: The Gathering—had taken off. These self-denial fads are often touted as biohacking innovations. Yet as an anthropologist who has studied austerity in some of the most remote regions of the world, I see them as part of a larger pattern: the self-shamanification of tech CEOs.”


  • “Analyzing an old dataset of 43 nonindustrial societies, I found that shamans in 81 percent of the societies observed prohibitions on food, sex, or social contact. Given that these data were collated from reports by travelers and anthropologists, they are probably an underestimate. Silicon Valley deprivation, it turns out, is less a strange, new development and more the most recent manifestation of a ubiquitous shamanic practice.”


This conversation gets into:

  • shamanism in general
  • the cultural significance of shamans
  • how shamanic practices have made their way into modern culture
  • why humans think they need shamans—or similar “magic” or “other” beings 


More about Manvir Singh, Ph.D.:  Manvir earned a Ph.D. in Human Evolutionary Biology at Harvard University and a Sc.B. with Honors in Human Biology: Evolution, Environment, & Ecosystems at Brown University. He’s received multiple awards, honors, grants and fellowships—from Fulbright Scholarship to visiting scholar and research fellow. He’s written more than a dozen peer-reviewed journal articles and more than a dozen articles for general audiences. He gives talks domestically and internationally on the topic of shamans.

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Aug 16, 2022
How To Be Your Future Self Right Now – Benjamin Hardy, Ph.D. : 966
01:07:30

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll find out how your imagined future directs your behavior right now, rather than your past. You’ll learn how to manage threats to your future self, recognize truths about your future self, and how to take steps to be your future self. You’ll also gain strategies you can start using today for creating and becoming exactly who you want to be in the present moment.

Benjamin Hardy, Ph.D., is an organizational psychologist and author of multiple books on how to improve your mindset. He joins the show to explain how you can borrow from your future and actually be that person right now. 

In his newest book, “Be Your Future Self Now: The Science of Intentional Transformation,” he says, “Research now shows that a person’s past does not drive or dictate their actions and behaviors. Rather, we are pulled forward by our future.” 

There’s no looking back, only moving ahead. Most people, out of fear, limit their view of the future to a narrow range. Take a dangerous leap to think more broadly. Take cues from your brain.

“With neuroscience, the brain is essentially considered a prediction machine,” Ben says. “So, what the brain is always doing is predicting what's going to happen, and learning is essentially just updating its sense of predictions. The brain is always anticipating the future.”

Since you’re already thinking about the future, put those thoughts to use in the here and now with 21 actions  (7 threats to, 7 truths about, and 7 steps for being your future self) designed to transform yourself. For example:

  • Offset a THREAT: Urgent battles and small goals keep you stuck. To exit the rat race of day-to-day mindset requires a shift in your focus. 
  • Face a TRUTH: Failing as your future self is better than succeeding as your current self. The more willing you are to invest in momentary loss and pain directed at a goal, the faster you’ll adapt to the level of your future self. 
  • Take a STEP: Schedule your future self. Put the important before the urgent. Once you commit to your Future Self, you’ll be required to be courageous. Choosing freedom over security is an act of courage.


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Aug 12, 2022
Control Your Mindset with 4 Questions – Legacy Upgrade ft. Byron Katie : 965
00:53:21

IN THIS EPISODE OF THE HUMAN UPGRADE...

…a legacy upgrade conversation with Byron Katie will have you digging deep into the work of fine-tuning your mindset. Her keystone practice, The Work, allows you to access the wisdom you already hold inside you. She explains it as a process to “clear the mind.”

You’ll ask yourself four questions and apply them to a specific problem you’re facing. Going through these steps gives you perspective and a new way of thinking about what’s causing you distress. Questioning diminishes the power your thoughts have over you. And THAT leads to true freedom.

Her work contains elements of therapist, a counselor or a religious leader, though she’s technically not any one of these. She’s been described as a spiritual mentor. As the bestselling author of “Loving What Is: Four Questions That Can Change Your Life," followed by "A Mind at Home with Itself: How Asking Four Questions Can Free Your Mind, Open Your Heart, and Turn Your World Around," her inspirational guidance offers people a different way to think their thoughts so they can change their mindsets and, ultimately, their lives.

Her own story of early life success that spiraled into depression, rage, addiction, and self-loathing, sets the foundation for The Work. “The thoughts like, “I’m not good enough. There's something wrong with me," which was true,” Byron explains. “It was my thinking. My thoughts were aimed out at other people. It was their fault. Then when I would say or do something, I would experience the guilt, so I had this vicious circle going of judgment, guilt, judgment, guilt. It was debilitating.”

She had to save herself.  Several weeks into treatment, she woke up one morning to a state of constant joy that has never left her and four questions clearly in her mind that would lead her out of her own darkness. 

She’s never been able to truly explain this epiphany, nor has she evangelized it. She realized that when she believed her stressful thoughts, she suffered, but that when she questioned them, she didn't suffer, and that this is true for every human being. She simply shares The Work with people who want to make profound life changes—and has continued this path for nearly 40 years.

“I have a lot of people across the globe that are saying their lives are shifting so dramatically they're unrecognizable, but I don't call it The Work for nothing,” she says. “It does take stillness. It takes silence, and it takes being courageous enough to look at the thoughts in your head without trying to change them and accept them the way they are.”

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Aug 09, 2022
Upgrade Spotlight: Cook Faster, Easier & Better With Light – Brava : 964
00:35:44

IN THIS EPISODE OF THE HUMAN UPGRADE™...

... you’re going to find out how to cook differently using an innovative kitchen appliance, Brava, that’s got some cool features that will get you excited about making your meals at home—always a good idea!

First—what Brava is not. The Brava countertop cooking oven isn’t a microwave, isn’t a toaster oven, and isn’t a convection oven.

Instead, it’s a device that cooks with light. Six lamps deliver exact, variable, infrared light waves to your food. Brava synchronizes and controls the amount of power each lamp emits. Simultaneously, the lamps instantly reach full power and turn off just as quickly, creating three independent cooking zones inside the chamber. 

The top five benefits of this cooking method include: Searing (great for your grass-fed steaks), precision, versatility, speed and quality. Brava also cooks up to three different ingredients at the same time. You can air fry, dehydrate and cook your favorite white rice in it (Bulletproof Diet approved). It’s user- and kid-friendly, so your whole family can be part of a lifestyle that prioritizes food that nourishes your body and ups your energy.

Brava’s vice president and professional chef, Travis Rea, led the Brava Culinary Team in developing Brava's patented Pure Light Technology (physicists and mathematicians were in on it, too). He’s on the show to explain the technology behind Brava and how cooking with light will change your entire approach to food.

Travis earned a degree in Culinary Arts at the California Culinary Academy. Prior to Brava, he headed the Food Development team at Williams-Sonoma for eight years where he developed nearly 800 private label food products. His experience also includes leadership roles at Revolution Foods and NatureBox. So, he knows the many facets of creating great food.

Brava takes out the guesswork of meal planning by offering over 7,000 fully automated recipe programs. This means you can enjoy cooking more because it takes less of your time.

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: https://www.brava.comuse code DAVE at checkout to get $200 OFF any Brava set through December 31, 2022. 

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Aug 06, 2022
How Whole Body Vibration Hacks Fitness & Fat Loss – Tony Molina : 963
00:54:20

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn how whole body vibration works and the many ways it benefits your physiology. It’s the nexus between energy and life, says Tony Molina, a performance optimization expert.

This biohack helps you burn more calories,” he says. “It helps you increase strength and reaction time. You can improve skin and circulation, bone density, pain relief, hormonal changes, posture and balance. It's also a lifelong health and longevity partner.” 

He’s talking about the Power Plate. He’s a high-altitude and longevity researcher and Senior Research and Development Specialist at the company.

“Whole body vibration runs off Isaac Newton's second law, so force equals mass times acceleration,” he explains. “Where acceleration is what’s being increased versus mass. And generally, we focus on the mass, whether we do any kind of strength training, we focus on holding mass or dealing with the mass or changing the mass. With whole body vibration and Power Plate, you’re focusing on the acceleration or the speed change.”

Other cool things about whole body vibration:

  • You're changing the formula from conscious effort (like conventional exercise) to subconscious (harmonic vibration).
  • You’re experiencing multiplanar movement that creates an unstable environment that’s proprioceptively challenging. (The nervous system doesn't know what to do, which is a good thing.)
  • Your neuromuscular spindle gets stimulated without the need for the brain even to get involved. (Cognitive confidence!) 
  • Your nervous system itself is ramping up safety signals so the brain understands what it needs to do without you consciously having to do anything.
  • Your reflexes improve; your reaction time gets better; your ability to propriocept allows your posture to improve; and you breathe better.


Listen on to find out more about whole-body vibration training, therapy, and how it can make you live longer, whatever your fitness level or ability.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://powerplate.com/dave to get 20% off a Power Plate® MOVE (save $659) AND a FREE Power Plate Pulse Massage Gun (valued at $249.99) 

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Aug 05, 2022
How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962
01:06:48

IN THIS EPISODE OF THE HUMAN UPGRADE...

…you’ll learn about the critical role metabolism plays in your body’s energy and performance. Important new science findings about human metabolic health shows how you can change your metabolism. To help you make these changes, this episode gives you practical tips and tools for measuring your metabolism and ways to manage it effectively.

Guest Michal Mor, Ph.D., co-founded Lumen with her twin sister, Merav Mor, Ph.D., and three long-time entrepreneur friends nearly a decade ago. As Chief of Metabolic Health & Science, Michal’s background includes degree studies in Medical Laboratory Sciences and Physiology with an emphasis on cardiac arrhythmia. 

The Lumen founders set out to close the gap of what existed in the science and something people could actually use to manage their metabolic health.

Both Michal and her twin, Merav, were multiple-year Ironman participants. Athletic performance—and how to improve it—influenced their work with metabolism. Four years of research and development plus more years of validation studies and beta test users went into developing Lumen.  

Lumen is a hand-held device that accurately measures your metabolism through the breath. It uses a CO2 sensor and flow meter to measure the CO2 concentration in your breath, indicating if your body is in carb or fat burn.

“So, this ability to shift between them, it's not only good for athletic performance it's also improving our quality of life,” Michal says. “It enables us to enjoy life to our fullest potential. It's about longevity. It's about being able to achieve our goals, not having those mood swings. This is so much more than improving athletic performance.”

Lumen has accumulated a metabolic measurement database with over 20m measurements. These insights have shown how lifestyle habits affect metabolism and the body more than previously thought possible. Listen on to learn how with just one breath in the morning, you can set your metabolism course for the day and then monitor it throughout the day.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://lumen.me, use code Asprey50 to get $50 off a Lumen device

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Aug 02, 2022
Mini-Episode: Cool Facts Friday #25
00:12:16

In this Episode of The Human Upgrade™...​

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Tattoos can help monitor your blood pressure 
  • Device that protects against head injuries 
  • Upgrading your avocado toast
  • Ways to manage the harmful aging-inflammation duo 
  • Pee recycling does the soil good


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Jul 30, 2022
How to Fix Your Brain When It’s Tired, Wired and Slow – Matt Gallant & Mr. Noots : 961
00:58:21

IN THIS EPISODE OF THE HUMAN UPGRADE...

 … you’ll find out why aging and stress are the major contributors to neurodegenerative diseases in your lifetime, what you can do to stave off the effects, and how you can kickstart your brain into functioning at a way higher level.

You’ll also learn about:

  • BDNF (Brain-Derived Neurotrophic Factor) and ways to increase it
  • Options for how you can support your brain’s neurogenesis
  • How certain mushrooms and collagen can be used to increase your cognitive function—so you can focus, concentrate and be more creative
  • How customized nootropics can help you reach peak mental performance

 

Matt Gallant keeps coming back on the show to introduce innovative supplements that work with your brain and body. We’ve talked about nootropics, psychobiotics, magnesium, enzymes, blood sugar, gut health and more. 

As co-founder of BiOptimizers, Matt makes important connections within body systems and finds unique ways to maximum human performance. After a personal health scare with his own brain, he’s turned his professional attention to hacking and upgrading the brain in as many ways as possible.

Most people’s brains aren't at 100% due to many factors, he says, like lack of sleep, chronic high stress, an inadequate diet, and overuse of certain drugs and prescriptions.

Mr. Noots, (scientist Mark Effinger) teamed up with Matt on this quest to support brain health and improve cognitive function. After a childhood exploring everything science, chemistry and physics, he joined the US Air Force and became an endurance athlete and bodybuilder. His life, like Matt’s, took an unexpected turn and he struggled with health issues. It took creative, performance-enhancing nutrition to get himself well. He’s now Chief Product Officer for the mind-enhancing compounds and stacks of nootropics at Nootopia and works side-by-side with Matt.

Their newest product, CollaGenius, combines powerful mushroom extracts and collagen into a formula specifically to energize your brain and body. Collagen improves skin health, relieves joint issues, strengthens hair and nails, and prevents bone loss—and it also does your brain a lot of good.  

And here’s what the mushrooms do for you in the right amounts. That’s the key principle—the dose creates the effect. 

  • Lion’s Mane: Boosts BDNF
  • Chaga: A natural anti-inflammatory that supports immunity
  • Reishi: Alleviates stress
  • Cordyceps: Elevates athletic performance and maximizes brain health

 

Together, Matt and Mr. Noots continue pushing limits and finding ways to make your brain operate at its highest capacity. 

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS

Go to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% off.

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Jul 29, 2022
Psychedelic Upgrade: Finding the Right Dose & Approach – Dr. Phil Wolfson & Dr. Julie Holland : 960
00:33:48

IN THIS EPISODE OF THE HUMAN UPGRADE...

…two psychiatric research pioneers open up about the benefits people experience from psychedelic treatments. From mental health conditions to crucial social connections, there’s a dose and approach that can work for you and with your own brain chemistry.

Psychiatrist and psychotherapist Dr. Phil Wolfson, creator of Ketamine Assisted Psychotherapy, leads patients through psychedelic psychotherapy sessions, guiding them through their past and present in an open, altered state of mind. His invaluable work is the result of an intense, many-decades-long clinical practice. He focuses on new pathways for healing depression, PTSD, addiction and other conditions.

“There’s really no right or wrong with psychedelics,” Dr. Wolfson says. “It’s about how do we integrate our lives and relationship in this very difficult time with people and in our beings, and what practices we bring to this whole thing. So, it’s not just about substances.” 

Psychiatrist and psychopharmacologist Dr. Julie Holland explains in her book, “Good Chemistry: The Science of Connection, From Soul to Psychedelics,” why you need connection, how you’ve lost it, and how you might find it again. She believes psychedelics can help. Taken under the direction of a trained psychiatrist, they can catalyze a connection with the self, nature, or the cosmos.

Dr. Holland’s research—with a focus on the parasympathetic nervous system—dives into how you can “turn on” and “tune in” to the brain chemistry that supports connection. At the same time, you can tamp down the fight or flight mode that derails sleep, metabolism, libido and much more. She’s leading new understanding about how your behaviors are driven by the hormones and neurotransmitters that make up good (and bad) brain chemistry, including testosterone, estrogen, dopamine, serotonin and most crucially, oxytocin. 

If you liked this special episode with Phil and Julie, you’ll learn even more from listening to their full podcasts on these topics:


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Jul 26, 2022
How Intuition Can Lead You To Your Highest Self – Joy Martina : 959
01:04:57

IN THIS EPISODE OF THE HUMAN UPGRADE...

…Dave’s travels take him to Amsterdam where he talks with psychic psychologist Joy Martina about intuition, hypnosis and joyful learning. Here’s some of the “how-to’s” you’ll learn about in this episode:

  • How to find the right hypnotist for you
  • How to identify three common misperceptions about hypnosis
  • How to tap into your own intuition and tune into your own wisdom
  • How to recognize your body’s kinesthetic channel 
  • How to learn through joyful and pleasurable experiences
  • How to listen to your gut just as much as your brain
  • How to use your energy for good
  • How to draw from the quantum field 
  • How to connect to your highest potential
  • Ho to create big change in your life
  • How to tune into your environment 
  • How to recognize the benefit from staying stuck in old patterns and make a shift
  • How to notice your triggers and react less to them
  • How to move from an emotionally charged attached position to a grounded, neutral state.


After this episode, head into the podcast library for Joy’s previous conversation with Dave: Intuition is Not a Feeling – #574.

About Joy Martina: Joy Martina, psychic psychologist and a channeler of Christallin Consciousness specializes in high-level intuitive intelligence training for entrepreneurs, business owners and celebrities. She is an author, the creator of the Christallin Oracle Training, a master hypnotist and trainer of trainers.

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Jul 21, 2022
How Sweden’s Herd-Immunity Approach Defied the World – Johan Anderberg : 958
00:42:54

IN THIS EPISODE OF THE HUMAN UPGRADE...

… Swedish journalist Johan Anderberg joins the show to talk about how he captured a rare moment in his country’s history during the worldwide COVID-19 pandemic in 2020.

His book, The Herd: How Sweden Chose Its Own Path Through the Worst Pandemic in 100 Years,” explains this unique time. In it, he gives a fly-on-the-wall account of the herd-immunity strategy that Sweden adopted during the first year of the pandemic. 

  • First, the government instituted no restrictions
  • Then, it declined to order that people wear face masks
  • While the rest of the world looked on with incredulity, condemnation, admiration, and even envy, Sweden stood alone in its decisions.


“We have to value the fact that different countries do different things,” Johan says.

Here’s what you’ll learn by listening:

  • How the Swedish COVID-19 strategy veered far from what the rest of the world was doing.
  • Why "The Swedish Experiment” has been alternately praised and held up as a cautionary tale.
  • In what ways Sweden’s laissez-faire strategy with few restrictions worked.
  • Differing perspectives—no judgment or right/wrong—about the actions and reactions of governments, communities and individual citizens during a medical crisis.


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Jul 20, 2022
Hacking Deep Sleep – Interventions With Dave – George Hanna : 957
00:35:27

In this Episode of The Human Upgrade™...​

 … Dave talks with George Hanna about how to get better deep sleep.

George says he’s been a health and fitness buff for most of his life. Now in his early 60’s, he’s adopted much of the biohacking lifestyle, including sleep hacks. Yet, deep sleep continues to elude him. He and Dave get into factors that could be messing with his circadian rhythm, like temperature, light, overtraining, heart rate variability, glucose monitoring, blood sugar and more. They also go over potential tweaks to:

  • Mushrooms
  • Herbs
  • Amino Acids
  • Testosterone
  • Supplements
  • Thyroid
  • Statins

If you struggle with sleep or simply want to learn to fine-tune the sleep you’re getting, take a listen to this episode for tips and resources.

Listen to the other episodes in the Interventions With Dave series and don’t miss the “Links & Resources” section on the episode web page: https://daveasprey.com/intervention-george-hanna-957/

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

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Jul 14, 2022
How Cold Water Treats Anxiety, Depression and Chronic Pain – Mark Harper, M.D., Ph.D. : 956
00:50:44

IN THIS EPISODE OF THE HUMAN UPGRADE...

…anesthetist and researcher, Mark Harper, M.D., Ph.D., shares how the power of cold-water practices can treat depression, anxiety, PTSD, arthritis, migraines and other health conditions you may be experiencing.

Despite all the attention cold water swimming and immersion has gotten in recent years—thank you, Wim Hof—the scientific community hasn’t taken it very seriously. That’s changing now. Dr. Harper’s research goes beyond what we already know about the benefits of cold-water therapy and lays out best practices for you.

In this episode you’ll learn: 

  • How to safely establish your own customized practice of cold-water swimming
  • The ideal plunge frequency 
  • How to heat your body from the inside out
  • Why using saunas can optimize your plunges
  • The effects of putting your face in cold water vs. just your body
  • Why swimming “in the wild”—lakes, rivers, seas — benefits you even more 
  • How community plays a role in cold plunge practices
  • And more


You’ll also learn about science and case studies found in Dr. Harper’s new book, “Chill: The Cold Water Swim Cure - A Transformative Guide to Renew Your Body and Mind.” He explains how cold water has the ability to impacts us physiologically and mentally.

As Dr. Harper shares his long-awaited evidence on cold-water’s therapeutic power to strengthen the immune system, cell regeneration, and everyday vitality, you’ll come to understand how to harness the power of cold-water swimming. 

If you are looking to up your cold-water therapy game, you’ll get a lot of value from this episode. Dr. Harper says you can start simply, one small movement into cold water at a time: “Your rest, digest, chill out, and anti-inflammatory response comes from putting your face into the water,” he says. He then goes on to other cold-water swim tips. Enjoy!

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Jul 13, 2022
Adventure Upgrade: Going Deep Into Risk, Fear & Awe – Jill Heinerth & Bob Ballard : 955
00:27:49

IN THIS EPISODE OF THE HUMAN UPGRADE...

 …two of the most adventurous people on the planet share what they’ve uncovered, faced and learned through exploration of the planet’s deepest waters. From discovering the Titanic to cave diving in places untouched by any other human, Bob Ballard and Jill Heinerth took risks, dove into fear, and came up for air with tremendous new knowledge. Combined, they’ve spent over nine decades searching the seas and documenting their findings. 

Canadian Jill Heinerth explores the underwater world as one of the greatest cave divers on the planet. She’s considered this generation’s Jacques Cousteau. She’s completed more than 7,500 dives in her career so far and dived deeper into caves than any woman in history. She became the first person to dive the ice caves of Antarctica, going further into an underwater cave system than any woman ever. She’s gone into places in the world where no one had gone before.

Considered a legend in the diving community, she’s spent more than 30 years in submerged caves around the world partnering with National Geographic, NOAA, and various educational institutions and television networks worldwide. She’s also a writer and award-winning photographer and filmmaker who takes a keen interest in the health of the Earth’s oceans.

Learn more about Jill’s lifetime of underwater cave diving in her memoir, “Into the Planet: My Life as a Cave Diver.” “We are capable of so much more than we could possibly imagine," she says.

Bob Ballard explores the vast depths of the oceans uncovering mysteries, proving theories, and revealing artifacts that tell a story about the history of humankind. An oceanographer and marine geologist, he’s led nearly 160 deep-sea expeditions and worked with the Navy on top-secret missions. His underwater career spanning more than 60 years began simply enough as a child with a love of California’s Mission Bay tide pools.

He’s gone on to discover ships thought long lost (the RMS Titanic in 1985) and provide extraordinary new understandings and discoveries in marine geology, geophysics, biology, and chemistry. He’s discovered new life-forms, traced ancient trade routes, developed robots that roam the ocean floor, and opened the underwater world to kids through telepresence. 

Bob's recent memoir chronicles his underwater journeys “Into The Deep: A Memoir from the Man Who Found Titanic.” “Just lots of crazy things have happened, and I'm still at it and I'm not going to quit,” he says.

If you liked this special episode with Jill and Bob, you’ll learn even more from listening to their full podcasts, directly below.


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Jul 08, 2022
Your Life, Stronger: 4 Basics, Brain Power and Belief – Legacy Upgrade ft. Paul Chek : 954
01:53:49

IN THIS EPISODE OF THE HUMAN UPGRADE...

…a legacy upgrade conversation with Paul Chek delivers the goods on how to improve your physical, emotional and mental performance. He lays out what it takes to get into your optimal state—including a higher state of consciousness. 

For more than 30 years, he’s used a unique, integrated approach to treatment and education. Paul gets back to basics and formulates practical systems that work to help you help yourself to get well.

“I look at happiness, movement, quiet, and diet,” Paul says. “I get a holistic picture of their life because you can’t reduce a living philosophy below those four factors.”

Paul's an expert in the fields of corrective and high-performance exercise kinesiology, stress management and holistic wellness. By treating the body as a whole system and finding the root cause of a problem, he’s been successful where traditional approaches have consistently failed. 

And he goes even further into the metaphysical realm.

“The world populace due to the destruction of the environment, due to the chemicals in the environment, due to the electromagnetic pollution, due to overstimulation, due to the lack of sleep, due to the manipulation of people’s biochemistry by medical drug use, … we’re going lower and lower into our levels of consciousness, which is putting us more and more in a fight or flight state, which is making us more and more reactive.”

But you can make a difference within your own life, even going into higher levels of consciousness, Paul explains.

“Every human being has genius within it,” Paul says. “We can use the same technology and the same level of brain power that got us in trouble to reverse it.”

This legacy episode is the full version of a 2-part episode series. Now, you can listen to the entire conversation without interruption. Paul tells it like it is—no holds barred and no BS. You’re going to learn a lot and enjoy his style!

About Paul Chek:  Paul founded the CHEK Institute (Corrective Holistic Exercise Kinesiology) in 1995. He’s a certified neuromuscular therapist and clinical exercise specialist (ACE) who’s studied with experts worldwide from many disciplines. The Chek Institute offers a broad range of educational courses that include at-home study.

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Jul 06, 2022
Spirituality Upgrade: Exploring Energy, Experience & Reality – Deepak Chopra & Abdul Holdijk : 953
00:31:20

IN THIS EPISODE OF THE HUMAN UPGRADE...

…two spiritual masters continue discovering new layers of and models for human experience. This combined episode covers aspects of consciousness, conscious agents, biodynamics, emotional body energy, the Enneagram, homeopathy and much more.

Deepak ChopraM.D., FACP, is a world-renowned pioneer in integrative medicine and personal transformation. TIME magazine described him as “one of the top 100 heroes and icons of the century.” He’s been exploring the intersection of science and spirituality for decades.

Deepak’s 90th book: “Metahuman: Unleashing Your Infinite Potential,” gets into what it means to be “beyond human.” You’ll learn how to question reality, move past limitations constructed by your mind, and enter a new state of awareness. And when you realize a “reality without limits,” you’ll be able to realize your full human potential.

Abdul Hayy Lammert Holdijk has followed a Sufi path for the past 40 years, studying religion and consciousness with a hefty dose of pragmatism. He lectures on topics such as Epigenetics, Neurobiology, the Enneagram, Shadow Work, Voice Dialogue, Love, Dream interpretation, Jekyll and Hyde, Hayy Ibn Yaqzan, and a wide range of other topics related to consciousness and personality development. 

Abdul taught at the American University in Beirut for several years, and then at the American University in Cairo for 35. His profound life story includes adventure, spirituality seeking, questioning tradition and teaching others. He also leads spiritual retreats in Lebanon, Egypt, Oman, and the surrounding region.

If you liked this special episode with Deepak and Abdul, you’ll learn even more from listening to their full podcasts, directly below.


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Jun 30, 2022
Discover Your Capacity to Create, Connect & Love – Susan Cain : 952
00:57:56

IN THIS EPISODE OF THE HUMAN UPGRADE...

...you'll learn some surprising lessons sorrow and longing can teach you about creativity, connection and love. You’ll find out why longing isn’t passive—as most people think—but actually “momentum in disguise.”

Author Susan Cain combines research, the stories of others, and memoir to explain how sadness can be your superpower. “Bittersweetness is the hidden source of our moon shots, masterpieces, and love stories,” she says in her newest book, “Bittersweet: "How Sorrow And Longing Make Us Whole”.

Longing can improve your creativity and fuel a drive to express yourself. Longing coupled with pain can help you to connect to others and provide a common ground that enhances compassion and helps you feel less alone in your troubles. 

Instead of hiding or shying away from feelings like sadness and longing, Susan encourages you to embrace them as part of who you are, and part of what it means to be human. This conversation gets into:

  • How bittersweet differs from melancholy
  • How Acceptance Commitment Therapy helps you manage the “bitter of life” 
  • How sadness is the ultimate bonding agent
  • How the concept of “winners” and “losers” changed over time
  • How to live and work authentically in an environment of enforced positivity
  • How to embrace deep reflection and ask yourself: "What. Are. You. Longing. For?"


Special offer for The Human Upgrade listeners: Go deeper into the topics of Bittersweet and Quiet with Susan’s 30-day interactive online courses. Go to https://www.susancain.net/ and use code ASPREY15 to save 15%.  

More about Susan Cain: She’s the author of “QUIET: The Power of Introverts in a World That Can’t Stop Talking,” which spent seven years on The New York Times bestseller list and has been translated into 40 languages. Her record-smashing TED Talk, “The Power of Introverts,” has been viewed over 30 million times. She’s spoken at Microsoft, Google, the U.S. Treasury, the S.E.C., Harvard, Yale, West Point and the US Naval Academy. She’s an honors graduate of Princeton and Harvard Law School.

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Jun 28, 2022
Mini-Episode: Cool Facts Friday #24
00:10:21

In this Episode of The Human Upgrade™...​

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

 

  • How a gene interferes with memory linking in the brain.
  • How fearful memories are seared into your brain.
  • How a new device stimulates the vagus nerve to help people learn a new language.
  • How global warming impacts your sleep quality.
  • How and why people age, according to a new theory.


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Jun 24, 2022
Nutrition Upgrade: How To Be Food Flexible and Wild – Teri Cochrane & Mareya Ibrahim : 951
00:27:44

IN THIS EPISODE OF THE HUMAN UPGRADE...

…two food experts explain the many ways your food choices influence your body systems—and what you can do differently to improve your gut function, energy and performance. Here’s a look at how essential amino acids and the right proteins can keep inflammation at bay and keep your metabolism humming.

Teri Cochrane, CN, CCP, went down the research rabbit hole when both her son and daughter (at different ages and for different reasons) experienced severe health problems. She not only examined nutrition in-depth, but she also investigated epigenetics and nutrigenomics 

“Disruptors such as pathogens, mycotoxins, stress, amyloids and inflammatory foods work together to impair body balance,” Teri says. “We have found a direct link between amyloids, mycotoxins and these health disruptors in the acceleration of disease.”

She’s developed her own methodology that integrates a multi-level nutritional approach—including biochemistry, nutrition, genetic tendencies, herbology, supplementation and counseling. As the author of the “The Wildatarian Diet: Living as Nature Intended,” Teri lays out how the malabsorption of protein, fat, and sulfur, tamper with gene expression. 

Mareya Ibrahim believes in food flexibility while still focusing on a core system that works. She’s a holistic nutritionist, TV chef, podcast host, and award-winning entrepreneur and inventor with more than 25 years of experience in the food industry. She also founded Grow Green Industries and co-invented the patented eatCleaner line of products.

In her book, “Eat Like You Give a Fork: The Real Dish on Eating to Thrive,” she explains the nuances of clean eating, how to reset your taste buds, and all the ways essential amino acids keep your body functioning.

“Essential amino acids are what fuel us and allow us to regulate our hormones, and flex our metabolisms, and build muscle, and all of the things that we need to be functioning human beings,” Mareya says.

If you liked this special episode with Teri and Mareya, you’ll learn even more from listening to their full podcasts,:


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Jun 24, 2022
Meat Myths: Truth, Lies and Flawed Science – Autumn Smith : 950
01:01:29

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Visit https://paleovalley.com/humanupgrade to get your first 10-pack of meat sticks for only $4.99 + shipping.

Visit https://wildpastures.com/dave to get a special discount for a limited time on regenerative meat delivery.

IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn how eating meat benefits human health, including protein specifics and the clear advantages of regenerative agriculture.

Today’s guest suffered from debilitating digestive issues and crippling anxiety for most of her life. Specialist after specialist told Autumn Smith nothing could be done to alleviate her physical and mental health distress.

As a last-ditch effort, she turned to the power of whole foods. She cleaned up her diet with Paleo-inspired eating and improved her gut in just 30 days. The changes also decreased her anxiety, increased her mental sharpness, and discovered her inner vibrancy. That experience propelled Autumn to help others capture the power of whole foods through quality food products produced by regenerative agricultural practices.

In 2013, she and her husband, Chas, along with another family member and friend, launched Paleovalley. They built a company dedicated to helping people get essential nutrients without added sugars, grains, and other harmful ingredients. With meat being the central focus of their business, they set out to learn all they could about production and regenerative farming.

In 2018, they launched Wild Pastures, a regenerative meat delivery service, and recently opened Wild Pastures Burger Company, their flagship fast casual burger restaurant in Boulder, Colorado.

This conservation gets into the problems with current methods of animal agriculture and possible solutions. You’ll find out more about the nutritional differences of animal products depending on how they’re raised. Autumn says meat labels can be tricky, too, so she breaks down the jargon and tells you what to look for and what to avoid.

Autumn advocates for meat’s many advantages and works to dispel the myths that continue to persist about meat consumption. From soil to farming to raising animals humanely, building community and managing economies, Autumn talks about how to make choices that are right for you and everything around you.

More about Autumn Smith: Autumn holds a master’s in Holistic Nutrition and currently is a doctoral candidate in Holistic Nutrition. She’s a Functional Diagnostic Nutrition Practitioner, an Eating Psychology Coach certified by the Institute for the Psychology of Eating, and received Soil Advocacy Training by Kiss The Ground. She hosts the popular Optimize Paleo podcast.

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Jun 21, 2022
Hacking Mast Cells, Hormones & Mold– Interventions With Dave – Lisa B. : 949
00:59:30

In this Episode of The Human Upgrade™...​

… Dave talks with Lisa B. about the frustration she’s experiencing with her health conditions. She says she lives a healthy lifestyle and does the “right things” and still struggles with chronic low energy. Her kids often say, “you never feel well, mom.” She agrees but finds it difficult to explain why. 

Now in her early 50s, she’s had panic attacks and anxiety since childhood and has taken many types of anti-depressants throughout her life. She also struggles with OCD.

She’s experienced long-time hormonal imbalances, including painful periods, acne, fertility problems, and ongoing PMS “flu” that she says takes over her life during her cycles. She suffers from aggressive seasonal allergies and has a shellfish allergy. 

She’s been on Accutane, was diagnosed with Lupus in college and also diagnosed with exercise-induced urticaria and Mast Cell Activation Syndrome. She got COVID in 2021.

In this “Interventions With Dave” episode, Dave examines what’s going on with Lisa’s varied symptom. They discuss what’s working and what’s not, and what can help her gain more energy and control of her health. The conversation gets into a bunch of topics, like:

  • PMS “flu” (with sore throat, hot tongue, achy, brain fog, no energy, feverish feeling with no fever present, painful periods) 
  • Hormones, the Wiley Protocol and testosterone
  • “Mold cough” and other symptoms of mold
  • OCD and anxiety
  • MTHFR gene mutation 
  • Histamine, Mast Cells and Mast Cell Activation Syndrome
  • Allergies
  • And much more…


Find biohacking tips, tools and resources particular to this episode on the episode web page: https://daveasprey.com/interventions-with-dave-lisa-b-949/

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

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Jun 18, 2022
How Minerals Combat Glyphosate’s Harm – Caroline Alan : 948
00:49:18

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to beamminerals.com/advancedset. Use code DAVE to get 20% off.

IN THIS EPISODE OF THE HUMAN UPGRADE™...

 …you’ll find out how plant-based humic substances have the power to stop and reverse the effects of glyphosate damage in both humans and soil.

Caroline Alan, co-founder and CEO of BEAM Minerals, explains how minerals provide your body systems with critical cellular support, how they get depleted and how you can replenish them. She goes even further to talk about glyphosate’s harmful effects on human health and soil health, particularly when it comes to minerals.

In her former corporate career of software development and business consulting, Caroline experienced problems physically, mentally and energetically. She struggled with issues like life-long gluten intolerance, whole-body inflammation, leaky gut, chronic headaches, flat-lined adrenals and low thyroid. Her chronic health issues didn’t resolve until she began taking plant-based humic and fulvic minerals.

This cellular support changed her life so dramatically, she started deep research into the science of minerals and co-founded BEAM Minerals. 

Then she kept going and began to look more closely at the current problems with farming in soils that have become unproductive due to a lack of microbial and mineral content. She investigated the effects of glyphosates on soils and in the human body and found:

  • One of the root causes of unhealthy soil can be linked directly to glyphosate use in modern production farming.
  • One of the root causes of mineral depletion and chronic illness in modern humans points directly to glyphosate ingestion.


The bottom Line? We all have glyphosates in our bodies. Here's what it can do: Suppress critical enzymes, create gut dysbiosis, chelate minerals from your system, reduce mitochondrial function, and cross and affect the blood–brain barrier. Studies also show more use of glyphosate can lead to an uptick in chronic and acute health conditions.

Research finds that plant-based humic and fulvic substances offset glyphosate harm. This conversation will help you recognize symptoms of mineral depletion in your own body. You’ll get practical tips about how to use 100% bioavailable, plant-based fulvic and humic mineral supplementation in easy forms like liquids and topical spray.

BONUS: For research links and other resources about glyphosate and humic/fulvic substances, visit daveasprey.com/glyphosate.

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Jun 17, 2022
How to Build a Better Brain, Brand & Business – Patrick Schwarzenegger : 947
01:05:27

IN THIS EPISODE OF THE HUMAN UPGRADE™...

 … you’ll get tips about how to lead a brain healthy lifestyle and how to keep perspective along your own entrepreneurial journey. 

Activism, acting and entrepreneurship are wired into Patrick Schwarzenegger’s DNA. He thoughtfully balances each passion through his work as an Alzheimer’s advocate, actor, investor and food founder. 

Patrick’s known for his trend-spotting abilities in the better-for-you food and beverage industry. He got into the fast-casual Blaze Pizza franchise when he was just a teen. That experience solidified his interest in health and wellness: “invest solely into entrepreneurs and companies that were providing Americans with the healthier alternative." He’s now an active investor and advisor to numerous brands and helps founders scale their emerging businesses to the next level.

His latest venture encourages brain health at every age and supports programs, research, and lifestyle choices designed to make your brain work better. Patrick co-founded a new brain health food brand called “MOSH” with his mom, Maria Shriver, designed specifically to up-level your brain function.

“We really want it to be a brand that was created out of a mission and out of the why, and not so much the what,” Patrick says. … “We want to be a brain health company and also educate consumers and raise money and donate that to the Women's Alzheimer's Movement. So, it's been an amazing journey.”

A journey with its share of mishaps, too: “We had so many things that went wrong and that was kind of the fun part was learning about that and finding ways to fix it. That's wanting to be an entrepreneur or that's embarking on that journey, you're going to have speed bumps. You can do as much homework as you can and want and try to perfect everything before you launch, but things come out of left field every single day.”

He’s on the show to discuss entrepreneurship, how to invest, how to build brands, how to hire the right people and what’s possible for high-functioning brains at every age.

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Jun 15, 2022
Mushroom Upgrade: Big Benefits for Human Biomes and Natural Ecosystems – Paul Stamets & Julian Mitchell : 946
00:31:31

IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn how your cells, mitochondria, immune system, sleep patterns, inflammation, nerve growth pattern, and energy levels all benefit from mushrooms. These fungi are full of compounds and nutrients that your body will love. There’s a whole lot of science behind this now.

In this special podcast edition, you’ll hear how two mushroom experts are studying and harnessing the amazing powers of mushrooms for the deepest parts of human biology and the natural environment. 

Paul Stametsis a speaker, author, mycologist, medical researcher and entrepreneur. He’s considered an intellectual and industry leader in habitat, medicinal use and production of fungi, and he considers himself a “mycological warrior.” He’s spent over four decades in the Pacific Northwest studying and researching the world of mushrooms. Listening to him describe, decode and illuminate the workings of the mushroom world is an enthralling experience, indeed. 

He says we’re intertwined with mushrooms at a cellular level. He believes that habitats have immune systems—just like people—and mushrooms are cellular bridges between the two. Our close evolutionary relationship to fungi can be the basis for novel pairings in the microbiome that lead to greater sustainability and immune enhancement. And from neurogenesis to our microbiome to our mitochondria, fungi are linked to us. He’s also making some amazing discoveries having to do with bears, bees, butterflies and biodefense.

Mycelium Just Might Save the Bees, And Us – Paul Stamets – #624

Learn more at fungi.com 

Julian Mitchell, —co-founder and CEO of the Australian-based company Life Cykel—and his team work with mushrooms as innovative food sources and medicinals in Australia. “Mushrooms and mushroom-based foods are going to play a huge role in the future of food,” Julian explains. “They grow quickly requiring very little resources in terms of water, power, and land. They have an amazing nutritional profile, and of course, they are 100% natural.” … “Mushrooms are almost an uncharted continent, with infinite applications not just in food but in biotechnology.”

For day-to-day use, you’ll want to go with cooked, not raw, mushrooms. For those of you who aren’t fans of eating mushrooms, there’s an option for you, too: “Having it as a tincture makes it very easy to add to a coffee, add to a tea, add to a smoothie,” Julian says. “It’s quite tasteless and at the same time micro-dosing it in small amounts straight into your mouth is a great way to have it as well and absorb it straight into your blood system.” 

Mushrooms Are Your New Anti-Aging Strategy – Life Cykel #603

Learn more at lifecykel.com

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Jun 10, 2022
Breathing Upgrade: Get It Right & Catch Some Serious Air – Patrick McKeown & James Nestor : 945
00:29:27

IN THIS EPISODE OF THE HUMAN UPGRADE...

 … you’ll learn why every breath you take makes a difference in how your entire body functions. The way you breathe affects the quality of your life and every one of your body systems. Full stop. This goes for adults and kids alike.

In this special edition, breathing experts Patrick McKeown (“THE BREATHING CURE: Develop New Habits for a Healthier, Happier, and Longer Life”) and James Nestor (“Breath: The New Science of a Lost Art”) approach the topic from diverse perspectives, but agree on a lot. Especially the benefits of nose breathing and the detriment of mouth breathing.

They explain the biochemical, biomechanics and psychological components of how you breathe. They also present exciting new research in pulmonology, psychology, biochemistry and human physiology that shows how making even slight adjustments to the way you inhale dramatically influences things like:

  • sleep and snoring
  • fitness and athletic performance
  • brain function
  • focus and concentration
  • oxygen intake
  • heart rate and blood pressure
  • blood sugar
  • internal organ function
  • nervous system
  • respiratory health
  • asthma and allergies
  • autoimmune disease
  • sex
  • female hormones
  • pain
  • stress and anxiety 


That's just the start of what you can change when you change your breathing. Big claims, yes. All true. And even bigger benefits for you.

Breathing can nurture your body, center you, and rebalance you. When you start harnessing the power of your breath, you're going to feel incredibly better than you do right now. 

Patrick McKeown, an author, educator and one of the world’s leading breathing re-education experts, has researched breathing for more than two decades. Listen to more: Shut Your Mouth! Nose Breathing Improves All Your Body Systems – Patrick McKeown – #835

James Nestora San Francisco-based science journalist, author, surfer, free diver, adventurer, and speaker, set out on a decade-long quest to find out where our breathing went wrong—and how to fix it. Listen to more: Breathing Essentials That Will Change Your Life – James Nestor – #751

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Jun 08, 2022
Upgrade Spotlight: How a Peptide Gets Under Your Skin to Combat Aging – OneSkin : 944
00:29:44

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://www.oneskin.co and use code DAVE15 to get 15% off your first-time purchase.

IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. 

You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. 

Introducing OneSkin! During this Upgrade Spotlight, you’ll learn about new products designed to target skin aging at the molecular level and promote skin and body health. You’ll also find out the science behind OneSkin’s formulas and why they are considered “daily topical supplements.” They can help you maintain functional and resilient skin as you age. 

OneSkin topical supplements are powered by a proprietary peptide: OS-01, which decreases the accumulation of aged/senescent (zombie) cells in the skin. By targeting the major driver of skin aging, OS-01 has been scientifically proven to:

• Repair cellular damage, including UV damage

• Increase epidermal thickness

• Improve barrier function

• Increase the activity of genes associated with collagen, hyaluronic acid, and elastin production

• Reverse the biological age of skin

“So this peptide has a very interesting profile because it's small enough to penetrate and it's super safe,” explains Carolina Reis Oliveira, Ph.D., scientist, CEO and co-founder of OneSkin. “There is no toxicity, no irritation. We've done all the recommended studies by FDA for personal care products, and, has this beautiful effect of reducing the accumulation of senescent cells, and also reduces the release of inflammatory markers, and increase the production of hyaluronic acid, elastin and collagen. So, in the end, there's a molecule that has all these attributes that's very important for healthy skin, overall.”

Another exciting part of this peptide work includes MolClock, the first skin-specific molecular clock, capable of reliably and accurately determining the biological age of skin. This was created by OneSkin’s team of female PhD-level longevity scientists as part of its research and development platform.

Carolina relocated from Latin America to Silicon Valley in 2016 to co-found OneSkin and lead the development of the company’s disruptive skin rejuvenation technologies. She holds a Ph.D. in Immunology, along with degrees in biochemistry, stem cell biology and tissue engineering. 

Her team of co-founders includes three other female scientists with additional expertise in skin regeneration, bioinformatics, genomics, immunology and molecular biology. Among them, they’ve invented numerous patents and have published nearly 100 peer-reviewed papers in scientific journals.

This episode explores exciting new information about improving skin health at the molecular level for the long-term. When you do that, your body will be more equipped to defend itself from environmental stressors and aggressors, especially with age. 

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Jun 04, 2022
How to Manage Sugar for a Better Brain and a Longer Life – Colleen Cutcliffe, Ph.D. : 943
00:57:56

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn about emerging science that points to the effects of sugar on your gut microbiome and metabolism and the connections between sugar, your mental acuity and longevity.

Biochemist and molecular biologist Colleen Cutcliffe, Ph.D., continually searches for new ways to improve your gut health and help you live longer. As CEO and co-founder of Pendulum Therapeutics, she works to turn scientific discoveries into real products that hack and heal your microbiome and its associated body systems. At Pendulum, her team identifies and isolates new bacterial strains then combines those new strains to create unique probiotics.

“We really worked hard on ways to modulate post-postprandial glucose spikes through the microbiome,” Colleen says. The result? Pendulum’s Glucose Control lowers blood glucose spikes by 33 to 34% for people with type 2 diabetes. “What we didn't realize was how many people who don't have type 2 diabetes were going to end up benefiting from it.”

This conversation homes in on sugar management and a broad range of research that’s exploring what you can do about managing your glucose to keep up your mental acuity (less brain fog, sharper thinking) and live a longer life.

 Science has discovered that as you age:

  • You have reduced ability to metabolize sugar. 
  • Your microbiomes become less diverse and depleted of certain key strains that are important for sugar metabolism.
  • If you improve glucose control, you see reduced neuronal inflammation and improved cognition.


In the past decade, especially, sugar dominates a lot of the conversation around diet and health. It’s been studied, substituted, moderated, restricted and demonized. With that type of focus, you lose the bigger point.  

“You can't completely cut out sugar,” Colleen says. “You do need sugar. Not all sugar is bad for you all the time. Every cell in your body, except for your colon cells, need glucose in order to survive, in order to replicate, in order to perform functions. All of the things that allow you to be a human being require some amount of sugar."

She wants you to know what’s happening to cause the change in metabolic processing as you age and what you can do about it, like:

  • How to understand your blood glucose range and what fluctuations mean.
  • How to track your blood glucose and what to do about peaks and dips.
  • How to improve your focus, sharpness and mental endurance through diet and fitness.


“I'm a scientist, so I'm always going to say more data is better,” Colleen explains. “[Especially] when you're trying to make improvements and you're making these micro-adjustments in your life, and you want to understand what impact are they having.”

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Jun 03, 2022
How 5 Self-Coaching Steps Get You to Your Goals – Jason Goldsmith : 942
01:06:34

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

 …you’ll learn how to connect the principles of self-coaching to biohacking. You may already be doing some things, but this topic will help you fine-tune your approach in simple, yet powerful, ways.

High performers typically know the value of coaches: experts who can train them and guide them toward goals. But what if you could become your own coach? 

Podcast guest Jason Goldsmith emphasizes the value of combining the mental and physical aspects of human performance. He knows, too, that it’s important to learn to coach yourself to achieve any kind of life success you go after. Self-coaching doesn't mean you do it all on your own, it means that you take charge of yourself, for yourself.

This episode brings these concepts together so you can be in charge of yourself and be confident and purposeful when making decisions. 

A globally recognized performance coach and founder of Goldsmith Performance, Jason’s best known for his work with golfers, from junior, to amateur to professional skill levels. He also coaches athletes from other major sports, as well as Fortune 500 executives.

He’s distilled his knowledge and partnered with David Novak, cofounder & former CEO and Chairman of Yum! Brands (owner of 45,000+ restaurants) to present sports and business coaching for high performance. They’ve created a practical guidebook for you to learn how to be your own best coach: “Take Charge Of You: How Self Coaching Can Transform Your Life and Career.”

This conversation covers strategies to develop an understanding of who you are and what drives you. “That is a crucial part of choosing your SBT (single biggest thing): it should feel big, important, impactful, even aspirational,” Jason says in his book. “There is a difference between setting a goal and choosing a destination.”

You can outline a process with that knowledge that sets you up for success. And then add in something you may not have considered: 

“Joy is a critical ingredient, and I don't think enough people have enough joy in their day-to-day life,” Jason says. “It’s really important for people to know what it is that brings them joy and what are the things that diminish their joy. So, if I was able to biohack my day, what are the things I do every single day that make me feel the best possible version of myself? But then what are the things that get in the way of that joy? And then how do I eliminate those joy blockers and have more of those joy builders?”

You’ll find out how in this episode! 

“Take Charge of You” includes do-it-yourself lessons, stories, tips, and questions to ask yourself to track your personal growth and professional development. You can follow this blueprint for self-coaching, no matter what your goals may be.

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Jun 01, 2022
Mini-Episode: Cool Facts Friday #23
00:17:17

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Drugs that cut down cancer risk by 61% aren't really drugs.
  • Take the right type of Vitamin D for the most benefit.
  • Stressing cells in the sauna could help reverse neurological disease.
  • A new discovery in brain communication and function.
  • Making stem cells younger in less time.
  • Active brown fat could be a marker for pre-diabetes.


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May 27, 2022
How to Slow Down Your Biological Aging – Morgan Levine, Ph.D. : 941
01:06:01

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 …you’ll learn how biological age, rather than chronological age, is the primary risk factor behind diseases like cancer, heart disease, diabetes, strokes, even Alzheimer’s. Scientific discoveries show chronological aging may be written in the epigenome, those chemical tags attached to your DNA that control the way DNA operates.

We’re finding out more about both types of aging because of scientists like Morgan Levine, Ph.D., a leading voice in the field of aging and longevity science. She focuses her research on the science of biological aging, emphasizing health span over lifespan. 

“If you take the difference between someone’s biological age and chronological age, it should predict the things we care about, the actual things we're trying to prevent—so death, disease,” she says. 

She’s an assistant professor of pathology and the Director of the Laboratory for Aging in Living Systems at Yale University School of Medicine. Her team looks at using bioinformatics to quantify the aging process and test how lifestyle and pharmaceuticals alter the rate of aging. 

She’s also a founding Principal Investigator at Altos Labs, a biotech company that focuses on cellular rejuvenation programming to restore cell health and resilience.

Today, she’s going to talk about the science of aging and longevity explored in her new book, “True Age: “Cutting-Edge Research to Help Turn Back the Clock.” Three main drivers—health behaviors, recent stressors and adversity, and genetics—determine your biological aging. She shares how to measure your own biological age and why you should track your aging regularly. 

This conversation gets into topics and makes them make sense for your own aging, like:

  • Epigenetics & epigenetic clocks
  • DNA methylation & telomeres
  • Cell lifespan 
  • Ageotypes (molecular assessment of aging)
  • Phenotypic age
  • The “Ceiling” effect
  • The “CALERIE” trial
  • Nutrition & aging (plants, fasting, ketosis)
  • Fitness & aging (energy & brain health)
  • Rest & relaxation (sleep & biological programming)


Morgan gives great takeaways on how you can make lifestyle changes to maintain your youthfulness—both inside and out—with low-risk, data-driven biohacking. 

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May 27, 2022
How Focus and Attention Powers Your Mind – Amishi Jha, Ph.D. : 940
01:15:47

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’re going to find out why you’re missing 50% of your life to fractured attention and distraction and what it’s doing to your brain. 

Podcast guest Amishi Jha, Ph.D., a neuroscientist and professor of psychology at the University of Miami, researches how people pay attention. She co-founded the Contemplative Neuroscience for the Mindfulness Research and Practice Initiative at the University of Miami and serves as its director. For more than 25 years, she’s researched the science of attention through intensive work with the U.S. Military, first responders, medical professionals, business leaders, and elite sports teams.

She’s found that attention Is both your superpower and your kryptonite. 

As a superpower, attention allows you to time-travel in your mind (future and past), highlights what’s important, helps you problem solve, and shuts out distractions, she explains in her book, “Peak Mind: Find Your Focus, Own your Attention, Invest 12 Minutes a Day.” 

When attention is compromised, it’s your kryptonite because it impacts your cognitive function, social engagement, and emotional balance, she points out. The three main forces that degrade attention include, 1) the amount of stress you’re under (and how you’re managing it); 2) being in a crappy mood; and 3) threats real or imagined.

And when your attention gets fractured, you often default to tactics that fail to pull it back together. Amishi’s got great insights in her book that allow you to understand why this happening. When you know what’s going on, it's easier to find your focus.

It’s absolutely possible to change your brain to become more attentive, present, and productive through mindful techniques and daily focusing practices. Amishi’s research shows that mindfulness gives you a sense of control over your mind and allows you to stop negative thinking before it hijacks your brain and body.

The type of mindfulness practice you choose isn’t as important as how consistently you actually do it. The minimum effective dose equals 12 minutes a day, five days a week.

Listen on to a conversation that gives you practical tips on how to re-capture your attention, train your brain and perform at your peak.

More about Amishi Jha, Ph.D.: Amishi earned a Bachelor of Science degree in Biological Psychology then went on to earn a Ph.D. in Psychology (Cognitive Neuroscience) from the University of California–Davis. She completed post-doctoral training at the Brain Imaging and Analysis Center at Duke University in functional neuroimaging. She leads research on the neural bases of attention and the effects of mindfulness-based training programs on cognition, emotion, resilience, and performance. Her work has been featured at NATO, the World Economic Forum, and the U.S. Pentagon. 

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May 24, 2022
Hacking Your Biohacks for Better Sleep, Fitness & Weight Control – Interventions With Dave – Sean Plotkin : 939
00:48:09

In this Episode of The Human Upgrade™...​

… Dave talks with Sean Plotkin about changing up his current biohacking routine to get even better results. You’ll find out how to maintain a high quality of life amid the “hustle” that can take up a lot of your everyday life.

In his mid-40s, Sean’s doing a lot to improve his energy, keep his body strong and stay ahead of aging. But, he says, the weight keeps creeping up and he’s concerned about his thyroid function. He has an intense weekly exercise routine and could use some help with nutrition before and after his fitness sessions. He also wants to tackle sleep, believing his isn’t as optimal as it could be.

He’s doing a lot of things right, including: supplementing with glutathione, using ozone, wearing a continuous glucose monitor, cooling his sleep with an Ooler Sleep System, tackling how he feels with Hapbee, managing stress and performance with NuCalm, upgrading his brain at 40 Years of Zen, and investing in a hyperbaric chamber and sauna for home use. 

In this “Interventions With Dave” episode, Dave examines what Sean’s doing, what’s working or not, and what he can do to reach his peak performance consistently. They break down:

  • Nutrient availability (No. 1, energy; No. 2, protein; and No. 3, carbs)
  • Blood glucose and insulin resistance
  • Cortisol and stress
  • Hormones
  • Cognitive function
  • Nutrition
  • Pre-diabetes
  • Fatty liver
  • Inflammation
  • Cold therapy
  • Cholesterol
  • Metabolic health
  • Brain health
  • And much more!


Sean’s already got great awareness, tools and data to work with. Along any journey, it takes some experimentation—and time—to find that sweet spot that makes you feel like a million bucks. 

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

Don't miss the previous episodes in the Interventions With Dave series:

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May 21, 2022
Your Get-Smart Guide to CBD & Chinese Herbs – Chloe Weber : 938
00:58:36

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn about all things CBD, hemp and THC: what current research says, why quality matters, and how to get real results. Paired with particular Chinese herbs, the benefits to you increase even more.

In the last few years, CBD was a trend, then the market got saturated, and then people said: “I tried CBD and nothing happened.” That’s unfortunate, because experts like acupuncturist, herbalist and Chinese Medicine practitioner Dr. Chloe Weber know exactly what works—and how. 

There are four main ways hemp supports the mind and body, and this conversation gets into the mechanisms of them all: Anxiety and stress, GI support, immune support, and pain management/inflammatory disorders.

You’ll also find out:

  • The differences between full spectrum (with 0.3% THC) vs. isolate vs. pharmaceutical cannabis.
  • How your body’s endocannabinoid system works and why it’s your master regulator.
  • What endocannabinoid deficiency means for your body.
  • How to take CBD and how long it takes to experience its effects.
  • How pairing CBD with Chinese herbs can benefit your body and brain, and power your performance.
  • What to look for in high-quality hemp products.
  • How to maneuver through cannabis strains and THC potencies.
  • How to decide between CBD oils, capsules, topicals for your particular health needs.
  • Common misconceptions about and censorship of CBD.
  • What new cannabinoids are coming onto the scene, like CBG and CBN.

Chloe founded Radical Roots Herbs, a company that offers full-spectrum hemp product and also combines CBD with Chinese herbs to boost the power of both.

“By calming the nervous system and supporting our endocannabinoid system,” Chloe says, “we're actually able accept, absorb and process the Chinese herbs in a more dynamic way."

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May 20, 2022
Bonus: Biohacking Surgery & Recovery with Dave Asprey
00:07:43

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

… I will teach you everything you would ever want to know about before surgery, during surgery and after surgery, so that you come in strong, you have a better surgical experience, and you recover way faster than you're supposed to. 

Research shows that if you live in America, you’re likely to have an average of seven surgeries in your lifetime. Wouldn’t you want to know how to go in at your best so you can recover at your best? 

This was my thinking when I went under the knife last year. 

In the hours and days that followed, I blew my doctor’s mind. He had never seen a recovery like mine. 

As the Father of Biohacking, I never shy away from an opportunity to blow the lid off what we think is biologically possible. And then I share what I’ve found with the world.

In Heal with Dave, my new documentary, you’re going to learn all of the methods I used to heal without pain and recover to the fullest and beyond. I’ll teach you how.

If this sounds interesting to you and you want to know what to do to have control of your biology at a time when frankly, a lot of people take quite a while to recover and there's increased risk of all kinds of bad things like infections, systemic issues, just not healing very well and building strong tissues, go to daveaspery.com/heal

Watch the documentary, use the resources. It's my gift to you! 

“Heal with Dave” Documentary: https://daveasprey.com/heal/

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May 17, 2022
Discover Your Attributes & Get More Out of Yourself – Rich Diviney : 937
01:18:13

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

… you’ll learn why developing your attributes may be more important than skills when it comes to getting more out of yourself. Attributes are wired into your internal circuitry, always running in the background, says Rich Diviney. You’re born with attributes. They’re elemental and considered innate traits—not to be confused with personality traits.

Rich, a retired Navy SEAL commander, bestselling author, and leadership and human performance expert, explains how attributes determine how you absorb, process, and respond to the world around you. By knowing this, you’ll be able to assess your own attributes and put them into action with SMART steps.

In his book, “The Attributes: 25 Hidden Drivers of Optimal Performance,” Rich shows you how mindset, optimism and becoming uniquely resilient to stress can help you become a better human. His approach identifies core attributes needed for success in personal or professional tasks.

His ability to choose the right people to be in elite performance groups—like the U.S. Navy SEALs—could be considered a superpower. As the officer in charge of training for a specialized command, Rich was part of the SEAL selection process. He pared down a group of exceptional candidates to a small cadre of the most elite optimal performers. How did he do it? By looking at attributes.

It’s Rich's belief that SEALs are not born extraordinary. Instead, they’ve mastered their own mindset to get the most out of their innate abilities to make themselves extraordinary. He believes we all have the power to do this.

In “The Attributes,” you’ll find examples of attributes within five distinct categories plus a couple more that don’t fit so neatly: Grit, Mental Acuity, Drive, Leadership and Teamability. 

So, what are attributes and how are they different than skills? 

“A lot of times we get seduced by skills, and we don't think about attributes,” Rich says. “And the reason is very simple: skills are not inherent to our nature. They're very visible, which means they're very easy to assess, measure and test and you can put scores around them and stats around them. … Attributes are inherent to our nature. We're all born with levels of adaptability and situational awareness and resilience.  Attributes don't dictate our behavior or director behavior; they inform our behavior.” 

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May 13, 2022
A Crash Course in How to Build Radical Confidence – Lisa Bilyeu : 936
01:11:32

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 …you’ll learn that to be a high performer, you’ve got to have radical confidence to achieve whatever goals you set for yourself. Today’s guest, Lisa Bilyeu, explains how real confidence is an inside job, not something you gain from outside validation. 

When Lisa co-founded Quest Nutrition, she was a self-professed housewife boxing protein bars in her living room. The company grew 57,000 percent in its first three years and became a billion-dollar brand. Her learning curve was steep and fast and filled with things she didn’t know how to do—yet. 

She went on to co-found (with her husband, Tom Bilyeu) and serve as president of Impact Theory Studios. It’s a digital-first studio that produces entertaining original content focusing on themes of empowerment. That content has been viewed over half a billion times by a global audience.

Lisa oversees in-house development of projects focused on female-driven content for multiple platforms. She hosts the digital series, “Women of Impact.”

In her first book, “Radical Confidence: 10 No BS Lessons on Becoming the Hero of Your Own Life,” she shares her journey from a housewife to successful entrepreneur with relatable lessons, anecdotes, and lots of humor.

She explains how the “Purgatory of the Mundane” is even more dangerous than hitting rock bottom. She dishes tough love for those of you who are stuck in mind loops that hold you back.

From ditching the fairy tale to getting off the couch to putting on goggles when the shit hits the fan, Lisa’s got realistic tips to get you moving. An important part of that momentum is setting boundaries: material, physical, and mental and emotional. She shows you exactly how.

She also suggests a fresh perspective on a few things that can help you build “radical” confidence:

  • Manage the voice in your head
  • Set clear boundaries
  • Learn from your mistakes
  • Keep your goals top of mind
  • Maintain self-awareness around your emotions and triggers

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May 11, 2022
Upgrade Spotlight: Find Your Footing in Minimalist Footwear – Xero Shoes : 935
00:46:07

IN THIS EPISODE OF THE HUMAN UPGRADE...

 …you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. 

You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. 

Introducing Xero Shoes! During this Upgrade Spotlight, you’ll learn how minimalist footwear reduces injury, improves foot strength and supports healthy feet. You’ll learn that getting grounded is a good thing.

Today’s guest—serial entrepreneur Steven Sashen—is a competitive sprinter. He knows the mechanics of human feet. He also knows what it feels like to move in shoes that suck. 

So, he and his wife, Lena Phoenix, founded the footwear company Xero Shoes. They ran headlong into shoe history and shoe science to intentionally create “a MOVEMENT movement” of people with happy, healthy, strong feet in addictively comfortable footwear. 

“A quarter of the bones and joints of your whole body are in your feet and ankles,” Steven says. “They're supposed to bend and move and flex just like any other joint. If you're wearing shoes that don't let them do that, that function tries unsuccessfully to move into your ankle, your knee, your hip and your back joints. Those joints aren't built for those micro motions that keep you balanced, that give you agility and mobility.”

Your feet, and by design the rest of your body, know something’s off with cushioned shoes. So does Steven.

“The value of natural movement, the importance of foot health, and all the things that relate to foot health got me going,” he says. “But what really catalyzed it was discovering that what the footwear industry has been doing for 50 years is lying to people– selling people on ideas that they know don't work, but they can't pull back. They can't tell a different story, because they've been promoting this story for so long about arch support, motion control, padding, cushioning, etc.” 

Research published by the American College of Sports Medicine in 2021, “Stepping Back to Minimal Footwear: Applications Across the Lifespan," showed that minimal footwear leads to improved musculoskeletal health across your lifetime. 

“It’s all about natural motion,” Steven explains. “Our ancestors didn't have a problem being on their feet all day, every day. It wasn't because they're different from us, it was just that they got used to using their feet correctly. We can still do that any day, anytime, any of age.”

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May 07, 2022
How to Double Your Energy – Ari Whitten : 934
01:01:33

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll find out why you’re tired, how to fix it and ways to increase your energy. Fatigue is a hidden epidemic, with chronic fatigue syndrome being the most severe end, but most people (in the U.S.) are experiencing some level of being flat-out tired as hell.

Guest Ari Whitten, Ph.D. (Cand.), CES, PES, says that as a culture, we have normalized fatigue. In his newest book, “EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy,” he explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatigue). However, the true fatigue epidemic affects 50 to 100 times more people.

This episode’s discussion gets right into the role of mitochondria in human energy. Ari’s research (420 citations in “Eat for Energy”!] is clear. The cause of fatigue is mitochondrial dysfunction, he says. And the biggest factors that affect your mitochondria include:

  • Circadian rhythm dysregulation and poor sleep 
  • Carrying too much body fat and too little muscle mass 
  • Poor gut and microbiome health 
  • Blood sugar dysregulation 
  • Nutritional toxicities and deficiencies 
  • Neurotransmitter and hormone imbalances

 

So what can you do to increase your energy currency? A lot, as it turns out. When you understand factors like resilience, cell defense, nutrition and supplementation, you’re on your way to better energy. In this conversation, you’ll learn:

  • what’s causing the dysfunction in your mitochondria and how you can repair these critical energy cells. 
  • strategies that will double your energy levels. 
  • 7 top supplements (and more) that help get your mitochondria back on the energy track.

 

Ari has been studying and teaching natural health science for more than 25 years. He went through his own battle with chronic fatigue that inspired his obsession with energy. For the past seven years, he's focused specifically on improving human energy. His education and work in this area touches on critical aspects of human health from nutrition to physical training, to light science, to psychology, and more. 

He created The Energy Blueprint science-based lifestyle programs that target brain energy and mitochondria. He also hosts The Energy Blueprint podcast that features world-wide experts on the subject of understanding fatigue and how to get more energy. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

May 06, 2022
Relieve Your Back Pain in 4 Steps – Dr. Marcella Madera : 933
01:06:16

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

… you’ll meet a holistic neurosurgeon who’s evolving spine care away from cutting. Dr. Marcella Madera’s integrative approaches to spine problems pair science with holistic healing modalities. This means way better healing for you.

Dr. Madera’s innovations in spine treatments include the “Aqua Method,” where photobiomodulated platelet rich plasma meets functional tissue mobilization and movement. You’re going to get exciting new information about this effective form of regenerative medicine and find out if this treatment may be right for you. “It's a very nuanced discussion,” says Dr. Madera. “It's very patient specific. It's very injury specific.”

“The term Aqua really gives a description of what we're trying to create in the body and that is more fluidity,” she explains. “And also, water, aqua, is pure. It’s intense at times, depending on the form. And it is soothing at times, depending on the form. And that is how our treatment goes.”

Dr. Madera’s four-part system includes: Reveal, Restore, Revitalize, Revel. You could benefit whether you have an old or new injury, or chronic pain.

During this episode, she explains how each part is interconnected and helps you heal your spine, or even knee, problems. The Aqua Method’s three-day immersive experience includes a full team of experts focused on your biology, your energy and your state of mind.

Dr. Madera, a board-certified neurosurgeon, trained extensively in conventional medicine. Her expertise in spine care includes surgical treatments, approaches, and techniques for degenerative spine disease, spine tumors, and degenerative deformity.

 She started a private practice in in Austin, Texas where she combines her technical spine care with stem cell treatments and holistic modalities like herbs, energy modalities, Chinese healing practices, autogenic training and diet modification.

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get a $1,000 discount on the Aqua Method at Austin Integrative Spine in Austin, Texas. Call the clinic at 512-817-4600 and mention discount code DAVEASPREY.

More about Dr. Marcella Madera: She’s experienced in open surgery, minimally invasive surgery, endoscopic spine surgery, and regenerative/stem cell procedures. She’s been an assistant professor of Surgery at the University of Texas at Austin Dell Medical School. She also travelled throughout Europe and the U.S. to learn progressive endoscopic techniques and regenerative medicine practices. She completed a Spine Fellowship and faculty instructorship at Johns Hopkins School of Medicine.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

May 04, 2022
Mini-Episode: Cool Facts Friday #22
00:15:43

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • GlyNAC (glycine and N-acetylcysteine) can correct glutathione deficiency, oxidative stress, mitochondrial dysfunction and mitophagy abnormalities to help you live longer.
  • Moms and dads think — and react — differently to newborn baby smells.
  • Clock and Cycle factors control circadian rhythm and protect your eyes as you age. 
  • Oleic acid produced in the brain helps regulate memory, learning, and mood; promotes neurogenesis; and increases cell proliferation.


EPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 29, 2022
Great Relationships Start with You & Hard Truths – Gary John Bishop : 932
01:06:20

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn that one of the major life upgrades you can make includes your relationships. 

Personal development expert Gary John Bishop doesn’t buy into mainstream notions of what makes a happy relationship. Not 50/50 effort, not compromise, not molding yourself into what your partner wants. It’s just you and some hard truths.

What this episode is not about;

  • Blame or providing communication tips
  • How to change or cope with your partner and personality types 
  • Healing past trauma or understanding fear of commitment 

Instead, you’ll get the ingredients to creating a real, lasting and profound connection with another human being.

“There's some, again, cold truths that you have to face and then really have to start to take on,” he says, “but in a way that it's not always going to go your way. You're not always going to get this thing flowing the way you would want it to go, but your job is to keep bringing yourself to this phenomenon in a way that's consistent with you, who you are, what you're about. And powerfully managing all that you might do to undermine it.”

Gary, the New York Times bestselling author of the Unfu*k book series, uses an “urban philosophy” approach that’s both simple and enlightening. In his latest book, “LOVE UNFU*kED Getting Your Relationship Sh!t Together,” he puts the focus on relationships. “The quality of your relationships dictates the quality of your life,” he says in “LOVE UNFU*kED.” 

This conversation gets right to the heart of what you can do to make changes that stick in all areas of your life.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 28, 2022
WetSpace, Crypto & Taking on Big Tech – Allie Rae : 931
01:09:43

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

You’ll be part of a candid conversation about choice and freedom. And, why it’s important to be able to make a living in your chosen line of work without restriction or judgment. That’s just part of being a better-performing human.

Guest Allie Rae, a wife, mother, retired nurse and Navy veteran, shares her unusual entrepreneurial journey within the adult sex entertainment industry. It may be a different topic than you expect on this show, but it’s a look at innovation opening up alternative ways of doing business outside restrictive Big Tech.

She’s CEO of a brand-new online adult platform called WetSpace. You may have heard about or know of the OnlyFans platform. WetSpace is similar, but not direct competition. 

Allie Rae saw a problem with payment systems and banking restrictions and set out to find a solution.

“At this point, this is no longer a hobby, it's a business for me,” Allie Says. “And as any business in any industry, you want to protect your business and provide stability and have long-term prosperity.”

We get into some cool topics:

  • Why Allie Rae created WetSpace;
  • How cryptocurrency fits into her plans;
  • The influence of Big Tech; and
  • How advocacy—not regulation—can guide the growth of the adult sex industry.


Today’s show looks at personal choice and freedom—both yours and other people’s. It challenges stigma, advocates for better systems of work, and supports creativity and business acumen.

it's important that we think about both sex, because that's one of those big things that nourishes us, and also think about what's going on in the world around us, that environment that controls your biology.

It matters that you’re able to choose what to do to and with your body, your energy, and your time. You get to choose to live your values—and so does everyone else. Even if you don’t agree. Being kind and respectful goes a long way in creating communities that allow you to be the highest performing human you want to be.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 26, 2022
Hacking Weight Loss Resistance – Interventions With Dave – Diane Closser : 930
00:43:58

IN THIS EPISODE OF THE HUMAN UPGRADE...

… Dave talks with Diane Closser about weight loss resistance. You’ll find out how unexpected and insidious factors–both internal and external–may be affecting your body systems. That dysregulation can cause your body to hold onto excess weight. 

Diane Closser knows a lot about chemicals. She’s a chemist by profession and works as a Certified Lubrication Specialist and Certified Reliability Leader at a Division of General Motors.

She also has a personal history of mold and heavy metal exposure, e.g., bought fixer-upper 1972 house, played with Mercury as a kid, worked as a wet bench chemist analyzing heavy metal production products, and worked in tire industry.

She’s been on a journey to wellness for several years that’s included a search for real health solutions. 

There have been some wins: In 2020, she became particularly sensitive to chemicals, perfume, and laundry detergent. She says that ozone therapy cured her of her sensitivity and reversed her autoimmunity. And some setbacks: Her health deteriorated when husband was diagnosed with a brain tumor in 2011.

She also had her house treated with Chlorine dioxide; did low-dose allergen therapy and low-dose immunotherapy; and completed chelation therapy. 

Through it all, she’s experienced a frustrating weight loss resistance. She says she’s “been on every diet and med known to man” since her teenage years. 

Now in her mid-50s, she’s looking forward to a retirement that includes sailing and bringing tap, jazz, and ballet classes to senior citizens around the country. She wants to improve her health and have the energy to make her plans a reality.

In this “Interventions With Dave” episode, Dave and Diane look at her health concerns through a new lens. They examine possible causes of her inability to shed excess weight and discuss actionable next steps. 

  • Calorie counting 
  • Eating too little 
  • Environmental toxins
  • Chemical sensitivities
  • Mold 
  • Ozone
  • Histamine
  • Mast cells
  • Metal toxicity and chelation therapy
  • Brain fog
  • Thyroid
  • Testosterone in females
  • Mycotoxins
  • Detox pathways
  • Collagen


Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

Listen to the Interventions With Dave series and don’t miss the “Links & Resources” section below for specific information. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 23, 2022
Top Tips from the Trainer of Superheroes – Magnus Lygdbäck : 929
00:48:06

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn how a trainer of superheroes and superstars combines core principles of fitness, nutrition, structure and balance.

Magnus Lygdbäck, a Swedish health and wellness expert, entrepreneur, and lifestyle coach, joins the show to discuss powering your life in ways that most benefit your health and energy.

For more than 20 years, he’s trained some of the world’s most recognizable actors, musicians, athletes, artists, and high-performance business entrepreneurs.

Musicians like pop stars Katy Perry, Dua Lipa, Harry Styles and Britney Spears. Actors like Gal Gadot for Wonder Woman 1984; Alicia Vikander, for Tomb Raider; Ben Affleck, for Justice League; and many more.

He designed Alexander Skarsgård’s incredible transformation for the lead role as a Viking Berserker in the brand new movie, The Northman

Even with his “celebrity trainer” title (which he doesn’t love), Magnus is quick to say, “It's not who you train, it's howyou train.”

His Magnus Method training philosophy embraces the “ethos of an athlete.” This all-inclusive approach to performance includes an athlete’s intensity and structure, while also maintaining balance and energy. Time-zone travel, long days of filming, rehearsals, and the constant demands on a celebrity performer’s time means examining all aspects of fueling, rest and recovery. The same applies to the everyday lives of mere mortals.

He encourages being open to learning new things and seeking out discomfort so you can grow. “Look at three things,” Magnus recommends. “One, what do I like to do? No. 2, what does my body need? No. 3, what do I want to master or get better at? That should create your weekly programming.”

You already know, and Magnus will remind you, that there are absolutely no life shortcuts to being the superhero of your own life.

In this conversation, you’ll find out how much time to spend on your workouts (not as much as you think). “What doesn’t happen in the first hour will not happen in the second,” he says frequently. Even for superheroes.

  • Learn more about Magnus Lygdbäck’s journey from hockey player to celebrity trainer.
  • Find out how you can improve your own performance on Magnus’s extensive YouTube channel.
  • Get Magnus’ superhero training programs, nutrition guides, coaching and a community of like-minded people with the Magnus Method app

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 22, 2022
How a Probiotic Strain Calms Your Body & Brain Stress – Kiran Krishnan, Ph.D. : 927
01:01:16

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SPECIAL OFFER FOR BULLETPROOF RADIO LISTENERS: Go to https://justthrivehealth.com. You’ll find their new line, Joot, and their new Just Calm probiotic for stress management and mood support. Just Calm features the proprietary “psychobiotic” strain BL 1714™ combined with brain-nourishing B vitamins. You’ll also find other products that tackle gut health and inflammationUse code ASPREY to get a 15% off discount.

IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn about a strain of probiotics called psychobiotics. This strain shows promising effects on stress relief, anxiety, mood, sleep and other important gut-brain axis connections.

Microbiologist Kiran Krishnan, Ph.D., explores the human microbiome and how it functions so you can have better gut health. He has an extensive research background in the fields of molecular medicine and microbiology. His particular expertise lies in gut commensal spore bacteria microbiology.

He’s been a guest on the show before to educate listeners about probiotics and the connections between your microbiome, inflammation and immune function. This time, he’s sharing exciting research about a probiotic strain that’s tackling the gut-brain axis, called Bifidobacterium longum 1714™.

Kiran says, “One really important message that I want people to really wrap their heads around and understand when we're talking about the gut-brain axis is, of course, the gut. A healthy gut is incredibly supportive to the brain. It supports the brain in a number of really important critical functions like recovery, for example, or production of serotonin and dopamine and all these important neurotransmitters, but on the other end of the spectrum, an unhealthy gut is not only not supportive, but it's arguably one of the most toxic things for the brain.”

Big topics covered in this episode include:

  • Basic mechanisms by which the gut microbiome can influence neurochemicals and brain inflammation
  • The gut-brain connection as it relates to stress coping and mental health
  • How cortisol and interleukin 6 drive stress response and inflammation in your whole body
  • Variables that can cause a breakdown or dysfunction in the psychobiome
  • Therapeutic interventions, including psychobiotics that can help correct gut-brain axis dysfunction


Kiran’s great at explaining the science so you clearly understand what the studies mean and can apply new knowledge to your own biology. He also partners with Just Thrive Health on product research and development.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 15, 2022
8 Natural Landscapes That Will Restore Your Energy – Emma Loewe : 926
00:55:20

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IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn how nature, human health, and climate activism interconnect. Emma Loewe, environmental journalist and senior sustainability editor at mindbodygreen, joins the show to share how nature can restore all aspects of your health. You’ll find out how you can reap the benefits of specific nature landscapes, wherever you live or roam.

You’ll come away from this episode with: 

  • Tips on how to combat stress, anxiety and burnout by being outdoors.
  • Actions you can take to conserve the landscapes you care about.
  • Mindset shifts that will change the way you think about the climate crisis.


In her new book, “Return to Nature: The New Science of How Natural Landscapes Restore Us,” she’s researched the ways eight distinct nature landscapes improve your physical, mental and spiritual health. 

  • Parks & Gardens
  • Oceans & Coasts
  • Mountains & Highlands
  • Forests & Trees
  • Ice & Snow
  • Deserts & Drylands
  • Rivers & Streams
  • Cities & Built Environments


Emma shares research-backed ways to explore nature now and protect it for the future, including SRT (stress-reduction theory). This theory says that humans are hardwired to relax while looking at environments that have extensive views, areas to retreat, and essential resources like shade and water.

Return to Nature” also offers:

  • Mindful exercises you can do in short or long chunks of time that allow you to fully experience nature when you’re in it. 
  • Additional resources about the eight natural landscapes Emma writes about.
  • Nearly 30 pages of research references! 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 12, 2022
How AI Transforms Your Body’s Biodata Into Real Health Solutions – Lola Priego : 925
00:58:35

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SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Go to https://get-base.com/DAVE. Use code DAVE to get 20% off your first purchase.

IN THIS EPISODE OF THE HUMAN UPGRADE™...

… you’re going to learn about the engineering it takes to build a health data app. You’ll find out how data science, mathematics and predictive analysis look at how biomarkers impact overall wellness. At Base, your own data, along with deep expertise from an advisory board of functional medicine doctors, inform the algorithms. This means you get a distinctly personalized prescription on how to manage your health concerns.

Guest Lola Priego, founder and CEO of Base, is an experienced software engineer and former medical student on a mission to help people better understand what is going on in their bodies. She possesses a unique combination of skills to do just that.

She studied medicine before transferring to engineering at the Technical University of Madrid and earned a master’s degree in Computer Science and Artificial Intelligence at the Illinois Institute of Technology. 

While struggling with her own health problems, she identified major pain points in the healthcare system like lack of access to personalized health data. She created Base to solve this issue with a data-driven approach that also provides actionable diet and lifestyle recommendations. Base gets to the root cause of health concerns through analyzing biodata like hormones, nutrition, and vitamin deficiencies to get to the core of why you feel “off.” 

Base provides testing options that usually are not available at a primary care doctor’s office (they’re often only offered by specialists). Convenience is built into the lab testing process. Base’s blood and saliva tests gets to the root of issues like stress, anxiety, fatigue, and brain fog. Here’s what Base and its accompanying app offer you so you can take control of your own biology and make meaningful life changes:

  • Regular testing tells you what’s going on with your biology.
  • Your own data informs recommendations on how to improve your diet, stress, energy, sleep, and sex drive.
  • You can track your results over time, get help from a team of online experts, and set specific health goals.


Because it’s your own health data, there are privacy issues at play you have to know about. Lola explains that security and privacy are built-in design features at Base.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 07, 2022
The Clear Eye Guide: How to Improve Your Vision Naturally – Claudia Muehlenweg : 924
01:24:31

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… natural vision expert Claudia Muehlenweg shares interesting knowledge and practical solutions about how you can take better care of your eyes and improve your vision. In this longer episode, 

  • You’ll discover ways you can improve your vision through natural methods that start with root causes in your body, including nervous system regulation.
  • You’ll explore bodywork, breathwork, rest, light and movement healing methods.
  • You’ll find out the essential Dos and Don’ts for good eyesight.
  • You’ll get practical suggestions for things you can do right now to offset the effects of screen time.
  • You’ll learn how you can keep your vision sharp throughout your life span.

 

After working to improve her own eyesight, Claudia founded Holistic Vision LLC to help others. Her work is based in the Bates Method. She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesight worse in the long term. 

She’s been teaching eyesight improvement since 2009. Her methods can improve presbyopia, myopia, astigmatism, hyperopia, strabismus, convergence insufficiency, and eye diseases such as cataracts, macular degeneration and glaucoma. She also helps people restore clarity after corrective surgeries like LASIK have worn off.

Her experience as a yoga teacher brings together complementary practices like myofascial release, breathwork and bodywork that greatly influence holistic vision care and natural vision healing methods.

SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS!

Step 1: FREE 5 Day Training “See Better in Just 5 Days” April 11-15, 2022. Click here to register.

Step 2: FREE “See Clearly Without Glasses or Surgery!” live workshops. Choose one date: April 18, 20 or 22, 2022. Click here to register.

Step 3: “Naturally Clear Vision” 10-week online holistic vision improvement program. Click here to register-waitlist only.

Just want a freebie? “10 Habits for Happy, Healthy Eyes.” Get the guide here.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 05, 2022
Upgrade Spotlight: Improve Your Sleep With a Cooler Body Temp – ChiliSleep : 923
00:29:37

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Be Cool, Get Deeper Sleep: Check out the Dock Pro Sleep System at https://www.chilisleep.com/discount/HUMANUPGRADE20. Use code HUMANUPGRADE20 to save 20%.

IN THIS EPISODE OF THE HUMAN UPGRADE...

…you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. 

You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. 

Introducing ChiliSleep! During this Upgrade Spotlight, you’re going to learn about the physical and mental health benefits of cool sleep and how to hack your sleep with new bed technology.

You already know about the physical and psychological effects of not getting good sleep. Whether you’re dangerously sleep-deprived or can’t stop waking up in the middle of the night, struggling to get enough sleep over time can have devastating impacts on your body and mind.

Poor sleep increases a person’s risk of developing serious medical conditions, and not getting enough deep sleep increases the chance of high blood pressure; heart attack and stroke; Dementia and Alzheimer’s disease; and Type 2 Diabetes. 

Tara Youngblood founded ChiliSleep so people could get the coolest sleep ever. Water-based cooling helps your body settle into a just-right temperature that’s just right for you

Your core body temperature should naturally drop every night, but for lots of people for lots of reasons it doesn't. Here are a few of the good things that happen when you regulate your sleep temperature:

  • Cooler temperatures cue your brain to release melatonin and help you fall asleep faster. 
  • Sleeping at colder temperatures improves deep sleep and increases muscle recovery.
  • Muscle repair and growth occur during deep sleep and REM sleep stages due to the natural release of growth hormones.


Tara creates technologies and apps to help you recover your sleep and your energy. She’s a trained scientist with degrees in Science and Physics who also studied traditional Chinese medicine, Ayurvedic practices, neuroscience, and psychology.

She focuses on how your physical body can get better sleep and the important essential link between sleep and mental health.

Get Dangerous with Dave's new Remineralized Coffee: https://dangercoffee.com

Join the 8th Annual Biohacking Conference: September 2022! https://biohackingconference.com

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Apr 02, 2022
Home Lab Testing 101: Your Guide to Great Results – Dolce Conde : 922
00:48:56

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’re going to get a step-by-step guide to taking accurate labs at home. You’ll learn how to use home test kits effectively to get high-quality results.

At-home test kits got more popular in the past few years as people wanted to know more about their personal health data. Knowing your data gives you the power to control your own biology.

Some of the biggest value drivers of at-home labs include: Convenience, performance specificity, and being proactive rather than reactive about your symptoms.

Dolce Conde co-founded Knowing Labs to support a growing community of people who want to be proactive about their health.

Knowing Labs offers reliable laboratory testing directly to consumers in the convenience and privacy of their homes. The kinds of test kits available at Knowing Labs include panels for vitamin D, inflammation, sleep & stress, weight & energy, male and female hormones and wellness, and many more.

If you want to use home test kits to find out more about your own data and upgrade your health, here are a few essentials to know:

It’s important to choose a certified lab.

  • Knowing Labs is a High Complexity CLIA Certified Laboratory in the State of Texas.
  • CLIA means the Clinical Laboratory Improvement Amendments that regulate laboratory testing.
  • All Knowing Labs testing is done in-house so they have total control over the quality and performance of the services.

It’s important to understand the type of at-home test kit you have and how to collect accurate samples. 

  • This could be saliva, blood or urine, depending on the kit you choose. 
  • For blood samples, this could mean a spot, pipette or home phlebotomist visit.
  • Conde talks about some best practices and troubleshooting tips.

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Mar 31, 2022
How to Ditch Diet Dogma and Simplify Superfoods – Max Lugavere : 921
00:59:53

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…you’ll take a deep dive into the science of healthy eating so that you can know how to leverage food for high energy and performance.

Health and science journalist Max Lugavere studies and writes about ways that food and movement fuel you. And allow you some balance and freedom in your choices.

He joins the show to round out a body of work that includes his best-selling “Genius Foods,” “The Genius Life” and now his latest to complete the trio: “GENIUS KITCHEN: Over 100 Easy and Delicious Recipes to Make Your Brain Sharp, Body Strong, and Taste Buds Happy.

“It's a kitchen and wellness guide,” Max explains. “I didn't want to just make a book of recipes. That would've been too easy. I wanted to make something that was going to stand the test of time and serve as a resource for people."

His work was inspired by his mom’s diagnosis with a rare form of dementia in her 50s. He dedicated himself to her care and also began researching how to prevent cognitive decline through nutrition. 

“Though I began to cook when my mother could no longer cook herself, I realized that culinary literacy (like health literacy) had become yet another aspect of life that we had outsourced,” Max says in “Genius Kitchen.” I became passionate about creating healthy food that is delicious and easy to make."

There’s a multi-billion dollar diet industry that makes nutrition confusing and complex. This conversation gets into the value of simple food, how to find your own food philosophy and why Max rejects diet dogma. So this is the episode for you to:

-Learn science-backed tactics to improve digestion, increase nutrient extraction and stop common digestive complaints. 

-Get practical food lists and cooking methods for easy, nutritious meals that work for your performance goals and everyday life.

-Find out how to eat like a “genius” with these topics:

  • The upside & downside of plants
  • Protein quality & muscle maintenance
  • Organ meats
  • Fantastic fats & ominous oils
  • The shudder of sugar
  • Essential fatty acids
  • Calcium & the debate about dairy
  • And more!


More about Max: 

Max gets his curious on hosting The Genius Life podcast. He appears regularly on the Dr. Oz Show, the Rachael Ray Show, and The Doctors. He’s been featured on NBC Nightly News, The Today Show, and in The New York Times and People Magazine and contributed to Medscape, Vice, Fast Company, CNN, and the Daily Beast. He’s an international speaker who’s presented at events like South by Southwest, TEDx, the New York Academy of Sciences, and the Biohacker Summit in Stockholm, Sweden.

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Mar 29, 2022
Mini-Episode: Cool Facts Friday #21
00:10:52

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Strategic eating fills micronutrient gaps. 
  • Use probiotics to turn down your allergies.
  • Your DNA determines your coffee preferences.
  • Got 3 seconds a day? Use it to strength train.
  • Time your meals to control blood sugar and melatonin. 

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Mar 25, 2022
Juicing Done Right for You and the Environment – Junaid Kalmadi – #920 : 920
00:53:18

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IN THIS EPISODE OF THE HUMAN UPGRADE...

Did you know?

  • Less than 9% of people meet a daily vegetable intake that’s best for their body.
  • Soil has up to 50% less nutrition than 1945
  • And up to 40% of produce gets wasted on farms. 


Green juicing—done the right way—can upgrade all of those things. Junaid Kalmadi joins the show to talk about soil degradation, farming practices, and produce waste. He explains that it’s possible to do juicing safely and in ways that don’t break the planet even more.

Junaid (with Dave as an advisor) founded Farmers Juice, a keto-friendly and functional green juice line that uses a cold-pressed process. 

“You separate the pulp from the juice, and you get this end product of this incredibly high nutrient-dense jolt of vitamins, enzymes, phytochemicals that give you this tangible positive effect within your biology, within your mood, within your own like mental state to perform your best,” Junaid says.

It takes 1.5 pounds of produce (no kale!)  to make one bottle of organic Farmers Juice. The juices also contain adaptogens, antioxidants, and mushrooms to boost focus, calm, and athletic performance. 

Along with finding out what’s in the juice, you’ll learn about nutrigenomics and how food information tells your body what to do. You’ll also learn how phytonutrients act as your genetic control system and keep you healthy. 

Food and nutrients directly, immediately, and specifically interact with our genes, controlling moment-to-moment changes in your physiology and biochemistry.

For juicing 101, particularly ingredients and processing, take a listen to: Why Dave Asprey Changed His Mind About Juicing – #802.

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Mar 24, 2022
How Intermittent Fasting Works for Women – Cynthia Thurlow, NP : 919
01:06:42

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IN THIS EPISODE OF THE HUMAN UPGRADE..

  • You’ll learn about the science-based benefits of intermittent fasting for women, especially during midlife.
  • You’ll get details about intermittent fasting advantages for women like how to gain hormonal stability and metabolic health, and how to improve your energy.
  • You’ll get practical intermittent fasting how-tos, nutritional guidelines, carb cycling recommendations, food lists, and recipes to try during your feeding window.


Cynthia Thurlow joins the show to talk about how intermittent fasting can help women change their body, metabolic system and brain function. She has tips for women at all stages: from active menstrual cycles to perimenopause to menopause.

Cynthia is a Johns Hopkins-trained nurse practitioner and functional nutritionist founded and serves as CEO of Everyday Wellness Project. She holds a Master of Science degree in Nursing and Functional Nutrition certifications with advanced trainings in Endocrinology and Gastroenterology. Her career in healthcare includes nearly 20 years of emergency medicine and cardiology experience. She brings a broad perspective when working with women to improve the state of their health. 

“I really start from a foundational level talking to women about fasting,” Cynthia says. “It's really honoring our own unique physiology. It's leaning into that menstrual cycle. It's leaning into the lifestyle piece that so much of us forget to talk about with our patients, our sleep quality, stress management, anti-inflammatory nutrition, our exercise quality, our connection with nature, all of which are critically important.”

She also addresses diet dogma that frustratingly persists, even with established and emerging science about the benefits of intermittent fasting.

She tackles this outdated dogma (and a lot more!) in her new book, “Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.”

“[Intermittent fasting] restores our intrinsic rhythms, burns fat, regenerates our health right down to the cellular level, and stabilizes our hormones,” Cynthia says in her book. “In turn, we are less likely to develop obesity, diabetes, vascular diseases, and autoimmune disorders.”

At the end of this conversation, you’ll have the tools to decide if intermittent fasting is the right choice for the state of your own health. 

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Mar 22, 2022
Hacking Thyroid, Autoimmunity & Aging – Interventions With Dave – Michael Ford : 918
00:44:22

IN THIS EPISODE OF THE HUMAN UPGRADE...

… Dave talks with Michael Ford about low thyroid function, autoimmunity and aging concerns.

At 70, Michael has been biohacking for over three years, takes a consistent supplement regimen, incorporates intermittent fasting, and does frequent microbiome and blood checks.

He takes only one medication for low thyroid function and is looking for alternative ways to manage it. He suspects he has an autoimmunity issue and would like to explore that more.

In the past few years, Michael has seen the health of colleagues, friends and elderly family members decline considerably. He’s concerned about aging and wants direction on how to live to be fully functional at 140 (or more!). With so much health information available to the general publicmuch of it contradictory, Michael asks Dave for insight and input.

In this “Interventions With Dave” episode, Dave also talks with Michael about:

  • Supplements
  • Testosterone
  • Cortisol-causing excess weight
  • Visceral fat
  • Healthy fats
  • Red light benefits
  • Dental health
  • Breathing & mouth taping
  • Improving brain blood flow


They look at his health concerns through a new lens and discuss actionable next steps. Don’t miss the “Links & Resources” section below for specific information. 

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

Listen to the Interventions With Dave series:

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Mar 19, 2022
Analyze Your Gut to Fix Your Health: Here’s How – Naveen Jain : 917
01:01:11

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IN THIS EPISODE OF THE HUMAN UPGRADE...

Dave’s good friend, entrepreneur and philanthropist Naveen Jain, joins the show to talk about the future of human biology and wellness. What’s new right now, what’s emerging, and what’s on the horizon. He’s been a guest several times before (see the Links & Resources section below!) and there’s always something new to learn when he and Dave get together. This time, they explore testing the human biome.

Naveen’s a guy with enormous vision who builds companies and partners with others to tackle and solve the gnarliest problems affecting the health of our people and planet. 

He always encourages curiosity and big thinking: ““Curiosity is what drives the humanity forward. The day you stop being curious is the day you die.”

In this discussion, you’re going to learn ways innovation can change human biology from a micro and macro level—from your cellular health to broader planetary issues. You’ll also learn how you can test to find out what’s happening within your gut, cells and immune system. With that knowledge and personalized recommendations, you’ll have the power to change your health for the better.

Naveen founded, Viome, the worlds’ largest database of microbial gene expression. Its AI-driven personalized therapeutics platform and applications identifies predictive markers of chronic diseases. Viome does this by using a functional analysis of microbial, mitochondrial and human gene expression. “We actually see everything,” Naveen explains. “As long as an organism is alive, we see it. So whether it is a bacteria, virus, fungus, mold, it doesn't matter. We see everything.”

In particular, Viome’s Health Intelligence™ Test looks at:

  • gut microbiome
  • mitochondrial function
  • immune cell function
  • cellular health
  • stress response
  • biological age


The more data can inform what’s happening inside of you, the more resources you’ll have to improve your health.

More about Naveen Jain:

Naveen wrote the award-winning book, Moonshots: Creating a World of Abundance and created Mindvalley, Masterclass programs. He’s behind XPrize, a global future positive movement and is on the board of Singularity University

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Mar 17, 2022
How to Treat Body-Based Anxiety – Dr. Ellen Vora : 916
00:49:43

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IN THIS EPISODE OF THE HUMAN UPGRADE...

 … Ellen Vora, M.D., takes a functional medicine approach to mental health that considers the whole person and addresses imbalance at the root. 

She’s a Yale and Columbia University educated holistic psychiatrist board-certified in psychiatry and integrative holistic medicine. She’s also an acupuncturist and yoga teacher.

In her new book, “The Anatomy of Anxiety: Understanding and Overcoming the Body's Fear Response,” she takes on anxiety, which hits more than 40 million people in any given year. The pandemic drove that number up even more. Even if math isn’t your strong suit, you can understand these numbers:

  • An estimated one out of every nine people, or 800 million people, suffer from a mental health disorder, the most common of which is anxiety. 
  • Up to 33.7 percent of Americans are affected by an anxiety disorder in their lifetime. 


Conventional medicine tends to view anxiety as a “neck up” problem of brain chemistry and psychology. Dr. Vora disagrees. She suggests that various physiologic inputs influence anxiety symptoms. 

“What we've been indoctrinated with is this idea that our mental health is genetically determined chemical imbalance,” Dr. Vora says. “There's some validity to that, although I think, for the most part, any chemical imbalance is often a downstream effect of a state of imbalance happening elsewhere in the physical body.”

In this episode, you’ll learn:

  • the difference between avoidable, purposeful, false and true anxiety;
  • simple strategies for tuning into “true” anxiety and using its benefits;
  • how your body may be physiologically out of balance (immunity, gut health, inflammation);
  • how “hanxiety” means that blood sugar is affecting your anxiety; 
  • actionable lifestyle factors to bring yourself back into balance; 
  • how to manage medication withdrawl; and 
  • how to reframe your understanding of, and relationship with, anxiety.


Dr. Vora also confronts what she calls techxiety. This can include a boundaryless workplace, how the posture of screen use signals your body for anxiety, and, of course, social media. Research shows social media is associated with higher rates of anxiety and depression. Just 20 minutes of Facebook can impact mood.

So much of how you live your life as an adult profoundly impacts how your mental health manifests, and that's the part you can control.

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Mar 15, 2022
Hacking Inflammation – Interventions With Dave – Cindy Fraley-Hunter : 915
00:47:55

IN THIS EPISODE OF THE HUMAN UPGRADE...

… Dave talks with Cindy Fraley-Hunter about system-level inflammation and her fear of having an early heart attack like her father because they have such similar genes.

Cindy thought she was healthy until after the birth of her daughter at 42. She was constantly tired. Her physician told her that was just to be expected because she was a geriatric pregnancy. That unhelpful advice ignored her body functioning and lacked actionable solutions.

She then survived a case of MRSA and received Hashimoto’s and rheumatoid arthritis diagnosis. She continued to have high cholesterol and a high CAD calcium heart score. She’s scared her life will be cut short.

Feeling like conventional medicine is failing her, Cindy has turned to supplements instead of prescription drugs. She says she’s “embracing biohacking to save my life.”

In this “Interventions With Dave” episode, Dave walks Cindy through her most recent labs and other test results. They look at her health concerns through a new lens and discuss actionable next steps. Don’t miss the “Links & Resources” section of episode web page #915 for specific information.

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

Listen to the Interventions With Dave series:


Coffee & Bohacking with Dave Asprey

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Mar 11, 2022
Synthetic Biology to Become a Major Economic Driver, Part 2 – Amy Webb : 914
01:15:30

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll get a look at synthetic biology (SYNBIO) through the lens of quantitative futurist Amy Webb in Part 2 of a special two-part episode. The Part 1 episode #913 explores the scientific perspective with microbiologist and geneticist Andrew Hessel.

Amy and Andrew recently authored, “The Genesis Machine: Our Quest to Rewrite Life in the Age of Synthetic Biology.” SYNBIO is the promising and controversial technology platform that combines biology and artificial intelligence. Amy investigates what SYNBIO means for people, commerce and the planet. 

“This is a book about science,” Amy describes, “but I did not want to write a science book. This is also a business book. It's an understanding-your-own-body book.”

She’s a futurist who works with data and does predictive modeling. Her academic background includes game theory and economics

Amy founded the Future Today Institute to help companies understand the forces that will shape their futures. She’s a professor of strategic foresight at the NYU Stern School of Business and a Visiting Fellow at Oxford University’s Säid School of Business. She writes extensively about biotechnology, artificial intelligence, technology policy, and business strategy.

“This emerging field of science—synthetic biology—promises to reveal how life is created and how it can be recreated, for many varied purposes, as explained in “The Genesis Machine:”

  • to help us heal without prescription medications, 
  • to grow meat without harvesting animals, and 
  • to engineer our families when nature fails us.


With SYNBO developments come a slew of considerations about how to manage it responsibly.

“For the most part, in the US, the regulation is on the end product,” Amy says. “Nobody wants to regulate the process, because we don't want to hamper innovation. However, it does start to raise some gnarly questions when we're talking about alternative uses or different uses for some of these technologies, or cross-border use.”

“There's some alignment globally on what's called germline editing, which is when you edit the genome to make it heritable. So whatever that is passes on. At the moment, just about 190 countries have aligned [to agree] that they don't want that to happen. But outside of that, there's a lot of confusion.”

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Mar 10, 2022
Controlling Genetic Destiny with Synthetic Biology, Part 1 – Andrew Hessel : 913
01:22:39

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn about the implications of synthetic biology in Part 1 of a special two-part episode.

Andrew Hessel and Amy Webb recently authored, “The Genesis Machine: Our Quest to Rewrite Life in the Age of Synthetic Biology.” This Part 1 episode gets into the scientific perspective with Andrew. Part 2 on episode #914 explores the futurist perspective with Amy.

Ask yourself, if you could edit your genes—to fix infertility, diabetes or even depression—would you do it? That’s the premise, and the promise, of synthetic biology. And a reality you’ll have to wrestle with. To make these decisions intelligently requires a deeper—and urgent—understanding of what’s happening in science.

Right now, scientists are rewriting the rules of our reality. They can use computers to gain access to the cells of any living organism and write new, potentially better, biological code. 

Andrew—a microbiologist and geneticist—works on the leading edge of genomics and bioinformatics. He’s been immersed in the world of synthetic biology for years and joins the show to explain new advancements.

As a scientist, communicator, and investor, he explores the future of biology and biotechnology. He co-founded the Center of Excellence for Engineering Biology and the Genome Project-write. The Genome Project-write is an international scientific effort that designs and builds large genomes, including the human genome. 

As we embrace that life no longer will be a game of chance, it will be the result of design, selection and choice, morechoices have to be made. Decisions like who gets to program life, create new life forms, and even bring former life back from extinction?

“The Genesis Machine" is a book about science, but it's not written for scientists, Andrew says. “It's about some amazing people and stories and we've got some fun scenarios that help you think about where some of this stuff is going. But really, this is a technology that we're all building day by day.”

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Mar 09, 2022
Keto Gets an Upgrade – Dr. Steven Gundry : 912
01:29:57

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SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS:

  • Pre-order your copy of “Unlocking the Keto Code” before March 7, 2022, and receive your choice of “The Energy Paradox,” or “The Plant Paradox,” or an early release chapter of “Unlocking the Keto Code,” and an exclusive sneak peek digital recipe guide! Go to https://drgundry.com for details. 
  • Get 30% off products at https://gundrymd.com. Use code DAVE30 at checkout.


IN THIS EPISODE OF THE HUMAN UPGRADE...

… Steven Gundry, M.D., introduces you to the biological mechanism that makes keto diets so successful: a cellular process known as “mitochondrial uncoupling.” 

He’s spent the last two decades studying the microbiome and uses diet and nutrition as a key form of treatment for people who want to improve their body health and performance. You may already know Dr. Gundry from his bestselling books like: “The Plant Paradox,” (lectins!) “The Longevity Paradox” and “The Energy Paradox.” 

This discussion gets right into new science that’s overhauling what you think you know about a keto diet. In his newest book, “Unlocking the Keto Code: The Revolutionary New Science of Keto That Offers More Benefits Without Deprivation,” Dr. Gundry debunks common myths about keto and explains:

  • How ketosis actually works,
  • What’s going on with ketones, and 
  • What your mitochondria has to do with all of this.


You don’t have to restrict all carbs to reap the benefits of ketosis; you simply have to “unlock” mitochondrial uncoupling, Dr. Gundry explains.

He shares eight “keys” that unlock the keto code. You’ll get real food examples of how to ignite this process without the monotonous, limiting, high-fat diet.

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Mar 04, 2022
Goal Get It! How to Reflect, Dream and Focus Your Way to Success – Payal Kadakia : 911
00:52:56

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IN THIS EPISODE OF THE HUMAN UPGRADE...

Entrepreneur, investor and artist Payal Kadakia brings a fresh perspective to your understanding of goals. She knows a lot about setting big goals and reaching them.

She founded ClassPass and over a decade grew it to become the leading fitness and wellness membership service valued at over $1 billion. Mindbody acquired ClassPass in October 2021. At that time, members had logged more than 100 million hours of workouts across 30,000 partner studios in over 30 countries. 

We’re going to talk today about how you can upgrade your own goal setting with “LIFEPASS: Drop Your Limits, Rise to Your Potential.” 

Using her company Class Pass as an example, Payal highlights the importance of knowing your strengths, your unique talents,  who you are, and investing in the right people and mentors to show you the way. 

Payal gives insight on how to set boundaries in service to your priorities, and how every minute of the day belongs to YOU, not anyone else. This means you don’t have to hold onto any guilt about doing what's right for you.

You’re more likely to reach your goals when you get to let go of the pressure to achieve a traditional kind of success and instead fuel your life with purpose. And when you focus on a life of creativity, you get to live the life you most want to live.

The 4-step LifePass Method combines intuition, pie-in-the-sky dreams, micro focus, and macro goals.

  • Reflect: Where have you been?
  • Dream: Where do you want to go?
  • Focus: What are your priorities?
  • Set Goals: What’s the plan?


Payal, an Operations Research and Economics graduate from MIT, been featured in most major news outlets; listed as Fast Company’s 100 Most Creative People; and named to Fortune's 40 under 40 list. 

She formerly worked as a consultant at global management consulting firm Bain & Company and was part of Warner Music Group’s Digital Strategy and Business Development Group. 

She’s also got an extraordinary artistic side. She founded The Sa Dance Company in 2008 and serves as Artistic Director.

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Mar 01, 2022
Mini-Episode: Cool Facts Friday #20
00:08:47

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Breathing coordinates neuronal activity—even without smell
  • Mindful breathing in virtual reality can control real pain
  • Circadian cycle affects immune cells and Alzheimer’s plaques
  • Brain refresh lags when processing visual stimuli
  • Medical repression in the days of Ivan the Terrible

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Feb 25, 2022
Happiness Starts with Your Brain Type – Dr. Daniel Amen : 910
01:21:06

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IN THIS EPISODE OF THE HUMAN UPGRADE...

“Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that. 

He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness.

“I wanted to spend my time and energy and research on happiness because, ultimately... happiness is a moral obligation because of how you impact other people,” Dr. Amen says. “The big central point [is] the brain is the organ of happiness, and if your brain is not healthy, you are not likely to be happy.”

What makes you happy? The answer lies in knowing your specific brain type and how it’s being influenced by seven specific chemicals.

Happiness originates in distinct brain regions: pleasure in the orbitofrontal cortex; motivation and habit formation in the basal ganglia; and mood and cognitive flexibility in the brain stem.

You may be one or a combination of these five primary brain types: (take this brain assessment to find out yours)

Balanced: you have a very healthy brain

Spontaneous: you have low dopamine

Persistent: you’re often worried, rigid, and inflexible

Sensitive: you need other people and isolation is hard

Cautious: your GABA levels are low

Learn more about brain types and what actually boosts your happiness according to neuroscience in Dr. Amen’s book, "You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type.”

“Happiness comes from moving your life forward toward your life goals with meaning and purpose, based on your values, despite whatever obstacles are in your way,” Dr. Amen says. “A happy life doesn’t focus on the past with regret or look to the future with fear.”  

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Feb 25, 2022
New Developments in Stem Cell Treatments – Dr. Harry Adelson & Dr. Amy B. Killen : 909
00:55:49

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IN THIS EPISODE OF THE HUMAN UPGRADE...

 …you’re going to find out about Dave’s recent stem cell procedure and the newest technology stem cell medicine happening at Docere Clinics in Park City, Utah.

Dr. Harry Adelson was one of the earliest adopters of the use of stem cells for the treatment of chronic musculoskeletal pain. His practice has offered 100% Regenerative Injection Therapy since 2002 and 100% stem cell therapy since 2010. He’s performed more than 6,000 stem cell procedures and invented the Full Body Stem Cell Makeover®, the most comprehensive stem cell upgrade currently available. 

His colleague, Dr. Amy B. Killen performs anti-aging and regenerative medical treatments. She’s fellowship trained in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine. She’s also done extensive additional training in aesthetics, platelet rich plasma and stem cells, hair restoration, bio-identical hormones, nutrition, fitness and sexual health.

Drs. Adelson and Killen performed Dave’s original Full Body Stem Cell Makeover®, which used Dave's own stem cells from his fat and bone marrow, as well as extracellular vesicles. This episode gets into new developments in stem cell treatments, like the advent of VSEL (very small embryonic-like stem cells) technology. 

Stem cells therapy may be right for you if you’re interested in:

  • Better skin
  • Increased sexual performance
  • Decreased pain
  • Improved functional body movement
  • Preventive aging treatment

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Feb 22, 2022
Hacking the Gut Microbiome – Interventions With Dave – Tim Waters : 908
00:48:31

IN THIS EPISODE OF THE HUMAN UPGRADE...

… Dave talks with Tim Waters about ways to improve the health of his gut microbiome. 

A former wrestler, Tim spent years cutting weight. He experienced gall stones and eventually had his gall bladder removed 20 years ago. That led to long-term use of proton pump inhibitor pharmaceutical. Now over 50, Tim wants to wean off the pharmaceutical and heal his gut. He’s made some progress on his own but has some complicating factors at play.

Here are a few things you'll learn in this “Interventions with Dave” episode:

  • What causes low stomach acid
  • The difference between a proton pump inhibitor and an H2 blocker
  • How certain foods influence gastric reflux
  • How to manipulate your gut pH (acid and heat)
  • The role enzymes play in digestion
  • The importance of bile
  • The benefits of butyric acid
  • How to get your good gut bacteria working
  • How to check your methylation
  • Why tracking your blood pressure regularly is a great idea


This conversation covers a lot of gut ground! Don’t miss Dave’s intervention recommendations in the “Links & Resources” section of the episode webpage: https://daveasprey.com/intervention-tim-waters-908/

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

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Feb 19, 2022
Form, Function & How to Fix Your Feet – Peter Francis, Ph.D. : 907
00:57:27

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IN THIS EPISODE OF THE HUMAN UPGRADE...

…whether you’re hiking, climbing, working or playing, your feet ground you. Except when they don’t. Shoes don’t always match up to the function of your life. You can end up with pain and misalignment throughout your body when your feet are encased in shoes that don’t support your body’s natural biomechanics.

Feet, for all their variety in shape and size, get the award for amazing. Your feet literally form the center of your body’s whole system of movement. Did you know these facts about the human foot?

  • 26 bones, nearly 30 muscles and thousands of nerve endings
  • 33 articulations (each with six degrees of freedom of motion) 
  • Humans began running about 2 million years ago to be able to hunt


“If the foot moves normally, then the muscles start to work and so on and so on,” says Peter Francis, Ph.D. “It’s really just about allowing your foot to move as nature intended.”

Peter joins the show from the Carlow Institute of Technology in Carlow, Ireland. There, he lectures in sport and health science and researches how modern environments effect human health and performance. 

With degrees in Sport and Exercise Science and Physical Therapy, and a PhD in Exercise Science, he’s written more than two dozen peer-reviewed journal articles and led numerous research projects. He’s also worked with teams and individuals at amateur, European and Olympic level. 

He knows feet! And, he’s got a lot to share about how feet influence the way your body moves. A runner himself, Peter studies the role of foot development with and without shoes. He then figures out what that means for movement skills and injury risk.

Your feet are by their form and function incredibly sensory. When you block sensory information from your feet, you have trouble maintaining stability and balance.

You may think that your shoes help support your feet, but the opposite proves true. Shoes strip your natural movement and make your feet weak.

Your shoes, not your feet, are the problem.

In this conversation, you’ll learn what footwear works best for you and your kids and the importance of variability and fun in your movements. Start with Vivobarefoot barefoot-style shoes to reap the benefits of living life barefoot (or close to it).

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Feb 18, 2022
How Uric Acid Disrupts Your Metabolic Heath – Dr. David Perlmutter : 906
01:18:00

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… guest Dr. David Perlmutter explains how he’s an expert in dropping acid, but not in the way you might think. A regular contributor to groundbreaking science, he’s back on the show to talk about why you should be paying attention to your uric acid levels. 

Dr. Perlmutter is a neurologist and five-time New York Times bestselling author. His books include “Brain Wash,” “Grain Brain” and  “Brain Maker.” He’s recognized internationally as a leader in the field of nutritional influences in neurological disorders. Now, he’s turning his attention to how uric acid threatens your metabolic health.

Uric acid is a waste product of metabolism, and its levels are a key health marker and indicator of chronic degenerative diseases. When uric acid levels rise, they tell your body to store fat, which messes with your metabolism and poses a danger to your health.

Alcohol, purines (breakdown product of DNA and RNA in foods) and fructose (the kind of sugar found in processed foods) are the three main sources of uric acid. Since the days of our primate ancestors, we’ve lost the ability to break down uricase, so what we choose to consume makes a big difference.

“If we can emulate those signals to our DNA and our physiology that have evolved to keep us healthy,” Dr. Perlmutter says, “we're going a long way to offsetting these incredibly powerful metabolic disruptions that are paving the way for the biggest cause of disease on our planet.”

His newest book, “Drop Acid: The Surprising New Science of Uric Acid—The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health,” includes ways to measure, control and track your uric acid levels and key strategies to manage them. You’ll find out the top five foods that raise uric acid (hint: fructose earns the No. 1 spot). You’ll also find out the five important supplements to take to lower your uric acid levels back into a healthy range.

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Feb 15, 2022
Longevity Strategies To Use Right Now – Tony Robbins & Peter Diamandis, M.D. : 905
01:07:53

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IN THIS EPISODE OF THE HUMAN UPGRADE...

…Tony Robbins and Peter Diamandis, M.D., distill the knowledge, expertise and life’s work of more than 100 doctors, scientists, and Nobel Laureates. The world’s top experts in medicine, technology, and science show you what’s available right now. This means you can gain access to the tools that turn back your biological clock.

Tony is an entrepreneur, best-selling author, philanthropist, and the nation’s No. 1 life and business strategist.

Peter accelerates breakthroughs in products, companies, and industries to solve some of the world's greatest challenges. He’s a Harvard Medical School-trained doctor; founder and executive chairman of the XPRIZE Foundation; and executive founder of Singularity University.

I wanted to have them on the show together to talk about what’s new and next level in biohacking and the incredible advances happening in health technology. They teamed up to write the new book: “Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love.

The book lays out advancements in precision and regenerative medicine so you can increase your energy, improve your immune system, and extend the length and quality of your life.

Tony’s own personal health issues and use of stem cells led him into the topics in this book. In less than a year using many of the advances he writes about, Tony reduced his biological age from 62 to 51.

Coming in at nearly 700 pages, “Life Force” guides you through sections of easy-to-digest information and practical tips.

  • The Life Force Revolution (how to make yourself the CEO of your own health)
  • Heroes of the Regenerative Medicine Revolution (technologies changing every concept we think we understand about medicine)
  • What You Can Do Now (ways to expand your physical and emotional energy)
  • Tackling The Top 6 Killers (heart disease, stroke, cancer, inflammation and autoimmune disease, diabetes and obesity, Alzheimer’s disease)
  • Longevity, Mindset & Fulfillment (exponential technologies driving longevity like genome sequencing, storage, computation and communications) 

 

Through this compilation by Tony, Peter and Robert Hariri, M.D., Ph.D., you’ll find out about powerful resources for healing, transformation and regeneration of the human body. You’ll accelerate your learning, dial up your performance and put into motion innovative ways you can live a longer life.

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Feb 15, 2022
Hacking Menopausal Weight Gain – Interventions With Dave – Cheryl Fraser, Ph.D. : 904
00:46:57

IN THIS EPISODE OF THE HUMAN UPGRADE...

 … Dave talks with Cheryl Fraser, Ph.D., about menopausal weight gain and ways to manage changing hormones and metabolic mayhem.

 As a Buddhist psychologist, sex therapist, author and speaker, Cheryl’s sharp, frank, and fearless. She’s also deeply frustrated about gaining weight during menopause that just won’t budge. She’s put on 15 pounds in the past five years. Despite doing various eating programs and being physically active, she continues to struggle with weight loss and metabolic stability.

In this “Interventions with Dave” episode, you’ll learn about:

  • Learned helplessness
  • Low DHEA 
  • Testosterone’s role in female health
  • Adrenal hormones
  • Managing cortisol
  • Keto cycling
  • Thyroid function influences energy
  • Thyroid supplements 
  • Meats high in Omega-6 
  • Biohacks for lymphatic drainage & detox
  • Upgraded fitness hacks
  • Red and infrared light effects on blood flow and nitric oxide
  • Recovery benefits

 

Keto Tracking: Get Your Mojo On With All Things Keto – Dorian Greenow – #824

CAROL AI Bike Fitness: Shorten Your Cardio Time Even More with REHIT – Ulrich Dempfle – #834

Lighting for Your Biology and Environment: https://truedark.com, use code DAVE to get 15% off 

“Fast This Way: Burn Fat, Heal Inflammation and Eat Like the High Performing Human You Were Meant To Be” 

Fasting Challenge

“Super Human: The Bulletproof Plan to Age Backward and Maybe Even Live Forever”

Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

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Feb 11, 2022
High Performance Requires Radical Adaptability – Keith Ferrazzi : 902
01:08:39

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IN THIS EPISODE OF THE HUMAN UPGRADE... 

…entrepreneur, biohacker and leadership expert Keith Ferrazzi says going with the flow of change, or even leaning into it, isn’t nearly enough. You’ve got to go for radical adaptability. He’s here to explain what it means and how you can use it for yourself and your business. 

“The essence of radical adaptability is that it is predictive, proactive, and progressive, very unlike the typical response to change, which is inherently reactive and conformist,” he says.

Keith, an expert in relational and collaborative sciences, founded Ferrazzi Greenlight, a research institute that focuses on the impacts of behavioral science on business. He coaches Fortune 100 company leaders and executive teams. In that coaching, he teaches people how they can change their organizational behaviors to increase growth and value.

“If you're in business, if you work in an organization or you're a leader of an organization, what you're going to hear from us today is, well, how do you need to reboot yourself so that you don't crawl out of the rubble and go back to old work ways, but you, what I call, don't go back to work, you go forward to work,” Keith says. “How do you leap forward 10 years out of the pandemic?”

He addresses those questions in his new book, “Competing in the New World of Work: How Radical Adaptability Separates the Best from the Rest.” With equal parts vulnerability, authenticity and honesty, Keith walks you through how to become the best version of your career self. 

For example, he’ll talk about the importance of collaborating with your colleagues to focus on growth and learning, challenging your assumptions to build empathy and why without resilience you won’t make it far. You’ll also get a look into specific tools and apps that can help you build resilience from a distance, with trust.

Keith talks about a “Go Forward to Work” project he led during the pandemic that documented best practices and innovations happening in the workplace. Here’s what he found: “The pandemic gave people courage to shoot through the shit and state the truth, because there was an emergency going on and we rose to an occasion, and we didn't give a shit about silos.”

In a post-pandemic world, it’s absolutely necessary to master radical adaptability. If you’re looking for ways to catapult your career or organizations forward, and not get lost in the chaos of change, you don’t want to miss the knowledge and practical tips shared in this episode. 

Get Keith's Exclusive FREE Video Course


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Feb 10, 2022
How Big Pharma Corrupts Medical Knowledge – Dr. John Abramson : 901
01:20:48

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn about the harm of Big Pharma and the reasons why pharmaceutical drugs are becoming much more widely used than science or good health care justifies. 

Corporate interests and public good in America are often at battle, and the world of medical research and care is no different. Dr. John Abramson joins the show to explain what that means for your health and what you can do about it.

Dr. Abramson is an expert on health care policy, inside and out. 

He’s taught at Harvard Medical School for 20 years and spent more than 20 years as a family physician. He’s researched, written about, and had unique access to the inner workings of the pharmaceutical industry for decades. He’s served as an unpaid consultant to the FBI and Department of Justice, and as an expert in national drug litigation. 

He’s also written a new book, “Sickening: How Big Pharma Broke American Health Care and How We Can Repair It.” He joins the show to talk about how big pharma controls research, withholds data and shapes information that medical professionals rely on to make important care decisions. 

He shares the stories behind four of the biggest failures in the pharmaceutical world that include deception, illegal practices, exploitation and lies. He’ll discuss how the job of pharmaceutical companiesno matter how effective a project may beis to make a profit. It’s important to never forget that, Dr. Abramson says.

Dr. Abramson offers ways you can put your trust back in science and take your health into your own hands in a world of corporate giants. Opening scientific data for independent analysis is a good start. This episode offers information so you're aware and you can make better decisions for yourself.

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Feb 08, 2022
Sex Life Upgrade: Find a Style That Connects Your Body & Mind – Layla Martin & Mistress Natalie : 900
00:36:43

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… two experts with very different approaches to sex illustrate exactly how one size does not fit all. Sex is a uniquely personal choice.

 From the mystical to the unconventional, this podcast doesn’t shy away from candid conversations about sex. There’s a lot to learn. No matter what your life stage or circumstance, understanding how sex benefits your body and mind can dramatically improve your life. 

Layla Martin studied human sexuality and human biology at Stanford and then spent a decade learning from Tantric masters in the jungles of Asia. She combines modern science with the effective practices of Tantra to inspire people to heal trauma or shame and fully awaken their sexuality. As the founder of the Tantric Institute of Integrated Sexuality, Layla teaches people how to experience more epic sex and legendary love through her trademarked VITA™ Method.

Mistress Natalie lives at the intersection of BDSM and biohacking, a unique (and pretty cool!) place to be. She’s spent more than two decades doing BDSM with her clients, specializing in kinky coaching, luxury domination and BDSM therapy. Along the way, she’s continued to evolve and research her field. She also earned certifications in life coaching, personal training and yoga. More recently, she’s explored the idea that practicing your kinks can lead to some serious performance upgrades. 

There’s more! If you liked this special episode with Layla and Mistress Natalie, listen to their full podcasts about sex. And check the “Links & Resources” section below for other info to upgrade the many aspects of your sexual wellness.

Altered States of Sex – Layla Martin – #651


50 Shades of Dave with Mistress Natalie – #341

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Feb 04, 2022
How to Control, Reframe and Change the Chatter in Your Head – Ethan Kross, Ph.D. : 899
01:10:53

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IN THIS EPISODE OF THE HUMAN UPGRADE...

 … you’ll find out how to harness the power of your inner voice to ease anxiety, improve physical and mental health, and deepen your relationship with others. 

“The mind is flexible, if we know how to bend it,” says psychologist and award-winning professor Ethan Kross, Ph.D., founder of the Emotion & Self Control Laboratory at the University of Michigan.

He’s one of the world’s leading experts in controlling the conscious mind. He studies the ways in which your inner voice impacts your health, performance, decisions and relationships. He explores how people manage their emotions in order to better understand self-control. In particular, the conversations you have with yourself directly impact every part of your health and life.

He explain that your inner voice functions to do things like this:

  • Keep information active in your mind
  • Coach you through problems
  • Simulate and plan ahead
  • Tell you stories

That inner voice can be a powerful tool, giving you creativity, connection and definition. However, when the voice turns to negative and disorienting self-talk (chatter), it can create chaos and overwhelm by zooming into our problems, making you lose perspective.

Ethan’s pioneering research mixes behavioral and brain research to get at the “why” behind human nature. He uses insights from his research to give people science-based tools they can use to change their behavior, be used in relationships, support a career move, improve physical performance, decrease stress, increase productivity and be used to reach life goals. You’ll use new tools like mental time travel, tough love and introspection.

In this conversation about his new book, “CHATTER: The Voice in Our Head, Why It Matters, and How to Harness It,” you’ll learn: 

  • How social media plays a part in our chatter
  • How to zoom out with a flexible mind, changing thoughts and distancing ourselves
  • How to use tough love
  • How to teach your kids about chatter from a young age
  • How to help your friends with their own chatter (and what makes it worse)

With Ethan’s experience studying the conscious mind for 20 years, you can learn how to turn negativity into an awesome tool that helps you master your own self-talk.

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Feb 02, 2022
When WTF Means Your Freedom’s At Stake – Dave Asprey : 898
00:22:36

IN THIS *BONUS* EPISODE OF THE HUMAN UPGRADE™...

Dave goes live – and solo – on Telegram to talk about the state of the world according to one of his four Fs: Freedom. (The others are fear, food and fertility). From your biology to your right to protest, freedom means you get to decide what’s right for you.

“The need to be free is so you can perform your role in the greater organism, Dave says. "And this is why whenever we have central authority and central control, we end up with overreach. And when there is overreach, there is, universally, throughout all of human history, you push and you push and you push as a government until people lose it, and then they inevitably change things.”

Websitehttps://daveasprey.com

Telegramhttps://t.me/aspreyofficial

YouTube: https://www.youtube.com/c/daveaspreybpr

Membership: https://www.ourupgradecollective.com

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Jan 31, 2022
Mini-Episode: Cool Facts Friday #19
00:16:43

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • 3 things indicate whether you’ll look for information or remain ignorant 
  • Deadly anthrax toxin could be a new pain reliever
  • Multiple break-ups and solitary living linked to inflammation in men
  • Insects may be the next big thing in animal protein alternatives
  • Nerve cells in the brain suppress reproductive hormones when cortisol is too high
  • Stress before and during pregnancy alters infants' cellular aging

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Jan 28, 2022
Stay Sick or Eat Meat? Facing a Vegan Crisis – Monica Hershaft : 897
01:23:02

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IN THIS EPISODE OF THE HUMAN UPGRADE...

Monica Hershaft brings an interesting perspective to the choices of living your life vegan, vegetarian or animal-centric.

She grew up in a vegetarian, then fully vegan family. Her father, Holocaust survivor Dr. Alex Hershaft, co-founded the modern animal rights movement in the U.S. more than 40 years ago. 

She speaks to the ethical, moral and deeply traumatic reasons people choose veganism. Those points cannot be dismissed. Nor can the implications of a completely plant-based diet without animal protein on human health.

Monica shares her story of being an active, athletic teen and continuing veganism into adulthood. It was a trendy detox program at age 34 that triggered her rocky, decade-long health journey from debilitating sickness to finding health solutions. 

“It didn't even occur to me as a child to think anything different because that's just how I was raised and that's how we ate,” she explains. “Eventually, when I did grow up and get sick, it took a while for me to even consider that it could be my diet. So, it was a very big pivot mentally to make that leap.”

She also wrestled with coming out as Paleo to her father and what discarding veganism meant for her family relationships. “I had to be willing to lose the relationship, to stand up for what my truth was,” she says. Healing her physical and mental health led the hard discussions: “I'm going to be eating animal protein at every single meal, because I believe that that's how I can keep my life and my health,” she recalls saying. 

Monica’s now a bestselling author, motivational speaker, holistic health practitioner and nutritional consultant. She founded a top-rated holistic wellness center in Los Angeles and recently relocated to Scottsdale, AZ where she works 1:1 with patients to get their health back. She helps people heal from illness that other medical professionals often label a “mystery.” 

You’ll gain valuable information from this conversation, such as:

  • how to assess your symptoms, 
  • how to understand nervous system switching and blocking,
  • the important relationship between the vagus nerve and an allergic state,
  • food checklists to follow, 
  • how to recognize harmful food propaganda,
  • why fungus and metals are the big thing (in vegetarians/vegans),
  • why animal welfare and good soil matters,
  • educational videos to watch, 
  • programs to attend, and,
  • how to find help from functional, alternative and holistic professionals.

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Jan 28, 2022
Hype or Hope? Semaglutide Changes the Weight Game – Dr. Robert Kushner : 896
01:01:43

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IN THIS EPISODE OF THE HUMAN UPGRADE...

…you’ll learn about semaglutide, a new weight loss drug that’s been getting a lot of attention. 

Highly respected obesity expert Dr. Robert F. Kushner joins the show to talk about new research findings. He was part of a team that published semaglutide study results in the New England Journal of Medicine this past year. Looking into semaglutide, typically used for Type 2 Diabetes, showed that it also reduced body weight.

We talk about how you might use semaglutide, both from an aging perspective and from a weight loss perspective. You look at risk reward for everything you can do, and then you decide what's going to work best for you. There's some interesting knowledge to be gained from the research on semaglutide.

Here’s the short version of how it works: “Semaglutide mimics our naturally occurring hormone called GLP-1,” explains Dr. Kushner. “When you give it back to a person in pharmacologic doses or high doses, but it mimics what we normally have, it augments or highlights this feeling of, "You know what, I am really not as hungry as I was before. I'm more full than I was before, so I don't need as much food." It's actually the change in appetite that causes a weight loss that we see with this kind of a drug.”

A clinician, educator and researcher, Dr. Kushner has spent his decades-long career on adult weight management for adults. Board certified in both internal medicine and nutrition, he maintains a medical practice, teaches students and medical professionals, and presents around the world. He’s written more than 250 original articles, as well as reviews, books and medical book chapters.

He’s Medical Director of the Center for Lifestyle Medicine at Northwestern Medicine in Chicago; a professor of Medicine in the Division of Endocrinology and a professor of Medical Education at Northwestern University Feinberg School of Medicine.

This episode’s conversation includes the role of lifestyle in weight management. It’s shortsighted to view semaglutide as a wonder drug isolated from diet, exercise and even mental health. It’s all related. And new understanding of obesity as a disease and its biological drivers helps the search for lasting solutions, including training for healthcare professionals.

Listen on to find out more about semaglutide and six factors that might be causing your weight gain or making it difficult for you to lose weight.

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Jan 26, 2022
Hacking Eyesight – Interventions with Dave – Mark Bell : 895
00:48:05

IN THIS EPISODE OF THE HUMAN UPGRADE...

 … Dave talks with Mark Bell about eyesight and ways to approach vision problems. 

Mark is a world record-breaking powerlifter, the owner of Super Training Gym, The Strongest Gym in the West, and the inventor of the Sling Shot, a bench press accessory tool to help lifters add pounds to their bench press, help lift through injuries, and reinforce proper technique.

He’s built a life and business based on high performance. So when he began experiencing worsening vision over the past several years, he wanted to know how he could improve it.

“There's strength and there's flexibility,” Dave says. “And as you age, your eyes, the muscles lose strength. The tissues lose flexibility and this has to do with collagen types and cross linking of collagen. You're actually seeing yellowing of parts of the lens in your eye. And then, there's also a neurological thing where the brain may not actually be connecting.”

In this “Interventions with Dave” episode, you’ll learn about:

  • Effective supplements for eye health 
  • How mitochondrial health affects vision
  • The importance of morning sunlight
  • Eye exercises to restore ability to focus based on the Bates Method and Meier Schneider’s "Yoga For Your Eyes"
  • Gabor patches to stress your brain's visual perception area
  • Eye training using an app, like GlassesOff.
  • Palming 
  • IV stem cells


More about Mark Bell


Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.

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Jan 21, 2022
Free to Choose: Your Guide to Personalized Longevity Medicine – Liv Health : 894
00:46:57

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn about a new model of healthcare focused on personalized longevity medicine. This custom telemedicine solution uses your own data to reach goals you have for the quality and length of your life.

Andrew Wax, an Integrative Health Specialist and Director of Clinical Care at Liv Health, joins the show to walk you through the Liv Health model that’s putting people in control of their own medical care.

Do any of these statements apply to you?

  • You consider yourself a biohacker
  • You’re looking for a greater degree of medical freedom
  • You want more customized care than you’re getting from your primary care doctor
  • You’ve been on a medical protocol and have stopped making progress or seeing results

 

If you’re age 18 to 85 (and older) and want to target sleep, cognition, body composition, nutrition, fitness, hormones, immunity, or gut health –  Liv Health’s precision medicine approach may be right for you.

Andrew’s extensive experience includes working with patients and physicians to develop anti-aging and regenerative protocols. He’s earned multiple degrees in the areas of physiology, biochemistry, psychology, and a certificate of neuroscience. He’s certified in peptide therapies and is the former director of the Medically Managed Peptide Program at the Boulder Longevity Institute.

He and the entire Liv Health team bring related education and experience to Liv Health, where care includes hormones, peptides, novel small molecule drugs, supplements, fitness, nutrition, and other lifestyle interventions. 

In short, Liv Health is goal-based medicine. You come in with a goal, and your Liv Personal Performance Team (PPT) creates the path to get you there. You get a step-by-step guide to custom-curated protocols and treatments based on your individual data. Your PPT includes a patient support coordinator, health concierge and doctor. 

It’s important to note that Liv Health services don’t replace general medical care from your primary care doctor. Consider Liv a supplemental service that helps you target particular longevity goals.

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Jan 21, 2022
Ways to Build a Resilient Family – Joe De Sena : 893
00:58:48

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… One “Tough Mudder” Joe De Sena shares tips on how you can build mental toughness and resilience within your entire family.

Over more than a decade of work, Joe De Sena built Spartan into the world’s leading endurance sports and wellness brand. He also created one of the most popular obstacle-race series in the world, Spartan Race. He’s convinced a community of more than 10 million people to voluntarily embrace the experience of  “tough fitness.”

“I want you to give me the worst stuff you got,” Joe says. “The turmoil, the pain, the suffering, and [then] give me the strength I need to deal with it. Just keep it coming. And so that became the Spartan prayer, like give me the shitty days, give me the failure, because I know I'm going to become better at dealing with that.”

It’s not until you reach the edge and get through it that you realize how much you’re capable of. But does tough mean resilient? And does that level of influence translate to family dynamics? That’s the conversation we dig into specifically for parents and kids. 

Joe’s always had a passion for endurance and activities that push his mental and physical limits. During the pandemic, he looked closer to home and found ways he could be a better parent. He believes how you react to challenging situations defines you and your family.

His latest book, “10 Rules for Resilience: Mental Toughness for Families,” talks about defining and creating resilience. “This book was born in 2020, while I watched as families all over the globe faced the discomforts thrust at them and realized how insanely unprepared most people are for difficulty.”

During this time in our history, the pressure, stress and unpredictability in bigger amounts than ever made clear that it was essential to develop more resilience. 

Joe’s term, “True Resilience” describes a body and mind carved out of hard work, challenge, and failure. He says it takes True Resilience to approach overwhelming situations with calm and confidence, to not get rattled, anxious, or angry, and even to embrace failure, setbacks, and redirections.

It also means listening and responding with intention: “Much of your success will depend on your ability to discern what sparks enthusiasm and motivation in your child,” Joe says. “Find your kid’s flow.”

Here’s some of what you’ll find in “10 Rules for Resilience: Mental Toughness for Families:”

  • Proven techniques from clinical research and experience to set the whole family up for better, more effective coping skills.
  • Family activities that supplement each rule of resilience and help you put the reading material into real-life action.
  • A values exercise to help your family create a solid vision statement.
  • A five-step model to increase your fear IQ.


Listen on as Joe shares the benefits of training your kids in hard work, traveling as a family, and pushing yourself to the limit as a parent. 

Note: Joe co-wrote “10 Rules” with Dr. Lara Pence, a clinical psychologist and Chief Mind Doc at Spartan.

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Jan 19, 2022
Why Lying to Yourself Could be a Good Thing – Marisa Peer : 892
01:01:38

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IN THIS EPISODE OF THE HUMAN UPGRADE...

…you’ll learn about a therapy method that gets to the root of your problem and solves it within one to three sessions.

 “The main reason it works, I believe, is that it overcomes the high level of resistance that most people have to changing fundamental beliefs about themselves by getting to the deepest core of their belief very quickly,” says Marisa Peer. 

Marisa is a clinical psychologist and expert in human behavior who developed a new way to approach your mental health — Rapid Transformational Therapy® (RTT®). RTT offers the same benefits of traditional therapy, but on a much quicker timeline.

“I didn't understand why therapy, which is also dealing with pain, had to be so long. I never got that ‘turn up with your pain every week,’” she says. “We'll keep reopening the wound. And one day, you might get better.”

She’s also an international best-selling author of multiple books, motivational speaker, personal development expert and leading celebrity therapist. She’s worked with people around the world and most of them have a story they tell themselves about not being “enough.” Her newest book puts the focus squarely on the personal narrative you’re clinging to:  “Tell Yourself A Better Lie: Use The Power Of Rapid Transformational Therapy To Edit Your Story And Rewrite Your Life.” 

​​“After 30 years of private practice, I created Rapid Transformational Therapy (RTT) because it was clear to me that so much of the pain and suffering we see in the world comes down to the fundamental stories we tell ourselves and how often those stories are untrue or outright lies,” she explains. RTT has roots in hypnosis.

Marisa helps people pinpoint the reasons behind why people want what they want, so they can actualize a meaningful life for themselves. She uses a solution-oriented technique that can make you mentally stronger, more confident and even more loving towards yourself. 

He who hesitates is lost,” she says. “While you're waiting to write your book or start your company, someone else is going to come along and write that book and start that company. So, time is the one thing we don't have access of. And so, I think they'll always be people who like that long method [of traditional talk therapy] and a lot of people who don't like it. And I think we can definitely accommodate both.”

It’s time to start telling yourself the truth about who you are. “Our greatest pain is caused by the lies we tell ourselves,” Marisa says. She offers candid advice on how to help you recognize the harmful story you tell yourself and how to change it to a better one.

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Jan 14, 2022
Get Moving! Align Your Body, Align Your Life – Aaron Alexander : 891
01:04:40

IN THIS EPISODE OF THE HUMAN UPGRADE...

 … Body movement expert Aaron Alexander joins the show to talk about how to integrate healthy movement practices into your daily life.

You’ve likely heard that sitting is the new smoking – well, good news: It’s not the sitting itself, but how you sit, that affects your well-being. In fact, all the ways you hold your body and move your body matters. Body language and how you move through space tells others how comfortable you are, how truthful and trustworthy you are, and more.

Most of you have built up body movement around a collapse state, which can lead to physical and emotional pain. Aaron spent years traveling the world, discovering how other cultures defined and measured health and studying movement behaviors. He found that the healthiest cultures incorporate aligned movement and sitting styles into their day-to-day activity. 

Take walking for example. “When you're out taking a walk, it's like you are literally playing symphony of your physiology,” he says. “Walking is one of the healthiest things that a person can do–just going out and getting yourself into that contralateral motion, contralateral being just like walking pattern. As you're doing that, you're stimulating your brain function, you're also stimulating things like peristalsis and digestion and organ function.”

Aaron is a manual therapist, using movement techniques inspired by yoga, martial arts, chiropractic skills and more. He also hosts the popular Align Podcast, and wrote  “The Align Method: A Modern Movement Guide for a Stronger Body, Sharper Mind, and Stress-Proof Life,” which shares the tools you need to reshape your environment for enhanced creativity and longevity.

Healthy movement incorporating play and adaptability enhances creativity, resilience and creates a healthy nervous system. During the show, Aaron goes over the five daily movements to integrate into your life and how to get started in a productive, gentle and playful way.

“Your body is so darn adaptable that if it's just a matter of you need to give it a baseline of the raw components to be healthy,” says Aaron. “If for a moment you're slouching over a chair, I love that. There's no problem with that, it's the repetition of that. If for a movement you're looking into a wall or into a blue light or whatever, you're not going to just explode.”

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Jan 11, 2022
Recalibrate Yourself with Quantum Energy – Philipp Samor von Holtzendorff-Fehling : 890
01:05:10

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’re going to learn about quantum energy and the science behind how and why it works.

Philipp Samor von Holtzendorff-Fehling founded Leela Quantum Tech to further develop and share the power of quantum energy. Quantum energy fields are different from harmful EMFs you’re told to avoid. Here are a few of the benefits of quantum energy, also known as “frequency medicine.”

  • Improves your blood and cellular health
  • Increases your fitness level and speeds up recovery 
  • Intensifies the taste of your food and extends its shelf life
  • Eases pain and activates your own inner healer
  • Improve the quality of your water at home and on the road.
  • Helps you become more resistant to stress and more efficient in your daily tasks
  • Prevents exhaustion so you’re able to focus better
  • Allows you to worry less and enjoy the moment


But how can quantum energy and specific frequencies have such a powerful effect on humans, animals and even plants? Philipp looked to science for the answers. Leela submits its products to be scientifically studied by third party institutes and doctor’s offices. 

Leela concentrates pure quantum energy in specific plates and aligns them to create a highly concentrated field and quantum energy space. Examples are the Leela Quantum Bloc and Infinity Bloc. They’ve also developed frequency cards, capsules and clothing.

“There's so many people that may want to enjoy support like that, and they don't understand it,” Philipp says. “And for them, you need to provide something for the brain to read through it, and that's what we've done.” 

So far, the research studies found quantum energy frequencies:

  • Block, neutralize and bring EMFs into harmony 
  • Positively impact the autonomic nervous system and heart rate variability
  • Positively impact organ function, cellular health and blood health
  • Neutralize harmful frequencies like herbicides, pesticides and cesium 137
  • Boost body and energy function in 100% of cases

 

Some of that testing includes measuring EMFs or using dark-field microscopy to measure voltage in the cells. Leela’s other research projects are studying the benefits of quantum energy frequencies for autistic kids, athletes, and people experiencing chronic Lyme disease.

This fascinating topic gets into other frequencies, too, like molecular, etheric, and sound. Listen on to find out how you can use the power of energy frequencies to upgrade yourself.

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Jan 06, 2022
How Neuroinflammation Disrupts Your Immune System – Gary Kaplan, D.O. : 889
01:07:27

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… you’ll learn about neuroinflammation and its connection to the immune system from integrative medicine pioneer Gary Kaplan, D.O. The conversation gets into many topics like the immune system, infections, chronic disease and why your brain may be on fire. It’s all connected!

Dr. Kaplan is a pro at alleviating chronic pain and illness in the field of integrative medicine, by combining integrative and alternative strategies. Conventional thinking about chronic pain and depression is flawed, he says, as more research shows often those symptoms are rooted in inflammation in the brain. 

Three major causes of inflammation include environmental factors, childhood trauma, and epigenetics and genetics.

Inflamed brains, specifically, cause mental, emotional and physical pain like depression, anxiety, chronic fatigue syndrome, chronic fibromyalgia, pediatric neuropsychiatric disorders and more, he says.

Dr. Kaplan’s treats patients at the Kaplan Center for Integrative Medicine he founded in 1985. He’s board-certified in Family Medicine, Pain Medicine, and Medical Acupuncture. He’s also studied and practiced Osteopathic Manipulative Medicine, Emergency Medicine, Herbal Medicine and is certified in Chelation Therapy.

Virtual Conference Zeros in on Neuroinflammation 

Dr. Kaplan’s drawn on his interest in brain inflammation, the immune system and chronic disease to assemble experts from around the world. This group will share new developments and research about chronic illness at a virtual conference in February 2022.

The conference topics will cover brain inflammation due to immune dysregulation. You’ll also hear about new breakthrough data on diagnosis and treatment of long-hauler Covid. It’s open to the public and healthcare professionals.

  • “Symposium on Autoimmune Encephalopathy Secondary to Infectious Disease: A New Perspective on the Pathogenetic Interaction of the Immune system, Infection and Chronic Disease”
  • Feb. 9, 10, 11, 2022
  • Early bird pricing = $69 before Jan. 10. Regular pricing = $99 after Jan. 10
  • Webpage: www.hopehealingknowledge.com
  • Landing Page (with agenda & speakers)
  • Registration

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Jan 04, 2022
Upgrade Your Metabolic System with the Right Foods – Dr. Robert Lustig – Best of 2021
01:12:14

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IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…

 … Dr. Robert Lustig’s knowledge about the metabolic system landed with listeners in a big way.

He’s a New York Times bestselling author of several books about the problems caused by sugar, processed food and the health conditions of obesity. 

In his latest book “Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine,” he focuses on how real food can reverse chronic disease and promote longevity. He also challenges the current healthcare paradigm and the influence of Big Food, Big Pharma, and Big Government. 

“I wrote Metabolical to basically explain what is healthy,” Dr. Lustig says. “And based on the empiric data, based on the science, based on the pathologies that I describe in the book that belie chronic disease, I distilled all of the information down to six words – two precepts, six words: ‘Protect the liver, feed the gut.’”

These are the eight cell pathologies that underlie all chronic disease, according to Dr. Lustig:

  • glycation
  • oxidative stress
  • mitochondrial dysfunction
  • insulin resistance
  • membrane instability
  • inflammation
  • epigenetics
  • autophagy


"[When] you look at the entire molecular mechanism of every single one of those eight subcellular pathologies, none of them have a medicine," he says. "None of them are druggable. They're all foodable." 

His book also documents how processed food has impacted human health, the economy, and the environment over the past 50 years. 

“It’s not about obesity, it never was,” Dr. Lustig says. “The key to the kingdom is that it is not about obesity, it is about metabolic dysfunction and anyone can get it, and that’s what makes it a public health crisis, because obesity is a result of the problem, not the cause.”

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Dec 30, 2021
Upgrade Your Energy with a Hormone-Gut-Immune Trifecta – Dr. Amy Shah – Best of 2021
00:59:59

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IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…

… Dr. Amy Shah’s approach to managing energy struck a chord with listeners.

Dr. Shah, a double board-certified physician, searched for a complete mental, hormonal, and inflammatory reset after she experienced a car accident and personal energy crisis.

And while she uses an integrative and holistic approach to wellness in her medical practice, what she learned about energy and fatigue connected a lot of dots.

Regulating the “energy trifecta­,” made up of balanced hormones, a well-functioning gut, and a healthy immune system, makes all the difference. (She’s also an expert in circadian rhythm fasting.) 

“These three areas communicate, and they talk to the brain constantly,” says Dr. Shah, who studied and trained at Cornell, Columbia, and Harvard Universities.  “And if any of those are broken, then you're going to be tired. And so things like short fasting, circadian fasting, sinking with nature and circadian rhythms, which is our internal clock and eating the right foods really can make a difference. And of course, there's this whole component of mind, body health, which we sorely miss in Western culture.”

 What you eat, when you eat and mind-body health rule your energy patterns and likely could be the root cause of your fatigue. She lays out solutions in her book, "I'M SO EFFING TIRED: A Proven Plan to Beat Burnout, Boost Your Energy, and Reclaim Your Life."

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Dec 28, 2021
Kindness: The Win-Win Superpower – Jamil Zaki, Ph.D. & Leon Logothetis : 888
00:34:20

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IN THIS EPISODE OF THE HUMAN UPGRADE...

… the conversation centers on what kindness is, how to practice it, and why it matters. Kindness is a powerful tool – it helps people feel less alone and truly makes the world a more joyful and tolerant place. The two insightful guests you’ll hear from in this episode – Jamil Zaki, Ph.D., and Leon Logothetis – will leave you feeling lighter, more optimistic and, well, kinder!

Jamil Zaki, Ph.D., uses tools from psychology and neuroscience to help you understand how empathy works. As a professor of Psychology at Stanford University and the director of the Stanford Social Neuroscience Lab, he explains how kindness is a learnable skill. You can use it in your life more often.

Jamil’s kindness research includes empathy and compassion to form a triad. “Kindness is a behavior that benefits another person,” he explains. Scientists view empathy like a big umbrella term for emotional connection and then compassion as one of the components of emotional connectedness to others.

You can dive into more of his research in his book, “The War for Kindness: Building Empathy in a Fractured World.”

Leon Logothetis invites you to join the kindness rebellion. He’s certain you’ll find wealth in health and happiness, success in inner peace and a definite cool factor in being kind. 

Leon’s a motivational speaker, adventurer and philanthropist known as the “The Kindness Guy.” His travels take him all over the world looking for and spreading kindness (binge watch both seasons of “The Kindness Diaries”). He speaks to children and adults at schools and companies about the importance of being kind in the world. Empathy and compassion have a lot to do with that.

Check out his latest book: “Go Be Kind-A Life-Changing Little Journal: 28½ Adventures Guaranteed to Make You Happier,” to find out how you can get in on the kindness movement.

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Dec 23, 2021
How to Build Your Emotional Agility and Resilience – Susan David, Ph.D. & Joan Rosenberg, Ph.D. : 887
00:38:23

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IN THIS EPISODE OF BULLLETPROOF RADIO...

…you’ll learn that being adaptive to change is a skill you can cultivate. One of the most sustainable ways to keep going with the flow is knowing how to build emotional awareness. These two guests give tips on managing your emotional states so you can be more resilient in all areas of your life.

Expert psychologist, trainer and speaker Joan Rosenberg, Ph.D.guides yoou to achieve your highest potential by teaching you how to be in control of your own emotions. 

Award-winning Harvard Medical School psychologist Susan David, Ph.D., describes all the psychological skills necessary for you to thrive in uncertain times. She challenges the common attitude that you have to “fix” your difficult emotions through positive thinking. 

“Emotional agility is about the capacity to be with ourselves,” Susan says. “That includes our difficult thoughts and emotions and stories and past experiences in a way that's compassionate and curious and that doesn't hold us back from being the people that we most want to be.”

Since you can’t get away from emotions, there’s power in knowing how to deal with them. “We've got to be able to reconnect with ourselves so that we can move forward in the world,” Susan says.

Get ready to learn some foundational skills that will make you an emotional agility pro.

About Joan: The author of 90 Seconds to a Life You Love: How to Master Your Difficult Feelings to Cultivate Lasting Confidence, Resilience, and Authenticity,” teaches you how to be in control of your own emotions.

Joan guides you through eight unpleasant feelings she’s pinpointed: sadness, shame, helplessness, anger, vulnerability, embarrassment, disappointment and frustration. She says the best way to approach these feelings is with confrontation and empathy.

  • “The single most important thing I can do is to recognize someone’s pain, and just in essence, hold a mirror up to it, even if it sounds like you’re saying the things that are so obvious,” Joan says. “It has a huge impact of calming someone else’s nervous system down.”


About Susan: She’s the author of “Emotional Agility: Get Unstuck, Embrace Change, and Thrive in Work and Life,” based on 20 years of research of how to get through uncertainty 

  • “For people to be healthy with themselves, with the inner worlds, these are not soft skills,” Susan says. “These are the most fundamental skills that we can have as human beings.”

  

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Dec 21, 2021
Mini-Episode: Cool Facts Friday #18
00:10:05

In this Episode of The Human Upgrade™...

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Beer & blue cheese found in ancient feces
  • Blood marker detects dementia early
  • Team flow shows up as a unique brain state
  • Trauma-focused psychotherapy works for PTSD
  • MDMA improves PTSD symptoms 


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Dec 17, 2021
Erectile Dysfunction: Causes, Solutions and Why It’s Normal – Dr. Paul Thompson : 886
01:25:52

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

 …urologist, surgeon and age medicine specialist Dr. Paul Thompson discusses the challenges men can experience with their sexual health, energy and performance. 

Erectile dysfunction happens to men at all ages and is actually quite normal. 

Causes can be physical, and hormones play a role. Nutrition or exercise habits may be culprits. And state of mind factors in.

Dr. Thompson shares his clinical expertise on how getting to the root of what’s going on with men's sexual functioning will not only improve erectile dysfunction but also support other critical areas of men’s health. 

The conversation looks at the pros and cons of eating meat, what your cholesterol numbers really mean, and why cardiovascular health matters at every age.

Guys, listening to this, if your doctor isn't asking you for Lp-PLA2, which is an enzyme that's expressed when there's damage to your arteries, then you have a problem. If they aren't looking at C-reactive protein, you have a problem; and if they're not looking at homocysteine, you have a problem. So, you could ask your doctor for them or you could ask your doctor, “Hey, what do you know about these?”

You’ll also find out why oral health is so important and why you have to pay attention to your nitric oxide production.

Dr. Thompson talks about the at-home device he helped develop at Launch Medical (he’s chief medical officer there) that's pioneering a solution for erectile dysfunction. It’s based on clinical acoustic wave therapy treatment. “Acoustic wave is really simple and it works, and it has to do with the growth of blood vessels,” he explains. The Phoenix device helps men improve and/or restore their sexual functioning.

Guys and women who love guys or guys who love guys, this thing is real technology. It does work, it is not too good to be true, and it's worth talking about.

This conversation takes any embarrassment or shame out of the ED equation and gets into the details of plaque, blood flow and how you can find a fix and reclaim your sexual health.

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Dec 16, 2021
The Stress-Sleep Connection That’s Keeping You Up at Night – Dr. Dave Rabin : 885
01:10:18

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

...you'll learn about the impact of chronic stress in humans, how it wrecks your sleep and what you can do about it.

For more than a decade, neuroscientist, board-certified psychiatrist, health tech entrepreneur and inventor David Rabin (an M.D. and Ph.D.) has been immersed in the science of stress. He’s been researching causes and ways to manage it. He’s also been helping people deal with the consequences of both acute and chronic stress.

He’s back on the show (don’t miss episodes #729 and #730) to talk about how stress disturbs systems of your body and mind, which, of course, affects your sleep.

Stress is not inherently bad because we require it to grow, Dr. Rabin says. “We require the stress to help us learn how to overcome the challenges that are signaled by the stress to become better, stronger, fuller versions of ourselves.” … “There are the situations where we start to see acute stress that can be healthy and very helpful to growth turn into chronic stress,” he continues. “And that chronic stress increases inflammation on a daily basis. It’s that chronic stress that increases likelihood of disease.”

Dr. Rabin co-founded Apollo Neuroscience, a company that developed the first scientifically validated wearable technology that actively improves energy, focus and relaxation. This tech uses a novel touch therapy that signals safety to the brain. In new studies, it’s had a terrific impact on stress and sleep.

“Health means the restoration and maintenance of balance for all of us,” Dr. Rabin says. “Critically important is managing our sleep and our circadian rhythms, and our sleep and wake cycles. Maintaining sleep and making sure we do things to have a healthy sleep rhythm is going to maximize our performance and energy availability during the day and psychedelic medicines and wearables can play as important to role in that for us as the day-to-day practices of breathwork and meditation, yoga, exercise and nutrition.”

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Dec 15, 2021
Hacking Longevity Starts with Detoxification – Chris Shade, Ph.D. : 884
01:17:45

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

 … Christopher Shade, Ph.D., joins the show to take you through a new six-spoke “longevity wheel.” You’ll find out what you can do to live longer by managing toxins and hormones that influences aging.

With expertise in environmental sciences, chemistry and biology, he founded the Colorado-based company Quicksilver Scientific. It’s a group of “chemists, biohackers and age rebels.”

He specializes in the biological, environmental, and analytical chemistry of mercury in all its forms. He presents and teaches in the U.S. and nationally about mercury, environmental toxicities, neuroinflammation, immune dysregulation, and the human detoxification system.

He's designed detoxification protocols, unique supplement delivery systems, and a patented mercury speciation test. As CEO, he continually drives development and innovation. Right now, the focus is longevity with a foundation in detoxification.

Everyone has a meaningful amount of metals, plastics, molds or other toxins in their body and is pretty much operating with low-grade toxicity. And even though everyone has the same basic detoxification system, people react to and process toxins very differently. 

There’s a general universe of toxins: You have exogenous toxins from outside the body (metals, chemicals, mycotoxins or food-borne toxins). Then you have endotoxins, which are made on board usually by gut bacteria and lipopolysaccharide.

That’s why cellular level detoxification matters so much. Bile flow, and knowing what blocks it and what opens it, plays a huge role in your body’s detoxification process.

If you learn to think like a computer or especially a network engineer, there's a whole bunch of interrelated systems. If one of them is broken, it'll have an effect on the other. But when you look at detox pathways, you look at aging, it's a very similar mindset, way more so than you would think.

Hormones, too, get in on the aging action. DHEA and pregnenolone are the mother hormones. All the other hormones are made out of those two things. “Hormones are necessary for all the detox reactions,” Chris says. “Having the right levels of all the hormones just powers everything up.”

The six-spoke “Longevity Wheel” framework that Chris developed biohacks conventional aging assumptions. This wheel is a collection of biochemical pathways, mechanisms, and molecules that impact aging. Each spoke builds on another and all work together. 

  • Nrf2 and AMPK
  • NAD
  • Sirtuins
  • Telomeres
  • Senolytics
  • Neuroendocrine


Listen on to find out more about how detox, hormones and the spokes of this new Longevity Wheel can impact how you age.

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Dec 09, 2021
Toss the Candles! Biological Age Is Your New Birthday – Ryan Smith : 883
01:16:33

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

 …you’re going to discover how old you really are by taking a dive into the science of epigenetic methylation and biological aging. You’re going to find out about gene function, gene expression and what it has to do with how you age—and why it matters.

Biochemist Ryan Smith co-founded TruDiagnostic, a company focused on methylation array-based diagnostics for life extension and preventive healthcare. TruDiagnostic, a CLIA certified lab and health data company, developed the TRUAGE anti-aging test. 

From a small blood test, TruDiagnostic can tell you your biological age—how old your body acts, based on how it’s functioning (as opposed to your chronological age, which is the number of years you’ve been on Earth). 

Biological age is one of the most impactful pieces of data you can have about yourself. Age is the number one predictor of death, and your biological age matters more than the number of times you’ve been around the sun.  

For example, you could be 42, and if you take great care of yourself, your biological age may be 30… Or, if you take poor care of yourself, your biological age may be 60. 

Either way, TruDiagnostic will tell you how old you really are. And their test goes further than that. After you discover your biological age, TruDiagnostic also gives you a list of strategies to reverse aging based on your unique genetics. In other words, you get personalized anti-aging biohacks—and you can test your age over time to see if you’re getting younger, so you know whether or not your anti-aging hacks are working.

If you can turn back the clock on your biological age, you unlock the door to a longer, better life. 

It feels like the cusp of a big change in longevity research with science and data now more fully supporting this work. TruDiagnostic currently has over 30 approved clinical research studies underway investigating how epigenetic methylation changes impact how long you live and how well you age.

In this episode, you’ll also learn:

  • Why men age worse than women, and what you can do about it
  • The best ways to predict your biological age (hint: grip strength is one of them)
  • How getting COVID changes the speed at which you age
  • Why small amounts of stress are amazing for anti-aging (and the right ways to stress your body and brain so you age in reverse)

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Dec 07, 2021
A Bacteria That Guards Your Gut Lining – Colleen Cutcliffe, Ph.D. : 881
00:53:43

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 IN THIS EPISODE OF THE HUMAN UPGRADE™…

 …we get into the gut. If you’ve listened to my podcast before you probably know how much the gut is a culprit in disease. I’ve invited experts on the show to explain how without the right balance of good bacteria in your gut, you can have inflammation, poor immune response, GI distress and much more. 

Your gut lining is like a fence, explains Colleen Cutcliffe, Ph.D. It needs maintenance and attention, because that “fence” is what guards your gut from bad bacteria and toxins. Without it, you lose a strong defense system.

That’s where Akkermansia comes in. This bacterial strain naturally found in the gastrointestinal tract helps regulate the mucus lining of the gut, while also fine-tuning immune responses. 

Only in recent years have people understood (and acted on) the gut microbiome’s role in wellness or disease. Dr. Cutcliffe shares the research behind Akkermansia and why this probiotic is changing the gut health game.

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Nov 30, 2021
Mini-Episode: Cool Facts Friday #17
00:11:36

In this Episode of The Human Upgrade™...

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Migraines diminish the quality of your deep and REM sleep.
  • Microbiome bacteria can either help or harm people with Type 2 Diabetes.
  • A safer contraception option for men means no testicle injections.
  • Kids learn to manage big emotions by playing specially designed video games..
  • New studies show 6.5 hours of sleep could be surprisingly good for you.


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Nov 26, 2021
Alzheimer’s Targets Women’s Brains Decades Before Symptoms Show – Maria Shriver & Dr. Lisa Mosconi : 880
00:35:17

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

…  you’ll find out how Alzheimer’s impacts women more often than men and how symptoms begin decades before you think they do. Six million people in America are experiencing Alzheimer’s. Two-thirds of them are women. My guests, Maria Shriver and Dr. Lisa Mosconi, are championing an increase in research, raising awareness and providing resources about this topic to find out why. 

The Alzheimer’s spotlight falls twice yearly because it’s just that important: November for National Alzheimer’s Disease Awareness Month and National Family Caregivers Month, and June for Alzheimer’s and Brain Awareness Month. 

A lot of the research happening to understand Alzheimer’s can benefit everyone. It can teach you how to lessen inflammation in your brain and get a handle on or prevent immune and metabolic brain disease. When you learn how to do that, you unlock cognitive performance and longevity. 

Maria and Dr. Mosconi offer some great insight and practical tips.

Maria Shriver is a champion of Alzheimer’s awareness. For two decades she’s been reporting, writing and fundraising for it, specifically relating to how it impacts women. She founded the The Women’s Alzheimer’s Movement, a nonprofit that brings together doctors, researchers and brain experts to support Alzheimer’s research, clinical trials, and information sharing. It also provides public education, prevention tips and tools for brain health.

“I think what happens is that there are small moments along the way that we all disregard,” Maria says. I think the challenge to be present in our own lives is a challenge, really, for all of us. The challenge to take note of our health is a challenge for all of us.”

Dr. Mosconi is a neuroscientist and neuro-nutritionist focused on brain science, the microbiome and nutritional genomics, specifically the early detection of Alzheimer’s. Her research on women’s neurological health has changed the way science approaches the female brain. She speaks to the more than 10 years of research that shows Alzheimer’s starts with negative changes in the brain years – if not decades – before any clinical symptoms emerge.

“It’s really important to take care of ourselves, and our brains are really one of our most important assets,” Dr. Mosconi says. “And the best way to engage in prevention is now. It's never too late to start, but the sooner we start doing it, the better.”

Learn even more about how Alzheimer’s affects women and what to do about it:

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Nov 23, 2021
Temperature Hacking for Better Deep and REM Sleep – Matteo Franceschetti : 879
01:05:30

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

you’re going to learn a bunch of brand new sleep hacks, taken from over a million nights of sleep data. 

Those hacks will come from my guest Matteo Franceschetti. 

Matteo defines high performance—having been a professional skier, high-level tennis player, competitive race car driver and practicing lawyer. He didn’t get much sleep doing all those things, so he co-founded Eight Sleep and set out to create and advanced sleep improvement device so he, and everyone else, could sleep better and perform better.

We can all agree: “Sleep is a pillar, a fundamental pillar for your health,” Matteo says.

Eight Sleep tracks biomarkers that measure your sleep quality. Then it uses machine learning to make automatic adjustments to your sleep environment. This helps you optimize your sleep, get the reset and recovery your body needs, and well, wake up feeling better than you have in years. 

Best of all, you don’t actually have to do anything. You just go to sleep, exactly like you did last night, and the technology does all the sleep hacking for you. 

TIME Magazine named Eight Sleep one of its “Best Inventions” of both 2018 and 2019, and Fast Company listed it as one of the most innovative companies of 2018. They’re a sleep hacking company making big inroads into understanding and regulating your body’s temperatures while sleeping. This affects your REM sleep the most.

“While you are in REM your brain deactivates all the temperature controls in the body,” Matteo explains. “It doesn't let you fall into REM if it's too hot or too cold because you could potentially die. Changing the temperature based on your sleep stages and the different stages of the night is fundamental to maximize your deep and REM stages.”

And Eight Sleep has a fix for that.

“Based on your sleep stages and based on your biometrics, we adjust your body temperature during the night,” Matteo says. “It's not that we are inventing the wheel. Your body is already changing temperature during the night. It's part of your physiological process. We just enhanced that process to maximize your sleep performance.”

And then I wanted to know, “How many hours of sleep per night do you think you can save people, by just changing temperature?” The point isn't necessarily to get less sleep, but it's to live more. Right? If you just got everything you needed and it was as good as what you have today, but you had enough time to do two hours of reading or learning every day or meditating or parenting or whatever else, it's not about working more necessarily. It's just about living more. 

It’s exciting to talk to Matteo because he brings a whole bunch of new biohacking ideas to the table, er bed. He and I get into a bunch of sleep topics during this conversation, including:

  • How you can instantly increase your deep sleep by 40%, starting tonight


  • How you can reset your energy levels in the morning just by regulating your sleep temperature at night


  • How you can compress sleep down to 5-6 hours a night, while actually getting more rest and recovery


  • Why sleep consistency matters (and is still the hardest thing for people to do, well, consistently}


  • Why machine learning is the future of personalized health


If your sleep could use an upgrade, check out this episode for hacks you can implement right away and learn about what’s next in sleep technology. 

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Nov 19, 2021
How to Deal with Toxic People (Including Yourself) – Robert Greene : 878
01:24:26

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

… my guest fits right into the podcast transition to The Human Upgrade because he gets into the grittiness of what humans can do to level themselves up. No. 1 New York Times bestselling author Robert Greene shares science-backed knowledge about human nature.

You know you want to be more powerful, more in control and excellent at what you do.

Robert’s insights help you do just that. He gives you actionable tips that help you unlock limitations you may be putting on yourself so you can move your life upward and forward. (Similar to something I like to tell my team is great momentum: “up and to the right.”) 

World leaders, military generals, business executives, philosophers, and hip-hop moguls alike revere Robert’s books.

After writing about mastery and power for more than two decades, he’s now become a TikTok sensation and the universal truth for a new generation. 

He’s one of my favorite authors who’s profoundly influenced my own life and been on the podcast twice before. Both episodes are must listens: The 48 Laws of Power – #380 and The Laws of Human Nature – #575. I asked him back to talk about his latest book: “The Daily Laws: 366 Meditations on Power, Seduction, Mastery, Strategy, and Human Nature.” 

“In “The 48 Laws of Power,” I talk about deception and con artists,” Robert says. “But in The Laws of Human Nature, it's almost about self-deception, how we're con artists with ourselves, how we create an image of ourselves as being morally right, being a good person, being intelligent, being rational, being empathetic. Whereas in fact, we're usually quite far below that ideal. … Because your default position is to always look externally and blame other people.”

In “The Daily Laws,” he distills the best of his previous books and never-before-published material in to one amazing life guide for you. He lays out themes for each month of the year: Power, seduction, persuasion, strategy, human nature, toxic people, self-control, mastery, psychology, leadership, adversity and creativity. Within these themes he features a “daily law” for you to follow.

“By not looking at ourselves in an honest way, and glossing over our own flaws and weaknesses, we become trapped in patterns of behavior that we cannot control,” Robert says in his new book. “As the years go by, and the misreadings, missteps, and unrealistic decisions pile up, we can become bitter confused, and damaged.”

“The Daily Laws” is designed to reverse [these] toxic patterns and reconnect you to reality,” Robert says. “It takes aim at the various delusions we have all absorbed and seeks to attune your mind instead to the most entrenched traits of human nature and how our brains actually operate.”

Listen on for the truth bombs.

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Nov 17, 2021
How Postbiotics Upgrade Your Mitochondria – Dr. Anurag Singh : 877
01:03:10

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…I’m going down a rabbit hole of exciting scientific research and clinical studies supporting Urolithin A’s influence on your mitochondrial health. The short version? Urolithin A stimulates mitophagy and renews your mitochondria. Specific big things to know? It upgrades your cells, your strength levels and offers pretty powerful anti-aging benefits.

And a fun thing to know? The origin story of Urolithin A has to do with beavers. (!)

To find out the basis of Urolithin A and its relationship to pomegranates, check out my previous podcast featuring two experts on the subject: How to Get Fitter Cells, Stronger Muscles and a Longer Life – Timeline Nutrition with Dave Asprey – #772.

This time, I’ve invited Dr. Anurag Singh to the show. His expertise lies in clinical development and translational research. That means he translates new discoveries in science into real-world stuff you can actually use. He’s worked for several consumer health and biotech companies; authored more than 30 articles for top science journals; and designed and led more than 40 clinical trials over the last 15 years. 

As Chief Medical Officer of Amazentis, the parent company of Timeline Nutrition and the maker of Mitopure, a Urolithin A product. 

“A lot of times in the nutrition world, people put extracts and blends of probiotics together and they just give it to healthy people and expect magic to happen,” says Dr Singh. “Here, we've actually done the deep dive of the signs and how this molecule hits mitophagy and mitochondrial health. Then, bringing it to human translation and commercialization. This is really the holy grail for real world evidence.”

He’s spent seven years focused on Urolithin A research and clinical trials. His initial round of research with Urolithin A showed that it could increase aerobic endurance and increase grip strength. 

Urolithin A also is the first postbiotic shown to repair mitochondrial health via mitophagy. Mitophagy is the process of renewing your mitochondrial growth as you age. As healthy mitochondria get older they accumulate free radicals and reactive oxygen species. They lose shape and stop communicating with one another, too. These faulty mitochondria have need to be replaced. Urolithin A revs up the mitochondrial recycling.

Dr. Singh explains how you can get the benefits of Urolithin A and how to take it to achieve results.

“Our gut microbiome is very complex ecosystem with hundreds of millions of different species interacting with each other,” explains Dr. Singh. “They need to be interacting in perfect harmony to release these postbiotics, which is the way I look at it is the perfect gut health relationship within the microbiome. So it's not one bacteria. It's not one strain that you can isolate and give. It's really got to be multi-species. I think you can probably conceptually find that strain or probiotic that could do it, but the process will be so inefficient that the best way is to short circuit it and provide the postbiotic, which is Urolithin A, directly in a pill or in a food product.” 

Another direction for Urolithin A is sports performance. Amazentis teamed up with renowned researcher Dr. Louise Burke in Australia to look into how Urolithin A affects mitochondrial health in athletes. Those results will be available in 2022.

The future of Urolithin research keeps going in exciting new directions, including brain health. 

“So, there's a lot of research going on around this molecule,” Dr. Singh says. “[The] Buck Institute of Aging in California just got a multimillion grant from the National Institute of Health to study the effects of Urolithin A on the cognitive aging and how it can reverse some of the neuronal circuitry to look youthful. So we are actively looking at it and keeping our eyes and ears open for exactly feedback like this because brain cells also after muscle cells have the highest number of mitochondria that decline with aging.”

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Nov 13, 2021
The Best and Worst Foods for Your Metabolic System – Dr. Casey Means : 876
01:19:03

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

… you’re going to learn how to upgrade your metabolism and optimize your diet for your unique biology. 

 Dr. Casey Means started her career as a surgeon, where she saw firsthand, day after day, the devastating long-term consequences of poor metabolism, from cardiovascular issues to cancer. She decided to refocus her career on helping people prevent metabolic disease in the first place, instead of treating the results. 

 So, she began researching the causes of metabolic disorders. She quickly discovered a bigger and more subtle problem existed than she’d even realized. 

 “A recent UNC study estimated that 88% of American adults have at least one biomarker of poor metabolism,” she says. “And this is likely part of the reason why nine out of 10 of the leading causes of death in the U.S. are related to, or worsened by, dysregulated blood sugar levels.”

 What does this lead to? “Healthcare costs are going up each year...and we’re getting sicker, fatter, and more depressed,” Dr. Casey says.

 That’s why she co-founded Levels Health. Levels created a wearable device that continuously monitors your blood sugar levels, then gives you a personalized nutrition dashboard based on the results. 

Blood sugar imbalances are a strong predictor of inflammation and long-term metabolic disease. Keeping your blood sugar on an even keel is a powerful way to gain stable energy all day, keep your metabolism running strong, and even lose weight. 

Everyone’s metabolism is different, which is why Levels uses your personal data to make food recommendations. It can tell you which foods to eat, which ones to avoid, the best times to eat, and even whether you’re eating too much or not enough. 

I’m a big believer in quantifying your health. When you have objective numbers about your biology, you can start to tweak things and make them better.

Levels gives you the power to measure your blood sugar throughout the day—and Dr. Casey hopes that this kind of insight will help you eat better, lower your inflammation, supercharge your metabolism, and become a stronger, more capable version of yourself. 

In this episode, you’ll also learn about:

  • The worst foods for your blood sugar (quick preview: Chick-Fil-A and Coca Cola are at the top of the list)
  • How your metabolism affects everything from Alzheimer’s to acne to erectile dysfunction
  • Why the calories-in-calories-out model of nutrition is flawed
  • Simple changes you can make to build a stronger metabolism
  • And much more!

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Nov 12, 2021
Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio : 875
01:10:21

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IN THIS EPISODE OF THE HUMAN UPGRADE™…

you’re going to learn how to revamp your sleeping environment and get awesome sleep. 

If you aren’t hacking, tracking, and prioritizing your sleep, it’s time to start. 

Sleep is a pillar of high performance that affects pretty much everything you do. If you want to perform at your best, you have to get deep, restorative sleep. You know that, but are you doing it?

I’ve interviewed many sleep experts on my podcast. (Psst… I even created a 14-Day Sleep Challenge that teaches you how to hack your sleep.) 

This interview, however, is a bit different. I’ve invited a new kind of sleep expert on the show.

Jack Dell’Accio spent the past 16 years studying mattresses. He set out to hack every aspect of mattresses, from pressure relief to posture support to toxin-free materials. 

You know that plastic, chemical smell that fills your bedroom when you get a new mattress? That’s caused by off-gassing—a combination of volatile chemicals that turn into gas and fill the air in your bedroom as you break in your mattress. Research has found that many off-gassing chemicals are respiratory irritants and can cause you to develop chemical sensitivities[*][*]. They’re nasty compounds and you don’t want to spend eight hours a night breathing them in. 

That’s where Jack comes in. 

After years of research, Jack created a new type of memory foam – a natural rubber latex-based foam  that provides support and pressure relief, without the off-gassing irritants that you find in old school memory foam. 

Jack founded Essentia, the first mattress company that uses materials that are good for your body, your health, and your environment. It’s a major upgrade over memory foam, both in terms of sleeping experience and chemical content. 

Essentia manufactures its mattresses and sleep products in its own GOLS (Global Organic Latex Standard) and GOTS (Global Organic Textile Standard) certified organic factory. These are the two most important certifications when it comes to organic mattresses and organic mattress manufacturing. They’ve also had their mattresses tested by experts at Johns Hopkins.

In today’s episode, you’re going to learn the science behind building a better mattress, and why upgrading your mattress will improve almost every aspect of your body and brain. Jack and I also cover:

  • The many chemicals hiding in cheap mattresses 
  • Why, thanks to a backwards California law, most mattresses contain several pounds of flame retardant chemicals (and how Essentia makes their mattresses without those chemicals.)
  • Why 25% of NHL players use Essentia mattresses
  • The connection between cheap mattresses and chemical sensitivities
  • How Essentia created a proprietary EMF barrier foam formula
  • How a high-quality mattress makes your brain work better


A sleep surface has to have six key elements to establish a sleep environment that regenerates the body during sleep. Essentia mattresses score at the top of all six. Here’s what to look for:

  • Temperature Control (natural thermoregulation/ active cooling)
  • Allergy Friendly (allergen-friendly materials)
  • Accelerated Recovery (support and pressure redistribution)
  • Optimized Sleep (adaptive accelerated response to reduce movement interruptions)
  • Organically Clean (clean, non-toxic materials & an organic mineral formula that drives EMF patterns)
  • Proper Posture (eliminates negative space to properly support the back)


The mattress you sleep on matters just as much as all the other high-performance lifestyle choices you make. In this episode, you’re going to learn the science behind building a better mattress and why so many professional athletes choose Essentia.

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Nov 10, 2021
Finding Joy, Building Community and Raising Your Own Pork – Radha Agrawal : 874
01:12:57

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IN THIS EPISODE OF THE HUMAN UPGRADE™️... 

…you’re going to learn how to biohack joy—and why it’s simpler, and more necessary, than you might think.

Radha Agrawal is an author and successful entrepreneur with a singular purpose: to bring people together through joy and genuine human connection.

She’s the founder and CEO of Daybreaker, a morning dance, music, and wellness movement that spans five continents. Through Daybreaker, Radha has built a community of more than 500,000 people across the globe who wake up early to dance together.

She’s also co-founded, sold, and invested in multiple nine-figure businesses in the wellness space. MTV named her “one of eight women who will change the world,” and she recently toured with Oprah, bringing live music and dance to more than 150,000 people.

One of the things Radha has learned over the years is that, for all the superficial connection available in the Digital Age, people are starving for true community—and real human connection seems to be harder to come by now, not easier.

Radha thinks one of the biggest things we’re missing is vulnerability.

“Every single person listening right now has a backpack full of their own history,” she says. “So, we all carry around this invisible backpack with all of our history in it. [With real community], you start pulling out, ‘My father died in an accident,’ or, ‘this happened,’ or, ‘I got betrayed by this person.’ All of a sudden, there's a depth of tenderness...that’s where community starts.”

She goes deeper into the importance of human connection in her book, “Belong: Find Your People, Create Community, and Live a More Connected Life.”

This conversation meandered through several unexpected topics, too. Listen on to learn:

  • How to hack your brain for more joy (and how to quantify the joy in your life) – all backed by science
  • Why drugs are a poor substitute for human connection
  •  How to build true community in the Digital Age
  •  Why dance and music are the future of medicine
  •  How Radha went from a small idea to an enormous, successful company—without a single investor
  •  The bittersweet reality of being a pig farmer
  •  How pain and tragedy can make you stronger, not weaker
  •  The importance of forgiveness (and why we have to stop cancelling people)

 By the end of this podcast, you’ll have practical tools to become a more joyful person. 

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Nov 04, 2021
You Control Your Own Karma – Sadhguru : 873
00:42:41

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IN THIS EPISODE OF THE HUMAN UPGRADE™️...  

Sadhguru, a yogi, mystic, visionary and spiritual master who spreads wisdom around the world, clarifies the meaning of karma (no, it’s not a checklist of good and bad deeds) and explains how much you’re in charge of your own karma. 

His most recent book, “Karma: A Yogi’s Guide to Crafting Your Destiny,” breaks down the ways in which karma frames our lives.

“It’s time to unpack the most overused, abused and yet indispensable world in the spiritual vocabulary of the world,” says Sadhguru in his book. “It is time to examine how karma is connected to some of the most vital areas of human inquiry: the meaning of life and above all, how to live it.”

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Nov 02, 2021
Mini-Episode: Cool Facts Friday #16
00:11:44

In this Episode of The Human Upgrade™...

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.

  • Examining the relationship between autoimmunity and pain.
  • Plants up regulate their own autophagy to bring nutrients back in balance.
  • How autophagy supports stressed-out cells.
  • New genes found! Nearly three times more cause obesity than prevent it.


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FEEDBACK: Got a comment, idea or question for the podcast? Submit via this form!

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Oct 29, 2021
Discover Your ‘Sparketype’ and Meet Your True Self – Jonathan Fields : 872
01:04:49

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IN THIS EPISODE OF THE HUMAN UPGRADE...  

If you find yourself deeply questioning parts of your life that you haven’t before, you’re not alone. People are asking more existential questions about their lives than they were two years ago, and Jonathan Fields joins the show to guide you through some answers.

Jonathan maximizes human potential, especially in the realm of meaningful work. He’s the bestselling author of four books on self-development, most recently “Sparked: Discover Your Unique Imprint for Work that Makes You Come Alive.” He also hosts the popular Good Life Project podcast.

“I started into this topic two decades ago,” Jonathan says. “The fact that the last two years have dropped literally the entire world into the biggest existential questioning in generations is not something that I saw coming. But we are in that place, as we sit here depending on the research that you look at, anywhere from 25 to 50 percent of people either have quit their jobs or are in the process of quitting or seriously considering it.”

He aims to help people realign the work they’re paid to do, with the actual work that nourishes them through something called SparketypesThey’re the 10 different archetypes that are sparked by different kinds of work. You may be a maven, maker, scientist, essentialist, performer, sage, warrior, advisor, advocate or nurturer.

https://sparketype.com/sparketest/.Get started with the Sparketype quiz at 

Once you determine your particular Sparketype, it can be easier to find work that lights you up. Knowing your Sparketype also can lessen the fear of a career pivot and show you how to take your enthusiasm for one passion into a different line of work. You then can confidently build a career with a sense of purpose and direction.

“[People] may not know what the bargain is that they want to step into,” Jonathan explains. “But what they're getting clear on is the fact that the way that work has made them feel has satisfied certain needs, for sure, security, safety. The more existential needs, which tend to really become more important when we get a little bit further in life, those have generally been set aside. Part of that bargain was maybe later. Later is here.”

Enjoy the show!

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Oct 28, 2021
Moving Through Fear’s Allure to Find Inner Peace – Akshay Nanavati : 871
01:14:37

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IN THIS EPISODE OF THE HUMAN UPGRADE...

Akshay Nanavati’s story of perseverance includes overcoming drug addiction, alcoholism that pushed him to the brink of suicide, depression and PTSD from fighting in Iraq with the U.S. Marines.

“That's when I fell in love with the experience of adversity and the struggle because boot camp was terrifying,” Akshay says. “Everything about [it] was terrifying but it was so alluring that I started to look for other ways to confront myself—ultimately to go to war with myself.” He believes that the path to inner peace is the pursuit of a worthy inner war. 

He went on to build a global business, run ultramarathons, conduct humanitarian work in post-conflict zones, and explore some of the most hostile environments on the planet—from mountains to caves to polar icecaps. Nature became my playground to explore my fears and ultimately, systematically push through them one inch at a time.”

“I craved a high I believed I could only get by living on the edge of life and death,” he says in his book, “Fearvana: The Revolutionary Science of How to Turn Fear Into Health, Wealth and Happiness.” 

He’s also spent years extensively researching neuroscience, psychology and spirituality. He combined his life experience with that research to write “Fearvana” and infused it with ways to transform fear, and its counterparts stress and anxiety, into something much more positive. His Holiness the Dalai Lama wrote in the book’s foreword, “Fearvana inspires us to look beyond our own agonizing experiences and find the positive side of our lives.” 

Akshay now teaches people how to overcome their own fears and how to tap into their brain’s superpower—neuroplasticity.

Sounds good, but how do you really move through stress and attain growth? First, you have to learn to disidentify with fear and suffering by remembering you are not your thoughts, feelings or experiences, Akshay explains. “You are simply the one who experiences them. Through this process it becomes so much easier to create a life of fulfillment, It’s a lifelong practice and a great pathway to growth.”

You can even learn to "suffer well" in the day-to-day context of your human experience.

“I couldn't care less when fear shows up,” he says. “What matters to me is what I do with it once it does. I can let go of the construct I have around the fear and accept it for what it is and then choose what I want to do outside of it.”

Take a listen for more tips on how to become fearless. 

Akshay heads to Antarctica in early November 2021. Learn more about his South Pole journey and how to follow along here.  

Enjoy!

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Oct 26, 2021
It's Time for an Evolution: The Human Upgrade with Dave Asprey : 870
00:22:03

Across 10 years and nearly 1,000 episodes, this podcast elevated what you knew about the capabilities of your mind and body.

Now, I’m evolving it even further in my plan to upgrade humanity.

I invite you to Expand KnowledgeExplore Performance and Embrace Possibility with The Human Upgrade.

You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable.

People from around the world who elevate what it means to be human.

 People who choose danger when it's worth it. Just like you. 

What are you going to learn from these people in the domains of your biology, your body? What are you going to learn about your mind, your thoughts, your habits, the way you show up in the world, and what are you going to learn about the spiritual side of things? The personal development side, that weird space where you wake up and there's a dream in your mind. What does it mean?

You can't just focus on one if you want to be an upgraded human. You upgrade all of them. You start with your hardware. Because when your body works right, you have enough electricity. When you have enough electricity, then you can handle the things in your life that need handling. And you can say, "Well, I have some energy left over. What will I do with it?"

Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.

Join me on this next evolution to upgrade your mind, body and life. 

Enjoy! Got a comment, idea or question for the podcast? Submit via this form.

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Oct 26, 2021
Tap Into Your Brain’s Full Potential – Patrick Porter, Ph.D., with Dave Asprey : 869
01:07:59

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IN THIS EPISODE OF BULLETPROOF RADIO...  You’ll find out how award-winning speaker and author Dr. Patrick Porter developed tools that help your brain access its optimum state through brainwave entrainment. 

Brainwave entrainment means that different sounds, like Binaural Beats and Isochronic Tones, are pulsed into each of your ears to stimulate your brain into an altered state of consciousness. In a good way! This can improve your focus, energy, relaxation and deep sleep.

Using guided meditation, Dr. Porter’s BrainTap device uses a neuro-algorithm to synchronize your brainwaves to a specialized sound. That results in full-spectrum brainwave activity. Each session ensures the brain’s ability to reorganize itself by forming new neural connections, also known as neuroplasticity.

Dr. Porter has been a leader in brainwave entertainment tech for more than three decades years. He previously developed the world's first personal sound and light brain-training machine, the mc2, and created a Behavior Repatterning device. He’s written several books about the brain, including: Awaken the Genius: Mind Technology for the 21st Century; Discover the Language of the MindThrive in Overdrive: How to Navigate Your Overloaded Lifestyle; and  Awaken Your Flourishing Brain.

Dr. Porter continues to widen the scope of what we know about brain capabilities and performance. He says,” We've got this globally world-class brain that can do incredible things for us,” but people often aren’t listening to it.

“Once we started being able to measure the brain, we could track how the brain changes,” he says. “We know that every three to five seconds, we need to make a change or interrupt the pattern. If not, the brain will go “bye-bye,” – it's like advertising. The brain only has so much.”

BrainTap increases your production of neurotransmitters, leading to a more balanced brainwave state. Even if you can’t stay in that balanced brain state, the feeling of that optimal mode will stick with you and will be within reach at all times. It’s like a flow-state from meditation if you’ve experienced that. But you don’t have to be a meditation expert to experience benefits. BrainTap allows even complete beginners to see immediate progress

You can do the BrainTap sessions at different times of the day when you naturally lose energy, helping you with things like sleep, focus, concentration, mindfulness, memory, stress and anxiety. The sessions also have been shown to increase athletic performance and recovery, and even help with addictions.

In this episode, Dr. Porter explains the four elements of BrainTap, including Binaural Beats, Guided Visualization, 0-Cycle Holographic Music and Isochronic Tones. You’ll get to geek out on all the ways your brain affects your body (and vice-versa) and learn what you can do to reach your full brainiac potential.

 “Our brain actually is always syncing to its environment,” Patrick says. “That's why if it's chaotic {that it’s] causing some disruption. You have to filter it out. You have to learn how to do that.” 

Don’t miss Dr. Porter’s IG Live! Hacking Your Brain with Light and Sound.

Enjoy! Got a comment, idea or question for the podcast? Submit via this form.

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Oct 21, 2021
Be Your Own Hero: Take Risks, Face Your Fears and Choose Courage – Ryan Holiday with Dave Asprey : 868
01:18:33

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IN THIS EPISODE OF BULLETPROOF RADIO... you’ll discover what it takes to be courageous and heroic in your own life.

The Spartans used to build temples to fear. They did so to keep fear close, see its power and ward it off. Modern-day philosopher Ryan Holiday is here to tell you how to do that in your own modern life by using courage to overcome fear.

“You can have that reaction [to fear], but then you also realize, if you don't act on it, if you push through, there's often something on the other side of it,” Ryan says. “Or you realize that the more you expose yourself to it, the less scary it is each time and the less perhaps even that you feel that thing.”

Everyone experiences fear, but those who can learn to go beyond it will find room for courage. His most recent book, Fear is Calling: Fortune Favors the Brave is compelling and empowering. It breaks down what it means to confront fear, courage and heroism in order to discover your own grace and wisdom. 

We talk about how to transform fear into courage and the power of choosing the relationship you have with fear.

“Man, people get really uncomfortable when something that they were told by their parents, or their church, or their society, or their social media, and all of a sudden, they face profound evidence that it's not true,” Ryan says.

Pulling stories from some of the greatest humans in history he talks about how heroism can change the world, and how history can help guide you through contemporary phenomena rooted in fear, like cancel culture and government mandates. 

This is the first book in Ryan’s new series on the four virtues of the ancient world: courage, temperance, justice, and wisdom. 

Don’t miss Ryan’s previous visit to Bulletproof Radio and the discussion about stoicism and ego: Modern Stoicism & Crushing your Ego: Ryan Holiday #527

Enjoy! Got a comment, idea or question for the podcast? Submit via this form.

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Oct 19, 2021
How Measuring Brain Function Leads to Performance Upgrades – David Oakley, Ph.D., with Dave Asprey : 867
01:14:34

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IN THIS EPISODE OF BULLETPROOF RADIO... 

I talked to the co-founder of WAVi at the 7th Annual Biohacking Conference in Orlando, Florida. Physicist David Oakley created a device that’s used to directly measure brain function and gives you a 360-degree assessment of your brain performance.

WAVi is an all-in-one measurement platform. Users get objective information about brain function through EEG, visual ERP, auditory ERP, heart rate variability (HRV), Trail Making, standard assessments and more. This full FDA-regulated Class II device measures biomarkers of your brain with detail and precision in under 15 minutes.

“People measure their weight every day, right?” David says. “Step on the scale, “Where am I at today?” So, we should be measuring our brains regularly. Someday there will be WAVi in doctors’ offices and you’ll check your brain like you check your weight.”

For an introduction to WAVi, listen to Bulletproof Radio episode #619: Your Brain Voltage: Measure It, Raise It, Control It

In this interview, David and I go really deep into the science behind WAVi’s development. We get into physics, neuroscience, brain data, scientific inquiry and what’s exciting about the future of brain performance research. 

David comes from a long family line of inventors and creators. His own career as a physicist includes research and teaching at universities. He was also a researcher at the Los Alamos National Laboratory and has analyzed data within neutrino astrophysics, a branch of astronomy that observes astronomical objects with neutrino detectors in special observatories.

He has published research and articles in the areas of physics, medicine, and art. At mid-life he turned to brain data and created WAVi: a mix of art, science, commerce, and public service.

He made the move to study the brain when he met a fellow scientist David Joffee. “He started showing all the [brain] patterns, and I thought, “This is beautiful,” David says. “It's beautiful waves. You can do a lot with it. You can help people. It's about the same as physics, though. It's the same, just voltage versus time series data.”

David’s now exploring multiple brain topics, including concussions, Alzheimer's, Dementia, and mental health.

You’ll also find out why P300 continues to be an important signature of cognitive processes. It’s a 300 millisecond time frame that measures brain activity. This includes attention, working memory and dysfunction in neurologic and mental disorders. Ongoing research sees it as a potential genetic marker of mental disorders.

“As you age this performance drops and the speed drops,” David explains.

And then there’s voltage activity that’s happening in the brain. And if you can assess and measure what’s going on in your brain, you can do something about it.

So, this is a really big thing. And I want you guys to think about this. Right now you might be saying, "I'm not a brain scientist, I'm just listening to this." But there's, how fast does the brain respond? And how strongly does the brain respond? Because those are different things. And the reason my brain does what it does, I would say is clearly nutrition and mitochondrial enhancement and supplements and all that kind of stuff.

It's a fascinating time to be upgrading your brain!  

“So, 10 years from now, the happy path is that with the brain scan, the artificial intelligence will know you and know what you need to optimize your brain,” David says. “There won't be a question of, in the ideal world, it's not a question of your brain is slowing down. It will know you on day one and say, “This is what you need to do. As long as you stay with this program, you're going to have an optimized brain. It's not going to slow.” That's my 10-year future.”

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Oct 15, 2021
Clean Up Your Mouth! Saliva, Gums & Kissing Bad Bacteria Goodbye – Trina Felber with Dave Asprey : 866
01:11:32

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IN THIS EPISODE OF BULLETPROOF RADIO... you’re going to find out how your oral health and gut microbiome are connected.

My guest today is Trina Felber, RN, BSN, MSN, CRNA, the creator and CEO of Primal Life Organics, an all-natural health product company that specializes in oral health and skin care.

After more than 25 years as a registered nurse and nurse anesthetist, Trina turned her attention to the mouth microbiome and how it influences all your body systems--whether you know it or not.

She focuses on oral health as the gateway to internal health, so discuss topics that could give you clues about your own biology:

  • Saliva is the “lifeblood” of the mouth; 
  • Red light (and blue!) can improve gum tissue; and
  • What you must stop doing when brushing your teeth and why it matters so much to your oral health.


Your Saliva: “Saliva is a secretion no one's talking about,” Trina says. “And it's one of, if not the most important secretion in your body, because it does so many things, including nitric oxide production. If you have an imbalance in the microbiome inside your mouth and inside your gut, nitric oxide declines and your body can't produce nitric oxide. … Nitric oxide is a vasodilator, it's related to internal health, it's anti-inflammatory, it creates better sleep and better brain function.”

Your Gums: “Red light therapy is going to help with the condition of your gums, it's going to improve the overall environment inside your mouth, and it's going to help with the right environment to grow the right bacteria that in the long-term is going to help with nitric oxide production,” Trina says. “Red light therapy actually penetrates your gum tissue and will increase blood flow and reduce inflammation of the gum tissue.”

Your Brushing Habits: “Brushing too hard, we don't think about it, but it's common sense, but we still do it because you feel like you need to scrub to get your teeth clean and your gums,” Trina says. “But a lot of people just brush way too hard. It's really a soft motion. The softer you brush, the more you actually stimulate detoxification and increase blood flow. It's like a massage. Sometimes when you massage too hard, you create inflammation, you create more problems. And the softer that you massage, like lymphatic massages, are extremely, there's no depth to them. It's very light touch.” (Even with a sonic toothbrush!)

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Oct 13, 2021
Mimetic Desire Shatters the Myth of Why You Want – Luke Burgis with Dave Asprey : 865
01:27:45

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IN THIS EPISODE OF BULLETPROOF RADIO...

Do you know why you make choices that are bad for you? Or why you end up with burnout, bad diets and other things that cause you harm, when you know you’d be better off choosing something else? 

This episode cuts through the noise, everything you’re sold and told to want, and helps you answer those very questions.

Luke Burgis researched and studied the theory that underlies your tendency to follow other peoples’ wants, called mimetic desire. Explored by prominent French thinker René Girard, mimetic theory of desire says humans don’t want anything autonomously and independently. 

“Girard discovered that we come to desire certain things not through biological drives or pure reason, nor as the longing of our deepest, most authentic selves, but through imitation,” Luke says in his book, “Wanting: The Power of Mimetic Desire in Everyday Life.” Desire, as Girard used the word, does not mean the drive for food or sex or shelter or security. But after meeting those needs, we enter the domain of desire. And knowing what to want is much harder than knowing what to need.”

In studying the work of Gerard, Luke realized that his goals and dreams were a product of other people’s expectations of him and he was actually following the desire of what he was seeing in others (that’s why he was miserable, burnt out, in poor physical health and felt horrible).  

“The truth is that desires are derivative, contagious, and therefore competitive, and that’s why they often lead to conflict,” Luke explains. “The lie is that I want things entirely on my own, uninfluenced by others. By rejecting the truth, I deny the consequences of my desires on other people, and theirs on me.”

Luke and I dive into how to get past the innate desires of success and wealth that most of us are taught to value and really move into your own individual dreams and self-desires. 

“Mimetic desire exists on a spectrum,” he says. “And that there are some things that can't be explained medically at all. Something beautiful like a sunset, or like a beautiful woman that I'm attracted to. There are very clear scientific sort of physiological things going on there. So, let's make a distinction. Mimetic desire exists on a spectrum where those hardwired physiological things like thirst and hunger, those have been met, right? And we're sort of now in a more abstract world.”

Armed with this knowledge, you can make better choices about who you trust and build self-awareness around your choices to empower your own life. You can find holistic models that work for you in all areas of your life (not just at your job), and why those models are important to find sooner rather than later.

“​​The constant looking to what other people are doing or saying or wanting, or achieving, is just the fastest way to be miserable for one thing, but also the fastest way to miss opportunities, because we're just constantly looking to our right and our left rather than forward or up,” Luke says.

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Oct 08, 2021
Relationship Goals: Your Gut Microbiome and Immune Function – Kiran Krishnan, Ph.D., with Dave Asprey : 864
01:32:07

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IN THIS EPISODE OF BULLETPROOF RADIO...

Research microbiologist Kiran Krishnan, Ph.D., explores the world of microorganisms inside your body. He studies the human microbiome and knows just how much inflammation damages your gut and how your immune system fixes it.

He’s particularly adept at explaining practical ways to apply the latest science he’s uncovering.

His expertise lies in the newest frontier in microbiology—gut commensal spore bacteria. He partners with Just Thrive Health on prebiotics, probiotics and other gut health product development.

When he was on the show previously, we got into probiotics and immune health. (Don’t miss those! Support Immune Health in Two Steps: Modulate Gut Bacteria & Neutralize Inflammation – #677 and Armor-Plated Immortal Probiotics from Space – #629. This time, he makes connections between your microbiome and immune function.

“The inflammatory response is the biggest driver of gut related damage that occurs,” Kiran says. “You can also eat foods that are absolutely toxigenic to your microbiome.”

The good news? Up to 80 percent of your immune system lies in your digestive tract, Kiran explains. “Your immune system is there, ready and waiting to help with the situation.”

In this episode, you’ll learn that lipopolysaccharide (LPS) is the unknown villain of virtually everything. Kiran says it causes damage to the brain, contributes to metabolic disease, drives Alzheimer’s, Parkinson’s, and is the No. 1 driver of diabetes (to name a few).

“LPS is the most pervasive toxin we have to deal with and it’s an endotoxin, which is a key because we can’t get away from it,” Kiran says.

Kiran has a strict research background in the fields of molecular medicine and microbiology. For nearly 20 years, he’s conducted dozens of human clinical trials in human nutrition through his research organization: Clinical Research Organization.

His recently published leaky gut study showed reversal of gut enteropathy within 30 days. He’s now involved with a longer, more extensive leaky gut trial. 

His current research also includes nine other ongoing human clinical trials. Some test the effect of gut commensal spore probiotics on conditions like Thyroid/Hashimoto’s, Irritable Bowel Syndrome and liver failure.

Listening to this extensive interview, you’ll find out cool stuff, like what faecalibacterium prausnitzii is and how it helps you.

“We all have all kinds of damage occurring in our large bowel all the time,” Kiran says. “But if you have faecalibacterium, it's constantly repairing it. If you don't have faecalibacterium, at some point, the damage overcomes the repair and you start getting significant inflammation in lining which then puts you at risk for things like inflammatory bowel disease. Right, so we're constantly battling this state of damage, oxidative stress, inflammation, and all that, and then repair recovery and so on. And then as it turns out, microbes are so important for that repair and recovery phase.”

You’ll also gain new perspective of your own body biomes and the broader world:  “I've always referred to the human system as a walking, talking rainforest,” Kiran says. “We are a holo-biome which is a super organism. We are an organism made up of a collective of organisms that together in a certain balance will function and work. But we are also in constant osmosis with the ecosystem, and we're designed to be that way.”

Another positive for your gut and immune health is the vast number of microbial genes in your system.

“We have such limited amount of genetic capability as a species,” Kiran says. “We barely have enough genetic material as an earthworm does, and so we're not that cool or sophisticated. What makes us as sophisticated as we are, is the two and a half million or so microbial genes in our system. And so, being able to outsource functionality to microbes is a big part of being human. There are sets of organisms that we have outsourced through the course of evolution, the ability to modulate and monitor the rest of the microbiome. We're finding that when you start putting in these microbes back into your system, you really start getting the positive changes. They start refereeing the ecosystem and making things more balance and improved.” 

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Oct 06, 2021
How to Build Strength Faster – John Jaquish, Ph.D., with Dave Asprey, Part 2 : 863
00:44:07

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In Part 1 of our two-part episode with John Jaquish, Ph.D., I talked with him about building bone density—an important factor in your strength and longevity. Don’t miss! Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D., with Dave Asprey, Part 1 – #862.

This inventor, author, and scientist created OsteoStrong and the X3 System, a series of devices that combine rehabilitation and advancements in human physiology to build bone density. His extensive research into bone density and strength found that you can approach weight lifting much differently than you may think.

“It appears that the most biological adaptation comes from not the area under the curve, the total volume of work you did, but has to do with how quickly did you go from zero to 100 and back to zero,” John says. “So, a very brief spike of almost anything causes way more adaptation than spiking up to 70% and holding it.”

Now in Part 2, our conversation dives into John’s other findings and lifestyle choices, both as a public figure, a mentor for professional athletes and a fasting enthusiast. We go off the beaten path on a few things:

  • Anabolic rebound after fasting (what fasting does to build muscle mass)
  • Tendon mutations (and how they make people outrageously strong)
  • Taking Viagra (or other non-pharmaceuticals) and carbs to trigger a muscle cell splitting
  • The difference between fructose, glucose and sucrose (is there any real difference in the body?)


We also talk about ways to eat for strength and the quest for longevity that guides him. He knows about the tempting danger of eating to only look good (but you feel like crap). He offers tips to make sure you don’t go there.

Check out John’s book to learn more: Weight Lifting Is a Waste of Time: So Is Cardio, and There’s a Better Way to Have the Body You Want

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Oct 01, 2021
Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D., with Dave Asprey, Part 1 : 862
00:39:45

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IN THIS EPISODE OF BULLLETPROOF RADIO...

Inventor, author, and scientist John Jaquish, Ph.D., downloads his knowledge about the importance of bone density. When his mom was diagnosed with osteoporosis he set out to develop bioDensity, a system that builds bone density by triggering the effects of weightlifting without the risk of injury. He’s talked about it on Bulletproof Radio before.

He’s developed a way to put on muscles three times faster than you can by weightlifting. I’m asking him to explain why that matters and what devices and routines can help you get there. He created OsteoStrong and the X3 System, a series of devices that combine rehabilitation devices and advancements in human physiology to build bone density. 

Why so much focus on bone density?

“You're avoiding the potential for fragility fractures later in life,” John says. “The bone you build through the osteogenic loading process, through this heavy loading, you're getting bone built that's going to last in your body for 30 years. It doesn't go away like muscle. Detraining of a muscle starts in 10 days. If you stop working out, you lose your muscle in 10 days. It takes you 30 years to lose the bone.”

In part one of this two-part episode, we talk about John’s inventions and research, as well as the three aspects of strength that most people don’t think about when they start a fitness routine. You’ll learn what vitamins and protein habits matter and what kind of exercise truly increases your longevity.

You can also check out John’s book: "Weight Lifting Is a Waste of Time: So Is Cardio, and There’s a Better Way to Have the Body You Want"

And stay tuned for Part 2 of this episode, coming soon!

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Sep 29, 2021
Mini-Episode: Cool Facts Friday #15
00:12:51

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Enjoy!

Here’s the current lineup for episode #15:

  • A ketogenic diet impacts brain cancer.
  • A surprising connection links calf muscles, blood pressure, and dementia risk.
  • A dose of sunlight boosts romantic passion.
  • An energy process involves brain cells, memory and sugar levels.
  • A bunch of benefits support time-restrictive eating.
  • An innovative way to transport mouse sperm.


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Sep 24, 2021
Hack Your Neurochemistry with Customized Nootropics – Mr. Noots & Matt Gallant : 861
01:22:48

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IN THIS EPISODE OF BULLLETPROOF RADIO...

We’re going deep on all things nootropics. Stacks, timing and what works for your brain.

I didn’t want to be the guy who made nootropics. I wanted it to be the fact that it’s possible, therefore, let’s all do it. I mean, take them and let’s all make them. We need creators who build stuff that’s real. I just want people to see it was real so that we could all build it.

You’re going to learn a lot in this episode, like:

  • The promise of nootropics vs. the reality of nootropics
  • Problems with typical nootropics
  • How brain chemistry and nervous systems are incredibly unique
  • How every high-performance state has a corresponding neurochemistry stack
  • Nine Nootopia base blends that have specific goals and purposes
  • Why Nootopia nootropics are different
  • Tips to get the most out of your nootropics

 

One of today’s guests has been on the show several times to talk about psychobiotics, magnesium, enzymes and blood sugar.

As co-founder of BiOptimizers, Matt Gallant keeps researching and innovating ways to keep your whole body healthy. He sees important connections within body systems and finds unique ways to maximum human performance. He especially likes the brain and will be talking about new developments in nootropics that can be customized to your own body system.

Matt Gallant: “A lot of nootropics rely on brute force,” Matt says. “They hammer one receptor or one pathway and they just push it to the max which has negative consequences, receptors downregulate, you can have more side effects. As a former addict, I thought, and I was hardwired to believe that more is better. And now I know better and optimal is better. So, it's about really finding the optimal dose for each person. And that's why we're all about customization and personalization.”

He’s joined by Mr. Noots, his partner in custom nootropic development. 

Between ages 5 and 10, he built radio, conducted dangerous chemistry experiments and built a Helium-Neon Laser from scratch. His favorite childhood activities were science, chemistry and physics. He spent his 20’s in the US Air Force, which was the perfect platform to become an endurance athlete and eventual bodybuilder. Life happened and as Mr. Noots moved from sick to superhuman, he dove deep into performance-enhancing nutrition. That, in turn, led him to become a Chief Product Officer for the mind-enhancing compounds and stacks of nootropics at Nootopia.

“This is one of the things where I want everyone listening to just say, "Okay, I admit to myself that it is possible for plant extracts or other compounds to improve cognitive function because it's abundantly obvious,” “says Mr. Noots.

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Sep 24, 2021
Nutrition Goes Primal with Dr. Paul Saladino and Nora Gedgaudas : 860
00:26:33

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IN THIS EPISODE OF BULLLETPROOF RADIO...

You've been asking for experts who can talk about food that's in line with the way we evolved as humans, so this episode brings together two guests who are experts on ancestral eating: Dr. Paul Saladino’s research on the carnivore diet, with Nora Gedgaudas decades of research on paleo and keto diets.

The conversation dives into the dangers of vegan and vegetarianism, why meat should be a core part of your diet, and how plants might be more harmful to eat than you think. 

Both put chronic disease at the core of their research and have spent years of research and heart finding eating habits that give you the greatest quality of life. 

Dr. Paul Saladino is a certified functional medicine practitioner who says yes to meat and no to plants. Dr. Saladino’s work promotes the use of science-based information to deeply understand the root causes of illness and provide individualized care that goes beyond traditional pharmacological treatments.

“Eat nose to tail with organ meats, with well-raised red meat and organs, and you will thrive,” Dr. Saladino says. “Plants hate us and if we ignore the fact that plants exist on a toxicity spectrum and make plant toxins, which are defended chemicals, we are abandoning a whole bunch of people who could get really well by eliminating the most toxic plants from their diet.”

Want to learn more from Dr. Saladino? Listen to two full podcasts with him and check out his book:

 

Nora Gedgaudus is an internationally keto and ancestrally based nutrition specialist and author. She combines extensive research with evolutionary physiology, biochemistry, metabolism, nutrition, and chronic and degenerative disease for mind-body health and longevity.

She’s created her own program called PRIMALGENIC, based on her 20 years of knowledge of ancestral and modern eating, and the paleo and keto diets.

“What’s incumbent upon us in the face of so many things we feel like we can't control is to take control of what we can, be aware, understand as much of this as we can and find ways of strategizing our way around the system and develop that firsthand knowing of where your food comes from, as much as humanly possible,” Nora says. “And, educate yourself and take responsibility for as much as you possibly can.”

Want to learn more from Nora? Listen to two full podcasts with her and check out her books:

 

Check out more articles from Dr. Saladino and Nora about ancestral eating on the Dave Asprey blog: 


Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Sep 21, 2021
Kava: Psychedelic Benefits in an Alcohol Alternative – Cameron George with Dave Asprey : 859
01:11:25

This episode of Bulletproof Radio revisits one of my favorite varieties of plant medicine, called kava. It’s a plant-based drink from the South Pacific Islands that relieves anxiety, boosts mood and enhances cognitive abilities. It has a pretty impressive resume: 

  • Kava is a safe, natural alternative to drugs and alcohol
  • Kava offers effects similar to micro dosing psychedelics
  • When humans consume kava, it helps protect the body from all forms of stress (physical, chemical, emotional) 

I’m talking with Cameron George, a researcher, writer, entrepreneur and the founder of TRU KAVA. He’s been on the show before, Kava Just May Be The Next CBD – #731, so don’t miss that one for a great starter resource! This time, we get into kava’s growing use in the United States, its links to community and social connection, and how it makes an amazing alternative to alcohol.

Cameron likes kava as an alcohol replacement, he says because [for the most part] “people who are migrating towards kava are looking for healthier alternatives that are non-addictive, that don't interfere with their faculties and kind of keep them sober, but bring kind of that enhanced sobriety.”

Kava lowers the emotional stress system in the brain that is overactive and easily triggered. It increases GABA, an amino acid which is a building block for proteins, and in the brain, kava acts as a neurotransmitter and activates serotonin.

“Whenever you talk to the indigenous people of the South Pacific,” Cameron says, “they don't speak of kava in the same context. In the U.S., we just see it as an anxiety relieving herb that helps with sleep and stress and things like that. They speak of it as a spiritual entheogenic medicine that improves the quality of your thoughts, your perspective, induces introspective thinking and allows people to connect with one another.”

TRU KAVA sets the industry quality standard by providing the safest and most effective kava on the market. The company offers kava oil and shots, and a new drink that you consume like you would an alcoholic beverage. I’m really excited for you to listen to this conversation, hear us break down some misconceptions and learn how you can experience the benefits of kava. 

Enjoy! And get more resources at Dave.Asprey/podcasts.

Got a comment, idea or question for the podcast? Submit via this form.

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Sep 16, 2021
Ozone Therapy: Your New Favorite Biohack – Micah Lowe with Dave Asprey : 858
00:50:32

Micah Lowe loves all things ozone. So much so that his nickname is the “Ozonaut.”

In this episode of Bulletproof Radio, you’ll find out how ozone therapy improves your body’s intake and use of oxygen and activates your immune system. Micah’s company, Simply 03, develops equipment for people to conduct affordable ozone therapy from their own homes.

“So, there’s a whole world of ozone that you can dive into,” Micah says. “There’s ozone for municipalities. There’s ozone for wine making. There’s ozone for pools. There’s ozone for hot tubs. There’s ozone for aquariums, and then there’s medical ozone. They’re all different.

You may think ozone is a pollutant, but, in fact, it’s a really strong oxidant that alters your body at a cellular level and helps your mitochondria make more antioxidants. Ozone stimulates growth factors and increases oxygen metabolism. This in turn increases energy and stamina and reduces brain fog.  

“Ozone is actually similar to exercise in that it signals a pathway called the NRF2 pathway, where it's actually good for you,” Micah explains. “So, this can be good in terms of athletic performance because it'll help people to recover faster. It'll help them to diminish the effects of those workouts that are really tough.”

The other side of the ozone equation involves oxygen efficiency. Oxygen efficiency is important for being able to maintain higher levels of cognitive performance and for athletic performance, Micah says. “It's just a fundamental aspect of our lives that we all need.”

Simply O3 manufactures high-quality ozone generators, ozone kits, ozone skincare, and accessories. Since there are many kinds of ozone therapy, we cut right to the chase about how Simply 03 works, what makes it special and how to balance it with the rest of your body care and plan for your health.

There’s a cosmetic side to ozone, too. Micah co-founded the ozone cosmetic skin care companyHonest O3, with his brother. The company specializes in manufacturing and selling oxygen-rich cosmetics, such as creams and gels. 

You’re going to get a lot out of this episode’s deep dive into the many benefits of ozone therapy.

Enjoy! And get more resources at Dave.Asprey/podcasts.

Got a comment, idea or question for the podcast? Submit via this form.

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Sep 14, 2021
Speaker Preview 2: Human Upgrades at the 7th Annual Biohacking Conference : 857
00:49:47

Take a listen to a few of the world’s most innovative minds in the field of human optimization and biohacking. All will be speaking in person at the 7TH Annual Biohacking ConferenceSept. 17-19, 2021, in Orlando, Florida.

This transformative 3-day event, hosted by Dave Asprey and Upgrade Labs, features thought-provoking keynotes, panelists, and Upgrade U and Master U instructors. You’ll find a Tech Playground and fully immersive experiences that push the limits of human advancement, performance and longevity. 

Here’s a speaker sampling:

Vishen Lakhiani: Optimize the brain for prime happiness and performance.

Vishen Lakhiani: 10 Laws & Four-Letter Words – #309

Dr. Will Cole: Tame inflammation, calm cravings, balance hormones and find food peace.

Intuitive Fasting, Metabolic Flexibility & Metaphysical Meals – Dr. Will Cole with Dave Asprey – #796

Panache Desai: Be “enough” through the power of insight and energetic transformation.

You Are Enough! Find Your Authentic State with Panache Desai and Dave Asprey – #692

Don Wood, Ph.D.: Efficient and effective solutions for trauma using modern neuroscience advancements.

How to Stay Present No Matter What – Don Wood, Ph.D. – #648

Dr. Ted Achacoso: Bringing together AI, tech, human body systems and evolutionary medicine.

Mathematics of Consciousness -Your Life as a Video Game. Dr. Ted Achacoso #495

Whether you attend in person or are unable to join the conference, try the special conference edition of the DAVE ASPREY BOX. This quarterly subscription box gives you access to biohacking resources that can support you in achieving your health goals and unlocking your potential.

Enjoy! Got a comment, idea or question for the podcast? Submit via this form.

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Sep 09, 2021
Speaker Preview 1: Human Upgrades at the 7th Annual Biohacking Conference : 856
00:42:08

Take a listen to a few of the world’s most innovative minds in the field of human optimization and biohacking. All will be speaking in person at the 7TH Annual Biohacking ConferenceSept. 17-19, 2021, in Orlando, Florida.

This transformative 3-day event, hosted by Dave Asprey and Upgrade Labs, features thought-provoking keynotes, panelists, and Upgrade U and Master U instructors. You’ll find a Tech Playground and fully immersive experiences that push the limits of human advancement, performance and longevity. 

Here’s a speaker sampling.

Marcella Madera: A neurosurgeon gives prep tips for calming pre-surgery stress reactions.

Radical Regeneration: Neurosurgery Meets Energy Medicine – Marcella Madera, M.D. #582

Naveen Jain: What happens in the gut doesn’t stay in the gut.  

From Inside Your Gut to Outer Space: Moonshots with Naveen Jain #541 or Your Microbiome May be Misbehaving – Naveen Jain #612

Jim Kwik: Progressing and advancing beyond what you believe possible. 

Limitless: How Will Smith and the X-Men Got That Way – Jim Kwik Tells Dave Asprey – #695

 Joe De Sena: Get way out of your comfort zone.

Spartan Up! with Joe De Sena – Podcast #116

Dr. Elizabeth Yurth: Restoring normal metabolic health and strengthening your mitochondria.

Trigger Autophagy Without Fasting – Dr. Elizabeth Yurth Talks Spermidine with Dave Asprey – #773

Kiran Krishnan and Tina Anderson: Mucosal inflammation, gut lining damage, and repairing your microbiome.

Support Immune Health in Two Steps: Modulate Gut Bacteria & Neutralize Inflammation – Just Thrive Health – #677

Whether you attend in person or are unable to join the conference, try the special conference edition of the DAVE ASPREY BOX. This quarterly subscription box gives you access to biohacking resources that can support you in achieving your health goals and unlocking your potential.

Enjoy! 

Got a comment, idea or question for the podcast? Submit via this form.

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Sep 08, 2021
Build Your Career with 5 Keys of Emotional Intelligence – Caroline Stokes with Dave Asprey : 855
00:43:31

In this episode of Bulletproof Radio, you’ll learn about the different kinds of emotional intelligence and how you can use them to catapult your career and your business

As a human capital entrepreneur, Caroline Stokes specializes in creating emotionally intelligent organizations, starting with leadership.

“I take a broader view and define people leaders as anyone who manages people in any capacity,” she says in her newest book, “Elephants Before Unicorns: Emotionally Intelligent HR Strategies To Save Your Company.” “No matter where you stand in your organization’s hierarchy, I challenge you to embrace the mantle of ‘leader.’ Own your influence. Find where you can do the most good and then do it with all your might.”

She’s an executive headhunter, certified executive coach, certified EQ.2.0 practitioner, and CEO of the Canadian company FORWARD. Caroline works with major companies throughout Canada and the U.S. on the need for talent to develop emotional intelligence and resilience in the face of technological advancements.

She blends recruiting and emotional intelligence strategies essential to helping companies identify and tackle elephants and acquire and retain key hires―those unicorns. We talk about how those strategies can help your company stand out, stay resilient, and drive growth.

“When we do executive search, the organizations will ignore those elephants in their organization because they want these really shiny, super smart, highly unobtainable unicorns to join them,” she says, “But they can't because they haven't reworked the systems within their organizations.”

In this episode, Caroline walks us through organizational obstacles, gives easy-to-implement advice, unpacks key emotional intelligence factor, and offers questions for reflection so you can unlock your team's ability to hire the best candidates for the job. 

Enjoy! And get more resources at Dave.Asprey/podcasts.

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7TH ANNUAL BIOHACKING CONFERENCE: SEPTEMBER 17-19, 2021: https://www.biohackingconference.com

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Sep 03, 2021
A Trio of Career Experts Say Yes to Criticism, Ideas and Mentors with Dave Asprey : 854
00:31:38

How’s work working for you?

Maybe your normal sources of inspiration have run dry. Maybe you keep getting stuck on the same series of tasks you can’t quite figure out how to do. Or maybe, you feel like no one’s telling you the truth about how you work. 

In this episode of Bulletproof Radio, three experts give you real-time tips on how to level up your career. 

The truths they share are designed to stimulate many aspects of your career. Steven HerzJeffrey Madoff and Kevin Harrington have helped people find not only success, but also passion and creativity in their work.

If you like this special episode with Steve, Jeff and Kevin, dive deeper into their expertise by listening to the full Bulletproof Radio podcasts:

Embrace Criticism and Don’t Take Yes for An Answer – Steven Herz with Dave Asprey – #745


Feeling Stuck? 40+ Ways to Turn Your Ideas Into a Career – Jeff Madoff with Dave Asprey – #744

  • Jeff Madoff discusses three stages of creativity, including inspiration, growth and stagnation, and how you can get started and keep the cycle going, despite stagnation. Check out his book: “Creative Careers: Making a Living with Your Ideas,”


Want to Make Millions? Get a Mentor – Kevin Harrington with Dave Asprey – #743


Enjoy! Got a comment, idea or question for the podcast? Submit via this form.

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Sep 01, 2021
Mini-Episode: Cool Facts Friday #14
00:12:20

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Enjoy!

Here’s the current lineup for episode #14:

  • CBD linked to Alzheimer's prevention
  • Reducing stress could reverse gray hair 
  • A new device detects bad breath
  • Spirituality found in brain circuitry
  • Inflammatory clock of aging determines your "immunological age" 


EPISODE SPONSOR: Learn more about the benefits of nano-emulsion CBD at https://joyorganics.com. Use code DAVE to save 20% off the entire product line

7TH ANNUAL BIOHACKING CONFERENCE: SEPTEMBER 17-19, 2021

Dave Asprey and Upgrade Labs host a transformative 3-day event featuring thought-provoking keynotes and fully immersive experiences that push the limits of human advancement, performance and longevity. You will connect with the world’s most innovative minds in the field of human optimization and biohacking. Join the community, at the Hyatt Regency Orlando, Florida. https://www.biohackingconference.com

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Aug 27, 2021
Stabilize Your Blood Pressure Using Biofeedback – Mackay Rippey with Dave Asprey : 853
01:01:23

Let’s not sugarcoat it; both low blood pressure and high blood pressure are bad for you. With either, you can experience an inability to focus, dizziness, heart disease, and other health problems. You want to find a way to stabilize your blood pressure in the Goldilocks zone–just right.

Controlling blood pressure is especially important when it comes to heart disease, which is the leading cause of death for men, women, and people of most racial and ethnic groups in the United States. There used to be a significant gap between men and women in the incidence of heart disease, but that gap has closed over the past few decades and now women die of heart disease as frequently as men.

In this episode of Bulletproof Radio, I brought on an expert to talk about Zona Plus. Mackay Rippey serves on the Medical Advisory Board of Zona Health. He explains how the biofeedback device helps you train your own body to change your blood pressure, using isometric exercise. In this kind of muscle contraction, the muscle is tensed and working, but not actively shortening or lengthening. The Zona Plus looks like a joystick from a fighter airplane with a little digital screen on top. That screen gives you immediate feedback.

Let's jump right into some of the biochemistry that I found with Zona, Mackay says:

“I started with the hand grip. So, 30% is the magic Goldilocks percentage for your grip. So, you need to calculate what your grip strength is in the morning. It can vary from day to day and the optimal is 30%. Now, if you think you can calculate 30% just by knowing what you're feeling, you're sadly mistaken. That's why it helps to have a biofeedback device that tells you, "You're at 30%. Oh, and, by the way, you have to hold it for two minutes." So, if you think you can do that for two minutes, you need a feedback device. It just makes your life a lot easier.”

We discuss the effects of pre-hypertension and hypertension on your health, how to manage your blood pressure and how to keep your cardiovascular system functioning properly. We also get into nitric oxide, endothelial cells and red blood cells.

Eighty percent of Zona Plus users lower their blood pressure back to normal because Zona makes biofeedback so accessible. It leads to greater cognitive function, clears toxins from your body and more. Consider this hand-held device your cardio biohack. We also talk about the additional supplements you can take to pair with the Zona for faster and better results.

And for those of you who may think it’s too early in your life for Zona Plus, that you’ll use it when you’re older, Mackay says to remember this: “Now's the time to start ‘exercising,’ your endothelial cells so that they continue to function well as you increase your age so you're not only living longer, but you're living well as well.”

Mackay sees the impact of blood pressure across many areas of health:

  • He co-founded Beyond Protocols, an education accelerator for Functional Medicine practitioners. 
  • He formulates supplements for cardiovascular health that reduce blood pressure. 
  • He’s operated Mackay Rippey Acupuncture for more than 30 years. 
  • He hosts Lyme Ninja Radio, a podcast focused on the challenges and treatment of Lyme disease. 
  • And, he’s got a passion for nutrigenomic research.


Join us for this important conversation on heart disease, healthy hearts, the blood pressure rollercoaster and some key elements to creating a long healthy life.

Note for listeners: I previously interviewed Zona’s CEO, Mark Young. Learn more about Zona’s company history and how the device was developed in episode #601: Get a Grip on Your Blood Pressure

Enjoy! And get more resources at Dave.Asprey/podcasts.

Got a comment, idea or question for the podcast? Submit via this form.

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Aug 27, 2021
3 Dimensions of Longevity That Will Extend Your Life – Sergey Young with Dave Asprey : 852
01:10:05

Sergey Young has his finger on the pulse of all things longevity. He’s spent years connecting with the world’s anti-aging research leaders. 

He’s learned that living to 200 years old and beyond is not only possible — it’s inevitable. 

When Sergey was on Bulletproof Radio episode #715, he and I talked about ways to make longevity affordable for everyone. Now he’s back with a new book, The Science and Technology of Growing Young: An Insider’s Guide to the Breakthroughs that Will Dramatically Extend Our Lifespan… and What You Can Do Right Now.

In this new episode of Bulletproof Radio, he explains how medicine and technology advances are rapidly paving the way for the long and healthy future of the human race. He lays out three dimensions to longevity: prevent premature death, life extension and age reversal.

“So you just need to keep your body and your mind in a state which is worth expanding its resource,” Sergey says. “And then it comes down to the full horizon of longevity, which is going to be available to us in 25 to 50 years.” 

He also debunks the most popular myths about longevity: living more means living less, longevity is dangerous and selfish, and life extension is not really poss